nicotine has been researched along with norcotinine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 7 (36.84) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Adam, BL; Gao, J; Terry, AV | 1 |
| Foth, H; Kahl, GF; Walther, UI | 1 |
| Altieri, I; Pacifici, R; Passa, AR; Pichini, S; Ricciarello, G; Rosa, M; Zuccaro, P | 1 |
| Crooks, PA; Dwoskin, LP; Li, M | 1 |
| Crooks, PA; Dwoskin, LP; Ghosheh, O; Li, WK | 1 |
| BOWMAN, ER; McKENNIS, H; TURNBULL, LB; WADA, E | 1 |
| Huestis, MA; Kim, I | 1 |
| Benowitz, NL; Hukkanen, J; Jacob, P | 1 |
| Gray, TR; Huestis, MA; Shakleya, DM | 1 |
| Gray, TR; Huestis, MA; Magri, R; Shakleya, DM | 1 |
| Huestis, MA; Shakleya, DM | 2 |
| Huestis, MA; Scheidweiler, KB; Shakleya, DM | 1 |
| Andrenyak, DM; Fleckenstein, AE; Nielsen, SM; Vieira-Brock, PL; Wilkins, DG | 1 |
| Ande, A; Earla, R; Kumar, A; Kumar, S; McArthur, C | 1 |
| Ansari, S; Buettner, A; Esposito, M; Gebel, S; Hoeng, J; Kogel, U; Leroy, P; Martin, F; Peitsch, MC; Schlage, WK; Vanscheeuwijck, P; Wyss, C; Xiang, Y | 1 |
| Craig, EL; Cui, JZ; Miksys, S; Novalen, M; Tyndale, RF; Zhao, B | 1 |
| Bernert, JT; Blount, BC; McGuffey, JE; Morrow, JC; Wang, L; Wei, B; Xia, B | 1 |
| Boddu, SH; Bolla, PK; Cudjoe, E; Gionfriddo, E; Godage, NH; Neupane, R; Renukuntla, J | 1 |
1 trial(s) available for nicotine and norcotinine
| Article | Year |
|---|---|
Effect of grapefruit juice on cytochrome P450 2A6 and nicotine renal clearance.
Topics: Administration, Oral; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Beverages; Citrus paradisi; Cotinine; Cytochrome P-450 CYP2A6; Deuterium; Female; Ganglionic Stimulants; Glucuronides; Half-Life; Humans; Kidney; Liver; Male; Metabolic Clearance Rate; Middle Aged; Mixed Function Oxygenases; Nicotine | 2006 |
18 other study(ies) available for nicotine and norcotinine
| Article | Year |
|---|---|
Evaluation of nicotine and cotinine analogs as potential neuroprotective agents for Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Cells, Cultured; Cotinine; Humans; Neurons; Neuroprotective Agents; Nicotine; Peptide Fragments; Rats; Receptors, N-Methyl-D-Aspartate | 2014 |
Increased hepatic nicotine elimination after phenobarbital induction in the conscious rat.
Topics: Administration, Oral; Animals; Biological Availability; Carbon Radioisotopes; Cotinine; Injections, Intravenous; Kidney; Liver; Male; Nicotine; Phenobarbital; Pyrrolidines; Rats; Rats, Inbred Strains | 1990 |
Determination of nicotine and four metabolites in the serum of smokers by high-performance liquid chromatography with ultraviolet detection.
Topics: Chromatography, High Pressure Liquid; Cotinine; Humans; Nicotine; Smoking | 1993 |
Metabolites of nicotine in rat brain after peripheral nicotine administration. Cotinine, nornicotine, and norcotinine.
Topics: Administration, Cutaneous; Animals; Brain; Brain Chemistry; Cotinine; Male; Nicotine; Rats; Rats, Sprague-Dawley; Time Factors | 1997 |
Residence times and half-lives of nicotine metabolites in rat brain after acute peripheral administration of [2'-(14)C]nicotine.
Topics: Animals; Brain; Carbon Radioisotopes; Cotinine; Gas Chromatography-Mass Spectrometry; Half-Life; Male; Nicotine; Rats; Rats, Sprague-Dawley; Time Factors | 1999 |
Norcotinine (desmethylcotinine) as a urinary metabolite of nornicotine.
Topics: Cotinine; Humans; Nicotine | 1961 |
A validated method for the determination of nicotine, cotinine, trans-3'-hydroxycotinine, and norcotinine in human plasma using solid-phase extraction and liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry.
Topics: Atmospheric Pressure; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Cotinine; Humans; Nicotine; Sensitivity and Specificity; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization | 2006 |
Quantification of nicotine, cotinine, trans-3'-hydroxycotinine, nornicotine and norcotinine in human meconium by liquid chromatography/tandem mass spectrometry.
Topics: Adult; Calibration; Chromatography, High Pressure Liquid; Cotinine; Female; Humans; Indicators and Reagents; Infant, Newborn; Mass Spectrometry; Meconium; Nicotine; Pregnancy; Quality Control; Reference Standards; Smoking; Tandem Mass Spectrometry | 2008 |
Meconium nicotine and metabolites by liquid chromatography-tandem mass spectrometry: differentiation of passive and nonexposure and correlation with neonatal outcome measures.
Topics: Apgar Score; Biomarkers; Body Size; Chromatography, Liquid; Cotinine; Female; Gestational Age; Glucuronates; Humans; Hydrolysis; Infant, Newborn; Maternal Exposure; Maternal-Fetal Exchange; Meconium; Nicotine; Pregnancy; Smoking; Tandem Mass Spectrometry; Tobacco Smoke Pollution | 2008 |
Simultaneous and sensitive measurement of nicotine, cotinine, trans-3'-hydroxycotinine and norcotinine in human plasma by liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, Liquid; Cotinine; Humans; Nicotine; Sensitivity and Specificity; Tandem Mass Spectrometry | 2009 |
Optimization and validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous quantification of nicotine, cotinine, trans-3'-hydroxycotinine and norcotinine in human oral fluid.
Topics: Chromatography, Liquid; Cotinine; Gingival Crevicular Fluid; Humans; Mass Spectrometry; Nicotine; Reproducibility of Results; Sensitivity and Specificity | 2009 |
Simultaneous quantification of nicotine, cotinine, trans-3'-hydroxycotinine, norcotinine and mecamylamine in human urine by liquid chromatography-tandem mass spectrometry.
Topics: Calibration; Chromatography, Liquid; Cotinine; Humans; Mecamylamine; Nicotine; Sensitivity and Specificity; Smoking; Smoking Cessation; Tandem Mass Spectrometry | 2012 |
Age-related differences in the disposition of nicotine and metabolites in rat brain and plasma.
Topics: Administration, Cutaneous; Adolescent; Adult; Aging; Animals; Brain; Cotinine; Cyclic N-Oxides; Humans; Male; Nicotine; Rats; Rats, Sprague-Dawley | 2013 |
Enhanced nicotine metabolism in HIV-1-positive smokers compared with HIV-negative smokers: simultaneous determination of nicotine and its four metabolites in their plasma using a simple and sensitive electrospray ionization liquid chromatography-tandem ma
Topics: Adult; Biotransformation; Cotinine; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nicotine; Nicotinic Agonists; Reproducibility of Results; Smoking; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Up-Regulation | 2014 |
A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared with conventional cigarettes.
Topics: Administration, Inhalation; Animals; Bronchoalveolar Lavage Fluid; Carboxyhemoglobin; Cell Differentiation; Chemokines; Cotinine; Cytokines; Endpoint Determination; Female; Inhalation Exposure; Lung; Male; Nicotiana; Nicotine; Organ Size; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Risk Assessment; Risk Factors; Tobacco Products; Transcriptome | 2014 |
Nicotine pharmacokinetics in rats is altered as a function of age, impacting the interpretation of animal model data.
Topics: Animals; Area Under Curve; Brain; Cotinine; Cyclic N-Oxides; Male; Models, Animal; Nicotine; Plasma; Rats; Rats, Wistar | 2014 |
Validation of a LC-MS/MS method for quantifying urinary nicotine, six nicotine metabolites and the minor tobacco alkaloids--anatabine and anabasine--in smokers' urine.
Topics: Alkaloids; Anabasine; Chromatography, Liquid; Cotinine; Humans; Nicotine; Pyridines; Smoking; Tandem Mass Spectrometry | 2014 |
Biocompatible SPME fibers for direct monitoring of nicotine and its metabolites at ultra trace concentration in rabbit plasma following the application of smoking cessation formulations.
Topics: Anabasine; Animals; Chromatography, High Pressure Liquid; Cotinine; Isotope Labeling; Limit of Detection; Nicotine; Rabbits; Reference Standards; Reproducibility of Results; Smoking Cessation; Solid Phase Microextraction; Tandem Mass Spectrometry; Time Factors | 2020 |