nifedipine and benazepril

nifedipine has been researched along with benazepril in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (36.36)18.2507
2000's3 (27.27)29.6817
2010's4 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Sun, H1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bellet, M; Degen, P; Glaus, L; Graf, P; Jakobsen, J; Maurice, NP; Ménard, J1
Bellet, M; Bodin, F; Ménard, J; Serrurier, D; Tanner, K; Whalen, JJ1
Criscione, L; Dohi, Y; Lüscher, TF; Pfeiffer, K1
Crozier, IG; Foy, SG; Horsburgh, RJ; Ikram, H; Khurmi, NS; Low, CJ; Richards, AM; Shirlaw, TM1
Feng, Z; Messerli, FH; Oparil, S1
Faulkner, M; Hilleman, DE; Reyes, AP; Wurdeman, RL1

Reviews

2 review(s) available for nifedipine and benazepril

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Use of crossover trials to obtain antihypertensive dose-response curves and to study combination therapy during the development of benazepril.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1990, Volume: 8, Issue:4

    Topics: Antihypertensive Agents; Benzazepines; Blood Pressure; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Enalapril; Humans; Hypertension; Nifedipine

1990

Trials

3 trial(s) available for nifedipine and benazepril

ArticleYear
Unmasking of the hypotensive effect of nifedipine in normotensives by addition of the angiotensin converting enzyme inhibitor benazepril.
    Journal of hypertension, 1992, Volume: 10, Issue:9

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Blood Pressure; Delayed-Action Preparations; Drug Interactions; Heart Rate; Humans; Male; Nifedipine; Reference Values; Renin; Renin-Angiotensin System

1992
Angiotensin converting enzyme inhibition in chronic stable angina: effects on myocardial ischaemia and comparison with nifedipine.
    British heart journal, 1994, Volume: 71, Issue:1

    Topics: Adult; Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Chronic Disease; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Electrocardiography, Ambulatory; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Nifedipine

1994
Comparison of efficacy and side effects of combination therapy of angiotensin-converting enzyme inhibitor (benazepril) with calcium antagonist (either nifedipine or amlodipine) versus high-dose calcium antagonist monotherapy for systemic hypertension.
    The American journal of cardiology, 2000, Dec-01, Volume: 86, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Single-Blind Method

2000

Other Studies

6 other study(ies) available for nifedipine and benazepril

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.
    Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2

    Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction

2012
Angiotensin blockade or calcium antagonists improve endothelial dysfunction in hypertension: studies in perfused mesenteric resistance arteries.
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:3

    Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Disease Models, Animal; Endothelins; Endothelium, Vascular; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium Chloride; Pyrimidines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles; Vascular Resistance

1994
Efficacy and safety of a therapeutic interchange from high-dose calcium channel blockers to a fixed-dose combination of amlodipine/benazepril in patients with moderate-to-severe hypertension.
    Journal of human hypertension, 2001, Volume: 15, Issue:8

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Blood Pressure; Calcium Channel Blockers; Costs and Cost Analysis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Treatment Outcome

2001