nifedipine and acetylcysteine

nifedipine has been researched along with acetylcysteine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (50.00)29.6817
2010's8 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
de Los Ríos, C; Egea, J; Gálvez, E; García, AG; Iriepa, I; León, R; López, MG; Marco-Contelles, J; Moraleda, I; Romero, A; Samadi, A; Villarroya, M1
Ekins, S; Williams, AJ; Xu, JJ1
Bharate, SS; Vishwakarma, RA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Meng, F; Tian, H; Zhang, G; Zhang, Q1
Li, H; Tian, H; Zhang, G; Zhang, Q1
Abe, R; Inagaki, Y; Kikuchi, S; Sasaki, N; Takeuchi, M; Yamagishi, S1
Kijne, JW; Memelink, J; Pauw, B; van Duijn, B1
Arai, Y; Arakawa, M; Ishige, K; Ishimura, A; Ito, Y; Kawabe, K; Suzuki, S1
Aronstam, RS; Chen, DR; Huang, CC; Huang, YW1

Reviews

1 review(s) available for nifedipine and acetylcysteine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

15 other study(ies) available for nifedipine and acetylcysteine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives.
    Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Calcium; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytotoxins; Electron Transport Chain Complex Proteins; Electrophorus; Glucose; Hippocampus; Humans; Isomerism; Models, Molecular; Naphthyridines; Neuroprotective Agents; Okadaic Acid; Oligomycins; Oxygen; Peptide Fragments; Protein Binding; Protein Phosphatase 2; Rats; Rotenone; Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics

2015
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Biphasic activation of apoptosis signal-regulating kinase 1-stress-activated protein kinase 1-c-Jun N-terminal protein kinase pathway is selectively mediated by Ca2+-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors involving oxidat
    Neuroscience letters, 2003, Jan-30, Volume: 337, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Brain Ischemia; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Enzyme Activation; Hippocampus; Ion Channel Gating; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase Kinase 5; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Nifedipine; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spermine

2003
Antioxidant NAC and AMPA/KA receptor antagonist DNQX inhibited JNK3 activation following global ischemia in rat hippocampus.
    Neuroscience research, 2003, Volume: 46, Issue:2

    Topics: Acetylcysteine; Animals; Brain Ischemia; Calcium Channel Blockers; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Immunoblotting; Ketamine; Male; Mitogen-Activated Protein Kinase 10; Mitogen-Activated Protein Kinases; Nifedipine; Protein Transport; Protein-Tyrosine Kinases; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Time Factors

2003
Nifedipine inhibits apoptotic cell death of cultured endothelial cells induced by tumor necrosis factor-alpha.
    Drugs under experimental and clinical research, 2003, Volume: 29, Issue:4

    Topics: Acetylcysteine; Apoptosis; Calcium Channel Blockers; Cell Count; Cell Survival; Cells, Cultured; Endothelial Cells; Free Radical Scavengers; Humans; Nifedipine; Tumor Necrosis Factor-alpha

2003
Activation of the oxidative burst by yeast elicitor in Catharanthus roseus cells occurs independently of the activation of genes involved in alkaloid biosynthesis.
    Plant molecular biology, 2004, Volume: 55, Issue:6

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Ascorbic Acid; Blotting, Northern; Calcium; Catharanthus; Cells, Cultured; Culture Media; Gadolinium; Gene Expression Regulation, Plant; Lanthanum; Models, Biological; Nifedipine; Phosphorylation; Reactive Oxygen Species; RNA, Plant; Secologanin Tryptamine Alkaloids; Yeasts

2004
N-Acetylcysteine and ebselen but not nifedipine protected cerebellar granule neurons against 4-hydroxynonenal-induced neuronal death.
    Neuroscience research, 2007, Volume: 57, Issue:2

    Topics: Acetylcysteine; Aldehydes; Animals; Animals, Newborn; Azoles; Calcium; Cell Death; Cells, Cultured; Cerebellum; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Glutathione; Isoindoles; Membrane Potential, Mitochondrial; Neurons; Neuroprotective Agents; Nifedipine; Organoselenium Compounds; Rats; Rats, Wistar; Reactive Oxygen Species; Time Factors

2007
Oxidative stress, calcium homeostasis, and altered gene expression in human lung epithelial cells exposed to ZnO nanoparticles.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:1

    Topics: Acetylcysteine; Calcium; Calcium Channel Blockers; Cell Line; Cell Membrane; Cell Survival; Dose-Response Relationship, Drug; Epithelial Cells; Free Radical Scavengers; Gene Expression; Homeostasis; Humans; L-Lactate Dehydrogenase; Lung; Nanoparticles; Nifedipine; Oxidative Stress; Reactive Oxygen Species; Zinc Oxide

2010