Page last updated: 2024-08-26

nicotine and norcotinine

nicotine has been researched along with norcotinine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's4 (21.05)18.2507
2000's6 (31.58)29.6817
2010's7 (36.84)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Adam, BL; Gao, J; Terry, AV1
Foth, H; Kahl, GF; Walther, UI1
Altieri, I; Pacifici, R; Passa, AR; Pichini, S; Ricciarello, G; Rosa, M; Zuccaro, P1
Crooks, PA; Dwoskin, LP; Li, M1
Crooks, PA; Dwoskin, LP; Ghosheh, O; Li, WK1
BOWMAN, ER; McKENNIS, H; TURNBULL, LB; WADA, E1
Huestis, MA; Kim, I1
Benowitz, NL; Hukkanen, J; Jacob, P1
Gray, TR; Huestis, MA; Shakleya, DM1
Gray, TR; Huestis, MA; Magri, R; Shakleya, DM1
Huestis, MA; Shakleya, DM2
Huestis, MA; Scheidweiler, KB; Shakleya, DM1
Andrenyak, DM; Fleckenstein, AE; Nielsen, SM; Vieira-Brock, PL; Wilkins, DG1
Ande, A; Earla, R; Kumar, A; Kumar, S; McArthur, C1
Ansari, S; Buettner, A; Esposito, M; Gebel, S; Hoeng, J; Kogel, U; Leroy, P; Martin, F; Peitsch, MC; Schlage, WK; Vanscheeuwijck, P; Wyss, C; Xiang, Y1
Craig, EL; Cui, JZ; Miksys, S; Novalen, M; Tyndale, RF; Zhao, B1
Bernert, JT; Blount, BC; McGuffey, JE; Morrow, JC; Wang, L; Wei, B; Xia, B1
Boddu, SH; Bolla, PK; Cudjoe, E; Gionfriddo, E; Godage, NH; Neupane, R; Renukuntla, J1

Trials

1 trial(s) available for nicotine and norcotinine

ArticleYear
Effect of grapefruit juice on cytochrome P450 2A6 and nicotine renal clearance.
    Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:5

    Topics: Administration, Oral; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Beverages; Citrus paradisi; Cotinine; Cytochrome P-450 CYP2A6; Deuterium; Female; Ganglionic Stimulants; Glucuronides; Half-Life; Humans; Kidney; Liver; Male; Metabolic Clearance Rate; Middle Aged; Mixed Function Oxygenases; Nicotine

2006

Other Studies

18 other study(ies) available for nicotine and norcotinine

ArticleYear
Evaluation of nicotine and cotinine analogs as potential neuroprotective agents for Alzheimer's disease.
    Bioorganic & medicinal chemistry letters, 2014, Mar-15, Volume: 24, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Cells, Cultured; Cotinine; Humans; Neurons; Neuroprotective Agents; Nicotine; Peptide Fragments; Rats; Receptors, N-Methyl-D-Aspartate

2014
Increased hepatic nicotine elimination after phenobarbital induction in the conscious rat.
    Toxicology and applied pharmacology, 1990, Sep-15, Volume: 105, Issue:3

    Topics: Administration, Oral; Animals; Biological Availability; Carbon Radioisotopes; Cotinine; Injections, Intravenous; Kidney; Liver; Male; Nicotine; Phenobarbital; Pyrrolidines; Rats; Rats, Inbred Strains

1990
Determination of nicotine and four metabolites in the serum of smokers by high-performance liquid chromatography with ultraviolet detection.
    Journal of chromatography, 1993, Nov-24, Volume: 621, Issue:2

    Topics: Chromatography, High Pressure Liquid; Cotinine; Humans; Nicotine; Smoking

1993
Metabolites of nicotine in rat brain after peripheral nicotine administration. Cotinine, nornicotine, and norcotinine.
    Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:1

    Topics: Administration, Cutaneous; Animals; Brain; Brain Chemistry; Cotinine; Male; Nicotine; Rats; Rats, Sprague-Dawley; Time Factors

1997
Residence times and half-lives of nicotine metabolites in rat brain after acute peripheral administration of [2'-(14)C]nicotine.
    Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:12

    Topics: Animals; Brain; Carbon Radioisotopes; Cotinine; Gas Chromatography-Mass Spectrometry; Half-Life; Male; Nicotine; Rats; Rats, Sprague-Dawley; Time Factors

1999
Norcotinine (desmethylcotinine) as a urinary metabolite of nornicotine.
    Journal of medicinal and pharmaceutical chemistry, 1961, Jul-01, Volume: 4

    Topics: Cotinine; Humans; Nicotine

1961
A validated method for the determination of nicotine, cotinine, trans-3'-hydroxycotinine, and norcotinine in human plasma using solid-phase extraction and liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry.
    Journal of mass spectrometry : JMS, 2006, Volume: 41, Issue:6

    Topics: Atmospheric Pressure; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Cotinine; Humans; Nicotine; Sensitivity and Specificity; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization

2006
Quantification of nicotine, cotinine, trans-3'-hydroxycotinine, nornicotine and norcotinine in human meconium by liquid chromatography/tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Feb-15, Volume: 863, Issue:1

    Topics: Adult; Calibration; Chromatography, High Pressure Liquid; Cotinine; Female; Humans; Indicators and Reagents; Infant, Newborn; Mass Spectrometry; Meconium; Nicotine; Pregnancy; Quality Control; Reference Standards; Smoking; Tandem Mass Spectrometry

2008
Meconium nicotine and metabolites by liquid chromatography-tandem mass spectrometry: differentiation of passive and nonexposure and correlation with neonatal outcome measures.
    Clinical chemistry, 2008, Volume: 54, Issue:12

    Topics: Apgar Score; Biomarkers; Body Size; Chromatography, Liquid; Cotinine; Female; Gestational Age; Glucuronates; Humans; Hydrolysis; Infant, Newborn; Maternal Exposure; Maternal-Fetal Exchange; Meconium; Nicotine; Pregnancy; Smoking; Tandem Mass Spectrometry; Tobacco Smoke Pollution

2008
Simultaneous and sensitive measurement of nicotine, cotinine, trans-3'-hydroxycotinine and norcotinine in human plasma by liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Nov-01, Volume: 877, Issue:29

    Topics: Chromatography, Liquid; Cotinine; Humans; Nicotine; Sensitivity and Specificity; Tandem Mass Spectrometry

2009
Optimization and validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous quantification of nicotine, cotinine, trans-3'-hydroxycotinine and norcotinine in human oral fluid.
    Analytical and bioanalytical chemistry, 2009, Volume: 395, Issue:7

    Topics: Chromatography, Liquid; Cotinine; Gingival Crevicular Fluid; Humans; Mass Spectrometry; Nicotine; Reproducibility of Results; Sensitivity and Specificity

2009
Simultaneous quantification of nicotine, cotinine, trans-3'-hydroxycotinine, norcotinine and mecamylamine in human urine by liquid chromatography-tandem mass spectrometry.
    Clinica chimica acta; international journal of clinical chemistry, 2012, Jun-14, Volume: 413, Issue:11-12

    Topics: Calibration; Chromatography, Liquid; Cotinine; Humans; Mecamylamine; Nicotine; Sensitivity and Specificity; Smoking; Smoking Cessation; Tandem Mass Spectrometry

2012
Age-related differences in the disposition of nicotine and metabolites in rat brain and plasma.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2013, Volume: 15, Issue:11

    Topics: Administration, Cutaneous; Adolescent; Adult; Aging; Animals; Brain; Cotinine; Cyclic N-Oxides; Humans; Male; Nicotine; Rats; Rats, Sprague-Dawley

2013
Enhanced nicotine metabolism in HIV-1-positive smokers compared with HIV-negative smokers: simultaneous determination of nicotine and its four metabolites in their plasma using a simple and sensitive electrospray ionization liquid chromatography-tandem ma
    Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:2

    Topics: Adult; Biotransformation; Cotinine; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nicotine; Nicotinic Agonists; Reproducibility of Results; Smoking; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Up-Regulation

2014
A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared with conventional cigarettes.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 68

    Topics: Administration, Inhalation; Animals; Bronchoalveolar Lavage Fluid; Carboxyhemoglobin; Cell Differentiation; Chemokines; Cotinine; Cytokines; Endpoint Determination; Female; Inhalation Exposure; Lung; Male; Nicotiana; Nicotine; Organ Size; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Risk Assessment; Risk Factors; Tobacco Products; Transcriptome

2014
Nicotine pharmacokinetics in rats is altered as a function of age, impacting the interpretation of animal model data.
    Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:9

    Topics: Animals; Area Under Curve; Brain; Cotinine; Cyclic N-Oxides; Male; Models, Animal; Nicotine; Plasma; Rats; Rats, Wistar

2014
Validation of a LC-MS/MS method for quantifying urinary nicotine, six nicotine metabolites and the minor tobacco alkaloids--anatabine and anabasine--in smokers' urine.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Alkaloids; Anabasine; Chromatography, Liquid; Cotinine; Humans; Nicotine; Pyridines; Smoking; Tandem Mass Spectrometry

2014
Biocompatible SPME fibers for direct monitoring of nicotine and its metabolites at ultra trace concentration in rabbit plasma following the application of smoking cessation formulations.
    Journal of chromatography. A, 2020, Aug-30, Volume: 1626

    Topics: Anabasine; Animals; Chromatography, High Pressure Liquid; Cotinine; Isotope Labeling; Limit of Detection; Nicotine; Rabbits; Reference Standards; Reproducibility of Results; Smoking Cessation; Solid Phase Microextraction; Tandem Mass Spectrometry; Time Factors

2020