nifedipine has been researched along with allopurinol in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (13.64) | 18.7374 |
| 1990's | 14 (31.82) | 18.2507 |
| 2000's | 12 (27.27) | 29.6817 |
| 2010's | 12 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Dalipram, RA; Dusting, GJ; Sobey, CG; Woodman, OL | 1 |
| Hirano, T; Kozaki, M; Oka, K; Tamaki, T; Toyoshima, Y | 1 |
| Oyanagui, Y; Sato, S | 1 |
| Ahrén, B; Ar'Rajab, A; Bengmark, S | 1 |
| Fryer, PR; Green, CJ; Pickford, MA; Sarathchandra, P | 1 |
| Masumoto, N; Miyake, A; Tanizawa, O; Tasaka, K | 1 |
| Orimo, H; Ouchi, Y | 1 |
| Tiegs, G; Wendel, A; Wolter, M | 1 |
| Robak, J; Shridi, F | 1 |
| Bratell, S; Folmerz, P; Hansson, R; Jonsson, O; Lundstam, S; Pettersson, S; Rippe, B; Scherstén, T | 1 |
| Burghardt, B; Janero, DR; Lopez, R | 1 |
| Blaser, KU; Lämmle, B | 1 |
| Downey, JM; Hearse, DJ; Yellon, DM | 1 |
| Cervini, C; Core, P; Grassi, W; Muti, S; Serretti, R | 1 |
| Belton, NR; Dyer, JJ; Ellis, JA; McIntosh, N | 1 |
| Li, B; Li, P; Zhou, W | 1 |
| Hayashi, S; Kimura, M; Maeda, K | 1 |
| Abboud, FM; Bielefeldt, K; Conklin, JL; Sharma, RV; Whiteis, CA | 1 |
| Busse, R; Fisslthaler, B; Marumo, T; Schini-Kerth, VB | 1 |
| LoCicero, J; McCully, JD; Sasaki, S; Yasuda, K | 1 |
| Janssen, LJ; Netherton, SJ; Walters, DK | 1 |
1 review(s) available for nifedipine and allopurinol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for nifedipine and allopurinol
| Article | Year |
|---|---|
Protective effects of nifedipine and allopurinol on high energy shock wave induced acute changes of renal function.
Topics: Adolescent; Adult; Allopurinol; Female; Humans; Kidney Calculi; Kidney Diseases; Kidney Function Tests; Kidney Pelvis; Lithotripsy; Male; Middle Aged; Nifedipine; Prospective Studies | 1995 |
42 other study(ies) available for nifedipine and allopurinol
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogPoct: a tool for lipophilicity determination in drug discovery.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Impaired endothelium-dependent relaxation of dog coronary arteries after myocardial ischaemia and reperfusion: prevention by amlodipine, propranolol and allopurinol.
Topics: Acetylcholine; Allopurinol; Amlodipine; Animals; Calcium Channel Blockers; Coronary Disease; Coronary Vessels; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Reperfusion Injury; Nifedipine; Nitroglycerin; Propranolol | 1992 |
Promotion of lymphocyte blastogenesis by hemodialysate of chronic renal failure.
Topics: Allopurinol; Anabolic Agents; Androstanols; Calcitriol; Cells, Cultured; Concanavalin A; Creatinine; DNA Replication; Female; Furosemide; Humans; Kidney Failure, Chronic; Lectins; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; Nifedipine; Reference Values; Renal Dialysis; Thymidine; Time Factors | 1992 |
Inhibition by nilvadipine of ischemic and carrageenan paw edema as well as of superoxide radical production from neutrophils and xanthine oxidase.
Topics: Animals; Calcimycin; Carrageenan; Edema; Free Radicals; Ischemia; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred Strains; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nifedipine; Rats; Rats, Inbred Strains; Superoxides; Tetradecanoylphorbol Acetate; Xanthine Oxidase | 1991 |
Improved liver preservation for transplantation due to calcium channel blockade.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine; Allopurinol; Animals; Calcium Channel Blockers; Glutathione; Insulin; Liver; Liver Transplantation; Nifedipine; Organ Preservation; Organ Preservation Solutions; Rabbits; Raffinose; Solutions; Verapamil | 1991 |
Ultrastructural changes in rat lungs after 48 h cold storage with and without reperfusion.
Topics: Allopurinol; Animals; Basement Membrane; Cryopreservation; Deferoxamine; Endothelium, Vascular; Epoprostenol; Lung; Lung Transplantation; Microscopy, Electron; Nifedipine; Organ Preservation; Rats; Rats, Inbred Strains; Reperfusion Injury; Time Factors; Verapamil | 1990 |
Superoxide anion increases intracellular free calcium in human myometrial cells.
Topics: Calcium; Cells, Cultured; Desmin; Female; Fluorescent Antibody Technique; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Myometrium; Myosins; Nifedipine; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1990 |
The role of calcium and magnesium in the development of atherosclerosis. Experimental and clinical evidence.
Topics: Animals; Arteriosclerosis; Calcium; Cells, Cultured; DNA; Epidermal Growth Factor; Female; Guinea Pigs; Humans; Lipoproteins, LDL; Magnesium; Male; Middle Aged; Nifedipine; Platelet-Derived Growth Factor; Rabbits; Xanthine Oxidase | 1990 |
Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice.
Topics: Allopurinol; Animals; Chemical and Drug Induced Liver Injury; Eicosanoic Acids; Endotoxins; Epoprostenol; Galactosamine; Iloprost; Imidazoles; Male; Mice; Mice, Inbred Strains; Nifedipine; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Verapamil; Xanthine Oxidase | 1989 |
The influence of calcium channel blockers on superoxide anions.
Topics: Animals; Anions; Calcium Channel Blockers; Diltiazem; Fendiline; Free Radicals; In Vitro Techniques; Microsomes, Liver; Nifedipine; Oxidation-Reduction; Rats; Superoxides; Verapamil; Xanthine Oxidase | 1988 |
Effects of oxygen free radical scavengers, xanthine oxidase inhibition and calcium entry-blockers on leakage of albumin after ischaemia. An experimental study in rabbit kidneys.
Topics: Allopurinol; Animals; Calcium Channel Blockers; Capillary Permeability; Catalase; Felodipine; Free Radicals; Ischemia; Kidney; Mannitol; Nifedipine; Nitrendipine; Oxygen; Rabbits; Serum Albumin, Radio-Iodinated; Superoxide Dismutase; Xanthine Oxidase | 1988 |
Protection of cardiac membrane phospholipid against oxidative injury by calcium antagonists.
Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Heart; In Vitro Techniques; Lipid Peroxides; Male; Membrane Lipids; Myocardium; Nifedipine; Phospholipids; Rats; Verapamil; Xanthine Oxidase | 1988 |
[Acute hyperkalemia and non-oliguric kidney failure during treatment with indomethacin, allopurinol, nifedipine, hydrochlorothiazide/amiloride, trimethoprim/sulfamethoxazole and acetylsalicylic acid].
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Allopurinol; Amiloride; Aspirin; Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hyperkalemia; Indomethacin; Male; Nifedipine; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1988 |
Myocardial infarct size limitation. Principles, problems and possibilities.
Topics: Allopurinol; Animals; Coronary Circulation; Dogs; Flurbiprofen; Humans; Metoprolol; Myocardial Infarction; Nifedipine; Tetrazolium Salts; Verapamil | 1984 |
Influence of nifedipine on plasma membrane fluidity and oxidative burst of polymorphonuclear leucocytes.
Topics: Fluorescence Polarization; Humans; In Vitro Techniques; Luminescent Measurements; Lymphocytes; Membrane Fluidity; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nifedipine; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate; Xanthine Oxidase | 1995 |
The effects of hypoxia and drugs on intracellular calcium in neonatal neutrophils.
Topics: Allopurinol; Asphyxia Neonatorum; Calcium; Cell Hypoxia; Dexamethasone; Humans; In Vitro Techniques; Infant, Newborn; Intracellular Fluid; Neutrophils; Nifedipine | 1994 |
Cellular mechanism of U78517F in the protection of porcine coronary artery endothelial cells from oxygen radical-induced damage.
Topics: Animals; Antioxidants; Calcium; Cell Survival; Chromans; Coronary Vessels; Endothelium, Vascular; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; L-Lactate Dehydrogenase; Lipid Peroxidation; Malondialdehyde; Muscle, Smooth, Vascular; Nifedipine; Oxidation-Reduction; Oxygen; Piperazines; Swine; Xanthine Oxidase; Xanthines | 1993 |
Reactive oxygen species and calcium homeostasis in cultured human intestinal smooth muscle cells.
Topics: Acetylcholine; Cadmium; Calcium; Calcium Channel Blockers; Cell Survival; Cells, Cultured; Homeostasis; Humans; Hydrogen Peroxide; Inositol 1,4,5-Trisphosphate; Intestines; Kinetics; Membrane Potentials; Muscle, Smooth; Nifedipine; Patch-Clamp Techniques; Potassium; Reactive Oxygen Species; Verapamil; Xanthine; Xanthine Oxidase; Xanthines | 1997 |
Platelet-derived growth factor-stimulated superoxide anion production modulates activation of transcription factor NF-kappaB and expression of monocyte chemoattractant protein 1 in human aortic smooth muscle cells.
Topics: Allopurinol; Androstadienes; Aorta, Thoracic; Becaplermin; Biphenyl Compounds; Cells, Cultured; Chemokine CCL2; Enzyme Inhibitors; Humans; Indoles; Interleukin-1; Multienzyme Complexes; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Oxidases; NF-kappa B; Nifedipine; Onium Compounds; Phosphoinositide-3 Kinase Inhibitors; Platelet-Derived Growth Factor; Protein Kinase C; Proto-Oncogene Proteins c-sis; RNA, Messenger; Superoxide Dismutase; Superoxides; Transcription, Genetic; Wortmannin | 1997 |
Calcium channel blocker enhances lung preservation.
Topics: Adenosine; Airway Resistance; Allopurinol; Alprostadil; Animals; Calcium Channel Blockers; Glutathione; Insulin; Lung Compliance; Lung Transplantation; Male; Nifedipine; Organ Preservation Solutions; Oxygen; Potassium; Pulmonary Gas Exchange; Raffinose; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasoconstriction; Vasodilator Agents | 1999 |
Ca(2+)-dependent K(+) channels and Na(+)-K(+)-ATPase mediate H(2)O(2)- and superoxide-induced relaxations in canine trachealis.
Topics: Animals; Calcium; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; In Vitro Techniques; Membrane Potentials; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Nifedipine; Ouabain; Potassium Channels; Sodium-Potassium-Exchanging ATPase; Superoxides; Tetraethylammonium; Thiourea; Trachea; Xanthine; Xanthine Oxidase | 2000 |