nicotine has been researched along with lidocaine in 75 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (48.00) | 18.7374 |
| 1990's | 4 (5.33) | 18.2507 |
| 2000's | 24 (32.00) | 29.6817 |
| 2010's | 10 (13.33) | 24.3611 |
| 2020's | 1 (1.33) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Caron, G; Ermondi, G | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Carrupt, PA; Martel, S; Ottaviani, G | 2 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Bianucci, AM; Calderone, V; Coi, A; Massarelli, I; Testai, L | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Bard, B; Carrupt, PA; Martel, S | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Yaffe, SJ | 1 |
| Izumi, H; Karita, K | 1 |
| Gomi, Y; Suzuki, N | 1 |
| Cherniack, NS; Haxhiu, MA; Van Lunteren, E | 1 |
| Chen, Z; Engberg, G | 1 |
| Cherniack, NS; Deal, EC; Haxhiu, MA; Mitra, J; Norcia, MP; Van Lunteren, E | 1 |
| DeNoble, VJ; Mele, PC | 1 |
| Deal, EC; Haxhiu, MA; Norcia, MP; Strohl, KP; van Lunteren, E; Wolin, AD | 1 |
| Alaranta, S; Klinge, E; Sjöstrand, NO | 1 |
| de la Garza, R; Johanson, CE | 1 |
| Kitagawa, H; Kohei, H; Takeda, F | 1 |
| Westfall, TC | 1 |
| Aihara, H; Otsuki, K; Ozawa, M | 1 |
| Domino, EF | 1 |
| Bennett, A; Whitney, B | 1 |
| Feng, PC; Gaskin, RS | 1 |
| Beckett, AH; Triggs, EJ | 1 |
| Wood, JD | 1 |
| Alps, BJ; Fidler, K; Hill, M; Johnson, ES; Wilson, AB | 1 |
| Okawa, H | 1 |
| Brasted, M; Westfall, TC | 1 |
| Abrahamsson, H; Thorén, P | 1 |
| Ohkawa, H; Prosser, CL | 1 |
| Staszewska-Barczak, J | 1 |
| Frink, RJ; James, TN | 1 |
| Ogawa, T | 1 |
| Priest, WC; Sabelli, HC | 1 |
| Bass, P; Hug, CC; Weisbrodt, NW; Weisenthal, LM | 1 |
| Watson, PJ | 1 |
| Bennett, A; Fleshler, B | 1 |
| Aviado, DM; Peskin, GW; Samanek, M | 1 |
| Aviado, DM; Samanék, M | 1 |
| Andersson, A; Olsson, S; Tjälve, H | 1 |
| Fielden, R | 1 |
| Jones, DR; Milsom, WK; West, NH | 1 |
| Diana, JN; Dowell, RT; Houdi, AA | 1 |
| Pragst, F; Sporkert, F | 1 |
| Higo, A; Katsura, M; Mohri, Y; Ohkuma, S; Shuto, K; Takesue, M; Tarumi, C; Tsujimura, A | 1 |
| Acosta, S; Miles, R; Strahlendorf, HK; Strahlendorf, JC | 1 |
| Ha, H; Kim, KT; Lee, TG; Park, TJ; Park, YS | 1 |
| BIRMINGHAM, AT; WILSON, AB | 1 |
| KOELLA, WP; SCHAEPPI, U | 1 |
| ADRIANI, J; MULLEN, J | 1 |
| DAS, PK; SANYAL, AK; SINHA, PS | 1 |
| Anggadiredja, K; Hiranita, T; Nawata, Y; Sakimura, K; Yamamoto, T | 1 |
| Beaugerie, L; Cosnes, J; Daniel, F; Marteau, P; Seksik, P | 1 |
| Bhatti, AS; Hall, P; Isgor, C; Ma, Z; Tao, R | 1 |
| Damaj, BB; Hu, L; Martin, R; Michniak-Kohn, BB; Silva, SM | 1 |
| Hu, L; Michniak-Kohn, B; Simon, L; Wei, R | 1 |
| Ali Beig, H; Bourbour, Z; Chalabi-Yani, D; Hosseini, SB; Meftahi, GH; Ranjabaran, M; Sadeghi-Gharajehdaghi, S; Sahraei, H | 1 |
| Bischoff, R; Fraaije, MW; Gul, T; Krzek, M; Permentier, HP | 1 |
| Bevins, RA; Charntikov, S; Li, M; Pittenger, ST; Swalve, N | 1 |
| Bunge, AL; Delgado-Charro, MB; Guy, RH; Hoppel, M; Tabosa, MAM | 1 |
1 review(s) available for nicotine and lidocaine
| Article | Year |
|---|---|
[Refractory proctitis].
Topics: Administration, Oral; Adrenal Cortex Hormones; Algorithms; Anesthetics, Local; Antibodies, Monoclonal; Aspirin; Azathioprine; Biopsy; Cyclosporine; Drug Therapy, Combination; Escherichia coli; Forecasting; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Infliximab; Lidocaine; Methotrexate; Nicotine; Patient Compliance; Probiotics; Proctitis; Randomized Controlled Trials as Topic; Rectum; Suppositories; Time Factors | 2007 |
1 trial(s) available for nicotine and lidocaine
| Article | Year |
|---|---|
Assessment of Drug Delivery Kinetics to Epidermal Targets In Vivo.
Topics: Administration, Cutaneous; Adult; Animals; Drug Evaluation, Preclinical; Epidermis; Female; Healthy Volunteers; Humans; Lidocaine; Male; Nicotine; Skin Absorption; Skin Cream; Swine; Transdermal Patch | 2021 |
73 other study(ies) available for nicotine and lidocaine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability.
Topics: 1-Octanol; Diffusion; Dimethylpolysiloxanes; Humans; In Vitro Techniques; Membranes, Artificial; Myristates; Permeability; Skin; Skin Absorption; Water | 2006 |
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water | 2007 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation.
Topics: Amino Acid Sequence; Heart; Humans; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Subunits; Sequence Alignment; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
A clinical look at the problem of drugs in pregnancy and their effect on the fetus.
Topics: Abnormalities, Drug-Induced; Anesthesia, Obstetrical; Aspirin; Drug-Related Side Effects and Adverse Reactions; Female; Fetus; Folic Acid Antagonists; Humans; Infant, Newborn; Infant, Newborn, Diseases; Lidocaine; Maternal-Fetal Exchange; Meperidine; Mepivacaine; Nicotine; Physician-Patient Relations; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Scotland; Smoking; Thalidomide; United States | 1975 |
Axon reflex flare evoked by nicotine in human skin.
Topics: Adult; Axons; Capsaicin; Diphenhydramine; Female; Humans; Injections, Intradermal; Lidocaine; Male; Middle Aged; Nerve Fibers; Nicotine; Receptors, Histamine; Reflex; Regional Blood Flow; Skin; Vasodilation | 1992 |
Evidence that stretch receptors for peristalsis are located in the mucosal layer of the guinea pig ileum.
Topics: Animals; Guinea Pigs; Ileum; In Vitro Techniques; Intestinal Mucosa; Lidocaine; Male; Mechanoreceptors; Morphine; Muscle Contraction; Muscle, Smooth; Nicotine; Peristalsis; Tetrodotoxin | 1992 |
Influence of ventrolateral surface of medulla on tracheal gland secretion.
Topics: Animals; Atropine; Dogs; Exocrine Glands; Female; Lidocaine; Male; Medulla Oblongata; Mucous Membrane; Nicotine; Reflex; Trachea | 1991 |
The rat nucleus paragigantocellularis as a relay station to mediate peripherally induced central effects of nicotine.
Topics: Animals; Injections, Intravenous; Injections, Intraventricular; Lidocaine; Locus Coeruleus; Male; Medulla Oblongata; Neurons; Nicotine; Rats | 1989 |
Medullary effects of nicotine and GABA on tracheal smooth muscle tone.
Topics: Administration, Topical; Airway Resistance; Animals; Bicuculline; Carbon Dioxide; Cats; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hexamethonium; Hexamethonium Compounds; Lidocaine; Male; Medulla Oblongata; Nicotine; Phrenic Nerve; Trachea | 1986 |
Brain sites involved in the mediation of the behavioral effects of intraventricularly administered (-)-nicotine.
Topics: Animals; Behavior, Animal; Brain; Injections, Intraventricular; Lidocaine; Male; Nicotine; Rats | 1986 |
Nasal and tracheal responses to chemical and somatic afferent stimulation in anesthetized cats.
Topics: Airway Resistance; Animals; Carbon Dioxide; Cats; Female; Lidocaine; Male; Medulla Oblongata; Nicotine; Nose; Respiration; Sciatic Nerve; Trachea | 1988 |
Pharmacological analysis of nicotinic relaxation of bovine retractor penis muscle.
Topics: Acetylcholine; Animals; Carbachol; Cattle; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Hexamethonium Compounds; Lidocaine; Male; Mecamylamine; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nicotine; Oxygen; Penis; Scopolamine; Tetrodotoxin | 1988 |
Discriminative stimulus properties of cocaine in pigeons.
Topics: Alkaloids; Animals; Apomorphine; Cocaine; Columbidae; Dextroamphetamine; Discrimination, Psychological; Dopamine; Lidocaine; Nicotine; Oxazepam; Pentobarbital; Procaine; Psychotropic Drugs; Reinforcement Schedule | 1985 |
Inhibition of sympathetic nervous system by mexiletine, an antiarrhythmic agent, and its antagonism against ouabain.
Topics: Animals; Aorta, Thoracic; Arrhythmias, Cardiac; Electric Stimulation; Epinephrine; Guinea Pigs; In Vitro Techniques; Lidocaine; Male; Mexiletine; Muscle Contraction; Muscle, Smooth, Vascular; Nicotine; Norepinephrine; Ouabain; Portal Vein; Potassium Chloride; Propylamines; Pulmonary Artery; Rabbits; Rats; Rats, Inbred Strains; Sympatholytics; Tyramine | 1985 |
Effect of nicotine and other drugs on the release of 3H-norepinephrine and 3H-dopamine from rat brain slices.
Topics: Acetylcholine; Animals; Brain; Carbachol; Cerebellum; Cerebral Cortex; Cocaine; Corpus Striatum; Culture Media; Deamination; Dopamine; Edetic Acid; Hexamethonium Compounds; Hypothalamus; In Vitro Techniques; Lidocaine; Methacholine Compounds; Methylation; Morphine; Nicotine; Norepinephrine; Peripheral Nerves; Phenoxybenzamine; Rats; Tritium | 1974 |
[Effect of lidocaine on ganglionic transmission].
Topics: Acetylcholine; Animals; Blood Pressure; Cats; Electric Stimulation; Epinephrine; Female; Ganglia, Autonomic; Humans; Injections, Intra-Articular; Injections, Intravenous; Lidocaine; Male; Nicotine; Norepinephrine; Potassium Chloride; Procainamide; Procaine; Scopolamine; Synaptic Transmission; Tetraethylammonium Compounds | 1967 |
A role of the central nervous system in the cardiovascular actions of nicotine.
Topics: Anesthesia, Spinal; Anesthetics; Animals; Blood Pressure; Cardiovascular System; Central Nervous System; Chemoreceptor Cells; Decamethonium Compounds; Decerebrate State; Dogs; Drug Antagonism; Epinephrine; Female; Ganglia; Lidocaine; Male; Nicotine; Norepinephrine; Pentobarbital; Piperazines; Reticular Formation; Spinal Cord; Synaptic Transmission | 1969 |
A pharmacological investigation of human isolated stomach.
Topics: Acetylcholine; Cocaine; Epinephrine; Ergoloid Mesylates; Ethanolamines; Guanethidine; Hexamethonium Compounds; Histamine; Histamine H1 Antagonists; Humans; In Vitro Techniques; Isoproterenol; Lidocaine; Methysergide; Neostigmine; Nicotine; Norepinephrine; Pentolinium Tartrate; Physostigmine; Piperazines; Potassium Chloride; Scopolamine; Serotonin; Stomach; Sympathomimetics | 1966 |
Some pharmacological activities of crotonosine and pronuciferine.
Topics: Acetylcholine; Anesthetics; Animals; Anura; Diaphragm; Drug Antagonism; Drug Synergism; Electric Stimulation; Electrophysiology; Guinea Pigs; Ileum; In Vitro Techniques; Lidocaine; Muscle Contraction; Muscles; Neostigmine; Nicotine; Plant Extracts; Plants, Medicinal; Poultry; Procaine; Rats; Tubocurarine | 1967 |
Buccal absorption of basic drugs and its application as an in vivo model of passive drug transfer through lipid membranes.
Topics: Adult; Amines; Amphetamine; Appetite Depressants; Benzphetamine; Biological Transport; Chlorpheniramine; Chlorphentermine; Ephedrine; Fenfluramine; Furans; Humans; Hydrogen-Ion Concentration; Lidocaine; Male; Membranes; Meperidine; Mephentermine; Methadone; Models, Biological; Morpholines; Mouth; Nicotine; Phenethylamines; Phenmetrazine; Phenylpropanolamine | 1967 |
Electrophysiological and pharmacological properties of the stomach of the squid Loligo pealii (Lesueur).
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Depression, Chemical; Electrophysiology; Epinephrine; Ethanolamines; Gastrointestinal Motility; Lidocaine; Mollusca; Muscle, Smooth; Nicotine; Phenoxybenzamine; Procaine; Quinones; Scopolamine; Serotonin; Stomach; Tetrodotoxin; Tubocurarine | 1969 |
The reversal of experimental cardiac arrhythmias by indoramin (Wy 21901).
Topics: Amides; Anesthetics, Local; Animals; Arrhythmia, Sinus; Arrhythmias, Cardiac; Blood Pressure; Cats; Epinephrine; Female; Guinea Pigs; Halothane; Ileum; In Vitro Techniques; Indoles; Lidocaine; Male; Muscle Contraction; Nicotine; Ouabain; Piperidines; Procaine; Propranolol; Quinidine; Tachycardia; Ventricular Fibrillation | 1971 |
[Adrenergic and cholinergic mechanisms in the hypogastric nerve-seminal vesicle preparation of the guinea-pig (author's transl)].
Topics: Acetylcholine; Animals; Atropine; Carbachol; Epinephrine; Guanethidine; Guinea Pigs; Hexamethonium Compounds; Hypogastric Plexus; In Vitro Techniques; Lidocaine; Male; Methacholine Compounds; Neostigmine; Nialamide; Nicotine; Norepinephrine; Phenoxybenzamine; Phenylephrine; Physostigmine; Seminal Vesicles; Sympathetic Nervous System; Tetrodotoxin | 1973 |
Specificity of blockade of the nicotine-induced release of 3H-norepinephrine from adrenergic neurons of the guinea-pig heart by various pharmacological agents.
Topics: Aminophylline; Animals; Bretylium Compounds; Cocaine; Colchicine; Guinea Pigs; Heart; Hexamethonium Compounds; In Vitro Techniques; Lidocaine; Morphine; Myocardium; Neurons; Nicotine; Norepinephrine; Perfusion; Potassium Chloride; Prostaglandins; Stimulation, Chemical; Tritium; Tyramine | 1974 |
Reflex relaxation of the stomach elicited from receptors located in the heart. An analysis of the receptors and afferents involved.
Topics: Animals; Aorta; Blood Pressure; Cats; Electric Stimulation; Evoked Potentials; Heart Conduction System; Heart Rate; Heart Ventricles; Lidocaine; Neural Conduction; Nicotine; Plants, Medicinal; Plants, Toxic; Pulmonary Artery; Reflex; Sensory Receptor Cells; Stomach; Time Factors; Vagus Nerve; Veratrum; Vomiting | 1972 |
Functions of neurons in enteric plexuses of cat intestine.
Topics: Acetylcholine; Animals; Atropine; Cats; Electrophysiology; Epinephrine; Hexamethonium Compounds; In Vitro Techniques; Intestine, Small; Lidocaine; Muscle, Smooth; Myenteric Plexus; Neural Inhibition; Nicotine; Norepinephrine; Phenoxybenzamine; Serotonin; Sotalol; Submucous Plexus; Tetrodotoxin; Tubocurarine | 1972 |
The reflex stimulation of catecholamine secretion during the acute stage of myocardial infarction in the dog.
Topics: Acetylcholine; Adrenal Medulla; Animals; Bradykinin; Bretylium Compounds; Chlorisondamine; Dogs; Epinephrine; Female; Guanethidine; Heart; Lidocaine; Ligation; Male; Myocardial Infarction; Nerve Endings; Nicotine; Norepinephrine; Pentolinium Tartrate; Reflex; Reserpine; Secretory Rate; Spinal Nerves; Splanchnic Nerves; Sympathetic Nervous System; Time Factors; Vagotomy; Vagus Nerve | 1971 |
Intracardiac route of the Bezold-Jarisch reflex.
Topics: Animals; Bradycardia; Coronary Vessels; Dogs; Electrocardiography; Heart; Heart Block; Heart Conduction System; Heart Rate; Heart Ventricles; Hypotension; Lidocaine; Neurons, Afferent; Nicotine; Reflex; Vagus Nerve | 1971 |
Local effect of skin temperature on threshold concentration of sudorific agents.
Topics: Acetylcholine; Axons; Epinephrine; Hot Temperature; Humans; Injections, Intradermal; Lidocaine; Male; Methods; Nicotine; Pilocarpine; Procaine; Reflex; Skin Temperature; Sweat Glands; Sweating | 1970 |
Water structure in anesthetic action: time-dependence D2O effects on nerve.
Topics: Action Potentials; Anesthesia; Anesthetics; Anesthetics, Local; Animals; Anura; Calcium; Cocaine; Depression, Chemical; Deuterium; Ethanol; Ethyl Ethers; Glucose; In Vitro Techniques; Lidocaine; Models, Biological; Neural Conduction; Nicotine; Ouabain; Oxides; Phosphates; Procaine; Sciatic Nerve; Stimulation, Chemical; Temperature; Time Factors; Water | 1970 |
Adrenergic mechanisms in the relaxation of guinea-pig taenia coli in vitro.
Topics: Animals; Catecholamines; Colon; Electric Stimulation; Female; Guanethidine; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Lidocaine; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Nicotine; Phentolamine; Potassium; Propranolol; Sympathetic Nervous System; Tetrodotoxin; Tolazoline | 1971 |
Interaction between acetylcholine and guanethidine on sensory C fibres.
Topics: Acetylcholine; Action Potentials; Animals; Axons; Blood Pressure; Carbachol; Dextroamphetamine; Electric Stimulation; Guanethidine; Hexamethonium Compounds; Isoproterenol; Lidocaine; Nicotine; Oscillometry; Peripheral Nerves; Piperazines; Potassium Chloride; Rabbits; Sympathetic Nervous System; Thigh | 1967 |
Action of prostaglandin E 1 on the longitudinal muscle of the guinea-pig isolated colon.
Topics: Acetylcholine; Animals; Cocaine; Colon; Guinea Pigs; In Vitro Techniques; Lidocaine; Muscle, Smooth; Nicotine; Prostaglandins; Scopolamine; Tetrodotoxin | 1969 |
Bronchopulmonary effects of tobacco and related substances. 3. Axon reflexes elicited from the visceral pleura.
Topics: Animals; Bronchi; Denervation; Dogs; Histamine; Lidocaine; Nicotine; Pleura; Reflex; Vagotomy | 1965 |
Cardiopulmonary effects of tobacco and related substances. 3. Pulmonary vascular effects of cigarette smoke and nicotine.
Topics: Animals; Blood Pressure; Bronchospirometry; Dogs; Hypertension, Pulmonary; Lidocaine; Lung; Nicotine; Perfusion; Pulmonary Artery; Pulmonary Circulation; Respiratory Function Tests; Smoking; Sympathectomy | 1966 |
The uptake of 14C-chloroquine by mouse pancreatic islets in vitro.
Topics: Absorption; Animals; Chloroquine; Chlorpromazine; Desipramine; Glucose; Hydrogen-Ion Concentration; Imipramine; Islets of Langerhans; Lidocaine; Mice; Nicotine; Nitrogen; Ouabain; Quinacrine; Temperature | 1980 |
The discovery of the noradrenergic neurone blocking action of TM10 (xylocholine).
Topics: Choline; England; History, 20th Century; Humans; Lidocaine; Nicotine; Norepinephrine; Pharmacology; Sympatholytics | 1981 |
Cardiac receptors in ducks: the effect of their stimulation and blockade on diving bradycardia.
Topics: Animals; Blood Pressure; Diving; Ducks; Heart; Heart Rate; Lidocaine; Nicotine; Pressoreceptors; Vagus Nerve; Ventricular Function | 1980 |
Cardiovascular responses to cigarette smoke exposure in restrained conscious rats.
Topics: Animals; Arginine Vasopressin; Atropine; Blood Pressure; Heart Rate; Lidocaine; Male; Muscarinic Antagonists; Naloxone; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Opioid; Restraint, Physical; Smoking; Stress, Psychological | 1995 |
Use of headspace solid-phase microextraction (HS-SPME) in hair analysis for organic compounds.
Topics: Antidepressive Agents, Tricyclic; Cannabinoids; Chlormethiazole; Diphenhydramine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Lidocaine; Methadone; Nicotine; Poisoning; Sensitivity and Specificity; Solvents; Substance Abuse Detection; Tramadol | 2000 |
Mechanism for increase in expression of cerebral diazepam binding inhibitor mRNA by nicotine: involvement of L-type voltage-dependent calcium channels.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Anesthetics, Local; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Radioisotopes; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cells, Cultured; Cerebral Cortex; Diazepam Binding Inhibitor; Dibucaine; Enzyme Inhibitors; Gene Expression; Hexamethonium; Lidocaine; Membrane Potentials; Mice; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; omega-Agatoxin IVA; omega-Conotoxin GVIA; Platelet Aggregation Inhibitors; Procainamide; RNA, Messenger; Sulfonamides; Tetrodotoxin; Tritium | 2000 |
Choline blocks AMPA-induced dark cell degeneration of Purkinje neurons: potential role of the alpha7 nicotinic receptor.
Topics: Aconitine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; alpha7 Nicotinic Acetylcholine Receptor; Animals; Choline; Excitatory Amino Acid Agonists; Extracellular Space; Female; Gluconates; Insecticides; Lidocaine; Male; Meglumine; Nerve Degeneration; Neurotoxins; Nicotine; Nootropic Agents; Organ Culture Techniques; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Nicotinic; Sodium; Sodium Channels; Sodium Chloride; Tetrodotoxin | 2001 |
Inhibition of acetylcholine-mediated effects by borneol.
Topics: Acetylcholine; Anesthetics, Local; Animals; Calcium; Camphanes; Cattle; Chromaffin Cells; Drug Interactions; Exocytosis; Lidocaine; Nicotine; Receptors, Nicotinic; Signal Transduction; Sodium | 2003 |
PREGANGLIONIC AND POSTGANGLIONIC STIMULATION OF THE GUINEA-PIG ISOLATED VAS DEFERENS PREPARATION.
Topics: Acetylcholine; Animals; Atropine; Bretylium Compounds; Dextroamphetamine; Electric Stimulation; Electrophysiology; Ergotamine; Ganglia; Ganglia, Spinal; Ganglionic Blockers; Guanethidine; Guinea Pigs; Hexamethonium Compounds; Humans; Lidocaine; Male; Mecamylamine; Nicotine; Norepinephrine; Pentolinium Tartrate; Pharmacology; Phentolamine; Potassium; Procaine; Research; Scopolamine; Vas Deferens | 1963 |
REACTION OF ISOLATED PIG IRIS SPHINCTER TO ELECTRICAL STIMULATION AND ACETYLCHOLINE.
Topics: Acetylcholine; Animals; Atropine; Electric Stimulation; Electrophysiological Phenomena; Electrophysiology; Hexamethonium Compounds; Iodoacetates; Iris; Isoflurophate; Lidocaine; Neostigmine; Nicotine; Research; Swine | 1964 |
A CLINICAL APPRAISAL OF DRUGS USED FOR CARDIORESPIRATORY RESUSCITATION.
Topics: Amphetamine; Amphetamines; Barium; Bemegride; Bicarbonates; Calcium; Cyanides; Epinephrine; Humans; Isoproterenol; Lactates; Lidocaine; Lobeline; Methylphenidate; Nalorphine; Nicotine; Nikethamide; Norepinephrine; Pentylenetetrazole; Pharmacology; Picrotoxin; Potassium; Procaine; Resuscitation; Toxicology | 1964 |
STUDIES ON CILIARY MOVEMENTS: I. MECHANISM OF CILIARY MOVEMENT IN FROG'S OESOPHAGUS.
Topics: Acetylcholine; Animals; Anura; Atropine; Cilia; Epinephrine; Ergotamine; Esophagus; Histamine; Lidocaine; Movement; Nicotine; Pentolinium Tartrate; Pharmacology; Physostigmine; Procaine; Quinine; Research; Sympathetic Nervous System; Tolazoline | 1964 |
Suppression of methamphetamine-seeking behavior by nicotinic agonists.
Topics: Acetylcholinesterase; Animals; Behavior, Animal; Brain; Cholinesterase Inhibitors; Donepezil; Indans; Lidocaine; Male; Mecamylamine; Methamphetamine; Nicotine; Nicotinic Agonists; Piperidines; Rats; Rats, Wistar; Receptors, Nicotinic; Scopolamine | 2006 |
Hippocampus modulates the behaviorally-sensitizing effects of nicotine in a rat model of novelty-seeking: potential role for mossy fibers.
Topics: Age Factors; Anesthetics, Local; Animals; Animals, Newborn; Behavior, Animal; Exploratory Behavior; Hippocampus; Lidocaine; Male; Models, Animal; Mossy Fibers, Hippocampal; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Silver Staining | 2007 |
Transdermal and transbuccal drug delivery systems: enhancement using iontophoretic and chemical approaches.
Topics: Administration, Buccal; Administration, Cutaneous; Alanine; Animals; Azepines; Diltiazem; Drug Delivery Systems; In Vitro Techniques; Iontophoresis; Lidocaine; Mouth Mucosa; Nicotine; Skin; Skin Absorption; Sulfur Compounds; Swine | 2011 |
Effects of iontophoresis and chemical enhancers on the transport of lidocaine and nicotine across the oral mucosa.
Topics: Administration, Buccal; Animals; Biological Transport; Chemistry, Pharmaceutical; Diffusion; Drug Delivery Systems; Gels; Iontophoresis; Lidocaine; Mouth Mucosa; Nicotine; Swine | 2012 |
Effect of Transient Inactivation of Ventral Tegmental Area on the Expression and Acquisition of Nicotine-Induced Conditioned Place Preference in Rats.
Topics: Anesthetics, Local; Animals; Conditioning, Psychological; Diazepam; Dopaminergic Neurons; Ketamine; Lidocaine; Male; Nicotine; Rats; Rats, Wistar; Reward; Ventral Tegmental Area | 2015 |
Microbial Flavoprotein Monooxygenases as Mimics of Mammalian Flavin-Containing Monooxygenases for the Enantioselective Preparation of Drug Metabolites.
Topics: Albendazole; Aniline Compounds; Bacterial Proteins; Biotransformation; Chromatography, High Pressure Liquid; Fenbendazole; Lidocaine; Nicotine; Oxidation-Reduction; Oxygenases; Rhodococcus; Substrate Specificity; Sulfoxides; Tandem Mass Spectrometry; Xenobiotics | 2016 |
Double dissociation of the anterior and posterior dorsomedial caudate-putamen in the acquisition and expression of associative learning with the nicotine stimulus.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Association Learning; Caudate Nucleus; Conditioning, Psychological; Drug Administration Routes; Excitatory Amino Acid Agonists; Lidocaine; Male; N-Methylaspartate; Nicotine; Nicotinic Agonists; Putamen; Rats; Rats, Sprague-Dawley | 2017 |