Page last updated: 2024-08-26

nicotine and tryptophan

nicotine has been researched along with tryptophan in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199012 (30.77)18.7374
1990's6 (15.38)18.2507
2000's9 (23.08)29.6817
2010's9 (23.08)24.3611
2020's3 (7.69)2.80

Authors

AuthorsStudies
Bellman, K; Knegtel, RM; Settimo, L1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bertrand, D; Bertrand, S; Changeux, JP; Devillers-Thiéry, A; Galzi, JL; Revah, F1
Bowen, DJ; Fox, E; Spring, B1
Chai, CY; Lee, EH; Tang, YP; Tsai, MJ1
Banfi, L; Kozak, W; Valzelli, L1
Oswald, I1
Leete, E1
Bonollo, L; Chiancone, FM1
Abdel-Tawab, GA; el-Shafei, AK; el-Zoghby, SM; Kelada, FS1
Balfour, DJ; Benwell, ME1
Badawy, AA; Evans, M; Punjani, NF2
Ihara, H; Knöfler, R; Takada, A; Takada, Y; Urano, T1
Ihara, H; Takada, A; Takada, Y; Urano, T2
Chiara, DC; Cohen, JB; Middleton, RE1
Basurco, J; De Luca, V; Guillet, G; Poupart, J1
Arun, P; Deepadevi, KV; Kurup, PA; Manojkumar, V; Ravikumar, A1
Arun, P; Devi, KV; Kurup, PA; Ravikumar, A1
Gaynor, CM; Handley, SL1
Beene, DL; Brandt, GS; Dougherty, DA; Lester, HA; Zacharias, NM; Zhong, W1
DE CLERCQM, M; TRUHAUT, R2
TENCONI, LT1
Kurup, PA; Kurup, RK1
Cashin, AL; Dougherty, DA; Lester, HA; Petersson, EJ1
Dougherty, DA; Lester, HA; Puskar, NL; Shanata, JA; Xiu, X1
Arseneault, L; Benkelfat, C; Booij, L; Diksic, M; Gravel, P; Lévesque, ML; Leyton, M; Tremblay, RE; Vitaro, F1
Ilivitsky, V; Knott, V; Shah, D; Thompson, A1
Anderson, G; Maes, M1
Bisserbe, JC; Blais, C; Bowers, H; Ilivitsky, V; Knott, V; Shah, D; Thompson, A1
Brunetti, IL; Khalil, NM; Oliveira, OM1
Dougherty, DA; Lester, HA; Post, MR1
Bano, S; Sajid, F1
Fujii, M; Hirata, K; Ishiuchi, SI; Santis, GD; Takeda, N; Tsuruta, K; Xantheas, SS1
Chan, KC; Cheng, X; Li, Z; Nickels, JD1
Badawy, AA; Bano, S; Hamid, SB; Sajid, F; Sharif, H1

Reviews

3 review(s) available for nicotine and tryptophan

ArticleYear
Drugs and sleep.
    Pharmacological reviews, 1968, Volume: 20, Issue:4

    Topics: Aminobutyrates; Amphetamine; Animals; Antidepressive Agents; Barbiturates; Caffeine; Cats; Clinical Trials as Topic; Dihydroxyphenylalanine; Dreams; Drug Utilization; Ethanol; Hormones; Humans; Hydroxybutyrates; Hypnotics and Sedatives; Lysergic Acid Diethylamide; Methods; Monoamine Oxidase Inhibitors; Morphine; Nicotine; Parasympatholytics; Parasympathomimetics; Phenytoin; Rats; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tryptophan

1968
Alkaloid biosynthesis.
    Advances in enzymology and related areas of molecular biology, 1969, Volume: 32

    Topics: Alkaloids; Animals; Carboxy-Lyases; Indoles; Lyases; Methylation; Mixed Function Oxygenases; Monoamine Oxidase; Nicotine; Nicotinic Acids; Plants; Pyrrolidines; Terpenes; Transaminases; Transferases; Tryptophan

1969
TRYCAT pathways link peripheral inflammation, nicotine, somatization and depression in the etiology and course of Parkinson's disease.
    CNS & neurological disorders drug targets, 2014, Volume: 13, Issue:1

    Topics: Animals; Depression; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Nicotine; Parkinson Disease; Signal Transduction; Somatoform Disorders; Tryptophan

2014

Trials

3 trial(s) available for nicotine and tryptophan

ArticleYear
Tryptophan and high-carbohydrate diets as adjuncts to smoking cessation therapy.
    Journal of behavioral medicine, 1991, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Anxiety; Behavior Therapy; Combined Modality Therapy; Diet; Dietary Carbohydrates; Humans; Middle Aged; Nicotine; Placebos; Smoking; Smoking Prevention; Substance Withdrawal Syndrome; Tryptophan; Weight Gain

1991
Drugs and sleep.
    Pharmacological reviews, 1968, Volume: 20, Issue:4

    Topics: Aminobutyrates; Amphetamine; Animals; Antidepressive Agents; Barbiturates; Caffeine; Cats; Clinical Trials as Topic; Dihydroxyphenylalanine; Dreams; Drug Utilization; Ethanol; Hormones; Humans; Hydroxybutyrates; Hypnotics and Sedatives; Lysergic Acid Diethylamide; Methods; Monoamine Oxidase Inhibitors; Morphine; Nicotine; Parasympatholytics; Parasympathomimetics; Phenytoin; Rats; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tryptophan

1968
Neural expression of nicotine's antidepressant properties during tryptophan depletion: an EEG study in healthy volunteers at risk for depression.
    Biological psychology, 2012, Volume: 91, Issue:2

    Topics: Administration, Cutaneous; Affect; Alpha Rhythm; Antidepressive Agents; Brain Mapping; Cerebral Cortex; Depression; Double-Blind Method; Electroencephalography; Female; Humans; Male; Nicotine; Nicotinic Agonists; Tryptophan

2012

Other Studies

34 other study(ies) available for nicotine and tryptophan

ArticleYear
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Functional significance of aromatic amino acids from three peptide loops of the alpha 7 neuronal nicotinic receptor site investigated by site-directed mutagenesis.
    FEBS letters, 1991, Dec-09, Volume: 294, Issue:3

    Topics: Acetylcholine; Amino Acid Sequence; Animals; Bungarotoxins; Chickens; Dihydro-beta-Erythroidine; Electrophysiology; Female; Ion Channel Gating; Molecular Sequence Data; Mutagenesis, Site-Directed; Neurons; Nicotine; Oocytes; Receptors, Nicotinic; Torpedo; Transfection; Tryptophan; Tyrosine; Xenopus

1991
Differential biochemical mechanisms mediate locomotor stimulation effects by caffeine and nicotine in rats.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 26, Issue:2

    Topics: Animals; Brain; Caffeine; Cyclic AMP; Dopamine; Kinetics; Male; Motor Activity; Nicotine; Norepinephrine; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine

1987
Exploratory behavior and the dual activity of some psychoactive drugs: Part II.
    Methods and findings in experimental and clinical pharmacology, 1987, Volume: 9, Issue:12

    Topics: Animals; Exploratory Behavior; Male; Mice; Nicotine; Phenylalanine; Piracetam; Psychotropic Drugs; Pyrrolidines; Tryptophan; Tyrosine; Yohimbine

1987
[Tobacco smoking, nicotine and tryptophan metabolism].
    Acta vitaminologica et enzymologica, 1969, Volume: 23, Issue:3

    Topics: Humans; Indoleacetic Acids; Nicotine; Smoking; Tryptamines; Tryptophan

1969
Studies on the effect of reserpine therapy on the functional capacity of the tryptophan-niacin pathway in smoker and non-smoker males.
    Biochemical pharmacology, 1970, Volume: 19, Issue:5

    Topics: Adult; Aminohippuric Acids; Carboxy-Lyases; Catecholamines; Glucuronates; Humans; Isonicotinic Acids; Kynurenic Acid; Kynurenine; Male; Nicotine; Nicotinic Acids; ortho-Aminobenzoates; Pyridines; Pyridoxal Phosphate; Pyridoxine; Reserpine; Smoking; Tryptophan; Xanthurenates

1970
The effects of nicotine administration on 5-HT uptake and biosynthesis in rat brain.
    European journal of pharmacology, 1982, Oct-15, Volume: 84, Issue:1-2

    Topics: Animals; Brain; Hippocampus; In Vitro Techniques; Indoles; Male; Nerve Tissue Proteins; Nicotine; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes; Tryptophan

1982
The role of liver tryptophan pyrrolase in the opposite effects of chronic administration and subsequent withdrawal of drugs of dependence on rat brain tryptophan metabolism.
    The Biochemical journal, 1981, Apr-15, Volume: 196, Issue:1

    Topics: Animals; Brain; Humans; Liver; Male; Methylphenazonium Methosulfate; Morphine; Naloxone; Nicotine; Phenobarbital; Rats; Substance Withdrawal Syndrome; Tryptophan; Tryptophan Oxygenase

1981
Reversal by naloxone of the effects of chronic administration of drugs of dependence on rat liver and brain tryptophan metabolism.
    British journal of pharmacology, 1981, Volume: 74, Issue:2

    Topics: Animals; Brain; Corticosterone; Ethanol; Humans; Liver; Naloxone; Nicotine; Phenobarbital; Rats; Serotonin; Substance-Related Disorders; Tryptophan

1981
Effects of nicotine and electric footshock on peripheral serotonergic measures and on platelet aggregation in whole blood of rats.
    Life sciences, 1995, Volume: 57, Issue:4

    Topics: Animals; Electroshock; Hydroxyindoleacetic Acid; Male; Nicotine; Platelet Aggregation; Rats; Rats, Wistar; Serotonin; Stress, Physiological; Tryptophan

1995
Changes in the central and peripheral serotonergic system in rats exposed to water-immersion restrained stress and nicotine administration.
    Neuroscience research, 1995, Volume: 23, Issue:3

    Topics: Analysis of Variance; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Hydroxyindoleacetic Acid; Male; Nicotine; Rats; Rats, Wistar; Restraint, Physical; Serotonin; Stress, Physiological; Tryptophan

1995
Changes in blood and plasma serotonergic measurements in rats--effect of nicotine and/or exposure to different stresses.
    Thrombosis research, 1995, Nov-15, Volume: 80, Issue:4

    Topics: Analysis of Variance; Animals; Hydroxyindoleacetic Acid; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Serotonin; Stress, Physiological; Tryptophan

1995
Identification of tryptophan 55 as the primary site of [3H]nicotine photoincorporation in the gamma-subunit of the Torpedo nicotinic acetylcholine receptor.
    FEBS letters, 1998, Feb-20, Volume: 423, Issue:2

    Topics: Animals; Binding Sites; Nicotine; Photoaffinity Labels; Receptors, Nicotinic; Torpedo; Tritium; Tryptophan

1998
Expression of tryptophan decarboxylase and tyrosine decarboxylase genes in tobacco results in altered biochemical and physiological phenotypes.
    Plant physiology, 2000, Volume: 122, Issue:3

    Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Aromatic-L-Amino-Acid Decarboxylases; Chlorogenic Acid; Gene Expression; Genes, Plant; Nicotiana; Nicotine; Phenotype; Phenylalanine; Phenylalanine Ammonia-Lyase; Plants, Genetically Modified; Plants, Toxic; Substrate Specificity; Temperature; Tryptophan; Tyrosine; Tyrosine Decarboxylase

2000
Tryptophan and tyrosine catabolic pattern in neuropsychiatric disorders.
    Neurology India, 2000, Volume: 48, Issue:3

    Topics: Adult; Biogenic Monoamines; Brain Diseases; Brain Neoplasms; Digoxin; Epilepsy, Generalized; Erythrocytes; Fatty Acids, Nonesterified; Female; Glioma; Glycine Agents; Humans; Hydroxymethylglutaryl CoA Reductases; Kynurenic Acid; Magnesium; Male; Microvascular Angina; Middle Aged; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Parkinson Disease; Quinolinic Acid; Schizophrenia; Serum Albumin; Sodium-Potassium-Exchanging ATPase; Strychnine; Tryptophan; Tyrosine; Ubiquinone

2000
Endogenous strychnine, nicotine, and morphine--description of hypo and hyper-strychninergic, nicotinergic and morphinergic state in relation to neuropsychiatric diseases.
    Indian journal of experimental biology, 2000, Volume: 38, Issue:6

    Topics: Adult; Alkaloids; Brain Neoplasms; Chromatography, High Pressure Liquid; Erythrocyte Membrane; Glioma; Humans; Male; Mental Disorders; Middle Aged; Morphine; Neoplasm Proteins; Nervous System Diseases; Nicotine; Sodium-Potassium-Exchanging ATPase; Strychnine; Tryptophan; Tyrosine

2000
Effects of nicotine on head-shakes and tryptophan metabolites.
    Psychopharmacology, 2001, Volume: 153, Issue:3

    Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Head Movements; Hydroxyindoleacetic Acid; Indophenol; Kynurenine; Male; Mice; Nicotine; Nicotinic Agonists; Pyridines; Serotonin; Serotonin Receptor Agonists; Tics; Tryptophan

2001
Cation-pi interactions in ligand recognition by serotonergic (5-HT3A) and nicotinic acetylcholine receptors: the anomalous binding properties of nicotine.
    Biochemistry, 2002, Aug-13, Volume: 41, Issue:32

    Topics: Alkylation; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Cations; Dose-Response Relationship, Drug; Female; Fluorine Radioisotopes; Ligands; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Nicotine; Patch-Clamp Techniques; Pyridinium Compounds; Receptors, Nicotinic; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Receptor Agonists; Static Electricity; Tryptophan; Xenopus laevis

2002
[RESEARCH ON THE METABOLISM OF TRYPTOPHAN IN RATS POISONED, IN AN ACUTE FASHION, WITH NICOTINE AND ITS METABOLITES: COTININE AND DIHYDROMETANICOTINE].
    Bulletin de la Societe de chimie biologique, 1963, Oct-04, Volume: 45

    Topics: Body Fluids; Cotinine; Indoles; Metabolism; Nicotine; Rats; Research; Serotonin; Toxicology; Tryptophan; Urine

1963
[RESEARCH ON TRYPTOPHAN METABOLISM IN THE RAT SUBJECTED TO CHRONIC COTININE POISONING. STUDY OF URINARY ELIMINATION AND DETERMINATION OF CERTAIN INDOLE DERIVATIVES IN THE BRAIN AND INTESTINES].
    Bulletin de la Societe de chimie biologique, 1963, Oct-04, Volume: 45

    Topics: Brain; Cotinine; Indoleacetic Acids; Indoles; Intestines; Metabolism; Neoplasms; Neoplasms, Experimental; Nicotine; Rats; Research; Serotonin; Toxicology; Tryptophan; Urine

1963
[URINARY ELIMINATION OF METABOLITES OF THE TRYPTOPHAN--NICOTINE ACID PATHWAY IN DIABETES DUE TO PANCREATECTOMY IN THE RAT].
    Acta vitaminologica, 1964, Volume: 18

    Topics: Diabetes Mellitus; Metabolism; Niacin; Nicotine; ortho-Aminobenzoates; Pancreatectomy; Pyridines; Rats; Research; Tryptophan; Urine

1964
Hypothalamic digoxin, hemispheric chemical dominance, and mesenteric artery occlusion.
    The International journal of neuroscience, 2003, Volume: 113, Issue:12

    Topics: Aged; Case-Control Studies; Chromatography, High Pressure Liquid; Digoxin; Dolichols; Dominance, Cerebral; Erythrocyte Membrane; Female; Free Radicals; Glycoconjugates; Humans; Hydroxymethylglutaryl CoA Reductases; Hypothalamus; Magnesium; Male; Mesenteric Arteries; Mesenteric Vascular Occlusion; Middle Aged; Nicotine; Sodium-Potassium-Exchanging ATPase; Strychnine; Tryptophan; Tyrosine; Ubiquinone

2003
Using physical chemistry to differentiate nicotinic from cholinergic agonists at the nicotinic acetylcholine receptor.
    Journal of the American Chemical Society, 2005, Jan-12, Volume: 127, Issue:1

    Topics: Acetylcholine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Chemical Phenomena; Chemistry, Physical; Cholinergic Agonists; Crystallography, X-Ray; Hydrogen Bonding; Kinetics; Models, Molecular; Nicotine; Nicotinic Agonists; Pyridines; Receptors, Nicotinic; Static Electricity; Surface Properties; Threonine; Tryptophan; Xenopus laevis

2005
Nicotine binding to brain receptors requires a strong cation-pi interaction.
    Nature, 2009, Mar-26, Volume: 458, Issue:7237

    Topics: Acetylcholine; Animals; Binding Sites; Brain; Cations; Halogenation; Mice; Models, Molecular; Nicotine; Nicotinic Agonists; Oocytes; Organ Specificity; Protein Binding; Protein Conformation; Rats; Receptors, Nicotinic; Smoking; Substance-Related Disorders; Tryptophan; Xenopus laevis

2009
Perinatal effects on in vivo measures of human brain serotonin synthesis in adulthood: a 27-year longitudinal study.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2012, Volume: 22, Issue:6

    Topics: Adult; Birth Weight; Brain; Carbon Radioisotopes; Female; Heart Diseases; Humans; Longitudinal Studies; Lung Diseases; Male; Nicotine; Obstetric Labor Complications; Positron-Emission Tomography; Pregnancy; Prenatal Exposure Delayed Effects; Serotonin; Stress, Psychological; Surveys and Questionnaires; Tryptophan

2012
The moderating influence of nicotine and smoking on resting-state mood and EEG changes in remitted depressed patients during tryptophan depletion.
    Biological psychology, 2013, Volume: 94, Issue:3

    Topics: Adult; Affect; Brain; Depressive Disorder, Major; Double-Blind Method; Electroencephalography; Female; Humans; Male; Nicotine; Serotonin; Smoking; Tryptophan

2013
Nicotine-enhanced oxidation of low-density lipoprotein and its components by myeloperoxidase/H₂O₂/Cl- system.
    Anais da Academia Brasileira de Ciencias, 2015, Volume: 87, Issue:1

    Topics: Adult; Humans; Hydrogen Peroxide; Hypochlorous Acid; Linoleic Acids; Lipoproteins, LDL; Middle Aged; Nicotine; Oxidation-Reduction; Peroxidase; Tryptophan; Vitamin E; Young Adult

2015
Probing for and Quantifying Agonist Hydrogen Bonds in α6β2 Nicotinic Acetylcholine Receptors.
    Biochemistry, 2017, 04-04, Volume: 56, Issue:13

    Topics: Acetylcholine; Animals; Gene Expression; Hydrogen Bonding; Mutagenesis, Site-Directed; Mutation; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Protein Binding; Rats; Receptors, Nicotinic; Thermodynamics; Tryptophan; Xenopus laevis

2017
Increased HPA Axis Activity and Serum Tryptophan in Naswar (Dipping Tobacco) Users: A Case-Control Study.
    Applied psychophysiology and biofeedback, 2017, Volume: 42, Issue:3

    Topics: Adolescent; Adult; Behavior, Addictive; Case-Control Studies; Cotinine; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Nicotine; Pituitary-Adrenal System; Surveys and Questionnaires; Tobacco, Smokeless; Tryptophan

2017
Structure of Gas Phase Monohydrated Nicotine: Implications for Nicotine's Native Structure in the Acetylcholine Binding Protein.
    Journal of the American Chemical Society, 2022, 09-21, Volume: 144, Issue:37

    Topics: Acetylcholine; Binding Sites; Carrier Proteins; Models, Molecular; Nicotine; Protein Subunits; Pyridines; Pyrrolidines; Receptors, Nicotinic; Tryptophan

2022
Electrostatic Contributions to the Binding Free Energy of Nicotine to the Acetylcholine Binding Protein.
    The journal of physical chemistry. B, 2022, 11-03, Volume: 126, Issue:43

    Topics: Acetylcholine; Binding Sites; Carrier Proteins; Ligands; Models, Molecular; Nicotine; Protein Binding; Receptors, Nicotinic; Static Electricity; Tryptophan

2022
Liver tryptophan 2,3-dioxygenase: a determinant of anxiety-like behaviour - studies with chronic nicotine administration in rats.
    Behavioural pharmacology, 2023, 09-01, Volume: 34, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Depression; Dioxygenases; Female; Liver; Male; Mice; Nicotine; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase

2023