Page last updated: 2024-08-26

nicotine and pregnanolone

nicotine has been researched along with pregnanolone in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (20.00)	18.2507
2000's	6 (60.00)	29.6817
2010's	1 (10.00)	24.3611
2020's	1 (10.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Collins, AC; Freund, RK; Luntz-Leybman, V	1
Bullock, AE; Clark, AL; Collins, AC; Grady, SR; Marks, MJ; Robinson, SF; Slobe, BS	1
Charalampopoulos, I; Dermitzaki, E; Gravanis, A; Margioris, AN; Stournaras, C; Tsatsanis, C; Vardouli, L	1
Martín-García, E; Pallarès, M	3
Biggio, G; Brundu, A; Concas, A; Marra, C; Porcu, P; Sogliano, C	1
Chopde, CT; Thakre, PP; Tundulwar, MR; Ugale, RR	1
Cao, W; Duffy, KA; Epperson, CN; Johnson, RL; Kuzma, A; Loughead, J; Morrow, AL; Novick, AM; Sammel, MD; Sofuoglu, M; Strasser, AA	1

Trials

1 trial(s) available for nicotine and pregnanolone

Article	Year
Effect of progesterone administration in male and female smokers on nicotine withdrawal and neural response to smoking cues: role of progesterone conversion to allopregnanolone. Biology of sex differences, 2022, 10-23, Volume: 13, Issue:1 Topics: Cross-Over Studies; Cues; Fatigue; Female; Humans; Neurosteroids; Nicotine; Pregnanolone; Progesterone; Smokers; Smoking; Substance Withdrawal Syndrome	2022

Article

Year

Effect of progesterone administration in male and female smokers on nicotine withdrawal and neural response to smoking cues: role of progesterone conversion to allopregnanolone.

Biology of sex differences, 2022, 10-23, Volume: 13, Issue:1

Topics: Cross-Over Studies; Cues; Fatigue; Female; Humans; Neurosteroids; Nicotine; Pregnanolone; Progesterone; Smokers; Smoking; Substance Withdrawal Syndrome

2022

Other Studies

9 other study(ies) available for nicotine and pregnanolone

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
5 alpha-Pregnan-3 alpha-ol-20-one blocks nicotine-induced seizures and enhances paired-pulse inhibition. European journal of pharmacology, 1990, Aug-28, Volume: 185, Issue:2-3 Topics: Animals; Anticonvulsants; Electric Stimulation; Electrophysiology; Hippocampus; Male; Mice; Mice, Inbred C3H; Nicotine; Pregnanolone; Seizures	1990
Neurosteroids modulate nicotinic receptor function in mouse striatal and thalamic synaptosomes. Journal of neurochemistry, 1997, Volume: 68, Issue:6 Topics: 5-alpha-Dihydroprogesterone; Allosteric Regulation; Animals; Anticonvulsants; Dopamine; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred C3H; Neostriatum; Nicotine; Nicotinic Agonists; Pregnanediones; Pregnanolone; Progesterone; Receptors, Nicotinic; Rubidium Radioisotopes; Synaptosomes; Thalamus; Tritium	1997
Dehydroepiandrosterone sulfate and allopregnanolone directly stimulate catecholamine production via induction of tyrosine hydroxylase and secretion by affecting actin polymerization. Endocrinology, 2005, Volume: 146, Issue:8 Topics: Actins; Animals; Catecholamines; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; DNA Primers; Enzyme Induction; Nicotine; PC12 Cells; Pregnanolone; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tyrosine 3-Monooxygenase; Zona Reticularis	2005
Intrahippocampal nicotine and neurosteroids effects on the anxiety-like behaviour in voluntary and chronic alcohol-drinking rats. Behavioural brain research, 2005, Oct-14, Volume: 164, Issue:1 Topics: Administration, Oral; Alcohol Drinking; Animals; Anti-Anxiety Agents; Anxiety; Drug Interactions; Ethanol; Exploratory Behavior; GABA Agents; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hippocampus; Male; Microinjections; Motor Activity; Nicotine; Nicotinic Agonists; Pregnanolone; Pregnenolone; Random Allocation; Rats; Rats, Wistar; Receptors, GABA-A; Self Medication	2005
Neurosteroids in nicotine and morphine dependence. Psychopharmacology, 2006, Volume: 186, Issue:3 Topics: Analgesics, Opioid; Animals; Cerebral Cortex; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Antagonists; Pregnanolone; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome	2006
Effects of intrahippocampal nicotine and neurosteroid administration on withdrawal in voluntary and chronic alcohol-drinking rats. Alcoholism, clinical and experimental research, 2005, Volume: 29, Issue:9 Topics: Animals; Body Weight; Ethanol; Hippocampus; Male; Motor Activity; Nicotine; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Seizures; Substance Withdrawal Syndrome	2005
The intrahippocampal administration of the neurosteroid allopregnanolone blocks the audiogenic seizures induced by nicotine. Brain research, 2005, Nov-16, Volume: 1062, Issue:1-2 Topics: Acoustic Stimulation; Animals; Anticonvulsants; Cholinergic Fibers; Dose-Response Relationship, Drug; Epilepsy, Reflex; Hippocampus; Male; Microinjections; Nicotine; Pregnanolone; Pregnenolone; Random Allocation; Rats; Rats, Wistar; Receptors, GABA-A; Statistics, Nonparametric	2005
Neurosteroid allopregnanolone attenuates development of nicotine withdrawal behavior in mice. Neuroscience letters, 2013, Apr-29, Volume: 541 Topics: Animals; Anxiety; Finasteride; Indomethacin; Male; Maze Learning; Mice; Motor Activity; Neurotransmitter Agents; Nicotine; Pregnanolone; Progesterone; Substance Withdrawal Syndrome; Time Factors	2013