Page last updated: 2024-08-26

nicotine and nicotine 1-n-oxide

nicotine has been researched along with nicotine 1-n-oxide in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (48.00)	18.7374
1990's	6 (24.00)	18.2507
2000's	3 (12.00)	29.6817
2010's	3 (12.00)	24.3611
2020's	1 (4.00)	2.80

Authors

Authors	Studies
Barfknecht, CF; Rosazza, JP; Sindelar, RD	1
Fujihara, S; Kurogochi, Y; Nakashima, T; Nakayama, H	1
Alexander, J; Armitage, AK; Hopkins, R; Ward, C	1
Crooks, PA; Nwosu, CG	1
Benowitz, NL; Jacob, P; Shulgin, AT; Yu, L	1
Hoffmann, D; LaVoie, EJ; Mu, B; Rivenson, A; Shigematsu, A	1
Norris, KJ; Petersen, DR; Thompson, JA	1
Axelrad, CM; Haley, NJ; LaVoie, EJ; Sepkovic, DW	1
Lekić, M; Nikolin, B; Rashid Mahmud, MA; Vísnjevac, O	1
Damiano, MD; Dvorchik, BH; Kyerematen, GA; Vesell, ES	1
Kainzbauer, J; Richter, O; Stehlik, G; Tausch, H	1
Caldwell, WS; de Bethizy, JD; Doolittle, DJ; Hayes, AW; Lee, CK; Winegar, R	1
Andersson, G; Axéll, T; Curvall, M	1
Berkman, CE; Cashman, JR; Park, SB; Wrighton, SA	1
Kitamura, S; Sugihara, K; Tatsumi, K	1
Andersson, G; Curvall, M; Vala, EK	1
Iwata, K; Kuroiwa, Y; Nakajima, M; Yamamoto, T; Yoshida, T	1
PAPADOPOULOS, NM	1
Benowitz, NL; Dempsey, D; Hukkanen, J; Jacob, P	1
Itoh, K; Nomura, A; Ochiai, Y; Sakurai, E; Tanaka, Y	1
Florek, E; Kulza, M; Loba, U; Piekoszewski, W; Wilimowska, J	1
Andrenyak, DM; Fleckenstein, AE; Nielsen, SM; Vieira-Brock, PL; Wilkins, DG	1
Craig, EL; Cui, JZ; Miksys, S; Novalen, M; Tyndale, RF; Zhao, B	1
Abu-Awwad, A; Arafat, T; Schmitz, OJ	1
Ito, S; Kitamura, N; Takanami, Y	1

Trials

1 trial(s) available for nicotine and nicotine 1-n-oxide

Article	Year
Evaluation of a low to middle tar/medium nicotine cigarette designed to maintain nicotine delivery to the smoker. Psychopharmacology, 1988, Volume: 96, Issue:4 Topics: Adult; Carbon Monoxide; Carboxyhemoglobin; Cyclic N-Oxides; Diet; Humans; Male; Middle Aged; Nicotine; Random Allocation; Reference Standards; Smoking	1988

Other Studies

24 other study(ies) available for nicotine and nicotine 1-n-oxide

Article	Year
N-demethylation of nicotine and reduction of nicotine-1'-N-oxide by Microsporum gypseum. Applied and environmental microbiology, 1979, Volume: 38, Issue:5 Topics: Chemical Phenomena; Chemistry; Cyclic N-Oxides; Fermentation; Fungi; Microsporum; Nicotine; Oxidation-Reduction; Species Specificity	1979
Formation of two major nicotine metabolites in livers of guinea pigs. Biochemical pharmacology, 1987, Dec-15, Volume: 36, Issue:24 Topics: Amines; Animals; Cotinine; Cyclic N-Oxides; Electron Transport; Flavin-Adenine Dinucleotide; Guinea Pigs; Immunologic Techniques; Liver; Methimazole; Metyrapone; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Nicotine; Oxidation-Reduction	1987
Species variation and stereoselectivity in the metabolism of nicotine enantiomers. Xenobiotica; the fate of foreign compounds in biological systems, 1988, Volume: 18, Issue:12 Topics: Animals; Cotinine; Cricetinae; Cyclic N-Oxides; Female; Guinea Pigs; Male; Mesocricetus; Nicotine; Rabbits; Rats; Rats, Inbred Strains; Sex Factors; Species Specificity; Stereoisomerism	1988
Determination of nicotine N-oxide by gas chromatography following thermal conversion to 2-methyl-6-(3-pyridyl)tetrahydro-1,2-oxazine. Analytical chemistry, 1986, Volume: 58, Issue:11 Topics: Chemical Phenomena; Chemistry; Chromatography, Gas; Cyclic N-Oxides; Humans; Nicotine; Oxazines	1986
Evaluation of the effects of cotinine and nicotine-N'-oxides on the development of tumors in rats initiated with N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide. Journal of the National Cancer Institute, 1985, Volume: 75, Issue:6 Topics: Animals; Body Weight; Carcinogens; Cocarcinogenesis; Cotinine; Cyclic N-Oxides; Digestive System Neoplasms; Drinking; Eating; FANFT; Male; Nicotine; Pyrrolidinones; Rats; Rats, Inbred F344; Smoking; Stereoisomerism; Urinary Bladder Neoplasms	1985
Isolation and analysis of N-oxide metabolites of tertiary amines: quantitation of nicotine-1'-N-oxide formation in mice. Journal of chromatography, 1985, Jun-14, Volume: 341, Issue:2 Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Liver; Male; Mice; Mice, Inbred DBA; Nicotine; Spectrophotometry, Ultraviolet; Stereoisomerism	1985
Thyroid hormone concentrations in rats after chronic nicotine metabolite administration. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1984, Volume: 177, Issue:3 Topics: Animals; Body Weight; Cotinine; Cyclic N-Oxides; Male; Nicotine; Pyrrolidinones; Rats; Rats, Inbred F344; Thyroid Hormones; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse	1984
Investigation of the content and ratio of cotinine and nicotine-1'-N-oxide in the urine of smokers. Arhiv za higijenu rada i toksikologiju, 1983, Volume: 34, Issue:3 Topics: Adult; Aged; Cotinine; Cyclic N-Oxides; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Nicotine; Pyrrolidinones; Smoking	1983
Smoking-induced changes in nicotine disposition: application of a new HPLC assay for nicotine and its metabolites. Clinical pharmacology and therapeutics, 1982, Volume: 32, Issue:6 Topics: Adult; Chromatography, High Pressure Liquid; Cotinine; Cyclic N-Oxides; Half-Life; Humans; Kinetics; Male; Nicotine; Smoking	1982
Improved method for routine determination of nicotine and its main metabolites in biological fluids. Journal of chromatography, 1982, Nov-12, Volume: 232, Issue:2 Topics: Chromatography, Gas; Cotinine; Cyclic N-Oxides; Humans; Nicotine	1982
The genotoxic potential of nicotine and its major metabolites. Mutation research, 1995, Volume: 344, Issue:3-4 Topics: Animals; CHO Cells; Cotinine; Cricetinae; Cyclic N-Oxides; Fluorenes; Mutagenicity Tests; Mutagens; Mutation; Nicotine; Salmonella typhimurium; Sister Chromatid Exchange	1995
Reduction in nicotine intake and oral mucosal changes among users of Swedish oral moist snuff after switching to a low-nicotine product. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1995, Volume: 24, Issue:6 Topics: Adult; Cotinine; Cyclic N-Oxides; Glucuronates; Humans; Mouth Diseases; Mouth Mucosa; Nicotine; Plants, Toxic; Saliva; Sweden; Time Factors; Tobacco, Smokeless	1995
In vitro-in vivo correlations of human (S)-nicotine metabolism. Biochemical pharmacology, 1995, Aug-08, Volume: 50, Issue:4 Topics: Adult; Aldehyde Oxidase; Aldehyde Oxidoreductases; Barbiturates; Biotransformation; Cotinine; Cyclic N-Oxides; Female; Humans; Kinetics; Male; Microsomes, Liver; Middle Aged; Nicotine; Stereoisomerism	1995
S-(-)-nicotine-1'-N-oxide reductase activity of rat liver aldehyde oxidase. Biochemistry and molecular biology international, 1996, Volume: 40, Issue:3 Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Benzaldehydes; Cyclic N-Oxides; Cytosol; Enzyme Inhibitors; Kinetics; Liver; Male; Nicotine; Pyrimidines; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Rats, Wistar	1996
The influence of cigarette consumption and smoking machine yields of tar and nicotine on the nicotine uptake and oral mucosal lesions in smokers. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1997, Volume: 26, Issue:3 Topics: Adult; Cotinine; Cyclic N-Oxides; Environmental Exposure; Glucuronates; Humans; Leukoedema, Oral; Leukoplakia, Oral; Male; Middle Aged; Mouth Diseases; Mouth Mucosa; Nicotiana; Nicotine; Plants, Toxic; Prevalence; Smoking; Tars; Time Factors; Tongue, Hairy	1997
Diastereospecific kinetics of nicotine N'-oxidation in rat liver microsomes. Xenobiotica; the fate of foreign compounds in biological systems, 1998, Volume: 28, Issue:2 Topics: Animals; Cyclic N-Oxides; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Enzyme Stability; Flavoproteins; Kinetics; Male; Microsomes, Liver; Molecular Conformation; Nicotine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Stereoisomerism; Thiourea	1998
NICOTINE-1'-OXIDE: A METABOLITE OF NICOTINE IN ANIMAL TISSUES. Archives of biochemistry and biophysics, 1964, Jul-20, Volume: 106 Topics: Animals; Carbon Isotopes; Chromatography; Cyclic N-Oxides; Infrared Rays; Liver; Metabolism; Nicotine; Rabbits; Research	1964
Effect of pregnancy on a measure of FMO3 activity. British journal of clinical pharmacology, 2005, Volume: 60, Issue:2 Topics: Antioxidants; Cyclic N-Oxides; Female; Humans; Hydrogen-Ion Concentration; Nicotine; Oxygenases; Pregnancy	2005
Metabolism of nicotine in rat lung microvascular endothelial cells. The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:3 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Chromatography, High Pressure Liquid; Cotinine; Cyclic N-Oxides; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Lung; Male; Membrane Proteins; Microcirculation; Nicotine; Oxygenases; Rats; Rats, Wistar; Steroid 16-alpha-Hydroxylase	2006
[Development of analytical method for determination nicotine metabolites in urine]. Przeglad lekarski, 2009, Volume: 66, Issue:10 Topics: Biomarkers; Chromatography, High Pressure Liquid; Cotinine; Cyclic N-Oxides; Environmental Exposure; Environmental Monitoring; Humans; Nicotine; Predictive Value of Tests	2009
Age-related differences in the disposition of nicotine and metabolites in rat brain and plasma. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2013, Volume: 15, Issue:11 Topics: Administration, Cutaneous; Adolescent; Adult; Aging; Animals; Brain; Cotinine; Cyclic N-Oxides; Humans; Male; Nicotine; Rats; Rats, Sprague-Dawley	2013
Nicotine pharmacokinetics in rats is altered as a function of age, impacting the interpretation of animal model data. Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:9 Topics: Animals; Area Under Curve; Brain; Cotinine; Cyclic N-Oxides; Male; Models, Animal; Nicotine; Plasma; Rats; Rats, Wistar	2014
Simultaneous determination of nicotine, cotinine, and nicotine N-oxide in human plasma, semen, and sperm by LC-Orbitrap MS. Analytical and bioanalytical chemistry, 2016, Volume: 408, Issue:23 Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Cotinine; Cyclic N-Oxides; Humans; Limit of Detection; Male; Nicotine; Semen; Spectrometry, Mass, Electrospray Ionization; Spermatozoa; Tobacco Smoking	2016
LC/MS analysis of three-dimensional model cells exposed to cigarette smoke or aerosol from a novel tobacco vapor product. The Journal of toxicological sciences, 2020, Volume: 45, Issue:12 Topics: Aerosols; Alkaloids; Bronchi; Carbolines; Cells, Cultured; Chromatography, Liquid; Culture Media; Cyclic N-Oxides; Epithelial Cells; Humans; Mass Spectrometry; Nicotiana; Nicotine; Respiratory Mucosa; Tobacco Products	2020