nicotine has been researched along with pyrroles in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (32.35) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (32.35) | 29.6817 |
| 2010's | 10 (29.41) | 24.3611 |
| 2020's | 2 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Neurath, G | 1 |
| Ambache, N; Zar, MA | 1 |
| Gorrod, JW; Jenner, P | 1 |
| Corrado, L; Felsenfeld, H; Kubilus, J | 1 |
| Rapoport, H; Rueppel, ML | 1 |
| Hester, JB; Rudzik, AD; Veldkamp, W | 1 |
| Leete, E | 1 |
| Bartolini, A; Bellucci, C; Dei, S; Galeotti, N; Ghelardini, C; Gualtieri, F; Manetti, D; Romanelli, MN; Scapecchi, S; Teodori, E | 1 |
| Anderson, DJ; Binder, D; Krich, S; Mereiter, K; Meyer, MD; Pyerin, M; Ullrich, T | 1 |
| Fang, F; Liu, P; Luo, S; Zhai, H; Zhao, M | 1 |
| Amtage, F; Birthelmer, A; Cassel, JC; Ehret, A; Förster, S; Jackisch, R; Jeltsch, H; Lehmann, O | 1 |
| Okada, S; Shimizu, T; Yokotani, K | 1 |
| BALL, CD; BYERRUM, RU; DEWEY, LJ | 1 |
| BYERRUM, RU; GRIFFITH, T; WU, PH | 1 |
| MATTILA, M | 1 |
| BOWMAN, ER; MCKENNIS, H; SCHWARTZ, SL | 1 |
| Fukasawa, Y; Hou, J; Kidokoro, Y; Kuromi, H; Sakai, T; Ueno, K | 1 |
| Jardemark, K; Konradsson, A; Marcus, MM; Svensson, TH | 1 |
| Doi, T; Nagabukuro, H | 1 |
| Belluardo, N; Fuxe, K; Mauro, A; Mudò, G | 1 |
| Hashimoto, T; Hirai, N; Kajikawa, M | 1 |
| Arai, K; Iwasaki-Sekino, A; Mano-Otagiri, A; Ohata, H; Shibasaki, T | 1 |
| Berrendero, F; de Lecea, L; Maldonado, R; Martín-García, E; Plaza-Zabala, A | 1 |
| Cristalli, G; Di Angelantonio, S; Grassi, F; Limatola, C; Moriconi, C; Piccioni, A; Trettel, F | 1 |
| Brielmaier, J; McDonald, CG; Smith, RF | 1 |
| Barnes, C; Gamaleddin, I; Goldberg, SR; Justinova, Z; Le Foll, B; Le Strat, Y; Pushparaj, A; Yan, Y | 1 |
| Aimiuwu, O; Friedman, TC; Gomez, R; Liu, Y; Lutfy, K; Mangubat, M; Nerio, N; Shin, CS | 1 |
| Manicke, NE; Ouyang, Z; Shen, L; Yang, Q; Zhang, J | 1 |
| Arora, S; Rehni, AK; Singh, TG | 1 |
| Cai, JQ; Cao, XZ; Luo, ZR; Zhang, HM | 1 |
| Abdolhosseini, S; Ghiasvand, A; Heidari, N | 1 |
| Abdolhosseini, S; Ghiasvand, AR; Heidari, N | 1 |
| Cano, M; Gad, M; Green, KN; Leslie, FM; Linker, KE; Tawadrous, P; Wood, MA | 1 |
| Andrade, FJ; Ballester, P; Blondeau, P; Corba, A; Giussani, B; Riu, J; Sierra, AF | 1 |
1 review(s) available for nicotine and pyrroles
| Article | Year |
|---|---|
[Nitrogen compounds of tobacco smoke].
Topics: Acridines; Alkaloids; Alkanes; Amines; Amino Acids; Aniline Compounds; Carbazoles; Cyanates; Indoles; Isoquinolines; Ketones; Niacinamide; Nicotiana; Nicotine; Nicotinic Acids; Nitriles; Nitrites; Nitrosamines; Piperidines; Plants, Toxic; Pyrazines; Pyridines; Pyrroles; Pyrrolidines; Quinolines; Quinoxalines; Smoking | 1969 |
1 trial(s) available for nicotine and pyrroles
| Article | Year |
|---|---|
Effect of atorvastatin on vascular endothelial function in moderately nicotine-dependent smokers.
Topics: Adult; Atorvastatin; Cholesterol, LDL; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Lipids; Lipoproteins, HDL; Male; Middle Aged; Nicotine; Pyrroles; Tobacco Use Disorder; Triglycerides; Vasodilation | 2014 |
32 other study(ies) available for nicotine and pyrroles
| Article | Year |
|---|---|
An inhibitory action of histamine on the guinea-pig ileum.
Topics: Animals; Atropine; Colon; Ethanolamines; Guinea Pigs; Hexamethonium Compounds; Histamine; Histamine H1 Antagonists; Ileum; Imidazoles; In Vitro Techniques; Muscle, Smooth; Nicotine; Phentolamine; Pyrazoles; Pyrroles; Reserpine; Tetany | 1970 |
Comparative in vitro hepatic metabolism of some tertiary N-methyl tobacco alkaloids in various species.
Topics: Alkaloids; Animals; Chromatography, Gas; Chromatography, Paper; Cricetinae; Cyclic N-Oxides; Dealkylation; Female; Guinea Pigs; In Vitro Techniques; Liver; Male; Methylation; Mice; Nicotiana; Nicotine; Oxidation-Reduction; Piperidines; Plants, Toxic; Pyridines; Pyrroles; Rabbits; Rats; Species Specificity; Stereoisomerism; Time Factors | 1973 |
Structural requirements for nicotine and cyclic imine-induced amine release from neoplastic mast cells.
Topics: Amines; Animals; Azetines; Azirines; Cell Line; Chemical Phenomena; Chemistry; Electrons; Hydrogen-Ion Concentration; Imidazoles; Imines; Kinetics; Mast Cells; Mice; Mice, Inbred Strains; Neoplasms; Nicotine; Piperidines; Pyrroles; Pyrrolidines; Serotonin; Solubility; Spectrometry, Fluorescence; Structure-Activity Relationship | 1974 |
Incorporation of 1,3-dimethyl-1-pyrrolinium chloride in Nicotiana glutinosa. Biosynthesis of a substituted nicotine.
Topics: Nicotine; Plants; Pyrroles | 1970 |
Pyrrolo[3,2,1-jk][1,4]benzodiazepines and pyrrolo[1,2,3-ef][1,5]benzodiazepines which have central nervous system activity.
Topics: Animals; Behavior, Animal; Benzazepines; Central Nervous System; Chemical Phenomena; Chemistry; Diazepam; Male; Mice; Muscle Contraction; Nicotine; Pyrroles; Reflex; Seizures | 1970 |
Biosynthesis of the Nicotiana alkaloids. XI. Investigation of tautomerism in N-methyl-delta-pyrrolinium chloride and its incorporation into nicotine.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Chlorides; Nicotiana; Nicotine; Ornithine; Plants, Toxic; Pyrroles | 1967 |
Design, synthesis, and preliminary pharmacological evaluation of 1, 4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic agents.
Topics: Adrenergic alpha-Agonists; Amnesia; Animals; Avoidance Learning; Baclofen; Clonidine; Dose-Response Relationship, Drug; Drug Design; GABA Agonists; Mecamylamine; Mice; Molecular Structure; Muscarinic Antagonists; Nicotine; Nootropic Agents; Piperazines; Piracetam; Pyrroles; Scopolamine | 2000 |
Conformationally constrained nicotines: polycyclic, bridged, and spiro-annulated analogues as novel ligands for the nicotinic acetylcholine receptor.
Topics: Animals; Brain; Bridged-Ring Compounds; Crystallography, X-Ray; In Vitro Techniques; Ligands; Molecular Conformation; Nicotine; Pyrroles; Rats; Receptors, Nicotinic; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship | 2002 |
A facile synthesis of cis-1-methyl-1,2,3,3a,4,8b- hexahydropyrrolo[3,2-f]pyrindine, an annulated nicotine analog.
Topics: Ligands; Molecular Structure; Nicotine; Pyridines; Pyrroles; Receptors, Nicotinic; Substrate Specificity | 2002 |
Neurotransmitter release and its presynaptic modulation in the rat hippocampus after selective damage to cholinergic or/and serotonergic afferents.
Topics: 5,7-Dihydroxytryptamine; Acetylcholine; Adrenergic alpha-Agonists; Animals; Antibodies, Monoclonal; Biogenic Monoamines; Brimonidine Tartrate; Choline O-Acetyltransferase; Cholinergic Agents; Cholinergic Fibers; Electric Stimulation; Hippocampus; Immunotoxins; Male; N-Glycosyl Hydrolases; Neurons, Afferent; Neurotoxins; Nicotine; Nicotinic Agonists; Norepinephrine; Organ Culture Techniques; Pyridines; Pyrroles; Quinoxalines; Rats; Rats, Long-Evans; Ribosome Inactivating Proteins, Type 1; Saporins; Serotonin; Serotonin Agents; Serotonin Receptor Agonists | 2003 |
Extrahypothalamic corticotropin-releasing hormone mediates (-)-nicotine-induced elevation of plasma corticosterone in rats.
Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Cyclooxygenase Inhibitors; Indomethacin; Male; Microdialysis; Nicotine; Norepinephrine; Paraventricular Hypothalamic Nucleus; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Time Factors | 2003 |
The biosynthesis of the pyrrolidine ring of nicotine.
Topics: Biochemical Phenomena; Nicotine; Prostheses and Implants; Pyrroles; Pyrrolidines | 1955 |
Synthesis of pyrrolidine ring of nicotine from several C14-labeled metabolites by Nicotiana rustica.
Topics: Nicotiana; Nicotine; Prostheses and Implants; Pyrroles; Pyrrolidines | 1962 |
PHARMACOLOGICAL PROPERTIES OF SOME PYRROLIDINE N-SUBSTITUTED NORNICOTINE DERIVATIVES.
Topics: Alkaloids; Animals; Anura; Blood Pressure; Blood Pressure Determination; Cats; Cholinesterases; Ganglia; Ganglia, Autonomic; Guinea Pigs; Intestine, Small; Intestines; Muscle, Smooth; Muscles; Myocardium; Nicotine; Pharmacology; Poultry; Pyridines; Pyrroles; Pyrrolidines; Research; Toxicology | 1963 |
ALTERNATE ROUTES IN THE METABOLIC DEGRADATION OF THE PYRROLIDINE RING OF NICOTINE.
Topics: Animals; Butyrates; Chromatography; Dogs; Metabolism; Nicotine; Pyrroles; Pyrrolidines; Rats; Research; Spectrophotometry | 1964 |
Repetitive exposures to nicotine induce a hyper-responsiveness via the cAMP/PKA/CREB signal pathway in Drosophila.
Topics: Animals; Animals, Genetically Modified; Behavior, Animal; Brain Chemistry; Carbazoles; Conditioning, Classical; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dose-Response Relationship, Drug; Drosophila; Drosophila Proteins; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Indoles; Male; Motor Activity; Nicotine; Nicotinic Agonists; Protein Synthesis Inhibitors; Pyrroles; Reflex, Startle; Rolipram; Signal Transduction; Time Factors | 2004 |
The combination of nicotine with the D2 antagonist raclopride or the weak D4 antagonist L-745,870 generates a clozapine-like facilitation of NMDA receptor-mediated neurotransmission in pyramidal cells of the rat medial prefrontal cortex.
Topics: Analysis of Variance; Animals; Dopamine Antagonists; Drug Combinations; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; N-Methylaspartate; Nicotine; Prefrontal Cortex; Pyramidal Cells; Pyridines; Pyrroles; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2005 |
Differential effects of TAK-802, a selective acetylcholinesterase inhibitor, and carbamate acetylcholinesterase inhibitors on contraction of the detrusor smooth muscle of the guinea pig.
Topics: Acetylcholinesterase; Animals; Carbamates; Cholinesterase Inhibitors; Guinea Pigs; Isometric Contraction; Male; Muscle, Smooth; Nicotine; Nicotinic Agonists; Pyrroles; Quinolones; Tissue Culture Techniques; Urinary Bladder | 2005 |
Acute intermittent nicotine treatment induces fibroblast growth factor-2 in the subventricular zone of the adult rat brain and enhances neuronal precursor cell proliferation.
Topics: Animals; Cell Differentiation; Cell Proliferation; Fibroblast Growth Factor 2; Hippocampus; Lateral Ventricles; Male; Nerve Regeneration; Neuronal Plasticity; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyrroles; Rats; Rats, Wistar; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Nicotinic; RNA, Messenger; Stem Cells; Up-Regulation | 2007 |
A PIP-family protein is required for biosynthesis of tobacco alkaloids.
Topics: Alkaloids; Immunoblotting; Molecular Structure; Nicotiana; Nicotine; Nicotinic Acids; Phylogeny; Plant Proteins; Plant Roots; Plants, Genetically Modified; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Nicotine suppresses energy storage through activation of sympathetic outflow to brown adipose tissue via corticotropin-releasing factor type 1 receptor.
Topics: Adipose Tissue, Brown; Animals; Energy Metabolism; Injections, Intraperitoneal; Male; Nicotine; Norepinephrine; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Sympathetic Nervous System | 2009 |
Hypocretins regulate the anxiogenic-like effects of nicotine and induce reinstatement of nicotine-seeking behavior.
Topics: Animals; Anxiety; Arginine Vasopressin; Behavior, Addictive; Benzoxazoles; Conditioning, Operant; Corticotropin-Releasing Hormone; Extinction, Psychological; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Naphthyridines; Neurons; Neuropeptides; Nicotine; Orexin Receptors; Orexins; Paraventricular Hypothalamic Nucleus; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Self Administration; Tobacco Use Disorder; Urea | 2010 |
Adenosine A2A receptor induces protein kinase A-dependent functional modulation of human (alpha)3(beta)4 nicotinic receptor.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Carbazoles; Cells, Cultured; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophysiological Phenomena; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Neurons; Nicotine; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrimidines; Pyrroles; Receptor, Adenosine A2A; Receptors, Nicotinic; Signal Transduction; Superior Cervical Ganglion; Transfection; Triazoles | 2011 |
Effects of acute stress on acquisition of nicotine conditioned place preference in adolescent rats: a role for corticotropin-releasing factor 1 receptors.
Topics: Acute Disease; Age Factors; Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Male; Nicotine; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological | 2012 |
Blockade of dopamine d4 receptors attenuates reinstatement of extinguished nicotine-seeking behavior in rats.
Topics: Animals; Behavior, Animal; Discrimination Learning; Dopamine Antagonists; Drug-Seeking Behavior; Extinction, Psychological; Male; Nicotine; Pyridines; Pyrroles; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, Dopamine D4; Reinforcement, Psychology; Self Administration | 2012 |
Nicotine stimulates secretion of corticosterone via both CRH and AVP receptors.
Topics: Analysis of Variance; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Corticosterone; Corticotropin-Releasing Hormone; Drug Interactions; Indoles; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Peptide Fragments; Pyrimidines; Pyrroles; Pyrrolidines; Receptors, Corticotropin-Releasing Hormone; Receptors, Vasopressin | 2012 |
High throughput paper spray mass spectrometry analysis.
Topics: Animals; Cattle; Chemistry Techniques, Analytical; Indoles; Mass Spectrometry; Nicotine; Paper; Pyrroles; Sunitinib; Time Factors | 2013 |
Ro 32-0432 attenuates mecamylamine-precipitated nicotine withdrawal syndrome in mice.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; G-Protein-Coupled Receptor Kinase 5; Indoles; Male; Maze Learning; Mecamylamine; Mice; Nicotine; Pyrroles; Substance Withdrawal Syndrome | 2013 |
A high area, porous and resistant platinized stainless steel fiber coated by nanostructured polypyrrole for direct HS-SPME of nicotine in biological samples prior to GC-FID quantification.
Topics: Chromatography, Gas; Limit of Detection; Linear Models; Nanostructures; Nicotine; Polymers; Porosity; Pyrroles; Reproducibility of Results; Solid Phase Microextraction; Stainless Steel; Temperature | 2017 |
Comparison of the Conventional and Electroenhanced Direct-Immersion Solid-Phase Microextraction for Sampling of Nicotine in Biological Fluids of the Human Body.
Topics: Body Fluids; Coated Materials, Biocompatible; Humans; Hydrogen-Ion Concentration; Nanostructures; Nicotine; Osmolar Concentration; Polymers; Pyrroles; Reproducibility of Results; Solid Phase Microextraction; Solutions; Temperature; Time Factors | 2018 |
Microglial activation increases cocaine self-administration following adolescent nicotine exposure.
Topics: Aminopyridines; Animals; Chemokine CX3CL1; Cocaine; Disease Models, Animal; Drug-Seeking Behavior; Electronic Nicotine Delivery Systems; Female; Gene Expression Regulation; Male; Microglia; Minocycline; Nicotine; Phenotype; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reinforcement, Psychology; Reward; Self Administration; Synaptophysin | 2020 |
Potentiometric detection of creatinine in the presence of nicotine: Molecular recognition, sensing and quantification through multivariate regression.
Topics: Cations; Creatinine; Nicotine; Potentiometry; Pyrroles | 2022 |