nicotine has been researched along with wortmannin in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Akaike, A; Honda, K; Kihara, T; Kume, T; Nakamizo, T; Sawada, H; Shibasaki, H; Shimohama, S | 1 |
| Fu, WM; Huang, WP; Hung, SY; Liou, HC | 1 |
| Chung, HT; Jeong, GS; Kim, EC; Kim, YS; Lee, SK; Oh, HW; Pae, HO; Pi, SH | 1 |
| Arrazola, MS; Carvajal, FJ; Farias, GG; Godoy, JA; Inestrosa, NC; Rios, JA; Serrano, FG; Vargas, JY | 1 |
7 other study(ies) available for nicotine and wortmannin
| Article | Year |
|---|---|
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Androstadienes; Animals; Blotting, Western; Bungarotoxins; Calcineurin; Cell Death; Cells, Cultured; Cerebral Cortex; Chromones; Enzyme Inhibitors; Glutamic Acid; Immunoblotting; Models, Biological; Morpholines; Neurons; Nicotine; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-fyn; Rats; Receptors, Nicotinic; Signal Transduction; Wortmannin | 2001 |
Autophagy protects neuron from Abeta-induced cytotoxicity.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Androstadienes; Animals; Autophagy; Autophagy-Related Protein 7; Cell Line, Tumor; Cells, Cultured; Cytoprotection; Gene Knockdown Techniques; Green Fluorescent Proteins; Hippocampus; Humans; Macrolides; Microtubule-Associated Proteins; Neurons; Nicotine; Phagosomes; Rats; Rats, Wistar; Receptors, Nicotinic; Ubiquitin-Activating Enzymes; Wortmannin | 2009 |
Heme oxygenase-1 mediates nicotine- and lipopolysaccharide-induced expression of cyclooxygenase-2 and inducible nitric oxide synthase in human periodontal ligament cells.
Topics: Androstadienes; Anthracenes; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Enzyme Inhibitors; Heme Oxygenase-1; Humans; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Metalloporphyrins; NF-kappa B; Nicotine; Nitric Oxide; Nitric Oxide Synthase Type II; Periodontal Ligament; Phosphoinositide-3 Kinase Inhibitors; Protoporphyrins; RNA, Small Interfering; Transfection; Wortmannin | 2010 |
Nicotine prevents synaptic impairment induced by amyloid-β oligomers through α7-nicotinic acetylcholine receptor activation.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Androstadienes; Animals; beta Catenin; Bungarotoxins; Cells, Cultured; Dendrites; Disks Large Homolog 4 Protein; Hippocampus; Intracellular Signaling Peptides and Proteins; Maze Learning; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurites; Neurons; Nicotine; Patch-Clamp Techniques; Peptide Fragments; Phosphatidylinositol 3-Kinases; Plaque, Amyloid; Presenilin-1; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Signal Transduction; Synapsins; Wnt Proteins; Wnt Signaling Pathway; Wortmannin | 2013 |