nicotine has been researched along with n-methylaspartate in 64 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.56) | 18.7374 |
| 1990's | 23 (35.94) | 18.2507 |
| 2000's | 20 (31.25) | 29.6817 |
| 2010's | 18 (28.13) | 24.3611 |
| 2020's | 2 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
| Aizenman, E; Reynolds, IJ; Tang, LH | 1 |
| Akaike, N; Harata, N; Tateishi, N | 1 |
| Johnson, KM; Snell, LD | 1 |
| Nisell, M; Nomikos, GG; Svensson, TH | 2 |
| Fröhlich, R; Illes, P; Patzelt, C | 1 |
| Breese, GR; Criswell, HE; Duncan, GE; Keir, WJ; McCown, TJ; Morrow, AL; Simson, PE | 1 |
| Desagher, S; Glowinski, J; Marin, P; Maus, M; Prémont, J | 1 |
| Ohno-Shosaku, T; Sawada, S; Yamamoto, C | 1 |
| Bickler, PE; Cardone, C; Szenohradszky, J; Yost, S | 1 |
| Breese, GR; Criswell, HE; Duncan, GE; Herbert, JS; McCown, TJ; Morrow, AL; Simson, PE | 1 |
| Chéramy, A; Glowinski, J; Godeheu, G; L'Hirondel, M | 1 |
| Fort, P; Jones, BE; Khateb, A; Mühlethaler, M; Serafin, M; Williams, S | 1 |
| Gallardo, KA; Leslie, FM | 1 |
| Bacchi, A; Carlson, NG; Gahring, LC; Rogers, SW | 1 |
| González, MP; Herrero, MT; Oset-Gasque, MJ; Vicente, S | 1 |
| Aramakis, VB; Metherate, R | 1 |
| Chen, YH; Fu, WM; Liou, HC | 1 |
| Ansaldo, MA; Fedele, E; Raiteri, M; Varnier, G | 1 |
| Lima, R; Titmus, MJ; Tsai, HJ; Udin, SB | 1 |
| Bacchi, A; Carlson, NG; Chen, J; Gahring, LC; Rogers, SW; Wieggel, WA | 1 |
| Carlson, NG; Gahring, LC; Howard, J; Rogers, SW; Wieggel, WA | 1 |
| Beyreuther, K; Emilien, G; Maloteaux, JM; Masters, CL | 1 |
| Dajas-Bailador, FA; Lima, PA; Wonnacott, S | 1 |
| Choi, WJ; Lim, DK; Park, SH | 1 |
| Harris, BR; Hauser, KF; Holley, RC; Littleton, JM; Mayer, S; Prendergast, MA | 1 |
| Albuquerque, EX; Alkondon, M; Hilmas, C; Pereira, EF; Rassoulpour, A; Schwarcz, R | 1 |
| Kim, HS; Lim, DK | 1 |
| Changeux, JP; Evrard, P; Gressens, P; Laudenbach, V; Medja, F; Rossi, FM; Zoli, M | 1 |
| Stolerman, I | 1 |
| de Vellis, J; Eterovic, VA; Ferchmin, PA; Perez, D | 1 |
| Gahring, LC; Meyer, EL; Rogers, SW | 1 |
| Grilli, M; Marchi, M; Molfino, F; Parodi, M; Raiteri, M; Risso, F | 1 |
| Harris, BR; Littleton, JM; Mulholland, PJ; Prendergast, MA; Self, RL | 1 |
| Bado, M; Grilli, M; Marchi, M; Parodi, M; Raiteri, M; Risso, F | 1 |
| Jardemark, K; Konradsson, A; Marcus, MM; Svensson, TH | 1 |
| Beltran-Parrazal, L; Charles, AC; de Vellis, J; Ferchmin, PA; Ghiani, CA; Lelievre, V; Malvar, J; Sforza, DM; Smith, DJ | 1 |
| DeChon, J; Hu, G; Hu, J; Liu, Q; Wu, J; Yan, KC | 1 |
| Arrick, DM; Mayhan, WG | 1 |
| Chen, CC; Chen, GD; Chen, MJ; Cheng, CL; Lee, SD; Liao, JM; Lin, TB; Pan, SF; Peng, HY; Shyu, JC | 1 |
| Chen, H; Sharp, BM; Wang, F | 1 |
| Grilli, M; Marchi, M; Merlo-Pich, E; Pittaluga, A | 1 |
| Nayer-Nouri, T; Rezayof, A; Shirazi-Zand, Z; Zarrindast, MR | 1 |
| Huang, LT; Lodge, D; Sherwood, JL; Sun, YJ; Wang, Y | 1 |
| Akaike, H; Akaike, N; Hori, N; Ito, Y; Jang, II; Ogawa, S | 1 |
| Dergacheva, O; Jameson, H; Lovett-Barr, MR; Mendelowitz, D; Wang, X | 1 |
| Bevins, RA; Murray, JE; Polewan, RJ; Walker, AW | 1 |
| Desaer, C; Ramakrishnan, L | 1 |
| Aghamohammadi-Sereshki, A; Rezayof, A; Rostami, P; Zarrindast, MR | 1 |
| Benavidez, JM; Blednov, YA; Harris, RA; Homanics, GE | 1 |
| Bartlett, MG; Beck, WD; Buccafusco, JJ; Callahan, PM; Chapman, JM; Hutchings, EJ; Li, P; Schade, RF; Terry, AV; Vandenhuerk, L | 1 |
| Sieber, M | 1 |
| Bach, D; Baker, D; Deats, S; Kotturu, D; Montgomery, E; Pagán, OR; Raffa, RB; Randolph, C; Rawls, S; Tallarida, C; Tenaglia, M; Wilk, G | 1 |
| Horiuchi, J; Miyashita, T; Morimoto, T; Oda, Y; Saitoe, M; Yin, JC | 1 |
| Chen, H; Matta, SG; Roguski, EE; Sharp, BM | 1 |
| Agostinho, P; Chen, J; Cunha, RA; Grilli, M; Marchi, M; Olivero, G; Pittaluga, A; Salamone, A; Tomé, AR; Zappettini, S | 1 |
| Ávila-Ruiz, T; Carranza, V; Flores, G; Flores-Hernández, J; Gustavo, LL; Limón, DI; Martínez, I | 1 |
| Kohlmeier, KA; McNair, LF | 1 |
| Bevins, RA; Charntikov, S; Li, M; Pittenger, ST; Swalve, N | 1 |
| Fan, Y; Jiao, Y; Kim, SC; Kim, YW; Lee, BH; Lee, CW; Liu, HF; Wu, T; Wu, YY; Yang, CH; Zhang, J; Zhao, RJ; Zhao, Z; Zhu, XD | 1 |
| Alijanpour, S; Farzamfard, P; Rezayof, A | 1 |
| Eterovic, VA; Ferchmin, PA; Ferrer-Acosta, Y; Martins, AH; Pérez, D; Rodriguez-Massó, S | 1 |
3 review(s) available for nicotine and n-methylaspartate
| Article | Year |
|---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
The neuroanatomical specificity of ethanol action on ligand-gated ion channels: a hypothesis.
Topics: Animals; Brain; Ethanol; gamma-Aminobutyric Acid; Glycine; Humans; Ion Channels; Ligands; Models, Neurological; Muscimol; N-Methylaspartate; Nicotine; Receptors, GABA-A | 1993 |
Prospects for pharmacological intervention in Alzheimer disease.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspartic Acid Endopeptidases; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Endopeptidases; Hippocampus; Humans; Indans; N-Methylaspartate; Nerve Growth Factors; Nicotine; Piperidines; Tacrine | 2000 |
61 other study(ies) available for nicotine and n-methylaspartate
| Article | Year |
|---|---|
Effects of nicotinic agonists on the NMDA receptor.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Ganglionic Stimulants; Glycine; Lobeline; N-Methylaspartate; Neurons; Nicotine; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1991 |
Modulatory action of cholinergic drugs on N-methyl-D-aspartate response in dissociated rat nucleus basalis of Meynert neurons.
Topics: Acetylcholine; Action Potentials; Age Factors; Animals; Carbachol; Drug Interactions; N-Methylaspartate; Neurons; Nicotine; Parasympathomimetics; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Substantia Innominata | 1991 |
Effects of nicotinic agonists and antagonists on N-methyl-D-aspartate-induced 3H-norepinephrine release and 3H-(1-[1-(2-thienyl)cyclohexyl]-piperidine) binding in rat hippocampus.
Topics: Animals; Aspartic Acid; Carbachol; Dimethylphenylpiperazinium Iodide; Ganglionic Stimulants; Hexamethonium; Hexamethonium Compounds; Hippocampus; In Vitro Techniques; Mecamylamine; N-Methylaspartate; Nicotine; Norepinephrine; Rats; Receptors, Nicotinic | 1989 |
Infusion of nicotine in the ventral tegmental area or the nucleus accumbens of the rat differentially affects accumbal dopamine release.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Dopamine; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; Mecamylamine; Microdialysis; N-Methylaspartate; Nicotine; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Nicotinic; Stereoisomerism; Ventral Tegmental Area | 1994 |
Inhibition by ethanol of excitatory amino acid receptors and nicotinic acetylcholine receptors at rat locus coeruleus neurons.
Topics: Action Potentials; Animals; Ethanol; Kainic Acid; Locus Coeruleus; Male; N-Methylaspartate; Nicotine; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, Nicotinic; Substance P | 1994 |
Nicotine: a new neuroprotective agent?
Topics: Animals; Cholinergic Agents; Humans; N-Methylaspartate; Nervous System Diseases; Nicotine; Receptors, N-Methyl-D-Aspartate | 1994 |
Nicotine protects cultured striatal neurones against N-methyl-D-aspartate receptor-mediated neurotoxicity.
Topics: Acetylcholine; Animals; Carbachol; Cells, Cultured; Dimethylphenylpiperazinium Iodide; Hexamethonium; Mice; N-Methylaspartate; Neostriatum; Nerve Degeneration; Nervous System Diseases; Neurons; Nicotine; Receptors, Cholinergic; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic | 1994 |
Long-term potentiation and depression in the dentate gyrus, and effects of nicotine.
Topics: Animals; Bicuculline; Electric Stimulation; Guinea Pigs; Hippocampus; Long-Term Potentiation; N-Methylaspartate; Nicotine; Synaptic Transmission; Time Factors | 1994 |
Activation of brain acetylcholine receptors by neuromuscular blocking drugs. A possible mechanism of neurotoxicity.
Topics: Acetylcholine; Anesthesia, General; Animals; Atracurium; Brain; Calcium; Convulsants; Dose-Response Relationship, Drug; Enflurane; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Isoquinolines; Kainic Acid; Male; N-Methylaspartate; Neuromuscular Nondepolarizing Agents; Neurotoxins; Nicotine; Pancuronium; Phenytoin; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Time Factors; Tubocurarine; Vecuronium Bromide | 1994 |
Systemic nicotine-induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area.
Topics: Acetylglucosamine; Animals; Chromatography, High Pressure Liquid; Dopamine; Extracellular Space; Male; Mecamylamine; Microdialysis; N-Methylaspartate; Nicotine; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Nicotinic; Tetrodotoxin; Ventral Tegmental Area | 1994 |
Molecular basis for regionally specific action of ethanol on gamma-aminobutyric acidA receptors: generalization to other ligand-gated ion channels.
Topics: Animals; Brain Mapping; Ethanol; Gene Expression; Glycine; In Situ Hybridization; Ion Channel Gating; Male; N-Methylaspartate; Nicotine; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA; RNA, Messenger; Zolpidem | 1993 |
Cooperative contributions of cholinergic and NMDA receptors in the presynaptic control of dopamine release from synaptosomes of the rat striatum.
Topics: Acetylcholine; Animals; Corpus Striatum; Dopamine; Magnesium; Male; N-Methylaspartate; Nicotine; Oxotremorine; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic; Synaptosomes | 1996 |
Modulation of cholinergic nucleus basalis neurons by acetylcholine and N-methyl-D-aspartate.
Topics: Acetylcholine; Action Potentials; Animals; Carbachol; Choline O-Acetyltransferase; Cholinergic Fibers; Excitatory Amino Acid Agonists; Guinea Pigs; Muscarine; Muscarinic Agonists; N-Methylaspartate; Nicotine; Nicotinic Agonists; Organ Culture Techniques; Patch-Clamp Techniques; Prosencephalon; Sleep; Substantia Innominata; Tetrodotoxin | 1997 |
Nicotine-stimulated release of [3H]norepinephrine from fetal rat locus coeruleus cells in culture.
Topics: Alkaloids; Animals; Azocines; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cells, Cultured; Dimethylphenylpiperazinium Iodide; Fetus; Locus Coeruleus; N-Methylaspartate; Neurons; Nicotine; Nicotinic Agonists; Norepinephrine; Potassium Chloride; Pyridines; Quinolizines; Rats; Rats, Sprague-Dawley; Rhombencephalon; Structure-Activity Relationship; Tetrodotoxin; Tritium | 1998 |
Nicotine blocks TNF-alpha-mediated neuroprotection to NMDA by an alpha-bungarotoxin-sensitive pathway.
Topics: Animals; Bungarotoxins; Cell Survival; Cells, Cultured; Cerebral Cortex; Drug Combinations; Excitatory Amino Acid Agonists; Humans; Isomerism; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Nicotine; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha | 1998 |
Effect of glutamate receptor agonists on catecholamine secretion in bovine chromaffin cells.
Topics: Adrenal Medulla; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Cycloleucine; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Nicotine; Receptors, Glutamate | 1998 |
Nicotine selectively enhances NMDA receptor-mediated synaptic transmission during postnatal development in sensory neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholinesterase; Age Factors; alpha7 Nicotinic Acetylcholine Receptor; Animals; Critical Period, Psychological; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Male; Membrane Potentials; N-Methylaspartate; Neurons; Nicotine; Nicotinic Agonists; Organ Culture Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Somatosensory Cortex; Synaptic Transmission | 1998 |
Nerve terminal currents induced by autoreception of acetylcholine release.
Topics: Acetylcholine; Animals; Atropine; Autoreceptors; Calcium; Excitatory Amino Acid Agonists; Hexamethonium; Muscarinic Antagonists; N-Methylaspartate; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Presynaptic Terminals; Receptors, Nicotinic; Synaptic Transmission; Xenopus | 1998 |
Nicotine administration stimulates the in vivo N-methyl-D-aspartate receptor/nitric oxide/cyclic GMP pathway in rat hippocampus through glutamate release.
Topics: Amino Acids; Animals; Cyclic GMP; Ganglionic Stimulants; Glutamic Acid; Guanylate Cyclase; Hippocampus; Injections, Intraperitoneal; Male; N-Methylaspartate; Nicotine; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1998 |
Effects of choline and other nicotinic agonists on the tectum of juvenile and adult Xenopus frogs: a patch-clamp study.
Topics: Aging; Alkaloids; Animals; Axons; Azocines; Carbachol; Choline; Excitatory Postsynaptic Potentials; Mecamylamine; Metamorphosis, Biological; Models, Neurological; N-Methylaspartate; Nerve Regeneration; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Quinolizines; Receptors, Cholinergic; Receptors, Nicotinic; Superior Colliculi; Vision, Binocular; Visual Pathways; Xenopus laevis | 1999 |
Inflammatory cytokines IL-1 alpha, IL-1 beta, IL-6, and TNF-alpha impart neuroprotection to an excitotoxin through distinct pathways.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Immune Sera; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-6; Mice; N-Methylaspartate; Nerve Growth Factors; Neuroimmunomodulation; Neurons; Neurotoxins; Nicotine; Nicotinic Antagonists; Receptors, Interleukin-1; Sialoglycoproteins; Signal Transduction; Tumor Necrosis Factor-alpha | 1999 |
Alcohol blocks TNFalpha but not other cytokine-mediated neuroprotection to NMDA.
Topics: Animals; Cells, Cultured; Central Nervous System Depressants; Cerebral Cortex; Ethanol; Excitatory Amino Acid Agonists; Interleukin-1; Interleukin-6; Mice; N-Methylaspartate; Neurons; Nicotine; Nicotinic Agonists; Signal Transduction; Tumor Necrosis Factor-alpha | 1999 |
The alpha7 nicotinic acetylcholine receptor subtype mediates nicotine protection against NMDA excitotoxicity in primary hippocampal cultures through a Ca(2+) dependent mechanism.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Calcium; Calcium Radioisotopes; Cell Survival; Cells, Cultured; Cytoplasm; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; N-Methylaspartate; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic | 2000 |
Subacute nicotine exposure in cultured cerebellar cells increased the release and uptake of glutamate.
Topics: Animals; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Female; Glutamate-Ammonia Ligase; Glutamic Acid; Male; N-Methylaspartate; Nicotine; Rats; Rats, Sprague-Dawley | 2000 |
Chronic nicotine exposure reduces N-methyl-D-aspartate receptor-mediated damage in the hippocampus without altering calcium accumulation or extrusion: evidence of calbindin-D28K overexpression.
Topics: Animals; Autoradiography; Calbindin 1; Calbindins; Calcium; Calcium Radioisotopes; Cell Death; Dose-Response Relationship, Drug; Drug Administration Schedule; Hippocampus; Immunohistochemistry; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; S100 Calcium Binding Protein G | 2001 |
The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Binding, Competitive; Brain; Cells, Cultured; Choline; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrophysiology; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; N-Methylaspartate; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic | 2001 |
Changes in the glutamate release and uptake of cerebellar cells in perinatally nicotine-exposed rat pups.
Topics: Animals; Animals, Newborn; Cerebellum; Dizocilpine Maleate; Female; Glutamic Acid; Male; N-Methylaspartate; Neurons; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2001 |
Selective activation of central subtypes of the nicotinic acetylcholine receptor has opposite effects on neonatal excitotoxic brain injuries.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Animals, Newborn; Autoradiography; Brain Diseases; Cell Death; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Ibotenic Acid; Injections; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Neurological; N-Methylaspartate; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Antagonists; Receptors, Nicotinic | 2002 |
Hits and misses in nicotine psychopharmacology: a personal view of research over a period of 30 years.
Topics: Binding Sites; Dopamine; Humans; N-Methylaspartate; Nicotine; Psychopharmacology; Receptors, Nicotinic; Smoking Cessation; Smoking Prevention | 2002 |
Nicotinic receptors differentially regulate N-methyl-D-aspartate damage in acute hippocampal slices.
Topics: Animals; Excitatory Amino Acid Agonists; Female; Hippocampus; In Vitro Techniques; N-Methylaspartate; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2003 |
Nicotine-induced neuroprotection against N-methyl-D-aspartic acid or beta-amyloid peptide occur through independent mechanisms distinguished by pro-inflammatory cytokines.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Cells, Cultured; Ceramides; Cerebral Cortex; Cytokines; Cytoprotection; Inflammation Mediators; Mice; Mice, Transgenic; Mutation; N-Methylaspartate; Neurons; Neuroprotective Agents; NF-kappa B; Nicotine; Peptide Fragments; Receptors, Nicotinic; Signal Transduction; Transgenes | 2003 |
Chronic nicotine causes functional upregulation of ionotropic glutamate receptors mediating hippocampal noradrenaline and striatal dopamine release.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Excitatory Amino Acid Agonists; Hippocampus; Male; N-Methylaspartate; Neostriatum; Nicotine; Nicotinic Agonists; Norepinephrine; Potassium; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptosomes; Up-Regulation | 2004 |
(-)-nicotine ameliorates corticosterone's potentiation of N-methyl-d-aspartate receptor-mediated cornu ammonis 1 toxicity.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Cell Survival; Corticosterone; Disease Models, Animal; Drug Interactions; Hippocampus; In Vitro Techniques; Male; Mifepristone; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic | 2004 |
Nicotine exerts a permissive role on NMDA receptor function in hippocampal noradrenergic terminals.
Topics: Animals; Calcium; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Male; Mecamylamine; N-Methylaspartate; Nerve Endings; Nicotine; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptosomes | 2004 |
The combination of nicotine with the D2 antagonist raclopride or the weak D4 antagonist L-745,870 generates a clozapine-like facilitation of NMDA receptor-mediated neurotransmission in pyramidal cells of the rat medial prefrontal cortex.
Topics: Analysis of Variance; Animals; Dopamine Antagonists; Drug Combinations; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; N-Methylaspartate; Nicotine; Prefrontal Cortex; Pyramidal Cells; Pyridines; Pyrroles; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2005 |
Gene expression is differentially regulated by neurotransmitters in embryonic neuronal cortical culture.
Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Gene Expression Regulation, Developmental; N-Methylaspartate; Neurons; Neurotransmitter Agents; Nicotine; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-fos; Rats; Receptors, Cholinergic; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 2006 |
Iptakalim inhibits nicotinic acetylcholine receptor-mediated currents in dopamine neurons acutely dissociated from rat substantia nigra pars compacta.
Topics: Acetylcholine; Action Potentials; Animals; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Propylamines; Rats; Rats, Wistar; Receptors, Nicotinic; Substantia Nigra | 2006 |
Acute infusion of nicotine impairs nNOS-dependent reactivity of cerebral arterioles via an increase in oxidative stress.
Topics: Animals; Antioxidants; Arterioles; Brain; Cyclic N-Oxides; Dose-Response Relationship, Drug; Infusions, Intravenous; Kainic Acid; Male; N-Methylaspartate; Nicotine; Nicotinic Agonists; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroglycerin; Oxidative Stress; Rats; Rats, Sprague-Dawley; Spin Labels; Superoxides; Vasodilation; Vasodilator Agents | 2007 |
Nicotine-activated descending facilitation on spinal NMDA-dependent reflex potentiation from pontine tegmentum in rats.
Topics: Action Potentials; Animals; Catheterization; Electric Stimulation; Female; Injections, Spinal; Microinjections; N-Methylaspartate; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Piperazines; Pons; Pyridines; Rats; Rats, Wistar; Receptors, Nicotinic; Reflex; Serotonin; Serotonin Antagonists; Spinal Cord | 2008 |
Neuroadaptive changes in the mesocortical glutamatergic system during chronic nicotine self-administration and after extinction in rats.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Electrochemistry; Excitatory Amino Acid Agents; Extinction, Psychological; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; N-Methylaspartate; Nicotine; Nicotinic Agonists; Potassium Chloride; Prefrontal Cortex; Rats; Rats, Inbred Lew; Self Administration; Ventral Tegmental Area | 2008 |
NMDA-mediated modulation of dopamine release is modified in rat prefrontal cortex and nucleus accumbens after chronic nicotine treatment.
Topics: Analysis of Variance; Animals; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Male; N-Methylaspartate; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Pipecolic Acids; Potassium; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Synaptosomes; Time Factors; Tritium | 2009 |
Nicotine improves ethanol-induced memory impairment: the role of dorsal hippocampal NMDA receptors.
Topics: Animals; Avoidance Learning; Central Nervous System Depressants; Dizocilpine Maleate; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Male; Memory; Memory Disorders; Mice; N-Methylaspartate; Nicotine; Nicotinic Agonists; Receptors, N-Methyl-D-Aspartate | 2010 |
Activation of presynaptic alpha7 nicotinic receptors evokes an excitatory response in hippocampal CA3 neurones in anaesthetized rats: an in vivo iontophoretic study.
Topics: 2-Amino-5-phosphonovalerate; Aconitine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; D-Aspartic Acid; Glutamic Acid; Hippocampus; Male; N-Methylaspartate; Neurons; Nicotine; Nicotinic Antagonists; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Presynaptic; Spiro Compounds | 2010 |
Effects of Z-338, a novel gastroprokinetic agent, on the actions of excitatory and inhibitory neurotransmitters on neurons in area postrema.
Topics: Adenosine Triphosphate; Animals; Area Postrema; Benzamides; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Ganglionic Stimulants; Gastrointestinal Agents; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Kainic Acid; Male; N-Methylaspartate; Neurons; Nicotine; Patch-Clamp Techniques; Rats; Rats, Wistar; Thiazoles; Vagus Nerve | 2010 |
The lateral paragigantocellular nucleus modulates parasympathetic cardiac neurons: a mechanism for rapid eye movement sleep-dependent changes in heart rate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Heart; Heart Rate; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Medulla Oblongata; N-Methylaspartate; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Sprague-Dawley; Sleep, REM; Time Factors; Vagus Nerve; Valine | 2010 |
An examination of NMDA receptor contribution to conditioned responding evoked by the conditional stimulus effects of nicotine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Conditioning, Classical; Cyclopentanes; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Mecamylamine; N-Methylaspartate; Nicotine; Phencyclidine; Phenols; Piperazines; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2011 |
Carbamazepine inhibits distinct chemoconvulsant-induced seizure-like activity in Dugesia tigrina.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Convulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; GABA Antagonists; N-Methylaspartate; Nicotine; Nicotinic Agonists; Oxcarbazepine; Picrotoxin; Planarians; Seizures; Structure-Activity Relationship | 2011 |
Nicotine-induced anxiogenic-like behaviours of rats in the elevated plus-maze: possible role of NMDA receptors of the central amygdala.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Anxiety; Male; Maze Learning; N-Methylaspartate; Nicotine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2012 |
Behavioral characterization of knockin mice with mutations M287L and Q266I in the glycine receptor α1 subunit.
Topics: 1-Butanol; Alcohol Drinking; Alcohol Withdrawal Seizures; Amino Acid Substitution; Animals; Behavior, Animal; Central Nervous System Depressants; Conditioning, Classical; Drug Synergism; Eating; Ethanol; Female; Food Preferences; Gene Knock-In Techniques; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Motor Skills; Mutation; N-Methylaspartate; Nicotine; Pentylenetetrazole; Quinine; Receptors, Glycine; Reflex, Righting; Reflex, Startle; Rotarod Performance Test; Saccharin; Seizures; Sex Characteristics; Strychnine; Taste Perception | 2012 |
The nicotine metabolite, cotinine, attenuates glutamate (NMDA) antagonist-related effects on the performance of the five choice serial reaction time task (5C-SRTT) in rats.
Topics: Animals; Behavior, Animal; Brain; Chromatography, High Pressure Liquid; Cotinine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Stability; Male; N-Methylaspartate; Nicotine; Psychomotor Performance; Rats; Rats, Wistar; Reaction Time; Tandem Mass Spectrometry; Tissue Distribution | 2012 |
Neuroprotective properties of nicotine.
Topics: Animals; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Chickens; Cortical Spreading Depression; In Vitro Techniques; N-Methylaspartate; Neuroprotective Agents; Nicotine; Pyridines; Receptors, N-Methyl-D-Aspartate; Retina; Video Recording | 2012 |
Planarians in pharmacology: parthenolide is a specific behavioral antagonist of cocaine in the planarian Girardia tigrina.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cocaine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Agonists; Methamphetamine; N-Methylaspartate; Nicotine; Nicotinic Agonists; Planarians; Regeneration; Seizures; Sesquiterpenes | 2012 |
Mg(2+) block of Drosophila NMDA receptors is required for long-term memory formation and CREB-dependent gene expression.
Topics: Activins; Analysis of Variance; Animals; Animals, Genetically Modified; Carrier Proteins; Cells, Cultured; Central Nervous System; Conditioning, Psychological; CREB-Binding Protein; Dose-Response Relationship, Drug; Drosophila; Drosophila Proteins; Electric Stimulation; Excitatory Amino Acid Agonists; Homer Scaffolding Proteins; Long-Term Potentiation; Magnesium; Mitogen-Activated Protein Kinase Kinases; Mutagenesis; N-Methylaspartate; Neurons; Nicotine; Nicotinic Agonists; Odorants; Olfactory Pathways; Patch-Clamp Techniques; Pupa; Receptors, N-Methyl-D-Aspartate; RNA-Binding Proteins | 2012 |
Full-gestational exposure to nicotine and ethanol augments nicotine self-administration by altering ventral tegmental dopaminergic function due to NMDA receptors in adolescent rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blotting, Western; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Dopaminergic Neurons; Electrochemistry; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Microinjections; N-Methylaspartate; Nicotine; Nicotinic Agonists; Polymerase Chain Reaction; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Self Administration; Ventral Tegmental Area | 2014 |
Prolonged nicotine exposure down-regulates presynaptic NMDA receptors in dopaminergic terminals of the rat nucleus accumbens.
Topics: Animals; Calcium; Dopamine; Dopaminergic Neurons; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nucleus Accumbens; Potassium Channel Blockers; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Synaptosomes | 2014 |
Chronic administration of nicotine enhances NMDA-activated currents in the prefrontal cortex and core part of the nucleus accumbens of rats.
Topics: Animals; Body Weight; Cells, Cultured; Ganglionic Stimulants; In Vitro Techniques; Magnesium Compounds; Male; Membrane Potentials; Motor Activity; N-Methylaspartate; Neurons; Neurotransmitter Agents; Nicotine; Nucleus Accumbens; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2014 |
Prenatal nicotine is associated with reduced AMPA and NMDA receptor-mediated rises in calcium within the laterodorsal tegmentum: a pontine nucleus involved in addiction processes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Female; Glutamic Acid; Humans; Mice; Motivation; N-Methylaspartate; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Substance-Related Disorders; Tegmentum Mesencephali | 2015 |
Double dissociation of the anterior and posterior dorsomedial caudate-putamen in the acquisition and expression of associative learning with the nicotine stimulus.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Association Learning; Caudate Nucleus; Conditioning, Psychological; Drug Administration Routes; Excitatory Amino Acid Agonists; Lidocaine; Male; N-Methylaspartate; Nicotine; Nicotinic Agonists; Putamen; Rats; Rats, Sprague-Dawley | 2017 |
Acupuncture reduces nicotine-induced norepinephrine release in the hypothalamus via the solitary NMDA receptor/NOS pathway.
Topics: Acupuncture Therapy; Animals; Corticosterone; Infusions, Intravenous; Male; Microdialysis; N-Methylaspartate; Nicotine; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Nitroprusside; Norepinephrine; Paraventricular Hypothalamic Nucleus; Phosphorylation; Rats; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2019 |
Ventral hippocampal NMDA receptors mediate the effects of nicotine on stress-induced anxiety/exploratory behaviors in rats.
Topics: Animals; Anxiety; Exploratory Behavior; Hippocampus; Male; N-Methylaspartate; Nicotine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2022 |
Memantine has a nicotinic neuroprotective pathway in acute hippocampal slices after an NMDA insult.
Topics: Hippocampus; Memantine; N-Methylaspartate; Neuroprotection; Neuroprotective Agents; Nicotine; Phosphatidylinositol 3-Kinases; Receptors, N-Methyl-D-Aspartate | 2022 |