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nicotine and nicotine n-glucuronide

nicotine has been researched along with nicotine n-glucuronide in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (26.67)	18.2507
2000's	7 (46.67)	29.6817
2010's	3 (20.00)	24.3611
2020's	1 (6.67)	2.80

Authors

Authors	Studies
Andersson, G; Axéll, T; Curvall, M	1
Hawes, EM; Luo, H; Seaton, MJ; Vesell, ES	1
Andersson, G; Curvall, M; Vala, EK	1
Gorrod, JW; Tsai, MC	1
Bhatti, BS; Byrd, GD; Caldwell, WS; Crooks, PA; Ravard, A	1
Ghosheh, O; Hawes, EM	1
Bowers, RJ; Cole, SP; Deeley, RG; Létourneau, IJ	1
Bliss, RL; Carmella, SG; Heath, LA; Hecht, SS; Le, KA; McNiel, EA	1
Benowitz, NL; Krasnow, RE; Lessov-Schlaggar, CN; Mwenifumbo, JC; Swan, GE; Tyndale, RF; Zhou, Q	1
Feng, S; Kapur, S; Mendes, P; Muhammad, R; Newland, K; Roethig, HJ; Sarkar, M	1
Gray, TR; Huestis, MA; Magri, R; Shakleya, DM	1
Benowitz, NL; Dains, KM; Dempsey, D; Jacob, P; Yu, L	1
Grimm, SW; Guo, J; Zhou, D	1
Le Marchand, L; Murphy, SE; Park, SS; Patel, Y; Stram, DO; Thompson, EF; Wilkens, LR	1
Adams-Haduch, J; Chen, G; Khor, CC; Koh, WP; Lazarus, P; Nelson, HH; Perez-Paramo, YX; Thomas, CE; Wang, R; Watson, CJW; Yuan, JM	1

Trials

3 trial(s) available for nicotine and nicotine n-glucuronide

Article	Year
Identification of novel CYP2A61B variants: the CYP2A61B allele is associated with faster in vivo nicotine metabolism. Clinical pharmacology and therapeutics, 2008, Volume: 83, Issue:1 Topics: 3' Flanking Region; Aryl Hydrocarbon Hydroxylases; Base Sequence; Biotransformation; Cotinine; Cytochrome P-450 CYP2A6; Deuterium; Gene Frequency; Genetic Linkage; Genotype; Glucuronates; Humans; Infusions, Intravenous; Mixed Function Oxygenases; Molecular Sequence Data; Nicotine; Nicotinic Agonists; Phenotype; Polymorphism, Genetic; Sequence Alignment; Substrate Specificity	2008
Respiratory retention of nicotine and urinary excretion of nicotine and its five major metabolites in adult male smokers. Toxicology letters, 2007, Sep-10, Volume: 173, Issue:2 Topics: Adult; Biomarkers; Biotransformation; Breath Tests; Chromatography, Liquid; Cotinine; Glucuronates; Half-Life; Humans; Inhalation; Lung; Male; Models, Biological; Nicotine; Nicotinic Agonists; Smoking; Tandem Mass Spectrometry	2007
Nicotine N-glucuronidation relative to N-oxidation and C-oxidation and UGT2B10 genotype in five ethnic/racial groups. Carcinogenesis, 2014, Volume: 35, Issue:11 Topics: Adolescent; Adult; Ethnicity; Female; Genotype; Glucuronates; Glucuronosyltransferase; Hepatocytes; Humans; Male; Microsomes, Liver; Middle Aged; Neoplasms; Nicotine; Risk Factors; Smoking	2014

Other Studies

12 other study(ies) available for nicotine and nicotine n-glucuronide

Article	Year
Reduction in nicotine intake and oral mucosal changes among users of Swedish oral moist snuff after switching to a low-nicotine product. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1995, Volume: 24, Issue:6 Topics: Adult; Cotinine; Cyclic N-Oxides; Glucuronates; Humans; Mouth Diseases; Mouth Mucosa; Nicotine; Plants, Toxic; Saliva; Sweden; Time Factors; Tobacco, Smokeless	1995
Identification of radiolabeled metabolites of nicotine in rat bile. Synthesis of S-(-)-nicotine N-glucuronide and direct separation of nicotine-derived conjugates using high-performance liquid chromatography. Journal of chromatography, 1993, Nov-17, Volume: 621, Issue:1 Topics: Animals; Bile; Chromatography, High Pressure Liquid; Glucuronates; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Nicotine; Radiometry; Rats; Rats, Sprague-Dawley	1993
The influence of cigarette consumption and smoking machine yields of tar and nicotine on the nicotine uptake and oral mucosal lesions in smokers. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1997, Volume: 26, Issue:3 Topics: Adult; Cotinine; Cyclic N-Oxides; Environmental Exposure; Glucuronates; Humans; Leukoedema, Oral; Leukoplakia, Oral; Male; Middle Aged; Mouth Diseases; Mouth Mucosa; Nicotiana; Nicotine; Plants, Toxic; Prevalence; Smoking; Tars; Time Factors; Tongue, Hairy	1997
Evidence for the biosynthesis of A glucuronide conjugate of (S)-(-)-nicotine, but not (S)-(-)-cotinine or (+/-)-trans-3'-hydroxycotinine by marmoset hepatic microsomes. Drug metabolism and drug interactions, 1999, Volume: 15, Issue:4 Topics: Animals; Callithrix; Chromatography, High Pressure Liquid; Cotinine; Glucuronates; Guinea Pigs; In Vitro Techniques; Male; Microsomes, Liver; Nicotine; Octoxynol; Rabbits; Rats; Rats, Wistar; Uridine Diphosphate Glucuronic Acid	1999
Determination of nicotine N-1-glucuronide, a quaternary N-glucuronide conjugate, in human biological samples. Drug metabolism and drug interactions, 2000, Volume: 16, Issue:4 Topics: Adult; Biomarkers; Female; Glucuronates; Humans; Male; Mass Spectrometry; Middle Aged; Nicotine; Reproducibility of Results; Smoking	2000
N-glucuronidation of nicotine and cotinine in human: formation of cotinine glucuronide in liver microsomes and lack of catalysis by 10 examined UDP-glucuronosyltransferases. Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:9 Topics: Catalysis; Cotinine; Glucuronates; Glucuronides; Glucuronosyltransferase; Humans; In Vitro Techniques; Kinetics; Microsomes, Liver; Nicotine; Recombinant Proteins; Stereoisomerism	2002
Limited modulation of the transport activity of the human multidrug resistance proteins MRP1, MRP2 and MRP3 by nicotine glucuronide metabolites. Toxicology letters, 2005, May-16, Volume: 157, Issue:1 Topics: ATP-Binding Cassette Transporters; Cell Culture Techniques; Drug Resistance, Multiple; Ganglionic Stimulants; Glucuronates; Humans; Ion Transport; Kidney; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Nicotine; Pyridinium Compounds; Smoking	2005
Urinary biomarkers to assess exposure of cats to environmental tobacco smoke. American journal of veterinary research, 2007, Volume: 68, Issue:4 Topics: Animals; Biomarkers; Cats; Cotinine; Gas Chromatography-Mass Spectrometry; Glucuronates; Nicotine; Nitrosamines; Pyridines; Tobacco Smoke Pollution	2007
Meconium nicotine and metabolites by liquid chromatography-tandem mass spectrometry: differentiation of passive and nonexposure and correlation with neonatal outcome measures. Clinical chemistry, 2008, Volume: 54, Issue:12 Topics: Apgar Score; Biomarkers; Body Size; Chromatography, Liquid; Cotinine; Female; Gestational Age; Glucuronates; Humans; Hydrolysis; Infant, Newborn; Maternal Exposure; Maternal-Fetal Exchange; Meconium; Nicotine; Pregnancy; Smoking; Tandem Mass Spectrometry; Tobacco Smoke Pollution	2008
Estimation of nicotine dose after low-level exposure using plasma and urine nicotine metabolites. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:5 Topics: Adult; Biomarkers; Cotinine; Dose-Response Relationship, Drug; Female; Glucuronates; Humans; Male; Middle Aged; Nicotine; Smoking; Tobacco Smoke Pollution; Young Adult	2010
Liquid chromatography-tandem mass spectrometry method for measurement of nicotine N-glucuronide: a marker for human UGT2B10 inhibition. Journal of pharmaceutical and biomedical analysis, 2011, Jul-15, Volume: 55, Issue:5 Topics: Amitriptyline; Calibration; Chromatography, Liquid; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glucuronates; Glucuronosyltransferase; Humans; Imipramine; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Nicotine; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Temperature; Trifluoperazine	2011
Impact of Genetic Variants in the Nicotine Metabolism Pathway on Nicotine Metabolite Levels in Smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2023, 01-09, Volume: 32, Issue:1 Topics: Chromatography, Liquid; Cotinine; Cytochrome P-450 CYP2A6; Genotype; Glucuronosyltransferase; Humans; Nicotine; Smokers; Tandem Mass Spectrometry; Tobacco Use Disorder	2023