Page last updated: 2024-08-26

nicotine and pyrilamine

nicotine has been researched along with pyrilamine in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19907 (28.00)18.7374
1990's2 (8.00)18.2507
2000's5 (20.00)29.6817
2010's11 (44.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Nezu, J; Oku, A; Sai, Y; Sakamoto, K; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H1
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H1
Caron, G; Ermondi, G1
Ahman, M; Holmén, AG; Wan, H1
Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Lisciani, R; Silvestrini, B1
Ercan, ZS; Türker, RK1
Krstić, MK1
Jenner, P; Marsden, CD; Mayer, JM; Pratt, JA; Repond, C; Stolerman, IP; Testa, B1
Kusunoki, M; Tanaka, C; Taniyama, K1
Eidi, A; Eidi, M; Oryan, S; Parivar, K; Zarrindast, MR1
RANG, HP1
Hao, X; Levin, ED; Perraut, C; Roegge, CS1
Alcayaga, J; Del Rio, R; Fujiwara, K; Iturriaga, R; Koenig, CS; Moya, EA1
Cauley, M; Cousins, V; Hampton, D; Levin, ED; Petro, A; Pruitt, M; Rose, J; Slade, S; Wells, C1
Akanuma, S; Hosoya, K; Kubo, Y; Tega, Y; Terasaki, T1
Jiten Singh, N; Jun, DJ; Kim, D; Kim, DC; Kim, KT; Kim, S; Park, YS; Yun, SJ1
Akanuma, S; Hosoya, K; Kubo, Y; Tega, Y1
Akanuma, S; Hosoya, K; Kubo, Y; Tega, Y; Yuzurihara, C1
Briggs, SA; Hall, BJ; Jaskowski, P; Levin, ED; Morrison, M; Rezvani, AH; Rose, JE; Slade, S; Wells, C1
Akanuma, SI; Ehrhardt, C; Hosoya, KI; Kubo, Y; Tega, Y; Yuzurihara, C1
Chattopadhyay, A; Hall, BJ; Levin, ED; Rezvani, AH; Rose, JE; Slade, S; Wells, C1
Kamei, H; Kawami, M; Nagahiro, M; Takano, M; Yumoto, R1

Other Studies

25 other study(ies) available for nicotine and pyrilamine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:2

    Topics: Animals; Biological Transport, Active; Carrier Proteins; Cell Line; Gene Expression; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Oocytes; Organic Cation Transport Proteins; Quinidine; RNA, Messenger; Symporters; Tetraethylammonium Compounds; Xenopus laevis

1999
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism

1999
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Experimental data suggesting an adrenergic mechanism in the production of parkinsonian symptoms.
    Current therapeutic research, clinical and experimental, 1976, Volume: 20, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Atropine; Clonidine; Female; Fenclonine; Imipramine; Male; Mice; Mice, Inbred Strains; Nicotine; Oxotremorine; Parkinson Disease, Secondary; Phenoxybenzamine; Piloerection; Pyrilamine; Rabbits; Salivation; Sympathetic Nervous System; Trazodone; Tremor

1976
Nicotine is a competitive antagonist for H1-receptors in smooth muscles.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 274, Issue:1

    Topics: Animals; Aorta; Binding, Competitive; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Muscle, Smooth; Muscle, Smooth, Vascular; Nicotine; Norepinephrine; Pyrilamine; Rabbits; Trachea

1985
Pressor response mediated via histamine H1-receptors of the guinea-pig sympathetic ganglia.
    Neuropharmacology, 1988, Volume: 27, Issue:12

    Topics: Animals; Atropine; Blood Pressure; Bretylium Tosylate; Dimethylphenylpiperazinium Iodide; Female; Ganglia, Sympathetic; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Histamine; Hydroxydopamines; Male; Metiamide; Nicotine; Oxidopamine; Pyrilamine; Receptors, Histamine H1; Reserpine

1988
Affinity of pyridylalkylamines for nicotinic, muscarinic and histaminic recognition sites in brain tissue preparations.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:8

    Topics: Amines; Animals; Binding, Competitive; Brain Chemistry; Dexetimide; Guinea Pigs; In Vitro Techniques; Male; Nicotine; Proteins; Pyridines; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Muscarinic; Receptors, Nicotinic

1986
Inhibitory histamine H2-receptor in the guinea-pig urinary bladder.
    European journal of pharmacology, 1984, Oct-01, Volume: 105, Issue:1-2

    Topics: Acetylcholine; Animals; Calcium; Choline; Cimetidine; Diphenhydramine; Electric Stimulation; Female; Guinea Pigs; Histamine; Imidazoles; Impromidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Pyrilamine; Receptors, Histamine; Receptors, Histamine H2; Scopolamine; Tetrodotoxin; Urinary Bladder

1984
Effects of histamine and cholinergic systems on memory retention of passive avoidance learning in rats.
    European journal of pharmacology, 2003, Mar-28, Volume: 465, Issue:1-2

    Topics: Acetylcholine; Animals; Avoidance Learning; Cimetidine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Memory; Muscarinic Antagonists; Nicotine; Pyrilamine; Rats; Rats, Wistar; Reaction Time; Receptors, Cholinergic; Receptors, Histamine; Retention, Psychology; Scopolamine

2003
STIMULANT ACTIONS OF VOLATILE ANAESTHETICS ON SMOOTH MUSCLE.
    British journal of pharmacology and chemotherapy, 1964, Volume: 22

    Topics: Acetylcholine; Anesthetics; Animals; Anti-Allergic Agents; Central Nervous System Stimulants; Chloroform; Cocaine; Epinephrine; Ether; Ethers; Guinea Pigs; Halothane; Hexamethonium Compounds; Histamine; Histamine H1 Antagonists; Ileum; Muscle Contraction; Muscle, Smooth; Nicotine; Pharmacology; Pyrilamine; Research; Trichloroethylene

1964
Histamine H1 receptor involvement in prepulse inhibition and memory function: relevance for the antipsychotic actions of clozapine.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 86, Issue:4

    Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Drug Interactions; Female; Histamine H1 Antagonists; Maze Learning; Memory; Nicotine; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Reflex, Startle

2007
Modulatory effects of histamine on cat carotid body chemoreception.
    Respiratory physiology & neurobiology, 2008, Dec-31, Volume: 164, Issue:3

    Topics: Acetylcholine; Action Potentials; Animals; Carotid Body; Cats; Chemoreceptor Cells; Dose-Response Relationship, Drug; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H3 Antagonists; Hypoxia; In Vitro Techniques; Male; Microscopy, Immunoelectron; Nicotine; Nicotinic Agonists; Piperidines; Pyrilamine; Tyrosine 3-Monooxygenase

2008
Histamine H(1) antagonist treatment with pyrilamine reduces nicotine self-administration in rats.
    European journal of pharmacology, 2011, Jan-10, Volume: 650, Issue:1

    Topics: Animals; Butyrophenones; Drug Administration Schedule; Female; Follow-Up Studies; Food; Histamine; Histamine H1 Antagonists; Infusion Pumps; Injections; Motivation; Nicotine; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Self Administration; Tobacco Use Disorder

2011
Blood-to-brain influx transport of nicotine at the rat blood-brain barrier: involvement of a pyrilamine-sensitive organic cation transport process.
    Neurochemistry international, 2013, Volume: 62, Issue:2

    Topics: Animals; Blood-Brain Barrier; Carrier Proteins; Cations; Cell Line; In Vitro Techniques; Male; Nicotine; Pyrilamine; Rats; Rats, Wistar; Tritium

2013
Pyrilamine inhibits nicotine-induced catecholamine secretion.
    Neurochemistry international, 2014, Volume: 74

    Topics: Animals; Catecholamines; Cattle; Exocytosis; Molecular Docking Simulation; Nicotine; Pyrilamine; Receptors, Nicotinic

2014
Involvement of the H+/organic cation antiporter in nicotine transport in rat liver.
    Drug metabolism and disposition: the biological fate of chemicals, 2015, Volume: 43, Issue:1

    Topics: Animals; Biological Transport; Carrier Proteins; Cations; Hepatocytes; Hydrogen-Ion Concentration; Liver; Male; Nicotine; Organic Cation Transport Proteins; Pyrilamine; Rats; Rats, Wistar

2015
Carrier-Mediated Transport of Nicotine Across the Inner Blood-Retinal Barrier: Involvement of a Novel Organic Cation Transporter Driven by an Outward H(+) Gradient.
    Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:9

    Topics: Animals; Biological Transport; Blood-Retinal Barrier; Carrier Proteins; Cations; Cell Line; Endothelial Cells; Hydrogen; Male; Nicotine; Organic Cation Transport Proteins; Pyrilamine; Rats; Rats, Wistar; Retina; Retinal Vessels; Verapamil

2015
Dextromethorphan interactions with histaminergic and serotonergic treatments to reduce nicotine self-administration in rats.
    Pharmacology, biochemistry, and behavior, 2016, Volume: 142

    Topics: Animals; Benzazepines; Dextromethorphan; Female; Histamine H1 Antagonists; Nicotine; Pyrilamine; Rats; Rats, Sprague-Dawley; Self Administration; Serotonin Receptor Agonists

2016
Functional expression of nicotine influx transporter in A549 human alveolar epithelial cells.
    Drug metabolism and pharmacokinetics, 2016, Volume: 31, Issue:1

    Topics: Adrenergic beta-Agonists; Biological Transport; Cell Line, Tumor; Epithelial Cells; Humans; Nicotine; Organic Cation Transport Proteins; Pulmonary Alveoli; Pyrilamine; Verapamil

2016
Reduction of nicotine self-administration by chronic nicotine infusion with H1 histamine blockade in female rats.
    Psychopharmacology, 2016, Volume: 233, Issue:15-16

    Topics: Administration, Cutaneous; Animals; Behavior, Animal; Female; Histamine H1 Antagonists; Humans; Infusions, Subcutaneous; Nicotine; Nicotinic Agonists; Pyrilamine; Rats; Self Administration

2016
Nicotine transport in lung and non-lung epithelial cells.
    Life sciences, 2017, Nov-01, Volume: 188

    Topics: Biological Transport; Carnitine; Cells, Cultured; Diphenhydramine; Drug Interactions; Epithelial Cells; Humans; Hydrogen-Ion Concentration; Lung; Nicotine; Pyrilamine; Temperature; Tetraethylammonium; Time Factors; Tritium; Valinomycin

2017