nicotine has been researched along with methyllycaconitine in 168 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.60) | 18.7374 |
| 1990's | 25 (14.88) | 18.2507 |
| 2000's | 85 (50.60) | 29.6817 |
| 2010's | 53 (31.55) | 24.3611 |
| 2020's | 4 (2.38) | 2.80 |
| Authors | Studies |
|---|---|
| Albuquerque, EX; Lunt, GG; Macallan, DR; Rapoport, H; Swanson, KL; Wonnacott, S | 1 |
| Barrantes, GE; Murphy, CT; Westwick, J; Wonnacott, S | 1 |
| Barrantes, GE; Westwick, J; Wonnacott, S | 1 |
| Khan, IM; Printz, MP; Taylor, P; Yaksh, TL | 1 |
| Khan, IM; Taylor, P; Yaksh, TL | 1 |
| Chiappinelli, VA; Wolf, KM; Yum, L | 1 |
| Brioni, JD; Kim, DJ; O'Neill, AB | 1 |
| Hutson, P; Sullivan, JP; Wilkie, GI; Wonnacott, S | 1 |
| Changeux, JP; Léna, C | 1 |
| Blank, U; Clauss, W; Rückes, C; Weber, WM | 1 |
| Delbono, O; Grigorenko, E; Messi, ML; Renganathan, M | 1 |
| Akaike, A; Kaneko, S; Kimura, J; Kochiyama, H; Kume, T; Maeda, T; Shimohama, S | 1 |
| Atluri, P; Drisdel, RC; Fox, AP; Green, WN; Harkins, AB; Ko, E; Rakhilin, S; Rangwala, F; Salman, SS | 1 |
| Beaudet, AL; Dani, JA; De Biasi, M; Goldberg, L; Göldner, FM; Lorenzo, I; Orr-Urtreger, A; Patrick, JW; Saeki, M | 1 |
| Arneric, SP; Delbono, O; Gopalakrishnan, M; Messi, ML; Molinari, EJ; Renganathan, M; Sullivan, JP | 1 |
| Nomikos, GG; Schilström, B; Svensson, HM; Svensson, TH | 1 |
| Buhler, AV; Dunwiddie, TV; Frazier, CJ; Weiner, JL | 1 |
| Dezaki, K; Kimura, I; Nojima, H; Tsuneki, H | 1 |
| Clarke, PB; Gioanni, Y; Lepousé, C; Rougeot, C; Thierry, AM; Vidal, C | 1 |
| Arneric, SP; Briggs, CA; Gopalakrishnan, M; McKenna, DG; Monteggia, LM; Roch, JM; Sullivan, JP; Touma, E | 1 |
| Fryer, J; Herl, J; Leonard, SS; Lucero, L; Lukas, RJ; Peng, JH | 1 |
| Blagbrough, IS; Davies, AR; Hardick, DJ; Potter, BV; Wolstenholme, AJ; Wonnacott, S | 1 |
| Bertrand, D; Chiodini, FC; Hulo, S; Muller, D; Tassonyi, E | 1 |
| Breese, GR; Criswell, HE; Yang, X | 2 |
| Nordberg, A; Svensson, AL | 1 |
| Costa, E; Javaid, JI; Lecca, D; Shim, I | 1 |
| Fujii, S; Jia, Y; Sumikawa, K; Yang, A | 1 |
| Blondel, A; Moser, PC; Sanger, DJ | 1 |
| Kastellakis, A; Nomikos, G; Panagis, G; Spyraki, C | 1 |
| Davis, CB; Lee, DH; Shank, RP; Wang, HY | 1 |
| Grillner, P; Svensson, TH | 1 |
| Changeux, JP; Klink, R; Korn, H; Léna, C; Tsuneki, H | 1 |
| Adams, CE; Breese, CR; Collins, AC; Gillen, KM; Lee, MJ; Leonard, S; Logel, J; Marks, MJ; Sullivan, B | 1 |
| Gommans, J; Shoaib, M; Stolerman, IP | 1 |
| Breese, CR; Lee, MJ; Leonard, S; Strook, ML | 1 |
| Bertrand, D; Buisson, B | 1 |
| Fujii, S; Sumikawa, K | 2 |
| Ito, S; Kasai, Y; Nakazato, Y; Ohta, T; Yonekubo, K | 1 |
| Acosta, S; Miles, R; Strahlendorf, HK; Strahlendorf, JC | 1 |
| Tuominen, RK; Vainio, PJ | 1 |
| Cherubini, E; Maggi, L; Sher, E | 1 |
| Genzen, JR; McGehee, DS; Van Cleve, W | 1 |
| Markou, A; Paterson, NE | 1 |
| Hatanaka, H; Ikeuchi, T; Nakayama, H; Numakawa, T | 1 |
| Bettany, JH; Levin, ED | 1 |
| Buccafusco, JJ; Jonnala, RR; Terry, AV | 1 |
| Collins, AC; Marks, M; McIntosh, JM; Mogg, AJ; Whiteaker, P; Wonnacott, S | 1 |
| Lee, TJ; Si, ML | 1 |
| Bunnemann, B; Chiamulera, C; Merlo Pich, E; Mugnaini, M; Tarter, G; Tessari, M | 1 |
| Laviolette, SR; van der Kooy, D | 1 |
| File, SE; Genn, RF; Tucci, SA | 1 |
| Freir, DB; Herron, CE | 1 |
| George, AA; Kuo, YP; Lukas, RJ; Peng, JH; Purandare, MS; Schroeder, KM; Wu, J; Zhao, L | 1 |
| Ayers, JT; Crooks, PA; Dwoskin, LP; Grinevich, VP; Haubner, AJ; Sumithran, SP | 1 |
| File, SE; Genn, RF; Marco, E; Tucci, S | 1 |
| Mameli-Engvall, M; Nomikos, GG; Rawal, N; Schilström, B; Svensson, TH | 1 |
| Alreja, M; Hajszan, T; Leranth, C; Wu, M | 1 |
| Bräuner-Osborne, H; Falch, E; Frølund, B; Jensen, AA; Krogsgaard-Larsen, P; Mikkelsen, I | 1 |
| Elgoyhen, AB; Plazas, PV; Verbitsky, M | 1 |
| Höglund, AU; Kommalage, M | 1 |
| Al-Namaeh, M; Manaye, KF; Taylor, RE; Tizabi, Y | 1 |
| de Châtel, R; Göõz, M; Göõz, P; Smolka, AJ; Szalay, KS; Tóth, M; Vakkuri, O | 1 |
| Crawford, N; Finlayson, K; Kelly, JS; Marston, HM; Sharkey, J; Spratt, C; Young, JW | 1 |
| Kohama, K; Li, S; Nakamura, A; Tanaka, H; Xin, H; Ye, LH; Zhang, X; Zhao, T | 1 |
| Allen, DD; Ayers, JT; Crooks, PA; Deaciuc, AG; Dwoskin, LP; Grinevich, VP; Sumithran, SP; Wilkins, LH; Xu, R | 1 |
| Harris, BR; Littleton, JM; Mulholland, PJ; Prendergast, MA; Self, RL | 1 |
| Crooks, PA; Dwoskin, LP; Grinevich, VP; Miller, DK; Norrholm, SD; Zheng, G | 1 |
| Amano, T; Inoue, A; Matsubayashi, H; Nakata, Y; Sakai, N; Sasa, M; Seki, T | 1 |
| Frenz, CM; Gueorguiev, VD; Ronald, KM; Sabban, EL | 1 |
| Ellsworth, K; Javedan, SP; Kimura, R; Lukas, RJ; Marxer-Miller, S; Murray, TA; Song, C; Wakui, M; Wu, J | 1 |
| Ahtee, L; Nuutinen, S; Tuominen, RK | 1 |
| Abbruscato, TJ; Allen, DD; Lockman, PR; Van der Schyf, CJ | 1 |
| Davis, JA; Gould, TJ | 1 |
| Lajtha, A; Rossi, S; Sershen, H; Shearman, E; Singer, S | 1 |
| Araki, H; Gomita, Y; Jin, C; Kawasaki, H; Kawasaki, Y; Motoshima, S; Suemaru, K | 1 |
| Hamaue, N; Jia, Y; Sumikawa, K; Yamazaki, Y | 1 |
| Arias, E; Gallego-Sandín, S; García, AG; López, MG; Villarroya, M | 1 |
| Crooks, PA; Deaciuc, AG; Dwoskin, LP; Sumithran, SP; Wilkins, LH; Xu, R; Zhu, J | 1 |
| Giocomo, LM; Hasselmo, ME | 1 |
| Matteoni, C; Nistri, A; Sokolova, E | 1 |
| Arias, E; Buccafusco, JJ; Jonnala, RR; Li, XD; Mruthinti, S | 1 |
| Chen, JT; Chen, XT; Lou, ZY; Luo, L; Ruan, DY; Sun, LG; Wang, HL; Wang, M; Wang, S | 1 |
| Guan, X; Nakauchi, S; Sumikawa, K | 1 |
| Briggs, CA; Gubbins, EJ; Marks, MJ; Meyer, MD; Putman, CB; Surowy, CS; Thimmapaya, R | 1 |
| Icenogle, L; Levin, ED; Pocivavsek, A | 1 |
| Filip, M; McCreary, AC; Przegaliński, E; Zaniewska, M | 1 |
| Carney, SL; Serres, F | 1 |
| Caballero-Rivera, D; Lasalde-Dominicci, JA; Navedo, MF; Nieves-Cintrón, M | 1 |
| Abraham, P; Damaj, MI; Ivy Carroll, F; Ma, W; Martin, BR; Navarro, HA; Wolckenhauer, SA | 1 |
| Besson, M; Cazala, P; Changeux, JP; Cloëz-Tayarani, I; Cormier, A; David, V; Faure, P; Granon, S; Mameli-Engvall, M; Maubourguet, N | 1 |
| Caggiula, AR; Donny, EC; Liu, X; Palmatier, MI; Sved, AF | 1 |
| Bardo, MT; Bruntz, RC; Dwoskin, LP; Stairs, DJ; Zhu, J | 1 |
| Boyd, RT; Dávila-García, MI; Langley, R; Mishra, NC; Nandi, JS; Pena-Philippides, JC; Razani-Boroujerdi, S; Singh, SP; Sopori, ML | 1 |
| Davis, JA; Gould, TJ; Kenney, JW | 1 |
| Anderson, DJ; Bertrand, D; Bunnelle, W; Du, J; Gopalakrishnan, M; Marguerat, A; Surber, B; Surowy, C; Tribollet, E | 1 |
| Robles, N; Sabriá, J | 1 |
| Bencan, Z; Levin, ED | 1 |
| Bowlby, MR; Dunlop, J; Friis, S; Mathes, C; Sunesen, M | 1 |
| Hu, J; Jin, G; Liu, Q; Lucero, L; Lukas, RJ; Wu, J; Yang, K; Zhen, X; Zheng, C | 1 |
| Araki, H; Gomita, Y; Kitamura, Y; Sagara, H; Sendo, T; Shibata, K; Suemaru, K; Yae, T | 1 |
| Fu, XW; Lindstrom, J; Spindel, ER | 1 |
| Good, CH; Lupica, CR | 1 |
| Hotta, H; Kawashima, K; Uchida, S | 1 |
| Abdrakhmanova, GR; Baydyuk, M; Hernandez, S; Kellar, KJ; Xiao, Y | 1 |
| Brotherton, J; Cannady, R; Gotschlich, E; Kolia, N; Lau, E; Levin, ED; Wee, B; Weir, R | 1 |
| Thany, SH | 1 |
| Agrawal, R; Nath, C; Shukla, R; Tyagi, E | 1 |
| Crooks, PA; Dhawan, GK; Dwoskin, LP; Siripurapu, KB; Smith, AM; Zhang, Z | 1 |
| Camarasa, J; Escubedo, E; Pubill, D; Ratés, SG | 1 |
| Chang, A; Hernandez, C; Klann, E; Pautler, RG; Serrano, F; Sweatt, JD | 1 |
| Huang, LT; Lodge, D; Sherwood, JL; Sun, YJ; Wang, Y | 1 |
| Izumi, T; Ohmura, Y; Tsutsui-Kimura, I; Yamaguchi, T; Yoshida, T; Yoshioka, M | 1 |
| Gould, TJ; Raybuck, JD | 1 |
| Bardo, MT; Beckmann, JS; Crooks, PA; Denehy, ED; Dwoskin, LP; Horton, DB; Nickell, JR; Siripurapu, KB; Vartak, A | 1 |
| Gnegy, ME; Jutkiewicz, EM; Kim, MN; Zhang, M | 1 |
| Saeed Dar, M; Taslim, N | 1 |
| Feng, B; Guo, HJ; He, XS; Jia, D; Li, XQ; Liu, SB; Xing, JH; Zhao, MG | 1 |
| Buhlman, L; Jin, G; Khan, GM; Lukas, RJ; McIntosh, JM; Nichols, RA; Whiteaker, P; Wu, J; Yang, K | 1 |
| Besenfelder, S; Bugert, P; Klüter, H; Schedel, A; Thornton, S | 1 |
| Hahn, B; Shoaib, M; Stolerman, IP | 1 |
| Cook, D; Gardner, DR; Green, BT; Welch, KD | 1 |
| Moore, C; Ramage, AG; Wang, Y | 1 |
| Bell, KA; Chen, CK; McQuiston, AR; Shim, H | 1 |
| Bailey, CD; De Biasi, M; Lambe, EK; Picciotto, MR; Tian, MK | 1 |
| Gould, TJ; Kenney, JW; Raybuck, JD | 1 |
| DeCuir, D; Gordon, CJ; Kellar, KJ; Levin, ED; Rezvani, AH; Sexton, HG; Timofeeva, O; Xiao, Y | 1 |
| Nakauchi, S; Sumikawa, K | 1 |
| Chumley, P; Feng, W; Hua, P; Jaimes, EA; Rezonzew, G; Siegal, GP | 1 |
| Calixto, JB; Cola, M; Costa, R; Manjavachi, MN; Motta, EM | 1 |
| Chen, Y; Ge, D; Wang, J; Yuan, W; Zhou, X | 1 |
| Fletcher, PJ; Guy, EG | 1 |
| Christian, E; Ehrlichman, RS; Featherstone, RE; Halene, TB; Johnson, E; Leiser, SC; Lerman, C; Phillips, JM; Siegel, SJ; Thieu, T | 1 |
| Alkadhi, KA; Alzoubi, KH; Srivareerat, M; Tran, TT | 1 |
| Galarraga, E; Galindo-Charles, L; Garduño, J; Hernandez-Lopez, S; Jiménez-Rodríguez, J; Mihailescu, S; Tapia, D | 1 |
| Gardner, DR; Green, BT; Lima, FG; Pfister, JA; Welch, KD | 1 |
| Camarasa, J; Escubedo, E; Garcia-Ratés, S; Pubill, D | 1 |
| Cauley, M; Levin, ED; Rezvani, AH | 1 |
| Huang, YY; Kandel, DB; Kandel, ER; Levine, A | 1 |
| Drucker-Colin, R; Frías-Domínguez, C; Garduño, J; Hernández, S; Mihailescu, S | 1 |
| Liu, X | 1 |
| Danielson, K; Kivell, BM; Putt, F; Truman, P | 1 |
| Bernier, M; Moaddel, R; Paul, RK; Ramamoorthy, A; Singh, NS; Torjman, MC; Wainer, IW | 1 |
| Damaj, MI; De Biasi, M; Harenza, JL; Miles, MF; Muldoon, PP | 1 |
| Braida, D; Gotti, C; Martucci, R; Ponzoni, L; Sala, M; Sparatore, F | 1 |
| Kiguchi, N; Kishioka, S; Kobayashi, Y; Maeda, T; Ozaki, M; Saika, F; Ueno, K; Wakida, N; Yamamoto, C | 1 |
| Carter, CJ; Magoski, NS; White, SH | 1 |
| Baier, CJ; Barrantes, FJ; Bouzat, C; Caviedes, P; Dionisio, L; Franco, DL; Gallegos, CE; Mongiat, LA | 1 |
| Bernier, M; Green, CE; Khadeer, M; Moaddel, R; O'Loughlin, K; Paul, RK; Sanghvi, M; Singh, NS; Torjman, MC; Wainer, IW | 1 |
| Bregestovski, P; Chroni-Tzartou, D; Giastas, P; Tzartos, SJ; Zarkadas, E; Zouridakis, M | 1 |
| Cheng, Z; Jing-Lin, Z; Li-Sha, G; Wen-Wu, Z; Xing-Xing, C; Xue-Si, C; Yue-Chun, L | 1 |
| Cahuzac, ELM; Lewis, AS; Mineur, YS; Picciotto, MR; Smith, PH | 1 |
| Bardo, MT; Beckmann, JS; Crooks, PA; Dwoskin, LP; Horton, DB; McIntosh, JM; Meyer, AC; Pivavarchyk, M; Smith, AM; Wooters, TE; Zheng, G | 1 |
| Choe, ES; Choi, MJ; Lee, JY; Lee, YJ; Seo, JW; Yoon, SS | 1 |
| Akiyama, I; Hayashi, S; Kadowaki, M; Nakashima, A; Ono, Y; Osuga, Y; Saito, S; Shima, T; Ushijima, A; Yamada-Nomoto, K; Yoshino, O | 1 |
| Café-Mendes, CC; de Sá Lima, L; Ferreira, ZS; Garay-Malpartida, HM; Malta, MB; Marcourakis, T; Markus, RP; Scavone, C | 1 |
| de Moura, FB; McMahon, LR | 1 |
| Huang, SH; Jong, A; Li, L; Liu, L; Mao, DA; Wu, CH; Yu, J; Zhang, B | 1 |
| Abdollahi, AR; Dehpour, AR; Ejtemaei Mehr, S; Faghir-Ghanesefat, H; Mokhtari, T; Rahimi, N; Yarmohammadi, F | 1 |
| Chao, X; Cheng, Z; De-Pu, Z; Guang-Yi, C; Jia, L; Jia-Feng, L; Li-Sha, G; Maoping, C; Wen-Wu, Z; Xiaohong, G; Yue-Chun, L | 1 |
| Deben, D; Geyer, MA; Grim, A; Groenink, L; Higa, KK; Milienne-Petiot, M; Twamley, EW; Young, JW | 1 |
| Abbaszadeh-Kasbi, A; Afshari, K; Dehdashtian, A; Dehpour, AR; Haddadi, NS; Jazaeri, SZ; Khodaei, N; Momeni, M | 1 |
| Abd-Alhaseeb, MM; El-Gowilly, SM; El-Mas, MM; Fouda, MA; Sallam, MY | 1 |
| Kim, B; Kim, JW; Lim, CW; Park, S; Qi, J; Zhao, J; Zhou, Z | 1 |
| Fujigaki, H; Fujigaki, S; Hasegawa, M; Hirakawa, M; Hoshi, M; Kosuge, A; Kubota, H; Kunisawa, K; Kurahashi, H; Mori, Y; Mouri, A; Murakami, R; Nabeshima, T; Nakano, T; Niijima, M; Saito, K; Yamamoto, Y | 1 |
| Deyama, S; Esaki, H; Fukao, A; Ito, S; Izumi, S; Kaneda, K; Nishitani, N | 1 |
| Hayashi, S; Kadowaki, M; Kanauchi, Y; Lee, J; Yamamoto, T; Yoshida, M; Zhang, Y | 1 |
1 review(s) available for nicotine and methyllycaconitine
| Article | Year |
|---|---|
[Desensitizing function of calcium mobilized by the postsynaptic neuronal-type nicotinic acetylcholine receptors at the neuromuscular junction].
Topics: Aconitine; Animals; Calcium; Calcium Signaling; Choline; Excitatory Postsynaptic Potentials; Mice; Neuromuscular Junction; Nicotine; Receptors, Nicotinic | 1999 |
167 other study(ies) available for nicotine and methyllycaconitine
| Article | Year |
|---|---|
Methyllycaconitine and (+)-anatoxin-a differentiate between nicotinic receptors in vertebrate and invertebrate nervous systems.
Topics: Aconitine; Aconitum; Animals; Bacterial Toxins; Binding, Competitive; Brain; Bungarotoxins; Cyanobacteria Toxins; Ganglia; Grasshoppers; Kinetics; Marine Toxins; Microcystins; Nicotine; Rats; Receptors, Nicotinic; Species Specificity; Tropanes | 1988 |
Nicotine increases intracellular calcium in rat hippocampal neurons via voltage-gated calcium channels.
Topics: Aconitine; Alkaloids; Animals; Azocines; Calcium; Calcium Channels; Cells, Cultured; Dose-Response Relationship, Drug; Fura-2; Hippocampus; Membrane Potentials; Nicotine; Quinolizines; Rats; Rats, Inbred Strains; Time Factors | 1995 |
Nicotinic acetylcholine receptors in primary cultures of hippocampal neurons: pharmacology and Ca++ permeability.
Topics: Aconitine; Animals; Binding Sites; Bungarotoxins; Calcium; Cells, Cultured; Hippocampus; Kinetics; Neurons; Nicotine; Permeability; Potassium Chloride; Rats; Receptors, Nicotinic | 1994 |
Augmented responses to intrathecal nicotinic agonists in spontaneous hypertension.
Topics: Aconitine; Alkaloids; Animals; Azocines; Blood Pressure; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Injections, Spinal; Male; Mecamylamine; Motor Activity; Nicotine; Nicotinic Agonists; Quinolizines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spinal Cord; Stereotyped Behavior | 1994 |
Cardiovascular and behavioral responses to nicotinic agents administered intrathecally.
Topics: Aconitine; Alkaloids; Animals; Atropine; Azocines; Behavior, Animal; Blood Pressure; Bungarotoxins; Cardiovascular System; Dihydro-beta-Erythroidine; Ganglionic Stimulants; Heart Rate; Injections, Spinal; Lobeline; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Nociceptors; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Sensitivity and Specificity; Spinal Cord; Trimethaphan | 1994 |
Nicotinic acetylcholine receptors in separate brain regions exhibit different affinities for methyllycaconitine.
Topics: Aconitine; Animals; Brain; Bungarotoxins; Carbachol; Chick Embryo; Extracellular Space; Ganglia, Parasympathetic; In Vitro Techniques; Iodine Radioisotopes; Muscle, Skeletal; Nicotine; Radioligand Assay; Rats; Receptors, Nicotinic | 1996 |
Nicotine cue: lack of effect of the alpha 7 nicotinic receptor antagonist methyllycaconitine.
Topics: Aconitine; Animals; Conditioning, Operant; Cues; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic | 1996 |
Pharmacological characterization of a nicotinic autoreceptor in rat hippocampal synaptosomes.
Topics: Acetylcholine; Aconitine; Animals; Calcium; Choline; Dihydro-beta-Erythroidine; Hippocampus; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pempidine; Potassium Chloride; Rats; Receptors, Nicotinic; Synaptosomes | 1996 |
Role of Ca2+ ions in nicotinic facilitation of GABA release in mouse thalamus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Action Potentials; Alkaloids; Animals; Arousal; Atropine; Azocines; Bacterial Toxins; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channel Blockers; Calcium Channels; Carbachol; Cations, Divalent; Cyanobacteria Toxins; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; GABA Antagonists; gamma-Aminobutyric Acid; Ion Transport; Lobeline; Marine Toxins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcystins; Neurons, Afferent; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Potassium; Pyridazines; Pyridines; Quinolizines; Receptors, GABA-A; Receptors, Nicotinic; Tetrodotoxin; Thalamic Nuclei | 1997 |
Effects of nicotine on human nasal epithelium: evidence for nicotinic receptors in non-excitable cells.
Topics: Absorption; Aconitine; Amiloride; Calcium; Calcium Channel Blockers; Cells, Cultured; Extracellular Space; Humans; Intracellular Membranes; Nasal Mucosa; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Osmolar Concentration; Receptors, Nicotinic; Sodium; Tetrodotoxin; Verapamil | 1997 |
Activation of alpha7 nicotinic acetylcholine receptor promotes survival of spinal cord motoneurons.
Topics: Acetylcholine; Aconitine; Animals; Calcium; Cell Survival; Egtazic Acid; Motor Neurons; Nicotine; Rats; Receptors, Nicotinic; Spinal Cord | 1997 |
Nicotine protects cultured cortical neurons against glutamate-induced cytotoxicity via alpha7-neuronal receptors and neuronal CNS receptors.
Topics: Aconitine; Animals; Bungarotoxins; Cell Survival; Cells, Cultured; Cerebral Cortex; Cysteine; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; Glutamic Acid; Ionomycin; Ionophores; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Antagonists; Rats; Receptors, Nicotinic; S-Nitrosothiols; Toxins, Biological | 1997 |
Neuronal alpha-bungarotoxin receptors differ structurally from other nicotinic acetylcholine receptors.
Topics: Acetylcholine; Aconitine; Alkylation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Binding Sites; Bungarotoxins; Centrifugation, Density Gradient; Cholinergic Agents; Cross-Linking Reagents; Neoplasm Proteins; Nerve Tissue Proteins; Nicotine; Patch-Clamp Techniques; PC12 Cells; Rats; Receptors, Nicotinic; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Recombinant Fusion Proteins; Structure-Activity Relationship; Succinimides | 1997 |
Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Binding Sites; Bungarotoxins; Hippocampus; Mice; Mice, Knockout; Mice, Neurologic Mutants; Nerve Tissue Proteins; Nicotine; Rats; Receptors, Nicotinic; Sequence Deletion; Time Factors | 1997 |
Up-regulation of human alpha7 nicotinic receptors by chronic treatment with activator and antagonist ligands.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Benzylidene Compounds; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Dimethylphenylpiperazinium Iodide; Humans; Insecticides; Iodine Radioisotopes; Kidney; Kinetics; Ligands; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Receptors, Nicotinic; Transfection; Up-Regulation | 1998 |
Nicotine and food induced dopamine release in the nucleus accumbens of the rat: putative role of alpha7 nicotinic receptors in the ventral tegmental area.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Dopamine; Food; Microdialysis; Nerve Endings; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats; Receptors, Nicotinic; Ventral Tegmental Area | 1998 |
Synaptic potentials mediated via alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal interneurons.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Electrophysiology; Excitatory Postsynaptic Potentials; Hippocampus; Insecticides; Interneurons; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Synaptic Transmission | 1998 |
Nicotinic receptors in the rat prefrontal cortex: increase in glutamate release and facilitation of mediodorsal thalamo-cortical transmission.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Animals; Autoradiography; Cerebral Cortex; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Insecticides; Locomotion; Male; Mecamylamine; Microdialysis; Neural Pathways; Neurons, Afferent; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Reaction Time; Receptors, Nicotinic; Synaptic Transmission; Thalamus; Tritium | 1999 |
Gain of function mutation of the alpha7 nicotinic receptor: distinct pharmacology of the human alpha7V274T variant.
Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amino Acid Substitution; Animals; Atropine; Choline; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Genetic Variation; Humans; Lobeline; Mecamylamine; Membrane Potentials; Muscarinic Antagonists; Mutation; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oocytes; Pyridines; Pyrrolidines; Receptors, Nicotinic; Threonine; Tubocurarine; Valine; Xenopus | 1999 |
Inducible, heterologous expression of human alpha7-nicotinic acetylcholine receptors in a native nicotinic receptor-null human clonal line.
Topics: Acetylcholine; Aconitine; Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Azocines; Blotting, Northern; Bungarotoxins; Carbachol; Dimethylphenylpiperazinium Iodide; DNA, Complementary; Gene Expression; Humans; Insecticides; Iodine Radioisotopes; Neuroblastoma; Neurons; Nicotine; Nicotinic Agonists; Plasmids; Protein Synthesis Inhibitors; Quinolizines; Receptors, Nicotinic; Recombinant Proteins; RNA, Messenger; Tetracycline; Transfection; Tubocurarine; Tumor Cells, Cultured; Up-Regulation | 1999 |
Characterisation of the binding of [3H]methyllycaconitine: a new radioligand for labelling alpha 7-type neuronal nicotinic acetylcholine receptors.
Topics: Aconitine; Animals; Binding, Competitive; Brain; Bungarotoxins; Cell Membrane; Cholinergic Agents; Male; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 1999 |
Modulation of synaptic transmission by nicotine and nicotinic antagonists in hippocampus.
Topics: Aconitine; Animals; Dihydro-beta-Erythroidine; Hippocampus; In Vitro Techniques; Mecamylamine; Neural Inhibition; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1999 |
Action of ethanol on responses to nicotine from cerebellar interneurons and medial septal neurons: relationship to methyllycaconitine inhibition of nicotine responses.
Topics: Aconitine; Animals; Central Nervous System Depressants; Cerebellum; Ethanol; Interneurons; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Septal Nuclei | 1999 |
Action of ethanol on responses to nicotine from cerebellar Purkinje neurons: relationship to methyllycaconitine (MLA) inhibition of nicotine responses.
Topics: Aconitine; Animals; Bungarotoxins; Ethanol; Iontophoresis; Male; Nicotine; Nicotinic Antagonists; Purkinje Cells; Rats; Rats, Sprague-Dawley | 1999 |
Beta-estradiol attenuate amyloid beta-peptide toxicity via nicotinic receptors.
Topics: Aconitine; Amyloid beta-Peptides; Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cell Survival; Cholinesterase Inhibitors; Estradiol; Formazans; Humans; Mecamylamine; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; PC12 Cells; Pyridines; Rats; Receptors, Nicotinic; Tetrazolium Salts; Tumor Cells, Cultured | 1999 |
Striatal application of nicotine, but not of lobeline, attenuates dopamine release in freely moving rats.
Topics: Aconitine; Animals; Cocaine; Corpus Striatum; Dopamine; Kinetics; Lobeline; Male; Mecamylamine; Microdialysis; Nerve Endings; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2000 |
Nicotine reverses GABAergic inhibition of long-term potentiation induction in the hippocampal CA1 region.
Topics: Aconitine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Insecticides; Interneurons; Long-Term Potentiation; Muscimol; Neural Pathways; Nicotine; Nicotinic Agonists; Pyramidal Cells; Pyridines; Rats; Receptors, GABA-A; Receptors, Nicotinic | 2000 |
Characterisation of the effects of nicotine in the five-choice serial reaction time task in rats: antagonist studies.
Topics: Aconitine; Animals; Dihydro-beta-Erythroidine; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Reaction Time | 2000 |
Effects of methyllycaconitine (MLA), an alpha 7 nicotinic receptor antagonist, on nicotine- and cocaine-induced potentiation of brain stimulation reward.
Topics: Aconitine; Animals; Cocaine; Dopamine Uptake Inhibitors; Hypothalamic Area, Lateral; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reward; Ventral Tegmental Area | 2000 |
Amyloid peptide Abeta(1-42) binds selectively and with picomolar affinity to alpha7 nicotinic acetylcholine receptors.
Topics: Aconitine; Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Azocines; Binding, Competitive; Cerebral Cortex; Guinea Pigs; Hippocampus; Kinetics; Male; Nicotine; Peptide Fragments; Quinolizines; Radioligand Assay; Rats; Rats, Long-Evans; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Synaptic Membranes; Tritium | 2000 |
Nicotine-induced excitation of midbrain dopamine neurons in vitro involves ionotropic glutamate receptor activation.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Action Potentials; Animals; Dihydro-beta-Erythroidine; Dopamine; In Vitro Techniques; Insecticides; Mecamylamine; Neurons; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Ventral Tegmental Area | 2000 |
Calcium mobilization elicited by two types of nicotinic acetylcholine receptors in mouse substantia nigra pars compacta.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Action Potentials; Animals; Benzoates; Bungarotoxins; Calcium; Calcium Channel Blockers; Choline; Dihydro-beta-Erythroidine; Endoplasmic Reticulum; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Glycine; In Vitro Techniques; Indoles; Insecticides; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neurons; Nicotine; Nicotinic Agonists; Nifedipine; Nootropic Agents; Patch-Clamp Techniques; Polyamines; Presynaptic Terminals; Receptors, Nicotinic; Substantia Nigra; Tetrodotoxin; Tyrosine 3-Monooxygenase | 2000 |
Abnormal regulation of high affinity nicotinic receptors in subjects with schizophrenia.
Topics: Aconitine; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Animals; Antipsychotic Agents; Brain; Bridged Bicyclo Compounds, Heterocyclic; Child; Female; Haloperidol; Humans; Male; Middle Aged; Nicotine; Nicotinic Agonists; Pyridines; Rats; Receptors, Nicotinic; Regression Analysis; Schizophrenia; Smoking | 2000 |
Antagonism of the discriminative and aversive stimulus properties of nicotine in C57BL/6J mice.
Topics: Aconitine; Animals; Avoidance Learning; Behavior, Animal; Dihydro-beta-Erythroidine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Reinforcement, Psychology; Taste | 2000 |
The effect of nicotine and haloperidol co-treatment on nicotinic receptor levels in the rat brain.
Topics: Aconitine; Animals; Brain Chemistry; Bridged Bicyclo Compounds, Heterocyclic; Dopamine Antagonists; Haloperidol; Insecticides; Male; Nicotine; Nicotinic Agonists; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Muscarinic; Receptors, Nicotinic; Schizophrenia; Smoking; Spiperone; Tritium | 2001 |
Chronic exposure to nicotine upregulates the human (alpha)4((beta)2 nicotinic acetylcholine receptor function.
Topics: Acetylcholine; Aconitine; Cell Line; Dose-Response Relationship, Drug; Electrophysiology; Humans; Ion Channels; Kidney; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Protein Synthesis Inhibitors; Receptors, Nicotinic; Time Factors; Transfection; Up-Regulation | 2001 |
Nicotine accelerates reversal of long-term potentiation and enhances long-term depression in the rat hippocampal CA1 region.
Topics: Aconitine; Animals; Excitatory Postsynaptic Potentials; Hippocampus; Insecticides; Long-Term Potentiation; Membrane Potentials; Neuronal Plasticity; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley | 2001 |
Acute and chronic nicotine exposure reverse age-related declines in the induction of long-term potentiation in the rat hippocampus.
Topics: Aconitine; Aging; alpha7 Nicotinic Acetylcholine Receptor; Animals; Excitatory Postsynaptic Potentials; Hippocampus; Insecticides; Long-Term Potentiation; Membrane Potentials; Neuronal Plasticity; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2001 |
Heterogeneity of neuronal nicotinic acetylcholine receptors in 5-HT-containing chemoreceptor cells of the chicken aorta.
Topics: Acetylcholine; Aconitine; Algorithms; Animals; Aorta, Thoracic; Bungarotoxins; Chemoreceptor Cells; Chickens; Dimethylphenylpiperazinium Iodide; Epithelial Cells; Hexamethonium; Male; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Serotonin | 2001 |
Choline blocks AMPA-induced dark cell degeneration of Purkinje neurons: potential role of the alpha7 nicotinic receptor.
Topics: Aconitine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; alpha7 Nicotinic Acetylcholine Receptor; Animals; Choline; Excitatory Amino Acid Agonists; Extracellular Space; Female; Gluconates; Insecticides; Lidocaine; Male; Meglumine; Nerve Degeneration; Neurotoxins; Nicotine; Nootropic Agents; Organ Culture Techniques; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Nicotinic; Sodium; Sodium Channels; Sodium Chloride; Tetrodotoxin | 2001 |
Cotinine binding to nicotinic acetylcholine receptors in bovine chromaffin cell and rat brain membranes.
Topics: Aconitine; Animals; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cell Membrane; Chromaffin Cells; Cotinine; Frontal Lobe; Hippocampus; Male; Nicotine; Nicotinic Agonists; Pyridines; Rats; Rats, Wistar; Receptors, Nicotinic | 2001 |
Regulation of GABA release by nicotinic acetylcholine receptors in the neonatal rat hippocampus.
Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Animals, Newborn; Bicuculline; Bridged-Ring Compounds; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Insecticides; Membrane Potentials; Nicotine; Nicotinic Agonists; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Nicotinic; Spiro Compounds | 2001 |
Dorsal root ganglion neurons express multiple nicotinic acetylcholine receptor subtypes.
Topics: Acetylcholine; Aconitine; Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Animals; Azocines; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Cell Size; Cells, Cultured; DNA Primers; Electrophysiology; Ganglia, Spinal; Gene Expression; Insecticides; Neurons, Afferent; Nicotine; Nicotinic Agonists; Pyridines; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; RNA, Messenger; Vasodilator Agents | 2001 |
The nicotinic antagonist methyllycaconitine has differential effects on nicotine self-administration and nicotine withdrawal in the rat.
Topics: Aconitine; Animals; Behavior, Animal; Brain; Disease Models, Animal; Electric Stimulation; Electrodes, Implanted; Male; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Reward; Self Administration; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2001 |
Nicotine-induced phosphorylation of extracellular signal-regulated protein kinase and CREB in PC12h cells.
Topics: Aconitine; Animals; Benzylamines; Bungarotoxins; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Hexamethonium; Insecticides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nifedipine; PC12 Cells; Phosphorylation; Potassium; ras Proteins; Rats; Receptors, Nicotinic; Sulfonamides; Tubocurarine | 2001 |
Ventral hippocampal alpha 7 nicotinic receptor blockade and chronic nicotine effects on memory performance in the radial-arm maze.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Dose-Response Relationship, Drug; Female; Hippocampus; Insecticides; Maze Learning; Memory; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2001 |
Nicotine increases the expression of high affinity nerve growth factor receptors in both in vitro and in vivo.
Topics: Aconitine; Animals; Blotting, Western; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Antagonism; Hippocampus; Infusions, Intravenous; Male; Mecamylamine; Neurons; Nicotine; PC12 Cells; Rats; Rats, Wistar; Receptors, Nicotinic | 2002 |
Methyllycaconitine is a potent antagonist of alpha-conotoxin-MII-sensitive presynaptic nicotinic acetylcholine receptors in rat striatum.
Topics: Aconitine; Animals; Autoradiography; Binding, Competitive; Calcium Channel Blockers; Conotoxins; Dopamine; In Vitro Techniques; Male; Neostriatum; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Presynaptic; Synaptosomes | 2002 |
Alpha7-nicotinic acetylcholine receptors on cerebral perivascular sympathetic nerves mediate choline-induced nitrergic neurogenic vasodilation.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Basilar Artery; Calcium; Cells, Cultured; Cerebral Arteries; Choline; Electric Stimulation; Female; Ganglia, Parasympathetic; In Vitro Techniques; Male; Nicotine; Nitric Oxide; Nitroarginine; Potassium Chloride; Receptors, Nicotinic; Superior Cervical Ganglion; Swine; Sympathetic Nervous System; Tetrodotoxin; Vasodilation | 2002 |
Upregulation of [3H]methyllycaconitine binding sites following continuous infusion of nicotine, without changes of alpha7 or alpha6 subunit mRNA: an autoradiography and in situ hybridization study in rat brain.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Autoradiography; Binding Sites; Brain; In Situ Hybridization; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic; RNA, Messenger; Up-Regulation | 2002 |
The motivational valence of nicotine in the rat ventral tegmental area is switched from rewarding to aversive following blockade of the alpha7-subunit-containing nicotinic acetylcholine receptor.
Topics: 2-Amino-5-phosphonovalerate; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Conditioning, Operant; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Microinjections; Motivation; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Reinforcement, Psychology; Reward; Ventral Tegmental Area | 2003 |
Methyllycaconitine (MLA) blocks the nicotine evoked anxiogenic effect and 5-HT release in the dorsal hippocampus: possible role of alpha7 receptors.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anxiety; Behavior, Animal; Cholinergic Antagonists; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Interpersonal Relations; Male; Motor Activity; Nicotine; Nicotinic Antagonists; Random Allocation; Rats; Receptors, Nicotinic; Serotonin; Time Factors | 2003 |
Nicotine enhances the depressive actions of A beta 1-40 on long-term potentiation in the rat hippocampal CA1 region in vivo.
Topics: Aconitine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Electrophysiology; Hippocampus; Injections, Intraventricular; Long-Term Potentiation; Male; Neuronal Plasticity; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Peptide Fragments; Rats; Rats, Wistar; Receptors, Nicotinic | 2003 |
Functional properties of homomeric, human alpha 7-nicotinic acetylcholine receptors heterologously expressed in the SH-EP1 human epithelial cell line.
Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Bungarotoxins; Calcium; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Transfection | 2003 |
N-n-alkylpyridinium analogs, a novel class of nicotinic receptor antagonists: selective inhibition of nicotine-evoked [3H] dopamine overflow from superfused rat striatal slices.
Topics: Aconitine; Animals; Brain; Cell Membrane; Corpus Striatum; Dopamine; In Vitro Techniques; Nicotine; Nicotinic Antagonists; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Tritium | 2003 |
Do different mechanisms underlie two anxiogenic effects of systemic nicotine?
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anxiety; Behavior, Animal; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Piperazines; Pyridines; Rats; Receptor, Serotonin, 5-HT1A; Receptors, Nicotinic; Serotonin Antagonists; Social Behavior | 2003 |
Dual effects of nicotine on dopamine neurons mediated by different nicotinic receptor subtypes.
Topics: Aconitine; Action Potentials; Analysis of Variance; Animals; Brain; Dihydro-beta-Erythroidine; Dopamine; Dose-Response Relationship, Drug; Male; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oncogene Proteins v-fos; Protein Subunits; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Nicotinic | 2003 |
Nicotine recruits a local glutamatergic circuit to excite septohippocampal GABAergic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Acyclovir; Animals; Animals, Newborn; Atropine; Bicuculline; Bungarotoxins; Carrier Proteins; Cell Count; Choline; Chromones; Cycloleucine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Electric Conductivity; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Membrane Transport Proteins; Microscopy, Electron; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Parvalbumins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Resorcinols; Septum of Brain; Synapses; Tetrodotoxin; Tubocurarine; Valine; Vesicular Glutamate Transport Protein 2; Vesicular Transport Proteins | 2003 |
Carbamoylcholine homologs: novel and potent agonists at neuronal nicotinic acetylcholine receptors.
Topics: Aconitine; Animals; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Carbachol; Cells, Cultured; Humans; N-Methylscopolamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Parasympatholytics; Pyridines; Rats; Receptors, Nicotinic; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Tritium | 2003 |
Functional expression and properties of a nicotinic alpha9/5-HT3A chimeric receptor.
Topics: Aconitine; Animals; Atropine; DNA, Complementary; Membrane Potentials; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oocytes; Patch-Clamp Techniques; Rats; Receptors, Nicotinic; Receptors, Serotonin, 5-HT3; Recombinant Fusion Proteins; Serotonin Antagonists; Strychnine; Xenopus laevis | 2003 |
Nicotinic acetylcholinergic receptors regulate the intraspinal release of acetylcholine in male rats.
Topics: Acetylcholine; Aconitine; Animals; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Male; Mecamylamine; Microdialysis; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Spinal Cord; Time Factors | 2003 |
Protective effects of nicotine on ethanol-induced toxicity in cultured cerebellar granule cells.
Topics: Aconitine; Animals; Cells, Cultured; Central Nervous System Depressants; Cerebellum; Culture Media; Dihydro-beta-Erythroidine; Ethanol; Female; L-Lactate Dehydrogenase; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2003 |
Endogenous ouabain-like factor (OLF) secretion is modulated by nicotinic mechanisms in rat adrenocortical cells.
Topics: Acetylcholine; Aconitine; Adrenal Cortex; Animals; Cardenolides; Digoxin; Dose-Response Relationship, Drug; Drug Synergism; Hexamethonium; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Physostigmine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Saponins | 2004 |
Nicotine improves sustained attention in mice: evidence for involvement of the alpha7 nicotinic acetylcholine receptor.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Attention; Conditioning, Operant; Genotype; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Psychomotor Performance; Radioligand Assay; Reaction Time; Receptors, Nicotinic; Synaptic Membranes; Synaptosomes | 2004 |
Nicotinic acetylcholine receptor alpha7 subunit mediates migration of vascular smooth muscle cells toward nicotine.
Topics: Aconitine; Actins; alpha7 Nicotinic Acetylcholine Receptor; Animals; Basilar Artery; Cell Line; Chemotaxis; Cytoskeleton; Down-Regulation; Forecasting; Guinea Pigs; Muscle, Smooth, Vascular; Myosin-Light-Chain Kinase; Nicotine; Phosphorylation; Pseudopodia; Receptors, Nicotinic; Stereoisomerism | 2004 |
Development of subtype-selective ligands as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release.
Topics: Aconitine; Animals; Binding Sites; Binding, Competitive; Brain; Choline; Dopamine; Ligands; Male; Molecular Structure; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Structure-Activity Relationship | 2004 |
(-)-nicotine ameliorates corticosterone's potentiation of N-methyl-d-aspartate receptor-mediated cornu ammonis 1 toxicity.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Cell Survival; Corticosterone; Disease Models, Animal; Drug Interactions; Hippocampus; In Vitro Techniques; Male; Mifepristone; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic | 2004 |
Lobeline analogs with enhanced affinity and selectivity for plasmalemma and vesicular monoamine transporters.
Topics: Aconitine; Animals; Biological Transport; Carrier Proteins; Cells, Cultured; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ganglionic Stimulants; Humans; Iodine Radioisotopes; Kinetics; Lobeline; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuropeptides; Nicotine; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Rubidium; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters; Tetrabenazine; Tritium; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2004 |
Involvement of alpha7- and alpha4beta2-type postsynaptic nicotinic acetylcholine receptors in nicotine-induced excitation of dopaminergic neurons in the substantia nigra: a patch clamp and single-cell PCR study using acutely dissociated nigral neurons.
Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Atropine; Cells, Cultured; Dihydro-beta-Erythroidine; Dopamine; Muscarinic Antagonists; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Polymerase Chain Reaction; Rats; Rats, Wistar; Receptors, Nicotinic; Substantia Nigra | 2004 |
Nicotine and epibatidine triggered prolonged rise in calcium and TH gene transcription in PC12 cells.
Topics: Aconitine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Calcium; Dideoxyadenosine; Dose-Response Relationship, Drug; Egtazic Acid; Luciferases; Nicotine; PC12 Cells; Promoter Regions, Genetic; Pyridines; Rats; Recombinant Fusion Proteins; Time Factors; Transcription, Genetic; Tyrosine 3-Monooxygenase | 2004 |
Role of alpha7-nicotinic acetylcholine receptors in tetanic stimulation-induced gamma oscillations in rat hippocampal slices.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Animals, Newborn; Bicuculline; Biological Clocks; Bungarotoxins; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Electrophysiology; GABA Antagonists; Hippocampus; In Vitro Techniques; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic; Spectrum Analysis; Time Factors | 2005 |
Time and brain region specific up-regulation of low affinity neuronal nicotinic receptors during chronic nicotine administration in mice.
Topics: Aconitine; Animals; Binding Sites; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebral Cortex; Corpus Striatum; Hippocampus; Male; Mesencephalon; Mice; Mice, Inbred Strains; Neurons; Nicotine; Nicotinic Agonists; Pyridines; Radioligand Assay; Receptors, Nicotinic; Time Factors; Tritium; Up-Regulation | 2005 |
Chronic nicotine exposure alters blood-brain barrier permeability and diminishes brain uptake of methyllycaconitine.
Topics: Aconitine; Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Drug Administration Schedule; Infusion Pumps, Implantable; Male; Nicotine; Rats; Rats, Inbred F344 | 2005 |
The effects of DHBE and MLA on nicotine-induced enhancement of contextual fear conditioning in C57BL/6 mice.
Topics: Aconitine; Animals; Association Learning; Brain; Conditioning, Classical; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electroshock; Fear; Male; Mice; Nicotine; Receptors, Nicotinic | 2006 |
The effects of cholinergic and dopaminergic antagonists on nicotine-induced cerebral neurotransmitter changes.
Topics: Aconitine; Animals; Atropine; Benzazepines; Brain Chemistry; Cerebral Cortex; Dopamine; Dopamine Antagonists; Hippocampus; Male; Microdialysis; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Norepinephrine; Parasympatholytics; Rats; Rats, Sprague-Dawley; Salicylamides; Serotonin | 2005 |
Effects of alpha4beta2 and alpha7 nicotinic acetylcholine receptor antagonists on place aversion induced by naloxone in single-dose morphine-treated rats.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Conditioning, Operant; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2005 |
Nicotine-induced switch in the nicotinic cholinergic mechanisms of facilitation of long-term potentiation induction.
Topics: Acetylcholinesterase; Aconitine; Animals; Animals, Newborn; Antibodies, Monoclonal; Cholinergic Fibers; Denervation; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; Immunotoxins; In Vitro Techniques; Long-Term Potentiation; N-Glycosyl Hydrolases; Neural Inhibition; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Propanolamines; Quinoxalines; Rats; Receptors, Nicotinic; Ribosome Inactivating Proteins, Type 1; Saporins; Valine | 2005 |
Unequal neuroprotection afforded by the acetylcholinesterase inhibitors galantamine, donepezil, and rivastigmine in SH-SY5Y neuroblastoma cells: role of nicotinic receptors.
Topics: Aconitine; Amyloid beta-Peptides; Apoptosis; Benzopyrans; Cell Culture Techniques; Cell Line, Tumor; Cholinesterase Inhibitors; Chromones; Donepezil; Dose-Response Relationship, Drug; Enzyme Inhibitors; Galantamine; Humans; Indans; L-Lactate Dehydrogenase; Morpholines; Neuroblastoma; Neuroprotective Agents; Nicotine; Nitriles; Okadaic Acid; Phenylcarbamates; Phosphatidylinositol 3-Kinases; Piperidines; Proto-Oncogene Proteins c-bcl-2; Receptors, Nicotinic; Rivastigmine | 2005 |
Introduction of unsaturation into the N-n-alkyl chain of the nicotinic receptor antagonists, NONI and NDNI: effect on affinity and selectivity.
Topics: Aconitine; Animals; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Design; Drug Evaluation, Preclinical; Electric Stimulation; Humans; Male; Molecular Structure; Nicotine; Nicotinic Antagonists; Nomifensine; Protein Binding; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reward; Rubidium; Structure-Activity Relationship; Synaptosomes | 2005 |
Nicotinic modulation of glutamatergic synaptic transmission in region CA3 of the hippocampus.
Topics: Aconitine; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamates; Hippocampus; In Vitro Techniques; Male; Mecamylamine; Neurons, Afferent; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Synaptic Transmission | 2005 |
Desensitization of neuronal nicotinic receptors of human neuroblastoma SH-SY5Y cells during short or long exposure to nicotine.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Cell Line, Tumor; Conotoxins; Dose-Response Relationship, Drug; Humans; Kinetics; Membrane Potentials; Neuroblastoma; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Up-Regulation | 2005 |
Effect of amyloid peptides on the increase in TrkA receptor expression induced by nicotine in vitro and in vivo.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Brain; Bungarotoxins; Dose-Response Relationship, Drug; Male; Nerve Growth Factor; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; PC12 Cells; Peptide Fragments; Rats; Rats, Wistar; Receptor, trkA; Receptors, Nicotinic | 2005 |
Reparatory effects of nicotine on NMDA receptor-mediated synaptic plasticity in the hippocampal CA1 region of chronically lead-exposed rats.
Topics: Aconitine; Animals; Central Nervous System Stimulants; Child; Dihydro-beta-Erythroidine; Female; Hippocampus; Humans; Lead Poisoning, Nervous System; Long-Term Potentiation; Male; Neuronal Plasticity; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pentanoic Acids; Picrotoxin; Random Allocation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Synaptic Transmission | 2006 |
Nicotine reverses consolidated long-term potentiation in the hippocampal CA1 region.
Topics: Aconitine; Analysis of Variance; Animals; Dihydro-beta-Erythroidine; Dose-Response Relationship, Radiation; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Ethers, Cyclic; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Okadaic Acid; Oxazoles; Rats; Rats, Sprague-Dawley | 2006 |
Untranslated region-dependent exclusive expression of high-sensitivity subforms of alpha4beta2 and alpha3beta2 nicotinic acetylcholine receptors.
Topics: 5' Untranslated Regions; Acetylcholine; Aconitine; Animals; Chlorisondamine; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Estradiol; Female; Ferrets; Gene Expression; Membrane Potentials; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oocytes; Protein Isoforms; Protein Subunits; Receptors, Nicotinic; Tubocurarine; Xenopus laevis | 2006 |
Ventral hippocampal alpha7 and alpha4beta2 nicotinic receptor blockade and clozapine effects on memory in female rats.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Antipsychotic Agents; Clozapine; Dihydro-beta-Erythroidine; Female; Hippocampus; Maze Learning; Memory; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2006 |
Evaluation of the role of nicotinic acetylcholine receptor subtypes and cannabinoid system in the discriminative stimulus effects of nicotine in rats.
Topics: Aconitine; Animals; Arachidonic Acids; Azetidines; Benzamides; Benzoxazines; Camphanes; Cannabinoid Receptor Antagonists; Carbamates; Cyclohexanols; Dihydro-beta-Erythroidine; Discrimination Learning; Dose-Response Relationship, Drug; Drug Synergism; Endocannabinoids; Male; Mecamylamine; Morpholines; Naphthalenes; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Polyunsaturated Alkamides; Pyrazoles; Pyridines; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Nicotinic | 2006 |
Nicotine regulates SH-SY5Y neuroblastoma cell proliferation through the release of brain-derived neurotrophic factor.
Topics: Aconitine; Antibodies; Brain-Derived Neurotrophic Factor; Carbazoles; Carbon Isotopes; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Indole Alkaloids; Mecamylamine; Neuroblastoma; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptor, trkB; Thymidine; Time Factors | 2006 |
Contribution of valine 7' of TMD2 to gating of neuronal alpha3 receptor subtypes.
Topics: Acetylcholine; Aconitine; Animals; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Ion Channel Gating; Membrane Potentials; Mutagenesis; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Rats; Receptors, Nicotinic; Time Factors; Valine; Xenopus laevis | 2006 |
Synthesis, nicotinic acetylcholine receptor binding, antinociceptive and seizure properties of methyllycaconitine analogs.
Topics: Aconitine; Analgesics; Animals; Anticonvulsants; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Data Interpretation, Statistical; In Vitro Techniques; Indicators and Reagents; Male; Mice; Mice, Inbred ICR; Nicotine; Nicotinic Agonists; Pain Measurement; Pyridines; Rats; Reaction Time; Receptors, Nicotinic; Seizures | 2007 |
Long-term effects of chronic nicotine exposure on brain nicotinic receptors.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Brain; Mice; Mice, Inbred C57BL; Nicotine; Receptors, Nicotinic; Ventral Tegmental Area | 2007 |
Reinforcement enhancing effect of nicotine and its attenuation by nicotinic antagonists in rats.
Topics: Aconitine; Analysis of Variance; Animals; Conditioning, Operant; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Infusion Pumps; Infusions, Intravenous; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Photic Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reinforcement Schedule; Reinforcement, Psychology; Visual Perception | 2007 |
Individual differences in response to novelty predict prefrontal cortex dopamine transporter function and cell surface expression.
Topics: Aconitine; Animals; Behavior, Animal; Binding, Competitive; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Exploratory Behavior; Male; Motor Activity; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phenotype; Prefrontal Cortex; Presynaptic Terminals; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Synaptosomes; Tobacco Use Disorder | 2007 |
T cells express alpha7-nicotinic acetylcholine receptor subunits that require a functional TCR and leukocyte-specific protein tyrosine kinase for nicotine-induced Ca2+ response.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Calcium; CD3 Complex; Cell Membrane; Humans; Immunoprecipitation; Jurkat Cells; Leukocytes; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Neurons; Nicotine; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fyn; Pyridines; Rats; Receptors, Antigen, T-Cell; Receptors, Nicotinic; RNA, Small Interfering; T-Lymphocytes | 2007 |
Hippocampal alpha4beta2 nicotinic acetylcholine receptor involvement in the enhancing effect of acute nicotine on contextual fear conditioning.
Topics: Aconitine; Analysis of Variance; Animals; Behavior, Animal; Conditioning, Classical; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Interactions; Fear; Female; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic | 2007 |
[3H]A-585539 [(1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo[2.2.1]heptane], a novel high-affinity alpha7 neuronal nicotinic receptor agonist: radioligand binding characterization to rat and human brain.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Bungarotoxins; Cell Line; Humans; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Spiro Compounds | 2008 |
Effects of moderate chronic ethanol consumption on hippocampal nicotinic receptors and associative learning.
Topics: Aconitine; Alcoholism; Animals; Association Learning; Central Nervous System Depressants; Ethanol; Hippocampus; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic; Tritium | 2008 |
The role of alpha7 and alpha4beta2 nicotinic receptors in the nicotine-induced anxiolytic effect in zebrafish.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Dihydro-beta-Erythroidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Immobility Response, Tonic; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Swimming; Zebrafish; Zebrafish Proteins | 2008 |
Characterization of compounds on nicotinic acetylcholine receptor alpha7 channels using higher throughput electrophysiology.
Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Area Under Curve; Cell Line, Transformed; Cholinergic Agents; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Isoxazoles; Membrane Potentials; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Phenylurea Compounds; Rats; Receptors, Nicotinic | 2009 |
Distinctive nicotinic acetylcholine receptor functional phenotypes of rat ventral tegmental area dopaminergic neurons.
Topics: Acetylcholine; Aconitine; Action Potentials; Alkaloids; Animals; Azocines; Brain; Choline; Dihydro-beta-Erythroidine; Dopamine; Dose-Response Relationship, Drug; Gene Expression; Kinetics; Mecamylamine; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Protein Subunits; Quinolizines; Rats; Rats, Wistar; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2009 |
Nicotinic acetylcholine alpha4beta2 receptor regulates the motivational effect of intracranial self stimulation behavior in the runway method.
Topics: Aconitine; Animals; Behavior, Animal; Conditioning, Operant; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electric Stimulation; Male; Medial Forebrain Bundle; Motivation; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic; Reward; Running; Self Stimulation | 2008 |
Nicotine activates and up-regulates nicotinic acetylcholine receptors in bronchial epithelial cells.
Topics: Acetylcholine; Aconitine; Age Factors; alpha7 Nicotinic Acetylcholine Receptor; Animals; Autocrine Communication; Bronchi; Cells, Cultured; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Genistein; Gestational Age; Lung; Macaca mulatta; Mecamylamine; Membrane Potentials; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phosphorylation; Protein Kinase Inhibitors; Protein Tyrosine Phosphatases; Receptors, Nicotinic; Up-Regulation; Vanadates | 2009 |
Properties of distinct ventral tegmental area synapses activated via pedunculopontine or ventral tegmental area stimulation in vitro.
Topics: Aconitine; Afferent Pathways; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bicuculline; Dihydro-beta-Erythroidine; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Pedunculopontine Tegmental Nucleus; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Nicotinic; Strontium; Synapses; Synaptic Transmission; Ventral Tegmental Area | 2009 |
Long-term nicotine treatment reduces cerebral cortical vasodilation mediated by alpha4beta2-like nicotinic acetylcholine receptors in rats.
Topics: Aconitine; Animals; Cerebral Cortex; Cerebrovascular Circulation; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Male; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic; Regional Blood Flow; Time Factors; Vasodilation | 2009 |
Rat neuronal nicotinic acetylcholine receptors containing alpha7 subunit: pharmacological properties of ligand binding and function.
Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Cell Line; Cerebral Cortex; Gene Expression; Hippocampus; Humans; Inhibitory Concentration 50; Ligands; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Protein Binding; Rats; Receptors, Nicotinic | 2009 |
Nicotinic antagonist effects in the mediodorsal thalamic nucleus: regional heterogeneity of nicotinic receptor involvement in cognitive function.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Antipsychotic Agents; Clozapine; Cognition; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Maze Learning; Mediodorsal Thalamic Nucleus; Memory; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2009 |
Agonist actions of clothianidin on synaptic and extrasynaptic nicotinic acetylcholine receptors expressed on cockroach sixth abdominal ganglion.
Topics: Acetylcholine; Aconitine; Analysis of Variance; Animals; Biophysics; Cockroaches; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Postsynaptic Potentials; Ganglia, Invertebrate; Gene Expression Regulation; Guanidines; Male; Neonicotinoids; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Receptors, Nicotinic; Synapses; Thiazoles | 2009 |
Inhibitory role of cholinergic system mediated via alpha7 nicotinic acetylcholine receptor in LPS-induced neuro-inflammation.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Brain; Cytokines; Dihydro-beta-Erythroidine; Encephalitis; Gene Expression Regulation; Inflammation Mediators; Lipopolysaccharides; Neuroimmunomodulation; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oxotremorine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2010 |
The novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), inhibits nicotine-evoked [(3)H]norepinephrine overflow from rat hippocampal slices.
Topics: Aconitine; Allosteric Regulation; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Norepinephrine; Picolines; Rats; Rats, Sprague-Dawley; Tritium | 2009 |
The involvement of nicotinic receptor subtypes in the locomotor activity and analgesia induced by methamphetamine in mice.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; Dihydro-beta-Erythroidine; Drug Administration Schedule; Drug Interactions; Male; Methamphetamine; Mice; Motor Activity; Nicotine; Receptors, Nicotinic | 2009 |
NADPH oxidase mediates beta-amyloid peptide-induced activation of ERK in hippocampal organotypic cultures.
Topics: Acetophenones; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Hippocampus; NADPH Oxidases; Nicotine; Onium Compounds; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2009 |
Activation of presynaptic alpha7 nicotinic receptors evokes an excitatory response in hippocampal CA3 neurones in anaesthetized rats: an in vivo iontophoretic study.
Topics: 2-Amino-5-phosphonovalerate; Aconitine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; D-Aspartic Acid; Glutamic Acid; Hippocampus; Male; N-Methylaspartate; Neurons; Nicotine; Nicotinic Antagonists; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Presynaptic; Spiro Compounds | 2010 |
Endogenous acetylcholine modulates impulsive action via alpha4beta2 nicotinic acetylcholine receptors in rats.
Topics: Acetylcholine; Aconitine; Animals; Behavior, Animal; Choice Behavior; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Impulsive Behavior; Male; Nicotine; Rats; Rats, Wistar; Reaction Time; Receptors, Nicotinic | 2010 |
The role of nicotinic acetylcholine receptors in the medial prefrontal cortex and hippocampus in trace fear conditioning.
Topics: Aconitine; Analysis of Variance; Animals; Conditioning, Classical; Dihydro-beta-Erythroidine; Fear; Freezing Reaction, Cataleptic; Hippocampus; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex; Receptors, Nicotinic | 2010 |
The novel pyrrolidine nor-lobelane analog UKCP-110 [cis-2,5-di-(2-phenethyl)-pyrrolidine hydrochloride] inhibits VMAT2 function, methamphetamine-evoked dopamine release, and methamphetamine self-administration in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aconitine; Amphetamine-Related Disorders; Animals; Behavior, Animal; Cell Membrane; Conditioning, Operant; Corpus Striatum; Dopamine; Drug Tolerance; Lobeline; Male; Methamphetamine; Nicotine; Protein Binding; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reinforcement, Psychology; Self Administration; Synaptic Vesicles; Tetrabenazine; Vesicular Monoamine Transport Proteins | 2010 |
The sensitizing effect of acute nicotine on amphetamine-stimulated behavior and dopamine efflux requires activation of β2 subunit-containing nicotinic acetylcholine receptors and glutamate N-methyl-D-aspartate receptors.
Topics: Aconitine; Amphetamine; Animals; Behavior, Animal; Benzazepines; Central Nervous System Stimulants; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Female; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Varenicline | 2011 |
The role of nicotinic acetylcholine receptor (nAChR) α7 subtype in the functional interaction between nicotine and ethanol in mouse cerebellum.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Ataxia; Benzamides; Bridged Bicyclo Compounds; Cerebellum; Dose-Response Relationship, Drug; Ethanol; Infusions, Intraventricular; Male; Mice; Nicotine; Receptors, Nicotinic | 2011 |
Blocking α4β2 and α7 nicotinic acetylcholine receptors inhibits the reinstatement of morphine-induced CPP by drug priming in mice.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Cholinergic Antagonists; Conditioning, Operant; Dihydro-beta-Erythroidine; Drug Interactions; Extinction, Psychological; Male; Mice; Mice, Inbred BALB C; Morphine; Motor Activity; Narcotics; Nicotine; Nicotinic Agonists; Reaction Time; Receptors, Nicotinic; Reinforcement, Psychology; Time Factors | 2011 |
Functional nicotinic acetylcholine receptors containing α6 subunits are on GABAergic neuronal boutons adherent to ventral tegmental area dopamine neurons.
Topics: 4-Aminopyridine; Acetylcholine; Aconitine; Animals; Animals, Newborn; Bungarotoxins; Calcium; Conotoxins; Dihydro-beta-Erythroidine; Dopamine; Drug Interactions; Excitatory Amino Acid Agents; Female; GABA Agents; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Knockout; Neurons; Nicotine; Nicotinic Antagonists; Potassium Channel Blockers; Presynaptic Terminals; Protein Binding; Rats; Rats, Wistar; Receptors, Nicotinic; Synaptosomes; Ventral Tegmental Area | 2011 |
Cholinergic drugs inhibit in vitro megakaryopoiesis via the alpha7-nicotinic acetylcholine receptor.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Blotting, Western; Cell Differentiation; Cell Line; Cholinergic Agents; Down-Regulation; Flow Cytometry; Gene Expression Regulation; Humans; Integrin beta3; Megakaryocyte Progenitor Cells; Nicotine; Nicotinic Antagonists; Phorbol Esters; Platelet Membrane Glycoprotein IIb; Polymerase Chain Reaction; Receptors, Nicotinic; RNA, Messenger; Signal Transduction; Thrombopoiesis | 2011 |
Selective nicotinic receptor antagonists: effects on attention and nicotine-induced attentional enhancement.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Attention; Behavior, Animal; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Interactions; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Inbred Strains; Receptors, Nicotinic | 2011 |
Potentiation of the actions of acetylcholine, epibatidine, and nicotine by methyllycaconitine at fetal muscle-type nicotinic acetylcholine receptors.
Topics: Acetylcholine; Aconitine; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cholinesterase Inhibitors; Diterpenes; Drug Synergism; Fetus; Humans; Ligands; Membrane Potentials; Muscles; Neostigmine; Nicotine; Nicotinic Agonists; Pyridines; Receptors, Nicotinic; Structure-Activity Relationship | 2011 |
Nicotine's central cardiovascular actions: receptor subtypes involved and their possible physiological role in anaesthetized rats.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Anesthesia; Animals; Antidiuretic Hormone Receptor Antagonists; Cardiovascular System; Dihydro-beta-Erythroidine; Male; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2011 |
Nicotinic excitatory postsynaptic potentials in hippocampal CA1 interneurons are predominantly mediated by nicotinic receptors that contain α4 and β2 subunits.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Aconitine; Animals; Biophysics; CA1 Region, Hippocampal; Channelrhodopsins; Cholinergic Fibers; Diagonal Band of Broca; Dihydro-beta-Erythroidine; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Interneurons; Light; Mice; Neural Pathways; Nicotine; Nicotinic Antagonists; Optics and Photonics; Patch-Clamp Techniques; Quinoxalines; Receptors, Nicotinic; Transduction, Genetic; Voltage-Sensitive Dye Imaging | 2011 |
Plasticity of prefrontal attention circuitry: upregulated muscarinic excitability in response to decreased nicotinic signaling following deletion of α5 or β2 subunits.
Topics: Acetylcholine; Aconitine; Age Factors; Analysis of Variance; Animals; Atropine; Dihydro-beta-Erythroidine; Intracellular Signaling Peptides and Proteins; Male; Membrane Potentials; Mice; Mice, Knockout; Neuronal Plasticity; Neurons; Neuropeptides; Neurotransmitter Agents; Nicotine; Nicotinic Antagonists; Orexins; Patch-Clamp Techniques; Prefrontal Cortex; Receptors, Muscarinic; Receptors, Nicotinic; Signal Transduction; Up-Regulation | 2011 |
Nicotinic receptors in the dorsal and ventral hippocampus differentially modulate contextual fear conditioning.
Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Conditioning, Psychological; Cues; Fear; Hippocampus; Injections, Intraventricular; Male; Maze Learning; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Antagonists; Receptors, Nicotinic | 2012 |
Effects of sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, on body temperature regulation in mice and rats.
Topics: Aconitine; Animals; Azetidines; Body Temperature Regulation; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Nicotine; Nicotinic Antagonists; Pyridines; Rats; Receptors, Nicotinic | 2012 |
Endogenously released ACh and exogenous nicotine differentially facilitate long-term potentiation induction in the hippocampal CA1 region of mice.
Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Animals, Newborn; Biophysics; CA1 Region, Hippocampal; Dihydro-beta-Erythroidine; Electric Stimulation; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Receptors, Nicotinic; Synaptic Potentials | 2012 |
Nicotine exposure and the progression of chronic kidney disease: role of the α7-nicotinic acetylcholine receptor.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Blood Pressure; Chronic Disease; Disease Models, Animal; Disease Progression; Kidney Diseases; Male; NADPH Oxidase 4; NADPH Oxidases; Nephrectomy; Nicotine; Nicotinic Antagonists; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Transforming Growth Factor beta | 2012 |
Activation of the alpha-7 nicotinic acetylcholine receptor (α7 nAchR) reverses referred mechanical hyperalgesia induced by colonic inflammation in mice.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; Behavior, Animal; Benzamides; Bridged Bicyclo Compounds; Colitis; Dose-Response Relationship, Drug; Drug Antagonism; Hyperalgesia; Male; Mice; Mice, Inbred Strains; Molecular Targeted Therapy; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pain Threshold; Pain, Referred; Random Allocation; Receptors, Nicotinic | 2012 |
Nicotine enhances both excitatory and inhibitory synaptic inputs to inspiratory-activated airway vagal preganglionic neurons.
Topics: Acetylcholine; Aconitine; Animals; Animals, Newborn; Dihydro-beta-Erythroidine; Excitatory Postsynaptic Potentials; Glycine; Neostigmine; Neurons; Nicotine; Patch-Clamp Techniques; Rats; Receptors, Nicotinic; Vagus Nerve | 2013 |
Nicotine-induced enhancement of responding for conditioned reinforcement in rats: role of prior nicotine exposure and α4β2 nicotinic receptors.
Topics: Aconitine; Animals; Conditioning, Operant; Dihydro-beta-Erythroidine; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Long-Evans; Receptors, Nicotinic; Reinforcement Schedule | 2013 |
Nicotine receptor subtype-specific effects on auditory evoked oscillations and potentials.
Topics: Aconitine; Animals; Calcium Signaling; Event-Related Potentials, P300; Evoked Potentials, Auditory; Humans; Male; Mice; Nicotine; Nicotinic Antagonists; Receptors, Nicotinic | 2012 |
Role of α7- and α4β2-nAChRs in the neuroprotective effect of nicotine in stress-induced impairment of hippocampus-dependent memory.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Dihydro-beta-Erythroidine; Disease Models, Animal; Drug Delivery Systems; Hippocampus; Male; Maze Learning; Memory Disorders; Neuroprotective Agents; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic; Stress, Psychological; Time Factors | 2013 |
Presynaptic α4β2 nicotinic acetylcholine receptors increase glutamate release and serotonin neuron excitability in the dorsal raphe nucleus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Aconitine; Animals; Animals, Newborn; Atropine; Bicuculline; Cadmium Chloride; Chelating Agents; Cholinergic Agonists; Dihydro-beta-Erythroidine; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Indoles; Male; Muscarinic Antagonists; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Physostigmine; Presynaptic Terminals; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Nicotinic; Ryanodine; Serotonergic Neurons; Serotonin; Sodium Channel Blockers; Tetrodotoxin | 2012 |
Effect of α₇ nicotinic acetylcholine receptor agonists and antagonists on motor function in mice.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Animals; Diterpenes; Male; Mice; Motor Activity; Muscle, Skeletal; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic | 2013 |
3,4-Methylenedioxy-methamphetamine induces in vivo regional up-regulation of central nicotinic receptors in rats and potentiates the regulatory effects of nicotine on these receptors.
Topics: Aconitine; Animals; Blotting, Western; Brain; Bridged Bicyclo Compounds, Heterocyclic; Drug Administration Schedule; Drug Synergism; Immunoprecipitation; Injections, Subcutaneous; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nicotine; Nicotinic Agonists; Paroxetine; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Serotonin Plasma Membrane Transport Proteins; Time Factors; Up-Regulation | 2013 |
Improvement of attentional function with antagonism of nicotinic receptors in female rats.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Attention; Attention Deficit Disorder with Hyperactivity; Dihydro-beta-Erythroidine; Dizocilpine Maleate; Female; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2013 |
Nicotine primes the effect of cocaine on the induction of LTP in the amygdala.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amygdala; Animals; Bridged-Ring Compounds; Cocaine; Dihydro-beta-Erythroidine; Dopamine Uptake Inhibitors; Drug Synergism; Histone Deacetylase Inhibitors; Hydroxamic Acids; Long-Term Potentiation; Male; Mice; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Spiro Compounds; Time Factors; Vorinostat | 2013 |
Flattening plasma corticosterone levels increases the prevalence of serotonergic dorsal raphe neurons inhibitory responses to nicotine in adrenalectomised rats.
Topics: Aconitine; Action Potentials; Adrenalectomy; Animals; Corticosterone; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Male; Neural Inhibition; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Wistar; Serotonergic Neurons; Serotonin; Serotonin Antagonists | 2013 |
Effects of blockade of α4β2 and α7 nicotinic acetylcholine receptors on cue-induced reinstatement of nicotine-seeking behaviour in rats.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Conditioning, Operant; Cues; Dihydro-beta-Erythroidine; Drug-Seeking Behavior; Extinction, Psychological; Food; Male; Nicotine; Nicotinic Antagonists; Rats; Receptors, Nicotinic; Reinforcement Schedule; Self Administration | 2014 |
The effects of nicotine and tobacco particulate matter on dopamine uptake in the rat brain.
Topics: Aconitine; Animals; Brain; Dihydro-beta-Erythroidine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Mecamylamine; Nicotiana; Nicotine; Nicotinic Antagonists; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Plant Extracts; Rats; Rats, Sprague-Dawley; RNA, Messenger; Smoking; Tobacco Smoke Pollution | 2014 |
Nicotinic acetylcholine receptor antagonists alter the function and expression of serine racemase in PC-12 and 1321N1 cells.
Topics: Aconitine; Animals; Cell Line; Cell Line, Tumor; Gene Expression Regulation; Humans; Mecamylamine; Nicotine; Nicotinic Antagonists; PC12 Cells; Racemases and Epimerases; Rats; Receptors, Nicotinic; Signal Transduction; TOR Serine-Threonine Kinases | 2013 |
Genetic variation within the Chrna7 gene modulates nicotine reward-like phenotypes in mice.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bridged Bicyclo Compounds, Heterocyclic; Conditioning, Classical; Gene Regulatory Networks; Genetic Variation; Mice; Mice, Inbred C57BL; Nicotine; Nucleus Accumbens; Phenotype; Quantitative Trait Loci; Quinuclidines; Reward; RNA, Messenger | 2014 |
Role of neuronal nicotinic acetylcholine receptors (nAChRs) on learning and memory in zebrafish.
Topics: Aconitine; Alkaloids; Animals; Azocines; Cholinergic Agents; Conotoxins; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Maze Learning; Mecamylamine; Memory; Muscarinic Antagonists; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Quinolizines; Receptors, Nicotinic; Scopolamine; Swimming; Zebrafish; Zebrafish Proteins | 2014 |
Possible involvement of endogenous opioid system located downstream of α7 nicotinic acetylcholine receptor in mice with physical dependence on nicotine.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Biomarkers; Corticosterone; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Naloxone; Narcotic Antagonists; Nicotine; Opioid Peptides; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2014 |
A potentially novel nicotinic receptor in Aplysia neuroendocrine cells.
Topics: Acetylcholine; Aconitine; Action Potentials; Animals; Aplysia; Conotoxins; Dihydro-beta-Erythroidine; Hexamethonium; Mecamylamine; Neuroendocrine Cells; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Strychnine; Transcriptome | 2014 |
Corticosterone affects the differentiation of a neuronal cerebral cortex-derived cell line through modulation of the nicotinic acetylcholine receptor.
Topics: Aconitine; Animals; Cell Cycle; Cell Line; Cell Membrane; Cell Proliferation; Cerebral Cortex; Corticosterone; Mice; Neurogenesis; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Receptors, Nicotinic | 2014 |
(R,S)-Ketamine metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine increase the mammalian target of rapamycin function.
Topics: Aconitine; Animals; Blotting, Western; Brain; Excitatory Amino Acid Antagonists; Ketamine; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; PC12 Cells; Phosphorylation; Prefrontal Cortex; Rats; Rats, Wistar; Signal Transduction; TOR Serine-Threonine Kinases | 2014 |
Crystal structures of free and antagonist-bound states of human α9 nicotinic receptor extracellular domain.
Topics: Acetylcholine; Aconitine; Action Potentials; Animals; Bungarotoxins; Crystallography, X-Ray; Gene Expression; Humans; Models, Molecular; Mutation; Nicotine; Oocytes; Patch-Clamp Techniques; Pichia; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Receptors, Nicotinic; Recombinant Proteins; RNA, Complementary; Xenopus laevis | 2014 |
Protective role of the cholinergic anti-inflammatory pathway in a mouse model of viral myocarditis.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Cytokines; Enterovirus B, Human; Gene Expression Regulation; Interleukin-6; Mice; Mice, Inbred BALB C; Myocarditis; Nicotine; Signal Transduction; STAT3 Transcription Factor; Survival Analysis; Tumor Necrosis Factor-alpha | 2014 |
Modulation of aggressive behavior in mice by nicotinic receptor subtypes.
Topics: Aconitine; Aggression; Animals; Behavior, Animal; Dihydro-beta-Erythroidine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic | 2015 |
r-bPiDI, an α6β2* Nicotinic Receptor Antagonist, Decreases Nicotine-Evoked Dopamine Release and Nicotine Reinforcement.
Topics: Aconitine; Animals; Behavior, Animal; Conotoxins; Corpus Striatum; Dopamine; Male; Nicotine; Nicotinic Antagonists; Picolines; Pyridinium Compounds; Rats, Sprague-Dawley; Receptors, Nicotinic | 2015 |
Differential discriminative-stimulus effects of cigarette smoke condensate and nicotine in nicotine-discriminating rats.
Topics: Aconitine; Animals; Dihydro-beta-Erythroidine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Smoking; Time Factors | 2016 |
Alpha-7 nicotinic acetylcholine receptor (nAChR) agonist inhibits the development of endometriosis by regulating inflammation.
Topics: Aconitine; Adult; alpha7 Nicotinic Acetylcholine Receptor; Animals; Ascitic Fluid; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Endometriosis; Endometrium; Female; Gene Expression Regulation; Humans; Interleukin-1beta; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mice; Nicotine; Primary Cell Culture; Quinuclidines; RNA, Messenger; Severity of Illness Index; Signal Transduction | 2016 |
Chronic nicotine treatment decreases LPS signaling through NF-κB and TLR-4 modulation in the hippocampus.
Topics: Aconitine; Animals; Hippocampus; Inflammation; Lipopolysaccharides; Male; Mecamylamine; NF-kappa B; Nicotine; Nicotinic Agonists; Rats, Wistar; Receptors, Nicotinic; Signal Transduction; Toll-Like Receptor 4 | 2017 |
The contribution of α4β2 and non-α4β2 nicotinic acetylcholine receptors to the discriminative stimulus effects of nicotine and varenicline in mice.
Topics: Aconitine; Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Animals; Azocines; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Dihydro-beta-Erythroidine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Hypnotics and Sedatives; Ibogaine; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Midazolam; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Quinolizines; Receptors, Nicotinic; Varenicline | 2017 |
Alpha7 nicotinic acetylcholine receptor is required for amyloid pathology in brain endothelial cells induced by Glycoprotein 120, methamphetamine and nicotine.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Biomarkers; Blood-Brain Barrier; Brain; Cell Movement; Cellular Senescence; Endothelial Cells; HIV Envelope Protein gp120; HL-60 Cells; Humans; Methamphetamine; Mice, Inbred C57BL; Monocytes; Nicotine; Protein Transport; Receptor for Advanced Glycation End Products; S100 Proteins; Time Factors | 2017 |
The expression, localization and function of α7 nicotinic acetylcholine receptor in rat corpus cavernosum.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Guanethidine; Male; NG-Nitroarginine Methyl Ester; Nicotine; Penis; Phenylephrine; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction | 2017 |
The cholinergic anti-inflammatory pathway ameliorates acute viral myocarditis in mice by regulating CD4
Topics: Aconitine; Acute Disease; Animals; CD4-Positive T-Lymphocytes; Cell Differentiation; Cholinergic Agents; Coxsackievirus Infections; Flow Cytometry; Inflammation; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Myocarditis; Myocardium; Nicotine; Nicotinic Antagonists; Spleen; Th1 Cells; Th17 Cells | 2018 |
Nicotine improves probabilistic reward learning in wildtype but not alpha7 nAChR null mutants, yet alpha7 nAChR agonists do not improve probabilistic learning.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Mice; Mice, Knockout; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Punishment | 2018 |
Acute Activation of α7-Nicotinic Receptors by Nicotine Improves Rodent Skin Flap Survival Through Nitrergic System.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Arginine; Graft Survival; Guanidines; NG-Nitroarginine Methyl Ester; Nicotine; Nitric Oxide; Rats; Rats, Sprague-Dawley; Skin Transplantation; Surgical Flaps | 2019 |
Brainstem cholinergic pathways diminish cardiovascular and neuroinflammatory actions of endotoxemia in rats: Role of NFκB/α7/α4β2AChRs signaling.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Azetidines; Bradycardia; Bridged Bicyclo Compounds, Heterocyclic; Cholinergic Fibers; Dihydro-beta-Erythroidine; Endotoxemia; Hypotension; Infusions, Intraventricular; Lipopolysaccharides; Male; Medulla Oblongata; Neural Pathways; Neurogenic Inflammation; NF-kappa B; Nicotine; Pyridines; Quinuclidines; Rats; Receptors, Nicotinic; Signal Transduction; Solitary Nucleus; Tachycardia | 2019 |
Nicotine attenuates concanavalin A-induced liver injury in mice by regulating the α7-nicotinic acetylcholine receptor in Kupffer cells.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Cells, Cultured; Concanavalin A; Disease Models, Animal; Hepatitis, Autoimmune; Humans; Kupffer Cells; Liver; Male; Mice; NF-kappa B; Nicotine; Primary Cell Culture; Protective Agents; Signal Transduction | 2020 |
Kynurenine 3-monooxygenase deficiency induces depression-like behavior via enhanced antagonism of α7 nicotinic acetylcholine receptors by kynurenic acid.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Depression; Disease Models, Animal; Kynurenic Acid; Kynurenine 3-Monooxygenase; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex | 2021 |
Nicotine Enhances Object Recognition Memory via Stimulating α4β2 and α7 Nicotinic Acetylcholine Receptors in the Medial Prefrontal Cortex of Mice.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Dihydro-beta-Erythroidine; Male; Mecamylamine; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex; Receptors, Nicotinic; Recognition, Psychology | 2021 |
Cholinergic anti-inflammatory pathway ameliorates murine experimental Th2-type colitis by suppressing the migration of plasmacytoid dendritic cells.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Caspase 3; Caspase Inhibitors; Central Nervous System Stimulants; Cholinergic Neurons; Colitis, Ulcerative; Colon; Dendritic Cells; Deoxyglucose; Disease Models, Animal; Enzyme Inhibitors; Janus Kinase 2; Mice, Inbred BALB C; Neuroimmunomodulation; Neuropeptides; Nicotine; Oxazolone; rac1 GTP-Binding Protein; STAT3 Transcription Factor; Th2 Cells; Tyrphostins; Vagus Nerve | 2022 |