nifedipine has been researched along with 4-aminopyridine in 99 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (10.10) | 18.7374 |
| 1990's | 45 (45.45) | 18.2507 |
| 2000's | 29 (29.29) | 29.6817 |
| 2010's | 15 (15.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Aiyar, J; Auperin, DD; Chandy, KG; Grissmer, S; Gutman, GA; Hanson, DC; Karmilowicz, MJ; Mather, RJ; Nguyen, AN | 1 |
| Brandriff, B; Cahalan, M; Chandy, G; Chandy, KG; Copeland, NG; Dukes, ID; Gutman, GA; Hustad, CM; Jenkins, NA; Kalman, K; Mohrenweiser, H; Nguyen, A; Tseng-Crank, J | 1 |
| Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Sen, S; Sinha, N | 1 |
| Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Al-Sabi, A; Daly, D; Dolly, JO; Herron, C; Hoefer, P; Kaza, SK; Kinsella, GK; Metais, C; Nolan, K; Pickering, M | 1 |
| Kaneda, M; Kaneko, A; Ueda, Y | 1 |
| Sanders, KM; Thornbury, KD; Ward, SM | 1 |
| Deitmer, P; Lammel, E; Noack, T | 1 |
| Delbono, O; Kotsias, BA | 1 |
| Liu, LX; Ram, JL | 1 |
| Amédée, T; Dupouy, B; Ellie, E; Vincent, JD | 1 |
| Dourado, MM; Dryer, SE; Wisgirda, ME | 1 |
| Furukawa, T; Katsuragi, T; Ogawa, S; Shirakabe, K; Soejima, O | 1 |
| Mantovani, P; Palmi, M; Petkov, VV; Sgaragli, GP | 1 |
| Furukawa, T; Katsuragi, T; Usune, S | 1 |
| Bonnet, P; Harder, DR; Rusch, NJ | 1 |
| Msghina, M; Stjärne, E; Stjärne, L | 1 |
| Alvarado, R; Fragoso-Veloz, J; Massieu, L; Tapia, R | 1 |
| Kato, A; Nakamura, F; Sugimoto, T; Sumino, S; Tomaru, T; Uchida, Y | 1 |
| Sugimoto, T; Uchida, Y | 1 |
| Massieu, L; Tapia, R | 1 |
| Botana, L; Eleno, N; Espinosa, J | 1 |
| Savage, AO | 1 |
| Uchida, Y | 1 |
| Sonoki, H; Sugimoto, T; Tomaru, T; Uchida, Y | 1 |
| Chiarandini, DJ; Stefani, E | 1 |
| Mitchell, MR; Powell, T; Terrar, DA; Twist, VW | 1 |
| Bonev, AD; Mawe, GM; Nelson, MT; Zhang, L | 1 |
| Brouard, A; Lhiaubet, AM; Pelaprat, D; Rostène, W; Vial, M | 1 |
| Bilodeau, L; Durroux, T; Gallo-Payet, N; Guillon, G; Payet, MD | 1 |
| Li, L; Wu, HS; Xu, JH | 1 |
| Akbarali, HI; Goyal, RK; Hatakeyama, N; Wang, Q | 1 |
| Asano, M; Shibasaki, K; Takenaka, T; Uchida, W | 1 |
| Cognard, C; Constantin, B; Raymond, G; Rivet-Bastide, M | 1 |
| Ginkawa, M; Kontani, H; Sakai, T | 1 |
| Katina, IE; Lukyanenko, V; Nasledov, GA | 1 |
| Basavappa, S; Brammer, M; Campbell, I; Laro, D; Mangel, AW; Romano-Silva, MA | 1 |
| Cahill, AL; Perlman, RL | 1 |
| Clausen, C; Goligorsky, MS; Gordienko, DV | 1 |
| Bayliss, DA; Berger, AJ; Viana, F | 1 |
| Bywater, RA; Lang, RJ; Taylor, GS; Vogalis, F | 1 |
| Lee, HK; Sanders, KM | 1 |
| Hume, RI; Lin, X; Nuttall, AL | 1 |
| Katina, IE; Lukyanenko, V; Nasledov, GA; Terentyev, DA | 1 |
| Gean, PW; Huang, CC; Wang, SJ | 1 |
| Hu, Q; Huang, F; Shi, Y | 1 |
| Maggi, CA; Santicioli, P | 1 |
| Carvajal, A; Dueñas, A; Fernández de la Gándara, F; Maroto, M; Nieto, A; Velasco, A | 1 |
| Barbeito, L; Frizzo, ME | 1 |
| Buus, C; Mulvany, MJ; Nilsson, H; Prieto, D | 1 |
| Cotton, KD; Hollywood, MA; McHale, NG; Thornbury, KD | 1 |
| Arai, Y; Asano, M; Okazaki, T; Shibasaki, K; Takenaka, T; Uchida, W | 1 |
| Boyett, MR; Harrison, SM; Janvier, NC; McMorn, SO; Taggart, P | 1 |
| Myers, AC | 1 |
| Bolotina, VM; Cohen, RA; Mongayt, DA; Zakharov, SI | 1 |
| Strata, F | 1 |
| Beirão, PS; Cordeiro, MN; Cruz, JS; Diniz, CR; Gomez, MV; Kalapothakis, E; Kushmerick, C; Penaforte, CL; Prado, MA; Prado, VF; Romano-Silva, MA | 1 |
| Smith, GT; Zakon, HH | 1 |
| Jung, MW; Kang, GH; Kang, YS; Kim, JA; Lee, SH; Lee, YS | 1 |
| French, AS; Sekizawa, SI; Torkkeli, PH | 1 |
| Jones, MB; Odblom, MP; Williamson, R | 1 |
| Blandizzi, C; Colucci, R; Del Tacca, M; Tognetti, M | 1 |
| De Graan, PN; Gispen, WH; Pasinelli, P; Ramakers, GM; van Beest, M; van der Slot, A | 1 |
| Cheek, ER; Fast, VG; Ideker, RE | 1 |
| Miller, DV; Paterson, WG; Zhang, Y | 1 |
| Malvin, GM; Walker, BR | 1 |
| Kane, KA; Rankin, AC; Workman, AJ | 1 |
| Cook, A; Franks, CJ; Holden-Dye, L; Pemberton, D; Vinogradova, I; Walker, RJ | 1 |
| Flameng, W; Macianskiene, R; Moccia, F; Mubagwa, K; Sipido, KR | 1 |
| Nedergaard, OA; Uhrenholt, TR | 1 |
| Faizi, M; Janahmadi, M; Mahmoudian, M | 1 |
| Pan, YP; Wang, XL; Xu, XH | 1 |
| Chang, IY; Choi, S; Jun, JY; Kim, KW; Kim, MJ; Kim, MY; Kong, ID; Lee, KP; Park, CK; So, I; Yeum, CH; You, HJ | 1 |
| Exintaris, B; Lang, RJ; Mulholland, E | 1 |
| Deng, X; Lau, CP; Li, GR; Sun, H | 1 |
| Cogolludo, A; Lodi, F; Moreno, L; Perez-Vizcaino, F; Tamargo, J | 1 |
| Cho, CH; Hui, MK; Lam, EK; Li, GR; Li, P; Luo, JC; Shin, VY; Tai, EK; Wong, HP; Wu, WK; Yang, YH; Ye, YN | 1 |
| Collins, A; Ishmael, JE; Larson, MK; Pfaff, JE | 1 |
| Cacciani, F; Salvarani, N; Zaniboni, M | 1 |
| Kito, Y; Suzuki, H | 1 |
| Cho, CH; Li, GR; Wang, JY; Wong, TM; Wu, WK; Yu, L | 1 |
| Kitano, H; Shinohara, H; Zakir Hossain, SM | 1 |
| Baker, PN; Fyfe, GK; Greenwood, SL; Sibley, CP; Williams, JL | 1 |
| Basak, F; Cehreli, SB; Cehreli, ZC; Guven, G; Kaya, E; Seyrek, M; Ulku, C; Vural, IM; Yildiz, O | 1 |
| Bányász, T; Bárándi, L; Harmati, G; Horváth, B; Magyar, J; Nánási, PP; Szentandrássy, N; Varró, A | 1 |
| Ali, DW; Chang, JP; Yu, Y | 1 |
| Balezina, OP; Bogatcheva, PO; Ezhova, EV | 1 |
| Centurión, D; Cobos-Puc, LE; González-Hernández, A; Maassenvandenbrink, A; Muñoz-Islas, E; Ramírez-Rosas, MB; Sánchez-López, A; Villalón, CM | 1 |
| Cehreli, ZC; Guven, G; Seyrek, M; Vural, IM; Yildiz, O | 1 |
| Khaertdinov, NN; Sitdikova, GF; Zefirov, AL | 1 |
| Bauriedl, J; Bussek, A; Lohmann, H; Ravens, U; Schmidt, M; Wettwer, E | 1 |
| Coquinco, A; Craig, AM; Cynader, M; Kaufman, AM; Lee, H; Milnerwood, AJ; Raymond, LA; Sepers, MD; She, K; Wang, L | 1 |
| Chen, JD; Li, S; Maude-Griffin, R; Pullan, AJ | 1 |
| Bae, YM; Cho, H; Kim, B; Kim, JG; Noh, HJ; Park, SW; Sung, DJ | 1 |
| Chen, YH; Fei, YD; Hou, JW; Li, W; Li, YG; Wang, Q; Wang, YP | 1 |
99 other study(ies) available for nifedipine and 4-aminopyridine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
Topics: 3T3 Cells; Animals; Base Sequence; Benzopyrans; Capsaicin; Cell Line; Cells, Cultured; Charybdotoxin; Cloning, Molecular; Cromakalim; Diltiazem; Diterpenes; Elapid Venoms; Flecainide; Ion Channel Gating; Mice; Molecular Sequence Data; Nifedipine; Oligodeoxyribonucleotides; Peptides; Potassium Channels; Pyrroles; Scorpion Venoms; Sotalol | 1994 |
Genomic organization, chromosomal localization, tissue distribution, and biophysical characterization of a novel mammalian Shaker-related voltage-gated potassium channel, Kv1.7.
Topics: Amino Acid Sequence; Animals; Base Sequence; Chromosome Mapping; Chromosomes; Cloning, Molecular; Electrophysiology; Humans; In Situ Hybridization; Ion Channel Gating; Islets of Langerhans; Mice; Mice, Inbred Strains; Molecular Sequence Data; Neurotoxins; Phylogeny; Potassium Channels; Sequence Analysis, DNA; Shaker Superfamily of Potassium Channels | 1998 |
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.
Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain | 2016 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
A Rational Design of a Selective Inhibitor for Kv1.1 Channels Prevalent in Demyelinated Nerves That Improves Their Impaired Axonal Conduction.
Topics: Animals; Cell Line; Corpus Callosum; Demyelinating Diseases; Drug Design; Humans; Kv1.1 Potassium Channel; Male; Mice, Inbred C57BL; Molecular Docking Simulation; Potassium Channel Blockers; Pyrroles | 2017 |
Voltage-dependent ionic currents in solitary horizontal cells isolated from cat retina.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Action Potentials; Animals; Calcium Channels; Cats; Cells, Cultured; Cesium; Electric Conductivity; Membrane Potentials; Nifedipine; Potassium Channels; Retinal Ganglion Cells; Sodium; Sodium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1992 |
Outward currents in longitudinal colonic muscle cells contribute to spiking electrical behavior.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Action Potentials; Animals; Calcium; Colon; Dogs; Electrophysiology; Female; Male; Muscle, Smooth; Nifedipine; Tetraethylammonium; Tetraethylammonium Compounds | 1992 |
Characterization of membrane currents in single smooth muscle cells from the guinea-pig gastric antrum.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Animals; Caffeine; Calcium; Guinea Pigs; In Vitro Techniques; Kinetics; Membrane Potentials; Muscle, Smooth; Nifedipine; Potassium; Pyloric Antrum; Tetraethylammonium; Tetraethylammonium Compounds | 1992 |
Calcium action potentials in innervated and denervated rat muscle fibres.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Animals; Apamin; Cadmium; Calcium; Calcium Channels; Electric Conductivity; Muscle Denervation; Muscles; Nifedipine; Rats; Rats, Inbred Strains; Tetraethylammonium; Tetraethylammonium Compounds | 1991 |
Voltage-dependent calcium current in dissociated smooth muscle cells of the buccal mass of Aplysia.
Topics: 4-Aminopyridine; Animals; Aplysia; Biological Transport; Calcium; Calcium Channels; Cell Separation; Cesium; Electric Stimulation; Muscle Contraction; Muscle, Smooth; Nifedipine; Tetraethylammonium; Tetraethylammonium Compounds | 1991 |
Voltage-dependent calcium and potassium channels in Schwann cells cultured from dorsal root ganglia of the mouse.
Topics: 4-Aminopyridine; Animals; Barium; Calcium Channels; Cells, Cultured; Cobalt; Dose-Response Relationship, Drug; Ganglia, Spinal; Membrane Potentials; Mice; Nifedipine; Potassium Channels; Schwann Cells; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1991 |
Properties of Ca2+ currents in acutely dissociated neurons of the chick ciliary ganglion: inhibition by somatostatin-14 and somatostatin-28.
Topics: 4-Aminopyridine; Acetylcholine; Action Potentials; Animals; Calcium; Calcium Channels; Cells, Cultured; Chick Embryo; Ganglia, Parasympathetic; GTP-Binding Proteins; Ion Channel Gating; Neurons; Nifedipine; Pertussis Toxin; Potassium; Potassium Channels; Somatostatin; Somatostatin-28; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Virulence Factors, Bordetella | 1991 |
Involvement of dihydropyridine-sensitive Ca2+ channels in adenosine-evoked inhibition of acetylcholine release from guinea pig ileal preparation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Acetylcholine; Adenosine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Calcium Channels; Chromatography, High Pressure Liquid; Dihydropyridines; Electric Stimulation; Guinea Pigs; Ileum; Male; Muscle, Smooth; Nifedipine; Physostigmine; Tetrodotoxin; Theophylline | 1990 |
4-Aminopyridine activates an inhibitory alpha 1-adrenergic mechanism unmasked by nifedipin on the electrically stimulated rat vas deferens.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Animals; Calcium; Electric Stimulation; Epididymis; In Vitro Techniques; Male; Muscle, Smooth; Nifedipine; Potassium Channels; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens | 1990 |
Involvement of K(+)-channel opening in endothelin-1 induced suppression of spontaneous contractions in the guinea pig taenia coli.
Topics: 4-Aminopyridine; Action Potentials; Animals; Apamin; Calcium; Colon; Endothelins; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Nifedipine; Potassium Channels | 1991 |
Characterization of an outward K+ current in freshly dispersed cerebral arterial muscle cells.
Topics: 4-Aminopyridine; Animals; Calcium; Cats; Cerebral Arteries; Electric Conductivity; Electric Stimulation; Female; Hydrogen-Ion Concentration; Male; Muscle, Smooth, Vascular; Nifedipine; Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds | 1991 |
K+ and Ca2+ channel blocking agents increase or decrease stimulus-evoked but not spontaneous quantal transmitter release in sympathetic nerve terminals.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Triphosphate; Animals; Cadmium; Calcium Channel Blockers; Drug Combinations; Electric Stimulation; In Vitro Techniques; Male; Mice; Nerve Endings; Neuromuscular Junction; Nifedipine; Potassium Channels; Sympathetic Nervous System; Synaptic Transmission; Tetraethylammonium Compounds; Vas Deferens | 1990 |
Seizures and wet-dog shakes induced by 4-aminopyridine, and their potentiation by nifedipine.
Topics: 4-Aminopyridine; Animals; Behavior, Animal; Drug Synergism; Electroencephalography; Hippocampus; Male; Microinjections; Nifedipine; Rats; Rats, Inbred Strains; Seizures | 1990 |
Phasic contractions of canine and human coronary arteries induced by potassium channel blockers.
Topics: 4-Aminopyridine; Adult; Aged; Amifampridine; Aminopyridines; Angina Pectoris, Variant; Animals; Arteries; Coronary Vasospasm; Coronary Vessels; Dogs; Female; Humans; Ion Channels; Macaca mulatta; Male; Middle Aged; Models, Biological; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Swine; Tetraethylammonium Compounds; Vasoconstriction | 1986 |
The effects of nicorandil on phasic contractions of isolated canine coronary artery.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calmodulin; Coronary Vessels; Dogs; Ergonovine; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Vasodilator Agents | 1987 |
Relationship of dihydropyridine binding sites with calcium-dependent neurotransmitter release in synaptosomes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Aminopyridines; Animals; Brain; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; gamma-Aminobutyric Acid; Ion Channels; Isradipine; Lanthanum; Male; Mice; Neurotransmitter Agents; Nifedipine; Nitrendipine; Oxadiazoles; Potassium; Receptors, Nicotinic; Ruthenium Red; Synaptosomes | 1988 |
Dual effect of dihydropyridines on 45Ca uptake induced by the K+ -channel blocker, 4-aminopyridin on mast cells.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Dihydropyridines; Female; Histamine Release; Ion Channels; Mast Cells; Nifedipine; Nisoldipine; Potassium; Rats; Rats, Inbred Strains | 1988 |
A comparison of the effects of 4-dimethylaminopyridine and 4-aminopyridine on isolated cardiac and skeletal muscle preparations.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Diaphragm; Female; Gallopamil; Guinea Pigs; Heart Atria; Hydroxydopamines; In Vitro Techniques; Male; Muscle Contraction; Myocardial Contraction; Neuromuscular Junction; Nifedipine; Norepinephrine; Oxidopamine; Rats; Reserpine; Synaptic Transmission; Tubocurarine | 1985 |
Decreasing potassium conductance--a possible mechanism of phasic coronary vasospasm.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; Coronary Vasospasm; Coronary Vessels; Dogs; Ergonovine; Female; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Macaca mulatta; Male; Membrane Potentials; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardium; Niacinamide; Nicorandil; Nifedipine; Potassium; Swine; Tetraethylammonium; Tetraethylammonium Compounds | 1985 |
[Effects of 3,4-diaminopyridine on the contractions of guinea-pig tracheal smooth muscle induced by histamine and prostaglandin D2].
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Drug Synergism; Guinea Pigs; Histamine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nifedipine; Prostaglandin D2; Prostaglandins D; Tetrodotoxin; Trachea | 1988 |
Calcium action potentials in rat fast-twitch and slow-twitch muscle fibres.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Barium; Calcium; Chlorides; Electric Conductivity; In Vitro Techniques; Ion Channels; Muscles; Nifedipine; Potassium; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds; Time Factors | 1983 |
Strontium, nifedipine and 4-aminopyridine modify the time course of the action potential in cells from rat ventricular muscle.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Heart Ventricles; In Vitro Techniques; Myocardial Contraction; Nifedipine; Rats; Rats, Inbred Strains; Strontium; Time Factors | 1984 |
Ionic basis of the action potential of guinea pig gallbladder smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Action Potentials; Animals; Calcium Channels; Cell Membrane; Charybdotoxin; Electrophysiology; Female; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth; Nifedipine; Potassium Channel Blockers; Potassium Channels; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1993 |
Effects of ion channel blockers and phorbol ester treatments on [3H]dopamine release and neurotensin facilitation of [3H]dopamine release from rat mesencephalic cells in primary culture.
Topics: 4-Aminopyridine; Amiloride; Animals; Apamin; Cells, Cultured; Dopamine; Ion Channels; Mesencephalon; Neurotensin; Nifedipine; omega-Conotoxin GVIA; Peptides; Phorbol Esters; Potassium; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Tritium | 1994 |
Characterization of K+ and Ca2+ ionic currents in glomerulosa cells from human adrenal glands.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Action Potentials; Adolescent; Adult; Aldosterone; Barium; Cadmium; Calcium Channels; Cells, Cultured; Electric Conductivity; Humans; Kinetics; Membrane Potentials; Nickel; Nifedipine; Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Zona Glomerulosa | 1994 |
[4-Aminopyridine induced histamine release and its antagonism by certain drugs].
Topics: 4-Aminopyridine; Animals; Calcium Channel Blockers; Female; Gallic Acid; Histamine; Histamine Release; Lung; Male; Mast Cells; Mice; Minoxidil; Nifedipine | 1994 |
Transient outward current in opossum esophageal circular muscle.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cadmium; Calcium Channels; Egtazic Acid; Esophagus; In Vitro Techniques; Membrane Potentials; Muscle, Smooth; Nifedipine; Opossums; Patch-Clamp Techniques; Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds | 1995 |
Antianginal effects of YM-16151-4 in various experimental angina models.
Topics: 4-Aminopyridine; Amifampridine; Angina Pectoris; Animals; Arginine Vasopressin; Atrioventricular Node; Calcium Channel Blockers; Coronary Circulation; Coronary Vasospasm; Dihydropyridines; Dogs; Electrocardiography; Female; Heart Conduction System; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitrophenols; Oxygen Consumption; Potassium Channels; Propranolol | 1993 |
Activation of a slow outward current by the calcium released during contraction of cultured rat skeletal muscle cells.
Topics: 4-Aminopyridine; Animals; Apamin; Caffeine; Calcium; Cells, Cultured; Cesium; Charybdotoxin; Egtazic Acid; Electric Conductivity; Electric Stimulation; Membrane Potentials; Muscle Contraction; Muscles; Nifedipine; Potassium; Rats; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1993 |
A simple method for measurement of ureteric peristaltic function in vivo and the effects of drugs acting on ion channels applied from the ureter lumen in anesthetized rats.
Topics: 4-Aminopyridine; Anesthesia; Animals; Benzopyrans; Cromakalim; Glyburide; Ion Channels; Lidocaine; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Pyrroles; Rats; Rats, Sprague-Dawley; Ureter; Vasodilator Agents | 1993 |
Voltage dependent fast calcium current in cultured skeletal myocytes of the frog Rana temporaria.
Topics: 4-Aminopyridine; Animals; Calcium Channels; Cells, Cultured; Embryo, Nonmammalian; Kinetics; Membrane Potentials; Muscle, Skeletal; Nifedipine; Patch-Clamp Techniques; Rana temporaria; Tetrodotoxin | 1994 |
Inhibition of K+ channel activity by 4-AP stimulates N-type Ca2+ channels in CHP-100 cells.
Topics: 4-Aminopyridine; Brain Neoplasms; Calcium; Calcium Channel Agonists; Calcium Channels; Cell Membrane; Humans; Neuroblastoma; Nifedipine; omega-Conotoxin GVIA; Peptides; Potassium Channels; Rubidium Radioisotopes; Synaptosomes; Tetrodotoxin; Tumor Cells, Cultured | 1994 |
Tetraethylammonium selectively stimulates secretion from noradrenergic bovine chromaffin cells.
Topics: 4-Aminopyridine; Animals; Calcium; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Drug Interactions; Drug Synergism; Epinephrine; Glyburide; Nifedipine; Norepinephrine; Ouabain; Phorbol 12,13-Dibutyrate; Potassium Channel Blockers; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Tolbutamide | 1994 |
Ionic currents and endothelin signaling in smooth muscle cells from rat renal resistance arteries.
Topics: 4-Aminopyridine; Animals; Arterioles; Caffeine; Calcium; Cell Membrane; Cobalt; Egtazic Acid; Electric Conductivity; Endothelins; Fluorescent Dyes; Fura-2; In Vitro Techniques; Kidney; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nifedipine; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Renal Circulation; Signal Transduction; Spectrometry, Fluorescence; Tetraethylammonium; Tetraethylammonium Compounds; Vascular Resistance | 1994 |
Multiple potassium conductances and their role in action potential repolarization and repetitive firing behavior of neonatal rat hypoglossal motoneurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Apamin; Calcium; Calcium Channel Blockers; Electrophysiology; Female; Hypoglossal Nerve; In Vitro Techniques; Male; Membrane Potentials; Motor Neurons; Nifedipine; omega-Conotoxin GVIA; Peptides; Potassium Channels; Rats; Tetraethylammonium Compounds | 1993 |
Voltage-gated ionic currents in smooth muscle cells of guinea pig proximal colon.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cadmium; Calcium Channels; Cell Membrane; Colon; Dose-Response Relationship, Drug; Guinea Pigs; Ion Channel Gating; Membrane Potentials; Muscle, Smooth; Nifedipine; Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1993 |
Comparison of ionic currents from interstitial cells and smooth muscle cells of canine colon.
Topics: 4-Aminopyridine; Amphotericin B; Animals; Colon; Dogs; Female; Ion Pumps; Ions; Male; Membrane Potentials; Muscle, Smooth; Nickel; Nifedipine | 1993 |
Dihydropyridines and verapamil inhibit voltage-dependent K+ current in isolated outer hair cells of the guinea pig.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Cochlea; Guinea Pigs; Hair Cells, Auditory, Outer; Membrane Potentials; Nifedipine; Nimodipine; Patch-Clamp Techniques; Potassium Channel Blockers; Quinine; Verapamil | 1995 |
Pharmacological analysis of voltage-dependent potassium currents in cultured skeletal myocytes of the frog Rana temporaria.
Topics: 4-Aminopyridine; Animals; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Dose-Response Relationship, Drug; Electric Conductivity; Embryo, Nonmammalian; Membrane Potentials; Muscle, Skeletal; Nifedipine; Patch-Clamp Techniques; Potassium Channels; Quinidine; Rana temporaria; Time Factors; Verapamil | 1995 |
Investigations on the mechanism of tetrahydro-9-aminoacridine-induced presynaptic inhibition in the rat amygdala.
Topics: 4-Aminopyridine; Alzheimer Disease; Amygdala; Animals; Baclofen; Dose-Response Relationship, Drug; Male; Membrane Potentials; Nifedipine; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tacrine; Time Factors | 1996 |
Inhibition of Toosendanin on the delayed rectifier potassium current in neuroblastoma x glioma NG108-15 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Delayed Rectifier Potassium Channels; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glioma; Hybrid Cells; Mice; Neuroblastoma; Neuromuscular Blocking Agents; Nifedipine; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Verapamil | 1997 |
Pharmacological modulation of electromechanical coupling in the proximal and distal regions of the guinea-pig renal pelvis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Action Potentials; Animals; Calcium Channel Blockers; Calcium-Transporting ATPases; Charybdotoxin; Electrophysiology; Enzyme Inhibitors; Guinea Pigs; Indoles; Kidney Pelvis; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium Channels; Sarcoplasmic Reticulum; Tetraethylammonium; Tetraethylammonium Compounds | 1997 |
Effect of 4-aminopyridine and 3,4-diaminopyridine on guinea-pig isolated ileum.
Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Animals; Atropine; Calcium Channel Blockers; Diazoxide; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Female; Flunarizine; Guinea Pigs; Ileum; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Parasympathetic Nervous System; Parasympatholytics; Potassium Channels; Vasodilator Agents; Verapamil | 1997 |
IA-type K+ channel blockers promote survival of cortical neurons in culture: involvement of L-type Ca2+ channels.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Astrocytes; Calcium Channel Blockers; Calcium Channels; Cell Count; Cell Survival; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Elapid Venoms; Neurons; Neuroprotective Agents; Nifedipine; Potassium Channels; Rats; Rats, Sprague-Dawley | 1997 |
Interactions between neuropeptide Y and the adenylate cyclase pathway in rat mesenteric small arteries: role of membrane potential.
Topics: 4-Aminopyridine; Acetylcholine; Adenylyl Cyclases; Animals; Charybdotoxin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dichlororibofuranosylbenzimidazole; Gadolinium; Glyburide; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Neuropeptide Y; Nifedipine; Potassium Channels; Rats; Rats, Wistar; Thionucleotides | 1997 |
Outward currents in smooth muscle cells isolated from sheep mesenteric lymphatics.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Animals; Calcium Channel Blockers; Calcium Channels; Female; In Vitro Techniques; Lymphatic System; Male; Membrane Potentials; Muscle, Smooth; Mycotoxins; Nifedipine; Patch-Clamp Techniques; Peptides; Potassium Channels; Sheep; Tetraethylammonium; Tetraethylammonium Compounds | 1997 |
Antianginal effects of YM430, a novel calcium entry-blocking and beta-adrenoceptor-blocking agent in several experimental angina models.
Topics: 4-Aminopyridine; Adrenergic beta-Antagonists; Amifampridine; Angina Pectoris; Animals; Calcium Channel Blockers; Coronary Disease; Coronary Vasospasm; Coronary Vessels; Dogs; Electrocardiography; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Ischemia; Nifedipine; Propranolol; Rats | 1997 |
The role of Na(+)-Ca2+ exchange current in electrical restitution in ferret ventricular cells.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Egtazic Acid; Electric Stimulation; Female; Ferrets; Heart Ventricles; Kinetics; Male; Myocardial Contraction; Myocardium; Nifedipine; Patch-Clamp Techniques; Potassium; Rats; Sodium; Sodium-Calcium Exchanger | 1997 |
Ca2+ and K+ currents regulate accommodation and firing frequency in guinea pig bronchial ganglion neurons.
Topics: 4-Aminopyridine; Animals; Apamin; Barium Compounds; Bronchi; Calcium Channel Blockers; Calcium Channels; Chlorides; Electrophysiology; Ganglia, Parasympathetic; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Neurons; Nifedipine; omega-Conotoxin GVIA; Peptides; Potassium Channel Blockers; Potassium Channels; Tetrodotoxin; Verapamil | 1998 |
Monovalent cation and L-type Ca2+ channels participate in calcium paradox-like phenomenon in rabbit aortic smooth muscle cells.
Topics: 4-Aminopyridine; Animals; Aorta; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cations, Monovalent; Cesium; Chelating Agents; Egtazic Acid; Glutamine; Imidazoles; Lithium; Magnesium; Membrane Potentials; Muscle, Smooth, Vascular; Nifedipine; Patch-Clamp Techniques; Penicillamine; Potassium; Rabbits; Sodium; Tetraethylammonium; Vasoconstriction | 1999 |
Intrinsic oscillations in CA3 hippocampal pyramids: physiological relevance to theta rhythm generation.
Topics: 4-Aminopyridine; Aging; Animals; Animals, Newborn; Calcium; Calcium Channels; Carbachol; Cesium; Hippocampus; In Vitro Techniques; Membrane Potentials; Nifedipine; Oscillometry; Patch-Clamp Techniques; Potassium Channels; Pyramidal Cells; Rats; Rats, Wistar; Tetraethylammonium; Tetrodotoxin; Theta Rhythm | 1998 |
Phoneutria nigriventer toxin Tx3-1 blocks A-type K+ currents controlling Ca2+ oscillation frequency in GH3 cells.
Topics: 4-Aminopyridine; Amino Acid Sequence; Base Sequence; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line; Charybdotoxin; Chelating Agents; DNA, Complementary; Egtazic Acid; Ion Channel Gating; Membrane Potentials; Molecular Sequence Data; Neuropeptides; Nifedipine; Patch-Clamp Techniques; Periodicity; Pituitary Gland; Potassium Channel Blockers; Potassium Channels; Spider Venoms | 1999 |
Pharmacological characterization of ionic currents that regulate the pacemaker rhythm in a weakly electric fish.
Topics: 4-Aminopyridine; Action Potentials; Animals; Biological Clocks; Cadmium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Conotoxins; Dose-Response Relationship, Drug; Electric Fish; Electric Organ; In Vitro Techniques; Neurons; Nickel; Nifedipine; Potassium Channel Blockers; Potassium Channels; Sodium Channel Blockers; Sodium Channels; Tetraethylammonium; Tetrodotoxin | 2000 |
Ca2+ influx mediates apoptosis induced by 4-aminopyridine, a K+ channel blocker, in HepG2 human hepatoblastoma cells.
Topics: 4-Aminopyridine; Apoptosis; Calcium; Calcium Channel Blockers; Cell Survival; Chelating Agents; DNA Fragmentation; Egtazic Acid; Flufenamic Acid; Hepatoblastoma; Humans; Liver Neoplasms; Manganese; Membrane Potentials; Nifedipine; Potassium Channel Blockers; Potassium Channels; Tumor Cells, Cultured; Verapamil | 2000 |
Low-voltage-activated calcium current does not regulate the firing behavior in paired mechanosensory neurons with different adaptation properties.
Topics: 4-Aminopyridine; Action Potentials; Adaptation, Physiological; Animals; Barium; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels, T-Type; Female; Kinetics; Male; Mechanoreceptors; Neurons, Afferent; Nickel; Nifedipine; omega-Conotoxin GVIA; Patch-Clamp Techniques; Spiders; Tetraethylammonium; Tetrodotoxin | 2000 |
Ionic currents in cardiac myocytes of squid, Alloteuthis subulata.
Topics: 4-Aminopyridine; Animals; Apamin; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Separation; Cells, Cultured; Decapodiformes; Membrane Potentials; Myocardium; Nifedipine; Patch-Clamp Techniques; Potassium; Sodium; Tetraethylammonium; Tetrodotoxin | 2000 |
Histamine H(3) receptors mediate inhibition of noradrenaline release from intestinal sympathetic nerves.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Adrenergic alpha-Antagonists; Animals; Calcium; Colforsin; Dose-Response Relationship, Drug; Ethylmaleimide; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Ileum; In Vitro Techniques; Intestinal Mucosa; Intestines; Male; Muscle, Smooth; Myenteric Plexus; Nifedipine; Norepinephrine; omega-Conotoxins; Pertussis Toxin; Phenols; Receptors, Histamine H3; Rolipram; Sympathetic Nervous System; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetrodotoxin; Virulence Factors, Bordetella; Yohimbine | 2000 |
Activation of pre- and postsynaptic protein kinase C during tetraethylammonium-induced long-term potentiation in the CA1 field of the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Calcium Channel Blockers; Calmodulin-Binding Proteins; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GAP-43 Protein; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Nerve Tissue Proteins; Neurogranin; Nifedipine; Phosphorylation; Potassium Channel Blockers; Potassium Channels; Presynaptic Terminals; Protein Kinase C; Rats; Signal Transduction; Synaptic Membranes; Synaptic Transmission; Tetraethylammonium | 2000 |
Nonlinear changes of transmembrane potential during defibrillation shocks: role of Ca(2+) current.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Calcium Channel Blockers; Cells, Cultured; Electric Countershock; Electrophysiology; Electroshock; Heart; Ion Channels; Membrane Potentials; Myocardium; Nifedipine; Potassium Channel Blockers; Rats; Rats, Wistar | 2000 |
Opposing roles of K(+) and Cl(-) channels in maintenance of opossum lower esophageal sphincter tone.
Topics: 4-Aminopyridine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Chloride Channels; Esophagogastric Junction; Glyburide; Isometric Contraction; Microelectrodes; Muscle, Smooth; Nifedipine; Niflumic Acid; Opossums; Potassium Channels | 2000 |
Sites and ionic mechanisms of hypoxic vasoconstriction in frog skin.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Animals; Arterioles; Calcium Channels, L-Type; Homeostasis; Hypoxia; Mammals; Muscle, Smooth, Vascular; Nifedipine; Nitrogen; Oxygen; Potassium Channel Blockers; Skin; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Venules; Xenopus laevis | 2001 |
The contribution of ionic currents to changes in refractoriness of human atrial myocytes associated with chronic atrial fibrillation.
Topics: 4-Aminopyridine; Action Potentials; Aged; Atrial Fibrillation; Atrial Function; Calcium Channel Blockers; Calcium Channels; Case-Control Studies; Chronic Disease; Drug Synergism; Electric Stimulation; Female; Humans; Ion Channels; Ion Transport; Male; Membrane Potentials; Middle Aged; Nifedipine; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels | 2001 |
Ionic basis of the resting membrane potential and action potential in the pharyngeal muscle of Caenorhabditis elegans.
Topics: 4-Aminopyridine; Action Potentials; Animals; Barium; Caenorhabditis elegans; Calcium; Calcium Channel Blockers; Calcium Channels; Chloride Channels; Chlorides; Electrophysiology; Membrane Potentials; Muscarinic Antagonists; Nifedipine; Pharyngeal Muscles; Potassium; Potassium Channel Blockers; Potassium Channels; Quinidine; Sodium; Sodium Channels; Verapamil; Veratridine | 2002 |
Channels involved in transient currents unmasked by removal of extracellular calcium in cardiac cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cesium; Chelating Agents; Diltiazem; Drug Resistance; Egtazic Acid; Electric Conductivity; Heart Ventricles; Isoproterenol; Kinetics; Magnesium; Membrane Potentials; Myocardium; Nifedipine; Patch-Clamp Techniques; Potassium; Receptors, Adrenergic, beta; Swine; Verapamil | 2002 |
Calcium channels involved in noradrenaline release from sympathetic neurones in rabbit carotid artery.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Carotid Artery, Common; Electric Stimulation; Female; Male; Neurons; Nifedipine; Nimodipine; Norepinephrine; omega-Conotoxin GVIA; Potassium Channel Blockers; Rabbits; Sympathetic Nervous System; Time Factors | 2003 |
The effect of mebudipine and dibudipine, two new Ca2+ channel blockers, in comparison with nifedipine on Ca2+ spikes of F1 neuronal soma membrane in Helix aspersa.
Topics: 4-Aminopyridine; Analysis of Variance; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Dose-Response Relationship, Drug; Electrophysiology; Esophagus; Helix, Snails; Membrane Potentials; Neurons; Nifedipine; Patch-Clamp Techniques | 2003 |
[High throughput screening method of potassium channel regulators].
Topics: 4-Aminopyridine; Animals; Barbiturates; Calcium Channel Blockers; Cromakalim; Isoxazoles; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; PC12 Cells; Piperidines; Potassium Channel Blockers; Potassium Channels; Pyridines; Quinidine; Rats | 2004 |
Substance P induces inward current and regulates pacemaker currents through tachykinin NK1 receptor in cultured interstitial cells of Cajal of murine small intestine.
Topics: 4-Aminopyridine; Action Potentials; Alkaloids; Animals; Benzophenanthridines; Calcium; Cations, Divalent; Cells, Cultured; Electrophysiology; Enteric Nervous System; Female; Glyburide; Intestine, Small; Ion Channels; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Nifedipine; Phenanthridines; Receptors, Neurokinin-1; Sinoatrial Node; Sodium; Substance P; Tachykinins; Tetraethylammonium; Tetrodotoxin | 2004 |
Characterization of the ion channel currents in single myocytes of the guinea pig prostate.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels; Electrophysiology; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Myocytes, Smooth Muscle; Nifedipine; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Prostate; Tetraethylammonium | 2004 |
Characterization of ionic currents in human mesenchymal stem cells from bone marrow.
Topics: 4-Aminopyridine; Bone Marrow Cells; Calcium Channels, L-Type; Cell Differentiation; Cells, Cultured; Ether-A-Go-Go Potassium Channels; Gene Expression; Humans; Ion Channels; Kv1.4 Potassium Channel; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Mesenchymal Stem Cells; NAV1.7 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Nifedipine; Patch-Clamp Techniques; Peptides; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Voltage-Gated; RNA, Messenger; Shal Potassium Channels; Sodium Channels; Tetrodotoxin | 2005 |
Postnatal maturational shift from PKCzeta and voltage-gated K+ channels to RhoA/Rho kinase in pulmonary vasoconstriction.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Aging; Amides; Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Endothelium, Vascular; In Vitro Techniques; Isoenzymes; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Protein Kinase C; Pulmonary Artery; Pyridines; rhoA GTP-Binding Protein; Signal Transduction; Swine; Thromboxane A2 | 2005 |
Involvement of Kv1.1 and Nav1.5 in proliferation of gastric epithelial cells.
Topics: 4-Aminopyridine; Animals; Barium; Cell Line; Cell Proliferation; Epithelial Cells; Gastric Mucosa; Gene Expression; Kv1.1 Potassium Channel; NAV1.5 Voltage-Gated Sodium Channel; Nifedipine; Patch-Clamp Techniques; Potassium; Potassium Channels; Rats; RNA, Small Interfering; Sodium; Sodium Channels | 2006 |
Survival of Swiss-Webster mouse cerebellar granule neurons is promoted by a combination of potassium channel blockers.
Topics: 4-Aminopyridine; Animals; Barium; Calcium Channel Blockers; Cell Survival; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Enzyme Inhibitors; Imidazoles; L-Lactate Dehydrogenase; Mice; Neurons; Nifedipine; Potassium; Potassium Channel Blockers; Ruthenium Red; Tetraethylammonium; Time Factors | 2007 |
Temporal variability of repolarization in rat ventricular myocytes paced with time-varying frequencies.
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels, L-Type; Heart Ventricles; In Vitro Techniques; Male; Models, Biological; Myocardial Contraction; Myocytes, Cardiac; Nifedipine; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar | 2007 |
Role of K(+) channels in the regulation of electrical spontaneous activity of the mouse small intestine.
Topics: 4-Aminopyridine; Animals; Apamin; Charybdotoxin; Electrophysiology; Female; Ileum; Male; Mice; Mice, Inbred BALB C; Nifedipine; Peptides; Phenylephrine; Potassium Channels; Potassium Channels, Calcium-Activated; Tetrodotoxin | 2007 |
Involvement of voltage-gated K+ and Na+ channels in gastric epithelial cell migration.
Topics: 4-Aminopyridine; Animals; Barium; Cell Line; Cell Movement; Epidermal Growth Factor; Epithelial Cells; Gastric Mucosa; Gene Expression Regulation; Ion Channel Gating; Nifedipine; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Rats; RNA, Messenger; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin | 2008 |
Drug assessment based on detection of L-glutamate released from C6 glioma cells using an enzyme-luminescence method.
Topics: 4-Aminopyridine; Animals; Brain Neoplasms; Carbamazepine; Cell Line, Tumor; Enzymes; Flunarizine; Glioma; Glutamic Acid; Lidocaine; Luminescence; Nickel; Nifedipine; Rats; Veratridine | 2008 |
K+ channel inhibition modulates the biochemical and morphological differentiation of human placental cytotrophoblast cells in vitro.
Topics: 4-Aminopyridine; Arachidonic Acids; Barium Compounds; Calcium Channel Blockers; Cell Differentiation; Cells, Cultured; Chlorides; Chorionic Gonadotropin; Cromakalim; Endocannabinoids; Female; Giant Cells; Humans; L-Lactate Dehydrogenase; Nifedipine; Pinacidil; Placenta; Polyunsaturated Alkamides; Potassium Channel Blockers; Potassium Channels; Pregnancy; Tetraethylammonium; Trophoblasts | 2008 |
Vasorelaxant effect of a self-etch adhesive system through calcium antagonistic action.
Topics: 4-Aminopyridine; Animals; Aorta, Thoracic; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Dentin-Bonding Agents; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Glyburide; Indomethacin; Male; Materials Testing; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Potassium Channels, Voltage-Gated; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Time Factors; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
Drug-induced changes in action potential duration are proportional to action potential duration in rat ventricular myocardium.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium Channel Blockers; Dogs; Electrophysiological Phenomena; Female; Guinea Pigs; Heart; Humans; In Vitro Techniques; Male; Models, Cardiovascular; Nifedipine; Potassium Channel Blockers; Rabbits; Rats; Rats, Wistar; Species Specificity; Tetraethylammonium | 2010 |
Characterization of ionic currents and electrophysiological properties of goldfish somatotropes in primary culture.
Topics: 4-Aminopyridine; Action Potentials; Animals; Barium; Calcium Channels; Cells, Cultured; Goldfish; Membrane Potentials; Nifedipine; omega-Conotoxin GVIA; Patch-Clamp Techniques; Potassium Channels; Sodium Channels; Somatotrophs; Tetraethylammonium Compounds | 2010 |
Mechanism of inhibition of acetylcholine secretion in newly formed mouse synapses involving Ca2+-dependent kinases and voltage-gated K+-channels.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Acetylcholine; Animals; Benzophenanthridines; Calcium Channels, L-Type; Calcium-Calmodulin-Dependent Protein Kinases; Excitatory Postsynaptic Potentials; Imidazoles; Indoles; Maleimides; Mice; Muscle, Skeletal; Nifedipine; Potassium Channels, Voltage-Gated; Protein Kinase C; Synapses | 2010 |
Pharmacological evidence that Ca²+ channels and, to a lesser extent, K+ channels mediate the relaxation of testosterone in the canine basilar artery.
Topics: 4-Aminopyridine; Adenine; Aminoglutethimide; Androgen Receptor Antagonists; Animals; Aromatase Inhibitors; Barium Compounds; Basilar Artery; Calcium Channel Blockers; Calcium Channels; Chlorides; Cycloheximide; Dactinomycin; Dogs; Enzyme Inhibitors; Flutamide; In Vitro Techniques; Male; Nifedipine; Nucleic Acid Synthesis Inhibitors; Oxadiazoles; Potassium Channel Blockers; Potassium Channels; Protein Synthesis Inhibitors; Quinoxalines; Testosterone; Vasodilation; Vasodilator Agents | 2011 |
Vasodilatory effect of hydroxyethyl methacrylate and triethylene glycol dimethacrylate in rat aorta through calcium antagonistic action.
Topics: 4-Aminopyridine; Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Calcium Chloride; Composite Resins; Cyclooxygenase Inhibitors; Dental Materials; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Indomethacin; Male; Methacrylates; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide Synthase; Polyethylene Glycols; Polymethacrylic Acids; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Transducers; Vasoconstrictor Agents; Vasodilator Agents | 2011 |
Role of calcium and potassium channels in effects of hydrogen sulfide on frog myocardial contractility.
Topics: 4-Aminopyridine; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Electric Stimulation; Glyburide; Heart; Hydrogen Sulfide; In Vitro Techniques; KATP Channels; Minoxidil; Myocardial Contraction; Myocardium; Nifedipine; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Rana ridibunda; Tetraethylammonium | 2011 |
Cardiac tissue slices with prolonged survival for in vitro drug safety screening.
Topics: 4-Aminopyridine; Action Potentials; Animal Testing Alternatives; Animals; Animals, Laboratory; Anti-Arrhythmia Agents; Calcium Channel Blockers; Carbenoxolone; Disease Models, Animal; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Male; Nifedipine; Piperidines; Potassium Channel Blockers; Pyridines; Rats; Rats, Wistar; Risk Assessment; Toxicity Tests | 2012 |
Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons.
Topics: 4-Aminopyridine; Analysis of Variance; Animals; Bicuculline; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Corpus Striatum; CREB-Binding Protein; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agents; Female; GABA-A Receptor Antagonists; Glutamate Decarboxylase; Glycine Agents; Luminescent Proteins; Microfluidic Analytical Techniques; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nifedipine; Patch-Clamp Techniques; Potassium Channel Blockers; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sodium Channel Blockers; Strychnine; Synapses; Tetrodotoxin; Transfection; Vesicular Glutamate Transport Protein 1 | 2012 |
Gastric emptying and Ca(2+) and K(+) channels of circular smooth muscle cells in diet-induced obese prone and resistant rats.
Topics: 4-Aminopyridine; Animals; Calcium Channels; Diet; Diet, High-Fat; Gastric Emptying; Male; Myocytes, Smooth Muscle; Nifedipine; Obesity; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Weight Gain | 2013 |
Serotonin contracts the rat mesenteric artery by inhibiting 4-aminopyridine-sensitive Kv channels via the 5-HT2A receptor and Src tyrosine kinase.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Ketanserin; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nifedipine; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Spiperone; src-Family Kinases; Vasoconstriction | 2013 |
I
Topics: 4-Aminopyridine; Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Electrophysiological Phenomena; Heart Atria; Kinetics; Myocytes, Cardiac; Nifedipine; Potassium Channel Blockers; Pyridines; Rabbits; Single-Cell Analysis; Sodium Channel Blockers; Sodium Channels; Triazoles | 2018 |