nicotine has been researched along with naltrexone in 86 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (5.81) | 18.7374 |
1990's | 17 (19.77) | 18.2507 |
2000's | 39 (45.35) | 29.6817 |
2010's | 21 (24.42) | 24.3611 |
2020's | 4 (4.65) | 2.80 |
Authors | Studies |
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Topliss, JG; Yoshida, F | 1 |
Jolivette, LJ; Ward, KW | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Maneckjee, R; Minna, JD | 1 |
Hamann, SR; Martin, WR | 1 |
Abood, LG; Hashmi, M; Lerner-Marmarosh, N; Manda, S | 1 |
Flores, CM; Hornby, PJ; Hulihan-Giblin, BA; Kellar, KJ; Lumpkin, MD | 1 |
Coen, KM; Corrigall, WA | 1 |
Davenport, KE; Houdi, AA; Van Loon, GR | 1 |
Bostwick, M; Martin, WR; Sloan, JW | 1 |
Flores, CM; Hulihan-Giblin, BA; Kellar, KJ | 1 |
Coen, KM; Corrigall, WA; Herling, S | 1 |
Chee, O; Keil, LC; Rosella-Dampman, LM; Summy-Long, JY | 1 |
Kamerling, SG; Martin, WR; Sloan, JW; Su, TP; Wettstein, JG | 1 |
Burden, HW; Davenport, A; Hodson, CA; Price, G | 1 |
Feyerabend, C; Russell, MA; Stapleton, JA; Sutherland, G | 1 |
Heidbreder, C; Shippenberg, TS; Shoaib, M | 1 |
Burden, HW; Davis, MC; Hodson, CA | 1 |
Caggiula, AR; Di Pirro, JM; Kristal, MB; Robinson-Vanderwerf, TM | 1 |
Dhatt, R; Tejwani, GA; Wewers, ME | 1 |
Bayer, BM; Mellon, RD | 1 |
Colby, SM; Gnys, M; Hutchison, KE; Monti, PM; Niaura, RS; Rohsenow, DJ; Sirota, AD; Swift, RM | 1 |
Behm, FM; Brauer, LH; Patel, P; Rose, JE; Westman, EC | 1 |
Cheng, CH; Naylor, RJ; Ngan, MP; Rudd, JA; Wai, MK | 1 |
Croghan, GA; Croghan, IT; Hurt, RD; Offord, KP; Wolter, TD; Wong, GY | 1 |
King, AC; Meyer, PJ | 1 |
Albuquerque, EX; Alkondon, M; Almeida, LE; Fawcett, WP; Pereira, EF; Randall, WR | 1 |
Hahn, B; Shoaib, M; Stolerman, IP | 1 |
Dermitzaki, E; Gravanis, A; Margioris, AN; Stournaras, C; Venihaki, M | 1 |
Benowitz, NL; Levine, JD; Miao, FJ | 1 |
Ahmadi, J; Ahmadi, M; Ahmadi, N; Ashkani, H | 1 |
Krishnan-Sarin, S; Meandzija, B; O'Malley, S | 1 |
Albuquerque, EX; Almeida, LE; Camara, AL; Maelicke, A; Pereira, EF | 1 |
Kosten, TR; Sofuoglu, M | 1 |
Hagan, JJ; Heidbreder, CA | 1 |
Jepson, C; Lerman, C; Lynch, KG; Patterson, F; Perkins, K; Rukstalis, M; Strasser, A | 1 |
Aso, E; Balerio, GN; Maldonado, R | 1 |
Byars, JA; Frost-Pineda, K; Gold, MS; Jacobs, WS | 1 |
Guaza, C; Llorente, R; Marco, EM; Moreno, E; Pérez-Alvarez, L; Viveros, MP | 1 |
O'Brien, CP | 1 |
Carstens, E; Carstens, MI; Cuellar, JM; Moore, JA; Pinkerton, KE; Simons, CT; Uyeminami, D | 1 |
Cooney, NL; McKee, SA; O'Malley, SS; Toll, BA | 1 |
Beilby, JJ; Doran, CM; Duszynski, KM; Mattick, RP | 1 |
Blakeslee, A; Cooney, JL; Cooney, NL; Dubin, JA; Jatlow, P; Krishnan-Sarin, S; Makuch, R; McKee, SA; Meandzija, B; O'Malley, SS; Romano-Dahlgard, D; Wu, R | 1 |
Berrettini, WH; Jepson, C; Lerman, C; Lynch, KG; O'Malley, S; Patterson, F; Perkins, K; Ray, R; Rukstalis, M; Strasser, A | 1 |
Diehl, A; Mann, K | 1 |
Hutchison, KE; Kaplan, GB; MacKinnon, SV; Monti, PM; Rohsenow, DJ; Sirota, AD; Swift, RM | 1 |
Baskett, JA; Kracke, GR; Lever, JR; Miller, DK; Rodvelt, KR; Will, MJ | 1 |
Jatlow, P; Martin, DJ; McKee, SA; O'Malley, SS; Toll, BA | 1 |
Campbell, VC; Taylor, RE; Tizabi, Y | 1 |
Katulak, NA; O'Malley, S; Toll, BA; Williams-Piehota, P | 1 |
Blendy, J; Jepson, C; Lerman, C; Patterson, F; Perkins, K; Ray, R; Rukstalis, M; Strasser, AA; Wileyto, P | 1 |
Fisher, DJ; Knott, VJ | 1 |
Ahtee, L; Korpi, ER; Piltonen, M; Tuominen, RK; Vihavainen, T | 1 |
Epstein, A; King, A; Munisamy, G; Walsh, Z | 1 |
Cooney, JL; Cooney, NL; McKee, SA; O'Malley, SS; Toll, BA | 1 |
al'Absi, M; Hatsukami, D; Westra, R; Wittmers, LE | 1 |
Booth, S; Caggiula, AR; Donny, EC; Gharib, M; Liu, X; Palmatier, MI; Sved, AF | 1 |
McKee, SA | 1 |
Berrendero, F; Maldonado, R; Martín-García, E; Robledo, P; Trigo, JM | 1 |
Ismayilova, N; Shoaib, M | 1 |
Brown, ML; Kellar, KJ; Levin, ED; Li, TK; Lumeng, L; McDowell, BE; Paige, MA; Petro, A; Rezvani, AH; Rose, JE; Slade, S; Wells, C; Xiao, Y | 1 |
Jatlow, P; Makuch, R; Meandzija, B; O'Malley, SS; Toll, BA; White, M; Wu, R | 1 |
Amin, Z; Czarkowski, KA; Epperson, CN; Jatlow, P; Mazure, CM; O'Malley, SS; Toll, B; Wu, R | 1 |
Carroll, FI; Damaj, MI; Jackson, KJ; McLaughlin, JP | 1 |
Natividad, LA; O'Dell, LE; Orfila, JE; Tejeda, HA; Torres, OV | 1 |
Chavkin, C; Chavkin, NW; Gustin, RM; Hagan, CE; Lemos, JC; Messinger, DI; Neumaier, JF; Schattauer, SS; Schindler, AG; Shankar, H; Smith, JS | 1 |
Gillman, AG; Kosobud, AE; Leffel, JK; Timberlake, W | 1 |
Coen, K; Funk, D; Grella, SL; Lê, AD; Li, Z | 1 |
Coen, K; Funk, D; Lê, AD; Lo, S | 1 |
Jatlow, PI; Mayne, ST; O'Malley, SS; Wu, R | 1 |
Fisher, DC; Fletcher, PJ; Guy, EG; Higgins, GA | 1 |
Goutier, W; Kloeze, M; McCreary, AC | 1 |
Bruchas, MR; Carlezon, WA; Hourguettes, NJ; Nygard, SK; Sobczak, GG | 1 |
D'Souza, MS; Norman, H; Ward, M | 1 |
Anton, RF; Book, SW; Hoffman, M; Latham, PK; Randall, PK; Schacht, JP; Voronin, KE | 1 |
Bardo, MT; Bell, RL; Crooks, PA; Dwoskin, LP; Maggio, SE; Nixon, K; Prendergast, MA; Saunders, MA; Zheng, G | 1 |
Hauser, SR; Knight, CP; McBride, WJ; Pratt, LA; Rodd, ZA; Waeiss, RA | 1 |
Bardo, MT; Chandler, CM; Maggio, SE; Nixon, K; Peng, H | 1 |
Amstislavskaya, TG; de Abreu, MS; Demin, KA; Galstyan, DS; Giacomini, ACVV; Kalueff, AV; Kolesnikova, TO; Petersen, EV; Strekalova, T; Zabegalov, KN | 1 |
al'Absi, M; Allen, S; Anker, JJ; Nakajima, M; Raatz, S | 1 |
Bower, M; de Wit, H; Hoots, JK; Nunez, C; Schepers, ST; Wardle, MC | 1 |
7 review(s) available for nicotine and naltrexone
Article | Year |
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Pharmacologic management of relapse prevention in addictive disorders.
Topics: Administration, Cutaneous; Administration, Oral; Alcohol Deterrents; Alcoholism; Behavior, Addictive; Disulfiram; Humans; Naltrexone; Narcotics; Nicotine; Smoking Cessation; Smoking Prevention; Substance-Related Disorders | 2004 |
Novel pharmacotherapeutic approaches for the treatment of drug addiction and craving.
Topics: Alcoholism; Clinical Trials as Topic; Cocaine-Related Disorders; Humans; Naltrexone; Narcotic Antagonists; Nicotine; Opioid-Related Disorders; Structure-Activity Relationship; Substance-Related Disorders; Tobacco Use Disorder | 2005 |
Anticraving medications for relapse prevention: a possible new class of psychoactive medications.
Topics: Alcoholism; Behavior, Addictive; Bupropion; Cocaine-Related Disorders; Disulfiram; Humans; Naltrexone; Nicotine; Psychotherapy; Psychotropic Drugs; Secondary Prevention; Substance-Related Disorders; Tobacco Use Disorder | 2005 |
[Pharmacological relapse prevention in alcohol and tobacco dependence].
Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Clinical Trials as Topic; Combined Modality Therapy; Disulfiram; Humans; Naltrexone; Nicotine; Psychotherapy; Secondary Prevention; Smoking Cessation; Substance Withdrawal Syndrome; Taurine; Tobacco Use Disorder | 2007 |
Developing human laboratory models of smoking lapse behavior for medication screening.
Topics: Alcohol Drinking; Arousal; Bupropion; Cues; Drug Evaluation, Preclinical; Humans; Models, Psychological; Motivation; Naltrexone; Nicotine; Psychotropic Drugs; Secondary Prevention; Smoking; Smoking Cessation; Smoking Prevention; Social Environment; Social Facilitation; Tobacco Use Disorder | 2009 |
Neurobiological mechanisms involved in nicotine dependence and reward: participation of the endogenous opioid system.
Topics: Animals; Behavior, Addictive; Humans; Motivation; Naltrexone; Neurotransmitter Agents; Nicotine; Opioid Peptides; Receptors, Nicotinic; Reinforcement, Psychology; Reward; Smoking Cessation; Tobacco Use Disorder | 2010 |
Unconventional anxiety pharmacology in zebrafish: Drugs beyond traditional anxiogenic and anxiolytic spectra.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Aspirin; Behavior, Animal; Disease Models, Animal; Humans; Lysergic Acid Diethylamide; Motor Activity; Naloxone; Naltrexone; Nicotine; Zebrafish | 2021 |
22 trial(s) available for nicotine and naltrexone
Article | Year |
---|---|
Naltrexone, smoking behaviour and cigarette withdrawal.
Topics: Adult; Affect; Behavior; Female; Humans; Male; Naltrexone; Nicotine; Placebo Effect; Reinforcement, Psychology; Smoking; Substance Withdrawal Syndrome; Time Factors | 1995 |
Naltrexone administration affects ad libitum smoking behavior.
Topics: Adult; Affect; Double-Blind Method; Female; Humans; Male; Naltrexone; Narcotic Antagonists; Nicotine; Reinforcement, Psychology; Smoking; Substance Withdrawal Syndrome | 1998 |
Effects of naltrexone with nicotine replacement on smoking cue reactivity: preliminary results.
Topics: Adult; Analysis of Variance; Cues; Female; Humans; Male; Naltrexone; Narcotic Antagonists; Nicotine; Smoking; Substance Withdrawal Syndrome | 1999 |
Naltrexone blockade of nicotine effects in cigarette smokers.
Topics: Adult; Affect; Analysis of Variance; Double-Blind Method; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Nicotine; Placebos; Smoking; Substance Withdrawal Syndrome; Surveys and Questionnaires | 1999 |
A randomized trial of naltrexone for smoking cessation.
Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Aged; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Smoking Cessation | 1999 |
Naltrexone alteration of acute smoking response in nicotine-dependent subjects.
Topics: Adult; Affect; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Nicotine; Smoking; Smoking Cessation; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2000 |
Twenty-four week maintenance treatment of cigarette smoking with nicotine gum, clonidine and naltrexone.
Topics: Adult; Antihypertensive Agents; Chewing Gum; Clonidine; Double-Blind Method; Humans; Iran; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Nicotine; Prospective Studies; Smoking; Smoking Cessation; Smoking Prevention; Time Factors | 2003 |
Naltrexone and nicotine patch smoking cessation: a preliminary study.
Topics: Administration, Cutaneous; Adult; Female; Ganglionic Stimulants; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Nicotine; Placebos; Smoking Cessation; Tobacco Use Disorder; Treatment Outcome | 2003 |
Naltrexone reduces the relative reinforcing value of nicotine in a cigarette smoking choice paradigm.
Topics: Adolescent; Adult; Aged; Bupropion; Choice Behavior; Double-Blind Method; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Nicotine; Reinforcement, Psychology; Smoking Cessation; Tobacco Use Disorder | 2005 |
Naltrexone augments the effects of nicotine replacement therapy in female smokers.
Topics: Administration, Cutaneous; Administration, Topical; Adult; Combined Modality Therapy; Double-Blind Method; Female; Humans; Naltrexone; Narcotic Antagonists; Nicotine; Psychotherapy; Smoking; Smoking Cessation; Smoking Prevention; Tobacco Use Disorder | 2005 |
Do daily interactive voice response reports of smoking behavior correspond with retrospective reports?
Topics: Data Collection; Double-Blind Method; Female; Humans; Male; Mental Recall; Middle Aged; Naltrexone; Narcotic Antagonists; Nicotine; Patient Compliance; Self Disclosure; Sensitivity and Specificity; Smoking; Smoking Cessation; Telephone; Time Factors | 2005 |
A controlled trial of naltrexone augmentation of nicotine replacement therapy for smoking cessation.
Topics: Administration, Cutaneous; Administration, Oral; Ambulatory Care; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Linear Models; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Smoking Cessation; Substance Withdrawal Syndrome; Surveys and Questionnaires; Treatment Outcome; Weight Gain | 2006 |
Association of OPRM1 A118G variant with the relative reinforcing value of nicotine.
Topics: Adaptation, Psychological; Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Nicotine; Polymorphism, Genetic; Receptors, Opioid, mu; Reinforcement, Psychology; Risk Factors; Sex Factors; Smoking; Smoking Cessation; Substance Withdrawal Syndrome | 2006 |
High-dose transdermal nicotine and naltrexone: effects on nicotine withdrawal, urges, smoking, and effects of smoking.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Blood Pressure; Breath Tests; Capsules; Carbon Monoxide; Demography; Disruptive, Impulse Control, and Conduct Disorders; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Smoking; Substance Withdrawal Syndrome; Surveys and Questionnaires; Tablets | 2007 |
Validation of a scale for the assessment of food cravings among smokers.
Topics: Administration, Cutaneous; Appetite; Dietary Fats; Dietary Sucrose; Female; Food Preferences; Humans; Male; Naltrexone; Nicotine; Placebos; Reproducibility of Results; Smoking; Smoking Cessation; Surveys and Questionnaires; Taste; Weight Gain | 2008 |
Naltrexone alteration of the nicotine-induced EEG and mood activation response in tobacco-deprived cigarette smokers.
Topics: Adult; Affect; Analysis of Variance; Blood Pressure; Double-Blind Method; Electroencephalography; Female; Heart Rate; Humans; Male; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Substance Withdrawal Syndrome; Surveys and Questionnaires | 2007 |
The impact of depressive symptoms on the efficacy of naltrexone in smoking cessation.
Topics: Administration, Cutaneous; Adult; Combined Modality Therapy; Counseling; Depression; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Nicotine; Personality Inventory; Smoking Cessation; Treatment Outcome | 2008 |
Blunted opiate modulation of hypothalamic-pituitary-adrenocortical activity in men and women who smoke.
Topics: Adrenocorticotropic Hormone; Arousal; Double-Blind Method; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Naltrexone; Narcotic Antagonists; Nicotine; Opioid Peptides; Pain Measurement; Pain Threshold; Pituitary-Adrenal System; Saliva; Sex Factors; Thermosensing; Tobacco Use Disorder; Young Adult | 2008 |
Low-dose naltrexone augmentation of nicotine replacement for smoking cessation with reduced weight gain: a randomized trial.
Topics: Administration, Cutaneous; Adult; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naltrexone; Nicotine; Prospective Studies; Smoking; Smoking Cessation; Weight Gain | 2010 |
Exploring the impact of gender and reproductive status on outcomes in a randomized clinical trial of naltrexone augmentation of nicotine patch.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Body Weight; Female; Humans; Interviews as Topic; Male; Medication Adherence; Menstrual Cycle; Middle Aged; Naltrexone; Narcotic Antagonists; Nicotine; Sex Characteristics; Smoking Cessation; Treatment Outcome; Young Adult | 2010 |
Smoking cessation is followed by increases in serum bilirubin, an endogenous antioxidant associated with lower risk of lung cancer and cardiovascular disease.
Topics: Administration, Cutaneous; Adult; Antioxidants; Bilirubin; Cardiovascular Diseases; Counseling; Double-Blind Method; Female; Humans; Lung Neoplasms; Male; Middle Aged; Naltrexone; Nicotine; Risk Factors; Smoking; Smoking Cessation; Tobacco Use Cessation Devices; Treatment Outcome | 2014 |
Nicotine-Use/Smoking Is Associated with the Efficacy of Naltrexone in the Treatment of Alcohol Dependence.
Topics: Adolescent; Adult; Aged; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Biomarkers; Double-Blind Method; Drug Interactions; Female; Humans; Male; Middle Aged; Naltrexone; Nicotine; Sialoglycoproteins; Smoking; Transferrin; Treatment Outcome; Young Adult | 2018 |
57 other study(ies) available for nicotine and naltrexone
Article | Year |
---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Nonconventional opioid binding sites mediate growth inhibitory effects of methadone on human lung cancer cells.
Topics: Binding Sites; Calcium; Cell Death; Cell Division; Cell Membrane; Cyclic AMP; Cycloheximide; Dactinomycin; Growth Inhibitors; Humans; Methadone; Morphine; Naltrexone; Nicotine; Pertussis Toxin; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Stereoisomerism; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
Opioid and nicotinic analgesic and hyperalgesic loci in the rat brain stem.
Topics: Analgesia; Animals; Brain Stem; Dose-Response Relationship, Drug; Ethylketocyclazocine; Female; Mecamylamine; Microinjections; Naltrexone; Nicotine; Rats; Rats, Inbred Strains; Receptors, Opioid | 1992 |
Opioid receptor antagonist affinity ligands: 6 beta-bromoacetamido-6-desoxynaltrexone and 6 beta-thioglycolamido-6-desoxynaltrexone.
Topics: Affinity Labels; Analgesia; Animals; Brain; Cattle; Cell Membrane; Hydrogen-Ion Concentration; Kinetics; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Nicotine; Quinuclidinyl Benzilate; Receptors, Opioid | 1992 |
Partial characterization of a neurotransmitter pathway regulating the in vivo release of prolactin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bromocriptine; Haloperidol; Male; Mecamylamine; Methysergide; Morphine; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Nicotine; Nicotinic Antagonists; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Nicotinic; Receptors, Opioid; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1992 |
Opiate antagonists reduce cocaine but not nicotine self-administration.
Topics: Animals; Cocaine; Conditioning, Operant; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nicotine; Rats; Reinforcement Schedule; Self Administration | 1991 |
Nicotine protects against mu-opioid receptor antagonism by beta-funaltrexamine: evidence for nicotine-induced release of endogenous opioids in brain.
Topics: Analgesia; Animals; Brain; Endorphins; Injections, Intraventricular; Male; Morphine; Naltrexone; Nicotine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1990 |
Mechanisms involved in the respiratory depressant actions of nicotine in anesthetized rats.
Topics: Anesthesia; Animals; Female; Hexamethonium; Hexamethonium Compounds; Mecamylamine; Naltrexone; Nicotine; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Receptors, Opioid; Respiration; Urethane | 1989 |
Naltrexone blocks nicotine-induced prolactin release.
Topics: Animals; Catheterization; Male; Mecamylamine; Morphine; Naltrexone; Nicotine; Prolactin; Rats; Rats, Inbred Strains | 1989 |
Evidence for opioid mechanisms in the behavioral effects of nicotine.
Topics: Animals; Behavior, Animal; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Heroin; Male; Mecamylamine; Naltrexone; Nicotine; Rats; Rats, Inbred Strains; Receptors, Opioid | 1988 |
Naltrexone effects on plasma vasopressin concentration elevated and lowered by various stimuli.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Hematocrit; Male; Naloxone; Naltrexone; Nicotine; Rats; Rats, Inbred Strains; Sodium; Stress, Physiological; Water-Electrolyte Balance | 1983 |
Interaction between nicotine and endogenous opioid mechanisms in the unanesthetized dog.
Topics: Animals; Body Temperature; Brain; Dogs; Endorphins; Enkephalin, Methionine; Female; Heart Rate; Injections, Intraventricular; Naltrexone; Nicotine; Pupil; Reflex; Respiration; Skin Physiological Phenomena | 1982 |
Naltrexone treatment attenuates the inhibitory effect of nicotine treatment on serum LH in rats.
Topics: Adrenalectomy; Animals; Dexamethasone; Drug Therapy, Combination; Luteinizing Hormone; Male; Naltrexone; Nicotine; Rats; Rats, Sprague-Dawley | 1993 |
Differential role of delta-opioid receptors in the development and expression of behavioral sensitization to cocaine.
Topics: Animals; Behavior, Animal; Cocaine; Male; Motor Activity; Naltrexone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta | 1996 |
Effect of prior nicotine treatment on drug induced changes in serum LH concentrations in rats.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dopamine Antagonists; Drug Administration Schedule; Drug Interactions; Gonadotropin-Releasing Hormone; Haloperidol; Luteinizing Hormone; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Stimulation, Chemical | 1997 |
The analgesia-enhancing component of ingested amniotic fluid does not affect nicotine-induced antinociception in naltrexone-treated rats.
Topics: Amniotic Fluid; Analgesia; Analgesics; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Female; Morphine; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Pain Measurement; Pregnancy; Rats; Reaction Time | 1997 |
The effects of morphine, nicotine and epibatidine on lymphocyte activity and hypothalamic-pituitary-adrenal axis responses.
Topics: Adjuvants, Immunologic; Analgesics, Opioid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Chlorisondamine; Dose-Response Relationship, Drug; Drug Interactions; Hypothalamo-Hypophyseal System; Lymphocyte Activation; Male; Morphine; Naltrexone; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pituitary-Adrenal System; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Opioid; T-Lymphocytes | 1999 |
Modulation of emesis by fentanyl and opioid receptor antagonists in Suncus murinus (house musk shrew).
Topics: Animals; Antiemetics; Female; Fentanyl; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nicotine; Receptors, Opioid; Shrews; Vomiting | 1999 |
The opioid antagonist naltrexone inhibits activity and alters expression of alpha7 and alpha4beta2 nicotinic receptors in hippocampal neurons: implications for smoking cessation programs.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cells, Cultured; Electrophysiology; Female; Hippocampus; In Vitro Techniques; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Pregnancy; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Smoking Cessation; Up-Regulation | 2000 |
Kappa-opioid receptor modulation of nicotine-induced behaviour.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Behavior, Animal; Benzeneacetamides; Benzofurans; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Motor Activity; Naltrexone; Nicotine; Nicotinic Agonists; Pyrrolidines; Rats; Receptors, Opioid, kappa | 2000 |
Opioids suppress basal and nicotine-induced catecholamine secretion via a stabilizing effect on actin filaments.
Topics: Actins; Animals; Benzeneacetamides; Cytochalasin B; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Humans; Naltrexone; Narcotics; Nicotine; Norepinephrine; PC12 Cells; Pyrrolidines; Rats | 2001 |
Endogenous opioids suppress activation of nociceptors by sub-nanomolar nicotine.
Topics: Adrenal Medulla; Analysis of Variance; Animals; Animals, Newborn; Bradykinin; Capsaicin; Dose-Response Relationship, Drug; Hexamethonium; Inflammation; Knee Joint; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Nicotine; Nociceptors; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Opioid; Sciatic Nerve; Time Factors | 2001 |
Sensitivity of neuronal nicotinic acetylcholine receptors to the opiate antagonists naltrexone and naloxone: receptor blockade and up-regulation.
Topics: Cell Line; Gene Expression; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Nicotine; Patch-Clamp Techniques; Receptors, Nicotinic; Sensitivity and Specificity; Smoking Cessation; Structure-Activity Relationship; Time Factors; Up-Regulation | 2004 |
Involvement of the opioid system in the effects induced by nicotine on anxiety-like behaviour in mice.
Topics: Analysis of Variance; Animals; Anxiety Disorders; Behavior, Animal; Dose-Response Relationship, Drug; Drug Antagonism; Drug Synergism; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Maze Learning; Mecamylamine; Mice; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Opioid | 2005 |
The kappa-opioid receptor is involved in the stimulating effect of nicotine on adrenocortical activity but not in nicotine induced anxiety.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Corticosterone; Drug Interactions; Endocrine System; Male; Maze Learning; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Opioid, kappa | 2005 |
Nicotinic receptor involvement in antinociception induced by exposure to cigarette smoke.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Male; Mecamylamine; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nociceptors; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Opioid, mu; Smoking | 2005 |
Use of pharmacotherapies for the management of addictive behaviours in Australian clinical practice.
Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Australia; Bupropion; Dopamine Uptake Inhibitors; Female; Health Care Surveys; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Nicotine; Substance-Related Disorders; Taurine; Tobacco Use Disorder | 2006 |
Lobeline, a potential pharmacotherapy for drug addiction, binds to mu opioid receptors and diminishes the effects of opioid receptor agonists.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; Brain; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guinea Pigs; In Vitro Techniques; Lobeline; Mecamylamine; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Nicotine; Oocytes; Radioligand Assay; Receptors, Opioid; Receptors, Opioid, mu; Xenopus laevis | 2007 |
Factor structure and validity of the Medication Adherence Questionnaire (MAQ) with cigarette smokers trying to quit.
Topics: Adult; Attitude to Health; Factor Analysis, Statistical; Female; Humans; Male; Naltrexone; Narcotic Antagonists; Nicotine; Patient Compliance; Psychometrics; Reproducibility of Results; Smoking; Smoking Cessation; Substance Withdrawal Syndrome; Surveys and Questionnaires; Tobacco Use Disorder | 2007 |
Effects of selective opioid receptor antagonists on alcohol-induced and nicotine-induced antinociception.
Topics: Analgesics; Animals; Central Nervous System Depressants; Ethanol; Hot Temperature; Male; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Pain Measurement; Peptide Fragments; Peptides; Rats; Rats, Wistar; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin | 2007 |
CREB1 haplotypes and the relative reinforcing value of nicotine.
Topics: Association Learning; Case-Control Studies; Choice Behavior; Cyclic AMP Response Element-Binding Protein; Double-Blind Method; Haplotypes; Humans; Linkage Disequilibrium; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Polymorphism, Single Nucleotide; Receptors, Opioid, mu; Regression Analysis; Reward; Smoking; Tobacco Use Disorder | 2007 |
Morphine-nicotine interaction in conditioned place preference in mice after chronic nicotine exposure.
Topics: Analgesics, Opioid; Animals; Autoradiography; Conditioning, Operant; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guanosine 5'-O-(3-Thiotriphosphate); Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Receptors, Opioid, mu | 2008 |
Correspondence of Interactive Voice Response (IVR) reports of nicotine withdrawal, craving, and negative mood with questionnaire ratings.
Topics: Adult; Comorbidity; Depression; Female; Humans; Irritable Mood; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Nicotine; Self Disclosure; Self-Assessment; Smoking Cessation; Substance Withdrawal Syndrome; Surveys and Questionnaires | 2008 |
Naltrexone attenuation of conditioned but not primary reinforcement of nicotine in rats.
Topics: Animals; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Extinction, Psychological; Food; Male; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration | 2009 |
Alteration of intravenous nicotine self-administration by opioid receptor agonist and antagonists in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dose-Response Relationship, Drug; Feeding Behavior; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nicotine; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Self Administration; Tobacco Use Disorder | 2010 |
Effects of sazetidine-A, a selective alpha4beta2 nicotinic acetylcholine receptor desensitizing agent on alcohol and nicotine self-administration in selectively bred alcohol-preferring (P) rats.
Topics: Animals; Azetidines; Dose-Response Relationship, Drug; Drug Administration Schedule; Ethanol; Male; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Pyridines; Rats; Receptors, Nicotinic; Reward; Saccharin; Self Administration | 2010 |
Effects of the kappa opioid receptor antagonist, norbinaltorphimine, on stress and drug-induced reinstatement of nicotine-conditioned place preference in mice.
Topics: Animals; Conditioning, Psychological; Disease Models, Animal; Extinction, Psychological; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Nicotine; Receptors, Opioid, kappa; Recurrence; Risk Factors; Self Administration; Smoking; Stress, Psychological | 2013 |
Dysregulation of kappa-opioid receptor systems by chronic nicotine modulate the nicotine withdrawal syndrome in an age-dependent manner.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Aging; Animals; Behavior, Animal; Dopamine; Dose-Response Relationship, Drug; Male; Naltrexone; Nicotine; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Opioid, kappa; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2012 |
Stress produces aversion and potentiates cocaine reward by releasing endogenous dynorphins in the ventral striatum to locally stimulate serotonin reuptake.
Topics: Animals; Avoidance Learning; Brain; Cocaine; Corpus Striatum; Dopamine; Dynorphins; G-Protein-Coupled Receptor Kinase 3; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microinjections; Naltrexone; Narcotic Antagonists; Nicotine; Nucleus Accumbens; p38 Mitogen-Activated Protein Kinases; Raphe Nuclei; Receptors, Opioid, kappa; Reward; Serotonin; Serotonin Plasma Membrane Transport Proteins; Signal Transduction; Stress, Psychological; Substance Withdrawal Syndrome; Synaptosomes | 2012 |
Behavioral characteristics and pharmacological manipulations of a nicotine-entrainable circadian oscillator.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Benzoxazoles; Circadian Rhythm; Feeding Behavior; Female; Fructose; Light; Motor Activity; Naltrexone; Naphthyridines; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Oscillometry; Rats; Rats, Sprague-Dawley; Time Factors; Topiramate; Urea | 2013 |
Role of the kappa-opioid receptor system in stress-induced reinstatement of nicotine seeking in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-2 Receptor Antagonists; Analgesics, Non-Narcotic; Animals; Conditioning, Operant; Drug Administration Schedule; Drug Interactions; Extinction, Psychological; Male; Naltrexone; Nicotine; Nicotinic Agonists; Rats; Rats, Long-Evans; Receptors, Opioid, kappa; Self Administration; Stress, Psychological; Tobacco Use Disorder; Yohimbine | 2014 |
Operant self-administration of alcohol and nicotine in a preclinical model of co-abuse.
Topics: Alcoholism; Animals; Behavior, Addictive; Conditioning, Operant; Disease Models, Animal; Ethanol; Male; Naltrexone; Nicotine; Rats; Rats, Long-Evans; Self Administration; Smoking | 2014 |
Examination of the effects of varenicline, bupropion, lorcaserin, or naltrexone on responding for conditioned reinforcement in nicotine-exposed rats.
Topics: Animals; Benzazepines; Bupropion; Cholinergic Agents; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Male; Naltrexone; Narcotic Antagonists; Nicotine; Quinoxalines; Rats; Rats, Long-Evans; Reinforcement, Psychology; Varenicline | 2014 |
Nicotine-induced locomotor sensitization: pharmacological analyses with candidate smoking cessation aids.
Topics: Acamprosate; Analysis of Variance; Animals; Antidiuretic Hormone Receptor Antagonists; Bupropion; Dose-Response Relationship, Drug; Fructose; Indoles; Male; Motor Activity; Naltrexone; Nicotine; Nicotinic Agonists; Pyrrolidines; Rats, Wistar; Taurine; Tobacco Use Cessation Devices; Topiramate | 2016 |
Stress-Induced Reinstatement of Nicotine Preference Requires Dynorphin/Kappa Opioid Activity in the Basolateral Amygdala.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Basolateral Nuclear Complex; Clozapine; Conditioning, Operant; Drug-Seeking Behavior; Dynorphins; Extinction, Psychological; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Proto-Oncogene Proteins c-fos; Receptors, Opioid, kappa; Reinforcement, Psychology; Yohimbine | 2016 |
Effects of pharmacological manipulation of the kappa opioid receptors on the aversive effects of nicotine.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Avoidance Learning; Conditioning, Operant; Male; Naltrexone; Narcotic Antagonists; Nicotine; Rats; Rats, Wistar; Receptors, Opioid, kappa; Taste | 2018 |
An improved model of ethanol and nicotine co-use in female P rats: Effects of naltrexone, varenicline, and the selective nicotinic α6β2* antagonist r-bPiDI.
Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Disease Models, Animal; Ethanol; Female; Naltrexone; Nicotine; Nicotinic Antagonists; Picolines; Pyridinium Compounds; Rats; Self Administration; Smoking Cessation Agents; Tobacco Use Disorder; Treatment Outcome; Varenicline | 2018 |
Therapeutic challenges for concurrent ethanol and nicotine consumption: naltrexone and varenicline fail to alter simultaneous ethanol and nicotine intake by female alcohol-preferring (P) rats.
Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Ethanol; Female; Injections, Subcutaneous; Naltrexone; Nicotine; Random Allocation; Rats; Self Administration; Smoking Cessation Agents; Tobacco Use Disorder; Varenicline | 2019 |
Effects of ethanol, naltrexone, nicotine and varenicline in an ethanol and nicotine co-use model in Sprague-Dawley rats.
Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Ethanol; Female; Male; Naltrexone; Nicotine; Rats; Rats, Sprague-Dawley; Self Administration; Smoking Cessation Agents; Tobacco Use Disorder; Varenicline | 2020 |
Tobacco withdrawal increases junk food intake: The role of the endogenous opioid system.
Topics: Analgesics, Opioid; Eating; Humans; Naltrexone; Nicotiana; Nicotine; Substance Withdrawal Syndrome | 2021 |
Pharmacological investigations of effort-based decision-making in humans: Naltrexone and nicotine.
Topics: Adult; Cholinergic Agents; Decision Making; Dopamine; Humans; Motivation; Naltrexone; Nicotine; Pilot Projects; Reward | 2022 |