nicotine has been researched along with warfarin in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (14.89) | 18.7374 |
| 1990's | 1 (2.13) | 18.2507 |
| 2000's | 21 (44.68) | 29.6817 |
| 2010's | 17 (36.17) | 24.3611 |
| 2020's | 1 (2.13) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Caron, G; Ermondi, G | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Carrupt, PA; Martel, S; Ottaviani, G | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Majewski, F | 1 |
| Vorherr, H | 1 |
| Cooper, SD; De la Iglesia, FA; Feuer, G; Lumb, G; Miller, DR | 1 |
| Kasperbauer, MJ; Sorokin, TP; Tso, TC | 1 |
| Elmenhorst, H; Goertz, E; Stadler, L | 1 |
| Levy, G | 1 |
| Inoue, K; Shimada, T; Yamazaki, H | 1 |
| Cloak, CC; Lin, KM; Nuccio, I; Pechnick, RN; Poland, RE; Wan, YJ | 1 |
| Aygün Kocabaş, N; Cholerton, S; Cok, I; Karakaya, AE; Sardaş, S | 1 |
| Berthou, F; Dréano, Y; Le Gal, A; Lucas, D | 1 |
| Cashman, JR; Fandrick, K; MacDougall, JM; Serafin, SV; Zhang, X | 1 |
| DEWEY, LJ; STEPKA, W | 1 |
| Fujieda, M; Kamataki, T; Kiyotani, K; Peamkrasatam, S; Sriwatanakul, K; Yamazaki, H; Yoovathaworn, K | 1 |
| Higashi, E; Katoh, M; Nakajima, M; Tokudome, S; Yokoi, T | 1 |
| Brown, SA | 1 |
| Ashton, M; Asimus, S; Hai, TN; Van Huong, N | 1 |
| Anzenbacher, P; Otyepka, M; Skopalík, J | 1 |
| Bultinck, P; Van Damme, S | 1 |
| Choi, S; Chun, YJ; Chung, MW; Han, S; Kim, D; Lee, CH; Na, HS; Shin, HJ; Yun, CH | 1 |
| Rahnasto-Rilla, M; Raunio, H | 1 |
| Murphy, SE; Retzlaff, C; von Weymarn, LB | 1 |
| Cappendijk, SL; Miksys, S; Perry, WM; Tyndale, RF; Zhao, B | 1 |
| van Dam, NM | 1 |
| Chiba, M; Ishii, Y; Yamada, H; Yamamiya, I; Yoshisue, K | 1 |
| Chun, YJ; Han, S; Kim, D; Kim, JH; Lee, H; Lim, YR; Park, HG; Park, SW | 1 |
| Endo, D; Inoue, H; Kirisawa, R; Kitazawa, T; Komatsu, T; Kubota, A; Okamatsu, G; Onaga, T; Teraoka, H; Uchide, T; Uno, Y; Yin, G | 1 |
| Capelo, JL; Cavaleiro, JA; Faustino, MA; Lodeiro, C; Menezes, JC; Neves, Mda G; Oliveira, E; Santos, CI; Santos, HM | 1 |
| Biala, G; Budzynska, B; Kruk-Slomka, M; Skalicka-Wozniak, K; Wydrzynska-Kuzma, M | 1 |
| Hirasawa, N; Hiratsuka, M; Hosono, H; Kumondai, M; Maekawa, M; Mano, N; Oda, A; Yamaguchi, H | 2 |
| Chaurasia, DK; Katara, P; Kesharwani, A; Yadav, A | 1 |
4 review(s) available for nicotine and warfarin
| Article | Year |
|---|---|
[On certain embryopathies induced by teratogenic agents (author's transl].
Topics: Abnormalities, Drug-Induced; Aminopterin; Busulfan; Chlorambucil; Cyclophosphamide; Ethanol; Germany, West; Heroin Dependence; Humans; Infant Mortality; Infant, Newborn; Lysergic Acid Diethylamide; Mercaptopurine; Nicotine; Phenytoin; Radiation Injuries; Teratogens; Thalidomide; Trimethadione; Warfarin | 1977 |
Drug excretion in breast milk.
Topics: Anti-Bacterial Agents; Barbiturates; Biological Transport, Active; Breast; Breast Feeding; Caffeine; Chloramphenicol; Contraceptives, Oral; Coumarins; Female; Fluorine; Humans; Hydrogen-Ion Concentration; Infant; Infant, Newborn; Infant, Premature, Diseases; Jaundice, Neonatal; Lactation; Meprobamate; Milk, Human; Models, Biological; Morphine; Nicotine; Pesticides; Pharmaceutical Preparations; Phenytoin; Potassium Iodide; Pregnancy; Salicylates; Sulfonamides; Time Factors | 1974 |
Pharmacologic target-mediated drug disposition.
Topics: Animals; Biotransformation; Models, Biological; Nicotine; Pharmacokinetics; Tissue Distribution; Warfarin | 1994 |
CYP2A6: genetics, structure, regulation, and function.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP2A6; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Mice; Models, Molecular; Multigene Family; Neoplasms; Nicotine; Nicotinic Agonists; Polymorphism, Genetic; Smoking; Substrate Specificity | 2012 |
2 trial(s) available for nicotine and warfarin
| Article | Year |
|---|---|
In vivo evaluation of coumarin and nicotine as probe drugs to predict the metabolic capacity of CYP2A6 due to genetic polymorphism in Thais.
Topics: Administration, Oral; Adolescent; Adult; Anticoagulants; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; Drug Combinations; Female; Gene Frequency; Genotype; Humans; Hydroxyethylrutoside; Male; Middle Aged; Mixed Function Oxygenases; Nicotine; Nicotinic Agonists; Phenotype; Polymethacrylic Acids; Polymorphism, Genetic; Polyvinyls; Thailand; Tobacco Use Cessation Devices; Umbelliferones | 2006 |
Artemisinin and CYP2A6 activity in healthy subjects.
Topics: Adult; Antimalarials; Area Under Curve; Artemisinins; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Coumarins; Cross-Over Studies; Cytochrome P-450 CYP2A6; Enzyme Induction; Humans; Male; Mixed Function Oxygenases; Nicotine; Tandem Mass Spectrometry; Umbelliferones; Vietnam | 2008 |
41 other study(ies) available for nicotine and warfarin
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
The influence of methyl groups on toxicity and drug metabolism.
Topics: Administration, Oral; Amphetamine; Animals; Carbon Isotopes; Coumarins; Enzyme Induction; Female; Humans; Mephobarbital; Methylation; Microscopy, Electron; Microsomes, Liver; Nicotine; Phenobarbital; Phenols; Phospholipids; Pyrazoles; Rats; Structure-Activity Relationship; Tritium | 1973 |
Effect of photoperiod and end-of-day light quality on alkaloids and phenolic compounds of tobacco.
Topics: Alkaloids; Chlorogenic Acid; Coumarins; Cyclohexanecarboxylic Acids; Light; Nicotiana; Nicotine; Periodicity; Plants, Toxic; Quinic Acid; Rutin; Tropanes | 1970 |
[Fractionation of cigarette smoke condensate. II. Gel filtration chromatography of the fluorescing components of a water-soluble fraction of cigarette smoke condensate].
Topics: Alkaloids; Chemistry Techniques, Analytical; Chromatography, Gel; Coumarins; Cyclic N-Oxides; Fluorescence; Indoles; Nicotiana; Nicotine; Nicotinic Acids; Plants, Toxic; Smoking; Water | 1969 |
CYP2A6 genetic polymorphisms and liver microsomal coumarin and nicotine oxidation activities in Japanese and Caucasians.
Topics: Aryl Hydrocarbon Hydroxylases; Asian People; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; DNA; DNA Primers; Gene Deletion; Genotype; Humans; Japan; Microsomes, Liver; Mixed Function Oxygenases; Mutation; Nicotine; Oxidation-Reduction; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; White People | 2000 |
Effect of cigarette smoking on coumarin metabolism in humans.
Topics: Administration, Oral; Adolescent; Adult; Anticoagulants; Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Female; Ganglionic Stimulants; Humans; Male; Middle Aged; Mixed Function Oxygenases; Nicotine; Smoking | 2000 |
Determination of coumarin metabolism in Turkish population.
Topics: Adult; Aged; Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Female; Gene Frequency; Genotype; Humans; Isoenzymes; Male; Middle Aged; Mixed Function Oxygenases; Nicotine; Phenotype; Point Mutation; Polymorphism, Genetic; Smoking; Turkey; Umbelliferones | 2001 |
Diversity of selective environmental substrates for human cytochrome P450 2A6: alkoxyethers, nicotine, coumarin, N-nitrosodiethylamine, and N-nitrosobenzylmethylamine.
Topics: Adult; Antibodies, Blocking; Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Coumarins; Cytochrome P-450 CYP2A6; Diethylnitrosamine; Dimethylnitrosamine; Environmental Pollutants; Enzyme Inhibitors; Ethers; Female; Humans; In Vitro Techniques; Male; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Nicotine; Substrate Specificity | 2003 |
Inhibition of human liver microsomal (S)-nicotine oxidation by (-)-menthol and analogues.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Haplorhini; Humans; In Vitro Techniques; Menthol; Microsomes, Liver; Mixed Function Oxygenases; Nicotine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Smoking; Stereoisomerism; Steroid Hydroxylases | 2003 |
Scopolin: its isolation, characterization and relation to nicotine metabolism in harvested tobacco.
Topics: Biochemical Phenomena; Coumarins; Glucosides; Humans; Nicotiana; Nicotine | 1963 |
Inhibitory effects of neurotransmitters and steroids on human CYP2A6.
Topics: Aldehyde Oxidase; Androgens; Animals; Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Cell Line; Corticosterone; Coumarins; Cytochrome P-450 CYP2A6; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epinephrine; Estrogens; Histamine; Hormones; Humans; Hydroxylation; In Vitro Techniques; Insecta; Liver; Microsomes, Liver; Mixed Function Oxygenases; Molecular Structure; Neurotransmitter Agents; Nicotine; Norepinephrine; Phenotype; Recombinant Proteins; Serotonin; Tryptamines | 2007 |
Dr. Stewart A. Brown (PSNA phytochemistry pioneer).
Topics: Awards and Prizes; Biochemistry; Canada; Coumarins; History, 20th Century; Lignin; Methylation; Nicotine; Plants; Societies, Scientific | 2007 |
Flexibility of human cytochromes P450: molecular dynamics reveals differences between CYPs 3A4, 2C9, and 2A6, which correlate with their substrate preferences.
Topics: Aryl Hydrocarbon Hydroxylases; Binding Sites; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Liver; Models, Molecular; Nicotiana; Nicotine; Pharmaceutical Preparations; Protein Conformation; Steroids; Substrate Specificity; Temperature | 2008 |
Conceptual DFT properties-based 3D QSAR: analysis of inhibitors of the nicotine metabolizing CYP2A6 enzyme.
Topics: Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP2A6; Enzyme Inhibitors; Humans; Imidazoles; Models, Chemical; Models, Molecular; Nicotine; Protein Binding; Quantitative Structure-Activity Relationship; Quantum Theory | 2009 |
Functional characterization of allelic variants of polymorphic human cytochrome P450 2A6 (CYP2A6*5, *7, *8, *18, *19, and *35).
Topics: Alleles; Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP2A6; Humans; Hydroxylation; Imidazoles; NADP; Nicotine; Oxidation-Reduction; Polymorphism, Single Nucleotide; Recombinant Proteins | 2012 |
CYP2A6- and CYP2A13-catalyzed metabolism of the nicotine Δ5'(1')iminium ion.
Topics: Aryl Hydrocarbon Hydroxylases; Catalysis; Chromatography, High Pressure Liquid; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; Enzyme Inhibitors; Humans; Kinetics; NADP; Nicotiana; Nicotine; Nicotinic Agonists; Oxidation-Reduction; Tritium | 2012 |
Nicotine kinetics in zebra finches in vivo and in vitro.
Topics: Animals; Brain; Coumarins; Finches; Humans; Male; Microsomes, Liver; Nicotine | 2013 |
Plant chemical ecology finally gets to its root(s).
Topics: Alkaloids; Coumarins; Cyclopentanes; Ecology; Nicotine; Oxylipins; Pheromones; Plant Roots; Plants; Signal Transduction | 2014 |
Effect of CYP2A6 genetic polymorphism on the metabolic conversion of tegafur to 5-fluorouracil and its enantioselectivity.
Topics: Cell Line; Coumarins; Cytochrome P-450 CYP2A6; DNA, Complementary; Escherichia coli; Fluorouracil; Humans; Microsomes, Liver; Nicotine; Polymorphism, Genetic; Sf9 Cells; Tegafur | 2014 |
Directed-evolution analysis of human cytochrome P450 2A6 for enhanced enzymatic catalysis.
Topics: Catalysis; Catalytic Domain; Coumarins; Cytochrome P-450 CYP2A6; Directed Molecular Evolution; Humans; Hydroxylation; Imidazoles; Liver; Mutagenesis; Mutation; Nicotine; Nitrosamines; Oxidation-Reduction; Protein Conformation; Protein Engineering; Recombinant Proteins | 2014 |
Identification and functional characterization of novel feline cytochrome P450 2A.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cats; Cattle; Coumarins; Dogs; Gene Expression Regulation, Enzymologic; Humans; Liver; Nicotine; Organ Specificity; Swine | 2015 |
Untangling interactions of a zinc(II) complex containing a coumarin-porphyrin unit with alkaloids in water solutions: a photophysical study.
Topics: Caffeine; Cotinine; Coumarins; Ethanol; Fresh Water; Molecular Structure; Nicotine; Photochemical Processes; Porphyrins; Portugal; Solutions; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrum Analysis; Ultraviolet Rays; Zinc | 2015 |
In vivo modulation of the behavioral effects of nicotine by the coumarins xanthotoxin, bergapten, and umbelliferone.
Topics: 5-Methoxypsoralen; Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Coumarins; Cytochrome P-450 CYP2A6; Depression; Locomotion; Male; Memory; Methoxsalen; Mice; Nicotine; Nicotinic Agonists; Nootropic Agents; Swimming; Umbelliferones | 2016 |
Functional Characterization of 34 CYP2A6 Allelic Variants by Assessment of Nicotine C-Oxidation and Coumarin 7-Hydroxylation Activities.
Topics: Alleles; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; HEK293 Cells; Humans; Hydroxylation; Kinetics; Microsomes; Models, Molecular; Nicotine; Oxidation-Reduction; Polymorphism, Genetic; Substrate Specificity; Transfection; Umbelliferones | 2017 |
Functional characterization of 9 CYP2A13 allelic variants by assessment of nicotine C-oxidation and coumarin 7-hydroxylation.
Topics: Alleles; Aryl Hydrocarbon Hydroxylases; Coumarins; Genetic Variation; HEK293 Cells; Humans; Hydroxylation; Imidazoles; Nicotine; Oxidation-Reduction; Protein Structure, Secondary | 2018 |
Mining of molecular insights of CYP2A6 and its variants complex with coumarin (CYP2A6*-coumarin) using molecular dynamics simulation.
Topics: Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP2A6; Mixed Function Oxygenases; Molecular Dynamics Simulation; Nicotine | 2023 |