Compounds > nifedipine

nifedipine and betaxolol

nifedipine has been researched along with betaxolol in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (12.50)	18.7374
1990's	3 (18.75)	18.2507
2000's	7 (43.75)	29.6817
2010's	4 (25.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Beaumont, K; Di, L; Maurer, TS; Smith, DA	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Canal, M; Carbon, C; Cascio, B; Domart, Y; Flouvat, B; Larribaud, J; Orofiamma, B; Roux, A; Vinceneux, P	1
Angehrn, V; Bättig, B; Beck, G; Graf, A; Hany, S; Jenni, R; Leutenegger, F; Steiner, A; Troesch, M; Willimann, P	1
Abe, I; Fujishima, M; Ohya, Y; Setoguchi, M	1
Friedman, R; Glasser, SP; Smith, LK; Talibi, T; Weir, EK	1
Araie, M; Muta, K	1
Chidlow, G; Cupido, A; Melena, J; Osborne, NN; Wood, JP	1

Reviews

1 review(s) available for nifedipine and betaxolol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

3 trial(s) available for nifedipine and betaxolol

Article	Year
Pharmacokinetic and pharmacodynamic interactions between nifedipine and propranolol or betaxolol. International journal of clinical pharmacology, therapy, and toxicology, 1986, Volume: 24, Issue:3 Topics: Adrenergic beta-Antagonists; Adult; Betaxolol; Blood Pressure; Drug Interactions; Exercise Test; Heart Rate; Humans; Kinetics; Male; Nifedipine; Propanolamines; Propranolol	1986
[Betaxolol versus nifedipine in the treatment of essential hypertension]. Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1988, Oct-11, Volume: 77, Issue:41 Topics: Adrenergic beta-Antagonists; Betaxolol; Blood Pressure; Echocardiography; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Propanolamines	1988
Safety and compatibility of betaxolol hydrochloride combined with diltiazem or nifedipine therapy in stable angina pectoris. The American journal of cardiology, 1994, Feb-01, Volume: 73, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Betaxolol; Chronic Disease; Diltiazem; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Hemodynamics; Humans; Male; Middle Aged; Nifedipine; Physical Exertion; Statistics as Topic; Syncope; Time Factors	1994

Other Studies

12 other study(ies) available for nifedipine and betaxolol

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Volume of Distribution in Drug Design. Journal of medicinal chemistry, 2015, Aug-13, Volume: 58, Issue:15 Topics: Drug Design; Half-Life; Pharmacokinetics	2015
Inhibitory action of betaxolol, a beta 1-selective adrenoceptor antagonist, on voltage-dependent calcium channels in guinea-pig artery and vein. British journal of pharmacology, 1995, Volume: 115, Issue:1 Topics: Animals; Betaxolol; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Electric Conductivity; Female; Guinea Pigs; In Vitro Techniques; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Portal Vein	1995
Effect of long-term topical betaxolol on tissue circulation in the iris and optic nerve head. Experimental eye research, 1997, Volume: 64, Issue:2 Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Betaxolol; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Intraocular Pressure; Iris; Nifedipine; Optic Disk; Rabbits	1997
Topical flunarizine reduces IOP and protects the retina against ischemia-excitotoxicity. Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:5 Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Betaxolol; Calcium; Calcium Channel Blockers; Choline O-Acetyltransferase; Electroretinography; Excitatory Amino Acid Agonists; Flunarizine; Intraocular Pressure; N-Methylaspartate; Neuroprotective Agents; Nifedipine; Parvalbumins; Rabbits; Rats; Rats, Wistar; Reperfusion Injury; Retina; RNA, Messenger; Sodium; Thy-1 Antigens; Vasodilator Agents	2002