Page last updated: 2024-08-26

nicotine and tacrine

nicotine has been researched along with tacrine in 44 studies

Research

Studies (44)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (4.55)	18.7374
1990's	19 (43.18)	18.2507
2000's	16 (36.36)	29.6817
2010's	6 (13.64)	24.3611
2020's	1 (2.27)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Dansette, PM; Fontana, E; Poli, SM	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahman, M; Holmén, AG; Wan, H	1
Bard, B; Carrupt, PA; Martel, S	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Curtis, MA; Lin, SX; Sperry, J	1
Archer, T; Gillberg, PG; Gordh, T; Hartvig, P; Jansson, I; Post, C; Sottile, A	1
Loiacono, RE; Mitchelson, FJ	1
Cross, AJ; Green, AR; Hunter, AJ; Jones, JA; Murray, TK	1
Riekkinen, M; Riekkinen, P	1
Riekkinen, M; Riekkinen, P; Sirviö, J	2
Clarke, PB; el-Bizri, H; Reuben, M	1
Coull, JT; Sahakian, BJ	1
Nordberg, A	1
Lawrence, AD; Sahakian, BJ	1
Lockhart, BP; Maurice, T; Privat, A	1
Dowling, MH; Paddle, BM	1
Aroviita, L; Kivipelto, M; Riekkinen, M; Riekkinen, P; Taskila, K	1
Coffin, VL; Cohen-Williams, M; Kistler, MK; Smith, RD	1
Nordberg, A; Svensson, AL	1
Asano, T; Ito, S; Nakazato, Y; Ohta, T; Sugawara, T	1
Imoto, M; Ohno, T; Saito, K; Tani, Y; Tsuneyoshi, A	1
Miyake, H; Nanri, M; Watanabe, H; Yamamoto, J	1
Yamamoto, J	1
Ikonen, S; Riekkinen, M; Riekkinen, P	1
Beyreuther, K; Emilien, G; Maloteaux, JM; Masters, CL	1
Engeland, C; Ilivitsky, V; Knott, V; Mahoney, C; Mohr, E	3
Engeland, C; Ilivitsky, V; Knott, VJ; Mahoney, C; Mohr, E	1
Gong, ZH; Meyerson, B; Nordberg, A; Svensson, AL; Tian, JY; Zhang, X	1
BLEIBERG, MJ	1
Caricati-Neto, A; D'angelo, LC; Garcia, AG; Hyppolito Jurkiewicz, N; Jurkiewicz, A; Reuter, H	1
Bermudez, I; Groot-Kormelink, PJ; Smulders, CJ; van Kleef, RG; Vijverberg, HP; Zwart, R	1
Auber, A; Chiamulera, C; Giarola, A	1
Nath, C; Patro, IK; Saxena, G	1

Reviews

3 review(s) available for nicotine and tacrine

Article	Year
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Current drug metabolism, 2005, Volume: 6, Issue:5 Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic	2005
Pyridine alkaloids with activity in the central nervous system. Bioorganic & medicinal chemistry, 2020, 12-15, Volume: 28, Issue:24 Topics: Alkaloids; Amphibians; Animals; Bacteria; Central Nervous System Diseases; Fungi; Nicotine; Plants; Pyridines; Receptors, Nicotinic	2020
Prospects for pharmacological intervention in Alzheimer disease. Archives of neurology, 2000, Volume: 57, Issue:4 Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspartic Acid Endopeptidases; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Endopeptidases; Hippocampus; Humans; Indans; N-Methylaspartate; Nerve Growth Factors; Nicotine; Piperidines; Tacrine	2000

Trials

5 trial(s) available for nicotine and tacrine

Article	Year
Tetrahydroaminoacridine (THA) in Alzheimer's disease: an assessment of attentional and mnemonic function using CANTAB. Acta neurologica Scandinavica. Supplementum, 1993, Volume: 149 Topics: Activities of Daily Living; Alzheimer Disease; Attention; Cross-Sectional Studies; Double-Blind Method; Drug Therapy, Computer-Assisted; Female; Humans; Male; Memory; Neuropsychological Tests; Nicotine; Physostigmine; Placebos; Reaction Time; Tacrine; Treatment Outcome	1993
Acute nicotine administration in Alzheimer's disease: an exploratory EEG study. Neuropsychobiology, 2000, Volume: 41, Issue:4 Topics: Administration, Oral; Aged; Aged, 80 and over; Alpha Rhythm; Alzheimer Disease; Beta Rhythm; Brain Mapping; Cholinesterase Inhibitors; Cross-Over Studies; Delta Rhythm; Double-Blind Method; Electroencephalography; Female; Humans; Male; Middle Aged; Nicotine; Nicotinic Agonists; Pilot Projects; Polymethacrylic Acids; Polyvinyls; Tacrine; Theta Rhythm; Tobacco Use Cessation Devices; Treatment Outcome	2000
Acute nicotine effects on auditory sensory memory in tacrine-treated and nontreated patients with Alzheimer's disease: an event-related potential study. Pharmacology, biochemistry, and behavior, 2002, Volume: 72, Issue:1-2 Topics: Acoustic Stimulation; Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Cross-Over Studies; Double-Blind Method; Evoked Potentials, Auditory; Female; Humans; Male; Memory; Middle Aged; Nicotine; Tacrine	2002
Effects of acute nicotine administration on cognitive event-related potentials in tacrine-treated and non-treated patients with Alzheimer's disease. Neuropsychobiology, 2002, Volume: 45, Issue:3 Topics: Administration, Oral; Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Double-Blind Method; Event-Related Potentials, P300; Evoked Potentials, Auditory; Evoked Potentials, Visual; Female; Humans; Male; Middle Aged; Nicotine; Nootropic Agents; Tacrine	2002
Nicotine and sensory memory in Alzheimer's disease: an event-related potential study. Brain and cognition, 2002, Volume: 49, Issue:2 Topics: Acoustic Stimulation; Aged; Alzheimer Disease; Central Nervous System Stimulants; Cholinesterase Inhibitors; Contingent Negative Variation; Cross-Over Studies; Double-Blind Method; Evoked Potentials, Auditory; Female; Humans; Male; Mental Processes; Middle Aged; Nicotine; Nicotinic Agonists; Polymethacrylic Acids; Polyvinyls; Reaction Time; Tacrine; Tobacco Use Cessation Devices	2002

Other Studies

36 other study(ies) available for nicotine and tacrine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography. Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10 Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Behavioral effects after intrathecal administration of cholinergic receptor agonists in the rat. Psychopharmacology, 1990, Volume: 100, Issue:4 Topics: Alkaloids; Animals; Azocines; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mecamylamine; Motor Activity; Nicotine; Nociceptors; Parasympathomimetics; Physostigmine; Quinolizines; Rats; Rats, Inbred Strains; Reaction Time; Tacrine	1990
Effect of nicotine and tacrine on acetylcholine release from rat cerebral cortical slices. Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 342, Issue:1 Topics: Acetylcholine; Aminoacridines; Animals; Atropine; Cerebral Cortex; Dioxanes; Electric Stimulation; Female; Idazoxan; In Vitro Techniques; Male; Nerve Endings; Nicotine; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Tacrine; Tubocurarine	1990
The cholinergic pharmacology of tetrahydroaminoacridine in vivo and in vitro. British journal of pharmacology, 1989, Volume: 98, Issue:1 Topics: Aminoacridines; Animals; Behavior, Animal; Brain Chemistry; Cholinesterase Inhibitors; Gallamine Triethiodide; In Vitro Techniques; Male; Mice; Myocardium; N-Methylscopolamine; Nicotine; Oxotremorine; Parasympathetic Nervous System; Physostigmine; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Tacrine	1989
Effects of tetrahydroaminoacridine and nicotine in nucleus basalis and serotonin-lesioned rats. European journal of pharmacology, 1995, Jun-06, Volume: 279, Issue:1 Topics: Alzheimer Disease; Analysis of Variance; Animals; Avoidance Learning; Basal Ganglia; Cerebral Cortex; Cholinesterase Inhibitors; Fenclonine; Male; Maze Learning; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Serotonin; Tacrine	1995
Serotonin depletion decreases the therapeutic effect of nicotine, but not THA in medial septal-lesioned rats. Brain research, 1994, Oct-31, Volume: 662, Issue:1-2 Topics: Animals; Avoidance Learning; Brain; Brain Stem; Fenclonine; Male; Maze Learning; Nicotine; Parasympathetic Nervous System; Prosencephalon; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Tacrine	1994
Blockade of nicotinic responses by physostigmine, tacrine and other cholinesterase inhibitors in rat striatum. British journal of pharmacology, 1994, Volume: 111, Issue:3 Topics: Animals; Choline; Cholinesterase Inhibitors; Corpus Striatum; Dopamine; Drug Interactions; In Vitro Techniques; Male; Nicotine; Nicotinic Antagonists; Physostigmine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Synaptic Transmission; Synaptosomes; Tacrine; Tritium	1994
Effect of long-term treatment with tacrine (THA) in Alzheimer's disease as visualized by PET. Acta neurologica Scandinavica. Supplementum, 1993, Volume: 149 Topics: Alzheimer Disease; Cerebrovascular Circulation; Female; Frontal Lobe; Glucose; Humans; Male; Nicotine; Receptors, Muscarinic; Receptors, Nicotinic; Tacrine; Temporal Lobe; Tomography, Emission-Computed; Treatment Outcome	1993
Effects of nicotine on neocortical electrical activity in rats. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2 Topics: Animals; Brain Diseases; Cerebral Cortex; Cholinergic Fibers; Electroencephalography; Electrophysiology; Male; Mecamylamine; Nicotine; Parasympatholytics; Rats; Rats, Wistar; Substantia Innominata; Tacrine	1993
Alzheimer disease, attention, and the cholinergic system. Alzheimer disease and associated disorders, 1995, Volume: 9 Suppl 2 Topics: Alzheimer Disease; Attention; Cholinergic Agents; Humans; Nicotine; Research Design; Tacrine	1995
Amnesia induced in mice by centrally administered beta-amyloid peptides involves cholinergic dysfunction. Brain research, 1996, Jan-15, Volume: 706, Issue:2 Topics: Acetylcholine; Alzheimer Disease; Amnesia; Amyloid beta-Peptides; Animals; Avoidance Learning; Cholinesterase Inhibitors; Injections, Intraventricular; Male; Maze Learning; Mice; Nicotine; Peptide Fragments; Tacrine	1996
Blockade of cardiac nicotinic responses by anticholinesterases. General pharmacology, 1996, Volume: 27, Issue:5 Topics: Acetylcholine; Animals; Atropine; Carbamates; Catecholamines; Cholinesterase Inhibitors; Edrophonium; Female; Guinea Pigs; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Myocardial Contraction; Nicotine; Nicotinic Antagonists; Soman; Tacrine	1996
Depletion of serotonin, dopamine and noradrenaline in aged rats decreases the therapeutic effect of nicotine, but not of tetrahydroaminoacridine. European journal of pharmacology, 1996, Jul-25, Volume: 308, Issue:3 Topics: Aging; Animals; Behavior, Animal; Dopamine; Fenclonine; Frontal Lobe; Male; Nicotine; Norepinephrine; Rats; Rats, Wistar; Serotonin; Tacrine	1996
Cholinergic improvement of a naturally-occurring memory deficit in the young rat. Brain research, 1996, Jan-22, Volume: 707, Issue:1 Topics: Animals; Animals, Newborn; Avoidance Learning; Cholinergic Agents; Dose-Response Relationship, Drug; Male; Memory; Nicotine; Oxotremorine; Pilocarpine; Rats; Rats, Sprague-Dawley; Reaction Time; Tacrine	1996
Tacrine interacts with an allosteric activator site on alpha 4 beta 2 nAChRs in M10 cells. Neuroreport, 1996, Sep-02, Volume: 7, Issue:13 Topics: Alkaloids; Allosteric Site; Animals; Azocines; Cells, Cultured; Chickens; Cycloheximide; Fibroblasts; Gene Expression; Kinetics; Macromolecular Substances; Mecamylamine; Mice; Nicotine; Quinolizines; Receptors, Nicotinic; Recombinant Proteins; Tacrine; Transfection; Tubocurarine	1996
Tacrine inhibits nicotinic secretory and current responses in adrenal chromaffin cells. European journal of pharmacology, 1997, Jan-14, Volume: 319, Issue:1 Topics: Acetylcholine; Animals; Catecholamines; Cholinesterase Inhibitors; Chromaffin Cells; Female; Guinea Pigs; Male; Membrane Potentials; Nicotine; Nicotinic Antagonists; Perfusion; Physostigmine; Tacrine	1997
Nicotinic acetylcholine receptor (nACh-R) agonist-induced changes in brain monoamine turnover in mice. Psychopharmacology, 1997, Volume: 129, Issue:3 Topics: Alkaloids; Animals; Azocines; Binding, Competitive; Brain; Dopamine; Isoxazoles; Male; Mecamylamine; Mice; Mice, Inbred Strains; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Norepinephrine; Pyrrolidines; Quinolizines; Serotonin; Tacrine	1997
Protective effect of GTS-21, a novel nicotinic receptor agonist, on delayed neuronal death induced by ischemia in gerbils. Japanese journal of pharmacology, 1998, Volume: 76, Issue:1 Topics: Animals; Avoidance Learning; Behavior, Animal; Benzylidene Compounds; Brain Ischemia; Cell Death; GABA Modulators; Gerbillinae; Male; Memory; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Pentobarbital; Pyramidal Cells; Pyridines; Tacrine	1998
Effects of nicotine, pilocarpine, and tetrahydroaminoacridine on hippocampal theta waves in freely moving rabbits. European journal of pharmacology, 1998, Oct-23, Volume: 359, Issue:2-3 Topics: Animals; Cerebral Cortex; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electroencephalography; Hippocampus; Male; Muscarinic Agonists; Nicotine; Nicotinic Agonists; Pilocarpine; Rabbits; Tacrine; Theta Rhythm	1998
D-cycloserine, a partial NMDA receptor-associated glycine-B site agonist, enhances reversal learning, but a cholinesterase inhibitor and nicotine has no effect. Neuroreport, 1998, Nov-16, Volume: 9, Issue:16 Topics: Alzheimer Disease; Animals; Antimetabolites; Binding Sites; Cholinesterase Inhibitors; Conditioning, Psychological; Cycloserine; Denervation; Glycine; Maze Learning; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reversal Learning; Septal Nuclei; Tacrine	1998
Chronic treatments with tacrine and (-)-nicotine induce different changes of nicotinic and muscarinic acetylcholine receptors in the brain of aged rat. Journal of neural transmission (Vienna, Austria : 1996), 2002, Volume: 109, Issue:3 Topics: Aging; Animals; Binding Sites; Brain; Bridged Bicyclo Compounds, Heterocyclic; Drug Administration Schedule; Male; Nicotine; Nicotinic Agonists; Parasympathomimetics; Pirenzepine; Pyridines; Radioligand Assay; Rats; Receptors, Muscarinic; Receptors, Nicotinic; Tacrine; Tritium	2002
STRUCTURE-ACTIVITY RELATIONSHIPS FOR INTESTINAL STIMULATION BY TETRAHYDROAMINOACRIDINE (THA) AND 9-ALKYL THA HOMOLOGUES. Life sciences (1962), 1965, Volume: 4 Topics: Acetylcholine; Acridines; Arthroplasty, Replacement, Hip; Ileum; Intestine, Small; Intestines; Methacholine Compounds; Muscle, Smooth; Nicotine; Pharmacology; Rabbits; Research; Salicylates; Structure-Activity Relationship; Tacrine	1965
Enhancement of purinergic neurotransmission by galantamine and other acetylcholinesterase inhibitors in the rat vas deferens. European journal of pharmacology, 2004, Oct-25, Volume: 503, Issue:1-3 Topics: Acetylcholine; Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Donepezil; Drug Synergism; Electric Stimulation; Galantamine; In Vitro Techniques; Indans; Male; Muscle Contraction; Muscle, Smooth; Nicotine; Nicotinic Agonists; Phenylcarbamates; Physostigmine; Piperidines; Rats; Rats, Wistar; Receptors, Purinergic; Rivastigmine; Stimulation, Chemical; Synaptic Transmission; Tacrine; Vas Deferens	2004
Cholinergic drugs potentiate human nicotinic alpha4beta2 acetylcholine receptors by a competitive mechanism. European journal of pharmacology, 2005, Feb-21, Volume: 509, Issue:2-3 Topics: Acetylcholine; Alkaloids; Animals; Atropine; Azocines; Binding, Competitive; Cholinergic Agents; Cholinesterase Inhibitors; Dichlorvos; Dose-Response Relationship, Drug; Female; Galantamine; Humans; Membrane Potentials; Models, Biological; Nicotine; Oocytes; Phenylcarbamates; Physostigmine; Plasmids; Quinolizines; Receptors, Nicotinic; Rivastigmine; Scopolamine; Tacrine; Xenopus laevis	2005
Acetylcholinesterase inhibitors partially generalize to nicotine discriminative stimulus effect in rats. Behavioural pharmacology, 2011, Volume: 22, Issue:1 Topics: Animals; Cholinesterase Inhibitors; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Galantamine; Generalization, Stimulus; Male; Nicotine; Nicotinic Agonists; Physostigmine; Rats; Rats, Sprague-Dawley; Tacrine	2011
ICV STZ induced impairment in memory and neuronal mitochondrial function: A protective role of nicotinic receptor. Behavioural brain research, 2011, Oct-10, Volume: 224, Issue:1 Topics: Analysis of Variance; Animals; Blood Glucose; Brain; Calcium; Caspase 3; Cell Death; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Glutathione; Indans; Injections, Intraventricular; Male; Malondialdehyde; Maze Learning; Memory Disorders; Mitochondria; Motor Activity; Neurons; Nicotine; Piperidines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Nicotinic; Streptozocin; Tacrine	2011