nifedipine and 1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester

nifedipine has been researched along with 1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andersen, N; Gougoutas, J; Hedberg, A; Kimball, SD; Malley, M; Moreland, S; Porubcan, M; Pudzianowski, A; Rovnyak, G1
Coburn, RA; Solo, AJ; Suto, MJ; Triggle, AM; Triggle, DJ; Wierzba, M1
Dagnino, L; Knaus, EE; Li-Kwong-Ken, MC; Triggle, CR; Wolowyk, MW; Wynn, H1
Fossheim, R; Mostad, A; Rømming, C; Shefter, E; Svarteng, K; Triggle, DJ1
Cao, S; Chang, CC; Dunne, SF; Kai, L; Kang, S; Luan, CH; Pandey, P; Silverman, RB; Surmeier, DJ; Tian, X1
Caron, G; Ermondi, G; Galietta, L; Medana, C; Pedemonte, N; Visentin, S1

Other Studies

6 other study(ies) available for nifedipine and 1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester

ArticleYear
Studies directed toward ascertaining the active conformation of 1,4-dihydropyridine calcium entry blockers.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:5

    Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Guinea Pigs; In Vitro Techniques; Models, Molecular; Molecular Conformation; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Rabbits; Radioligand Assay; Receptors, Nicotinic; Structure-Activity Relationship

1988
1,4-Dihydropyridine antagonist activities at the calcium channel: a quantitative structure-activity relationship approach.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:11

    Topics: Animals; Calcium Channels; Dihydropyridines; Guinea Pigs; In Vitro Techniques; Mathematics; Muscle Contraction; Structure-Activity Relationship

1988
Synthesis and calcium channel antagonist activity of dialkyl 4- (dihydropyridinyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylates.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:4

    Topics: Animals; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dicarboxylic Acids; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Pyridines; Receptors, Muscarinic; Structure-Activity Relationship

1987
Crystal structures and pharmacological activity of calcium channel antagonists: 2,6-dimethyl-3,5-dicarbomethoxy-4-(unsubstituted, 2-methyl-, 4-methyl-, 3-nitro-, 4-nitro-, and 2,4-dinitrophenyl)-1,4-dihydropyridine.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:2

    Topics: Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dihydropyridines; Models, Molecular; Molecular Conformation; Nifedipine; Phosphorylcholine; Pyridines; Structure-Activity Relationship; X-Ray Diffraction

1982
Antagonism of 4-substituted 1,4-dihydropyridine-3,5-dicarboxylates toward voltage-dependent L-type Ca2+ channels Ca V 1.3 and Ca V 1.2.
    Bioorganic & medicinal chemistry, 2010, May-01, Volume: 18, Issue:9

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Dicarboxylic Acids; Dihydropyridines; Humans; Inhibitory Concentration 50; Molecular Structure; Nifedipine

2010
Ligand-based design, in silico ADME-Tox filtering, synthesis and biological evaluation to discover new soluble 1,4-DHP-based CFTR activators.
    European journal of medicinal chemistry, 2012, Volume: 55

    Topics: Absorption; Animals; Calcium Channel Blockers; Chemistry Techniques, Synthetic; Computational Biology; Cystic Fibrosis Transmembrane Conductance Regulator; Dihydropyridines; Drug Design; Humans; Ligands; Models, Molecular; Mutation; Protein Conformation; Quantitative Structure-Activity Relationship; Rats; Solubility

2012