nifedipine and alprostadil

nifedipine has been researched along with alprostadil in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199012 (31.58)18.7374
1990's15 (39.47)18.2507
2000's5 (13.16)29.6817
2010's6 (15.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Shimada, SG; Stitt, JT1
Kimblad, PO; Massa, G; Sjöberg, T; Solem, JO; Steen, S1
McLean, R; Pearl, RG; Prielipp, RC; Rosenthal, MH1
Finn, JC; Pearl, RG1
Francis, GS; Johnson, GJ; Leis, LA1
Müller, B; Schmidtke, M1
Müller, B; Schmidtke, M; Witt, W1
Nagao, I; Ogawa, K; Oida, A; Tsukada, K; Yoshimura, M1
Broughton Pipkin, F; Chinnery, E1
Bühler, FR; Erne, P; Resink, TJ1
Pearl, RG; Prielipp, RC; Rosenthal, MH1
Ikegami, K; Ueda, S; Yano, S; Yoshida, M1
Goldberg, HS; Halpern, SM; Jasper, AC; Koerner, SK; Lehrman, S; Shah, PK1
Fujihira, T; Fukuchi, Y; Imaizumi, T; Ishii, N; Kuroiwa, A; Miyahara, K; Nakashima, Y; Takasugi, M1
Fujii, I; Handa, S; Nakamura, Y; Ohonishi, S; Yamazaki, H1
Connolly, SM1
Ito, T; Kai, I; Ogawa, K1
Kawashima, A; Koike, H; Nishio, S; Ueno, Y1
Hibi, M; Iwase, J; Kawamura, M; Murakami, F; Usui, A; Yoshida, K1
Kimblad, PO; Steen, S1
Parizi, M; Rayan, GM; Tomasek, JJ1
Castillo Palma, MJ; Sánchez-Román, J; Talegón Meléndez, A; Varela-Aguilar, JM1
Kojima, M; Miyakawa, T; Ui, M1
Oonishi, T; Sakashita, K; Uyesaka, N1
LoCicero, J; McCully, JD; Sasaki, S; Yasuda, K2
Artemiou, O; Bîrsan, T; Klepetko, W; Kranz, A; Mares, P; Taghavi, S; Zuckermann, A1
Kurumatani, H; Matsushita, T; Tamura, M1
Akimaru, S; Ito, H; Katsube, N; Maegawa, H; Marsala, M; Nakai, K; Takenobu, Y; Takimizu, H1
Chan, KM; Hidaka, H; Hung, GH; Jones, RL; Lam, FF; Sasaki, Y; Suzuki, M1
De Lisle, RC1
Demir, B; Engin, MS; Keleş, MK; Küçüker, İ; Yosma, E1

Reviews

1 review(s) available for nifedipine and alprostadil

ArticleYear
Scleroderma: therapeutic options.
    Cutis, 1984, Volume: 34, Issue:3

    Topics: Alprostadil; Captopril; Colchicine; Griseofulvin; Humans; Immunosuppressive Agents; Nifedipine; Penicillamine; Phenytoin; Physical Therapy Modalities; Plasmapheresis; Prostaglandins E; Scleroderma, Systemic; Vasodilator Agents

1984

Trials

1 trial(s) available for nifedipine and alprostadil

ArticleYear
[Comparative study of misoprostol and nifedipine in the treatment of Raynaud's phenomenon secondary to systemic diseases. Hemodynamic assessment with Doppler duplex].
    Revista clinica espanola, 1997, Volume: 197, Issue:2

    Topics: Adult; Aged; Alprostadil; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Misoprostol; Nifedipine; Raynaud Disease; Regional Blood Flow

1997

Other Studies

36 other study(ies) available for nifedipine and alprostadil

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Calcium channel blockers inhibit endogenous pyrogen fever in rats and rabbits.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 71, Issue:3

    Topics: Alprostadil; Animals; Body Temperature; Brain; Calcium Channel Blockers; Fever; Interleukin-1; Male; Microinjections; Nifedipine; Pyrogens; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Stereotaxic Techniques; Verapamil

1991
High potassium contents in organ preservation solutions cause strong pulmonary vasocontraction.
    The Annals of thoracic surgery, 1991, Volume: 52, Issue:3

    Topics: Alprostadil; Animals; Dose-Response Relationship, Drug; Hypertonic Solutions; Isotonic Solutions; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Organ Preservation; Potassium; Pulmonary Artery; Solutions; Swine

1991
Hemodynamic profiles of prostaglandin E1, isoproterenol, prostacyclin, and nifedipine in experimental porcine pulmonary hypertension.
    Critical care medicine, 1991, Volume: 19, Issue:1

    Topics: Alprostadil; Animals; Blood Pressure; Cardiac Output; Epoprostenol; Heart Rate; Hemodynamics; Hypertension, Pulmonary; Isoproterenol; Nifedipine; Pulmonary Artery; Swine; Vascular Resistance; Vasodilator Agents

1991
Hemodynamic effects of diltiazem during vasoconstrictor pulmonary hypertension in sheep.
    Anesthesia and analgesia, 1990, Volume: 71, Issue:5

    Topics: Alprostadil; Animals; Diltiazem; Hemodynamics; Hypertension, Pulmonary; Male; Nifedipine; Sheep; Vasodilator Agents

1990
Adenosine potentiates the inhibitory effects of calcium channel antagonists on human platelet aggregation induced by thromboxane A2 or U46619.
    Thrombosis research, 1990, Jul-01, Volume: 59, Issue:1

    Topics: Adenosine; Alprostadil; Calcium Channel Blockers; Diltiazem; Drug Synergism; Epinephrine; Humans; In Vitro Techniques; Nifedipine; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2; Verapamil

1990
Microvascular effects of iloprost in the hamster cheek pouch.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17A

    Topics: Alprostadil; Animals; Capillary Permeability; Cheek; Cricetinae; Epoprostenol; Iloprost; Male; Mesocricetus; Microcirculation; Nifedipine; Vasodilation

1987
Action of the stable prostacyclin analogue iloprost on microvascular tone and -permeability in the hamster cheek pouch.
    Prostaglandins, leukotrienes, and medicine, 1987, Volume: 29, Issue:2-3

    Topics: Alprostadil; Animals; Blood Pressure; Capillary Permeability; Cricetinae; Dose-Response Relationship, Drug; Epoprostenol; Iloprost; Male; Mesocricetus; Microcirculation; Mouth Mucosa; Muscle Tonus; Nifedipine; Permeability; Platelet Aggregation; SRS-A

1987
[A case of primary pulmonary hypertension with beneficial effect of oral long-acting prostaglandin E1 and nifedipine].
    Kokyu to junkan. Respiration & circulation, 1989, Volume: 37, Issue:11

    Topics: Administration, Oral; Adult; Alprostadil; Delayed-Action Preparations; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension, Pulmonary; Nifedipine; Prognosis

1989
The effect of a calcium antagonist, nitrendipine, on the responses of isolated strips of human, chorionic plate artery to prostaglandins E2 and E1.
    British journal of pharmacology, 1985, Volume: 86, Issue:3

    Topics: Alprostadil; Arteries; Calcium Channel Blockers; Cesarean Section; Chorion; Dinoprostone; Female; Humans; In Vitro Techniques; Nifedipine; Nitrendipine; Pregnancy; Prostaglandins E; Random Allocation; Vasoconstriction

1985
The influence of CGP 28392, a 1,4-dihydropyridine, on human platelet calcium and cyclic AMP metabolism.
    European journal of pharmacology, 1985, Jul-31, Volume: 113, Issue:3

    Topics: Alprostadil; Blood Platelets; Calcium; Calcium Channel Blockers; Cyclic AMP; Humans; In Vitro Techniques; Kinetics; Nifedipine; Nitrendipine; Phosphorylation; Protein Kinases; Pyridines

1985
Hemodynamic profiles of prostaglandin E1, isoproterenol, prostacyclin, and nifedipine in vasoconstrictor pulmonary hypertension in sheep.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:8

    Topics: Alprostadil; Animals; Drug Evaluation, Preclinical; Epoprostenol; Hemodynamics; Hypertension, Pulmonary; Isoproterenol; Lung; Nifedipine; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Sheep; Vasodilation

1988
Effects of prostaglandins on the isolated human minor calyx.
    Urologia internationalis, 1986, Volume: 41, Issue:3

    Topics: Alprostadil; Calcium; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Female; Humans; In Vitro Techniques; Kidney Calices; Kidney Pelvis; Male; Muscle Contraction; Nifedipine; Prostaglandins; Prostaglandins E; Prostaglandins F

1986
Prostaglandin E1 as a screening vasodilator in primary pulmonary hypertension.
    Chest, 1987, Volume: 92, Issue:4

    Topics: Adult; Aged; Alprostadil; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Male; Middle Aged; Nifedipine; Oxygen; Pulmonary Circulation; Pulmonary Gas Exchange; Vasodilator Agents

1987
Autopsy findings of the coronary arteries of variant angina with Raynaud's phenomenon of the tongue.
    Japanese heart journal, 1986, Volume: 27, Issue:1

    Topics: Adult; Alprostadil; Angina Pectoris, Variant; Cardiac Catheterization; Coronary Vessels; Drug Therapy, Combination; Electrocardiography; Humans; Isosorbide Dinitrate; Male; Nicardipine; Nifedipine; Raynaud Disease; Tongue Diseases; Valsalva Maneuver

1986
Strategy to manage pump failure due to chronic pulmonary diseases--pathophysiology and treatment of right ventricular overload.
    Japanese circulation journal, 1986, Volume: 50, Issue:4

    Topics: Alprostadil; Echocardiography; Heart; Heart Diseases; Heart Ventricles; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Nifedipine; Oxygen; Pulmonary Circulation; Stroke Volume; Vascular Resistance; Vasodilator Agents

1986
Effects of peripheral vasodilation caused by verapamil, nifedipine, and nitroglycerin on plasma prostaglandins and thromboxane concentrations.
    Japanese heart journal, 1982, Volume: 23, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Alprostadil; Animals; Dinoprost; Dogs; Female; Male; Nifedipine; Nitroglycerin; Prostaglandins; Prostaglandins E; Prostaglandins F; Pyridines; Thromboxane B2; Thromboxanes; Vascular Resistance; Vasodilation; Verapamil

1982
Effect of beraprost sodium, a stable prostacyclin analogue, on pulmonary thromboembolism in mice.
    Thrombosis research, 1995, Jan-15, Volume: 77, Issue:2

    Topics: Administration, Oral; Alprostadil; Animals; Aspirin; Bridged Bicyclo Compounds; Collagen; Diltiazem; Drug Evaluation, Preclinical; Epinephrine; Epoprostenol; Fatty Acids, Monounsaturated; Fibrinolytic Agents; Heparin; Hydralazine; Injections, Intravenous; Isosorbide Dinitrate; Male; Mice; Nifedipine; Nitroprusside; Platelet Aggregation Inhibitors; Pulmonary Embolism; Superoxide Dismutase; Vasodilator Agents

1995
The effects of calcium antagonists and prostaglandin E1 on isolated canine coronary arterial tension.
    Surgery today, 1994, Volume: 24, Issue:12

    Topics: Alprostadil; Animals; Calcium; Calcium Channel Blockers; Coronary Vessels; Data Interpretation, Statistical; Diltiazem; Dogs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Potassium; Sodium; Solutions; Verapamil

1994
Eliminating the strong pulmonary vasoconstriction caused by Euro-Collins solution.
    The Annals of thoracic surgery, 1994, Volume: 58, Issue:3

    Topics: Alprostadil; Animals; Constriction, Pathologic; Drug Combinations; Drug Interactions; Endothelium, Vascular; Epoprostenol; Hypertonic Solutions; Models, Biological; Nifedipine; Papaverine; Phenylacetates; Pulmonary Artery; Severity of Illness Index; Sulfonamides; Swine; Thromboxane A2; Thromboxanes; Vasoconstriction; Vasodilator Agents

1994
Pharmacologic regulation of Dupuytren's fibroblast contraction in vitro.
    The Journal of hand surgery, 1996, Volume: 21, Issue:6

    Topics: Alprostadil; Angiotensin II; Calcium Channel Blockers; Dinoprost; Dinoprostone; Dupuytren Contracture; Fibroblasts; Humans; In Vitro Techniques; Lysophospholipids; Muscle Contraction; Nifedipine; Serotonin; Verapamil

1996
Differential routes of Ca2+ influx in Swiss 3T3 fibroblasts in response to receptor stimulation.
    The Biochemical journal, 1998, Jan-01, Volume: 329 ( Pt 1)

    Topics: 3T3 Cells; Alprostadil; Angiotensin II; Animals; Arachidonic Acid; Bombesin; Bradykinin; Calcium; Calcium Channel Blockers; Diltiazem; Endothelins; Enzyme Activation; GTP-Binding Proteins; Inositol Phosphates; Mice; Nifedipine; Pertussis Toxin; Phospholipases A; Phospholipases A2; Platelet-Derived Growth Factor; Protein Kinase C; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Vasopressins; Virulence Factors, Bordetella

1998
Regulation of red blood cell filterability by Ca2+ influx and cAMP-mediated signaling pathways.
    The American journal of physiology, 1997, Volume: 273, Issue:6

    Topics: Adult; Alprostadil; Calcium; Calcium Channel Blockers; Cyclic AMP; Dinoprostone; Epinephrine; Erythrocyte Deformability; Erythrocytes; Felodipine; Filtration; Humans; In Vitro Techniques; Kinetics; Male; Nifedipine; Pentoxifylline; Signal Transduction; Stress, Mechanical

1997
Calcium channel blocker enhances lung preservation.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1999, Volume: 18, Issue:2

    Topics: Adenosine; Airway Resistance; Allopurinol; Alprostadil; Animals; Calcium Channel Blockers; Glutathione; Insulin; Lung Compliance; Lung Transplantation; Male; Nifedipine; Organ Preservation Solutions; Oxygen; Potassium; Pulmonary Gas Exchange; Raffinose; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasoconstriction; Vasodilator Agents

1999
Does PGE1 attenuate potassium-induced vasoconstriction in initial pulmonary artery flush on lung preservation?
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1999, Volume: 18, Issue:2

    Topics: Alprostadil; Animals; Calcium Channel Blockers; Injections, Intra-Arterial; Lung; Lung Transplantation; Male; Nifedipine; Organ Preservation; Organ Preservation Solutions; Potassium; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Ryanodine; Vasoconstriction; Vasodilator Agents

1999
Transient left ventricular failure following bilateral lung transplantation for pulmonary hypertension.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1999, Volume: 18, Issue:4

    Topics: Adult; Alprostadil; Antihypertensive Agents; Cardiac Output, Low; Cardiotonic Agents; Catheterization, Swan-Ganz; Clonidine; Dobutamine; Echocardiography; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Transplantation; Male; Nifedipine; Respiratory Insufficiency; Treatment Outcome; Vasodilator Agents; Ventricular Dysfunction, Left

1999
Comparative effects of beraprost, a stable analogue of prostacyclin, with PGE(1), nitroglycerin and nifedipine on canine model of vasoconstrictive pulmonary hypertension.
    Prostaglandins, leukotrienes, and essential fatty acids, 2001, Volume: 64, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Animals; Antihypertensive Agents; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Epoprostenol; Humans; Hypertension, Pulmonary; Male; Nifedipine; Nitroglycerin; Oxygen; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents

2001
Effects of OP-1206 alpha-CD on walking dysfunction in the rat neuropathic intermittent claudication model: comparison with nifedipine, ticlopidine and cilostazol.
    Prostaglandins & other lipid mediators, 2003, Volume: 71, Issue:3-4

    Topics: Alprostadil; Animals; Body Weight; Cilostazol; Disease Models, Animal; Exercise Test; Intermittent Claudication; Male; Nifedipine; Platelet Aggregation; Rats; Rats, Wistar; Skin; Spinal Cord; Tetrazoles; Ticlopidine; Time Factors; Walking

2003
Investigation of the pronounced synergism between prostaglandin E2 and other constrictor agents on rat femoral artery.
    Prostaglandins, leukotrienes, and essential fatty acids, 2006, Volume: 74, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Animals; Dinoprostone; Drug Interactions; Drug Synergism; Femoral Artery; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Nifedipine; Phenylephrine; Potassium; Prostaglandins F, Synthetic; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP3 Subtype; rho-Associated Kinases; Sensitivity and Specificity; Sulfonamides; Vasoconstrictor Agents

2006
Lubiprostone stimulates small intestinal mucin release.
    BMC gastroenterology, 2012, Nov-06, Volume: 12

    Topics: Alprostadil; Animals; Indomethacin; Intestine, Small; Lubiprostone; Male; Mice; Mice, Inbred C57BL; Mucins; Muscle, Smooth; Nifedipine

2012
Comparison of the effects of different vasoactive and antiplatelet drugs on perforator flap viability. An experimental study.
    Hand surgery & rehabilitation, 2016, Volume: 35, Issue:1

    Topics: Alprostadil; Animals; Arteries; Epigastric Arteries; Graft Survival; Hydralazine; Nifedipine; Perforator Flap; Piracetam; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Vasodilator Agents

2016