Page last updated: 2024-08-26

nicotine and naloxone

nicotine has been researched along with naloxone in 112 studies

Research

Studies (112)

Timeframe	Studies, this research(%)	All Research%
pre-1990	31 (27.68)	18.7374
1990's	33 (29.46)	18.2507
2000's	33 (29.46)	29.6817
2010's	13 (11.61)	24.3611
2020's	2 (1.79)	2.80

Authors

Authors	Studies
Campbell, BG; Kimes, AS; London, ED; Scheffel, U; Wilson, AA	1
Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Fujiwara, M; Muramatsu, I; Nakashima, M; Shikimi, T	1
Dingledine, R; Goldstein, A	1
Abood, LG; Hashmi, M; Lerner-Marmarosh, N; Manda, S	1
Huston-Lyons, D; Kornetsky, C	1
Abood, LG; Hashmi, M; Saraswati, M	1
Antonelli, T; Beani, L; Bianchi, C; Ferraro, L; Morari, M; Nordberg, A; Spalluto, P; Tanganelli, S	1
Iwamoto, ET	1
Coen, KM; Corrigall, WA	1
Cruz, SL; Salazar, LA; Villarreal, JE	1
Baker, M; Endoh, K; Leung, FW	1
Cooley, JE; Fowler, SC; Lombardo, TW; Moss, RA; Sult, S; Villarosa, GA	1
Cherubini, E; Morita, K; North, RA	1
Del Rio, J; Molinero, MT	1
Acquas, E; Carboni, E; Di Chiara, G; Leone, P	1
Livett, BG; Marley, PD	1
Johnson, M; Lightman, SL; Seckl, JR; Shakespear, C	1
Arai, H; Hosoda, K; Itoh, H; Morii, N; Mukoyama, M; Nakao, K; Saito, Y; Shirakami, G; Sugawara, A; Yamada, T	1
Pappas, GD; Pollard, HB; Sagen, J	1
Culver, PJ; Rattan, S	1
Chiodera, P; Coiro, V; d'Amato, L; Davoli, C; Delsignore, R; Gnudi, A; Volpi, R	1
Pappas, GD; Perlow, MJ; Sagen, J	2
Aubert, JF; Brunner, HR; Burnier, M; Nussberger, J; Waeber, B	1
Ibayashi, H; Kato, K; Nawata, H; Yanase, T	1
Denlinger, C; Hartman, RD; Palm, D; Rosella-Dampman, LM; Summy-Long, JY	1
Artalejo, AR; García, AG; Montiel, C; Sánchez-García, P	1
Brase, DA; Loh, HH; Tseng, LF; Way, EL	1
Fosbraey, P; Johnson, ES	1
Lajtha, A; Reith, ME; Sershen, H	1
Brien, J; Jhamandas, K; Marien, M	1
Ishii, T; Shimo, Y	1
Costa, E; Guidotti, A; Karoum, F; Kumakura, K	1
Graudenz, M; Izquierdo, I	1
Martin, WR; Wu, KM	1
Haertzen, CA; Henningfield, JE; Hickey, JE; Jasinski, DR; Johnson, RE; Kumor, K	1
Chee, O; Keil, LC; Rosella-Dampman, LM; Summy-Long, JY	1
Forsling, M; Langdon, N; Lightman, S; Todd, K	1
Jenouri, G; Sackner, MA; Tobin, MJ	1
Badawy, AA; Evans, M; Punjani, NF	2
Diana, JN; Dowell, RT; Houdi, AA	1
Carter, VA; Cunningham, JS; Lake, JR; Malin, DH; Wilson, OB	1
Eyl, C; Hakan, RL; Hart, C	1
Friderichs, E; Reimann, W; Reinartz, S; Selve, N	1
Aceto, MD; Bowman, ER; Ji, Z; Scates, SM	1
Bocchi, R; Caffarri, G; Capretti, L; Chiodera, P; Coiro, V; Marcato, A; Rossi, G; Volpi, R	1
Abood, LG; Hashmi, M; Lerner-Marmarosh, N; Saraswati, M	1
Gravanis, A; Margioris, AN; Venihaki, M	1
Kinney, HC; Panigrahy, A; Reddy, SC; White, WF	1
Carter, VA; Cunningham, JS; Lake, JR; Malin, DH; Payne, MC; Short, PE; Wilson, OB	1
Farzin, D; Zarrindast, MR	1
Heidbreder, C; Lefevour, A; Shippenberg, TS	1
Bodor, N; Prokai, L; Prokai-Tatrai, K	1
Mucha, RF	1
Benowitz, NL; Heller, PH; Levine, JD; Miao, FJ	1
Burden, HW; Davis, MC; Hodson, CA	1
Assmann, S; Kinney, HC; Panigrahy, A; Rava, LA; Sleeper, LA; White, WF	1
Adams, ML; Cicero, TJ	1
Di Chiara, G; Tanda, G	1
Pan, J; Shieh, K	1
Funabashi, T; Kawaguchi, M; Kimura, F; Sano, A; Shinohara, K	1
Cheng, CH; Naylor, RJ; Ngan, MP; Rudd, JA; Wai, MK	1
Koneczny, B; Kozłowska, H; Malinowska, B; Schlicker, E	1
Bortone, L; Carboni, E; Di Chiara, G; Giua, C	1
Koob, GF; Markou, A; Stinus, L; Watkins, SS	1
George, TP; Roth, RH; Verrico, CD; Xu, L	1
Ise, Y; Nagase, H; Narita, M; Suzuki, T	1
Barghi-Lashkari, S; Shafizadeh, M; Zarrindast, MR	1
Changeux, JP; Damaj, MI; Epping-Jordan, MP; Marubio, LM; Merlo-Pich, E; Salmon, AM	1
Benowitz, NL; Levine, JD; Miao, FJ	1
Ceña, V; González-García, C; Izaguirre, V; Rosário, LM; Tomé, AR	1
Javid, FA; Naylor, RJ	1
Klein, LC	1
Childs, E; Hahn, B; Morley, A; Stolerman, IP	1
Faraji, N; Ghoshouni, H; Rostami, P; Sahraei, H; Zarrindast, MR	1
Andrews, PL; Paton, JF; Smith, JE	1
Benowitz, N; Green, P; Levine, JD; Miao, FJ	1
Araki, H; Futagami, K; Gomita, Y; Jin, C; Kawakami, KY; Kawasaki, H; Kitamura, Y; Nagata, M; Shibata, K; Suemaru, K	1
Dhawan, K; Kumar, S; Sharma, A	1
Albuquerque, EX; Almeida, LE; Camara, AL; Maelicke, A; Pereira, EF	1
Bevins, RA; Palmatier, MI; Peterson, JL; Wilkinson, JL	1
Aso, E; Balerio, GN; Berrendero, F; Maldonado, R; Murtra, P	1
Blendy, JA; Cleck, JN; Kuo, YC; Walters, CL	1
DeNoble, VJ; Mele, PC	1
Araki, H; Gomita, Y; Jin, C; Kawasaki, H; Kawasaki, Y; Motoshima, S; Suemaru, K	1
Biggio, G; Brundu, A; Concas, A; Marra, C; Porcu, P; Sogliano, C	1
Campbell, VC; Taylor, RE; Tizabi, Y	1
Mohajeri, S; Zarrindast, MR	1
Alizadeh, AM; Haghparast, A; Khani, A; Motamedi, F; Naderi, N	1
Kiguchi, N; Kishioka, S; Maeda, T; Ozaki, M; Tsuruga, M; Yamamoto, A; Yamamoto, C	1
Baarendse, PJ; Trezza, V; Vanderschuren, LJ	1
Ismayilova, N; Shoaib, M	1
Lecca, S; Luchicchi, A; Melis, M; Muntoni, AL; Pistis, M	1
Kiguchi, N; Kishioka, S; Kobayashi, Y; Maeda, T; Ozaki, M; Saika, F; Ueno, K; Wakida, N; Yamamoto, C	1
Aso, E; Balerio, GN; Maldonado, R; Moutinho, LM; Varani, AP	1
Kiguchi, N; Kishioka, S; Kobayashi, Y; Saika, F	1
Gruca, P; Lason-Tyburkiewicz, M; Litwa, E; Papp, M; Willner, P	1
Kiguchi, N; Kishioka, S; Kobayashi, Y; Saika, F; Yamamoto, C	1
Candiotti, KA; Gitlin, M; Rodriguez-Blanco, YF; Sevilla, A; Su, C; Weller, R; Wu, J; Yang, J; Zhang, Y; Zheng, C	1
Amstislavskaya, TG; de Abreu, MS; Demin, KA; Galstyan, DS; Giacomini, ACVV; Kalueff, AV; Kolesnikova, TO; Petersen, EV; Strekalova, T; Zabegalov, KN	1

Reviews

4 review(s) available for nicotine and naloxone

Article	Year
The role of receptor binding in drug discovery. Journal of natural products, 1993, Volume: 56, Issue:4 Topics: Animals; Drug Design; Humans; Receptors, Drug	1993
Nicotine effects and the endogenous opioid system. Journal of pharmacological sciences, 2014, Volume: 125, Issue:2 Topics: alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; Enkephalin, Methionine; Humans; Hypothalamo-Hypophyseal System; Naloxone; Narcotic Antagonists; Nicotine; Opioid Peptides; Pituitary-Adrenal System; Spinal Cord; Substance Withdrawal Syndrome; Tobacco Use Disorder	2014
[Development of physical dependence on nicotine and endogenous opioid system--participation of α7 nicotinic acetylcholine receptor]. Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence, 2014, Volume: 49, Issue:5 Topics: alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; Brain; Dynorphins; Endorphins; Enkephalins; Humans; Hypothalamo-Hypophyseal System; Mice; Naloxone; Narcotic Antagonists; Nicotine; Nociception; Opioid Peptides; Pituitary-Adrenal System; Tobacco Use Disorder	2014
Unconventional anxiety pharmacology in zebrafish: Drugs beyond traditional anxiogenic and anxiolytic spectra. Pharmacology, biochemistry, and behavior, 2021, Volume: 207 Topics: Animals; Anti-Anxiety Agents; Anxiety; Aspirin; Behavior, Animal; Disease Models, Animal; Humans; Lysergic Acid Diethylamide; Motor Activity; Naloxone; Naltrexone; Nicotine; Zebrafish	2021

Trials

1 trial(s) available for nicotine and naloxone

Article	Year
Naloxone increases the nicotine-stimulated rise of vasopressin secretion in man. Clinical endocrinology, 1982, Volume: 16, Issue:4 Topics: Adult; Arginine Vasopressin; Female; Humans; Male; Naloxone; Nicotine; Osmolar Concentration; Plasma; Urine	1982

Other Studies

107 other study(ies) available for nicotine and naloxone

Article	Year
Radiosynthesis, cerebral distribution, and binding of [125I]-1-(p-iodophenyl)-3-(1-adamantyl)guanidine, a ligand for sigma binding sites. Journal of medicinal chemistry, 1992, Dec-11, Volume: 35, Issue:25 Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Guanidines; Guinea Pigs; Iodobenzenes; Male; Mice; Receptors, sigma; Tissue Distribution	1992
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Effects of loperamide on the guinea pig taenia coli. European journal of pharmacology, 1979, Apr-15, Volume: 55, Issue:2 Topics: Acetylcholine; Animals; Colon; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Loperamide; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Nicotine; Piperidines; Serotonin	1979
Single neuron studies of opiate action in the guinea pig myenteric plexus. Life sciences, 1975, Jul-01, Volume: 17, Issue:1 Topics: Animals; Axons; Dextrorphan; Electrodes; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Levorphanol; Male; Models, Biological; Morphine; Myenteric Plexus; Naloxone; Narcotics; Neural Conduction; Neural Inhibition; Nicotine; Serotonin; Serotonin Antagonists	1975
Opioid receptor antagonist affinity ligands: 6 beta-bromoacetamido-6-desoxynaltrexone and 6 beta-thioglycolamido-6-desoxynaltrexone. Neurochemical research, 1992, Volume: 17, Issue:12 Topics: Affinity Labels; Analgesia; Animals; Brain; Cattle; Cell Membrane; Hydrogen-Ion Concentration; Kinetics; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Nicotine; Quinuclidinyl Benzilate; Receptors, Opioid	1992
Effects of nicotine on the threshold for rewarding brain stimulation in rats. Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:4 Topics: Animals; Brain; Electric Stimulation; Male; Mecamylamine; Naloxone; Nicotine; Rats; Rats, Inbred F344; Reward; Self Stimulation	1992
4-Bromoacetamidoprocaine: an affinity ligand for brain muscarinic and nicotinic cholinergic receptors. Neurochemical research, 1992, Volume: 17, Issue:3 Topics: Animals; Behavior, Animal; Brain; Carbachol; Chloromercuribenzoates; Hyperkinesis; Ligands; Mercaptoethanol; Molecular Structure; Naloxone; Nicotine; p-Chloromercuribenzoic Acid; Procaine; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Receptors, Nicotinic; Seizures	1992
Effect of acute and subchronic nicotine treatment on cortical efflux of [3H]-D-aspartate and endogenous GABA in freely moving guinea-pigs. British journal of pharmacology, 1991, Volume: 104, Issue:1 Topics: Acetylcholine; Animals; Aspartic Acid; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Guinea Pigs; Injections, Intraventricular; Injections, Subcutaneous; Male; Mecamylamine; Methysergide; Naloxone; Nicotine; Receptors, GABA-A; Receptors, Nicotinic	1991
Characterization of the antinociception induced by nicotine in the pedunculopontine tegmental nucleus and the nucleus raphe magnus. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:1 Topics: Analgesia; Animals; Dioxolanes; Glutamates; Glutamic Acid; Hemicholinium 3; Male; Mecamylamine; Medulla Oblongata; Naloxone; Nicotine; Procainamide; Raphe Nuclei; Rats; Rats, Inbred Strains; Reflex	1991
Opiate antagonists reduce cocaine but not nicotine self-administration. Psychopharmacology, 1991, Volume: 104, Issue:2 Topics: Animals; Cocaine; Conditioning, Operant; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nicotine; Rats; Reinforcement Schedule; Self Administration	1991
A methodological basis for improving the reliability of measurements of opiate abstinence responses in the guinea-pig ileum made dependent in vitro. Journal of pharmacological methods, 1991, Volume: 25, Issue:4 Topics: Animals; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Naloxone; Narcotics; Nicotine; Receptors, Nicotinic; Reference Standards; Substance Withdrawal Syndrome	1991
Mechanism of intragastric nicotine protection against ethanol-induced gastric injury. Digestive diseases and sciences, 1991, Volume: 36, Issue:1 Topics: Animals; Capsaicin; Ethanol; Gastric Acid; Gastric Juice; Gastric Mucosa; Male; Naloxone; Nicotine; Rats; Rats, Inbred Strains; Regional Blood Flow	1991
Effect of pCPA on nicotine-induced analgesia. Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:2 Topics: Analgesia; Animals; Drug Interactions; Fenclonine; Male; Mecamylamine; Naloxone; Nicotine; Pain; Rats; Rats, Inbred Strains; Sensory Thresholds	1990
Opioid inhibition of synaptic transmission in the guinea-pig myenteric plexus. British journal of pharmacology, 1985, Volume: 85, Issue:4 Topics: Acetylcholine; Action Potentials; Animals; Barium; Electric Conductivity; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Guinea Pigs; Ileum; Morphine; Myenteric Plexus; Naloxone; Nicotine; Potassium; Substance P; Synaptic Transmission	1985
Substance P, nicotinic acetylcholine receptors and antinociception in the rat. Neuropharmacology, 1987, Volume: 26, Issue:12 Topics: Analgesics; Animals; Hexamethonium Compounds; Injections, Intraventricular; Male; Mecamylamine; Naloxone; Neurokinin A; Neurokinin B; Neuropeptides; Nicotine; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Cholinergic; Substance P	1987
SCH 23390 blocks drug-conditioned place-preference and place-aversion: anhedonia (lack of reward) or apathy (lack of motivation) after dopamine-receptor blockade? Psychopharmacology, 1989, Volume: 99, Issue:2 Topics: Animals; Antipsychotic Agents; Avoidance Learning; Benzazepines; Choice Behavior; Diazepam; Injections, Subcutaneous; Male; Morphine; Motivation; Naloxone; Nicotine; Phencyclidine; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Dopamine	1989
Effects of opioid compounds on desensitization of the nicotinic response of isolated bovine adrenal chromaffin cells. Biochemical pharmacology, 1987, Sep-15, Volume: 36, Issue:18 Topics: Adrenal Medulla; Animals; Calcium; Cattle; Cells, Cultured; Chromaffin System; Diprenorphine; Drug Tolerance; Dynorphins; Endorphins; Enkephalin, Methionine; Epinephrine; Etorphine; Morphine; Naloxone; Nicotine; Norepinephrine; Peptide Fragments; Potassium	1987
Endogenous opioids inhibit oxytocin release during nicotine-stimulated secretion of vasopressin in man. Clinical endocrinology, 1988, Volume: 28, Issue:5 Topics: Adult; Arginine Vasopressin; Endorphins; Humans; Male; Naloxone; Nicotine; Oxytocin; Smoking	1988
Opioid modulation of vasopressin secretion in conscious rats. Clinical and experimental hypertension. Part A, Theory and practice, 1988, Volume: 10 Suppl 1 Topics: Animals; Blood Pressure; Carbachol; Endorphins; Enkephalins; Heart Rate; Male; Naloxone; Nicotine; Protein Precursors; Rats; Rats, Inbred Strains; Vasopressins	1988
Analgesia induced by isolated bovine chromaffin cells implanted in rat spinal cord. Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:19 Topics: Analgesia; Animals; Chromaffin System; Naloxone; Nicotine; Pain; Rats; Spinal Cord; Subarachnoid Space	1986
Influence of loperamide on the internal anal sphincter in the opossum. Gastroenterology, 1987, Volume: 93, Issue:1 Topics: Anal Canal; Animals; Drug Interactions; Electric Stimulation; Female; Isoproterenol; Loperamide; Male; Naloxone; Nicotine; Opossums; Piperidines; Pressure; Rectum; Spinal Nerve Roots; Verapamil	1987
Naloxone decreases the inhibiting effect of ethanol on the release of arginine-vasopressin induced by cigarette smoking in man. Metabolism: clinical and experimental, 1987, Volume: 36, Issue:8 Topics: Adult; Arginine Vasopressin; Ethanol; Female; Humans; Male; Naloxone; Nicotine; Smoking	1987
Alterations in nociception following adrenal medullary transplants into the rat periaqueductal gray. Experimental brain research, 1987, Volume: 67, Issue:2 Topics: Adrenal Medulla; Adrenergic Fibers; Animals; Endorphins; Female; Male; Naloxone; Nicotine; Pain; Periaqueductal Gray; Phentolamine; Rats; Rats, Inbred Strains	1987
Nicotine-induced release of vasopressin in the conscious rat: role of opioid peptides and hemodynamic effects. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:2 Topics: Animals; Consciousness; Dose-Response Relationship, Drug; Endorphins; Hemodynamics; Male; Naloxone; Nicotine; Rats; Rats, Inbred Strains; Vasopressins	1987
Catecholamines and opioid peptides in human phaeochromocytomas. Acta endocrinologica, 1986, Volume: 113, Issue:3 Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Cells, Cultured; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Endorphins; Enkephalin, Methionine; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Naloxone; Nicotine; Norepinephrine; Pheochromocytoma	1986
Adrenal medullary tissue transplants in the rat spinal cord reduce pain sensitivity. Brain research, 1986, Oct-01, Volume: 384, Issue:1 Topics: Adrenal Medulla; Analgesia; Animals; Chromaffin Granules; Endorphins; Female; Hot Temperature; Microscopy, Electron; Naloxone; Nicotine; Pain; Rats; Rats, Inbred Strains; Sensory Thresholds; Spinal Cord; Subarachnoid Space; Time Factors	1986
Naloxone effects on plasma vasopressin and oxytocin concentrations elevated by histamine, nicotine, isoproterenol and an acute increase in [NaCl] in cerebrospinal fluid. Neuroendocrinology, 1986, Volume: 44, Issue:2 Topics: Animals; Histamine; Hypothalamo-Hypophyseal System; Injections, Intraventricular; Isoproterenol; Male; Naloxone; Nicotine; Oxytocin; Rats; Rats, Inbred Strains; Sodium Chloride; Vasopressins	1986
A dopaminergic receptor modulates catecholamine release from the cat adrenal gland. The Journal of physiology, 1985, Volume: 362 Topics: Adrenal Glands; Adrenal Medulla; Animals; Apomorphine; Benzamides; Catecholamines; Cats; Dopamine; Female; Haloperidol; Male; Naloxone; Nicotine; Phentolamine; Receptors, Dopamine	1985
Cholinergic modification of naloxone-induced jumping in morphine dependent mice. European journal of pharmacology, 1974, Volume: 26, Issue:1 Topics: Animals; Arecoline; Atropine; Behavior, Animal; Benztropine; Brain Chemistry; Dimethylphenylpiperazinium Iodide; Humans; Lobeline; Male; Mecamylamine; Mice; Mice, Inbred ICR; Morphine Dependence; Naloxone; Nicotine; Oxotremorine; Parasympatholytics; Parasympathomimetics; Pempidine; Physostigmine; Pilocarpine; Tremorine; Tritium	1974
Release-modulating acetylcholine receptors in cholinergic neurones of the guinea-pig ileum. British journal of pharmacology, 1980, Volume: 68, Issue:2 Topics: Acetylcholine; Animals; Electric Stimulation; Ganglionic Blockers; Guinea Pigs; Ileum; In Vitro Techniques; Male; Naloxone; Neurons; Nicotine; Parasympathetic Nervous System; Receptors, Cholinergic; Serotonin	1980
Saturable (3H)cocaine binding in central nervous system of mouse. Life sciences, 1980, Sep-22, Volume: 27, Issue:12 Topics: Animals; Brain; Cell Membrane; Cocaine; Male; Mice; Morphine; Naloxone; Neurotransmitter Agents; Nicotine; Tubocurarine	1980
Regional release of [3H]dopamine from rat brain in vitro: effects of opioids on release induced by potassium, nicotine, and L-glutamic acid. Canadian journal of physiology and pharmacology, 1983, Volume: 61, Issue:1 Topics: Animals; Brain; Dopamine; Endorphins; Enkephalins; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Morphine; Naloxone; Narcotics; Nicotine; Potassium; Rats; Rats, Inbred Strains; Tetrodotoxin; Tritium	1983
Nerve-mediated non-adrenergic inhibitory responses of guinea-pig taenia caeci: further evidence of depression by morphine. The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:12 Topics: Animals; Atropine; Cecum; Dimethylphenylpiperazinium Iodide; Drug Interactions; Electric Stimulation; Guanethidine; Guinea Pigs; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naloxone; Nicotine; Tetrodotoxin	1983
Modulation of nicotinic receptors by opiate receptor agonists in cultured adrenal chromaffin cells. Nature, 1980, Jan-31, Volume: 283, Issue:5746 Topics: Adrenal Medulla; Animals; Catecholamines; Cattle; Cells, Cultured; Endorphins; Enkephalins; Kinetics; Morphine; Naloxone; Nicotine; Receptors, Cholinergic; Receptors, Nicotinic; Receptors, Opioid	1980
Memory facilitation by naloxone is due to release of dopaminergic and beta-adrenergic systems from tonic inhibition. Psychopharmacology, 1980, Volume: 67, Issue:3 Topics: Animals; Dextroamphetamine; Dopamine; Drug Interactions; Female; Haloperidol; Memory; Naloxone; Neural Inhibition; Nicotine; Phenoxybenzamine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tolazoline	1980
An analysis of nicotinic and opioid processes in the medulla oblongata and nucleus ambiguus of the dog. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:2 Topics: Animals; Blood Pressure; Cyclazocine; Decerebrate State; Dogs; Electric Stimulation; Endorphins; Ethylketocyclazocine; Female; Fentanyl; Heart Rate; Male; Mecamylamine; Medulla Oblongata; Naloxone; Nicotine; Phenazocine; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma	1983
Progress report from the NIDA Addiction Research Center Baltimore, Maryland (1984). NIDA research monograph, 1984, Volume: 55 Topics: Blood Pressure; Body Temperature; Compulsive Behavior; Cyclazocine; Discrimination Learning; Endorphins; Ethylketocyclazocine; Euphoria; Gambling; Glucose; Heart Rate; Humans; Morphine; Naloxone; Nicotine; Perception; Respiration; Substance-Related Disorders; Time Factors	1984
Naltrexone effects on plasma vasopressin concentration elevated and lowered by various stimuli. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:2 Topics: Animals; Arginine Vasopressin; Blood Pressure; Hematocrit; Male; Naloxone; Naltrexone; Nicotine; Rats; Rats, Inbred Strains; Sodium; Stress, Physiological; Water-Electrolyte Balance	1983
Effect of naloxone on change in breathing pattern with smoking. A hypothesis on the addictive nature of cigarette smoking. Chest, 1982, Volume: 82, Issue:5 Topics: Adult; Airway Resistance; Double-Blind Method; Endorphins; Female; Humans; Male; Middle Aged; Naloxone; Nicotine; Plethysmography; Pulmonary Ventilation; Random Allocation; Respiration; Respiratory Center; Smoking	1982
The role of liver tryptophan pyrrolase in the opposite effects of chronic administration and subsequent withdrawal of drugs of dependence on rat brain tryptophan metabolism. The Biochemical journal, 1981, Apr-15, Volume: 196, Issue:1 Topics: Animals; Brain; Humans; Liver; Male; Methylphenazonium Methosulfate; Morphine; Naloxone; Nicotine; Phenobarbital; Rats; Substance Withdrawal Syndrome; Tryptophan; Tryptophan Oxygenase	1981
Reversal by naloxone of the effects of chronic administration of drugs of dependence on rat liver and brain tryptophan metabolism. British journal of pharmacology, 1981, Volume: 74, Issue:2 Topics: Animals; Brain; Corticosterone; Ethanol; Humans; Liver; Naloxone; Nicotine; Phenobarbital; Rats; Serotonin; Substance-Related Disorders; Tryptophan	1981
Cardiovascular responses to cigarette smoke exposure in restrained conscious rats. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:2 Topics: Animals; Arginine Vasopressin; Atropine; Blood Pressure; Heart Rate; Lidocaine; Male; Muscarinic Antagonists; Naloxone; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Opioid; Restraint, Physical; Smoking; Stress, Psychological	1995
Naloxone precipitates nicotine abstinence syndrome in the rat. Psychopharmacology, 1993, Volume: 112, Issue:2-3 Topics: Animals; Male; Morphine; Naloxone; Nicotine; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Substance-Related Disorders	1993
Specific neurophysiological effects of systemic nicotine on neurons in the nucleus accumbens. Synapse (New York, N.Y.), 1993, Volume: 15, Issue:3 Topics: Action Potentials; Animals; Dopamine; Electric Stimulation; Haloperidol; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Morphine; Naloxone; Neurons; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley	1993
Absence of emetic effects of morphine and loperamide in Suncus murinus. European journal of pharmacology, 1994, May-02, Volume: 256, Issue:3 Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Injections, Subcutaneous; Loperamide; Male; Morphine; Naloxone; Nicotine; Serotonin; Serotonin Antagonists; Shrews; Vomiting	1994
Nicotine's opioid and anti-opioid interactions: proposed role in smoking behavior. European journal of pharmacology, 1993, Dec-01, Volume: 248, Issue:4 Topics: Analgesia; Animals; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Nicotine; Nociceptors; Smoking	1993
Gamma-aminobutyric acid mediation of the inhibitory effect of endogenous opioids on the arginine vasopressin and oxytocin responses to nicotine from cigarette smoking. Metabolism: clinical and experimental, 1993, Volume: 42, Issue:6 Topics: Adult; Analysis of Variance; Arginine Vasopressin; Drug Interactions; Endorphins; gamma-Aminobutyric Acid; Humans; Male; Naloxone; Nicotine; Oxytocin; Smoking; Valproic Acid	1993
Affinity ligands and related agents for brain muscarinic and nicotinic cholinergic receptors. Biochemical pharmacology, 1993, May-25, Volume: 45, Issue:10 Topics: Affinity Labels; Animals; Brain; Carbachol; Choline; Kinetics; Ligands; Mice; Naloxone; Nicotine; Oxotremorine; Procaine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Receptors, Nicotinic; Seizures; Tritium	1993
Opioids inhibit dopamine secretion from PC12 rat pheochromocytoma cells in a naloxone-reversible manner. Life sciences, 1996, Volume: 58, Issue:1 Topics: Analgesics; Analgesics, Opioid; Animals; Chromatography, High Pressure Liquid; Culture Media; Dopamine; Electrochemistry; Naloxone; Narcotic Antagonists; Nicotine; PC12 Cells; Potassium; Rats; Receptors, Opioid	1996
Developmental changes in neurotransmitter receptor binding in the human periaqueductal gray. Journal of neuropathology and experimental neurology, 1996, Volume: 55, Issue:4 Topics: Age Factors; Binding, Competitive; Brain; Humans; Lysergic Acid Diethylamide; Naloxone; Neurotransmitter Agents; Nicotine; Periaqueductal Gray; Receptors, Kainic Acid	1996
Nicotine alleviation of nicotine abstinence syndrome is naloxone-reversible. Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:1 Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Subcutaneous; Male; Naloxone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Substance-Related Disorders	1996
Nicotine attenuates naloxone-induced jumping behaviour in morphine-dependent mice. European journal of pharmacology, 1996, Feb-29, Volume: 298, Issue:1 Topics: Animals; Atropine; Behavior, Animal; Benzazepines; Hexamethonium; Male; Mecamylamine; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; Nicotine; Phenoxybenzamine; Propranolol; Substance P; Substance Withdrawal Syndrome; Sulpiride	1996
Sensitization to the conditioned rewarding effects of morphine: pharmacology and temporal characteristics. European journal of pharmacology, 1996, Mar-28, Volume: 299, Issue:1-3 Topics: Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Fentanyl; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Time Factors	1996
Brain-targeted delivery of a leucine-enkephalin analogue by retrometabolic design. Journal of medicinal chemistry, 1996, Nov-22, Volume: 39, Issue:24 Topics: Analgesia; Analgesics; Blood-Brain Barrier; Brain; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Drug Delivery Systems; Drug Design; Enkephalin, Leucine; Esterases; Lipase; Naloxone; Nicotine; Peptides; Prodrugs; Receptors, Opioid	1996
Preferences for tastes paired with a nicotine antagonist in rats chronically treated with nicotine. Pharmacology, biochemistry, and behavior, 1997, Volume: 56, Issue:2 Topics: Animals; Conditioning, Psychological; Fentanyl; Food Preferences; Male; Mecamylamine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Taste	1997
Contribution of adrenal hormones to nicotine-induced inhibition of synovial plasma extravasation in the rat. British journal of pharmacology, 1997, Volume: 120, Issue:2 Topics: Adrenal Glands; Animals; Bradykinin; Capillary Permeability; Male; Mecamylamine; Mifepristone; Naloxone; Nicotine; Platelet Activating Factor; Propanolamines; Rats; Rats, Sprague-Dawley	1997
Effect of prior nicotine treatment on drug induced changes in serum LH concentrations in rats. Life sciences, 1997, Volume: 60, Issue:25 Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dopamine Antagonists; Drug Administration Schedule; Drug Interactions; Gonadotropin-Releasing Hormone; Haloperidol; Luteinizing Hormone; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Stimulation, Chemical	1997
Developmental changes in heterogeneous patterns of neurotransmitter receptor binding in the human interpeduncular nucleus. The Journal of comparative neurology, 1998, Jan-19, Volume: 390, Issue:3 Topics: Adult; Animals; Child, Preschool; Embryonic and Fetal Development; Humans; Infant, Newborn; Kainic Acid; Lysergic Acid Diethylamide; Mesencephalon; Muscarinic Antagonists; Naloxone; Nicotine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Receptors, Muscarinic; Receptors, Neurotransmitter; Receptors, Nicotinic; Receptors, Serotonin; Species Specificity	1998
Nitric oxide mediates mecamylamine- and naloxone-precipitated nicotine withdrawal. European journal of pharmacology, 1998, Mar-19, Volume: 345, Issue:2 Topics: Animals; Male; Mecamylamine; Naloxone; NG-Nitroarginine Methyl Ester; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nitric Oxide; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome	1998
A dopamine-mu1 opioid link in the rat ventral tegmentum shared by palatable food (Fonzies) and non-psychostimulant drugs of abuse. The European journal of neuroscience, 1998, Volume: 10, Issue:3 Topics: Animals; Dopamine; Food Preferences; Male; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Substance-Related Disorders; Time Factors; Ventral Tegmental Area	1998
Ontogeny of the diurnal rhythm of tuberoinfundibular dopaminergic neuronal activity in peripubertal female rats: possible involvement of cholinergic and opioidergic systems. Neuroendocrinology, 1998, Volume: 68, Issue:6 Topics: Animals; Circadian Rhythm; Dopamine; Female; Limbic System; Male; Mecamylamine; Naloxone; Narcotic Antagonists; Neostriatum; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Opioid Peptides; Parasympathetic Nervous System; Prolactin; Rats; Rats, Sprague-Dawley; Sexual Maturation	1998
Intravenous injections of nicotine decrease the pulsatile secretion of LH by inhibiting the gonadotropin-releasing hormone (GnRH) pulse generator activity in female rats. Psychoneuroendocrinology, 1999, Volume: 24, Issue:4 Topics: Animals; Female; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; Injections, Intravenous; Luteinizing Hormone; Naloxone; Narcotic Antagonists; Nicotine; Ovariectomy; Periodicity; Rats; Rats, Wistar	1999
Modulation of emesis by fentanyl and opioid receptor antagonists in Suncus murinus (house musk shrew). European journal of pharmacology, 1999, Jun-11, Volume: 374, Issue:1 Topics: Animals; Antiemetics; Female; Fentanyl; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nicotine; Receptors, Opioid; Shrews; Vomiting	1999
Nociceptin inhibits the neurogenic vasopressor response in the pithed rat via prejunctional ORL1 receptors. Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:1 Topics: Animals; Autonomic Fibers, Preganglionic; Blood Pressure; Decerebrate State; Electric Stimulation; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Nervous System Physiological Phenomena; Neuromuscular Junction; Nicotine; Nicotinic Agonists; Nociceptin; Nociceptin Receptor; Norepinephrine; Opioid Peptides; Rats; Rats, Wistar; Receptors, Opioid; Sympathomimetics; Vagotomy	2000
Dissociation of physical abstinence signs from changes in extracellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats. Drug and alcohol dependence, 2000, Feb-01, Volume: 58, Issue:1-2 Topics: Analysis of Variance; Animals; Behavior, Animal; Dopamine; Infusion Pumps, Implantable; Male; Mecamylamine; Naloxone; Narcotic Antagonists; Nicotine; Nicotinic Antagonists; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome	2000
Reward and somatic changes during precipitated nicotine withdrawal in rats: centrally and peripherally mediated effects. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:3 Topics: Animals; Brain; Chlorisondamine; Injections, Intraventricular; Male; Mecamylamine; Naloxone; Nicotine; Rats; Rats, Wistar; Receptors, Nicotinic; Reward; Substance Withdrawal Syndrome	2000
Effects of repeated nicotine administration and footshock stress on rat mesoprefrontal dopamine systems: Evidence for opioid mechanisms. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 23, Issue:1 Topics: Animals; Dopamine; Immobilization; Male; Naloxone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Opioid Peptides; Prefrontal Cortex; Rats; Stress, Physiological	2000
Modulation of opioidergic system on mecamylamine-precipitated nicotine-withdrawal aversion in rats. Psychopharmacology, 2000, Volume: 151, Issue:1 Topics: Analgesics; Animals; Male; Mecamylamine; Naloxone; Narcotic Antagonists; Nicotine; Nicotinic Antagonists; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Substance Withdrawal Syndrome	2000
The possible cross-tolerance between morphine- and nicotine-induced hypothermia in mice. Pharmacology, biochemistry, and behavior, 2001, Volume: 68, Issue:2 Topics: Animals; Body Temperature; Drug Interactions; Drug Tolerance; Hexamethonium; Hypothermia, Induced; Male; Mecamylamine; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Nicotinic Antagonists	2001
Altered neuroadaptation in opiate dependence and neurogenic inflammatory nociception in alpha CGRP-deficient mice. Nature neuroscience, 2001, Volume: 4, Issue:4 Topics: Acetic Acid; Analgesics, Opioid; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Fixatives; Formaldehyde; Ganglionic Stimulants; Inflammation; Magnesium Sulfate; Mice; Mice, Transgenic; Morphine; Naloxone; Narcotic Antagonists; Nicotine; Opioid-Related Disorders; Pain; Substance Withdrawal Syndrome	2001
Endogenous opioids suppress activation of nociceptors by sub-nanomolar nicotine. British journal of pharmacology, 2001, Volume: 133, Issue:1 Topics: Adrenal Medulla; Analysis of Variance; Animals; Animals, Newborn; Bradykinin; Capsaicin; Dose-Response Relationship, Drug; Hexamethonium; Inflammation; Knee Joint; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Nicotine; Nociceptors; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Opioid; Sciatic Nerve; Time Factors	2001
Naloxone inhibits nicotine-induced receptor current and catecholamine secretion in bovine chromaffin cells. Brain research, 2001, Jun-08, Volume: 903, Issue:1-2 Topics: Animals; Catecholamines; Cattle; Chromaffin Cells; Dose-Response Relationship, Drug; Membrane Potentials; Naloxone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Opioid Peptides; Patch-Clamp Techniques; Receptors, Nicotinic	2001
Opioid receptor involvement in the adaptation to motion sickness in Suncus murinus. Pharmacology, biochemistry, and behavior, 2001, Volume: 68, Issue:4 Topics: Adaptation, Psychological; Analgesics, Opioid; Animals; Female; Ganglionic Stimulants; Male; Morphine; Motion Sickness; Naloxone; Narcotic Antagonists; Nicotine; Receptors, Opioid; Shrews; Vomiting	2001
Effects of adolescent nicotine exposure on opioid consumption and neuroendocrine responses in adult male and female rats. Experimental and clinical psychopharmacology, 2001, Volume: 9, Issue:3 Topics: Adrenocorticotropic Hormone; Aging; Analgesics, Opioid; Animals; Body Weight; Corticosterone; Drinking; Eating; Female; Fentanyl; Male; Naloxone; Narcotic Antagonists; Neurosecretory Systems; Nicotine; Nicotinic Agonists; Opioid-Related Disorders; Rats; Rats, Wistar; Sex Characteristics; Substance Withdrawal Syndrome	2001
Drug trace discrimination with nicotine and morphine in rats. Behavioural pharmacology, 2002, Volume: 13, Issue:1 Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Mecamylamine; Mental Recall; Morphine; Naloxone; Nicotine; Rats	2002
Cross-tolerance between morphine- and nicotine-induced conditioned place preference in mice. Pharmacology, biochemistry, and behavior, 2003, Volume: 74, Issue:2 Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Tolerance; Female; Mecamylamine; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Opioid	2003
An arterially perfused decerebrate preparation of Suncus murinus (house musk shrew) for the study of emesis and swallowing. Experimental physiology, 2002, Volume: 87, Issue:5 Topics: Animals; Aorta, Thoracic; Decerebrate State; Deglutition; Disease Models, Animal; Diterpenes; Electric Stimulation; Esophagus; Female; Heart Rate; Male; Naloxone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Perfusion; Phrenic Nerve; Physical Stimulation; Pyrimidinones; Reflex; Respiratory Mechanics; Shrews; Vagus Nerve; Video Recording; Vomiting	2002
Vagal modulation of spinal nicotine-induced inhibition of the inflammatory response mediated by descending antinociceptive controls. Neuropharmacology, 2003, Volume: 45, Issue:5 Topics: Adrenergic alpha-Antagonists; Animals; Bradykinin; Capillary Permeability; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Inflammation; Injections, Spinal; Knee Joint; Male; Naloxone; Narcotic Antagonists; Neural Inhibition; Nicotine; Phentolamine; Plasma; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Stimulation, Chemical; Vagotomy; Vagus Nerve	2003
Nicotine attenuates place aversion induced by naloxone in single-dose, morphine-treated rats. Psychopharmacology, 2004, Volume: 171, Issue:4 Topics: Animals; Avoidance Learning; Conditioning, Psychological; Male; Morphine; Naloxone; Nicotine; Rats; Rats, Sprague-Dawley	2004
Nicotine reversal effects of the benzoflavone moiety from Passiflora incarnata Linneaus in mice. Addiction biology, 2002, Volume: 7, Issue:4 Topics: Animals; Benzoflavones; Drug Administration Schedule; Drug Therapy, Combination; Female; Locomotion; Male; Mice; Naloxone; Narcotic Antagonists; Nicotine; Passiflora; Phytotherapy; Plant Preparations; Substance Withdrawal Syndrome; Tobacco Use Disorder	2002
Sensitivity of neuronal nicotinic acetylcholine receptors to the opiate antagonists naltrexone and naloxone: receptor blockade and up-regulation. Bioorganic & medicinal chemistry letters, 2004, Apr-19, Volume: 14, Issue:8 Topics: Cell Line; Gene Expression; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Nicotine; Patch-Clamp Techniques; Receptors, Nicotinic; Sensitivity and Specificity; Smoking Cessation; Structure-Activity Relationship; Time Factors; Up-Regulation	2004
Nicotine serves as a feature-positive modulator of Pavlovian appetitive conditioning in rats. Behavioural pharmacology, 2004, Volume: 15, Issue:3 Topics: Animals; Appetitive Behavior; Choice Behavior; Conditioning, Classical; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Administration Schedule; Hexamethonium; Male; Mecamylamine; Naloxone; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Reward	2004
Delta9-tetrahydrocannabinol decreases somatic and motivational manifestations of nicotine withdrawal in mice. The European journal of neuroscience, 2004, Volume: 20, Issue:10 Topics: Analgesics, Non-Narcotic; Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Benzoxazines; Brain; Calcium Channel Blockers; Cell Count; Conditioning, Operant; Dronabinol; Drug Administration Schedule; Drug Interactions; Immunohistochemistry; In Vitro Techniques; Male; Mecamylamine; Mice; Morpholines; Motivation; Naloxone; Naphthalenes; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Proto-Oncogene Proteins c-fos; Radioligand Assay; Substance Withdrawal Syndrome	2004
Mu-opioid receptor and CREB activation are required for nicotine reward. Neuron, 2005, Jun-16, Volume: 46, Issue:6 Topics: Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Blotting, Northern; Blotting, Western; Brain; Cell Count; Cocaine; Conditioning, Operant; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Immunohistochemistry; Immunoprecipitation; Mice; Mice, Inbred C57BL; Mice, Knockout; Naloxone; Narcotic Antagonists; Neurons; Nicotine; Phosphorylation; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; Reward; RNA, Messenger; Time Factors; Tobacco Use Disorder	2005
Intravenous nicotine self-administration in rats: effects of mecamylamine, hexamethonium and naloxone. Psychopharmacology, 2006, Volume: 184, Issue:3-4 Topics: Animals; Association Learning; Brain; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Hexamethonium; Humans; Infusions, Intravenous; Male; Mecamylamine; Naloxone; Nicotine; Nicotinic Antagonists; Rats; Rats, Long-Evans; Receptors, Nicotinic; Receptors, Opioid; Reinforcement Schedule	2006
Effects of alpha4beta2 and alpha7 nicotinic acetylcholine receptor antagonists on place aversion induced by naloxone in single-dose morphine-treated rats. European journal of pharmacology, 2005, Sep-05, Volume: 519, Issue:1-2 Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Conditioning, Operant; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic	2005
Neurosteroids in nicotine and morphine dependence. Psychopharmacology, 2006, Volume: 186, Issue:3 Topics: Analgesics, Opioid; Animals; Cerebral Cortex; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Antagonists; Pregnanolone; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome	2006
Antinociceptive effects of alcohol and nicotine: involvement of the opioid system. Brain research, 2006, Jun-30, Volume: 1097, Issue:1 Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Combinations; Ethanol; Male; Naloxone; Narcotic Antagonists; Nicotine; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid	2006
Influence of ATP-dependent K+ channels on nicotine-induced inhibition of withdrawal in morphine-dependent mice. European journal of pharmacology, 2006, Dec-15, Volume: 552, Issue:1-3 Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Behavior, Animal; Diarrhea; Diazoxide; Dose-Response Relationship, Drug; Ganglionic Stimulants; Glyburide; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Potassium Channels, Inwardly Rectifying; Substance Withdrawal Syndrome	2006
Repeated administration of nicotine attenuates the development of morphine tolerance and dependence in mice. Pharmacology, biochemistry, and behavior, 2008, Volume: 88, Issue:4 Topics: Analgesics, Opioid; Animals; Atropine; Dose-Response Relationship, Drug; Drug Tolerance; Ganglionic Blockers; Hexamethonium Compounds; Male; Mecamylamine; Mice; Morphine; Morphine Dependence; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pain Measurement; Substance Withdrawal Syndrome	2008
Involvement of spinal Met-enkephalin in nicotine-induced antinociception in mice. Brain research, 2008, Jan-16, Volume: 1189 Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Down-Regulation; Dynorphins; Enkephalin, Methionine; Enkephalins; Male; Mecamylamine; Mice; Mice, Inbred ICR; Naloxone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nociceptors; Pain; Pain Measurement; Pain Threshold; Posterior Horn Cells; Pro-Opiomelanocortin; Protein Precursors; RNA, Messenger	2008
Prosocial effects of nicotine and ethanol in adolescent rats through partially dissociable neurobehavioral mechanisms. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:12 Topics: Aging; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Central Nervous System Depressants; Diazepam; Dopamine Antagonists; Ethanol; Exploratory Behavior; Flupenthixol; Locomotion; Male; Naloxone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Rimonabant; Social Behavior	2009
Alteration of intravenous nicotine self-administration by opioid receptor agonist and antagonists in rats. Psychopharmacology, 2010, Volume: 210, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dose-Response Relationship, Drug; Feeding Behavior; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nicotine; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Self Administration; Tobacco Use Disorder	2010
Inhibitory inputs from rostromedial tegmental neurons regulate spontaneous activity of midbrain dopamine cells and their responses to drugs of abuse. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:5 Topics: Action Potentials; Analysis of Variance; Animals; Benzoxazines; Cannabinoids; Cocaine; Dopaminergic Neurons; Electric Stimulation; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Morphine; Morpholines; Naloxone; Naphthalenes; Narcotic Antagonists; Narcotics; Neural Inhibition; Neural Pathways; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Physical Stimulation; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Tegmentum Mesencephali; Time Factors; Ventral Tegmental Area	2012
Possible involvement of endogenous opioid system located downstream of α7 nicotinic acetylcholine receptor in mice with physical dependence on nicotine. Journal of pharmacological sciences, 2014, Volume: 124, Issue:1 Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Biomarkers; Corticosterone; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Naloxone; Narcotic Antagonists; Nicotine; Opioid Peptides; Substance Withdrawal Syndrome; Tobacco Use Disorder	2014
Attenuation by baclofen of nicotine rewarding properties and nicotine withdrawal manifestations. Psychopharmacology, 2014, Volume: 231, Issue:15 Topics: Animals; Anxiety; Avoidance Learning; Baclofen; Conditioning, Psychological; GABA-B Receptor Agonists; Male; Mice; Movement; Naloxone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Receptors, GABA-B; Reward; Space Perception; Substance Withdrawal Syndrome; Tobacco Use Disorder	2014
Effects of chronic mild stress on the development of drug dependence in rats. Behavioural pharmacology, 2014, Volume: 25, Issue:5-6 Topics: Animals; Chronic Disease; Citalopram; Depressive Disorder; Diazepam; Disease Models, Animal; Flumazenil; GABA Modulators; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Substance Withdrawal Syndrome; Substance-Related Disorders	2014
The mechanism of chronic nicotine exposure and nicotine withdrawal on pain perception in an animal model. Neuroscience letters, 2020, 01-10, Volume: 715 Topics: Animals; Baclofen; Bicuculline; Disease Models, Animal; Down-Regulation; Endorphins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hyperalgesia; Male; Naloxone; Nicotine; Pain Perception; Pain Threshold; Rats; Receptors, Opioid, mu; Spinal Cord; Substance Withdrawal Syndrome; Time Factors; Up-Regulation	2020