nicotine has been researched along with metformin in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 13 (65.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Babu, E; Ganapathy, V; Ho, HT; Itagaki, S; Wang, J; Zhou, M | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Aicher, A; Barbacid, M; Cañamero, M; de Pascual, R; Gandia, L; Gress, T; Guerra, C; Heeschen, C; Hermann, PC; Madriles, F; Martinelli, P; Michl, P; Real, FX; Sainz, B; Sancho, P; Vieira, CR; Wagner, M | 1 |
| Guo, M; Ji, X; Li, R; Liang, W; Mao, Y; Qin, X; Sheng, X; Song, Y; Wang, F; Xiao, J; Zhang, X | 1 |
| Jakova, E; Lee, JS | 1 |
| Blendy, JA; Brynildsen, JK; Jin, S; Kim, SF; Lee, BG; Perron, IJ | 1 |
| López, M | 1 |
| Finley, J | 1 |
| Liu, SY; Shao, XT; Song, XB; Tan, DQ; Wang, DG; Wang, Z | 1 |
| Cong, ZX; Liu, SY; Shao, XT; Wang, DG; Wang, Z; Zheng, XY | 1 |
| Chen, Y; Du, L; Gao, S; Geary, K; Guo, Y; Lin, Y; Pan, Y; Wang, L; Wang, S; Xiong, X; Yao, Z; Yeung, SJ; Zhang, D; Zhang, H; Zhou, F; Zhu, J | 1 |
1 review(s) available for nicotine and metformin
| Article | Year |
|---|---|
Hypothalamic AMPK and energy balance.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; AMP-Activated Protein Kinases; Animals; Anti-Obesity Agents; Antipsychotic Agents; Energy Metabolism; Feeding Behavior; Glucose; Homeostasis; Humans; Hypoglycemic Agents; Hypothalamus; Liraglutide; Liver; Metformin; Muscles; Nicotine; Nicotinic Agonists; Signal Transduction; Thermogenesis; Weight Gain | 2018 |
19 other study(ies) available for nicotine and metformin
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Electrophysiological characterization of the polyspecific organic cation transporter plasma membrane monoamine transporter.
Topics: Animals; Cell Membrane; Electrophysiological Phenomena; Equilibrative Nucleoside Transport Proteins; Female; Humans; Membrane Potentials; Organic Cation Transport Proteins; Xenopus laevis; Xenopus Proteins | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
Topics: Acinar Cells; alpha7 Nicotinic Acetylcholine Receptor; Animals; Carcinoma, Pancreatic Ductal; Cell Dedifferentiation; Cell Line, Tumor; Cell Transformation, Neoplastic; Epithelial-Mesenchymal Transition; Extracellular Signal-Regulated MAP Kinases; GATA6 Transcription Factor; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Metformin; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Mutation; Neoplastic Cells, Circulating; Neoplastic Stem Cells; Nicotine; Nicotinic Agonists; Pancreas; Pancreatic Neoplasms; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins p21(ras); Signal Transduction; Time Factors; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2014 |
Metformin alleviates vascular calcification induced by vitamin D3 plus nicotine in rats via the AMPK pathway.
Topics: AMP-Activated Protein Kinases; Animals; Cholecalciferol; Male; Metformin; Nicotine; Rats; Rats, Wistar; Signal Transduction; Vascular Calcification | 2016 |
Behavior of α-synuclein-drug complexes during nanopore analysis with a superimposed AC field.
Topics: alpha-Synuclein; Caffeine; Electricity; Electrophoresis; Humans; Metformin; Models, Chemical; Nanopores; Nicotine; Parkinson Disease; Pharmaceutical Preparations | 2017 |
Activation of AMPK by metformin improves withdrawal signs precipitated by nicotine withdrawal.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Anxiety Disorders; Drug Evaluation, Preclinical; Enzyme Activation; Feeding Behavior; Gene Knockdown Techniques; Hippocampus; Male; Metformin; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Nerve Tissue Proteins; Nicotine; Ribonucleotides; Signal Transduction; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2018 |
Cellular stress and AMPK links metformin and diverse compounds with accelerated emergence from anesthesia and potential recovery from disorders of consciousness.
Topics: AMP-Activated Protein Kinases; Anesthesia; Anesthesia Recovery Period; Anesthetics; Animals; Brain Mapping; Calcium; Cell Lineage; Cell Proliferation; Consciousness; Consciousness Disorders; Dexmedetomidine; Humans; Isoflurane; Ketamine; Learning; Long-Term Potentiation; Memory; Metformin; Midazolam; Models, Neurological; Nicotine; Propofol; Reactive Oxygen Species; Sevoflurane; Unconsciousness | 2019 |
Assessment of metformin, nicotine, caffeine, and methamphetamine use during Chinese public holidays.
Topics: Caffeine; China; Cities; Holidays; Humans; Metformin; Methamphetamine; Nicotine; Substance-Related Disorders; Wastewater; Water Pollutants, Chemical | 2020 |
Spatial analysis of metformin use compared with nicotine and caffeine consumption through wastewater-based epidemiology in China.
Topics: Caffeine; China; Cities; Diabetes Mellitus, Type 2; Humans; Metformin; Nicotiana; Nicotine; Spatial Analysis; Tobacco Use; Wastewater; Wastewater-Based Epidemiological Monitoring | 2021 |
Repurposing dextromethorphan and metformin for treating nicotine-induced cancer by directly targeting CHRNA7 to inhibit JAK2/STAT3/SOX2 signaling.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Carcinogenesis; Cell Line, Tumor; Dextromethorphan; DNA Methylation; Drug Repositioning; Electronic Nicotine Delivery Systems; Esophageal Squamous Cell Carcinoma; Female; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Janus Kinase 2; Male; Metformin; Mice; Nicotine; SOXB1 Transcription Factors; STAT3 Transcription Factor | 2021 |