Page last updated: 2024-08-26

nicotine and kynurenic acid

nicotine has been researched along with kynurenic acid in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's1 (6.25)18.2507
2000's7 (43.75)29.6817
2010's2 (12.50)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Beart, PM; Marley, PD; Mercer, LD; O'Shea, RD1
Engberg, G1
Engberg, G; Grenhoff, J; Svensson, TH; Tung, CS; Ugedo, L1
el-Mofty, MM1
Abdel-Tawab, GA; el-Shafei, AK; el-Zoghby, SM; Kelada, FS1
Engberg, G; Erhardt, S; Hajos, M; Lindberg, A1
Arun, P; Deepadevi, KV; Kurup, PA; Manojkumar, V; Ravikumar, A1
Engberg, G; Erhardt, S; Oberg, H1
Albuquerque, EX; Alkondon, M; Hilmas, C; Pereira, EF; Rassoulpour, A; Schwarcz, R1
Ceresoli-Borroni, G; Guidetti, P; Kiss, C; Schwarcz, R; Zielke, CL; Zielke, HR1
Albuquerque, EX; Rassoulpour, A; Schwarcz, R; Wu, HQ1
Dekundy, A; Kuc, D; Turski, WA; Zgrajka, W; Zielińska, E1
Gritton, H; Johnson, DE; Koshy Cherian, A; Kozak, R; Sarter, M; Young, D1
Auber, A; Goldberg, SR; Justinova, Z; Panlilio, LV; Redhi, GH; Schindler, CW; Schwarcz, R; Secci, ME; Thorndike, EB1
Arias, H; Bruno, JP; Phenis, D; Schwarcz, R; Valentini, V; Vunck, SA1
Fujigaki, H; Fujigaki, S; Hasegawa, M; Hirakawa, M; Hoshi, M; Kosuge, A; Kubota, H; Kunisawa, K; Kurahashi, H; Mori, Y; Mouri, A; Murakami, R; Nabeshima, T; Nakano, T; Niijima, M; Saito, K; Yamamoto, Y1

Other Studies

16 other study(ies) available for nicotine and kynurenic acid

ArticleYear
Biochemical, autoradiographic and functional studies on a unique glutamate binding site in adrenal gland.
    Journal of the autonomic nervous system, 1992, Volume: 40, Issue:1

    Topics: Adrenal Glands; Animals; Autoradiography; Binding Sites; Binding, Competitive; Catecholamines; Cattle; Dogs; Female; Glutamates; Glutamic Acid; Guinea Pigs; Kinetics; Kynurenic Acid; Male; Nicotine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Tissue Distribution

1992
Nicotine induced excitation of locus coeruleus neurons is mediated via release of excitatory amino acids.
    Life sciences, 1989, Volume: 44, Issue:21

    Topics: Action Potentials; Amino Acids; Animals; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Kynurenic Acid; Locus Coeruleus; Male; Neurons; Nicotine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter

1989
Peripheral induction of burst firing in locus coeruleus neurons by nicotine mediated via excitatory amino acids.
    Synapse (New York, N.Y.), 1989, Volume: 4, Issue:4

    Topics: Action Potentials; Amino Acids; Animals; Injections, Intravenous; Kynurenic Acid; Locus Coeruleus; Male; Nicotine; Peripheral Nerves; Rats; Rats, Inbred Strains

1989
A new biological assay, utilizing parasitic protozoa, for screening carcinogenic substances which induce bladder cancer in man and other mammals.
    International journal for parasitology, 1974, Volume: 4, Issue:1

    Topics: Acetamides; Amines; Aniline Compounds; Animals; Anisoles; Benzopyrenes; Biological Assay; Biphenyl Compounds; Bufonidae; Carcinogens; Estrone; Eukaryota; Female; Fluorenes; Humans; In Vitro Techniques; Kynurenic Acid; Male; Mitosis; Naphthalenes; Nicotine; ortho-Aminobenzoates; p-Dimethylaminoazobenzene; Rectum; Urinary Bladder Neoplasms; Xanthurenates

1974
Studies on the effect of reserpine therapy on the functional capacity of the tryptophan-niacin pathway in smoker and non-smoker males.
    Biochemical pharmacology, 1970, Volume: 19, Issue:5

    Topics: Adult; Aminohippuric Acids; Carboxy-Lyases; Catecholamines; Glucuronates; Humans; Isonicotinic Acids; Kynurenic Acid; Kynurenine; Male; Nicotine; Nicotinic Acids; ortho-Aminobenzoates; Pyridines; Pyridoxal Phosphate; Pyridoxine; Reserpine; Smoking; Tryptophan; Xanthurenates

1970
Nicotine-induced excitation of locus coeruleus neurons is blocked by elevated levels of endogenous kynurenic acid.
    Synapse (New York, N.Y.), 2000, Volume: 37, Issue:2

    Topics: Animals; beta-Cyclodextrins; Butyrates; Cyclodextrins; Electrophysiology; Enzyme Inhibitors; Ganglionic Stimulants; Kynurenic Acid; Locus Coeruleus; Male; Neurons; Nicotine; Rats; Rats, Sprague-Dawley

2000
Tryptophan and tyrosine catabolic pattern in neuropsychiatric disorders.
    Neurology India, 2000, Volume: 48, Issue:3

    Topics: Adult; Biogenic Monoamines; Brain Diseases; Brain Neoplasms; Digoxin; Epilepsy, Generalized; Erythrocytes; Fatty Acids, Nonesterified; Female; Glioma; Glycine Agents; Humans; Hydroxymethylglutaryl CoA Reductases; Kynurenic Acid; Magnesium; Male; Microvascular Angina; Middle Aged; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Parkinson Disease; Quinolinic Acid; Schizophrenia; Serum Albumin; Sodium-Potassium-Exchanging ATPase; Strychnine; Tryptophan; Tyrosine; Ubiquinone

2000
Pharmacologically elevated levels of endogenous kynurenic acid prevent nicotine-induced activation of nigral dopamine neurons.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:1

    Topics: Action Potentials; Animals; beta-Cyclodextrins; Butyrates; Cyclodextrins; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Kynurenic Acid; Kynurenine 3-Monooxygenase; Male; Mixed Function Oxygenases; Neurons; Nicotine; Rats; Rats, Sprague-Dawley; Substantia Nigra

2001
The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Oct-01, Volume: 21, Issue:19

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Binding, Competitive; Brain; Cells, Cultured; Choline; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrophysiology; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; N-Methylaspartate; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic

2001
Kynurenate production by cultured human astrocytes.
    Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:1

    Topics: Aminooxyacetic Acid; Astrocytes; Brain; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Glycine; Humans; Immunohistochemistry; Kynurenic Acid; Kynurenine; Leucine; Neuroprotective Agents; Nicotine; Oxaloacetic Acid; Phenylalanine; Pyruvic Acid; Receptors, Nicotinic; Transaminases

2003
Prolonged nicotine administration results in biphasic, brain-specific changes in kynurenate levels in the rat.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:4

    Topics: Acetylcholine; Animals; Brain; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Administration Schedule; Extracellular Fluid; Glutamic Acid; Hippocampus; Kynurenic Acid; Kynurenine; Male; Nicotine; Rats; Rats, Sprague-Dawley; Smoking; Tobacco Use Disorder; Up-Regulation

2005
Long-term exposure to nicotine markedly reduces kynurenic acid in rat brain--in vitro and ex vivo evidence.
    Toxicology and applied pharmacology, 2009, Oct-15, Volume: 240, Issue:2

    Topics: Administration, Oral; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Down-Regulation; Drug Administration Schedule; Injections, Intraperitoneal; Kynurenic Acid; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic; Transaminases

2009
A systemically-available kynurenine aminotransferase II (KAT II) inhibitor restores nicotine-evoked glutamatergic activity in the cortex of rats.
    Neuropharmacology, 2014, Volume: 82

    Topics: Animals; Central Nervous System Agents; Enzyme Inhibitors; Glutamic Acid; Kynurenic Acid; Kynurenine; Male; Membrane Potentials; Microdialysis; Microelectrodes; Nicotine; Nicotinic Agonists; Potassium Chloride; Prefrontal Cortex; Pyrazoles; Rats, Sprague-Dawley; Rats, Wistar; Transaminases

2014
Attenuating Nicotine Reinforcement and Relapse by Enhancing Endogenous Brain Levels of Kynurenic Acid in Rats and Squirrel Monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017, Volume: 42, Issue:8

    Topics: Animals; Cocaine; Dopamine; Isoxazoles; Kynurenic Acid; Male; Nicotine; Nucleus Accumbens; Phenylurea Compounds; Rats; Recurrence; Reinforcement, Psychology; Saimiri; Secondary Prevention; Self Administration; Sulfonamides; Thiazoles

2017
Activation of alpha7 nicotinic and NMDA receptors is necessary for performance in a working memory task.
    Psychopharmacology, 2020, Volume: 237, Issue:6

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; Brain; Kynurenic Acid; Kynurenine; Male; Memory, Short-Term; Nicotine; Psychomotor Performance; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

2020
Kynurenine 3-monooxygenase deficiency induces depression-like behavior via enhanced antagonism of α7 nicotinic acetylcholine receptors by kynurenic acid.
    Behavioural brain research, 2021, 05-07, Volume: 405

    Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Depression; Disease Models, Animal; Kynurenic Acid; Kynurenine 3-Monooxygenase; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex

2021