nifedipine and candesartan

nifedipine has been researched along with candesartan in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (36.67)29.6817
2010's18 (60.00)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Abe, S; Hashimoto, M; Oashi, K; Saikai, T; Suzuki, K; Tanaka, H; Tanaka, S; Teramoto, S1
Inomata, K; Tanaka, H1
Higashikuni, Y; Nagai, R; Sata, M1
Ishikawa, A; Kawabe, K; Kitamura, T; Ohta, N; Ozono, S1
Hayashi, T; Horimoto, H; Inamoto, S; Kitaura, Y; Mieno, S; Mori, T; Okabe, M; Okuda, N1
Fujikawa, K; Hasebe, N; Kikuchi, K1
Hasebe, N1
An, SJ; Choi, JH; Choi, KD; Kim, HJ; Kim, JS; Lee, JE1
Hayashi, K; Ishiguro, K; Itoh, H; Sakamaki, Y; Sasamura, H1
Ando, C; Inoue, Y; Kodama, S; Mihara, H; Miyoshi, K; Niimura, H; Okamura, K; Sumi, S; Tojyo, H; Tsuchiya, Y; Urata, H; Yamanouchi, Y1
Katayama, A; Makino, H; Matsumoto, Y; Nasu, Y; Otsuka, F; Tanabe, K; Tsukamoto, N; Yamanaka, R1
Chinda, J; Fujino, T; Hasebe, N; Kabara, M; Kikuchi, K; Matsuki, M; Nakagawa, N1
Li, H; Liu, X; Wang, S; Yu, H; Zhao, G1
Brendel, E; Dietrich, H; Froede, C; Thomas, D; Weimann, B1
Farinde, A1
Djuric, D; Funke, A; Just, S; Khinast, J; Kleinebudde, P; Knop, K; Scharrer, G; Toschkoff, G1
Charchar, FJ; Harrap, SB1
Itoh, H; Julius, S; Murakami, M; Nakaya, H; Ryuzaki, M; Sasamura, H; Sato, Y; Takahashi, F; Takeuchi, M; Tomotsugu, N1
Cha, G; Gil-Extremera, B; Haller, H; Harvey, P; Heyvaert, F; Kjeldsen, SE; Lewin, AJ; Mancia, G; Sica, D; Villa, G1
Okada, J; Okada, S; Saito, T; Satoh, T; Shibusawa, R; Shimoda, Y; Tagaya, Y; Yamada, E; Yamada, M1
Damen, CW; González, O; Hankemeier, T; van der Kloet, FM; van Vliet, M; Vreeken, RJ1
Goto, M; Hasebe, N; Takahashi, F; Wada, Y1
Cha, G; Gil-Extremera, B; Harvey, P; Kjeldsen, SE; Lewin, AJ; Mancia, G; Villa, G1
Hoshide, S; Kario, K; Mizuno, H; Tomitani, N1
Hirata, T; Ishii, T; Kokuba, S; Nakamura, K; Shiohira, H; Tayag, JCS1

Reviews

2 review(s) available for nifedipine and candesartan

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[NICE-Combi study: effect of nifedipine in combination with an angiotensin II receptor blocker on BP control and renal protection].
    Drugs, 2006, Volume: 66 Spec No 1

    Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Nifedipine; Randomized Controlled Trials as Topic; Tetrazoles

2006

Trials

10 trial(s) available for nifedipine and candesartan

ArticleYear
Effects of candesartan on cough and bronchial hyperresponsiveness in mildly to moderately hypertensive patients with symptomatic asthma.
    Circulation, 2001, Jul-17, Volume: 104, Issue:3

    Topics: Adult; Aged; Antihypertensive Agents; Asthma; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Bronchial Hyperreactivity; Calcium Channel Blockers; Cough; Dihydropyridines; Female; Genetic Testing; Humans; Hypertension; Incidence; Male; Methacholine Chloride; Middle Aged; Nifedipine; Nitrobenzenes; Pain Measurement; Peptidyl-Dipeptidase A; Piperazines; Polymorphism, Genetic; Respiratory Function Tests; Tetrazoles; Treatment Outcome

2001
Inhibition of plasminogen activator inhibitor-1 by angiotensin II receptor blockers on cyclosporine-treated renal allograft recipients.
    Transplantation proceedings, 2005, Volume: 37, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Creatinine; Cyclosporine; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Transplantation; Losartan; Male; Middle Aged; Nifedipine; Plasminogen Activator Inhibitor 1; Tetrazoles; Transplantation, Homologous

2005
Cost-effectiveness analysis of hypertension treatment: controlled release nifedipine and candesartan low-dose combination therapy in patients with essential hypertension--the Nifedipine and Candesartan Combination (NICE-Combi) Study.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:7

    Topics: Adult; Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Cost-Benefit Analysis; Delayed-Action Preparations; Drug Costs; Drug Therapy, Combination; Humans; Hypertension; Japan; Male; Middle Aged; National Health Programs; Nifedipine; Tetrazoles

2005
Additive antihypertensive and antihypertrophic effects of long-acting Ca blockers in uncontrolled hypertensive patients with angiotensin-receptor blocker based treatment.
    International heart journal, 2009, Volume: 50, Issue:5

    Topics: Aged; Amlodipine; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Nifedipine; Tetrazoles

2009
Angiotensin II receptor blocker and long-acting calcium channel blocker combination therapy decreases urinary albumin excretion while maintaining glomerular filtration rate.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Humans; Hypertension, Renal; Male; Middle Aged; Nifedipine; Risk Factors; Tetrazoles; Treatment Outcome; Young Adult

2011
Investigation of bioequivalence of a new fixed-dose combination of nifedipine and candesartan with the corresponding loose combination as well as the drug-drug interaction potential between both drugs under fasting conditions.
    International journal of clinical pharmacology and therapeutics, 2013, Volume: 51, Issue:9

    Topics: Angiotensin II Type 1 Receptor Blockers; Area Under Curve; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Cross-Over Studies; Drug Interactions; Drug Therapy, Combination; Humans; Male; Nifedipine; Tetrazoles; Therapeutic Equivalency

2013
Feasibility of regression of hypertension using contemporary antihypertensive agents.
    American journal of hypertension, 2013, Volume: 26, Issue:12

    Topics: Adult; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Pressure Determination; Double-Blind Method; Drug Administration Schedule; Feasibility Studies; Female; Follow-Up Studies; Humans; Hypertension; Japan; Kaplan-Meier Estimate; Male; Middle Aged; Nifedipine; Prospective Studies; Tetrazoles; Treatment Outcome

2013
Nifedipine plus candesartan combination increases blood pressure control regardless of race and improves the side effect profile: DISTINCT randomized trial results.
    Journal of hypertension, 2014, Volume: 32, Issue:12

    Topics: Administration, Oral; Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Ethnicity; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Tetrazoles; Treatment Outcome

2014
Blood pressure-lowering effects of nifedipine/candesartan combinations in high-risk individuals: subgroup analysis of the DISTINCT randomised trial.
    Journal of human hypertension, 2017, Volume: 31, Issue:3

    Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Tetrazoles

2017
Comparison of ambulatory blood pressure-lowering effects of higher doses of different calcium antagonists in uncontrolled hypertension: the Calcium Antagonist Controlled-Release High-Dose Therapy in Uncontrolled Refractory Hypertensive Patients (CARILLON)
    Blood pressure, 2017, Volume: 26, Issue:5

    Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium; Calcium Channel Blockers; Delayed-Action Preparations; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Prospective Studies; Tetrazoles

2017

Other Studies

18 other study(ies) available for nifedipine and candesartan

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Protective effect of benidipine against sodium azide-induced cell death in cultured neonatal rat cardiac myocytes.
    Journal of pharmacological sciences, 2003, Volume: 93, Issue:2

    Topics: Adenosine Triphosphate; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Captopril; Cell Death; Cells, Cultured; Cysteine Proteinase Inhibitors; Dihydropyridines; Dipeptides; Dose-Response Relationship, Drug; In Vitro Techniques; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria, Muscle; Myocytes, Cardiac; Nifedipine; Rats; Rats, Sprague-Dawley; Sodium Azide; Tetrazoles

2003
Reversible left ventricular hypertrophy after tako-tsubo-like cardiomyopathy.
    Acta cardiologica, 2005, Volume: 60, Issue:1

    Topics: Aged; Aspirin; Benzimidazoles; Biphenyl Compounds; Cardiomyopathy, Dilated; Chest Pain; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Humans; Hypertrophy, Left Ventricular; Magnetic Resonance Imaging; Myocardial Ischemia; Nifedipine; Risk Assessment; Severity of Illness Index; Tetrazoles; Ventricular Dysfunction, Left

2005
Nifedipine enhances the cardioprotective effect of an angiotensin-II receptor blocker in an experimental animal model of heart failure.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Body Weight; Calcium Channel Blockers; Capillaries; Cardiotonic Agents; Coronary Circulation; Disease Models, Animal; Drug Synergism; Heart Failure; Hypertension; Male; Microscopy, Electron; Myocardium; Nifedipine; Organ Size; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tetrazoles; Thiobarbituric Acid Reactive Substances; Ventricular Pressure

2005
Simultaneous posterior ischemic optic neuropathy, cerebral border zone infarction, and spinal cord infarction after correction of malignant hypertension.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2008, Volume: 28, Issue:3

    Topics: Adult; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Brain; Brain Stem Infarctions; Cerebral Infarction; Disease Progression; Female; Fosinopril; Humans; Hydralazine; Hypertension, Malignant; Hypotension; Iatrogenic Disease; Magnetic Resonance Imaging; Nifedipine; Optic Neuropathy, Ischemic; Paraparesis; Spinal Cord; Spinal Cord Ischemia; Tetrazoles; Urinary Incontinence; Vision, Low

2008
"Pulse" treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:1

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Dose-Response Relationship, Drug; Enalapril; Hydralazine; Hypertension; Hypertrophy; Kidney; Male; Matrix Metalloproteinase 13; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Tetrazoles; Vasodilator Agents

2009
Unexpected occurrence of adrenal Cushing's syndrome in a patient with systemic lupus erythematosus.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Angiomyolipoma; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cushing Syndrome; Drug Therapy, Combination; Female; Humans; Hypertension; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Nifedipine; Prednisolone; Ribonucleosides; Spironolactone; Tetrazoles

2011
Candesartan antagonizes pressure overload-evoked cardiac remodeling through Smad7 gene-dependent MMP-9 suppression.
    Gene, 2012, Apr-15, Volume: 497, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Collagen; Epithelial-Mesenchymal Transition; Fibroblasts; Fibronectins; Gene Knockdown Techniques; Heart Ventricles; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Nifedipine; Pressure; rho-Associated Kinases; RNA, Small Interfering; Signal Transduction; Smad3 Protein; Smad7 Protein; Tetrazoles; Transforming Growth Factor beta1; Up-Regulation; Ventricular Remodeling

2012
Drugs for treating hypertension.
    Nursing, 2013, Volume: 43, Issue:8

    Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drugs, Generic; Humans; Hydrochlorothiazide; Hypertension; Nifedipine; Prescription Drugs; Ramipril; Tetrazoles

2013
Optimization of the inter-tablet coating uniformity for an active coating process at lab and pilot scale.
    International journal of pharmaceutics, 2013, Nov-30, Volume: 457, Issue:1

    Topics: Benzimidazoles; Biphenyl Compounds; Drug Compounding; Nifedipine; Tablets; Tetrazoles

2013
Early treatment to prevent hypertension: a laudable goal.
    American journal of hypertension, 2013, Volume: 26, Issue:12

    Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Female; Humans; Hypertension; Male; Nifedipine; Tetrazoles

2013
Glycosuria medicated with ipragliflozin and nifedipine or ipragliflozin and candesartan: a case report.
    Journal of medical case reports, 2014, Dec-16, Volume: 8

    Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Drug Therapy, Combination; Glucosides; Glycosuria; Humans; Male; Middle Aged; Nifedipine; Tetrazoles; Thiophenes; Treatment Outcome

2014
Matrix Effect Compensation in Small-Molecule Profiling for an LC-TOF Platform Using Multicomponent Postcolumn Infusion.
    Analytical chemistry, 2015, Jun-16, Volume: 87, Issue:12

    Topics: Acetaminophen; Benzimidazoles; Benzoates; Biphenyl Compounds; Chromatography, High Pressure Liquid; Clomipramine; Dihydropyridines; Enkephalin, Leucine; Humans; Mass Spectrometry; Nifedipine; Pharmaceutical Preparations; Simvastatin; Telmisartan; Tetrazoles; Time Factors

2015
Successful Treatment with an Antihypertensive Drug Regimen Including Eplerenone in a Patient with Malignant Phase Hypertension with Renal Failure.
    Internal medicine (Tokyo, Japan), 2015, Volume: 54, Issue:19

    Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Creatinine; Drug Therapy, Combination; Eplerenone; Heart Failure; Humans; Hypertension, Malignant; Male; Nifedipine; Nitroglycerin; Obesity; Renal Insufficiency; Spironolactone; Tetrazoles; Treatment Outcome; Vasodilator Agents

2015
Effects of 5-fluorouracil Co-administration on Blood Pressure in Patients Maintained on Antihypertensives: a Retrospective Case Series.
    Die Pharmazie, 2023, 05-01, Volume: 78, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Antineoplastic Agents; Blood Pressure; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Fluorouracil; Humans; Hypertension; Nifedipine; Retrospective Studies; Tetrazoles; Valine; Valsartan

2023