nifedipine has been researched along with benidipine hydrochloride in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (76.32) | 18.7374 |
| 1990's | 4 (10.53) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (10.53) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Higo, K; Karasawa, A; Kubo, K | 1 |
| Gotoh, Y; Imaizumi, Y; Watanabe, M; Yamamoto, M | 1 |
| Karasawa, A; Kubo, K | 3 |
| Ikeda, N; Kodama, I; Kubo, K; Toyama, J; Yamada, K; Yoshitake, I | 1 |
| Fuji, Y; Katsumata, H; Nakajima, S; Saruta, T; Suzuki, H | 1 |
| Ishii, A; Nakamizo, N; Nishida, K; Oka, T | 3 |
| Karasawa, A; Kubo, K; Nakamizo, N; Oka, T; Shuto, K | 6 |
| Karasawa, A; Kawato, H; Kubo, K; Kuroda, T; Muto, K; Nakamizo, N | 1 |
| Kawato, H; Kuroda, T; Muto, K; Nakamizo, N; Nishikawa, H | 1 |
| Nakamizo, N; Ono, E; Suzuki, H; Takemoto, Y; Ueno, H | 1 |
| Karasawa, A; Kubo, K; Nakamizo, N; Oka, T | 2 |
| Ikeda, J; Karasawa, A; Kubo, K; Nakamizo, N; Oka, T; Yamada, K | 1 |
| Inoue, A; Kobayashi, H; Kobayashi, S; Nakamizo, N; Oka, T | 2 |
| Akinaga, S; Inoue, A; Kobayashi, H; Kobayashi, S; Nakamizo, N; Oka, T | 1 |
| Inoue, A; Kobayashi, H; Kobayashi, S; Nakamizo, N; Nishiie, H; Ohishi, T; Oka, T | 2 |
| Inoue, A; Kobayashi, H; Kobayashi, S; Kosaka, Y; Nakamizo, N; Oka, T; Okumura, S | 1 |
| Kobayashi, H; Kobayashi, S; Lenau, H; Maier-Lenz, H; Oka, T; Rode, H; Thieme, G; Wölke, E | 1 |
| Kitamura, K; Kuriyama, H; Nakao, K; Okabe, K; Terada, K | 1 |
| Ikeda, N; Kodama, I; Nezasa, Y; Toyama, J; Yamada, K; Yoshitake, I | 1 |
| Deguchi, T; Hara, T; Hattori, O; Kato, Y; Saijyo, T; Suzuki, K; Tanaka, H | 1 |
| Choi, H; Choi, NY; Joo Lee, Y; Koh, SH; Lee, EH; Lee, KY; Park, HH; Yu, HJ | 1 |
| Alba Soto, CD; Bellera, CL; Carrillo, C; Fraccaroli, L; Larocca, L; Sbaraglini, ML; Talevi, A | 1 |
| Hosaka, S; Tokunaga, Y | 1 |
| Bai, JY; Cui, N; Dai, K; Deng, F; Fang, YJ; Hu, YY; Li, H; Li, SF; Liu, W; Lu, QB; Peng, K; Wan, WW; Wang, ZB; Xiao, GF; Xin, QL; Yuan, C; Zhang, LK; Zhang, PH; Zhang, SF; Zhang, YL; Zhu, XT | 1 |
| Arslan, YK; Cakir, T; Suleyman, H; Sunar, M; Yazici, GN; Yucetas, SC | 1 |
1 trial(s) available for nifedipine and benidipine hydrochloride
| Article | Year |
|---|---|
Benidipine hydrochloride--a new calcium-channel blocker of the dihydropyridine type. Pharmacokinetics, pharmacodynamics, tolerance and dose finding in mild to moderate hypertension.
Topics: Adult; Antihypertensive Agents; Biological Availability; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Drug Tolerance; Heart Rate; Humans; Hypertension; Male; Nifedipine; Posture; Pulse | 1988 |
37 other study(ies) available for nifedipine and benidipine hydrochloride
| Article | Year |
|---|---|
Protective effects of benidipine hydrochloride (KW-3049), a calcium antagonist, against experimental arterial calcinosis and endothelial dysfunction in rats.
Topics: Acetylcholine; Animals; Aorta; Arteries; Calcinosis; Calcium; Calcium Channel Blockers; Endothelium, Vascular; Ergocalciferols; Male; Microscopy, Electron, Scanning; Muscle Relaxation; Muscle, Smooth, Vascular; Nicotine; Nifedipine; Rats; Rats, Inbred Strains | 1992 |
Mechanisms of long-lasting effects of benidipine on Ca current in guinea-pig ventricular cells.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Evoked Potentials; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardium; Nerve Block; Nifedipine; Substance Withdrawal Syndrome | 1990 |
Protection by benidipine hydrochloride (KW-3049), a calcium antagonist, of ischemic kidney in rats via inhibitions of Ca-overload, ATP-decline and lipid peroxidation.
Topics: Adenosine Triphosphate; Animals; Blood Urea Nitrogen; Calcium; Calcium Channel Blockers; Creatinine; Ischemia; Lipid Peroxidation; Male; Nifedipine; Rats; Rats, Inbred Strains; Renal Circulation | 1990 |
[Electrophysiological effects of KW-3049, a new dihydropyridine type Ca antagonist, on isolated rabbit hearts, sinus nodal tissues and guinea-pig ventricular muscles].
Topics: Animals; Bundle of His; Calcium Channel Blockers; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Ion Channels; Isoproterenol; Nifedipine; Papillary Muscles; Rabbits; Sinoatrial Node; Verapamil | 1986 |
Hormonal and renal responses to oral once-daily calcium entry blocker in normotensive and hypertensive persons.
Topics: Adult; Aldosterone; Angiotensin II; Calcium Channel Blockers; Dopamine; Epinephrine; Female; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Nifedipine; Norepinephrine; Renin | 1988 |
Receptor binding properties of the new calcium antagonist benidipine hydrochloride.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Guinea Pigs; Nifedipine; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Nicotinic; Regression Analysis | 1988 |
Antihypertensive effects of the new calcium antagonist benidipine hydrochloride in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Heart Rate; Hydralazine; Hypertension; Male; Nicardipine; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Renin; Urination | 1988 |
Benidipine hydrochloride (KW-3049): a new dihydropyridine calcium antagonist.
Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Humans; Nifedipine | 1988 |
Synthesis and pharmacological activity of stereoisomers of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine-dicarboxylic acid methyl 1-(phenylmethyl)-3-piperidinyl ester.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Crystallization; Dose-Response Relationship, Drug; Guinea Pigs; Heart Rate; Isomerism; Male; Mice; Molecular Structure; Nifedipine; Rats; Rats, Inbred SHR | 1988 |
Synthesis of expected metabolites of benidipine hydrochloride.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Molecular Structure; Nifedipine | 1988 |
Physico-chemical properties and stabilities of the highly potent calcium antagonist benidipine hydrochloride.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Differential Thermal Analysis; Drug Stability; Hot Temperature; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Molecular Weight; Nifedipine; Solubility; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thermogravimetry; X-Ray Diffraction | 1988 |
Slow dissociation of the new slow-onset and long-acting calcium antagonist benidipine hydrochloride from 3H-nitrendipine binding sites.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Male; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred Strains | 1988 |
Antihypertensive effects of intravenous administration of benidipine hydrochloride and some other calcium antagonists in conscious, spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Injections, Intravenous; Male; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred SHR; Verapamil | 1988 |
Antihypertensive effects of the new calcium antagonist benidipine hydrochloride in conscious, renal-hypertensive dogs.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dogs; Female; Heart Rate; Hypertension, Renal; Male; Nicardipine; Nifedipine; Nitrendipine; Propranolol | 1988 |
Effects of benidipine hydrochloride on atrioventricular conduction time and postural reflex in gallamine-immobilized cats.
Topics: Animals; Antihypertensive Agents; Atrioventricular Node; Blood Pressure; Calcium Channel Blockers; Cats; Diltiazem; Dose-Response Relationship, Drug; Gallamine Triethiodide; Heart Conduction System; Heart Rate; Hypotension, Orthostatic; Immobilization; Nifedipine; Phenoxybenzamine; Posture; Verapamil | 1988 |
Antianginal effects of the new calcium antagonist benidipine hydrochloride in anesthetized rats and spontaneously hypertensive rats. Electrocardiographic study.
Topics: Angina Pectoris; Animals; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Electrocardiography; Heart Rate; Hydralazine; Isoproterenol; Male; Nifedipine; Propranolol; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Vasopressins | 1988 |
Vasodilating effects of the new calcium antagonist benidipine hydrochloride in anesthetized dogs and cats.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Cats; Cerebral Cortex; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intra-Arterial; Injections, Intravenous; Male; Nicardipine; Nifedipine; Papaverine; Vasodilation; Vasodilator Agents | 1988 |
Effects of the new calcium antagonist benidipine hydrochloride on cardiohemodynamics in anesthetized dogs.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Dogs; Female; Heart Rate; Male; Nifedipine; Stroke Volume | 1988 |
Beneficial effects of the new calcium antagonist benidipine hydrochloride on myocardial dysfunction following coronary occlusion and reperfusion in anesthetized dogs.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Coronary Disease; Dogs; Electrocardiography; Female; Heart Rate; Male; Myocardial Reperfusion; Nifedipine; Stroke Volume | 1988 |
Pharmacological actions of benidipine hydrochloride in several isolated smooth muscles and myocardium.
Topics: Animals; Calcium Channel Blockers; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart; Male; Mesenteric Arteries; Molecular Structure; Muscle, Smooth; Nifedipine; Rabbits; Rats; Rats, Inbred Strains | 1988 |
Gas chromatographic method for the quantification of the new calcium antagonist benidipine hydrochloride in plasma using electron capture detection.
Topics: Animals; Calcium Channel Blockers; Chromatography, Gas; Chromatography, High Pressure Liquid; Nifedipine; Oxidation-Reduction; Rats | 1988 |
Sensitive radioreceptor assay of the calcium antagonist benidipine hydrochloride in plasma and urine.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Dogs; Male; Molecular Structure; Nifedipine; Nitrendipine; Radioligand Assay; Rats; Regression Analysis | 1988 |
Determination of the calcium antagonist benidipine hydrochloride in plasma by sensitive radioimmunoassay.
Topics: Animals; Antibody Formation; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Cross Reactions; Immune Sera; Male; Nifedipine; Rabbits; Radioimmunoassay; Rats; Regression Analysis | 1988 |
Absorption, distribution and excretion after oral administration of 14C-benidipine hydrochloride in rats and dogs.
Topics: Administration, Oral; Animals; Autoradiography; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dogs; Half-Life; Intestinal Absorption; Male; Nifedipine; Rats; Tissue Distribution | 1988 |
Absorption, distribution and excretion of 14C-benidipine hydrochloride after repeated administration to rats.
Topics: Administration, Oral; Animals; Calcium Channel Blockers; Feces; Intestinal Absorption; Male; Nifedipine; Rats; Tissue Distribution | 1988 |
Pharmacokinetic study of benidipine hydrochloride in rats and dogs.
Topics: Administration, Oral; Animals; Biological Availability; Calcium Channel Blockers; Dogs; Female; Half-Life; Injections, Intravenous; Intestinal Absorption; Male; Nifedipine; Oxidation-Reduction; Rats; Rats, Inbred Strains; Tissue Distribution | 1988 |
Identification of benidipine hydrochloride metabolites in rats and dogs.
Topics: Animals; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dogs; Hydrolysis; Male; Molecular Structure; Nifedipine; Oxidation-Reduction; Rats; Rats, Inbred Strains; Scintillation Counting | 1988 |
Inhibitory effect of KW-3049, a new 1,4-dihydropyridine calcium antagonist, on the reduction of myocardial creatine kinase activity and high-energy phosphate content in rats subjected to coronary artery ligation.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Coronary Circulation; Creatine Kinase; Ligation; Male; Methacrylates; Myocardial Infarction; Myocardium; Nifedipine; Phosphates; Phosphocreatine; Propranolol; Rats; Rats, Inbred Strains; Sulfonamides | 1988 |
Calcium antagonistic effects and the in vitro duration of actions of KW-3049, a new 1,4-dihydropyridine derivative, in isolated canine coronary arteries.
Topics: Animals; Calcium Channel Blockers; Calcium Radioisotopes; Coronary Vessels; Dogs; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Nifedipine; Vasodilator Agents | 1988 |
Action of the 1,4-dihydropyridine derivative, KW-3049, on the smooth muscle membrane of the rabbit mesenteric artery.
Topics: Action Potentials; Animals; Barium; Calcium Channel Blockers; In Vitro Techniques; Membrane Potentials; Mesenteric Arteries; Microelectrodes; Muscle, Smooth, Vascular; Nifedipine; Rabbits | 1987 |
Effects of KW-3049, a newly developed calcium antagonist, on rabbit sinus nodes and guinea pig ventricular muscles.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Electrophysiology; Guinea Pigs; Membrane Potentials; Muscles; Nifedipine; Rabbits; Sinoatrial Node; Ventricular Function | 1987 |
Effect of the new calcium antagonist (+/-)-(R*)-3-[(R*)-1-benzyl-3- piperidyl] methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5- pyridinedicarboxylate hydrochloride (KW-3049) on cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; DNA; Heart Rate; Hypertension; Male; Myocardium; Nicardipine; Nifedipine; Organ Size; Propranolol; Rats; Rats, Inbred SHR; Renin; RNA | 1993 |
Neuroprotective effects of amlodipine besylate and benidipine hydrochloride on oxidative stress-injured neural stem cells.
Topics: Amlodipine; Animals; Apoptosis; Calcium Channel Blockers; Cell Proliferation; Cell Survival; Cells, Cultured; Mitogen-Activated Protein Kinase 3; Neural Stem Cells; Neuroprotective Agents; Nifedipine; Oxidative Stress; Phosphatidylinositol 3-Kinase; Rats; Rats, Sprague-Dawley; Signal Transduction | 2014 |
Novel cruzipain inhibitors for the chemotherapy of chronic Chagas disease.
Topics: Adult; Animals; Antiprotozoal Agents; Chagas Disease; Chronic Disease; Clofazimine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Disease Models, Animal; Drug Therapy; Humans; Male; Mice, Inbred C3H; Muscles; Nifedipine; Parasite Load; Protozoan Proteins; Trypanosoma cruzi | 2016 |
Differences in Powder Properties of Two 1,4-Dihydropyridine-Type Compounds Evaluated through Thermal Analysis.
Topics: Calorimetry, Differential Scanning; Compressive Strength; Dihydropyridines; Lactose; Nifedipine; Nitrobenzenes; Piperazines; Stearic Acids; Tablets; Temperature | 2017 |
Calcium channel blockers reduce severe fever with thrombocytopenia syndrome virus (SFTSV) related fatality.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Chlorocebus aethiops; Disease Models, Animal; Female; Humans; Mice; Mice, Inbred C57BL; Nifedipine; Phlebotomus Fever; Phlebovirus; Retrospective Studies; RNA Interference; RNA, Small Interfering; Vero Cells; Viral Load; Virus Replication | 2019 |
Effects of Benidipine Hydrochloride on Ischemia Reperfusion Injury of Rat Brain.
Topics: Animals; Brain; Brain Ischemia; Male; Neuroprotective Agents; Nifedipine; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury | 2021 |