nicotine has been researched along with phenytoin in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (60.61) | 18.7374 |
| 1990's | 1 (3.03) | 18.2507 |
| 2000's | 8 (24.24) | 29.6817 |
| 2010's | 4 (12.12) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Caron, G; Ermondi, G | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Kostenbauder, HB; Lubawy, WC; McGovren, JP | 1 |
| Breckenridge, AM; Ohnhaus, EE; Park, BK | 1 |
| Hanson, HM; Ivester, CA; Morton, BR | 1 |
| Majewski, F | 1 |
| Santolucito, SA; Whitcomb, ER | 1 |
| Karmen, A; Lehrer, M | 1 |
| Spiehler, V | 1 |
| Barry, H; Sofia, RD; Solomon, TA | 1 |
| Giurgea, C; Mouravieff-Lesuisse, F | 2 |
| Oswald, I | 1 |
| Izquierdo, I; Nasello, AG | 1 |
| Oldendorf, WH | 1 |
| Vorherr, H | 1 |
| Lampe, KF | 1 |
| Beckett, AH | 1 |
| Dhasmana, KM; Dixit, KS; Kohli, RP; Saxena, RC | 1 |
| de Carolis, AS; Longo, VG | 1 |
| Tannhauser, M; Tannhauser, SL | 1 |
| Bickler, PE; Cardone, C; Szenohradszky, J; Yost, S | 1 |
7 review(s) available for nicotine and phenytoin
| Article | Year |
|---|---|
[Modification of the action of drugs by inhibition of their metabolism].
Topics: Antipyrine; Barbiturates; Drug Interactions; Enzyme Induction; Enzyme Repression; Ethanol; gamma-Glutamyltransferase; Glucaric Acid; Humans; Nicotine; Pharmaceutical Preparations; Pharmacology; Phenytoin; Rifampin | 1979 |
[On certain embryopathies induced by teratogenic agents (author's transl].
Topics: Abnormalities, Drug-Induced; Aminopterin; Busulfan; Chlorambucil; Cyclophosphamide; Ethanol; Germany, West; Heroin Dependence; Humans; Infant Mortality; Infant, Newborn; Lysergic Acid Diethylamide; Mercaptopurine; Nicotine; Phenytoin; Radiation Injuries; Teratogens; Thalidomide; Trimethadione; Warfarin | 1977 |
Drugs and sleep.
Topics: Aminobutyrates; Amphetamine; Animals; Antidepressive Agents; Barbiturates; Caffeine; Cats; Clinical Trials as Topic; Dihydroxyphenylalanine; Dreams; Drug Utilization; Ethanol; Hormones; Humans; Hydroxybutyrates; Hypnotics and Sedatives; Lysergic Acid Diethylamide; Methods; Monoamine Oxidase Inhibitors; Morphine; Nicotine; Parasympatholytics; Parasympathomimetics; Phenytoin; Rats; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tryptophan | 1968 |
Pharmacology of the brain: the hippocampus, learning and seizures.
Topics: Acetylcholine; Aminobutyrates; Amphetamine; Animals; Anura; Brain Chemistry; Dronabinol; Electric Stimulation; Evoked Potentials; Glutamates; Hippocampus; Learning; Nicotine; Norepinephrine; Osmolar Concentration; Phenytoin; Physostigmine; Potassium; Rats; RNA; Seizures; Serotonin; Stimulation, Chemical; Synaptic Transmission | 1972 |
Drug excretion in breast milk.
Topics: Anti-Bacterial Agents; Barbiturates; Biological Transport, Active; Breast; Breast Feeding; Caffeine; Chloramphenicol; Contraceptives, Oral; Coumarins; Female; Fluorine; Humans; Hydrogen-Ion Concentration; Infant; Infant, Newborn; Infant, Premature, Diseases; Jaundice, Neonatal; Lactation; Meprobamate; Milk, Human; Models, Biological; Morphine; Nicotine; Pesticides; Pharmaceutical Preparations; Phenytoin; Potassium Iodide; Pregnancy; Salicylates; Sulfonamides; Time Factors | 1974 |
Systemic plant poisoning in children.
Topics: Albumins; Alkaloids; Atropine; Atropine Derivatives; Basidiomycota; Charcoal; Child; Digitalis; Gastroenteritis; Humans; Mouth; Mushroom Poisoning; Nicotine; Phenytoin; Physostigmine; Plant Poisoning; Plants; Plants, Medicinal; Plants, Toxic; Poisons; Potassium Chloride; Renal Dialysis; Seizures; Toxins, Biological; Vomiting; Water-Electrolyte Balance | 1974 |
Effects of drug-drug and drug-food interaction on drug levels and performance in man.
Topics: Alcohol Drinking; Amphetamine; Animals; Animals, Laboratory; Behavior; Diet; Drug Interactions; Environment; Environmental Exposure; Environmental Health; Enzyme Induction; Enzyme Inhibitors; Enzymes; Ethanol; Humans; Hydrogen-Ion Concentration; Nicotine; Nutritional Physiological Phenomena; Phenobarbital; Phenytoin; Placenta; Psychopharmacology; Smoking | 1970 |
1 trial(s) available for nicotine and phenytoin
| Article | Year |
|---|---|
Drugs and sleep.
Topics: Aminobutyrates; Amphetamine; Animals; Antidepressive Agents; Barbiturates; Caffeine; Cats; Clinical Trials as Topic; Dihydroxyphenylalanine; Dreams; Drug Utilization; Ethanol; Hormones; Humans; Hydroxybutyrates; Hypnotics and Sedatives; Lysergic Acid Diethylamide; Methods; Monoamine Oxidase Inhibitors; Morphine; Nicotine; Parasympatholytics; Parasympathomimetics; Phenytoin; Rats; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tryptophan | 1968 |
26 other study(ies) available for nicotine and phenytoin
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
In vivo and in vitro alteration of nicotine metabolism by the major metabolite of phenytoin.
Topics: Animals; Cotinine; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Liver; Male; Models, Biological; Nicotine; Phenytoin; Rats; Time Factors | 1978 |
Nicotine self-administration in rats.
Topics: Amphetamine; Animals; Caffeine; Chlordiazepoxide; Chlorpromazine; Drug Interactions; Drug Tolerance; Ethanol; Humans; Male; Mecamylamine; Nicotine; Pentolinium Tartrate; Phenobarbital; Phenytoin; Rats; Reinforcement, Psychology; Self Administration; Substance-Related Disorders | 1979 |
The action of pesticides on conduction in the rat superior cervical ganglion.
Topics: Animals; Conditioning, Operant; Electric Stimulation; Ganglia, Spinal; Hydrocarbons, Chlorinated; In Vitro Techniques; Insecticides; Male; Nerve Tissue; Nicotine; Organophosphorus Compounds; Oxygen Consumption; Phenytoin; Rats | 1976 |
Chemical ionization mass spectrometry for rapid assay of drugs in serum.
Topics: Anticonvulsants; Barbiturates; Caffeine; Carbamazepine; Electrochemistry; Mass Spectrometry; Nicotine; Phenytoin; Primidone; Temperature; Time Factors | 1976 |
Drugs of abuse radioimmunoassay directory.
Topics: Amphetamine; Atropine; Barbiturates; Cannabis; Humans; Lysergic Acid Diethylamide; Mescaline; Morphine; Nicotine; Pentazocine; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Radioimmunoassay; Substance-Related Disorders | 1975 |
Anticonvulsant activity of delta9-tetrahydrocannabinol compared with three other drugs.
Topics: Animals; Anticonvulsants; Cannabis; Chlordiazepoxide; Dronabinol; Electroshock; Male; Mice; Nicotine; Pentylenetetrazole; Pharmaceutical Vehicles; Phenobarbital; Phenytoin; Seizures; Strychnine; Time Factors | 1976 |
Pharmacological studies on an elementary model of learning--the fixation of an experience at spinal level. I. Pharmacological reactivity of the spinal cord fixation time.
Topics: Animals; Antithyroid Agents; Azaguanine; Cerebellum; Cyanides; Hindlimb; Learning; Memory; Models, Psychological; Nicotine; Pemoline; Phenytoin; Posture; Procainamide; Psychophysiology; Pyrrolidinones; Rats; RNA; Spinal Cord; Strychnine; Time Factors; Transaminases | 1971 |
Brain uptake of metabolites and drugs following carotid arterial injections.
Topics: Acetates; Amino Acids; Animals; Antipyrine; Ascorbic Acid; Aspirin; Barbiturates; Blood-Brain Barrier; Brain; Caffeine; Chloroquine; Cyanides; Ethanol; Imipramine; Lactates; Mescaline; Morphine; Neurotransmitter Agents; Nicotine; Penicillin G; Pharmaceutical Preparations; Phenytoin; Procaine; Pyruvates; Rats | 1971 |
A simple method to measure central antinocotinic activity.
Topics: Animals; Atropine; Brain; Female; Infusions, Parenteral; Injections; Male; Methods; Mice; Nicotine; Phenobarbital; Phenytoin; Seizures | 1969 |
Influence of electro-convulsive shock on the fixation of an experience at spinal level.
Topics: Animals; Electroshock; Learning; Memory; Nicotine; Phenytoin; Posture; Procainamide; Propylamines; Rats; Time Factors | 1970 |
Studies on the anticonvulsant properties of some benzodiazepines. (Chlordiazepoxide, diazepam, oxazepam).
Topics: Action Potentials; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Electroencephalography; Female; Male; Morphine; Nicotine; Oxazepam; Phenobarbital; Phenytoin; Rabbits; Seizures; Strychnine | 1967 |
[Effects of combinations of diphenylhydantoin and amphetamine or nicotine in rats subjected to 2-way active avoidance conditioning].
Topics: Amphetamine; Animals; Avoidance Learning; Conditioning, Psychological; Drug Interactions; Female; Male; Nicotine; Phenytoin; Rats | 1981 |
Activation of brain acetylcholine receptors by neuromuscular blocking drugs. A possible mechanism of neurotoxicity.
Topics: Acetylcholine; Anesthesia, General; Animals; Atracurium; Brain; Calcium; Convulsants; Dose-Response Relationship, Drug; Enflurane; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Isoquinolines; Kainic Acid; Male; N-Methylaspartate; Neuromuscular Nondepolarizing Agents; Neurotoxins; Nicotine; Pancuronium; Phenytoin; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Time Factors; Tubocurarine; Vecuronium Bromide | 1994 |