Page last updated: 2024-08-26

nicotine and isomethyleugenol

nicotine has been researched along with isomethyleugenol in 41 studies

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	23 (56.10)	18.7374
1990's	2 (4.88)	18.2507
2000's	6 (14.63)	29.6817
2010's	8 (19.51)	24.3611
2020's	2 (4.88)	2.80

Authors

Authors	Studies
Seeman, JI; Whidby, JF	1
Acheampont-Mensah, D; Feuer, G	1
Konishi, J; Magata, Y; Ohmomo, Y; Saji, H; Tajima, K; Yamada, Y; Yokoyama, A; Yonekura, Y	1
Crooks, PA; Godin, CS	1
DeMarco, GJ; Howard, PC; McCoy, GD	1
Adams, JD; Hoffmann, D; LaVoie, EJ; Prokopczyk, G	1
Crooks, PA; Cundy, KC; Godin, CS	2
Casida, JE; Lykken, L	1
Westfall, TC	1
Maier, W; Schütte, HR; Stephan, U	1
Frahm, B; Harke, HP; Mauch, A; Schüller, D	1
Cooper, SD; De la Iglesia, FA; Feuer, G; Lumb, G; Miller, DR	1
Bender, AL; Beveridge, DL; Radna, RJ	1
Gorrod, JW; Jenner, P	1
Leete, E	1
Castagnoli, N; Cushman, M	1
Rapoport, H; Rueppel, ML	1
Hedqvist, P	1
Haglid, F	1
Crooks, PA; Cundy, KC	1
Belinsky, SA; Castonguay, A; Grafström, RC; Liu, Y; Sundqvist, K; Tjälve, H	1
Arroo, RR; Baguet, E; Garlick, AP; Girard, S; Lebreton, J; Mesnard, F; Ratcliffe, G; Robins, RJ; Roscher, A	1
ILJIN, GS	1
BOWMAN, ER; MCKENNIS, H; TURNBULL, LB; WADA, E	1
BOWMAN, ER; MCKENNIS, H; TURNBULL, LB	1
Gadani, F; Hempfling, WP; Kalengamaliro, NE; Krauss, MR; Shi, H	1
Bartholomeusz, TA; Felpin, FX; Gillet, F; Lebreton, J; Mesnard, F; Molinié, R; Robins, RJ; Roscher, A	1
Bartholomeusz, TA; Bhogal, RK; Dräger, B; Felpin, FX; Lebreton, J; Mathé-Allainmat, M; Meier, AC; Mesnard, F; Molinié, R; Robins, RJ; Roscher, A	1
Hatton, W; Kwiecień, RA; Lebreton, J; Molinié, R; Paneth, P; Robins, RJ	1
Brown, SA	1
Han, K; Li, D; Wang, Y; Zhan, CG	1
An, B; Hao, D; Lu, Y; Wang, S; Xu, Y; Yang, S; Yin, Y	1
Bush, LP; Cai, B; Chappell, J; Dewey, RE; Siminszky, B	1
Burkey, KO; Bush, LP; Conkling, MA; Fan, L; Holliday, BM; Hung, CY; Kittur, FS; Qiu, J; Roje, S; Sun, K; Tang, S; Xiao, B; Xie, J	1
Bush, LP; Cai, B; Dewey, RE; Jack, AM; Lewis, RS	1
Aagaard, K; Abramovici, AR; Branch, DW; Griffin, E; Lane, RH; Mastrobattista, J; Rehan, VK; Suter, MA	1
Bordey, A; Coman, D; Goldman, D; Heath, CJ; Hsieh, LS; Hyder, F; Jung, Y; Lee, AM; Mineur, YS; Picciotto, MR; Yuan, Q; Zhou, Z	1
Basterretxea, FJ; Caballero-Mancebo, E; Cocinero, EJ; Fernández, JA; Lesarri, A; Pérez, C; Uriarte, I	1
Andrud, KW; Cho, YH; Corsino, P; Habibi, S; Jahn, SC; Kem, WR; Lindstrom, JM; Lu, Z; Lukas, RJ; Rocca, JR; Rouchaud, A; Slavov, S; Soti, F; Xing, H	1
Debnath, A; Hardy, DB; Holloway, AC; Raez-Villanueva, S	1

Reviews

1 review(s) available for nicotine and isomethyleugenol

Article	Year
Alkaloid biosynthesis. Advances in enzymology and related areas of molecular biology, 1969, Volume: 32 Topics: Alkaloids; Animals; Carboxy-Lyases; Indoles; Lyases; Methylation; Mixed Function Oxygenases; Monoamine Oxidase; Nicotine; Nicotinic Acids; Plants; Pyrrolidines; Terpenes; Transaminases; Transferases; Tryptophan	1969

Other Studies

40 other study(ies) available for nicotine and isomethyleugenol

Article	Year
The iodomethylation of nicotine. An unusual example of competitive nitrogen alkylation. The Journal of organic chemistry, 1976, Nov-26, Volume: 41, Issue:24 Topics: Chemical Phenomena; Chemistry; Hydrocarbons, Iodinated; Kinetics; Magnetic Resonance Spectroscopy; Methylation; Nicotine; Nitrogen	1976
Effect of phenobarbital on methyl transfer between methylated drugs and hepatic microsomal phospholipids. Toxicology and applied pharmacology, 1975, Volume: 32, Issue:3 Topics: Animals; Formaldehyde; In Vitro Techniques; Male; Methionine; Methylation; Microsomes, Liver; Nicotine; Pharmaceutical Preparations; Phenobarbital; Phospholipids; Rats	1975
Synthesis of (S)-N-[methyl-11C]nicotine and its regional distribution in the mouse brain: a potential tracer for visualization of brain nicotinic receptors by positron emission tomography. Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:3 Topics: Animals; Brain; Isotope Labeling; Male; Methylation; Mice; Nicotine; Receptors, Nicotinic; Stereoisomerism; Tomography, Emission-Computed	1992
N-methylation of nicotine enantiomers by human liver cytosol. The Journal of pharmacy and pharmacology, 1988, Volume: 40, Issue:2 Topics: Animals; Cytosol; Guinea Pigs; Humans; In Vitro Techniques; Liver; Male; Methylation; Nicotine; Rats; Stereoisomerism	1988
Characterization of hamster liver nicotine metabolism. I. Relative rates of microsomal C and N oxidation. Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16 Topics: Animals; Chromatography, High Pressure Liquid; Cimetidine; Cotinine; Cricetinae; Cyanides; Cysteamine; Male; Mesocricetus; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Nicotine; Oxidation-Reduction; Papain; Peptide Hydrolases; Proadifen	1986
Effect of snuff and nicotine on DNA methylation by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Carcinogenesis, 1987, Volume: 8, Issue:10 Topics: Animals; DNA; Guanine; Liver; Lung; Male; Mathematics; Methylation; Mouth; Nasal Mucosa; Nicotiana; Nicotine; Nitrosamines; Plants, Toxic; Rats; Rats, Inbred F344; Tobacco, Smokeless	1987
Stereospecific in vitro N-methylation of nicotine in guinea pig tissues by an S-adenosylmethionine-dependent N-methyltransferase. Biochemical pharmacology, 1985, Jan-15, Volume: 34, Issue:2 Topics: Animals; Guinea Pigs; In Vitro Techniques; Male; Methylation; Methyltransferases; Nicotine; S-Adenosylmethionine; Stereoisomerism	1985
Remarkable substrate-inhibitor properties of nicotine enantiomers towards a guinea pig lung aromatic azaheterocycle N-methyltransferase. Biochemical and biophysical research communications, 1985, Apr-16, Volume: 128, Issue:1 Topics: Animals; Guinea Pigs; Kinetics; Lung; Methylation; Methyltransferases; Nicotine; S-Adenosylhomocysteine; Stereoisomerism; Substrate Specificity; Time Factors	1985
Metabolism of organic insecticide chemicals. Canadian Medical Association journal, 1969, Jan-25, Volume: 100, Issue:4 Topics: Animals; Carbamates; Chlordan; Chrysanthemum cinerariifolium; DDT; Dieldrin; Diphosphates; Dogs; Drug Synergism; Electron Transport Complex IV; Esterases; Hexachlorocyclohexane; Houseflies; Hydrocarbons, Halogenated; In Vitro Techniques; Insecta; Insecticides; Liver; Methylation; Mice; Microsomes; NADP; Nicotine; Oxidation-Reduction; Parathion; Phosphates; Plants; Pyrrolidines; Radioisotopes; Rats; Rotenone; Sulfoxides	1969
Effect of nicotine and other drugs on the release of 3H-norepinephrine and 3H-dopamine from rat brain slices. Neuropharmacology, 1974, Volume: 13, Issue:8 Topics: Acetylcholine; Animals; Brain; Carbachol; Cerebellum; Cerebral Cortex; Cocaine; Corpus Striatum; Culture Media; Deamination; Dopamine; Edetic Acid; Hexamethonium Compounds; Hypothalamus; In Vitro Techniques; Lidocaine; Methacholine Compounds; Methylation; Morphine; Nicotine; Norepinephrine; Peripheral Nerves; Phenoxybenzamine; Rats; Tritium	1974
[On the biosynthesis of nicotine]. Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1968, Volume: 23, Issue:11 Topics: Amines; Carbon Isotopes; Methylation; Nicotiana; Nicotine; Plants, Toxic; Pyrrolidines	1968
Demethylation of nicotine and cotinine in pigs. Research communications in chemical pathology and pharmacology, 1974, Volume: 9, Issue:4 Topics: Animals; Chromatography, Thin Layer; Mass Spectrometry; Methylation; Nicotine; Pyridines; Pyrrolidinones; Swine	1974
The influence of methyl groups on toxicity and drug metabolism. International journal of clinical pharmacology, therapy and toxicology, 1973, Volume: 7, Issue:1 Topics: Administration, Oral; Amphetamine; Animals; Carbon Isotopes; Coumarins; Enzyme Induction; Female; Humans; Mephobarbital; Methylation; Microscopy, Electron; Microsomes, Liver; Nicotine; Phenobarbital; Phenols; Phospholipids; Pyrazoles; Rats; Structure-Activity Relationship; Tritium	1973
Structural chemistry of cholinergic neural transmission systems. II. A quantum theoretical study of the molecular electronic structure of muscarine, nicotine, acetyl- -methylcholine, acetyl- -methylcholine, acetyl- , -dimethylcholine, and further studies Journal of the American Chemical Society, 1973, Jun-13, Volume: 95, Issue:12 Topics: Acetylcholine; Electron Transport; Mathematics; Methylation; Models, Structural; Molecular Conformation; Nicotine; Parasympatholytics; Parasympathomimetics; Quantum Theory; Structure-Activity Relationship	1973
Comparative in vitro hepatic metabolism of some tertiary N-methyl tobacco alkaloids in various species. Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:3 Topics: Alkaloids; Animals; Chromatography, Gas; Chromatography, Paper; Cricetinae; Cyclic N-Oxides; Dealkylation; Female; Guinea Pigs; In Vitro Techniques; Liver; Male; Methylation; Mice; Nicotiana; Nicotine; Oxidation-Reduction; Piperidines; Plants, Toxic; Pyridines; Pyrroles; Rabbits; Rats; Species Specificity; Stereoisomerism; Time Factors	1973
The condensation of succinic anhydrides with Schiff bases. Scope and mechanism. The Journal of organic chemistry, 1971, Volume: 36, Issue:22 Topics: Amines; Anhydrides; Benzyl Compounds; Chemical Phenomena; Chemistry; Cyclization; Cyclohexylamines; Methods; Methylation; Nicotine; Pyrrolidinones; Schiff Bases; Succinates	1971
Aberrant alkaloid biosynthesis. Formation of nicotine analogs from unnatural precursors in Nicotiana glutinosa. Journal of the American Chemical Society, 1971, Dec-15, Volume: 93, Issue:25 Topics: Carbon Isotopes; Chromatography; Methylation; Nicotine; Plants; Pyrrolidines; Salts; Spectrum Analysis	1971
On the mechanism of depletion of noradrenaline stores by iso-monomethylnicotinium bromide. Acta physiologica Scandinavica, 1970, Volume: 78, Issue:1 Topics: Animals; Cats; Guinea Pigs; Heart; Methylation; Myocardium; Neurosecretion; Nicotine; Norepinephrine; Spleen; Tritium	1970
The methylation of nicotine with methyl-lithium. Acta chemica Scandinavica, 1967, Volume: 21, Issue:2 Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, Gas; Guinea Pigs; Ileum; Indicators and Reagents; Lithium; Magnetic Resonance Spectroscopy; Methylation; Nicotine; Pyridines; Pyrrolidines; Solvents	1967
High-performance liquid chromatographic method for the determination of N-methylated metabolites of nicotine. Journal of chromatography, 1984, Mar-09, Volume: 306 Topics: Animals; Chromatography, High Pressure Liquid; Guinea Pigs; Hydrogen-Ion Concentration; Methylation; Nicotine; Oxidation-Reduction	1984
Metabolism and macromolecular interaction of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in cultured explants and epithelial cells of human buccal mucosa. Carcinogenesis, 1993, Volume: 14, Issue:11 Topics: Autoradiography; Biotransformation; Carcinogens; Cell Division; Cells, Cultured; DNA; Epithelial Cells; Epithelium; Humans; Methylation; Mouth Mucosa; Nicotine; Nitrosamines; Organ Culture Techniques; Protein Binding; Tritium	1993
Evidence for the involvement of tetrahydrofolate in the demethylation of nicotine by Nicotiana plumbaginifolia cell-suspension cultures. Planta, 2002, Volume: 214, Issue:6 Topics: Carbon Radioisotopes; Cells, Cultured; Cysteine; Homocysteine; Magnetic Resonance Spectroscopy; Methionine; Methylation; Models, Chemical; Nicotiana; Nicotine; Plant Extracts; Serine; Tetrahydrofolates	2002
On the participation of nicotine in biological methylation. Pharmaceutisch weekblad, 1957, Nov-02, Volume: 92, Issue:22 Topics: Humans; Methylation; Nicotine	1957
Demethylation in the metabolism of (-)-nicotine in vivo. Nature, 1961, Jun-03, Volume: 190 Topics: Biochemical Phenomena; Humans; Methylation; Nicotine	1961
N-Methylation of nicotine ad cotinine in vivo. The Journal of biological chemistry, 1963, Volume: 238 Topics: Cotinine; Humans; Methylation; Nicotine	1963
Stimulation of nicotine demethylation by NaHCO(3) treatment using greenhouse-grown burley tobacco. Journal of agricultural and food chemistry, 2003, Dec-17, Volume: 51, Issue:26 Topics: Methylation; Nicotiana; Nicotine; Plant Leaves; Sodium Bicarbonate; Temperature	2003
Stereoselectivity of the demethylation of nicotine piperidine homologues by Nicotiana plumbaginifolia cell suspension cultures. Phytochemistry, 2005, Volume: 66, Issue:16 Topics: Alkaloids; Anabasine; Cells, Cultured; Kinetics; Methylation; Molecular Structure; Nicotiana; Nicotine; Pyridines	2005
Nicotine demethylation in Nicotiana cell suspension cultures: N'-formylnornicotine is not involved. Phytochemistry, 2005, Volume: 66, Issue:20 Topics: Alkaloids; Cell Culture Techniques; Cells, Cultured; Cotinine; Gas Chromatography-Mass Spectrometry; Methylation; Nicotiana; Nicotine; Nitrogen Isotopes	2005
Investigation of the mechanism of nicotine demethylation in Nicotiana through 2H and 15N heavy isotope effects: implication of cytochrome P450 oxidase and hydroxyl ion transfer. Archives of biochemistry and biophysics, 2007, Feb-15, Volume: 458, Issue:2 Topics: Deuterium; Hydroxides; Methylation; Models, Chemical; NADPH-Ferrihemoprotein Reductase; Nicotiana; Nicotine; Nitrogen Isotopes; Pyrrolidines	2007
Dr. Stewart A. Brown (PSNA phytochemistry pioneer). Phytochemistry, 2007, Volume: 68, Issue:14 Topics: Awards and Prizes; Biochemistry; Canada; Coumarins; History, 20th Century; Lignin; Methylation; Nicotine; Plants; Societies, Scientific	2007
Fundamental reaction pathways for cytochrome P450-catalyzed 5'-hydroxylation and N-demethylation of nicotine. The journal of physical chemistry. B, 2010, Jul-15, Volume: 114, Issue:27 Topics: Amines; Biocatalysis; Cytochrome P-450 Enzyme System; Hydroxides; Hydroxylation; Iron; Methylation; Models, Molecular; Nicotine; Nitrogen; Protein Conformation; Thermodynamics	2010
Molecular dynamics analysis reveals structural insights into mechanism of nicotine N-demethylation catalyzed by tobacco cytochrome P450 mono-oxygenase. PloS one, 2011, Volume: 6, Issue:8 Topics: Amino Acid Sequence; Amino Acid Substitution; Biocatalysis; Catalytic Domain; Computer Simulation; Cytochrome P-450 Enzyme System; Isoenzymes; Methylation; Models, Molecular; Molecular Dynamics Simulation; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Nicotine; Oxidoreductases, N-Demethylating; Plant Proteins; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Substrate Specificity	2011
Enantioselective demethylation of nicotine as a mechanism for variable nornicotine composition in tobacco leaf. The Journal of biological chemistry, 2012, Dec-14, Volume: 287, Issue:51 Topics: Alkaloids; Biosynthetic Pathways; Cytochrome P-450 Enzyme System; Kinetics; Methylation; Models, Biological; Nicotiana; Nicotine; Plant Leaves; Plant Proteins; Stereoisomerism; Substrate Specificity	2012
Alteration of the alkaloid profile in genetically modified tobacco reveals a role of methylenetetrahydrofolate reductase in nicotine N-demethylation. Plant physiology, 2013, Volume: 161, Issue:2 Topics: Alkaloids; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cytochrome P-450 Enzyme System; DNA, Complementary; Folic Acid; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Immunoblotting; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Molecular Sequence Data; Nicotiana; Nicotine; Plant Leaves; Plant Proteins; Plants, Genetically Modified; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid	2013
(R)-nicotine biosynthesis, metabolism and translocation in tobacco as determined by nicotine demethylase mutants. Phytochemistry, 2013, Volume: 95 Topics: Biological Transport; Cytochrome P-450 Enzyme System; Methylation; Mutation; Nicotiana; Nicotine; Plant Leaves; Plant Proteins; Plant Roots	2013
In utero nicotine exposure epigenetically alters fetal chromatin structure and differentially regulates transcription of the glucocorticoid receptor in a rat model. Birth defects research. Part A, Clinical and molecular teratology, 2015, Volume: 103, Issue:7 Topics: Acetylation; Animals; Chromatin; Female; Fetus; Gene Expression Regulation, Developmental; Male; Maternal Exposure; Methylation; Models, Animal; Nicotine; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; RNA Splicing; Transcription, Genetic	2015
An epigenetic mechanism mediates developmental nicotine effects on neuronal structure and behavior. Nature neuroscience, 2016, Volume: 19, Issue:7 Topics: Animals; DNA-Binding Proteins; Epigenesis, Genetic; Histone-Lysine N-Methyltransferase; Histones; Methylation; Mice, Inbred C57BL; Nicotine; Nuclear Proteins; Promoter Regions, Genetic; Transcription Factors	2016
Structural Studies of Nicotinoids: Cotinine versus Nicotine. Chemistry (Weinheim an der Bergstrasse, Germany), 2017, May-29, Volume: 23, Issue:30 Topics: Cotinine; Hydrogen Bonding; Methylation; Models, Molecular; Molecular Conformation; Nicotine; Nicotinic Agonists; Pyridines; Pyrrolidinones; Stereoisomerism; Thermodynamics	2017
A Methyl Scan of the Pyrrolidinium Ring of Nicotine Reveals Significant Differences in Its Interactions with Molecular pharmacology, 2020, Volume: 98, Issue:2 Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Binding Sites; Male; Methylation; Molecular Docking Simulation; Molecular Structure; Nicotine; Pyridines; Rats; Receptors, Nicotinic; Structure-Activity Relationship; Xenopus laevis	2020
Prenatal nicotine exposure leads to decreased histone H3 lysine 9 (H3K9) methylation and increased Journal of developmental origins of health and disease, 2022, Volume: 13, Issue:2 Topics: Animals; Female; Histones; Lysine; Methylation; Nicotine; Pancreas; Pregnancy; Rats; Src Homology 2 Domain-Containing, Transforming Protein 1	2022