nicotine has been researched along with saccharin in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (14.29) | 18.7374 |
| 1990's | 4 (11.43) | 18.2507 |
| 2000's | 8 (22.86) | 29.6817 |
| 2010's | 16 (45.71) | 24.3611 |
| 2020's | 2 (5.71) | 2.80 |
| Authors | Studies |
|---|---|
| Arezo, S; James, JR; Rosecrans, JA; Villaneuva, HF | 1 |
| Arezo, S; James, JR; Rosecrans, JA; Villanueva, HF | 1 |
| Giugno, L; Ossenkopp, KP | 1 |
| Caton, TM; Etscorn, F; Hagen, LS; Moore, GA; Sanders, DL | 1 |
| Caton, TM; Divine, KK; Etscorn, F; Hagen, LS; Moore, GA; Sanders, DL; Scott, EP | 1 |
| Lichtensteiger, W; Schlumpf, M | 1 |
| Iwamoto, ET; Williamson, EC | 1 |
| Day-Pfeiffer, H; Martin, DC; Martin, JC; Sigman, G | 1 |
| Amit, Z; Kunin, D; Smith, BR | 1 |
| Bowers, BJ; Wehner, JM | 1 |
| Di Chiara, G; Fenu, S; Rivas, E | 1 |
| Bienkowski, P; Korkosz, A; Kostowski, W; Kukwa, A; Plaznik, A; Scinska, A; Taracha, E | 1 |
| Agatsuma, S; Chen, K; Hiroi, N; Lee, M; Seif, I; Shih, JC; Zhu, H | 1 |
| Agatsuma, S; Hiroi, N; Lee, M; Zhu, H | 1 |
| Funk, D; Lê, AD; Li, Z; Shram, MJ | 1 |
| Busse, GD; Riley, AL; Rinker, JA | 1 |
| Bulut, A; Büyükgüngör, O; Karabulut, B; Uçar, I | 1 |
| Bura, SA; Burokas, A; Maldonado, R; Martín-García, E | 1 |
| Brown, ML; Kellar, KJ; Levin, ED; Li, TK; Lumeng, L; McDowell, BE; Paige, MA; Petro, A; Rezvani, AH; Rose, JE; Slade, S; Wells, C; Xiao, Y | 1 |
| Cadoni, C; Di Chiara, G; Fenu, S | 1 |
| Anker, JJ; Carroll, ME | 1 |
| Benavidez, JM; Blednov, YA; Harris, RA; Homanics, GE | 1 |
| Campos, C; Grady, SR; Quik, M | 1 |
| Nashmi, R; Renda, A | 1 |
| Ahmed, SH; Clemens, KJ; Fam, J; Huynh, C | 1 |
| Boehm, SL; Frazee, AM; Kasten, CR | 1 |
| Coen, K; Funk, D; Lê, AD; Loughlin, A | 1 |
| Addy, NA; Hughley, S; Nunes, EJ; Park, J; Silva, P; Walton, SN; Wickham, RJ | 1 |
| Jung, T; Kim, W; Lee, H; Noh, J | 1 |
| Ben Haj Salah, K; Fehrentz, JA; Martinez, J; Rodriguez, JA; Wellman, PJ | 1 |
| Beiter, R; Brunzell, DH; Lynch, WJ; Narmeen, S; Tan, L | 1 |
| Coen, K; Funk, D; Lê, AD; Loughlin, A; Russo, M | 1 |
| Cole, RD; Gould, TJ; Harrington, E; Parikh, V; Wolsh, C; Zimmerman, M | 1 |
| Nazarian, A; O'Dell, LE; Richardson, JR | 1 |
| Bhide, PG; Biederman, J; Cannon, EN; Lowe, SE; McCarthy, DM; Morgan, TJ; Spencer, TJ | 1 |
35 other study(ies) available for nicotine and saccharin
| Article | Year |
|---|---|
Withdrawal from nicotine fails to produce a conditioned taste aversion to saccharine in rats and mice.
Topics: Animals; Avoidance Learning; Male; Mice; Mice, Inbred ICR; Morphine Dependence; Nicotine; Rats; Rats, Inbred Strains; Saccharin; Substance Withdrawal Syndrome | 1990 |
Withdrawal from chronic nicotine fails to produce a conditioned taste aversion to saccharin in rats.
Topics: Animals; Avoidance Learning; Choice Behavior; Conditioning, Psychological; Male; Nicotine; Rats; Rats, Inbred Strains; Saccharin; Substance Withdrawal Syndrome; Taste; Time Factors | 1990 |
Nicotine-induced conditioned taste aversions are enhanced in rats with lesions of the area postrema.
Topics: Animals; Avoidance Learning; Brain Stem; Conditioning, Psychological; Male; Nicotine; Rats; Saccharin; Scopolamine; Taste | 1990 |
Saccharin aversions in hamsters as a result of nicotine injections.
Topics: Animals; Avoidance Learning; Chlorides; Cricetinae; Injections, Intraperitoneal; Lithium; Lithium Chloride; Male; Mesocricetus; Nicotine; Saccharin; Taste; Time Factors | 1986 |
Conditioned saccharin aversions in rats as a result of cutaneous nicotine or intraperitoneal nicotine administered in divided doses.
Topics: Administration, Topical; Animals; Avoidance Learning; Injections, Intraperitoneal; Male; Nicotine; Rats; Rats, Inbred Strains; Saccharin; Taste | 1987 |
Prenatal nicotine affects fetal testosterone and sexual dimorphism of saccharin preference.
Topics: Animals; Choice Behavior; Female; Fetus; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Saccharin; Sex Characteristics; Testosterone | 1985 |
Nicotine-induced taste aversion: characterization and preexposure effects in rats.
Topics: Animals; Avoidance Learning; Dose-Response Relationship, Drug; Hexamethonium Compounds; Male; Mecamylamine; Nicotine; Rats; Rats, Inbred Strains; Saccharin; Taste | 1984 |
Saccharin preferences in food deprived aging rats are altered as a function of perinatal drug exposure.
Topics: Aging; Analysis of Variance; Animals; Body Weight; Drinking; Female; Fetus; Food Deprivation; Food Preferences; Methamphetamine; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Saccharin | 1983 |
Nicotine and ethanol interaction on conditioned taste aversions induced by both drugs.
Topics: Analysis of Variance; Animals; Central Nervous System Depressants; Conditioning, Psychological; Drug Interactions; Ethanol; Ganglionic Stimulants; Male; Nicotine; Rats; Rats, Wistar; Saccharin; Taste | 1999 |
Ethanol consumption and behavioral impulsivity are increased in protein kinase Cgamma null mutant mice.
Topics: Administration, Oral; Alcohol Drinking; Animals; Behavior, Animal; Choice Behavior; Ethanol; Female; Impulsive Behavior; Isoenzymes; Male; Mice; Mice, Mutant Strains; Nicotine; Protein Kinase C; Saccharin; Sex Factors | 2001 |
Differential role of dopamine in drug- and lithium-conditioned saccharin avoidance.
Topics: Analysis of Variance; Animals; Avoidance Learning; Benzazepines; Conditioning, Operant; Dopamine; Dopamine Antagonists; Drug Interactions; Eating; Lithium Chloride; Male; Nicotine; Nicotinic Agonists; Raclopride; Rats; Rats, Sprague-Dawley; Saccharin | 2005 |
Nicotine-induced conditioned taste aversion in the rat: effects of ethanol.
Topics: Animals; Avoidance Learning; Conditioning, Psychological; Ethanol; Male; Nicotine; Rats; Rats, Wistar; Saccharin; Self Administration; Sweetening Agents; Taste | 2006 |
Monoamine oxidase A knockout mice exhibit impaired nicotine preference but normal responses to novel stimuli.
Topics: Administration, Oral; Animals; Behavior, Animal; Conditioning, Psychological; Exploratory Behavior; Habituation, Psychophysiologic; Male; Mice; Mice, Inbred C3H; Mice, Knockout; Monoamine Oxidase; Motor Activity; Nicotine; Quinine; Reward; Saccharin; Self Administration | 2006 |
Pleiotropic impact of constitutive fosB inactivation on nicotine-induced behavioral alterations and stress-related traits in mice.
Topics: Animals; Anxiety; Behavior, Animal; Blotting, Western; Caudate Nucleus; Corticosterone; Cotinine; Dose-Response Relationship, Drug; Female; Food Preferences; Gene Expression Regulation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nicotine; Nucleus Accumbens; Protein Isoforms; Proto-Oncogene Proteins c-fos; Putamen; Quinine; Saccharin | 2007 |
Nicotine self-administration, extinction responding and reinstatement in adolescent and adult male rats: evidence against a biological vulnerability to nicotine addiction during adolescence.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psychological; Female; Male; Nicotine; Nicotinic Agonists; Pregnancy; Rats; Reinforcement Schedule; Saccharin; Self Administration; Sweetening Agents | 2008 |
An assessment of sex differences in nicotine-induced conditioned taste aversions.
Topics: Animals; Avoidance Learning; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Long-Evans; Saccharin; Self Administration; Sex Characteristics; Sweetening Agents; Taste | 2008 |
Crystal structure and EPR studies of mixed ligand complex of cobalt(II) with saccharin and ethylisonicotine.
Topics: Cobalt; Copper; Crystallography, X-Ray; Electrochemistry; Electrodes; Electron Spin Resonance Spectroscopy; Ions; Ligands; Models, Molecular; Molecular Conformation; Nicotine; Saccharin; Silver; Silver Compounds; X-Ray Diffraction | 2008 |
Effects of chronic nicotine on food intake and anxiety-like behaviour in CB(1) knockout mice.
Topics: Animals; Anxiety; Behavior, Animal; Blood Glucose; Body Weight; Cholesterol; Dietary Fats; Drinking; Eating; Energy Intake; Food Preferences; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nicotine; Nicotinic Agonists; Receptor, Cannabinoid, CB1; Saccharin | 2010 |
Effects of sazetidine-A, a selective alpha4beta2 nicotinic acetylcholine receptor desensitizing agent on alcohol and nicotine self-administration in selectively bred alcohol-preferring (P) rats.
Topics: Animals; Azetidines; Dose-Response Relationship, Drug; Drug Administration Schedule; Ethanol; Male; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Pyridines; Rats; Receptors, Nicotinic; Reward; Saccharin; Self Administration | 2010 |
Conditioned saccharin avoidance and sensitization to drugs of abuse.
Topics: Amphetamine; Animals; Avoidance Learning; Cocaine; Dose-Response Relationship, Drug; Illicit Drugs; Male; Morphine; Nicotine; Rats; Rats, Sprague-Dawley; Saccharin | 2010 |
Adolescent nicotine exposure sensitizes cue-induced reinstatement of cocaine seeking in rats bred for high and low saccharin intake.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Extinction, Psychological; Female; Gene-Environment Interaction; Nicotine; Phenotype; Rats; Rats, Sprague-Dawley; Recurrence; Saccharin; Self Administration; Sweetening Agents | 2011 |
Behavioral characterization of knockin mice with mutations M287L and Q266I in the glycine receptor α1 subunit.
Topics: 1-Butanol; Alcohol Drinking; Alcohol Withdrawal Seizures; Amino Acid Substitution; Animals; Behavior, Animal; Central Nervous System Depressants; Conditioning, Classical; Drug Synergism; Eating; Ethanol; Female; Food Preferences; Gene Knock-In Techniques; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Motor Skills; Mutation; N-Methylaspartate; Nicotine; Pentylenetetrazole; Quinine; Receptors, Glycine; Reflex, Righting; Reflex, Startle; Rotarod Performance Test; Saccharin; Seizures; Sex Characteristics; Strychnine; Taste Perception | 2012 |
Multiple CNS nicotinic receptors mediate L-dopa-induced dyskinesias: studies with parkinsonian nicotinic receptor knockout mice.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Central Nervous System; Cotinine; Dopamine; Dyskinesias; Mice; Mice, Knockout; Nicotine; Parkinsonian Disorders; Receptors, Nicotinic; Saccharin | 2013 |
Chronic nicotine pretreatment is sufficient to upregulate α4* nicotinic receptors and increase oral nicotine self-administration in mice.
Topics: Administration, Oral; Animals; Bacterial Proteins; Choice Behavior; Drinking Behavior; GABAergic Neurons; Gene Knock-In Techniques; Hippocampus; Luminescent Proteins; Male; Mice, Inbred C57BL; Mice, Transgenic; Nicotine; Nicotinic Agonists; Perforant Pathway; Receptors, Nicotinic; Saccharin; Self Administration; Tobacco Use Disorder; Up-Regulation; Ventral Tegmental Area | 2014 |
Rats quit nicotine for a sweet reward following an extensive history of nicotine use.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Choice Behavior; Disease Models, Animal; Male; Nicotine; Rats; Rats, Sprague-Dawley; Reward; Saccharin; Sweetening Agents | 2017 |
Developing a model of limited-access nicotine consumption in C57Bl/6J mice.
Topics: Animals; Baclofen; Ethanol; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Models, Animal; Nicotine; Saccharin; Self Administration | 2016 |
Habitual nicotine-seeking in rats following limited training.
Topics: Animals; Conditioning, Operant; Drug-Seeking Behavior; Extinction, Psychological; Lithium Chloride; Male; Nicotine; Rats; Rats, Sprague-Dawley; Reward; Saccharin; Self Administration | 2017 |
Evaluating oral flavorant effects on nicotine self-administration behavior and phasic dopamine signaling.
Topics: Animals; Choice Behavior; Conditioning, Operant; Dopamine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Saccharin; Self Administration; Signal Transduction; Sucrose; Sweetening Agents | 2018 |
Alteration of adolescent aversive nicotine response and anxiety-like behavior in nicotine-exposed rats during late lactation period.
Topics: Age Factors; Analysis of Variance; Animals; Anxiety; Avoidance Learning; Body Weight; Choice Behavior; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Food Preferences; Lactation; Male; Nicotine; Nicotinic Agonists; Quinine; Rats; Rats, Sprague-Dawley; Saccharin | 2018 |
The GHR-R antagonist JMV 2959 neither induces malaise nor alters the malaise property of LiCl in the adult male rat.
Topics: Animals; Appetite; Avoidance Learning; Conditioning, Psychological; Feeding Behavior; Glycine; Lithium Chloride; Male; Nicotine; Psychotropic Drugs; Random Allocation; Rats, Sprague-Dawley; Receptors, Ghrelin; Reinforcement, Psychology; Saccharin; Sodium, Dietary; Taste Perception; Triazoles | 2018 |
Exercise or saccharin during abstinence block estrus-induced increases in nicotine-seeking.
Topics: Animals; Behavior, Animal; Drug-Seeking Behavior; Estrus; Extinction, Psychological; Female; Nicotine; Nicotinic Agonists; Physical Conditioning, Animal; Rats; Saccharin; Self Administration | 2019 |
Effects of alcohol dependence on discrete choice between alcohol and saccharin.
Topics: Alcoholism; Animals; Central Nervous System Depressants; Choice Behavior; Ethanol; Male; Nicotine; Nicotinic Agonists; Rats, Long-Evans; Rats, Sprague-Dawley; Saccharin; Self Administration | 2018 |
Adolescent and adult nicotine exposure differentially impacts oral nicotine and oral saccharin self-administration in mice.
Topics: Administration, Oral; Aging; Animals; Conditioning, Operant; Female; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Reinforcement Schedule; Saccharin; Self Administration; Sex Factors; Sweetening Agents | 2019 |
Examination of nicotine and saccharin reward in the Goto-Kakizaki diabetic rat model.
Topics: Animals; Conditioning, Psychological; Diabetes Mellitus, Type 2; Disease Models, Animal; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Rats, Wistar; Reward; Saccharin; Self Administration; Species Specificity; Sweetening Agents | 2020 |
Transgenerational transmission of behavioral phenotypes produced by exposure of male mice to saccharin and nicotine.
Topics: Animals; Behavior, Animal; Body Weight; Crosses, Genetic; DNA Methylation; Drinking Behavior; Female; Male; Methylphenidate; Mice, Inbred C57BL; Motor Activity; Nicotine; Phenotype; Saccharin; Spermatozoa | 2020 |