nifedipine has been researched along with antipyrine in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (14.29) | 18.7374 |
| 1990's | 7 (25.00) | 18.2507 |
| 2000's | 10 (35.71) | 29.6817 |
| 2010's | 7 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Anan'ev, EA; Grek, OR; Kolpakov, MA; Sharapov, VI | 1 |
| Desager, JP; Harvengt, C; Horsmans, Y; Pauwels, S | 1 |
| Edeki, T; Johnston, A; Turner, P | 1 |
| Adebayo, GI; Mabadeje, AF | 1 |
| Fujishiro, N; Kawata, H | 1 |
| Breimer, DD; Brugman, M; Schellens, JH; van der Wart, JH | 1 |
| Abernethy, DR; Dickinson, TH; Egan, JM | 1 |
| Bauer, LA; Davis, R; Greene, L; Horn, JR; Opheim, K; Stenwall, M | 1 |
| Bliesath, H; Hartmann, M; Huber, R; Radtke, HW; Steinijans, VW; Wurst, W; Zech, K | 1 |
| Lanchote, VL; Ping, WC; Santos, SR | 1 |
| Grek, OR; Sharapov, VI | 1 |
| Kokue, E; Saitoh, T; Shimoda, M | 1 |
| Benotti, MJ; Brownawell, BJ | 1 |
| Mimura, H; Nasu, M; Nemoto, T; Sako, K | 1 |
1 review(s) available for nifedipine and antipyrine
| Article | Year |
|---|---|
Lack of pantoprazole drug interactions in man.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absorption; Antipyrine; Benzimidazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 Enzyme System; Diazepam; Digoxin; Drug Interactions; Female; Humans; Liver; Longitudinal Studies; Male; Nifedipine; Omeprazole; Pantoprazole; Phenytoin; Proton Pump Inhibitors; Sulfoxides; Theophylline; Tissue Distribution; Warfarin | 1994 |
5 trial(s) available for nifedipine and antipyrine
| Article | Year |
|---|---|
Effect of nifedipine on antipyrine and theophylline disposition.
Topics: Adult; Antipyrine; Drug Interactions; Female; Humans; Male; Microsomes, Liver; Nifedipine; Premedication; Randomized Controlled Trials as Topic; Theophylline | 1990 |
Effects of nifedipine on hepatic drug oxidation.
Topics: Adult; Antipyrine; Cytochrome P-450 Enzyme System; Female; Half-Life; Humans; Liver; Male; Mixed Function Oxygenases; Nifedipine; Oxidation-Reduction; Pharmaceutical Preparations; Smoking | 1988 |
Changes in antipyrine and indocyanine green kinetics during nifedipine, verapamil, and diltiazem therapy.
Topics: Adult; Antipyrine; Benzazepines; Biological Availability; Diltiazem; Drug Interactions; Female; Humans; Indocyanine Green; Kinetics; Liver; Male; Metabolic Clearance Rate; Nifedipine; Random Allocation; Verapamil | 1986 |
Lack of pantoprazole drug interactions in man.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absorption; Antipyrine; Benzimidazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 Enzyme System; Diazepam; Digoxin; Drug Interactions; Female; Humans; Liver; Longitudinal Studies; Male; Nifedipine; Omeprazole; Pantoprazole; Phenytoin; Proton Pump Inhibitors; Sulfoxides; Theophylline; Tissue Distribution; Warfarin | 1994 |
Influence of renal failure on cytochrome P450 activity in hypertensive patients using a "cocktail" of antipyrine and nifedipine.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Antipyrine; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Drug Combinations; Female; Half-Life; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Nifedipine | 1996 |
23 other study(ies) available for nifedipine and antipyrine
| Article | Year |
|---|---|
ElogPoct: a tool for lipophilicity determination in drug discovery.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
[Pharmacokinetics of antipyrine, nifedipine and diazepam in experimental myocardial infarct].
Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Diazepam; Hydroxylation; Male; Microsomes, Liver; Myocardial Infarction; Nifedipine; Rats; Rats, Wistar; Time Factors | 1992 |
Lack of effect by nifedipine on hepatic mixed function oxidase in man.
Topics: Adult; Antipyrine; Cytochrome P-450 Enzyme System; Humans; Liver; Male; Mixed Function Oxygenases; Nifedipine | 1991 |
An examination of a possible pharmacokinetic interaction between nifedipine and antipyrine.
Topics: Administration, Oral; Adult; Antipyrine; Chromatography, High Pressure Liquid; Drug Interactions; Female; Humans; Male; Nifedipine; Saliva | 1990 |
Twitch potentiation of frog (Rana japonica) skeletal muscle by antipyrine.
Topics: Action Potentials; Animals; Antipyrine; Calcium; Membrane Potentials; Microelectrodes; Muscle Contraction; Muscles; Nifedipine; Ranidae; Sarcoplasmic Reticulum; Verapamil | 1989 |
Influence of enzyme induction and inhibition on the oxidation of nifedipine, sparteine, mephenytoin and antipyrine in humans as assessed by a "cocktail" study design.
Topics: Adult; Antipyrine; Cimetidine; Enzyme Induction; Female; Humans; Hydantoins; Male; Mephenytoin; Metabolic Clearance Rate; Nifedipine; Oxidation-Reduction; Phenobarbital; Smoking; Sparteine | 1989 |
[Activity of liver monooxygenase system in rats with low and high resistance to hypoxia].
Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Cytochromes b5; Diazepam; Hypoxia; Male; Microsomes, Liver; Mixed Function Oxygenases; Nifedipine; Rats; Rats, Wistar; Species Specificity | 1996 |
The impact of acute phase response on the plasma clearance of antipyrine, theophylline, phenytoin and nifedipine in rabbits.
Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antipyrine; Area Under Curve; Chromatography, High Pressure Liquid; Escherichia coli; Female; Half-Life; Injections, Intramuscular; Interleukin-6; Lipopolysaccharides; Metabolic Clearance Rate; Nifedipine; Phenytoin; Protein Binding; Rabbits; Theophylline; Vasodilator Agents | 2000 |
Microbial degradation of pharmaceuticals in estuarine and coastal seawater.
Topics: Absorption; Antipyrine; Bacteria; Biodegradation, Environmental; Caffeine; Carbamazepine; Cotinine; Diltiazem; Ecology; Endocrine Disruptors; Half-Life; New York; Nifedipine; Pharmaceutical Preparations; Seawater; Solubility; Sulfamethoxazole; Trimethoprim; Waste Disposal, Fluid; Water Microbiology; Water Pollutants, Chemical | 2009 |
Development of qualitative and quantitative analysis methods in pharmaceutical application with new selective signal excitation methods for 13 C solid-state nuclear magnetic resonance using 1 H T1rho relaxation time.
Topics: Acetaminophen; Antipyrine; beta-Cyclodextrins; Caffeine; Carbon Isotopes; Chemistry, Pharmaceutical; Crystallization; Drug Combinations; Excipients; Indomethacin; Lactose; Magnetic Resonance Spectroscopy; Nifedipine; Pharmaceutical Preparations; Phenacetin; Povidone; Protons; Pyridones; Signal Processing, Computer-Assisted; Technology, Pharmaceutical | 2013 |