nicotine has been researched along with promethazine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (47.37) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 4 (21.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Hayward, JN; Pavasuthipaisit, K | 1 |
| Boulter, J; Connolly, J; Heinemann, SF | 1 |
| Korbonits, D; Leszkovszky, GP | 1 |
| Slivko, SF | 1 |
| Beall, FA; Dalldorf, FG | 1 |
| Hansson, E; Ryrfeldt, A | 1 |
| Brandt, K; Daub, D; Hunger, L; Lehmann, KA | 1 |
| GATLING, RR | 1 |
| AUCLAIR, M; THEVENOT, R | 1 |
| BOVET, D; DUREL, P; LONGO, V | 1 |
19 other study(ies) available for nicotine and promethazine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Vasopressin released by nicotine in the monkey.
Topics: Animals; Arginine Vasopressin; Atropine; Behavior, Animal; Diphenhydramine; Electroencephalography; Eye Movements; Female; Haplorhini; Macaca mulatta; Motor Activity; Nicotine; Osmolar Concentration; Promethazine; Vasopressins | 1976 |
Alpha 4-2 beta 2 and other nicotinic acetylcholine receptor subtypes as targets of psychoactive and addictive drugs.
Topics: Acetylcholine; Animals; Cloning, Molecular; DNA; Neurons; Nicotine; Oocytes; Promethazine; Psychotropic Drugs; Receptors, Nicotinic; RNA; Substance-Related Disorders; Trifluoperazine; Xenopus | 1992 |
[On the pharmacology of new isoquinoline derivatives].
Topics: Anesthetics, Local; Animals; Antihypertensive Agents; Atropine; Barbiturates; Blood Pressure; Central Nervous System; Chlorpromazine; Ganglionic Blockers; Intestines; Isoquinolines; Meprobamate; Mice; Muscle Contraction; Muscles; Nicotine; Promethazine; Rats; Sympatholytics | 1967 |
[The effect of cholinomimetics, biogenic amines and their antagonists on the local anesthetic effect].
Topics: Anesthesia, Local; Animals; Cocaine; Cornea; Diphenhydramine; Diphenylacetic Acids; Epinephrine; Guinea Pigs; Histamine; Nicotine; Pilocarpine; Promethazine; Sensory Receptor Cells; Serotonin; Sympatholytics; Sympathomimetics; Tetracaine | 1967 |
The pathogenesis of the lethal effect of anthrax toxin in the rat.
Topics: Animals; Anthrax; Atropine; Bacillus anthracis; Blood; Capillaries; Electrophoresis; In Vitro Techniques; Lung; Methysergide; Microscopy, Electron; Nicotine; p-Methoxy-N-methylphenethylamine; Phenoxybenzamine; Promethazine; Pulmonary Edema; Rats; Tolazoline; Toxins, Biological | 1966 |
Biliary excretion of quaternary ammonium compounds and tertiary amines in the rat.
Topics: Amines; Anesthetics, Local; Animals; Antidepressive Agents; Atropine; Benzilates; Bile; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Nicotine; Promethazine; Quaternary Ammonium Compounds; Rats; Succinylcholine; Time Factors; Tritium | 1971 |
[Biotransformation of fentanyl. III. Effect of chronic drug exposure on the distribution, metabolism and excretion in the rat].
Topics: Animals; Biotransformation; Central Nervous System Depressants; Dealkylation; Diazepam; Ethanol; Fentanyl; In Vitro Techniques; Male; Nicotine; Promethazine; Rats; Rats, Inbred Strains; Tissue Distribution | 1983 |
EFFECT OF NICOTINE ON CHICK EMBRYO.
Topics: Abnormalities, Drug-Induced; Chick Embryo; Cortisone; Epinephrine; Hematoma; Hemorrhage; Nicotine; Norepinephrine; Pharmacology; Pregnancy; Prochlorperazine; Promazine; Promethazine; Research; Stress, Physiological; Temperature; Tolazoline; Toxicology; Vascular Diseases | 1964 |
[TOXICOLOGY AND PHARMACOLOGY OF AN ORGANIC SOLVENT: DIMETHYL SULFOXIDE].
Topics: Acetylcholine; Barium; Blood Pressure; Dimethyl Sulfoxide; Duodenum; Guinea Pigs; Histamine; Ileum; Kidney; Mice; Muscle, Smooth; Muscles; Nicotine; Papaverine; Pharmacology; Promethazine; Rats; Research; Serotonin; Solvents; Toxicology | 1964 |
[Antagonism of dibenzothiazine derivatives (diparcol, parsidol, phenergan) towards the central effects of nicotine; correspondence with clinical experimentation in Parkinson's disease].
Topics: Empirical Research; Histamine Antagonists; Nicotine; Parkinson Disease; Parkinsonian Disorders; Phenothiazines; Promethazine | 1950 |