Page last updated: 2024-08-26

nicotine and nicardipine

nicotine has been researched along with nicardipine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's5 (26.32)18.2507
2000's7 (36.84)29.6817
2010's6 (31.58)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Jolivette, LJ; Ward, KW1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Baraldi, PG; Geppetti, P; Materazzi, S; Preti, D1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Baba, H; Okamura, T; Tanobe, Y; Toda, N1
Okamura, T; Toda, N1
Hori, K; Ito, S; Miyakawa, A; Mochizuki-Oda, N; Negishi, M; Ozaki, K1
Jia, CQ; Liu, TF; Sun, W; Wang, QS1
Adams, M; Boarder, MR; Marriott, D1
Browning, MD; Firestone, JA1
Aono, Y; Ariyoshi, H; Kawasaki, T; Monden, M; Sakon, M; Tsuji, Y; Ueda, A1

Reviews

1 review(s) available for nicotine and nicardipine

ArticleYear
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
    Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Peripheral Nervous System Diseases; Pulmonary Disease, Chronic Obstructive; Transient Receptor Potential Channels

2010

Other Studies

18 other study(ies) available for nicotine and nicardipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Mechanism of relaxation induced by K+ and nicotine in dog duodenal longitudinal muscle.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Adenosine Triphosphate; Animals; Apamin; Atropine; Bradykinin; Cations, Monovalent; Cyclic GMP; Dogs; Duodenum; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nicardipine; Nicotine; Ouabain; Oxyhemoglobins; Phentolamine; Potassium; Tetrodotoxin; Timolol

1992
Different susceptibility of vasodilator nerve, endothelium and smooth muscle functions to Ca++ antagonists in cerebral arteries.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:1

    Topics: Animals; Cadmium; Cerebral Arteries; Dogs; Drug Interactions; Electric Stimulation; Endothelium, Vascular; Female; Male; Muscle, Smooth, Vascular; Nerve Endings; Nicardipine; Nicotine; Nitric Oxide; Serotonin

1992
Characterization of prostaglandin E2-induced Ca2+ mobilization in single bovine adrenal chromaffin cells by digital image microscopy.
    Journal of neurochemistry, 1991, Volume: 56, Issue:2

    Topics: Adrenal Medulla; Animals; Calcium; Calcium Channel Blockers; Cattle; Chromaffin System; Dinoprostone; Fluorescent Dyes; Fura-2; Hexamethonium; Hexamethonium Compounds; Histamine; Kinetics; Lanthanum; Microscopy, Fluorescence; Nicardipine; Nicotine; Nicotinic Antagonists; Pertussis Toxin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1991
[Effects of nicardipine on automaticity of sinoatrial node in rabbit heart].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991, Volume: 12, Issue:5

    Topics: Action Potentials; Animals; Female; In Vitro Techniques; Isoproterenol; Male; Microelectrodes; Nicardipine; Nicotine; Rabbits; Sinoatrial Node

1991
Stimulus secretion coupling in cultured chromaffin cells. Dependency on external sodium and on dihydropyridine-sensitive calcium channels.
    Biochemical pharmacology, 1987, Jan-01, Volume: 36, Issue:1

    Topics: Acetylcholine; Adrenal Glands; Animals; Calcium; Calcium Channel Blockers; Cattle; Chromaffin Granules; Chromaffin System; Dose-Response Relationship, Drug; Ion Channels; Isomerism; Nicardipine; Nicotine; Sodium; Tetrodotoxin

1987
Calcium signalling in bovine adrenal chromaffin cells: additive effects of histamine and nicotine.
    Synapse (New York, N.Y.), 1994, Volume: 17, Issue:4

    Topics: Adrenal Glands; Animals; Calcium; Calcium-Transporting ATPases; Cattle; Cells, Cultured; Chromaffin System; Cytosol; Drug Synergism; Egtazic Acid; Histamine; Nicardipine; Nicotine; Signal Transduction; Terpenes; Thapsigargin

1994
Human umbilical vein endothelial cells (HUVECs) show Ca(2+) mobilization as well as Ca(2+) influx upon hypoxia.
    Journal of cellular biochemistry, 2000, Jun-06, Volume: 78, Issue:3

    Topics: Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Egtazic Acid; Endothelium, Vascular; Estrenes; Female; Humans; Hypoxia; Microscopy, Confocal; Nicardipine; Nicotine; Nifedipine; Pyrrolidinones; Type C Phospholipases; Umbilical Veins

2000