nicotine has been researched along with idazoxan in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Brasch, H | 1 |
| Loiacono, RE; Mitchelson, FJ | 1 |
| Simson, PE; Weiss, JM | 1 |
| Dusting, GJ; Li, DM | 1 |
| Levin, ED; Timofeeva, OA | 1 |
| Chopde, CT; Gahane, AY; Kotagale, NR; Taksande, BG; Ugale, RR | 1 |
| Markou, A; Semenova, S | 1 |
11 other study(ies) available for nicotine and idazoxan
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
No influence of prejunctional alpha 2-adrenoceptors on the effects of nicotine and tyramine in guinea-pig atria.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Electric Stimulation; Guinea Pigs; Heart; Idazoxan; In Vitro Techniques; Male; Myocardial Contraction; Nicotine; Receptors, Adrenergic, alpha; Tetrodotoxin; Tyramine | 1991 |
Effect of nicotine and tacrine on acetylcholine release from rat cerebral cortical slices.
Topics: Acetylcholine; Aminoacridines; Animals; Atropine; Cerebral Cortex; Dioxanes; Electric Stimulation; Female; Idazoxan; In Vitro Techniques; Male; Nerve Endings; Nicotine; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Tacrine; Tubocurarine | 1990 |
Alpha-2 receptor blockade increases responsiveness of locus coeruleus neurons to excitatory stimulation.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Idazoxan; Injections, Intravenous; Locus Coeruleus; Male; Neurons; Nicotine; Pain; Physical Stimulation; Rats; Rats, Inbred Strains; Yohimbine | 1987 |
Catecholamine release and potentiation of thromboxane A2 production by nicotine in the greyhound.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Catecholamines; Dioxanes; Dogs; Epinephrine; Female; Heart Rate; Idazoxan; Imidazoles; In Vitro Techniques; Ketanserin; Male; Nicotine; Phenoxybenzamine; Piperidines; Thromboxane A2; Vasoconstriction | 1986 |
Idazoxan blocks the nicotine-induced reversal of the memory impairment caused by the NMDA glutamate receptor antagonist dizocilpine.
Topics: Adrenergic alpha-Antagonists; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Idazoxan; Maze Learning; Memory; Memory Disorders; Memory, Short-Term; Nicotine; Nicotinic Agonists; Norepinephrine; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Synaptic Transmission | 2008 |
Repeated agmatine treatment attenuates nicotine sensitization in mice: modulation by alpha2-adrenoceptors.
Topics: Agmatine; Animals; Arginine; Biguanides; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Eflornithine; Enzyme Inhibitors; Guanidines; Idazoxan; Male; Mice; Motor Activity; Nicotine; Receptors, Adrenergic, alpha-2; Yohimbine | 2010 |
The alpha2 adrenergic receptor antagonist idazoxan, but not the serotonin-2A receptor antagonist M100907, partially attenuated reward deficits associated with nicotine, but not amphetamine, withdrawal in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Amphetamine; Animals; Brain; Dihydro-beta-Erythroidine; Electrodes, Implanted; Fluorobenzenes; Ganglionic Stimulants; Idazoxan; Male; Nicotine; Piperidines; Rats; Rats, Wistar; Receptors, Nicotinic; Reward; Serotonin Antagonists; Substance Withdrawal Syndrome | 2010 |