nicotine has been researched along with pnu-282987 in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (20.69) | 29.6817 |
| 2010's | 21 (72.41) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Danielson, UH; de Esch, IJ; de Kloe, GE; Geitmann, M; Irth, H; Källblad, P; Leurs, R; Nahar, T; Retra, K; Smit, AB; van Elk, R; van Muijlwijk-Koezen, JE | 1 |
| Bellucci, C; Dei, S; Kudryavtsev, D; Manetti, D; Romanelli, MN; Shelukhina, I; Spirova, E; Teodori, E; Tsetlin, V; Varani, K | 1 |
| Fang, X; Gupta, N; Lee, JW; Matthay, MA; Matthay, ZA; Mednick, G; Su, X; Uchida, T | 1 |
| Briggs, CA; Gopalakrishnan, M; Grønlien, JH; Håkerud, M; Malysz, J; Thorin-Hagene, K; Ween, H | 1 |
| Anderson, DJ; Bertrand, D; Bunnelle, W; Du, J; Gopalakrishnan, M; Marguerat, A; Surber, B; Surowy, C; Tribollet, E | 1 |
| Abel, S; Anderson, DJ; Bitner, RS; Blomme, EA; Gopalakrishnan, M; Li, J; Nikkel, AL; Waring, JF | 1 |
| Chida, Y; Hiramoto, T; Kubo, C; Sonoda, J; Sudo, N; Yoshihara, K | 1 |
| Duan, JL; Li, DJ; Shen, FM; Su, DF; Tang, Q; Xi, T | 1 |
| Alvarez, J; del Barrio, L; Egea, J; León, R; López, MG; Montero, M; Romero, A; Ruiz, A | 1 |
| Amagase, K; Hashimura, H; Kato, S; Kawahara, R; Takeuchi, K; Yasuda, M | 1 |
| Dar, MS; Soderstrom, K; Taslim, N | 1 |
| Saeed Dar, M; Taslim, N | 1 |
| Calixto, JB; Cola, M; Costa, R; Manjavachi, MN; Motta, EM | 1 |
| Garg, PK; Garg, S; Gould, RW; Nader, MA | 1 |
| Geyer, MA; Meves, JM; Young, JW | 1 |
| Iwamoto, K; Linn, CL; Linn, DM; Mata, D | 1 |
| Furihata, M; Iketani, M; Kakinuma, Y; Kurabayashi, A; Kurabayashi, M; Noguchi, T; Oikawa, S; Okazaki, K; Sato, T | 1 |
| Cao, QA; Dai, QY; Guo, ZZ; Li, ZZ; Wu, LL; Yao, HL; Zhang, Z; Zhu, YJ | 1 |
| Grayson, B; Harte, MK; Marsh, S; McLean, SL; Neill, JC; Zarroug, SH | 1 |
| Carroll, FI; Freitas, KC; Negus, SS | 1 |
| Akyüz, L; Böttcher, C; da Costa Goncalves, AC; Dames, C; Dirnagl, U; Engel, O; Herold, S; Meisel, A; Meisel, C; Priller, J; Thielke, M; Volk, HD; Winek, K | 1 |
| Berg, DK; Cao, SX; Chen, XJ; Chen, Z; Duan, S; He, HY; Li, XM; Shen, CJ; Sun, P; Wang, XD; Yang, CH; Zhang, Y | 1 |
| de Moura, FB; McMahon, LR | 1 |
| Bagdas, D; Carroll, FI; Damaj, MI; Greenwald, M; Jackson, A; Lichtman, AH; Miles, MF; Muldoon, PP | 1 |
| Chalfant, V; Espinoza-Derout, J; Friedman, TC; Hasan, MK; Lee, DL; Lee, ML; Liu, Y; Lutfy, K; Mahata, SK; Sims, C; Sinha-Hikim, AP; Sinha-Hikim, I; Ume, A | 1 |
| Damaj, MI; Jackson, A; Papke, RL | 1 |
| Arias, HR; Biala, G; Budzynska, B; Jozwiak, K; Michalak, A; Targowska-Duda, KM | 1 |
| Fukunaga, K; Inagaki, R; Moriguchi, S; Sakagami, H; Shibata, M; Yi, L | 1 |
| Inoue, S; Mizutani, Y; Nagata, H; Takagi, N | 1 |
29 other study(ies) available for nicotine and pnu-282987
| Article | Year |
|---|---|
Surface plasmon resonance biosensor based fragment screening using acetylcholine binding protein identifies ligand efficiency hot spots (LE hot spots) by deconstruction of nicotinic acetylcholine receptor α7 ligands.
Topics: Animals; Aplysia; Binding Sites; Binding, Competitive; Biosensing Techniques; Carbamates; Carrier Proteins; Humans; Ligands; Lymnaea; Models, Molecular; Pyridines; Quinuclidines; Radioligand Assay; Receptors, Nicotinic; Structure-Activity Relationship; Surface Plasmon Resonance | 2010 |
New quinoline derivatives as nicotinic receptor modulators.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bridged Bicyclo Compounds; Calcium; Cell Line, Tumor; Humans; Mice; Molecular Docking Simulation; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Quinolines; Rats; Receptors, Nicotinic; Xenopus | 2016 |
Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; Capillary Permeability; Cell Differentiation; Cells, Cultured; Choline; Cytokines; Epithelial Cells; Extravascular Lung Water; Humans; Hydrochloric Acid; Lung; Macrophages, Alveolar; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; NF-kappa B; Nicotine; Nicotinic Agonists; Rats; Receptors, Nicotinic; Respiratory Distress Syndrome | 2007 |
Distinct profiles of alpha7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes.
Topics: Acetylcholine; Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Benzylidene Compounds; Bridged Bicyclo Compounds; Calcium; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Genistein; Humans; Indoles; Isoxazoles; Kidney; Microinjections; Naphthalenes; Nicotine; Nicotinic Antagonists; Oocytes; Patch-Clamp Techniques; Phenylurea Compounds; Protein-Tyrosine Kinases; Pyridines; Quinolines; Receptors, Cholinergic; Receptors, Nicotinic; Sensitivity and Specificity; Sulfonamides; Xenopus laevis | 2007 |
[3H]A-585539 [(1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo[2.2.1]heptane], a novel high-affinity alpha7 neuronal nicotinic receptor agonist: radioligand binding characterization to rat and human brain.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Bungarotoxins; Cell Line; Humans; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Spiro Compounds | 2008 |
Analysis of gene expression profiles in rat hippocampus following treatment with nicotine and an alpha7 nAChR selective agonist.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; Gene Expression Profiling; Hippocampus; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Transcription, Genetic | 2008 |
The hepatic vagus nerve attenuates Fas-induced apoptosis in the mouse liver via alpha7 nicotinic acetylcholine receptor.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antioxidants; Apoptosis; Benzamides; Bridged Bicyclo Compounds; Caspase 3; Diphosphonates; Disease Models, Animal; Dose-Response Relationship, Drug; fas Receptor; Hepatitis; Kupffer Cells; Liver; Male; Metalloporphyrins; Methane; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Reactive Oxygen Species; Receptors, Nicotinic; Reproducibility of Results; Signal Transduction; Time Factors; Vagotomy; Vagus Nerve | 2008 |
Overexpressed alpha7 nicotinic acetylcholine receptor inhibited proinflammatory cytokine release in NIH3T3 cells.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; Cytokines; Fibroblasts; Gene Expression; Inflammation Mediators; Macrophages, Peritoneal; Mice; Nicotine; Nicotinic Agonists; NIH 3T3 Cells; Rats; Receptors, Nicotinic | 2009 |
Calcium signalling mediated through α7 and non-α7 nAChR stimulation is differentially regulated in bovine chromaffin cells to induce catecholamine release.
Topics: Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; Calcium Signaling; Catecholamines; Cattle; Cells, Cultured; Choline; Chromaffin Cells; Exocytosis; Fluorescent Dyes; Nicotine; Nicotinic Agonists; Receptors, Nicotinic | 2011 |
Activation of α7 nicotinic acetylcholine receptors ameliorates indomethacin-induced small intestinal ulceration in mice.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Benzamides; Bridged Bicyclo Compounds; Gene Expression Regulation, Enzymologic; Indomethacin; Intestine, Small; Macrophages; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nitric Oxide Synthase Type II; Peroxidase; Receptors, Nicotinic; RNA, Messenger; Tyrosine; Ulcer | 2011 |
Role of mouse cerebellar nicotinic acetylcholine receptor (nAChR) α(4)β(2)- and α(7) subtypes in the behavioral cross-tolerance between nicotine and ethanol-induced ataxia.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Benzamides; Bridged Bicyclo Compounds; Cerebellar Ataxia; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Ethanol; Injections, Intraventricular; Male; Mice; Motor Activity; Nicotine; Nicotinic Agonists; Nitrates; Nitrites; Psychomotor Performance; Receptors, Nicotinic; Time Factors | 2011 |
The role of nicotinic acetylcholine receptor (nAChR) α7 subtype in the functional interaction between nicotine and ethanol in mouse cerebellum.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Ataxia; Benzamides; Bridged Bicyclo Compounds; Cerebellum; Dose-Response Relationship, Drug; Ethanol; Infusions, Intraventricular; Male; Mice; Nicotine; Receptors, Nicotinic | 2011 |
Activation of the alpha-7 nicotinic acetylcholine receptor (α7 nAchR) reverses referred mechanical hyperalgesia induced by colonic inflammation in mice.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; Behavior, Animal; Benzamides; Bridged Bicyclo Compounds; Colitis; Dose-Response Relationship, Drug; Drug Antagonism; Hyperalgesia; Male; Mice; Mice, Inbred Strains; Molecular Targeted Therapy; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pain Threshold; Pain, Referred; Random Allocation; Receptors, Nicotinic | 2012 |
Effects of nicotinic acetylcholine receptor agonists on cognition in rhesus monkeys with a chronic cocaine self-administration history.
Topics: Animals; Behavior, Animal; Benzamides; Benzazepines; Bridged Bicyclo Compounds; Cocaine; Cocaine-Related Disorders; Cognition Disorders; Dopamine Uptake Inhibitors; Hippocampus; Learning; Ligands; Macaca mulatta; Male; Memory, Short-Term; Nerve Tissue Proteins; Neurons; Nicotine; Nicotinic Agonists; Nootropic Agents; Quinoxalines; Receptors, Nicotinic; Reversal Learning; Self Administration; Varenicline | 2013 |
Nicotinic agonist-induced improvement of vigilance in mice in the 5-choice continuous performance test.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Attention; Behavior, Animal; Benzamides; Bridged Bicyclo Compounds; Choice Behavior; Cholinergic Antagonists; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Psychomotor Performance; Pyrrolidines; Receptors, Nicotinic; Scopolamine | 2013 |
Neuroprotection of rat retinal ganglion cells mediated through alpha7 nicotinic acetylcholine receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Apoptosis; Benzamides; Bridged Bicyclo Compounds; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Female; Glutamic Acid; In Situ Nick-End Labeling; Male; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Rats; Rats, Long-Evans; Receptors, Nicotinic; Retina; Retinal Ganglion Cells; Time Factors | 2013 |
Antimuscle atrophy effect of nicotine targets muscle satellite cells partly through an α7 nicotinic receptor in a murine hindlimb ischemia model.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; Cells, Cultured; Gene Expression Regulation; Hindlimb; Ischemia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Muscular Atrophy; Nicotine; Nicotinic Agonists; Satellite Cells, Skeletal Muscle; Vascular Endothelial Growth Factor A | 2014 |
Nicotine-induced upregulation of VCAM-1, MMP-2, and MMP-9 through the α7-nAChR-JNK pathway in RAW264.7 and MOVAS cells.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anthracenes; Aortic Aneurysm; Benzamides; Bridged Bicyclo Compounds; Cell Line; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Nicotine; Smoking; Transcriptional Activation; Vascular Cell Adhesion Molecule-1 | 2015 |
Nicotinic α7 and α4β2 agonists enhance the formation and retrieval of recognition memory: Potential mechanisms for cognitive performance enhancement in neurological and psychiatric disorders.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Benzamides; Bridged Bicyclo Compounds; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Indans; Locomotion; Mental Recall; Nicotine; Nicotinic Agonists; Piperidines; Rats; Recognition, Psychology; Retention, Psychology; Risperidone | 2016 |
Effects of nicotinic acetylcholine receptor agonists in assays of acute pain-stimulated and pain-depressed behaviors in rats.
Topics: Acute Disease; Analgesics; Animals; Azetidines; Behavior, Animal; Benzamides; Brain; Bridged Bicyclo Compounds; Conditioning, Operant; Electric Stimulation; Male; Nicotine; Nicotinic Agonists; Pain; Pyridines; Rats, Sprague-Dawley; Self Stimulation | 2015 |
Cholinergic Pathway Suppresses Pulmonary Innate Immunity Facilitating Pneumonia After Stroke.
Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Heart Rate; Immunity, Innate; Infarction, Middle Cerebral Artery; Lung; Macrophages, Alveolar; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Nicotinic Agonists; Parasympathetic Nervous System; Parasympathomimetics; Pneumonia; Receptors, Nicotinic; Respiratory Mucosa; Signal Transduction; Stroke; Vagotomy | 2015 |
Loss of MeCP2 in cholinergic neurons causes part of RTT-like phenotypes via α7 receptor in hippocampus.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; Caudate Nucleus; Cholinergic Neurons; Disease Susceptibility; Gene Deletion; Hippocampus; Male; Methyl-CpG-Binding Protein 2; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Nicotine; Phenotype; Prosencephalon; Rett Syndrome; Seizures; Signal Transduction | 2016 |
The contribution of α4β2 and non-α4β2 nicotinic acetylcholine receptors to the discriminative stimulus effects of nicotine and varenicline in mice.
Topics: Aconitine; Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Animals; Azocines; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Dihydro-beta-Erythroidine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Hypnotics and Sedatives; Ibogaine; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Midazolam; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Quinolizines; Receptors, Nicotinic; Varenicline | 2017 |
In vivo interactions between α7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α: Implication for nicotine dependence.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Anesthetics, Local; Animals; Benzamides; Bridged Bicyclo Compounds; Cocaine; Conditioning, Operant; Disease Models, Animal; Fenofibrate; Hypolipidemic Agents; Male; Mice; Mice, Inbred ICR; Nicotine; Nicotinic Agonists; Oxazoles; PPAR alpha; Pyrimidines; Self Administration; Substance Withdrawal Syndrome; Tobacco Use Disorder; Tyrosine | 2017 |
α7-Nicotinic Acetylcholine Receptor Agonist Ameliorates Nicotine Plus High-Fat Diet-Induced Hepatic Steatosis in Male Mice by Inhibiting Oxidative Stress and Stimulating AMPK Signaling.
Topics: alpha7 Nicotinic Acetylcholine Receptor; AMP-Activated Protein Kinases; Animals; Benzamides; Bridged Bicyclo Compounds; Diet, High-Fat; Fatty Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Nicotine; Oxidative Stress; Signal Transduction | 2018 |
Pharmacological modulation of the α7 nicotinic acetylcholine receptor in a mouse model of mecamylamine-precipitated nicotine withdrawal.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Infusion Pumps; Male; Mecamylamine; Mice; Mice, Inbred ICR; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Substance Withdrawal Syndrome | 2018 |
3-Furan-2-yl-N-p-tolyl-acrylamide, a highly selective positive allosteric modulator of α7 nicotinic receptors, produces anxiolytic-like activity in mice.
Topics: Acrylamides; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anxiety; Behavior, Animal; Benzamides; Bridged Bicyclo Compounds; Disease Models, Animal; Drug Interactions; Furans; Male; Mice; Nicotine; Nicotinic Agonists | 2019 |
Nicotine Rescues Depressive-like Behaviors via α7-type Nicotinic Acetylcholine Receptor Activation in CaMKIV Null Mice.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Benzamides; Benzylidene Compounds; Brain-Derived Neurotrophic Factor; Bridged Bicyclo Compounds; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Cyclic AMP Response Element-Binding Protein; Dentate Gyrus; Depression; Extracellular Signal-Regulated MAP Kinases; Mice, Knockout; Models, Biological; Neurogenesis; Nicotine; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines | 2020 |
Nicotine affects tight junction barriers via alpha7 nicotine-like acetylcholine receptor in keratinocytes.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Benzamides; Bridged Bicyclo Compounds; Cell Culture Techniques, Three Dimensional; Cell Line; Cell Survival; Down-Regulation; Humans; Keratinocytes; Nicotine; Signal Transduction; Smoking; Tight Junctions; Zonula Occludens-1 Protein | 2021 |