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nicotine and nicotine imine

nicotine has been researched along with nicotine imine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Obach, RS; Van Vunakis, H1
Gorrod, JW; Hibberd, AR1
Berkman, CE; Cashman, JR; Park, SB; Wrighton, SA1
Obach, RS1
Cooksy, A; Kovacic, P1
Murphy, SE; Retzlaff, C; von Weymarn, LB1
Bloom, AJ; Kharasch, ED; Wang, PF1

Other Studies

7 other study(ies) available for nicotine and nicotine imine

ArticleYear
Nicotinamide adenine dinucleotide (NAD)-dependent oxidation of nicotine-delta 1'(5')-iminium ion to cotinine by rabbit liver microsomes.
    Biochemical pharmacology, 1990, Jan-01, Volume: 39, Issue:1

    Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Arsenic; Arsenites; Cotinine; Microsomes, Liver; NAD; Nicotine; Oxidation-Reduction; Oxidoreductases; Pyrrolidinones; Rabbits; Vitamin K; Water

1990
Nicotine delta 1 "(5)' iminium ion: a reactive intermediate in nicotine metabolism.
    Advances in experimental medicine and biology, 1981, Volume: 136 Pt B

    Topics: Animals; Biotransformation; Cotinine; Cytosol; Glutathione; Guinea Pigs; Liver; Nicotine; Nitriles; Rabbits

1981
In vitro-in vivo correlations of human (S)-nicotine metabolism.
    Biochemical pharmacology, 1995, Aug-08, Volume: 50, Issue:4

    Topics: Adult; Aldehyde Oxidase; Aldehyde Oxidoreductases; Barbiturates; Biotransformation; Cotinine; Cyclic N-Oxides; Female; Humans; Kinetics; Male; Microsomes, Liver; Middle Aged; Nicotine; Stereoisomerism

1995
Potent inhibition of human liver aldehyde oxidase by raloxifene.
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:1

    Topics: Aldehyde Oxidase; Benzaldehydes; Enzyme Inhibitors; Humans; In Vitro Techniques; Kinetics; Liver; Nicotine; Oxidation-Reduction; Phthalazines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Xanthine Oxidase

2004
Iminium metabolite mechanism for nicotine toxicity and addiction: Oxidative stress and electron transfer.
    Medical hypotheses, 2005, Volume: 64, Issue:1

    Topics: Animals; Computer Simulation; Electron Transport; Humans; Models, Biological; Nicotine; Oxidative Stress; Reactive Oxygen Species; Tobacco Use Disorder

2005
CYP2A6- and CYP2A13-catalyzed metabolism of the nicotine Δ5'(1')iminium ion.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 343, Issue:2

    Topics: Aryl Hydrocarbon Hydroxylases; Catalysis; Chromatography, High Pressure Liquid; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; Enzyme Inhibitors; Humans; Kinetics; NADP; Nicotiana; Nicotine; Nicotinic Agonists; Oxidation-Reduction; Tritium

2012
Nicotine oxidation by genetic variants of CYP2B6 and in human brain microsomes.
    Pharmacology research & perspectives, 2019, Volume: 7, Issue:2

    Topics: Aged; Aged, 80 and over; Brain; Cytochrome P-450 CYP2B6; Female; Humans; Ketamine; Male; Methadone; Microsomes; Middle Aged; Nicotine; Oxidation-Reduction; Polymorphism, Single Nucleotide; Recombinant Proteins; Stereoisomerism; Tobacco Use Disorder

2019