Page last updated: 2024-08-26

nicotine and prednisolone

nicotine has been researched along with prednisolone in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19906 (23.08)18.7374
1990's2 (7.69)18.2507
2000's10 (38.46)29.6817
2010's8 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Iravani, J; Melville, GN1
Jeffery, PK; Rogers, DF1
Kovács, K; Szijj, I2
Mécs, I; Selye, H; Yeghiayan, E1
Pathak, CL1
Feyerabend, C; Mani, V; Newcombe, RG; Ragunath, K; Rhodes, J; Russell, MA; Thomas, GA; Williams, GT1
Campbell, BJ; Finnie, IA; Milton, JD; Rhodes, JM; Sadek, SK; Taylor, BA; Yu, LG1
Kaklamani, VG; Kaklamanis, PG; Markomichelakis, N1
Courtney, E; Evans, BK; Green, JT; Hawkes, ND; Ingram, JR; Newcombe, RG; Pillai, S; Rhodes, J; Srivastava, ED; Swift, JL; Thomas, GA; Williams, GT1
Hebisawa, A; Kawashima, M; Komiya, K; Kurosaki, Y; Shoji, S; Teramoto, S1
Budny, B; Czarnywojtek, A; Florek, E; Komar-Rychlicka, K; Kurdybacha, P; Miechowicz, I; Ruchala, M; Szczepanek, E; Waligorska-Stachura, J; Wasko, R; Zgorzalewicz-Stachowiak, M1

Trials

3 trial(s) available for nicotine and prednisolone

ArticleYear
Transdermal nicotine compared with oral prednisolone therapy for active ulcerative colitis.
    European journal of gastroenterology & hepatology, 1996, Volume: 8, Issue:8

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Colitis, Ulcerative; Colon; Cotinine; Double-Blind Method; Female; Humans; Male; Middle Aged; Nicotine; Prednisolone; Sigmoidoscopy; Treatment Outcome

1996
Could nicotine be beneficial for Behçet's disease?
    Clinical rheumatology, 2002, Volume: 21, Issue:4

    Topics: Adult; Azathioprine; Behcet Syndrome; Colchicine; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Nicotine; Prednisolone; Prospective Studies; Smoking; Treatment Outcome

2002
A randomized trial of nicotine enemas for active ulcerative colitis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Colitis, Ulcerative; Double-Blind Method; Enema; Female; Humans; Male; Mesalamine; Middle Aged; Nicotine; Prednisolone; Sigmoidoscopy

2005

Other Studies

23 other study(ies) available for nicotine and prednisolone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Effects of drugs and environmental factors on ciliary movement (author's transl)].
    Respiration; international review of thoracic diseases, 1975, Volume: 32, Issue:2

    Topics: Acetylcholine; Acetylcysteine; Adrenergic Agonists; Aminophylline; Ammonium Chloride; Animals; Bronchi; Calcium; Cilia; Codeine; Depression, Chemical; Dose-Response Relationship, Drug; Histamine; Humidity; In Vitro Techniques; Methysergide; Nicotine; Pentobarbital; Phentolamine; Pilocarpine; Potassium; Potassium Iodide; Prednisolone; Rats; Serotonin; Stimulation, Chemical

1975
Inhibition of cigarette smoke-induced airway secretory cell hyperplasia by indomethacin, dexamethasone, prednisolone, or hydrocortisone in the rat.
    Experimental lung research, 1986, Volume: 10, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Body Weight; Cell Count; Dexamethasone; Hydrocortisone; Hyperplasia; Indomethacin; Lung; Male; Nicotiana; Nicotine; Plants, Toxic; Prednisolone; Rats; Rats, Inbred Strains; Smoke; Trachea

1986
[Experimental eosinophilia in rats released by hexadimethrine bromide].
    Folia haematologica (Leipzig, Germany : 1928), 1966, Volume: 86, Issue:3

    Topics: Animals; Bromides; Eosinophilia; Female; Heparin; Heparin Antagonists; Histamine H1 Antagonists; Injections, Intravenous; Insulin; Leukocytosis; Male; Mannomustine; Mast Cells; Nicotine; Prednisolone; Quaternary Ammonium Compounds; Rats; Serotonin

1966
Prevention of nicotine intoxication by catatoxic steroids.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 183, Issue:2

    Topics: Animals; Desoxycorticosterone; Ethylestrenol; Ketones; Nicotine; Oxandrolone; Prednisolone; Pregnanediones; Pregnanes; Progesterone; Rats; Spironolactone; Steroids; Triamcinolone

1970
Revival of isolated hearts stopped with alcohol and glucocorticoids by nicotine and acetylcholine.
    Japanese heart journal, 1973, Volume: 14, Issue:4

    Topics: Acetylcholine; Alcohols; Animals; Anura; Catecholamines; Cortisone; Glucocorticoids; Heart; Heart Rate; Hydrocortisone; In Vitro Techniques; Nicotine; Prednisolone; Rabbits

1973
[The production of an experimental eosinophilia in rats by hexadimethrine bromide (Polybrene)].
    Klinische Wochenschrift, 1966, Sep-01, Volume: 44, Issue:17

    Topics: Animals; Blood Cell Count; Eosinophilia; Eosinophils; Epinephrine; Heparin Antagonists; Insulin; Mechlorethamine; Nicotine; Prednisolone; Quaternary Ammonium Compounds; Rats

1966
Stimulation of colonic mucin synthesis by corticosteroids and nicotine.
    Clinical science (London, England : 1979), 1996, Volume: 91, Issue:3

    Topics: Acetylglucosamine; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Carbenoxolone; Colitis, Ulcerative; Colon; Epithelium; Humans; Hydrocortisone; Mucins; Nicotine; Prednisolone; Stimulation, Chemical

1996
A case of acute eosinophilic pneumonia following short-term passive smoking: an evidence of very high level of urinary cotinine.
    Allergology international : official journal of the Japanese Society of Allergology, 2010, Volume: 59, Issue:4

    Topics: Acute Disease; Biomarkers; Cotinine; Dermatitis, Atopic; Eosinophils; Humans; Lung; Male; Nicotine; Prednisolone; Pulmonary Eosinophilia; Respiratory Insufficiency; Tobacco Smoke Pollution; Tomography, X-Ray Computed; Young Adult

2010
The influence of radioiodine therapy on ocular changes and their relation to urine cotinine level in patients with Graves' Ophthalmopathy.
    Neuro endocrinology letters, 2013, Volume: 34, Issue:3

    Topics: Adult; Chemoradiotherapy; Cotinine; Dose-Response Relationship, Radiation; Female; Glucocorticoids; Graves Ophthalmopathy; Humans; Male; Middle Aged; Nicotine; Nicotinic Agonists; Prednisolone; Smoking; Thyroid Function Tests; Vision Disorders; Young Adult

2013