nifedipine has been researched along with caffeine in 228 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (16.23) | 18.7374 |
| 1990's | 90 (39.47) | 18.2507 |
| 2000's | 70 (30.70) | 29.6817 |
| 2010's | 29 (12.72) | 24.3611 |
| 2020's | 2 (0.88) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Belas, F; Chaudhary, AK; Cvetkovic, M; Dempsey, PJ; Fromm, MF; Kim, RB; Leake, B; Roden, DM; Roden, MM; Wandel, C; Wilkinson, GR; Wood, AJ | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Sen, S; Sinha, N | 1 |
| Arce, MP; Conde, S; del Barrio, L; Egea, J; García, AG; González-Muñoz, GC; León, R; López, B; López, MG; Martín-de-Saavedra, MD; Pérez, C; Rodríguez-Franco, MI; Romero, A; Villarroya, M | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN | 1 |
| Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF | 1 |
| Fleckenstein, A; Grün, G | 1 |
| Huang, LJ; Huang, TF; Kuo, SC; Sun, SS; Teng, CM; Yu, SM | 1 |
| Ito, S; Ohga, A; Ohta, T | 1 |
| Bishopric, NH; Sato, B; Webster, KA | 1 |
| Deitmer, P; Lammel, E; Noack, T | 1 |
| Kuramoto, K; Nishimura, S; Sorimachi, M; Yamagami, K | 1 |
| Bose, D; Bouchard, RA | 1 |
| Schouten, VJ; ter Keurs, HE | 1 |
| Kocsis, JD; O'Regan, MH; Waxman, SG | 1 |
| Holland, M; Lee, JC; McGrath, CJ; Ward, CW; Williams, JH | 1 |
| Davy, KP; Holland, M; Lee, JC; Ward, CW; Williams, JH | 1 |
| Fukuda, Y; Inukai, T; Kuroda, K; Nakao, K | 1 |
| Brading, AF; Parekh, AB | 1 |
| Carlos, AD; Ikemoto, N; Kang, JJ; Ohkusa, T; Smilowitz, H | 1 |
| Fabrègues, E; John, GW; Kamal, M; Massingham, R | 1 |
| Henschel, L; Hoffmann, A; Sigusch, H | 1 |
| Brandt, J; Ernst, R; Mumme, A; Schäfer, K; Zumtobel, V | 1 |
| Lennard, MS; Loft, S; Otton, SV; Poulsen, HE; Tucker, GT | 1 |
| Benders, AA; Jacobs, AE; Joosten, EG; Oosterhof, A; Veerkamp, JH; Wevers, RA | 1 |
| Amobi, N; Smith, IC | 1 |
| Røed, A | 1 |
| Bridge, JH; Smolley, JR; Spitzer, KW | 1 |
| Fletcher, JE; Huggins, FJ; Rosenberg, H | 1 |
| Auclair, MC; Lechat, P; Vernimmen, C | 1 |
| Hwang, KS; Van Breemen, C | 1 |
| Bers, DM; MacLeod, KT | 1 |
| Dryden, WF; Singh, YN | 1 |
| Ito, M; Morikawa, M; Satake, N; Shibata, S | 1 |
| Barbanti, G; Giachetti, A; Giuliani, S; Maggi, CA; Meli, A; Patacchini, R; Turini, D | 1 |
| Cooper, SM; Wilson, C | 1 |
| Aaronson, PI; Benham, CD | 1 |
| Cabanie, M; Ebeigbe, AB; Godfraind, T | 1 |
| Imai, S; Matsui, K; Ogawa, Y | 1 |
| Itoh, T; Kuriyama, H; Ueno, H | 1 |
| Maggi, CA; Manzini, S; Meli, A | 1 |
| Green, CL; Swanson, TH | 1 |
| Fujiwara, T; Ishimatsu, T; Itoh, T; Kanmura, Y; Satoh, S | 1 |
| Myers, MG; van Nguyen, P | 1 |
| Kuriyama, H; Sumimoto, K | 1 |
| Hester, RK; Satake, N; Shibata, S; Tomiyama, A; Ueda, S; Wakabayashi, S | 1 |
| Castellucci, A; Franconi, F; Giotti, A; Manzini, S | 1 |
| Rahwan, RG; Wong, WS | 1 |
| Bers, DM; Christensen, DM; Nguyen, TX | 1 |
| Benedetti, M; Frank, C; Sagratella, S; Scotti de Carolis, A | 1 |
| Burdyga, TV; Magura, IS | 1 |
| Itoh, T; Kubota, Y; Kuriyama, H; Satoh, S | 1 |
| Davis, C; Kannan, L; Kannan, MS; Ladenius, AR | 1 |
| Astolfi, M; Maggi, CA; Manzini, S; Meli, A; Parlani, M | 1 |
| Walland, A | 1 |
| Itoh, T; Kanmura, Y; Kuriyama, H | 1 |
| Imai, S; Nabata, H; Nakazawa, M; Sakai, K; Ushijima, T | 1 |
| Lin, CI; Lin, KY; Lu, HH | 1 |
| Khodorov, BI; Khodorova, AB; Mukumov, MR | 1 |
| Auclair, MC; Carli, A; Vernimmen, C | 1 |
| Itoh, T; Kanmura, Y; Kuriyama, H; Suzuki, H | 1 |
| Auclair, MC; Vernimmen, C | 1 |
| Dagher, FJ; Kemerer, VF; Pais, SO | 1 |
| Dehpour, AR; Mahmoudian, M; Mofakham, S | 1 |
| Chapunoff, D; Herman, CA; Romero, MA; Schulmeister, K; Skarda, S; Torres, OA | 1 |
| Ogihara, M | 1 |
| Ito, S; Kitamura, N; Nakazato, Y; Ohta, T | 1 |
| Hidalgo, J; Jaimovich, E; Niemeyer, MI | 1 |
| Jino, H; Kurahashi, K; Nakata, Y; Shimizu, Y; Shirahase, H; Usui, H | 1 |
| Denborough, MA; Foster, PS | 1 |
| Cognard, C; Constantin, B; Raymond, G; Rivet-Bastide, M | 1 |
| Ko, FN; Lu, ST; Teng, CM; Wu, YC | 1 |
| Alexander, PB; Cheung, DW | 1 |
| Luxoro, M; Nassar-Gentina, V; Rojas, E | 1 |
| Austin, C; Taggart, MJ; Wray, S | 1 |
| Drescher, P; Eckert, R; Madsen, PO; Sparwasser, C | 1 |
| Rhoten, WB; Sergeev, IN | 1 |
| Chen, X; Lange, AB; Orchard, I; Wang, Z | 1 |
| D'Ocon, MP; Noguera, MA | 1 |
| Bennett, MR; Larkum, ME; Warren, DA | 1 |
| Hatano, Y; Kakuyama, M; Mori, K; Nakamura, K; Nishiwada, M; Terasako, K; Toda, H | 1 |
| Brading, AF; Nakayama, S | 1 |
| Clausen, C; Goligorsky, MS; Gordienko, DV | 1 |
| Bhatnagar, A; Castro, GJ | 1 |
| Goldman, WF; Salvaterra, CG | 1 |
| Dunlop, W; Gillespie, JI; Greenwell, JR; Otun, H | 1 |
| Garcia, L; Marty, I; Parrish, E; Rieger, F; Romey, G; Seigneurin-Venin, S; Villaz, M | 1 |
| Criddle, DN; de Moura, RS; Jazbik, W | 1 |
| Ho, KC; Lin, PS; Yang, SJ | 1 |
| Fried, G; Liu, YA; Ostlund, E | 1 |
| Gelband, CH; Martens, JR; Posner, P; Sumners, C; Wang, D | 1 |
| Asano, M; Imaizumi, Y; Ito, K; Ito, KM; Kuwako, M; Nomura, Y; Uyama, Y; Watanabe, M | 1 |
| Frosini, M; Plami, M; Sgaragli, G | 1 |
| Burdyga, TV; Taggart, MJ; Wray, S | 1 |
| Kamberov, ES; Kristev, A; Roussev, GK; Trifonov, BB | 1 |
| Blatter, LA; Holda, JR; Oberti, C; Perez-Reyes, E | 1 |
| Kang, BS; Lee, EY; Lee, HY; Lee, YH | 1 |
| Caglayan, B; Eroglu, L; Tuna, R | 1 |
| Asano, M; Ito, K; Kuwako, M; Nomura, Y; Shibuya, M; Sugita, K; Suzuki, Y | 1 |
| Beurg, M; Coronado, R; Gregg, RG; Powers, PA; Strube, C | 1 |
| MacLeod, KT; Terracciano, CM | 1 |
| Kanmura, Y; Yamaguchi, S; Yoshimura, N | 1 |
| Gould, DJ; Hill, CE | 1 |
| Aoki, T; Koshita, M; Oba, T; Yamaguchi, M | 1 |
| Bone, Q; Inoue, I; Tsutsui, I | 1 |
| Hiruma, T; Komazaki, S | 1 |
| Guibert, C; Marthan, R; Savineau, JP | 1 |
| Bendhack, LM; Tostes, RC; Webb, RC; Wilde, DW | 1 |
| Bielefeldt, K; Conklin, JL; Martin, M; Oh, ST; Yedidag, E | 1 |
| Costa, G; García-Pascual, A; Jimenez, E; Labadía, A; Triguero, D | 1 |
| Huang, YH; Liu, KS; Wang, SQ; Zhou, ZQ | 1 |
| Jiao, Y; Preiksaitis, HG; Sims, SM | 1 |
| Cotton, KD; Hollywood, MA; McHale, NG; Thornbury, KD | 1 |
| Hussain, M; Orchard, CH | 1 |
| Vornanen, M | 1 |
| Bkaily, G; D'Orléans-Juste, P; Economos, D; Jaalouk, D; Jacques, D; Naik, R; Pothier, P | 1 |
| Drescher, P; Eckert, R; Madsen, PO; Schmelz, HU; Sparwasser, C | 1 |
| Han, C; Kwan, CY; Zhu, WZ | 1 |
| Amobi, NI; Smith, IC | 2 |
| Bennett, MR; Brain, KL; Lin, YQ | 1 |
| Boev, KK; Petkov, GV | 1 |
| Edwards, FR; Hashitani, H | 1 |
| Dickens, EJ; Hirst, GD; Tomita, T | 1 |
| Asano, M; Nomura, Y | 1 |
| Bramich, NJ; Hirst, GD | 1 |
| Chaban, VV; Dea, SK; Ennes, HS; Mayer, EA; McRoberts, JA; Young, SH | 1 |
| Peers, C; Taylor, SC | 1 |
| Bendhack, LM; Callera, GE | 1 |
| Cocks, TM; Selemidis, S | 1 |
| Constanti, A; Libri, V; Postlethwaite, M | 1 |
| Dosen, PJ; Imtiaz, MS; Nurgaliyeva, K; van Helden, DF; von der Weid, P | 1 |
| Bramich, NJ; Hashitani, H; Hirst, GD | 1 |
| Aaronson, PI; Hague, D; Robertson, TP; Ward, JP | 1 |
| Dora, KA; Garland, CJ; Hill, PB; Hughes, AD | 1 |
| Furuya, K; Kato, K; Ozaki, T; Tsutsui, I; Yamagishi, S | 1 |
| Hove-Madsen, L; Llach, A; Tort, L | 1 |
| Fernandez Pereira, SP; Giestal de Araujo, E | 1 |
| Atkins, CM; Li, YP; Reid, MB; Sweatt, JD | 1 |
| Coats, P; Hillier, C; Johnston, F; MacDonald, J; McMurray, JJ | 1 |
| Hollywood, MA; McCloskey, KD; McHale, NG; Sergeant, GP; Thornbury, KD | 1 |
| Reznikov, VL; Shuba, MF | 1 |
| Curtis, TM; Scholfield, CN | 1 |
| Chawla, S; Hockaday, AR; Huang, CL; Skepper, JN | 1 |
| Efimov, A; Kostyuk, E; Kostyuk, P; Kruglikov, I; Shishkin, V; Shmigol, A; Voitenko, N | 1 |
| Mawe, GM; Nelson, MT; Pérez, GJ; Pozo, MJ | 1 |
| Ebihara, Y; Gen, W; Takeshita, J; Tamaki, K; Tani, M | 1 |
| Florea, S; Raicu, M | 1 |
| Mitra, P; Slaughter, MM | 1 |
| Bedfer, G; Le Guennec, JY; Vandier, C | 1 |
| Hanano, T; Inoue, R; Ito, Y; Itonaga, Y; Miyauchi, Y; Morita, H; Nakajima, T | 1 |
| Liang, JH; Liu, RK; Sun, HL; Wang, XH; Ye, XF; Zheng, JW | 1 |
| Imtiaz, MS; van Helden, DF | 1 |
| Burt, RP | 1 |
| Dierkes, PW; Hochstrate, P; Schlue, WR; Schoppe, J | 1 |
| Bigdai, EV; Samoilov, VO | 1 |
| Gscheidlinger, R; Hohenegger, M; Karel, A; Weigl, L; Zidar, A | 1 |
| Hayashi, K; Ohno, Y; Saruta, T; Suzuki, H; Takenaka, T | 1 |
| Boron, WF; Bouyer, P; Zhou, Y | 1 |
| Allen, PD; Kim, DH; Lee, EH; Li, J; Lopez, JR; Pessah, IN; Protasi, F | 1 |
| Paterson, WG; Zhang, Y | 1 |
| Marcel, KN; Moreland, RS; Smolock, EM; Su, X | 1 |
| Cheek, ER; Fast, VG; Ideker, RE; Pollard, AE | 1 |
| Aoyama, M; Chen, SR; Furuzono, S; Goto, T; Hotta, S; Imaizumi, Y; Ito, Y; Matsubara, T; Nakayama, S; Ohya, S; Shimokata, K; Wang, J; Yamada, A | 1 |
| Dierkes, PW; Hochstrate, P; Schlue, WR; Wende, V | 1 |
| Arruebo, MP; Grasa, L; Murillo, MD; Plaza, MA; Rebollar, E | 1 |
| Huang, XL; Pan, BX; Zhao, GL; Zhao, KS | 1 |
| Kito, Y; Sanders, KM; Ward, SM | 1 |
| Imaizumi, Y; Liu, HN; Nakayama, S; Ohya, S; Wang, J | 1 |
| Shinozaki, T; ter Keurs, HE; Wilkens, JL; Yazawa, T | 1 |
| Currie, S; Hasenfuss, G; Kettlewell, S; Loughrey, CM; Miller, SL; Reynolds, DF; Seidler, T; Smith, GL | 1 |
| Balasubramaniam, R; Chawla, S; Grace, AA; Huang, CL | 1 |
| Perez, JF; Sanderson, MJ | 1 |
| Huang, Z; Ishii, Y; Liu, H; Miyake, S; Suzaki, T; Tsuchiya, T; Watari, T | 1 |
| Dai, JM; Kuo, KH; Lee, CH; Leo, JM; van Breemen, C | 1 |
| Willows, AO; Woodward, OM | 1 |
| Bulaeva, SV; Chuchkanov, FA; Maimistova, AA; Muravyov, AV; Yakusevich, VV; Zaitsev, LG | 1 |
| Sims, SM; Williams, BA | 1 |
| Jin, CM; Kim, YM; Lee, JJ; Lee, MK; Park, SK; Yang, YJ; Yin, SY; Yoo, SK | 1 |
| Hatton, WJ; Hume, JR; Kyle, BD; Lennox, AR; Ng, LC; Shen, XM | 1 |
| Chen, JN; John, SA; Ottolia, M; Philipson, KD; Xie, Y | 1 |
| Horvath, B; Kesmarky, G; Toth, K; Vekasi, J | 1 |
| Adhikari, A; da Costa, JL; Kihara, AH; Lorençon, E; Resende, RR | 1 |
| Benotti, MJ; Brownawell, BJ | 1 |
| Grace, AA; Huang, CL; Killeen, MJ; Lei, M; Ma, A; Schwiening, C; Zhang, Y | 1 |
| Adaramoye, OA; Almeida, MM; Anjos, RM; Araújo, IG; Cavalcante, KV; Medeiros, IA; Oliveira, AP; Oliveira, FA; Silvia, DF; Veras, RC | 1 |
| Döndaş, NY; Kaplan, M; Kaya, D; Singirik, E | 1 |
| Fraser, JA; Grace, AA; Huang, CL; Killeen, MJ; Schwiening, C; Zhang, Y | 1 |
| Baptista, BB; Farah, LS; Granado e Sá, M; Leite, VP; Zanotto, FP | 1 |
| Burdyga, T; Prendergast, C; Quayle, J; Wray, S | 1 |
| Asano, Y; Ishida, H; Ishiwata, T; Kanai, T; Kawamura, Y; Kurokawa, T; Nishiyama, M; Nonoyama, S; Takizawa, M | 1 |
| Falck, JR; Jacobs, ER; Li, J; Li, W; Liu, Y; Manthati, VL; Medhora, M; Rao, J; Wang, R; Zhu, D | 1 |
| Bougoin, S; Brotto, LS; Brotto, M; Hardin, B; Ma, J; Nosek, TM; Pan, Z; Parness, J; Reid, M; Thornton, AM; Weisleder, N; Zhao, X | 1 |
| Mimura, H; Nasu, M; Nemoto, T; Sako, K | 1 |
| Arranz-Tagarro, JA; Calvo-Gallardo, E; de Pascual, R; Fernández-Morales, JC; Gandía, L; García, AG; Olivares, R; Padín, JF; Vestring, S | 1 |
| Bootman, MD; Rietdorf, K; Sanderson, MJ | 1 |
| Barreda, DR; Chang, JP; Davis, PJ; Pemberton, JG; Rieger, AM; Sawisky, GR | 1 |
| Borysova, L; Burdyga, T; Noble, D; Wray, S | 1 |
| Aalto-Setälä, K; Baba, S; Balijepalli, S; Conklin, BR; Fu, CC; Hayashi, Y; Healy, KE; Hua, EA; January, CT; Kamp, TJ; Lizarraga, P; Makielski, JC; Nakamura, K; Scheinman, MM; Sears, MA; Spencer, CI; Tomoda, K; Wojciak, J; Yamanaka, S; Zhang, J | 1 |
| Alashi, Y; Biliaminu, SA; Owoyele, BV; Oyewole, AL | 1 |
| Coboeken, K; Dallmann, A; Eissing, T; Hempel, G; Ince, I | 1 |
| Baker, SA; Cobine, CA; Drumm, BT; Hannigan, KI; Koh, SD; Lee, JY; Rembetski, BE; Sanders, KM | 1 |
4 review(s) available for nifedipine and caffeine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells | 2022 |
Calcium-induced calcium release mechanism in vascular smooth muscles--assessments based on contractions evoked in intact and saponin-treated skinned muscles.
Topics: Animals; Caffeine; Calcium; Cell Membrane Permeability; Cells, Cultured; Cyclic AMP; Glycerol; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nisoldipine; Phosphatidylinositols; Polyenes; Polyethylene Glycols; Procaine; Receptors, Cell Surface | 1985 |
Nifedipine: more than a calcium channel blocker.
Topics: Adenosine; Animals; Benzodiazepines; Biological Transport; Caffeine; Coronary Disease; Humans; Nifedipine; Receptors, Cell Surface; Receptors, Purinergic | 1986 |
1 trial(s) available for nifedipine and caffeine
| Article | Year |
|---|---|
Cardiovascular effects of caffeine and nifedipine.
Topics: Adult; Blood Pressure; Caffeine; Clinical Trials as Topic; Double-Blind Method; Heart Rate; Humans; Male; Nifedipine; Random Allocation | 1988 |
223 other study(ies) available for nifedipine and caffeine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Resistance, Multiple; Enzyme Inhibitors; Humans; Male; Mice; Oxidoreductases, N-Demethylating; Pharmacokinetics; Substrate Specificity | 1999 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogPoct: a tool for lipophilicity determination in drug discovery.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cell Death; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Okadaic Acid; Peptide Fragments; Phenothiazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.
Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain | 2016 |
[Calcium-antagonism, a new principle in coronary vasodilation].
Topics: Animals; Caffeine; Calcium; Cardiac Glycosides; Chromonar; Coronary Vessels; Muscle Tonus; Muscle, Smooth; Nifedipine; Nitrites; Nitroglycerin; Papaverine; Prenylamine; Swine; Vasodilator Agents; Verapamil | 1975 |
Vasorelaxation of rat thoracic aorta caused by two Ca(2+)-channel blockers, HA-22 and HA-23.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Caffeine; Calcium Channel Blockers; Cromakalim; Cyclic AMP; Cyclic GMP; Female; In Vitro Techniques; Male; Nifedipine; Pyrans; Pyrazoles; Pyrroles; Rats; Rats, Inbred Strains; Vasodilation; Verapamil | 1992 |
Effects of vasoactive intestinal peptide (VIP) on contractile responses of smooth muscle in rat stomach.
Topics: Animals; Caffeine; Calcium; Carbachol; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium Chloride; Rats; Rats, Wistar; Stomach; Vasoactive Intestinal Peptide | 1991 |
Beta-adrenergic regulation of a myocardial actin gene via a cyclic AMP-independent pathway.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Actins; Animals; Animals, Newborn; Blotting, Northern; Bucladesine; Caffeine; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Enkephalins; Gene Expression Regulation; Heart; Heart Ventricles; Isoproterenol; Kinetics; Myocardium; Nifedipine; Potassium Chloride; Propranolol; Protein Precursors; Rats; Receptors, Adrenergic, beta; RNA; RNA, Messenger; Ryanodine | 1992 |
Characterization of membrane currents in single smooth muscle cells from the guinea-pig gastric antrum.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Animals; Caffeine; Calcium; Guinea Pigs; In Vitro Techniques; Kinetics; Membrane Potentials; Muscle, Smooth; Nifedipine; Potassium; Pyloric Antrum; Tetraethylammonium; Tetraethylammonium Compounds | 1992 |
Possible regulation of caffeine-induced intracellular Ca2+ mobilization by intracellular free Na+.
Topics: Animals; Biological Transport; Caffeine; Calcium; Cats; Cells, Cultured; Chromaffin System; Cytophotometry; Magnesium; Nifedipine; Ryanodine; Sodium | 1992 |
Contribution of sarcolemmal sodium-calcium exchange and intracellular calcium release to force development in isolated canine ventricular muscle.
Topics: Animals; Biological Transport; Caffeine; Calcium; Carrier Proteins; Dogs; Heart Ventricles; Intracellular Membranes; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Ryanodine; Sarcolemma; Sodium; Sodium-Calcium Exchanger; Time Factors; Ventricular Function | 1992 |
Role of Ica and Na+/Ca2+ exchange in the force-frequency relationship of rat heart muscle.
Topics: Action Potentials; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Diastole; Electric Stimulation; Heart; Myocardial Contraction; Myocardium; Nifedipine; Rats; Sarcolemma; Sodium; Time Factors | 1991 |
Depolarization-dependent actions of dihydropyridines on synaptic transmission in the in vitro rat hippocampus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Dihydropyridines; Evoked Potentials; Female; Hippocampus; In Vitro Techniques; Light; Membrane Potentials; Neurons; Nifedipine; Nimodipine; Perfusion; Potassium; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission | 1990 |
BAY K 8644 and nifedipine alter halothane but not caffeine contractures of malignant hyperthermic muscle fibers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Halothane; Malignant Hyperthermia; Muscle Contraction; Muscles; Nifedipine; Swine | 1991 |
Effects of BAY K 8644, nifedipine, and low Ca2+ on halothane and caffeine potentiation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Drug Synergism; Halothane; In Vitro Techniques; Muscle Contraction; Muscles; Nifedipine; Swine | 1991 |
Effects of felodipine on vascular smooth muscle in comparison with nifedipine.
Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Felodipine; Femoral Artery; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Sarcolemma | 1991 |
The sources of calcium for carbachol-induced contraction in the circular smooth muscle of guinea-pig stomach.
Topics: Animals; Biopolymers; Caffeine; Calcium; Carbachol; Female; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Nifedipine; Procaine; Stomach | 1991 |
Effects of dihydropyridines on calcium release from the isolated membrane complex consisting of the transverse tubule and sarcoplasmic reticulum.
Topics: Animals; Caffeine; Calcium; Calcium Channels; Kinetics; Microsomes; Muscles; Nifedipine; Nimodipine; Rabbits; Receptors, Nicotinic; Sarcoplasmic Reticulum | 1991 |
Caffeine-induced contractions in rabbit isolated renal artery are differentially inhibited by calcium antagonists.
Topics: Animals; Bepridil; Caffeine; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Fendiline; Flunarizine; Kinetics; Lidoflazine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Rabbits; Renal Artery; Verapamil | 1991 |
[The effects of verapamil and nifedipine on the biotransformation of model substances and on the indocyanine green elimination].
Topics: Adult; Biotransformation; Caffeine; Debrisoquin; Dipyrone; Humans; Indocyanine Green; Liver; Liver Circulation; Male; Nifedipine; Sulfamethazine; Verapamil | 1991 |
[Extremity-threatening ischemia in ergotism. Successful treatment with the intra-arterial administration of nifedipine].
Topics: Acute Disease; Adult; Arm; Caffeine; Drug Combinations; Ergotamine; Ergotism; Female; Humans; Infusions, Intra-Arterial; Ischemia; Migraine Disorders; Nifedipine; Radiography; Suppositories; Time Factors; Ultrasonography | 1991 |
Characterization of metronidazole metabolism by human liver microsomes.
Topics: Acetone; Adult; Benzoflavones; Caffeine; Cytochrome P-450 Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Kinetics; Male; Mephenytoin; Metronidazole; Microsomes, Liver; Middle Aged; Nifedipine; Phenacetin; Quinidine; Theophylline; Tolbutamide | 1991 |
Effect of various agents on the cytoplasmic calcium concentration in cultured human muscle cells.
Topics: Acetylcholine; Adolescent; Adult; Aminoquinolines; Caffeine; Calcium; Cells, Cultured; Cytoplasm; Dantrolene; Electric Conductivity; Fluorescent Dyes; Humans; Middle Aged; Muscles; Nifedipine | 1991 |
Paradoxical effects of thioridazine on electromechanical coupling in the human and rat vas deferens.
Topics: Animals; Biomechanical Phenomena; Caffeine; Calcimycin; Calcium Channel Blockers; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Rats; Thioridazine; Vas Deferens; Verapamil | 1991 |
Selective potentiation of subtetanic and tetanic contractions by the calcium-channel antagonist nifedipine in the rat diaphragm preparation.
Topics: Animals; Caffeine; Calcium; Diaphragm; Electric Stimulation; Female; In Vitro Techniques; Male; Membranes; Muscle Contraction; Nifedipine; Phenytoin; Potassium; Quinine; Rats; Rats, Inbred Strains; Respiratory Muscles | 1991 |
The relationship between charge movements associated with ICa and INa-Ca in cardiac myocytes.
Topics: Animals; Caffeine; Calcium; Calcium Channels; Carrier Proteins; Electric Conductivity; Guinea Pigs; Heart; Membrane Potentials; Myocardial Contraction; Myocardium; Nifedipine; Sarcoplasmic Reticulum; Sodium; Sodium-Calcium Exchanger | 1990 |
The importance of calcium ions for in vitro malignant hyperthermia testing.
Topics: Caffeine; Calcium; Contracture; Drug Interactions; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Nifedipine; Quinacrine; Strontium; Succinylcholine; Verapamil | 1990 |
[Effect of substances modifying calcium movement on the contractility of cultured cardiac cells].
Topics: Animals; Caffeine; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Histamine; Imipramine; Ion Channels; Isoproterenol; Myocardial Contraction; Nifedipine; Phenylephrine; Rats; Verapamil | 1985 |
Effects of the Ca agonist Bay K8644 on 45Ca influx and net Ca uptake into rabbit aortic smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Caffeine; Calcium; In Vitro Techniques; Ion Channels; Membrane Potentials; Muscle, Smooth, Vascular; Nifedipine; Potassium; Rabbits | 1985 |
Cumulative depletions of extracellular calcium in rabbit ventricular muscle monitored with calcium-selective microelectrodes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Cobalt; Electric Stimulation; Extracellular Space; Heart; In Vitro Techniques; Microelectrodes; Myocardium; Nifedipine; Rabbits; Ryanodine; Strophanthidin | 1986 |
Sites of action of dihydropyridine drugs in the mouse hemidiaphragm muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Caffeine; Calcium Channel Blockers; Diaphragm; In Vitro Techniques; Ion Channels; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Muscles; Nifedipine; Potassium | 1988 |
Bay K 8644-induced potentiation of the contractile response of rabbit iliac artery to caffeine in a Ca2+-free medium.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Calcium Chloride; Egtazic Acid; Iliac Artery; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Potassium Chloride; Rabbits; Vanadates | 1989 |
Multiple sources of calcium for contraction of the human urinary bladder muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aged; Caffeine; Calcium; Carbachol; Endothelins; Female; Humans; In Vitro Techniques; Lanthanum; Male; Middle Aged; Mollusk Venoms; Muscle Contraction; Neurokinin A; Nickel; Nifedipine; omega-Conotoxins; Peptides; Potassium Chloride; Procaine; Urinary Bladder | 1989 |
Effect of cromakalim on contractions in rabbit isolated renal artery in the presence and absence of extracellular Ca2+.
Topics: Animals; Benzopyrans; Caffeine; Calcium; Calcium Channel Blockers; Cromakalim; Guanidines; Guanylate Cyclase; Histamine; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroprusside; Norepinephrine; Pinacidil; Pyrroles; Rabbits; Renal Artery; Vasodilator Agents | 1989 |
Alterations in [Ca2+]i mediated by sodium-calcium exchange in smooth muscle cells isolated from the guinea-pig ureter.
Topics: Animals; Biological Transport, Active; Caffeine; Calcium; Guinea Pigs; Male; Membrane Potentials; Muscle, Smooth; Nifedipine; Sodium | 1989 |
Effects of cicletanine on histamine-induced contractions of isolated rabbit mesenteric arteries.
Topics: Animals; Anti-Arrhythmia Agents; Caffeine; Calcium; Calcium Radioisotopes; Diuretics; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Pyridines; Rabbits | 1989 |
Relaxant effects of pinacidil, nicorandil, hydralazine and nifedipine as studied in the porcine coronary artery and guinea-pig taenia coli.
Topics: Animals; Caffeine; Colon; Coronary Vessels; Female; Guanidines; Guinea Pigs; Hydralazine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium; Swine; Vasodilator Agents | 1986 |
5-Hydroxytryptamine delays relaxation time of norepinephrine-induced vasoconstriction.
Topics: Animals; Arteries; Bucladesine; Caffeine; Calcium; Desoxycorticosterone; Drug Interactions; Ear; Edetic Acid; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle Relaxation; Nifedipine; Norepinephrine; Rabbits; Serotonin; Sodium Chloride; Sympathectomy, Chemical; Tetraethylammonium; Tetraethylammonium Compounds; Vasoconstriction | 1986 |
Mechanisms of flunarizine-induced vasodilation in the rabbit mesenteric artery.
Topics: Animals; Biomechanical Phenomena; Caffeine; Calcium; Flunarizine; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phosphatidic Acids; Phosphatidylinositols; Potassium; Rabbits; Vasodilation | 1987 |
Mobilization of free Ca2+ measured during contraction-relaxation cycles in smooth muscle cells of the porcine coronary artery using quin2.
Topics: Acetylcholine; Aminoquinolines; Animals; Caffeine; Calcium; Calcium Channel Blockers; Coronary Vessels; Egtazic Acid; Fluorescent Dyes; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nisoldipine; Potassium; Swine | 1986 |
Mode of vasorelaxing action of 5-[3-[[2-(3,4-dimethoxyphenyl)-ethyl]amino]-1-oxopropyl]-2,3,4,5- tetrahydro-1,5-benzothiazepine fumarate (KT-362), a new intracellular calcium antagonist.
Topics: Animals; Caffeine; Calcium Channel Blockers; Diltiazem; Egtazic Acid; Gallopamil; Lanthanum; Male; Methoxamine; Muscle Contraction; Nifedipine; Nitroglycerin; Norepinephrine; Rabbits; Thiazepines; Vasodilation; Verapamil | 1987 |
An analysis of the effects of taurine on cellular and extracellular calcium mobilization in rabbit ear artery.
Topics: Animals; Arteries; beta-Alanine; Caffeine; Calcium; Ear; Extracellular Space; In Vitro Techniques; Male; Nifedipine; Norepinephrine; Potassium; Procaine; Rabbits; Taurine; Vasoconstriction | 1987 |
Pharmacological actions of the calcium antagonist propyl-methylenedioxyindene in skinned vascular smooth muscle.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Indenes; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Inbred Strains; Saponins; Trifluoperazine | 1988 |
Can Ca entry via Na-Ca exchange directly activate cardiac muscle contraction?
Topics: Action Potentials; Animals; Caffeine; Calcium; Carrier Proteins; Heart Ventricles; In Vitro Techniques; Myocardial Contraction; Nifedipine; Rabbits; Ryanodine; Sodium-Calcium Exchanger; Strophanthidin; Ventricular Function | 1988 |
Comparative influence of calcium blocker and purinergic drugs on epileptiform bursting in rat hippocampal slices.
Topics: Adenosine; Animals; Caffeine; Calcium; Epilepsy; Hippocampus; In Vitro Techniques; Magnesium; Male; Neurons; Nifedipine; Phenylisopropyladenosine; Pyramidal Tracts; Rats; Rats, Inbred Strains; Verapamil | 1988 |
Effects of temperature and Na0+ on the relaxation of phasic and tonic tension of guinea-pig ureter muscle.
Topics: Animals; Caffeine; Calcium; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nifedipine; Sodium; Temperature; Ureter; Vanadates | 1988 |
Mechanisms of the Ba2+-induced contraction in smooth muscle cells of the rabbit mesenteric artery.
Topics: Animals; Barium; Biomechanical Phenomena; Caffeine; Calcium; Contractile Proteins; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nisoldipine; Potassium; Rabbits | 1987 |
Agonist interactions at the calcium pools in skinned and unskinned canine tracheal smooth muscle.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Dogs; Female; Histamine; In Vitro Techniques; Isometric Contraction; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium Chloride; Serotonin; Theophylline; Trachea | 1987 |
Positive inotropic effect of Mg2+ in K+-depolarized isoprenaline-reactivated guinea-pig ventricular strip.
Topics: Action Potentials; Animals; Caffeine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Kinetics; Magnesium; Myocardial Contraction; Nifedipine; Potassium; Stimulation, Chemical; Tetrodotoxin | 1986 |
Investigation into the inotropic mechanisms of sulmazole.
Topics: Animals; Caffeine; Calcium; Cardiotonic Agents; Diaphragm; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Ionophores; Male; Muscle Contraction; Myocardial Contraction; Myocardium; Nifedipine; Rats; Sodium | 1985 |
Agonist actions of Bay K 8644, a dihydropyridine derivative, on the voltage-dependent calcium influx in smooth muscle cells of the rabbit mesenteric artery.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Female; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium; Rabbits; Saponins | 1984 |
Mechanism of relaxant effects of nicorandil on the dog coronary artery.
Topics: Animals; Caffeine; Calcium; Coronary Vessels; Dogs; Female; Lanthanum; Male; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Potassium; Vasoconstriction; Vasodilation; Vasodilator Agents | 1983 |
Adrenergic receptors and increased reactivity of aortic smooth muscle in renal hypertensive rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Caffeine; Calcium; Dose-Response Relationship, Drug; Hypertension, Renal; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sodium | 1982 |
[Nature of the dual caffeine-sodium benzoate effect on the tonic component of the potassium contracture of the myocardium in the frog].
Topics: Animals; Benzoates; Benzoic Acid; Caffeine; Calcium; Gallopamil; In Vitro Techniques; Ion Channels; Muscle Tonus; Myocardial Contraction; Nifedipine; Potassium; Rana temporaria; Tetracaine | 1984 |
Indomethacin suppresses the early cardiodepressant factor released by endotoxin in the rat: possible involvement of a prostacyclin-related material.
Topics: Animals; Caffeine; Cells, Cultured; Depression, Chemical; Epoprostenol; Imidazoles; Indomethacin; Male; Myocardial Contraction; Myocardial Depressant Factor; Nifedipine; Peptide Biosynthesis; Rats; Shock, Septic | 1983 |
Nisoldipine-induced relaxation in intact and skinned smooth muscles of rabbit coronary arteries.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Contractile Proteins; Coronary Vessels; Drug Interactions; Electrophysiology; Female; In Vitro Techniques; Male; Membrane Potentials; Muscle Relaxation; Nifedipine; Nisoldipine; Potassium; Rabbits; Tetrodotoxin; Vasodilator Agents | 1984 |
Influence of rat serum on cultured newborn rat heart cell inotropism.
Topics: Animals; Animals, Newborn; Blood; Caffeine; Calcium; Cells, Cultured; Diltiazem; Myocardial Contraction; Myocardium; Nifedipine; Rats | 1984 |
Successful treatment of ergotism with nifedipine.
Topics: Angiography; Aortography; Caffeine; Drug Combinations; Ergotamine; Ergotism; Female; Humans; Ischemia; Leg; Middle Aged; Nifedipine; Spasm | 1984 |
Effect of dantrolene sodium on the contractility of rabbit jejunum in vitro.
Topics: Animals; Caffeine; Calcium; Dantrolene; Female; In Vitro Techniques; Jejunum; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Rabbits | 1981 |
Leukotriene C4-stimulated contractions in bullfrog lung are affected by cold acclimation and calcium antagonists.
Topics: Acclimatization; Animals; Caffeine; Calcium Channel Blockers; Calcium-Transporting ATPases; Cold Temperature; Contracture; Egtazic Acid; Eicosapentaenoic Acid; Female; Hot Temperature; Leukotriene C4; Lung; Male; Nicardipine; Nifedipine; Nitrendipine; Rana catesbeiana; SRS-A; Terpenes; Thapsigargin; Verapamil | 1995 |
Nifedipine and nicardipine potentiate glucagon-stimulated glycogenolysis in primary cultures of rat hepatocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Caffeine; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Glucagon; Glycogen; Liver; Male; Nicardipine; Nifedipine; Papaverine; Rats; Rats, Wistar | 1993 |
Effects of nifedipine and Bay K 8644 on contractile activities in single skeletal muscle fibers of the frog.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adenine; Animals; Caffeine; Calcium; Cell Membrane; Dihydropyridines; Electric Stimulation; Electrophysiology; In Vitro Techniques; Microelectrodes; Muscle Contraction; Muscles; Nifedipine; Potassium; Xenopus laevis | 1994 |
Voltage control of calcium transients elicited by caffeine and tetracaine in cultured rat muscle cells.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Cells, Cultured; Membrane Potentials; Microscopy, Fluorescence; Models, Biological; Muscle, Skeletal; Nifedipine; Patch-Clamp Techniques; Perfusion; Rats; Sarcolemma; Tetracaine | 1995 |
Grapefruit juice interactions with drugs.
Topics: Beverages; Caffeine; Citrus; Cyclosporine; Estrogens; Felodipine; Food-Drug Interactions; Humans; Midazolam; Nifedipine; Terfenadine | 1995 |
Pharmacological natures of caffeine-induced endothelium-dependent and -independent contraction in canine mesenteric artery.
Topics: Adenylyl Cyclases; Animals; Benzopyrans; Caffeine; Calcium; Calcium Channel Blockers; Colforsin; Cromakalim; Dogs; Edetic Acid; Egtazic Acid; Endothelium, Vascular; Female; In Vitro Techniques; Magnesium; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Potassium Channels; Pyrroles; Vasodilator Agents | 1995 |
The effect of calcium channel antagonists and BAY K 8644 on calcium fluxes of malignant hyperpyrexia-susceptible muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Diltiazem; Halothane; Malignant Hyperthermia; Muscle Contraction; Muscles; Nifedipine; Potassium Chloride; Sarcoplasmic Reticulum; Swine; Verapamil | 1993 |
Activation of a slow outward current by the calcium released during contraction of cultured rat skeletal muscle cells.
Topics: 4-Aminopyridine; Animals; Apamin; Caffeine; Calcium; Cells, Cultured; Cesium; Charybdotoxin; Egtazic Acid; Electric Conductivity; Electric Stimulation; Membrane Potentials; Muscle Contraction; Muscles; Nifedipine; Potassium; Rats; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1993 |
Ca(2+)-channel blockade in rat thoracic aorta by crychine isolated from Cryptocarya chinensis Hemsl.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Bridged Bicyclo Compounds; Caffeine; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; Dioxoles; Drug Interactions; Female; Male; Muscle Contraction; Nifedipine; Norepinephrine; Plant Extracts; Plants, Medicinal; Potassium; Rats; Rats, Wistar | 1993 |
Ca2+ mobilization by caffeine in single smooth muscle cells of the rat tail artery.
Topics: Animals; Arteries; Caffeine; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cell Size; Dose-Response Relationship, Drug; Fura-2; Gallic Acid; Male; Muscle, Smooth, Vascular; Nifedipine; Patch-Clamp Techniques; Rats; Rats, Wistar; Reproducibility of Results; Ryanodine; Spectrometry, Fluorescence; Tail; Terpenes; Thapsigargin | 1994 |
Rise in cytoplasmic Ca2+ induced by monensin in bovine medullary chromaffin cells.
Topics: Adrenal Medulla; Animals; Caffeine; Calcium; Calcium Channels; Cattle; Cells, Cultured; Cytoplasm; Monensin; Nifedipine; Sodium; Sodium Channels; Tetrodotoxin | 1994 |
Contribution of extracellular calcium to intracellular pH-induced changes in spontaneous force of rat portal vein.
Topics: Ammonium Chloride; Animals; Caffeine; Calcium; Extracellular Space; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Fluid; Ion Transport; Magnesium; Male; Nifedipine; Portal Vein; Rats; Rats, Wistar; Vasoconstriction | 1995 |
Ryanodine-sensitive intracellular Ca2+ stores in isolated rabbit penile erectile tissue.
Topics: Animals; Caffeine; Calcium; Electric Stimulation; In Vitro Techniques; Intracellular Membranes; Male; Nifedipine; Penile Erection; Penis; Phenylephrine; Potassium; Rabbits; Ryanodine; Solutions | 1995 |
1,25-Dihydroxyvitamin D3 evokes oscillations of intracellular calcium in a pancreatic beta-cell line.
Topics: Animals; Caffeine; Calcitriol; Calcium; Calcium Channels; Cell Line; Islets of Langerhans; Lanthanum; Manganese; Nifedipine; Periodicity; Rats; Ryanodine; Terpenes; Thapsigargin | 1995 |
Mode of action of an inhibitory neuropeptide SchistoFLRFamide on the locust oviduct visceral muscle.
Topics: Amino Acid Sequence; Animals; Caffeine; Calcimycin; Calcium; Calcium Channels; Cobalt; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Female; Grasshoppers; Ion Channel Gating; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neuropeptides; Nifedipine; Oviducts; Tetradecanoylphorbol Acetate | 1995 |
Evidence that depletion of internal calcium stores sensitive to noradrenaline elicits a contractile response dependent on extracellular calcium in rat aorta.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Caffeine; Calcium; Extracellular Space; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Papaverine; Rats; Rats, Wistar; Serotonin | 1993 |
Calcium concentration changes in the calyciform nerve terminal of the avian ciliary ganglion after tetanic stimulation.
Topics: Adenosine; Animals; Caffeine; Calcium; Chick Embryo; Electric Stimulation; Ganglia, Parasympathetic; Long-Term Potentiation; Nerve Endings; Nifedipine; Potassium; Terpenes; Tetany; Thapsigargin | 1994 |
Halothane and enflurane constrict canine mesenteric arteries by releasing Ca2+ from intracellular Ca2+ stores.
Topics: Animals; Arginine; Caffeine; Calcium; Dogs; Enflurane; Fluorescent Dyes; Fura-2; Halothane; In Vitro Techniques; Indomethacin; Isometric Contraction; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Nitroarginine; Ryanodine; Spectrometry, Fluorescence; Vasoconstriction | 1994 |
Evidence for multiple open states of the Ca2+ channels in smooth muscle cells isolated from the guinea-pig detrusor.
Topics: Animals; Caffeine; Calcium Channels; Chloride Channels; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Ion Transport; Kinetics; Male; Membrane Potentials; Models, Biological; Muscle, Smooth; Nifedipine; Tetrodotoxin; Urinary Bladder | 1993 |
Ionic currents and endothelin signaling in smooth muscle cells from rat renal resistance arteries.
Topics: 4-Aminopyridine; Animals; Arterioles; Caffeine; Calcium; Cell Membrane; Cobalt; Egtazic Acid; Electric Conductivity; Endothelins; Fluorescent Dyes; Fura-2; In Vitro Techniques; Kidney; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nifedipine; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Renal Circulation; Signal Transduction; Spectrometry, Fluorescence; Tetraethylammonium; Tetraethylammonium Compounds; Vascular Resistance | 1994 |
Effect of extracellular ions and modulators of calcium transport on survival of tert-butyl hydroperoxide exposed cardiac myocytes.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Cell Size; Cell Survival; Deferoxamine; Diacetyl; Heart; Lipid Peroxidation; Male; Myocardium; Nifedipine; Oxidants; Peroxides; Propyl Gallate; Rats; Rats, Sprague-Dawley; Sodium; tert-Butylhydroperoxide; Verapamil | 1993 |
Acute hypoxia increases cytosolic calcium in cultured pulmonary arterial myocytes.
Topics: Acute Disease; Animals; Caffeine; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cells, Cultured; Cytosol; Fura-2; Hypoxia; Male; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Nifedipine; Oxygen; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Terpenes; Thapsigargin; Verapamil | 1993 |
The actions of caffeine and 2,3-butanedione monoxime on calcium transients in human vascular smooth muscle.
Topics: Caffeine; Calcium; Calcium Channels; Diacetyl; Female; Histamine; Humans; In Vitro Techniques; Membrane Potentials; Muscle, Smooth, Vascular; Nifedipine; Phosphorylation; Potassium; Sodium | 1993 |
Involvement of the dihydropyridine receptor and internal Ca2+ stores in myoblast fusion.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium-Transporting ATPases; Cell Fusion; Cell Line; Creatine Kinase; Enzyme Inhibitors; Indolizines; Ion Channel Gating; Muscle Fibers, Skeletal; Muscle Proteins; Muscles; Nifedipine; Phenethylamines; Rats; Ryanodine; Ryanodine Receptor Calcium Release Channel; Terpenes; Thapsigargin | 1996 |
Differential vasorelaxant effects of levcromakalim and P1060 in the isolated KCl- and RbCl-precontracted human saphenous vein: possible involvement of intracellular Ca2+ stores.
Topics: Benzopyrans; Caffeine; Calcium; Chlorides; Cromakalim; Guanidines; Humans; In Vitro Techniques; Nifedipine; Norepinephrine; Potassium Channels; Potassium Chloride; Pyrroles; Rubidium; Saphenous Vein; Vasodilator Agents | 1995 |
Tirapazamine (SR 4233) interrupts cell cycle progression and induces apoptosis.
Topics: Animals; Apoptosis; Caffeine; Cell Cycle; Cell Division; Cell Line; Cricetinae; Cricetulus; DNA Damage; Electrophoresis, Agar Gel; Fibroblasts; Flow Cytometry; Mitotic Index; Nifedipine; Ploidies; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 1996 |
Endothelin-induced contractions in human placental blood vessels are enhanced in intrauterine growth retardation, and modulated by agents that regulate levels of intracellular calcium.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adult; Arteries; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium-Transporting ATPases; Endothelins; Enzyme Inhibitors; Female; Fetal Growth Retardation; Humans; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Phosphodiesterase Inhibitors; Placental Circulation; Pregnancy; Ryanodine; Terpenes; Thapsigargin | 1995 |
Angiotensin II regulation of intracellular calcium in astroglia cultured from rat hypothalamus and brainstem.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Astrocytes; Biphenyl Compounds; Brain Stem; Cadmium; Caffeine; Calcium; Calcium Channel Blockers; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gadolinium; Hypothalamus; Imidazoles; Indoles; Losartan; Nifedipine; Phosphodiesterase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Ryanodine; Terpenes; Tetrazoles; Thapsigargin; Time Factors | 1996 |
Possible mechanism of the potent vasoconstrictor actions of ryanodine on femoral arteries from spontaneously hypertensive rats.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Femoral Artery; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Phosphodiesterase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ryanodine; Sarcoplasmic Reticulum; Verapamil | 1996 |
Interleukin-1 beta stimulation of 45Ca2+ release from rat striatal slices.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Chelating Agents; Egtazic Acid; In Vitro Techniques; Interleukin-1; Male; Neostriatum; Nifedipine; Pertussis Toxin; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Stimulation, Chemical; Virulence Factors, Bordetella | 1996 |
Major difference between rat and guinea-pig ureter in the ability of agonists and caffeine to release Ca2+ and influence force.
Topics: Animals; Caffeine; Calcium; Carbachol; Guinea Pigs; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Nifedipine; Oxytocin; Rats; Ureter | 1995 |
Altered bioelectrical and mechanical activities of rat gastric smooth muscle preparations by inhibiting enterocytogenin.
Topics: Amiloride; Animals; Apamin; Caffeine; Calcium; Calcium Channel Blockers; Diuretics; Electrophysiology; Gastric Mucosa; Intestines; Membranes; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Peptides; Rats; Stomach | 1996 |
Characterization of an oxytocin-induced rise in [Ca2+]i in single human myometrium smooth muscle cells.
Topics: Biological Transport; Caffeine; Calcium; Calcium-Transporting ATPases; Enzyme Inhibitors; Female; Humans; Muscle, Smooth; Myometrium; Nifedipine; Oxytocin; Ryanodine; Thapsigargin | 1996 |
Hypoxic contraction of isolated rat pulmonary artery.
Topics: Animals; Caffeine; Cell Hypoxia; Cyclooxygenase Inhibitors; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Nifedipine; Nitric Oxide; Oxygen; Pulmonary Artery; Rats; Vasoconstriction; Vasodilator Agents | 1995 |
Effects of nifedipine and Bay K 8644 on the R-PIA and caffeine-induced changes in the locomotor activity of rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Dose-Response Relationship, Drug; Locomotion; Male; Nifedipine; Rats; Rats, Wistar | 1996 |
Possible mechanism of the potent vasoconstrictor responses to ryanodine in dog cerebral arteries.
Topics: Animals; Benzopyrans; Caffeine; Calcium; Calcium Channel Blockers; Cerebral Arteries; Cromakalim; Dogs; Female; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Nifedipine; Phosphodiesterase Inhibitors; Potassium; Pyrroles; Ryanodine; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
Reduced Ca2+ current, charge movement, and absence of Ca2+ transients in skeletal muscle deficient in dihydropyridine receptor beta 1 subunit.
Topics: Animals; Barium; Caffeine; Calcium; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Electric Stimulation; Mice; Mice, Knockout; Muscle Contraction; Muscle, Skeletal; Nifedipine; Patch-Clamp Techniques | 1996 |
Reloading of Ca(2+)-depleted sarcoplasmic reticulum during rest in guinea pig ventricular myocytes.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Cold Temperature; Guinea Pigs; Heart Ventricles; Indoles; Myocardial Contraction; Myocardium; Nickel; Nifedipine; Osmolar Concentration; Rest; Sarcoplasmic Reticulum; Temperature; Time Factors | 1996 |
Effects of midazolam on contractions in smooth muscle of the rabbit mesenteric artery.
Topics: Adrenergic alpha-Agonists; Anesthetics, Intravenous; Animals; Caffeine; Calcium Channel Blockers; Dose-Response Relationship, Drug; Hypnotics and Sedatives; In Vitro Techniques; Male; Mesenteric Arteries; Midazolam; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium; Rabbits | 1997 |
Alpha-adrenoceptor activation of a chloride conductance in rat iris arterioles.
Topics: Animals; Arterioles; Caffeine; Calcium Channel Blockers; Chlorides; Electric Conductivity; Electric Stimulation; Electrophysiology; Female; Intracellular Membranes; Ions; Iris; Male; Nervous System Physiological Phenomena; Nifedipine; Rats; Receptors, Adrenergic, alpha; Temperature; Vasoconstriction | 1996 |
BAY K 8644 and ClO4- potentiate caffeine contracture without Ca2+ release channel activation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Drug Synergism; In Vitro Techniques; Muscle Contraction; Muscle, Skeletal; Nifedipine; Perchlorates; Potassium; Rana catesbeiana; Sodium Compounds | 1997 |
Contraction and relaxation in the absence of a sarcoplasmic reticulum: muscle fibres in the small pelagic tunicate Doliolum.
Topics: Animals; Caffeine; Calcium; Cobalt; Muscle Contraction; Muscle Relaxation; Nifedipine; Ryanodine; Sarcoplasmic Reticulum; Sodium; Urochordata | 1997 |
Development of mechanisms regulating intracellular Ca2+ concentration in cardiac muscle cells of early chick embryos.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Chick Embryo; Cytophotometry; Fluorescent Dyes; Fura-2; Heart; Homeostasis; Magnesium; Mesoderm; Microscopy, Electron; Muscle Proteins; Myocardium; Nifedipine; Ryanodine; Ryanodine Receptor Calcium Release Channel | 1997 |
Oscillatory Cl- current induced by angiotensin II in rat pulmonary arterial myocytes: Ca2+ dependence and physiological implication.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cell Membrane; Chlorides; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Fluorescent Dyes; Indoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Niflumic Acid; Patch-Clamp Techniques; Periodicity; Phosphodiesterase Inhibitors; Pulmonary Artery; Rats; Rats, Wistar; Thapsigargin | 1997 |
The effects of cyclopiazonic acid on intracellular Ca2+ in aortic smooth muscle cells from DOCA-hypertensive rats.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Central Nervous System Stimulants; Desoxycorticosterone; Enzyme Inhibitors; Hypertension; Indoles; Intracellular Fluid; Ion Transport; Male; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1997 |
Calcium release from intracellular stores and excitation-contraction coupling in intestinal smooth muscle.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Carbachol; Cell Compartmentation; Cells, Cultured; Dantrolene; Female; Gastrointestinal Motility; Homeostasis; Intestine, Small; Jejunum; Male; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Nifedipine; Ryanodine | 1997 |
Endothelin receptor-mediated Ca2+ mobilization and contraction in bovine oviductal arteries: comparison with noradrenaline and potassium.
Topics: Animals; Cadmium; Caffeine; Calcium; Calcium Channel Agonists; Cattle; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-2; Endothelin-3; Endothelium, Vascular; Fallopian Tubes; Female; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; Nickel; Nifedipine; Nitroarginine; Norepinephrine; Peptides, Cyclic; Potassium; Receptors, Endothelin; Ryanodine; Viper Venoms | 1997 |
Dependence of myocardial hypothermia tolerance on sources of activator calcium.
Topics: Adaptation, Physiological; Animals; Caffeine; Calcium; Calcium Channel Blockers; Female; Hibernation; Hypothermia; Hypothermia, Induced; Male; Myocardial Contraction; Myocardium; Nifedipine; Rats; Sciuridae; Species Specificity | 1997 |
Regulation of intracellular calcium in human esophageal smooth muscles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adult; Aged; Caffeine; Calcium; Calcium-Transporting ATPases; Carbachol; Cells, Cultured; Egtazic Acid; Enzyme Inhibitors; Esophageal Neoplasms; Esophagus; Female; Homeostasis; Humans; Indoles; Kinetics; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Sarcoplasmic Reticulum | 1997 |
Ca2+ current and Ca(2+)-activated chloride current in isolated smooth muscle cells of the sheep urethra.
Topics: Action Potentials; Animals; Anthracenes; Barium; Caffeine; Calcium; Calcium Channel Blockers; Chloride Channels; Chlorides; Female; In Vitro Techniques; Male; Muscle, Smooth; Nifedipine; Niflumic Acid; Patch-Clamp Techniques; Sheep; Urethra | 1997 |
Sarcoplasmic reticulum Ca2+ content, L-type Ca2+ current and the Ca2+ transient in rat myocytes during beta-adrenergic stimulation.
Topics: Adrenergic beta-Agonists; Animals; Caffeine; Calcium; Calcium Channels; Calcium Channels, L-Type; Calcium-Transporting ATPases; Cells, Cultured; Heart; Isoproterenol; Kinetics; Male; Membrane Potentials; Myocardium; Nifedipine; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Sarcoplasmic Reticulum; Thapsigargin | 1997 |
L-type Ca2+ current in fish cardiac myocytes: effects of thermal acclimation and beta-adrenergic stimulation.
Topics: Acclimatization; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Barium; Caffeine; Calcium; Carps; Colforsin; Heart; In Vitro Techniques; Ion Channel Gating; Isoproterenol; Membrane Potentials; Microscopy, Electron; Nifedipine; Oncorhynchus mykiss; Sarcolemma; Species Specificity; Temperature | 1998 |
Endothelin-1 and insulin activate the steady-state voltage dependent R-type Ca2+ channel in aortic smooth muscle cells via a pertussis toxin and cholera toxin sensitive G-protein.
Topics: Animals; Aorta; Caffeine; Calcium Channels; Cholera Toxin; Endothelin-1; GTP-Binding Proteins; Indoles; Insulin; Ion Transport; Isradipine; Maleimides; Muscle, Smooth, Vascular; Nifedipine; Pertussis Toxin; Protein Kinase C; Rabbits; Ryanodine; Virulence Factors, Bordetella | 1998 |
Role of intracellular Ca2+ stores in smooth muscle of human penile erectile tissue.
Topics: Animals; Caffeine; Calcium; Electric Stimulation; Erectile Dysfunction; Humans; In Vitro Techniques; Intracellular Fluid; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Penis; Phenylephrine; Rabbits; Ryanodine | 1998 |
Ca2+-dependence of vasoconstriction mediated by alpha1A-adrenoceptors in perfused rat hindlimb: a pharmacological approach.
Topics: Animals; Caffeine; Calcium; Calcium Channels; Hindlimb; Male; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Perfusion; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
Electromechanical coupling in human vas deferens: effects of agents that modulate intracellular release of calcium.
Topics: Caffeine; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Male; Muscle Contraction; Nifedipine; Ryanodine; Vas Deferens | 1998 |
Ryanodine- and cyclopiazonic acid-sensitive components in human vas deferens contractions to noradrenaline.
Topics: Adrenergic alpha-Agonists; Caffeine; Calcium Channel Blockers; Calcium-Transporting ATPases; Enzyme Inhibitors; Humans; Indoles; Male; Muscle Contraction; Nifedipine; Norepinephrine; Ryanodine; Vas Deferens | 1998 |
Calcium in sympathetic boutons of rat superior cervical ganglion during facilitation, augmentation and potentiation.
Topics: Action Potentials; Adenosine; Adrenergic Fibers; Agatoxins; Animals; Caffeine; Calcium; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Central Nervous System Stimulants; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Ionophores; Kinetics; Nifedipine; omega-Conotoxin GVIA; Peptides; Presynaptic Terminals; Rats; Rats, Wistar; Ryanodine; Spider Venoms; Superior Cervical Ganglion; Synaptic Transmission; Thapsigargin | 1998 |
The role of a ryanodine-sensitive Ca(2+)-store in the regulation of smooth muscle tone of the cat gastric fundus.
Topics: Animals; Caffeine; Calcium; Calcium-Transporting ATPases; Cats; Enzyme Inhibitors; Gastric Fundus; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Nifedipine; Ruthenium Red; Ryanodine; Stomach | 1998 |
Spontaneous and neurally activated depolarizations in smooth muscle cells of the guinea-pig urethra.
Topics: Adenosine Triphosphate; Animals; Caffeine; Egtazic Acid; Electric Stimulation; Evoked Potentials; Female; Guanethidine; Guinea Pigs; In Vitro Techniques; Indoles; Membrane Potentials; Microelectrodes; Muscle, Smooth; Neuromuscular Junction; Nifedipine; Niflumic Acid; Phenylephrine; Stochastic Processes; Synaptic Transmission; Tetrodotoxin; Urethra | 1999 |
Identification of rhythmically active cells in guinea-pig stomach.
Topics: Animals; Caffeine; Female; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Nifedipine; Pyloric Antrum; Stomach; Time Factors | 1999 |
Ca2+ buffering action of sarcoplasmic reticulum on Bay k 8644-induced Ca2+ influx in rat femoral arterial smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Enzyme Inhibitors; Femoral Artery; In Vitro Techniques; Indoles; Mice; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Potassium; Rats; Rats, Inbred WKY; Ryanodine; Sarcoplasmic Reticulum; Thapsigargin | 1999 |
Sympathetic neuroeffector transmission in the rat anococcygeus muscle.
Topics: Action Potentials; Animals; Caffeine; Calcium Channel Blockers; Chlorides; Electric Stimulation; Guanethidine; In Vitro Techniques; Male; Membrane Potentials; Muscle, Skeletal; Neuroeffector Junction; Nifedipine; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rats; Sympathetic Nervous System; Sympatholytics; Synaptic Transmission | 1999 |
Calcium waves in colonic myocytes produced by mechanical and receptor-mediated stimulation.
Topics: Animals; Biomechanical Phenomena; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Colon; Kinetics; Lanthanum; Muscle, Smooth; Nifedipine; Physical Stimulation; Rabbits; Ryanodine; Substance P; Thapsigargin | 1999 |
Store-operated Ca2+ influx and voltage-gated Ca2+ channels coupled to exocytosis in pheochromocytoma (PC12) cells.
Topics: Animals; Biological Transport; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, N-Type; Catecholamines; Central Nervous System Stimulants; Electrophysiology; Exocytosis; Neurons; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; PC12 Cells; Peptides; Potassium; Rats; Spider Venoms | 1999 |
Contribution of sarcoplasmic reticulum calcium uptake and L-type calcium channels to altered vascular responsiveness in the aorta of renal hypertensive rats.
Topics: Animals; Aorta; Caffeine; Calcium; Calcium Channels, L-Type; Hypertension, Renal; In Vitro Techniques; Male; Nifedipine; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Thapsigargin; Vasoconstriction | 1999 |
Nitrergic relaxation of the mouse gastric fundus is mediated by cyclic GMP-dependent and ryanodine-sensitive mechanisms.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; Caffeine; Calcium Channel Blockers; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Muscle Relaxation; Muscle, Smooth; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Oxadiazoles; Quinoxalines; Ryanodine | 2000 |
Investigation of the role of intracellular Ca(2+) stores in generation of the muscarinic agonist-induced slow afterdepolarization (sADP) in guinea-pig olfactory cortical neurones in vitro.
Topics: Action Potentials; Animals; Caffeine; Calcium; Calcium Channel Blockers; Dantrolene; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Guinea Pigs; In Vitro Techniques; Indoles; Male; Membrane Potentials; Muscarinic Agonists; Neurons; Nifedipine; Olfactory Pathways; Oxotremorine; Receptors, Metabotropic Glutamate; Receptors, Muscarinic; Ryanodine; Ryanodine Receptor Calcium Release Channel; Synaptic Transmission; Thapsigargin | 2000 |
Role of calcium stores and membrane voltage in the generation of slow wave action potentials in guinea-pig gastric pylorus.
Topics: Action Potentials; Animals; Cadmium; Caffeine; Calcium; Calcium Channel Blockers; Cell Membrane; Chelating Agents; Egtazic Acid; Guinea Pigs; Heparin; In Vitro Techniques; Indoles; Membrane Potentials; Muscle, Smooth; Nifedipine; Pyloric Antrum; Ryanodine; Stomach; Tetrodotoxin | 2000 |
Mechanisms of excitatory neuromuscular transmission in the guinea-pig urinary bladder.
Topics: Action Potentials; Animals; Caffeine; Calcium; Calcium Channel Blockers; Electric Stimulation; Female; Fluorescent Dyes; Fura-2; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Male; Membrane Potentials; Microelectrodes; Neuromuscular Junction; Nifedipine; Phosphodiesterase Inhibitors; Receptors, Purinergic; Ryanodine; Synaptic Transmission; Urinary Bladder | 2000 |
Voltage-independent calcium entry in hypoxic pulmonary vasoconstriction of intrapulmonary arteries of the rat.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Chelating Agents; Diltiazem; Dinucleoside Phosphates; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Hypoxia; Imidazoles; In Vitro Techniques; Ion Channel Gating; Lanthanum; Male; Membrane Potentials; Nifedipine; Phosphodiesterase Inhibitors; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Wistar; Ryanodine; Thapsigargin; Vasoconstriction; Verapamil | 2000 |
The involvement of intracellular Ca(2+) in 5-HT(1B/1D) receptor-mediated contraction of the rabbit isolated renal artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Actin Cytoskeleton; Animals; Caffeine; Calcium; Calcium Channel Blockers; Capillary Permeability; Dose-Response Relationship, Drug; Female; Fluorescence; Fura-2; Imidazoles; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Potassium; Rabbits; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Renal Artery; Serotonin; Thapsigargin; Vasoconstrictor Agents | 2000 |
Cyclic AMP-mediated inhibition of noradrenaline-induced contraction and Ca2+ influx in guinea-pig vas deferens.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Caffeine; Calcium; Calcium Channel Blockers; Colforsin; Cyclic AMP; Guinea Pigs; Intracellular Membranes; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Osmolar Concentration; Potassium; Vas Deferens | 2000 |
Na(+)/Ca(2+)-exchange activity regulates contraction and SR Ca(2+) content in rainbow trout atrial myocytes.
Topics: Animals; Atrial Function; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Electric Conductivity; Linear Models; Membrane Potentials; Myocardial Contraction; Nickel; Nifedipine; Oncorhynchus mykiss; Patch-Clamp Techniques; Sarcoplasmic Reticulum; Sodium; Sodium-Calcium Exchanger | 2000 |
Chronic depolarization induced by veratridine increases the survival of rat retinal ganglion cells 'in vitro'.
Topics: Amiloride; Animals; Caffeine; Calcium Channel Blockers; Calcium Channels, T-Type; Cell Death; Cell Survival; Cells, Cultured; Chelating Agents; Dantrolene; Diuretics; Dizocilpine Maleate; Egtazic Acid; Excitatory Amino Acid Antagonists; In Vitro Techniques; Membrane Potentials; Muscle Relaxants, Central; Nifedipine; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Veratridine | 2000 |
Mitochondria mediate tumor necrosis factor-alpha/NF-kappaB signaling in skeletal muscle myotubes.
Topics: Amobarbital; Animals; Antimycin A; Caffeine; Ceramides; Endocannabinoids; Enzyme Inhibitors; Ethanolamines; Melitten; Mitochondria, Muscle; Muscle Development; Muscle, Skeletal; NF-kappa B; Nifedipine; Oleic Acids; Phospholipases A; Phospholipases A2; Protein Kinase C; Rats; Reactive Oxygen Species; Recombinant Proteins; Rotenone; Ruthenium Red; Signal Transduction; Tumor Necrosis Factor-alpha | 1999 |
Signalling mechanisms underlying the myogenic response in human subcutaneous resistance arteries.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aged; Analysis of Variance; Arteries; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Cyclohexanones; Enzyme Inhibitors; Estrenes; Female; Humans; In Vitro Techniques; Indoles; Lipoprotein Lipase; Male; Middle Aged; Muscle, Smooth, Vascular; Naphthalenes; Nifedipine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrrolidinones; Ryanodine; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Type C Phospholipases; Vascular Resistance | 2001 |
Role of IP(3) in modulation of spontaneous activity in pacemaker cells of rabbit urethra.
Topics: Animals; Boron Compounds; Caffeine; Calcium; Cell Membrane; Female; In Vitro Techniques; Indoles; Inositol 1,4,5-Trisphosphate; Male; Membrane Potentials; Muscle, Smooth; Nifedipine; Rabbits; Ryanodine; Urethra; Urinary Bladder | 2001 |
[Spontaneous transient outward currents in smooth muscle cells of the rat tail artery].
Topics: Animals; Arteries; Caffeine; Calcium Channel Blockers; Calcium Channels, L-Type; Electric Conductivity; In Vitro Techniques; Membrane Potentials; Muscle, Smooth, Vascular; Nifedipine; Patch-Clamp Techniques; Rats; Rats, Wistar; Tail; Tetraethylammonium Compounds | 2001 |
Nifedipine blocks Ca2+ store refilling through a pathway not involving L-type Ca2+ channels in rabbit arteriolar smooth muscle.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Choroid; Endothelin-1; Membrane Potentials; Microcirculation; Muscle, Smooth, Vascular; Nifedipine; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rabbits | 2001 |
Calcium waves induced by hypertonic solutions in intact frog skeletal muscle fibres.
Topics: Anesthetics, Local; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cell Membrane; Electrophysiology; Hypertonic Solutions; Ion Channel Gating; Membrane Potentials; Microscopy, Electron; Muscle Fibers, Skeletal; Muscle, Skeletal; Nifedipine; Phosphodiesterase Inhibitors; Potassium Chloride; Rana temporaria; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sucrose; Tetracaine | 2001 |
Diabetes-induced changes in calcium homeostasis and the effects of calcium channel blockers in rat and mice nociceptive neurons.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Ganglia, Spinal; Homeostasis; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Nifedipine; Nociceptors; Rats; Rats, Wistar; Signal Transduction; Substantia Gelatinosa | 2001 |
Ca(2+) sparks and BK currents in gallbladder myocytes: role in CCK-induced response.
Topics: Aniline Compounds; Animals; Boron Compounds; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cholecystokinin; Enzyme Inhibitors; Fluorescent Dyes; Gallbladder; Guinea Pigs; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Muscle, Smooth; Nifedipine; Patch-Clamp Techniques; Peptides; Phosphodiesterase Inhibitors; Potassium; Potassium Channels; Potassium Channels, Calcium-Activated; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Thapsigargin; Xanthenes | 2002 |
Mechanisms of Ca2+ overload induced by extracellular H2O2 in quiescent isolated rat cardiomyocytes.
Topics: Alkaloids; Animals; Benzophenanthridines; Caffeine; Calcium; Calcium Channel Blockers; Catalase; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; Free Radicals; Hydrogen Peroxide; In Vitro Techniques; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Nifedipine; Oxidants; Phenanthridines; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Sarcolemma; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger | 2001 |
Deleterious effects of nifedipine on smooth muscle cells implies alterations of intracellular calcium signaling.
Topics: Amlodipine; Aorta; Caffeine; Calcium; Calcium Channel Blockers; Calcium Signaling; Calcium-Transporting ATPases; Cells, Cultured; Endoplasmic Reticulum; Enzyme Inhibitors; Felodipine; Genistein; Humans; Muscle, Smooth, Vascular; Nifedipine; Protein-Tyrosine Kinases; Thapsigargin | 2001 |
Calcium-induced transitions between the spontaneous miniature outward and the transient outward currents in retinal amacrine cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amacrine Cells; Ambystoma; Animals; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Electric Stimulation; Electrophysiology; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Nifedipine; Peptides; Phosphodiesterase Inhibitors; Potassium Channels, Calcium-Activated; Reaction Time; Retinal Ganglion Cells; Ryanodine Receptor Calcium Release Channel | 2002 |
What are the signaling pathways used by norepinephrine to contract the artery? A demonstration using guinea pig aortic ring segments.
Topics: Animals; Aorta; Caffeine; Calcium; Calcium Channel Blockers; Cardiovascular Physiological Phenomena; Central Nervous System Stimulants; Endothelium, Vascular; Extracellular Space; Guinea Pigs; In Vitro Techniques; Laboratories; Nifedipine; Norepinephrine; Phorbol 12,13-Dibutyrate; Physiology; Potassium; Signal Transduction; Teaching; Vasoconstriction; Vasoconstrictor Agents | 2002 |
Contribution of nifedipine-insensitive voltage-dependent Ca2+ channel to diameter regulation in rabbit mesenteric artery.
Topics: Algorithms; Animals; Arterioles; Cadmium; Caffeine; Calcium; Calcium Channel Blockers; Electrophysiology; Fluorescent Dyes; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Microscopy, Video; Muscle, Smooth, Vascular; Nifedipine; Patch-Clamp Techniques; Rabbits; Tetrodotoxin | 2002 |
Buspirone-induced antinociception is mediated by L-type calcium channels and calcium/caffeine-sensitive pools in mice.
Topics: 5-Hydroxytryptophan; Analgesics; Animals; Buspirone; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Chloride; Central Nervous System Stimulants; Chelating Agents; Egtazic Acid; Female; Fluoxetine; Injections, Intraventricular; Mice; Nifedipine; Pain Measurement; Reaction Time; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Ryanodine; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists | 2003 |
Ca2+ phase waves: a basis for cellular pacemaking and long-range synchronicity in the guinea-pig gastric pylorus.
Topics: Acetylcholine; Algorithms; Animals; Biological Clocks; Caffeine; Calcium Channel Blockers; Calcium Signaling; Calcium-Transporting ATPases; Electrophysiology; Guinea Pigs; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Microelectrodes; Microscopy, Confocal; Models, Biological; Models, Neurological; Nifedipine; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Pylorus; Stomach | 2003 |
Phasic contractions of the rat portal vein depend on intracellular Ca2+ release stimulated by depolarization.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Chloride Channels; Cyclooxygenase Inhibitors; Electric Stimulation; Isotonic Solutions; Male; Nifedipine; Niflumic Acid; Phenylephrine; Phosphodiesterase Inhibitors; Portal Vein; Potassium; Protein Kinase C; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents | 2003 |
NTP, the photoproduct of nifedipine, activates caffeine-sensitive ion channels in leech neurons.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Membrane; Dihydropyridines; Dose-Response Relationship, Drug; Drug Synergism; Ganglia, Invertebrate; Intracellular Fluid; Ion Channels; Leeches; Membrane Potentials; Neurons; Nifedipine | 2003 |
Components of the intracellular cAMP system supporting the olfactory reception of amyl alcohol.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Aluminum Compounds; Animals; Antimetabolites; Caffeine; Calcium Channel Blockers; Calcium Chloride; Chelating Agents; Chlortetracycline; Colforsin; Cyclic AMP; Dideoxyadenosine; Egtazic Acid; Fluorides; In Vitro Techniques; Ionomycin; Ionophores; Microscopy, Fluorescence; Nifedipine; Olfactory Mucosa; Pentanols; Phosphodiesterase Inhibitors; Rana temporaria; Reaction Time; Signal Transduction; Smell | 2003 |
Store operated Ca2+ influx by selective depletion of ryanodine sensitive Ca2+ pools in primary human skeletal muscle cells.
Topics: Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Cyclohexanones; Diglycerides; Humans; Lipoprotein Lipase; Magnesium; Muscle Cells; Muscle, Skeletal; Nifedipine; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; Ryanodine; Ryanodine Receptor Calcium Release Channel; Time Factors; Type C Phospholipases | 2003 |
Governance of arteriolar oscillation by ryanodine receptors.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arterioles; Boron Compounds; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Enzyme Inhibitors; Hydronephrosis; Kidney Glomerulus; Male; Nifedipine; Ouabain; Periodicity; Phosphodiesterase Inhibitors; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Renal Circulation; Ryanodine; Ryanodine Receptor Calcium Release Channel; Tetraethylammonium; Thapsigargin; Vasoconstriction | 2003 |
An increase in intracellular calcium concentration that is induced by basolateral CO2 in rabbit renal proximal tubule.
Topics: Animals; Bicarbonates; Caffeine; Calcium; Calcium Channel Blockers; Carbon Dioxide; Enzyme Inhibitors; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Membranes; Kidney Tubules, Proximal; Nifedipine; Osmolar Concentration; Rabbits; Rotenone; Thapsigargin | 2003 |
Conformational coupling of DHPR and RyR1 in skeletal myotubes is influenced by long-range allosterism: evidence for a negative regulatory module.
Topics: Allosteric Regulation; Animals; Cadmium; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; DNA, Complementary; Lanthanum; Membrane Potentials; Mice; Molecular Conformation; Muscle Fibers, Skeletal; Muscle, Skeletal; Nifedipine; Recombinant Fusion Proteins; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Time Factors | 2004 |
Role of sarcoplasmic reticulum in control of membrane potential and nitrergic response in opossum lower esophageal sphincter.
Topics: Animals; Anthracenes; Atropine; Azepines; Caffeine; Calcium; Chloride Channels; Enzyme Inhibitors; Esophagogastric Junction; Female; Guanethidine; In Vitro Techniques; Indoles; Male; Membrane Potentials; Muscle, Smooth; Myosin-Light-Chain Kinase; Nifedipine; Niflumic Acid; Nitric Oxide; Opossums; Oxadiazoles; Quinoxalines; Ryanodine; Sarcoplasmic Reticulum; Substance P; Tetraethylammonium | 2003 |
Phosphatidylinositol 3-kinase modulates vascular smooth muscle contraction by calcium and myosin light chain phosphorylation-independent and -dependent pathways.
Topics: Animals; Caffeine; Calcium; Carotid Arteries; Chromones; Enzyme Inhibitors; Histamine; In Vitro Techniques; Kinetics; Morpholines; Muscle Contraction; Muscle, Smooth, Vascular; Myosin Light Chains; Myosin-Light-Chain Kinase; Nifedipine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Potassium Chloride; Signal Transduction; Swine | 2004 |
Effects of electrical shocks on Cai2+ and Vm in myocyte cultures.
Topics: Aniline Compounds; Animals; Caffeine; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Computer Simulation; Electric Stimulation; Electroporation; Fluorescent Dyes; Ion Channel Gating; Ion Transport; Membrane Potentials; Models, Cardiovascular; Muscle Cells; Myocytes, Cardiac; Nifedipine; Rats; Rats, Wistar; Sodium-Calcium Exchanger; Thapsigargin; Xanthenes | 2004 |
Requirement of ryanodine receptors for pacemaker Ca2+ activity in ICC and HEK293 cells.
Topics: Anesthetics, Local; Animals; Biological Clocks; Boron Compounds; Caffeine; Calcium; Calcium Channel Blockers; Cell Line; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Fluorescent Dyes; Fura-2; Humans; Ileum; Immunohistochemistry; Kinetics; Macrocyclic Compounds; Mice; Microscopy, Fluorescence; Muscle, Smooth; Nifedipine; Oxazoles; Proto-Oncogene Proteins c-kit; RNA, Messenger; Ryanodine; Ryanodine Receptor Calcium Release Channel; Tacrolimus; Tetracaine | 2004 |
L-type Ca2+ channel antagonists block voltage-dependent Ca2+ channels in identified leech neurons.
Topics: Animals; Caffeine; Calcium Channel Blockers; Calcium Channels, L-Type; Diltiazem; Gallopamil; Leeches; Membrane Potentials; Neurons; Nifedipine; Phosphodiesterase Inhibitors; Verapamil | 2004 |
The role of Ca2+ in the contractility of rabbit small intestine in vitro.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Duodenum; Ileum; In Vitro Techniques; Indoles; Jejunum; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium Chloride; Rabbits; Thapsigargin; Verapamil | 2004 |
Calcium mobilization is required for peroxynitrite-mediated enhancement of spontaneous transient outward currents in arteriolar smooth muscle cells.
Topics: Animals; Boron Compounds; Caffeine; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Electrophysiology; Female; Male; Membrane Potentials; Models, Biological; Molsidomine; Muscle, Smooth; Myocytes, Smooth Muscle; Nifedipine; Patch-Clamp Techniques; Peroxynitrous Acid; Potassium; Rats; Rats, Wistar; Ryanodine; Signal Transduction; Time Factors | 2004 |
Pacemaker potentials generated by interstitial cells of Cajal in the murine intestine.
Topics: Animals; Anti-Arrhythmia Agents; Biological Clocks; Caffeine; Calcium Channel Blockers; Central Nervous System Stimulants; Electrophysiology; Glyburide; In Vitro Techniques; Intestine, Small; Membrane Potentials; Mibefradil; Mice; Mice, Inbred BALB C; Myocytes, Smooth Muscle; Nifedipine; Pinacidil; Vasodilator Agents | 2005 |
Involvement of ryanodine receptors in pacemaker Ca2+ oscillation in murine gastric ICC.
Topics: Animals; Caffeine; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cells, Cultured; Gastric Mucosa; Inositol 1,4,5-Trisphosphate Receptors; Ion Channel Gating; Mice; Mice, Inbred BALB C; Myocytes, Smooth Muscle; Nifedipine; Receptors, Cytoplasmic and Nuclear; Ryanodine Receptor Calcium Release Channel; Stomach; Tacrolimus; Tissue Distribution | 2005 |
Sites and modes of action of proctolin and the FLP F2 on lobster cardiac muscle.
Topics: Animals; Cadmium; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Fluorescence; Membrane Potentials; Microelectrodes; Myocardial Contraction; Myocardium; Nephropidae; Neuropeptides; Nifedipine; Oligopeptides; Ryanodine; Sarcoplasmic Reticulum; Verapamil | 2005 |
Effects of calsequestrin over-expression on excitation-contraction coupling in isolated rabbit cardiomyocytes.
Topics: Adenoviridae; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calsequestrin; Central Nervous System Stimulants; Electrophysiology; Gene Expression; Genetic Vectors; Myocytes, Cardiac; Nifedipine; Patch-Clamp Techniques; Rabbits; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger; Transduction, Genetic | 2005 |
Caffeine-induced arrhythmias in murine hearts parallel changes in cellular Ca(2+) homeostasis.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Cytosol; Diltiazem; Electric Stimulation; Homeostasis; Immunosuppressive Agents; In Vitro Techniques; Mice; Mice, Inbred Strains; Myocytes, Cardiac; Nifedipine; Perfusion; Phosphodiesterase Inhibitors; Ryanodine Receptor Calcium Release Channel; Tachycardia, Ventricular; Tacrolimus | 2005 |
The frequency of calcium oscillations induced by 5-HT, ACH, and KCl determine the contraction of smooth muscle cells of intrapulmonary bronchioles.
Topics: Acetylcholine; Animals; Arterioles; Bronchi; Caffeine; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Central Nervous System Stimulants; Extracellular Space; Immunohistochemistry; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Potassium Chloride; Serotonin; Spectrometry, Fluorescence; Stimulation, Chemical | 2005 |
Sources of activator calcium ions in the contraction of smooth muscles in Aplysia kurodai.
Topics: Amiloride; Animals; Aplysia; Caffeine; Calcium; Cholinesterase Inhibitors; Histocytochemistry; Japan; Microscopy, Electron; Muscle Contraction; Muscle, Smooth; Nifedipine; Sarcolemma; Serotonin | 2005 |
Mechanism of ACh-induced asynchronous calcium waves and tonic contraction in porcine tracheal muscle bundle.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Central Nervous System Stimulants; Enzyme Inhibitors; Imidazoles; Indoles; Inositol 1,4,5-Trisphosphate; Muscle Contraction; Muscle, Smooth; Nifedipine; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium; Swine; Trachea | 2006 |
Nervous control of ciliary beating by Cl(-), Ca(2+) and calmodulin in Tritonia diomedea.
Topics: Caffeine; Calcium; Calcium Signaling; Calmodulin; Chlorides; Cilia; Neuropeptides; Nifedipine; Ryanodine Receptor Calcium Release Channel; Tritonia Sea Slug | 2006 |
Hemorheological efficiency of drugs, targeting on intracellular phosphodiesterase activity: in vitro study.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Blood Viscosity; Caffeine; Calcimycin; Calcium; Egtazic Acid; Erythrocyte Aggregation; Hemorheology; Humans; Male; Nifedipine; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Verapamil; Vinca Alkaloids | 2007 |
Calcium sparks activate calcium-dependent Cl- current in rat corpus cavernosum smooth muscle cells.
Topics: Animals; Boron Compounds; Caffeine; Calcium; Calcium Signaling; Cells, Cultured; Chloride Channels; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Male; Membrane Potentials; Myocytes, Smooth Muscle; Nifedipine; Patch-Clamp Techniques; Penis; Potassium; Rats; Rats, Sprague-Dawley; Ryanodine; Ryanodine Receptor Calcium Release Channel; Time Factors | 2007 |
Effects of (1R,9S)-beta-hydrastine on intracellular calcium concentration in PC12 cells.
Topics: Alkaloids; Animals; Benzylisoquinolines; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Dopamine; Enzyme Inhibitors; Nifedipine; PC12 Cells; Potassium; Rats; Thapsigargin | 2007 |
Cell culture alters Ca2+ entry pathways activated by store-depletion or hypoxia in canine pulmonary arterial smooth muscle cells.
Topics: Actins; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Calcium-Transporting ATPases; Cell Hypoxia; Cells, Cultured; Dogs; Enzyme Inhibitors; Imidazoles; Indoles; Inositol 1,4,5-Trisphosphate; Muscle Contraction; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nifedipine; Oxygen; Pulmonary Artery; Ryanodine Receptor Calcium Release Channel; Serotonin; Sodium-Calcium Exchanger; Thiourea | 2008 |
Conformational changes of a Ca2+-binding domain of the Na+/Ca2+ exchanger monitored by FRET in transgenic zebrafish heart.
Topics: Animals; Animals, Genetically Modified; Caffeine; Calcium Signaling; DNA, Antisense; Dogs; Embryo, Nonmammalian; Fluorescence Resonance Energy Transfer; Heart; Isoproterenol; Myocardial Contraction; Nifedipine; Ouabain; Peptide Fragments; Protein Conformation; Protein Structure, Tertiary; Sodium-Calcium Exchanger; Troponin T; Zebrafish; Zebrafish Proteins | 2008 |
In vitro antioxidant properties of pentoxifylline and vinpocetine in a rheological model.
Topics: Adult; Blood Viscosity; Caffeine; Calcimycin; Calcium; Egtazic Acid; Erythrocyte Aggregation; Free Radical Scavengers; Hemorheology; Humans; Male; Nifedipine; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Verapamil; Vinca Alkaloids | 2008 |
Intracellular Ca2+ regulation during neuronal differentiation of murine embryonal carcinoma and mesenchymal stem cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blotting, Western; Bone Marrow Cells; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cell Differentiation; Cell Line, Tumor; Cells, Cultured; Embryonal Carcinoma Stem Cells; Gene Expression; Inositol 1,4,5-Trisphosphate Receptors; Intermediate Filament Proteins; Intracellular Space; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Nestin; Neurons; Nifedipine; Reverse Transcriptase Polymerase Chain Reaction; Ryanodine; Ryanodine Receptor Calcium Release Channel; Time Factors | 2010 |
Microbial degradation of pharmaceuticals in estuarine and coastal seawater.
Topics: Absorption; Antipyrine; Bacteria; Biodegradation, Environmental; Caffeine; Carbamazepine; Cotinine; Diltiazem; Ecology; Endocrine Disruptors; Half-Life; New York; Nifedipine; Pharmaceutical Preparations; Seawater; Solubility; Sulfamethoxazole; Trimethoprim; Waste Disposal, Fluid; Water Microbiology; Water Pollutants, Chemical | 2009 |
Pharmacological changes in cellular Ca2+ homeostasis parallel initiation of atrial arrhythmogenesis in murine Langendorff-perfused hearts.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Caffeine; Calcium; Calcium Channel Blockers; Calcium Signaling; Female; Heart; Heart Atria; Homeostasis; Indoles; Male; Mice; Myocytes, Cardiac; Nifedipine; Perfusion; Pharmacological Phenomena | 2009 |
Hypotensive and endothelium-independent vasorelaxant effects of methanolic extract from Curcuma longa L. in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Caffeine; Calcium; Calcium Channel Blockers; Curcuma; Dose-Response Relationship, Drug; Endothelium, Vascular; Ethnopharmacology; In Vitro Techniques; Male; Mesenteric Arteries; Methanol; Nifedipine; Phenylephrine; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Solvents; Vasoconstrictor Agents; Vasodilator Agents | 2009 |
The impact of extracellular and intracellular Ca2+ on ethanol-induced smooth muscle contraction.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Female; Gastric Fundus; Indoles; Isometric Contraction; Male; Mice; Muscle Contraction; Muscle, Smooth; Nifedipine; Ruthenium Red; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Verapamil | 2009 |
Acute atrial arrhythmogenesis in murine hearts following enhanced extracellular Ca(2+) entry depends on intracellular Ca(2+) stores.
Topics: Aniline Compounds; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Caffeine; Calcium; Calcium Channels, L-Type; Calcium Signaling; Heart; Heart Atria; Mice; Myocytes, Cardiac; Nifedipine; Pyrroles; Xanthenes | 2010 |
Calcium transport and homeostasis in gill cells of a freshwater crab Dilocarcinus pagei.
Topics: Amiloride; Animals; Biological Transport; Brachyura; Caffeine; Calcium; Calcium Channel Blockers; Cells, Cultured; Epithelial Cells; Gills; Homeostasis; Kinetics; Nifedipine; Ouabain; Sodium; Sodium-Calcium Exchanger; Thiourea; Vanadates; Verapamil | 2010 |
Cholesterol depletion alters coronary artery myocyte Ca(2+) signalling in a stimulus-specific manner.
Topics: Animals; beta-Cyclodextrins; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Cholesterol; Cholesterol Oxidase; Coronary Vessels; Microscopy, Confocal; Myocytes, Smooth Muscle; Nifedipine; Potassium; Rats; Rats, Wistar | 2010 |
Contribution of sarcoplasmic reticulum Ca²+ release and Ca²+ transporters on sarcolemmal channels to Ca²+ transient in fetal mouse heart.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Fetal Heart; Mice; Myocardial Contraction; Myocytes, Cardiac; Nickel; Nifedipine; Patch-Clamp Techniques; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger | 2011 |
Stable EET urea agonist and soluble epoxide hydrolase inhibitor regulate rat pulmonary arteries through TRPCs.
Topics: Animals; Boron Compounds; Caffeine; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Enzyme Inhibitors; Epoxide Hydrolases; Fatty Acids, Monounsaturated; Female; Imidazoles; Indoles; Lanthanum; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Pulmonary Artery; Rats; Rats, Wistar; Transient Receptor Potential Channels | 2011 |
Store-operated Ca(2+) entry (SOCE) contributes to normal skeletal muscle contractility in young but not in aged skeletal muscle.
Topics: Aging; Anilides; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Electric Stimulation; Excitation Contraction Coupling; Humans; Male; Mice; Muscle Contraction; Muscle, Skeletal; Muscular Atrophy; Naphthalenes; Nickel; Nifedipine; Phosphodiesterase Inhibitors; Pyrones; Thiadiazoles | 2011 |
Development of qualitative and quantitative analysis methods in pharmaceutical application with new selective signal excitation methods for 13 C solid-state nuclear magnetic resonance using 1 H T1rho relaxation time.
Topics: Acetaminophen; Antipyrine; beta-Cyclodextrins; Caffeine; Carbon Isotopes; Chemistry, Pharmaceutical; Crystallization; Drug Combinations; Excipients; Indomethacin; Lactose; Magnetic Resonance Spectroscopy; Nifedipine; Pharmaceutical Preparations; Phenacetin; Povidone; Protons; Pyridones; Signal Processing, Computer-Assisted; Technology, Pharmaceutical | 2013 |
Plasmalemmal sodium-calcium exchanger shapes the calcium and exocytotic signals of chromaffin cells at physiological temperature.
Topics: Animals; Bromides; Caffeine; Calcium Channel Blockers; Calcium Signaling; Catecholamines; Cattle; Cell Membrane; Cells, Cultured; Chromaffin Cells; Exocytosis; Histamine; Kinetics; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; Potassium; Potassium Compounds; Pyrroles; Sodium-Calcium Exchanger; Temperature | 2013 |
Spontaneous, pro-arrhythmic calcium signals disrupt electrical pacing in mouse pulmonary vein sleeve cells.
Topics: Action Potentials; Animals; Atrial Fibrillation; Caffeine; Calcium Signaling; Electric Stimulation; Fluorescence; Lung; Mice; Microscopy, Phase-Contrast; Myocytes, Smooth Muscle; Nifedipine; Pulmonary Veins; Ryanodine; Ryanodine Receptor Calcium Release Channel; Statistics, Nonparametric | 2014 |
Relationship between nitric oxide- and calcium-dependent signal transduction pathways in growth hormone release from dispersed goldfish pituitary cells.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Central Nervous System Stimulants; Enzyme Inhibitors; Gallic Acid; Goldfish; Growth Hormone; Nifedipine; Nitric Oxide; Pituitary Gland; Signal Transduction; Thapsigargin | 2014 |
Store-operated Ca²⁺ entry and depolarization explain the anomalous behaviour of myometrial SR: effects of SERCA inhibition on electrical activity, Ca²⁺ and force.
Topics: Action Potentials; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Carbachol; Cells, Cultured; Cholinergic Agonists; Electric Stimulation; Enzyme Inhibitors; Female; Indoles; Membrane Potentials; Myometrium; Nifedipine; Phosphodiesterase Inhibitors; Pregnancy; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2014 |
Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia.
Topics: Action Potentials; Arrhythmias, Cardiac; Caffeine; Calcium; Cell Differentiation; Ether-A-Go-Go Potassium Channels; Female; Genotype; Humans; Induced Pluripotent Stem Cells; Infant, Newborn; Middle Aged; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Nifedipine; Patch-Clamp Techniques; Phenotype; Polymorphism, Single Nucleotide; Young Adult | 2014 |
Effect of taurine and caffeine on plasma c-reactive protein and calcium in Wistar rats.
Topics: Animals; Biomarkers; C-Reactive Protein; Caffeine; Calcium; Calcium Channel Blockers; Central Nervous System Stimulants; Furosemide; Nifedipine; Rats, Wistar; Sodium Potassium Chloride Symporter Inhibitors; Taurine | 2015 |
A Physiologically Based Pharmacokinetic Model for Pregnant Women to Predict the Pharmacokinetics of Drugs Metabolized Via Several Enzymatic Pathways.
Topics: Caffeine; Cytochrome P-450 Enzyme System; Diazepam; Female; Granisetron; Humans; Metoprolol; Metronidazole; Midazolam; Models, Biological; Nifedipine; Ondansetron; Pharmaceutical Preparations; Pregnancy | 2018 |
Ca
Topics: Animals; Caffeine; Calcium Signaling; Esophageal Sphincter, Lower; Haplorhini; Interstitial Cells of Cajal; Mice; Muscle, Smooth; Nifedipine | 2022 |