Compounds > nicotine
Page last updated: 2024-08-26

nicotine and pozanicline

nicotine has been researched along with pozanicline in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (41.67)18.2507
2000's2 (16.67)29.6817
2010's4 (33.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Anderson, DJ; Arneric, SP; Brioni, JD; Buccafusco, JJ; Buckley, MJ; Decker, MW; Donnelly-Roberts, DL; Garvey, DS; Gunn, DE; Holladay, MW; Lin, NH; Marsh, KG; Prendergast, MA; Rodrigues, AD; Ryther, KB; Sullivan, JP; Williams, M1
Dart, MJ; Holladay, MW; Lynch, JK1
Efange, SM; Francesconi, L; Howell, RC; Kung, MP; Papke, RL; Rampersad, MV; Todaro, LJ; Tu, Z; von Hohenberg, K1
Abraham, R; Bhyrapuneni, G; Bogaraju, N; Jasti, V; Mekala, VR; Mohammed, AR; Muddana, N; Nirogi, R; Palacharla, RC; Ravella, SR; Shinde, AK; Subramanian, R; Thentu, JB1
Arneric, SP; Bannon, AW; Brioni, JD; Buccafusco, JJ; Curzon, P; Daanen, JF; Decker, MW; Gunther, KL; Holladay, MW; Jackson, WJ; Li, Y; Lin, NH; Prendergast, MA1
Arneric, SP; Buccafusco, JJ; Decker, MW; Jackson, WJ; Prendergast, MA; Terry, AV1
Arneric, SP; Briggs, CA; Gopalakrishnan, M; McKenna, DG; Monteggia, LM; Roch, JM; Sullivan, JP; Touma, E1
Decker, MW; Man, K; Parikh, V; Sarter, M1
Angelakos, CC; Meyer, PJ; Paolone, G; Robinson, TE; Sarter, M1
Blendy, JA; Turner, JR; Yohn, NL1
Arreola, AC; Kimmey, BA; Lee, AM; Schmidt, HD1
Connor, DA; Gould, TJ; Yildirim, E1

Reviews

1 review(s) available for nicotine and pozanicline

ArticleYear
Neuronal nicotinic acetylcholine receptors as targets for drug discovery.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Acetylcholine; Animals; Binding Sites; Dopamine; Drug Design; Humans; Molecular Structure; Nervous System; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Structure-Activity Relationship

1997

Other Studies

11 other study(ies) available for nicotine and pozanicline

ArticleYear
Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties.
    Journal of medicinal chemistry, 1997, Jan-31, Volume: 40, Issue:3

    Topics: Administration, Oral; Alkaloids; Animals; Anti-Anxiety Agents; Azocines; Biological Availability; Bungarotoxins; Cell Line; Cognition; Dogs; Haplorhini; Humans; Hypothermia; Isoxazoles; Ligands; Maze Learning; Mice; Molecular Structure; Psychomotor Performance; Pyrrolidines; Quinolizines; Receptors, Nicotinic; Rubidium; Structure-Activity Relationship

1997
2-(2-Piperidyl)- and 2-(2-pyrrolidyl)chromans as nicotine agonists: synthesis and preliminary pharmacological characterization.
    Journal of medicinal chemistry, 2001, Dec-20, Volume: 44, Issue:26

    Topics: Acetylcholine; Animals; Cerebral Cortex; Chromans; Cloning, Molecular; Corpus Striatum; Crystallography, X-Ray; Dopamine; Humans; In Vitro Techniques; Nicotine; Nicotinic Agonists; Oocytes; Piperidines; Pyrrolidines; Radioligand Assay; Rats; Receptors, Nicotinic; Structure-Activity Relationship; Synaptosomes; Xenopus laevis

2001
Discovery and Development of 3-(6-Chloropyridine-3-yloxymethyl)-2-azabicyclo[3.1.0]hexane Hydrochloride (SUVN-911): A Novel, Potent, Selective, and Orally Active Neuronal Nicotinic Acetylcholine α4β2 Receptor Antagonist for the Treatment of Depression.
    Journal of medicinal chemistry, 2020, 03-26, Volume: 63, Issue:6

    Topics: Administration, Oral; Animals; Antidepressive Agents; Bridged Bicyclo Compounds; Depression; Halogenation; Humans; Male; Nicotinic Antagonists; Pyridines; Rats; Rats, Wistar; Receptors, Nicotinic

2020
ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride]: II. A novel cholinergic channel modulator with effects on cognitive performance in rats and monkeys.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:1

    Topics: Animals; Avoidance Learning; Cholinergic Agents; Cognition; Discrimination Learning; Female; Ion Channels; Macaca nemestrina; Male; Maze Learning; Nicotine; Pyridines; Pyrrolidines; Rats; Receptors, Nicotinic

1997
Central nicotinic receptor agonists ABT-418, ABT-089, and (-)-nicotine reduce distractibility in adult monkeys.
    Psychopharmacology, 1998, Volume: 136, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Attention; Cholinergic Agents; Dose-Response Relationship, Drug; Female; Isoxazoles; Macaca mulatta; Macaca nemestrina; Male; Mental Recall; Nicotine; Nicotinic Agonists; Photic Stimulation; Pyridines; Pyrrolidines; Receptors, Nicotinic

1998
Gain of function mutation of the alpha7 nicotinic receptor: distinct pharmacology of the human alpha7V274T variant.
    European journal of pharmacology, 1999, Feb-05, Volume: 366, Issue:2-3

    Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amino Acid Substitution; Animals; Atropine; Choline; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Genetic Variation; Humans; Lobeline; Mecamylamine; Membrane Potentials; Muscarinic Antagonists; Mutation; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oocytes; Pyridines; Pyrrolidines; Receptors, Nicotinic; Threonine; Tubocurarine; Valine; Xenopus

1999
Glutamatergic contributions to nicotinic acetylcholine receptor agonist-evoked cholinergic transients in the prefrontal cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Apr-02, Volume: 28, Issue:14

    Topics: Acetylcholine; Analysis of Variance; Animals; Choline; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electrochemistry; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Male; Mecamylamine; Neostigmine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex; Pyridines; Pyrrolidines; Quinoxalines; Rats; Sodium Channel Blockers; Tetrodotoxin; Valine

2008
Cholinergic control over attention in rats prone to attribute incentive salience to reward cues.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, May-08, Volume: 33, Issue:19

    Topics: Acetylcholine; Amphetamine; Animals; Attention; Cholinergic Agonists; Conditioning, Classical; Cues; Dopamine Uptake Inhibitors; Female; Male; Microdialysis; Motivation; Nicotine; Principal Component Analysis; Pyridines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reward; Time Factors; Video Recording

2013
Activation of α4β2*/α6β2* nicotinic receptors alleviates anxiety during nicotine withdrawal without upregulating nicotinic receptors.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 349, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Brain; Drug Partial Agonism; Indoles; Male; Mice; Nicotine; Nicotinic Agonists; Pyridines; Pyrrolidines; Quinuclidines; Radioligand Assay; Receptors, Nicotinic; Substance Withdrawal Syndrome; Time Factors; Up-Regulation

2014
Administration of the nicotinic acetylcholine receptor agonists ABT-089 and ABT-107 attenuates the reinstatement of nicotine-seeking behavior in rats.
    Behavioural brain research, 2014, Nov-01, Volume: 274

    Topics: Analysis of Variance; Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Indoles; Male; Nicotine; Nicotinic Agonists; Pyridines; Pyrrolidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reward; Self Administration; Sucrose

2014
ABT-089, but not ABT-107, ameliorates nicotine withdrawal-induced cognitive deficits in C57BL6/J mice.
    Behavioural pharmacology, 2015, Volume: 26, Issue:3

    Topics: Animals; Cognition; Conditioning, Psychological; Cues; Dose-Response Relationship, Drug; Drug Partial Agonism; Fear; Hippocampus; Indoles; Learning; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Pyridines; Pyrrolidines; Quinuclidines; Receptors, Nicotinic; Substance Withdrawal Syndrome; Tobacco Use Disorder

2015