nicotine has been researched along with glutamic acid in 199 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (5.03) | 18.7374 |
| 1990's | 34 (17.09) | 18.2507 |
| 2000's | 87 (43.72) | 29.6817 |
| 2010's | 60 (30.15) | 24.3611 |
| 2020's | 8 (4.02) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K | 1 |
| Hashim, A; Lajtha, A; Sershen, H; Toth, E; Vizi, ES | 1 |
| Beart, PM; Marley, PD; Mercer, LD; O'Shea, RD | 1 |
| Lahiri, S; Spergel, D; Wilson, DF | 1 |
| Iwamoto, ET | 1 |
| Aguirre, JA; Fuxe, K; Méndez-Franco, J; Pérez de la Mora, M; Salceda, R | 1 |
| Mehta, AR; Ravishankar, GA | 1 |
| Engberg, G | 1 |
| Frazier, DT; Taylor, RF | 1 |
| Bland, BH; Konopacki, J; Roth, SH | 1 |
| Kanje, M; Lazarewicz, JW | 1 |
| Barker, JL; Mathers, DA | 1 |
| Kerkerian, L; Nieoullon, A | 1 |
| Brien, J; Jhamandas, K; Marien, M | 1 |
| Agapova, VN; Godukhin, OV; Selifanova, OV | 1 |
| Beaujouan, JC; Glowinski, J; Torrens, Y | 1 |
| Akaike, A; Kimura, J; Shimohama, S; Tamura, Y; Yokota, T | 1 |
| Devay, P; Gelber, S; Heath, MJ; McGehee, DS; Role, LW | 1 |
| Spergel, D | 1 |
| Appalsamy, M; Mosqueda-Garcia, R; Robertson, D | 1 |
| Bickler, PE; Cardone, C; Szenohradszky, J; Yost, S | 1 |
| Jayaraman, A; Kiba, H | 1 |
| Akaike, A; Kimura, J; Shimohama, S | 1 |
| Garcia-Munoz, M; Groves, PM; Patino, P; Young, SJ | 1 |
| McGehee, DS; Role, LW | 1 |
| Abdulla, FA; Calaminici, M; Gray, JA; Sinden, JD; Stephenson, JD; Wonnacott, S | 1 |
| Dani, JA; Gray, R; Radcliffe, KA; Rajan, AS; Yakehiro, M | 1 |
| Bordey, A; Feltz, P; Trouslard, J | 1 |
| Fu, WM; Liu, JJ | 1 |
| Gershon, MD; Kirchgessner, AL; Liu, MT; Rothstein, JD | 1 |
| Akaike, A; Kaneko, S; Kimura, J; Kochiyama, H; Kume, T; Maeda, T; Shimohama, S | 1 |
| González, MP; Herrero, MT; Oset-Gasque, MJ; Vicente, S | 1 |
| Koizumi, S; Moriyama, Y; Ogura, A; Yamada, H; Yamaguchi, A | 1 |
| Mendelowitz, D | 1 |
| Dani, JA; Radcliffe, KA | 1 |
| Felipo, V; Grisolía, S; Llansola, M; Miñana, MD; Montoliu, C | 1 |
| Dalack, GW; Healy, DJ; Meador-Woodruff, JH | 1 |
| Ansaldo, MA; Fedele, E; Raiteri, M; Varnier, G | 1 |
| Clarke, PB; Gioanni, Y; Lepousé, C; Rougeot, C; Thierry, AM; Vidal, C | 1 |
| French, SJ; Horner, CH; Humby, T; Rattray, M; Sofroniew, MV | 1 |
| Alvarez, RM; Cárdenas, AM; Caviedes, P; Caviedes, R; Cortés, MP; Rapoport, SI; Rodríguez, MP; Shimahara, T; Wei, W | 1 |
| Dani, JA; Fisher, JL; Gray, R; Radcliffe, KA | 1 |
| Damaj, MI; Dukat, M; Glassco, W; Martin, BR | 1 |
| Gallardo, KA; Oliff, HS | 1 |
| Berger, SP; Fox, L; Ho, LB; Reid, MS | 1 |
| Bernardi, G; Berretta, N; Grillner, P; Mercuri, NB; Svensson, TH | 1 |
| Ito, E; Tojima, T | 1 |
| Dretchen, KL; Ferreira, M; Gillis, RA; Kellar, KJ; Singh, A | 1 |
| Brower, VG; Fu, Y; Gao, W; Matta, SG; Sharp, BM | 1 |
| Antonelli, T; Beani, L; Bianchi, C; Marani, L; Tomasini, MC | 1 |
| Dajas-Bailador, FA; Lima, PA; Wonnacott, S | 1 |
| Fagerquist, MV; Hertel, P; Nomikos, GG; Panagis, G; Schilström, B; Svensson, TH; Zhang, X | 1 |
| Choi, WJ; Lim, DK; Park, SH | 1 |
| Regehr, WG; Vogt, KE | 1 |
| Arce, C; González, MP; López, E; Oset-Gasque, MJ; Vicente, S | 1 |
| Akaike, A; Honda, K; Kihara, T; Kume, T; Nakamizo, T; Sawada, H; Shibasaki, H; Shimohama, S | 1 |
| Zhou, ZJ | 1 |
| Barazangi, N; Role, LW | 1 |
| Girod, R; Role, LW | 1 |
| Amano, H; Amano, T; Matsubayashi, H; Sasa, M | 1 |
| Cherubini, E; Maggi, L; Sher, E | 1 |
| Lennox, JR; Rapoport, H; Turner, SC | 1 |
| Kim, HS; Lim, DK | 2 |
| Gauglitz, S; Pflüger, HJ | 1 |
| Hilgenberg, LG; Ho, KD; Lee, D; O'Dowd, DK; Smith, MA | 1 |
| Engberg, G; Erhardt, S; Schwieler, L | 1 |
| Hsieh, CY; Leslie, FM; Metherate, R | 1 |
| Andresen, MC; Evans, C; Irnaten, M; K Chang, KS; Mendelowitz, D; Venkatesan, P; Wang, J | 1 |
| Keath, JR; Mansvelder, HD; McGehee, DS | 1 |
| Albuquerque, EX; Alkondon, M; Aracava, Y; Eisenberg, HM; Maelicke, A; Pereira, EF; Santos, MD | 1 |
| Kamel, D; Kay, TS; Krentz, L; Meshul, CK; Moore, C | 1 |
| Sorimachi, M; Wakomori, M; Yamagami, K | 1 |
| Amerio, G; Frøen, JF; Saugstad, OD; Stray-Pedersen, B | 1 |
| Brussaard, AB; de Rover, M; Kits, KS; Lodder, JC; Schoffelmeer, AN | 1 |
| Berg, DK; Chang, KT; Hu, M; Liu, QS | 1 |
| Markus, RP; Reno, LA; Santos, JM; Zago, W | 1 |
| Sharma, G; Vijayaraghavan, S | 1 |
| BYERRUM, RU; LAMBERTS, BL | 1 |
| Fitzsimonds, RM; Krueger, SR; Picciotto, MR; Stevens, TR | 1 |
| Cohen, RW; Hildebrandt, IJ; Termeer, JL; Toledo, D | 1 |
| Markus, RP; Reno, LA; Zago, W | 1 |
| Gu, Y; Qhobosheane, M; Tan, W; Wu, D | 1 |
| Coulibaly, SF; Linn, CL; Linn, DM; Thompson, SA; Wehrwein, E | 1 |
| Bouairi, E; Evans, C; Gold, A; Huang, ZG; Mendelowitz, D; Wang, X | 1 |
| Baviera, M; Calcagno, E; Carli, M; Ceglia, I; Invernizzi, RW; Renoldi, G | 1 |
| Albuquerque, EX; Rassoulpour, A; Schwarcz, R; Wu, HQ | 1 |
| Kanno, T; Nagata, T; Nishizaki, T; Tanaka, A; Yaguchi, T; Yamamoto, S | 1 |
| Akaike, A; Kanki, R; Kawamata, J; Kihara, T; Nakamizo, T; Sawada, H; Shimohama, S; Yamashita, H | 1 |
| Domino, EF; Fukumoto, D; Kakiuchi, T; Miyasato, K; Nishiyama, S; Tsukada, H | 1 |
| Barik, J; Wonnacott, S | 1 |
| Aoki, C; Levy, RB; Reyes, AD | 1 |
| Grilli, M; Marchi, M; Parodi, M; Patti, L; Raiteri, L; Raiteri, M | 1 |
| Chang, CT; Liao, WN; Wang, BW; Wang, SJ | 1 |
| Carrión, M; Delgado-García, JM; Rodríguez-Moreno, A | 1 |
| Ding, JH; Hu, G; Li, Z; Liu, Q; Liu, SY; Wu, J | 1 |
| Adriani, W; Dambinova, S; Granstrem, O; Izykenova, G; Laviola, G; Shumilina, M | 1 |
| Bouairi, E; Dergacheva, O; Gorini, C; Huang, ZG; Kamendi, H; McIntosh, JM; Mendelowitz, D; Stephens, C; Wang, X | 1 |
| DeChon, J; Hu, G; Hu, J; Liu, Q; Wu, J; Yan, KC | 1 |
| Al-Rejaie, S; Dar, MS | 1 |
| De Witte, P; Dravolina, O; Lallemand, F; Ward, RJ | 1 |
| Badawy, AA; Huebner, A; Krimphove, M; Morgenstern, R; Saellstroem Baum, S; Spies, CD | 1 |
| Allen, DD; Cárdenas, AM; Caviedes, P; Caviedes, R; de Saint Pierre, M; Opazo, P; Saud, K; Segura-Aguilar, J | 1 |
| Capsoni, S; Cattaneo, A; Cherubini, E; Rosato-Siri, M; Sola, E | 1 |
| Lamanauskas, N; Nistri, A | 2 |
| Jia, Y; Sumikawa, K; Wong, JK; Yamazaki, Y | 1 |
| Cherubini, E; Le Magueresse, C | 1 |
| DiFranza, JR; Wellman, RJ | 1 |
| Ferrari, MF; Fior-Chadi, DR | 1 |
| Heath, CJ; Picciotto, MR; Steiner, RC | 1 |
| Gass, JT; Olive, MF | 1 |
| Flatscher-Bader, T; Landis, N; Wilce, PA; Zuvela, N | 1 |
| Barrett, LE; Iacoviello, MP; Keath, JR; Mansvelder, HD; McGehee, DS | 1 |
| Tizabi, Y | 1 |
| Mineur, YS; Picciotto, MR; Vieyra-Reyes, P | 1 |
| Jiang, L; Role, LW | 1 |
| Decker, MW; Man, K; Parikh, V; Sarter, M | 1 |
| Chen, H; Sharp, BM; Wang, F | 1 |
| Du, C; Hancock, M; Mertz, M; Role, LW; Talmage, DA; Zhong, C | 1 |
| Andresen, JH; Saugstad, OD | 1 |
| Fukuma, G; Hase, K; Hirose, S; Kaneko, S; Kijima, H; Kishi, A; Kojima, T; Mitsudome, A; Miura, Y; Mori, F; Ohno, H; Okada, M; Saito, R; Sato, A; Takahara, T; Takano, Y; Tomiyama, M; Ueno, S; Wakabayashi, K; Yoshida, S; Zhu, G | 1 |
| Ascher, P; Lamotte d'Incamps, B | 1 |
| Kalivas, PW; Knackstedt, LA | 1 |
| Brand, A; Landau, VJ; LaVinka, PC; Park, TJ; Wirtshafter, D | 1 |
| Shimohama, S | 1 |
| Bancila, V; Bloc, A; Cordeiro, JM; Dunant, Y | 1 |
| Feldman, JL; Shao, XM | 1 |
| Jin, GZ; Wu, J; Xiao, C; Yang, KC; Ye, JH; Zhou, CY | 1 |
| Ishibashi, M; Kohlmeier, KA; Leonard, CS | 1 |
| Alexander, K; Bruno, JP; Gash, CR; Gerhardt, GA; Huettl, P; Konradsson-Geuken, A; Pomerleau, F | 1 |
| Gong, CL; Kuo, JS; Lee, TJ; Leung, YM; Lin, NN | 1 |
| Cai, H; Lester, HA; McIntosh, JM; McKinney, S; Nashmi, R; Xiao, C | 1 |
| Huang, LT; Lodge, D; Sherwood, JL; Sun, YJ; Wang, Y | 1 |
| Chen, H; Matta, SG; Sharp, BM; Wu, X; Yu, G | 1 |
| Fadel, J; Pasumarthi, RK | 1 |
| Jin, Y; Wang, H; Wu, J; Yang, K | 1 |
| Gao, M; Jin, Y; Lukas, RJ; Wu, J; Yang, K; Zhang, D | 1 |
| Fregosi, RF; Fuglevand, AJ; Levine, RB; Pilarski, JQ; Wakefield, HE | 1 |
| Feng, L; Gusev, AG; Kalappa, BI; Kem, WR; Uteshev, VV | 1 |
| Evins, AE; Fava, M; Janes, AC; Jensen, JE; Kaufman, MJ; Mashhoon, Y; Pachas, G; Prescot, AP; Renshaw, PF | 1 |
| Biundo, F; Cavallero, A; Govoni, S; Grilli, M; Lanni, C; Marchi, M; Mura, E; Olivero, G; Preda, S; Salamone, A; Zappettini, S | 1 |
| Grilli, M; Marchi, M; Olivero, G; Pittaluga, A; Zappettini, S | 1 |
| Chen, M; Maleski, JJ; Nguyen, HT; Sawmiller, DR; Wu, Q | 1 |
| Berg, DK; Duan, J; Gounko, NV; Liu, Z; Lozada, AF; Massey, KA; Wang, X | 2 |
| Patel, AB; Shameem, M | 1 |
| Owaisat, S; Raffa, RB; Rawls, SM | 1 |
| Buczynski, MW; Natividad, LA; O'Dell, LE; Parsons, LH; Torres, OV | 1 |
| Conn, PJ; Cosford, ND; D'Souza, MS; Dahl, R; Dhanya, RP; Mangravita-Novo, A; Markou, A; Nickols, HH; Semenova, S; Sheffler, DJ; Sidique, S; Smith, LH; Yang, L | 1 |
| Galarraga, E; Galindo-Charles, L; Garduño, J; Hernandez-Lopez, S; Jiménez-Rodríguez, J; Mihailescu, S; Tapia, D | 1 |
| Binkert, CA; Brügger, M; Froehlich, JM; Graf, N; Grosshans, M; Gutzeit, A; Herdener, M; Hergan, K; Kos, S; Meier, D; Mutschler, J; Reischauer, C; Schubert, T; Straka, M; Sutter, R | 1 |
| Chen, SR; Cheng, PW; Cheng, WH; Hong, LZ; Tseng, CJ; Wang, LL | 1 |
| Iwamoto, K; Linn, CL; Linn, DM; Mata, D | 1 |
| Amadeo, A; Aracri, P; Becchetti, A; Fascio, U; Pasini, ME | 1 |
| Alajaji, M; Bowers, MS; Damaj, MI; Knackstedt, L | 1 |
| Albuquerque, EX; Alkondon, M; Pereira, EF | 1 |
| D'Souza, MS; Markou, A | 2 |
| Grunnet, M; Grupe, M; Jensen, AA; Paolone, G; Sandager-Nielsen, K; Sarter, M | 1 |
| Chen, H; Matta, SG; Roguski, EE; Sharp, BM | 1 |
| Gardner, PD; Liu, L; Pang, X; Tapper, AR; Zhao-Shea, R | 1 |
| Govoni, S; Grilli, M; Marchi, M; Mura, E; Olivero, G; Preda, S; Salamone, A; Zappettini, S | 1 |
| Harano, S; Hisaoka-Nakashima, K; Idenoshita, Y; Morioka, N; Nakamura, Y; Nakata, Y; Tokuhara, M; Zhang, FF | 1 |
| Do, SH; Hur, W; Lim, YJ; Yoon, HJ; Zuo, Z | 1 |
| Berg, DK; Gómez-Varela, D; Halff, AW; John, D | 1 |
| Chen, M; Nguyen, HT | 1 |
| Gritton, H; Johnson, DE; Koshy Cherian, A; Kozak, R; Sarter, M; Young, D | 1 |
| Falasca, S; Khani, A; Kretz, R; Petruzziello, F; Rainer, G; Ranc, V; Zhang, X | 1 |
| Damborsky, JC; Griffith, WH; Winzer-Serhan, UH | 1 |
| Kohlmeier, KA; McNair, LF | 1 |
| Clementi, F; Gotti, C; Pistillo, F; Zoli, M | 1 |
| Deshpande, P; Henderson, BJ; Lester, HA; McKinney, SL; Miwa, JM; Wang, Y; Xiao, C | 1 |
| Aoyama, Y; Hattori, T; Hiramatsu, M; Kim, HC; Mamiya, T; Mouri, A; Nabeshima, T; Nagai, T; Sakakibara, N; Shimato, A; Soh, Y; Toriumi, K; Ueda, E; Yamada, K | 1 |
| Deehan, GA; Hauser, SR; Knight, CP; McBride, WJ; Rodd, ZA; Toalston, JE; Truitt, WA; Waeiss, RA | 1 |
| Harano, S; Hisaoka-Nakashima, K; Idenoshita, Y; Morioka, N; Nakata, Y; Tokuhara, M; Zhang, FF | 1 |
| Al-Rejaie, SS; Alasmari, F; AlSharari, SD; Sari, Y | 1 |
| Corsini, S; Nistri, A; Tortora, M | 2 |
| Cholanian, M; Fregosi, RF; Levine, RB; Powell, GL | 1 |
| Bekheet, G; Howe, WM; Kozak, R; Young, DA | 1 |
| Bello, NT; Bierut, LJ; Goate, A; Halikere, A; Hart, RP; Li, G; Moore, JC; Oni, EN; Pang, ZP; Swerdel, MR; Tischfield, JA; Toro-Ramos, AJ; Verpeut, JL | 1 |
| Baumann, VJ; Koch, U | 1 |
| Carcoba, LM; Flores, RJ; Natividad, LA; O'Dell, LE | 1 |
| Chang, S; Cho, HW; Choe, ES; Kim, HY; Kim, J; Lee, DK; Oh, JH; Ryu, IS; Seo, JW; Seo, SY; Shim, I; Yang, JH; Yoon, SS | 1 |
| Kohlmeier, KA; Polli, FS | 1 |
| Appleyard, SM; Page, SJ; Zhu, M | 1 |
| Allen, NP; Del Franco, AP; Gipson, CD; Goenaga, J; Leyrer-Jackson, JM; McClure, EA; Namba, MD; Olive, MF; Piña, J; Powell, GL; Schwartz, D; Spencer, S; Stankeviciute, N | 1 |
| Mabandla, MV; Rakgantsho, C | 1 |
| Caffino, L; Cervo, L; Di Clemente, A; Fumagalli, F; Giannotti, G; Marzo, CM; Moro, F | 1 |
| Choe, ES; Kim, J; Kim, S; Ryu, IS; Sohn, S; Yang, JH | 1 |
| Garcia-Keller, C; Gipson, CD; Goenaga, JG; Hogue, IB; Kupchik, YM; Namba, MD; Powell, GL; Spencer, SM; Vicino, IA | 1 |
| Diwadkar, VA; Greenwald, MK; Khatib, D; Stanley, JA; Woodcock, EA | 1 |
| Cole, RD; Gould, TJ; Kutlu, MG; Matchanova, A; Parikh, V; Zimmerman, M | 1 |
| Abulseoud, OA; Caparelli, EC; Castillo, J; Fedota, J; Gu, H; Nam, HW; Ross, TJ; Schleyer, B; Stein, E; Tennekoon, M; Yang, Y | 1 |
| Foster Olive, M; Gipson, CD; Leyrer-Jackson, JM; McCallum, J; Piña, JA | 1 |
| Carcoba, LM; DeBiasi, M; Mendez, IA; O'Dell, LE; Ortegon, S; Uribe, KP | 1 |
| Stratilov, VA; Tyulkova, EI; Vetrovoy, OV | 1 |
16 review(s) available for nicotine and glutamic acid
| Article | Year |
|---|---|
Chemically induced ion channels in nerve cell membranes.
Topics: Acetylcholine; Animals; Barbiturates; Benzodiazepines; Cell Membrane; Cells, Cultured; Central Nervous System; Convulsants; Culture Techniques; Decapodiformes; Electricity; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Autonomic; Ganglia, Sympathetic; Glutamates; Glutamic Acid; Glycine; Ion Channels; Mollusca; Muscarine; Neurons; Nicotine; Pentobarbital; Spinal Cord; Vertebrates | 1982 |
The striatonigral substance P pathway and dopaminergic mechanisms.
Topics: Animals; Axonal Transport; Cells, Cultured; Corpus Striatum; Dopamine; Electrophysiology; Embryo, Mammalian; Embryo, Nonmammalian; Glutamates; Glutamic Acid; Kinetics; Mesencephalon; Methionine; Neural Pathways; Neurons; Nicotine; Potassium; Receptors, Cell Surface; Receptors, Neurokinin-1; Substance P; Substantia Nigra | 1982 |
Presynaptic ionotropic receptors.
Topics: Animals; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Ion Channel Gating; Nicotine; Presynaptic Terminals; Receptors, Cell Surface | 1996 |
Nicotine dependence in schizophrenia: clinical phenomena and laboratory findings.
Topics: Adult; Animals; Bungarotoxins; Comorbidity; Dopamine; Drug Interactions; Glutamic Acid; Humans; Ion Channel Gating; Middle Aged; Models, Biological; Models, Neurological; Nicotine; Prevalence; Rats; Receptors, Dopamine; Receptors, Glutamate; Receptors, Nicotinic; Schizophrenia; Schizophrenic Psychology; Self Medication; Smoking; Tobacco Use Disorder | 1998 |
The effect of nicotine on developing brain catecholamine systems.
Topics: Animals; Brain; Catecholamines; Child; Dopamine; Female; Glutamic Acid; Humans; Locomotion; Male; Maternal Exposure; Nicotine; Norepinephrine; Pregnancy; Rats; Receptors, Nicotinic; Sex Factors; Stress, Physiological | 1999 |
The function of the cholinergic system in the developing mammalian retina.
Topics: Aging; Animals; Animals, Newborn; Cholinergic Fibers; Electrophysiology; Glutamic Acid; Mammals; Muscarine; Nicotine; Receptors, Neurotransmitter; Retina; Synaptic Transmission | 2001 |
Sensitization to nicotine: how the animal literature might inform future human research.
Topics: Adaptation, Physiological; Animals; Brain; Conditioning, Psychological; Dopamine; Drug Tolerance; Endorphins; Female; Ganglionic Stimulants; Glutamic Acid; Homeostasis; Humans; Locomotion; Narcotics; Nicotine; Norepinephrine; Serotonin; Sex Factors | 2007 |
Glutamatergic substrates of drug addiction and alcoholism.
Topics: Alcoholism; Amphetamines; Animals; Cannabinoids; Cocaine; Disease Models, Animal; Extinction, Psychological; Glutamic Acid; Humans; Narcotics; Neuronal Plasticity; Nicotine; Substance-Related Disorders; Synapses; Synaptic Transmission | 2008 |
Nicotine and nicotinic system in hypoglutamatergic models of schizophrenia.
Topics: Animals; Disease Models, Animal; Electrophysiology; Glutamic Acid; Humans; Nicotine; Receptors, Nicotinic; Schizophrenia; Schizophrenic Psychology; Smoking | 2007 |
Glutamate and reinstatement.
Topics: Animals; Behavior, Addictive; Brain; Cocaine; Ethanol; Glutamic Acid; Heroin; Humans; Nicotine; Receptors, Glutamate; Recurrence; Substance-Related Disorders; Synaptic Transmission | 2009 |
Nicotinic receptor-mediated neuroprotection in neurodegenerative disease models.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Drug Synergism; Galantamine; Glutamic Acid; Motor Neurons; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Oxidopamine; Parkinson Disease, Secondary; Phosphatidylinositol 3-Kinases; Rats; Receptors, Nicotinic; Rotenone; Signal Transduction; Spinal Cord | 2009 |
Central cholinergic regulation of respiration: nicotinic receptors.
Topics: Animals; Drug Delivery Systems; Female; Glutamic Acid; Humans; Infant, Newborn; Nicotine; Nicotinic Agonists; Pregnancy; Receptors, Nicotinic; Respiration; Respiratory Center; Sleep Apnea Syndromes; Sudden Infant Death | 2009 |
The "stop" and "go" of nicotine dependence: role of GABA and glutamate.
Topics: Animals; Behavior, Animal; Brain; Conditioning, Psychological; Dopamine; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Limbic System; Nicotine; Nicotinic Antagonists; Receptors, Glutamate; Reinforcement, Psychology; Smoking Cessation; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2013 |
Nicotinic, glutamatergic and dopaminergic synaptic transmission and plasticity in the mesocorticolimbic system: focus on nicotine effects.
Topics: Animals; Cerebral Cortex; Dopamine; Glutamic Acid; Humans; Limbic System; Nicotine; Synaptic Transmission | 2015 |
Targeting glutamate homeostasis for potential treatment of nicotine dependence.
Topics: Animals; Excitatory Amino Acid Antagonists; Glutamic Acid; Homeostasis; Humans; Nicotine; Tobacco Use Disorder; Up-Regulation | 2016 |
Interactions of Glutamatergic Neurotransmission and Brain-Derived Neurotrophic Factor in the Regulation of Behaviors after Nicotine Administration.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior; Brain-Derived Neurotrophic Factor; GABAergic Neurons; Glutamic Acid; Hippocampus; Humans; Nerve Growth Factors; Nicotine; Receptor, trkB; Receptors, Glutamate; Signal Transduction; Synaptic Transmission | 2019 |
2 trial(s) available for nicotine and glutamic acid
| Article | Year |
|---|---|
Insula-specific H magnetic resonance spectroscopy reactions in heavy smokers under acute nicotine withdrawal and after oral nicotine substitution.
Topics: Administration, Oral; Adult; Behavior, Addictive; Carbon Monoxide; Case-Control Studies; Cerebral Cortex; Functional Neuroimaging; Glutamic Acid; Glutamine; Humans; Inositol; Male; Middle Aged; Nicotine; Smoking; Substance Withdrawal Syndrome; Tobacco Use Cessation Devices | 2013 |
Short-term nicotine deprivation alters dorsal anterior cingulate glutamate concentration and concomitant cingulate-cortical functional connectivity.
Topics: Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Nicotine; Tobacco Use Disorder | 2020 |
181 other study(ies) available for nicotine and glutamic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship | 2010 |
Effect of nicotine on extracellular levels of neurotransmitters assessed by microdialysis in various brain regions: role of glutamic acid.
Topics: Animals; Biogenic Monoamines; Brain; Corpus Striatum; Dialysis; Dopamine; Glutamates; Glutamic Acid; Male; Neurotransmitter Agents; Nicotine; Permeability; Rats; Rats, Inbred Strains | 1992 |
Biochemical, autoradiographic and functional studies on a unique glutamate binding site in adrenal gland.
Topics: Adrenal Glands; Animals; Autoradiography; Binding Sites; Binding, Competitive; Catecholamines; Cattle; Dogs; Female; Glutamates; Glutamic Acid; Guinea Pigs; Kinetics; Kynurenic Acid; Male; Nicotine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1992 |
Dependence of carotid chemosensory responses on metabolic substrates.
Topics: Amino Acids; Animals; Blood Glucose; Carotid Body; Cats; Chemoreceptor Cells; Glucose; Glutamates; Glutamic Acid; Hypoxia; Nicotine; Perfusion | 1992 |
Characterization of the antinociception induced by nicotine in the pedunculopontine tegmental nucleus and the nucleus raphe magnus.
Topics: Analgesia; Animals; Dioxolanes; Glutamates; Glutamic Acid; Hemicholinium 3; Male; Mecamylamine; Medulla Oblongata; Naloxone; Nicotine; Procainamide; Raphe Nuclei; Rats; Rats, Inbred Strains; Reflex | 1991 |
Neurochemical effects of nicotine on glutamate and GABA mechanisms in the rat brain.
Topics: Animals; Brain; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Male; Neurons; Nicotine; Rats; Rats, Inbred Strains; Tritium | 1991 |
Glutamic acid-induced shoot differentiation in tobacco callus tissues and changes in nicotine content and in activities of aminotransferases, ornithine transcarbamylase, and arginase.
Topics: Arginase; Cells, Cultured; Culture Media; Glutamates; Glutamic Acid; Kinetics; Nicotiana; Nicotine; Ornithine Carbamoyltransferase; Ornithine-Oxo-Acid Transaminase; Plants, Toxic; Transaminases; Tyrosine Transaminase | 1991 |
Nicotine induced excitation of locus coeruleus neurons is mediated via release of excitatory amino acids.
Topics: Action Potentials; Amino Acids; Animals; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Kynurenic Acid; Locus Coeruleus; Male; Neurons; Nicotine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Effect of nicotine and acetylcholine on crustacean muscle membrane potential.
Topics: Acetylcholine; Animals; Astacoidea; Glutamates; Glutamic Acid; Membrane Potentials; Muscles; Nicotine | 1986 |
Evidence that activation of in vitro hippocampal theta rhythm only involves muscarinic receptors.
Topics: Animals; Carbachol; Dopamine; Electroencephalography; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Nicotine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Serotonin; Theta Rhythm | 1988 |
Effects of neurotransmitters on calcium efflux from cultured glioma cells.
Topics: Astrocytoma; Atropine; Calcium; Calcium Radioisotopes; Carbachol; Cells, Cultured; Cyclic AMP; Cyclic GMP; Glutamates; Glutamic Acid; Glycine; Hexamethonium; Hexamethonium Compounds; Humans; Neoplasms, Experimental; Nicotine; Norepinephrine; Oxotremorine; Prostaglandins E; Time Factors | 1981 |
Effects of acetylcholine on sodium-dependent high-affinity glutamate transport in rat striatal homogenates.
Topics: Acetylcholine; Animals; Atropine; Biological Transport; Carbachol; Corpus Striatum; Glutamates; Glutamic Acid; Kinetics; Male; Nicotine; Oxotremorine; Rats; Rats, Inbred Strains; Sodium | 1983 |
Regional release of [3H]dopamine from rat brain in vitro: effects of opioids on release induced by potassium, nicotine, and L-glutamic acid.
Topics: Animals; Brain; Dopamine; Endorphins; Enkephalins; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Morphine; Naloxone; Narcotics; Nicotine; Potassium; Rats; Rats, Inbred Strains; Tetrodotoxin; Tritium | 1983 |
Effect of cholinomimetics on the release and uptake of L-[3H] glutamic acid in rat neostriatum.
Topics: Animals; Carbachol; Cerebral Cortex; Cholinergic Fibers; Corpus Striatum; Glutamates; Glutamic Acid; Male; Neural Pathways; Nicotine; Rats; Rats, Inbred Strains; Synaptic Transmission | 1984 |
Nicotine-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Glutamates; Glutamic Acid; Nerve Degeneration; Neurons; Nicotine; Parasympathetic Nervous System; Parasympathomimetics; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate | 1994 |
Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors.
Topics: Animals; Base Sequence; Binding Sites; Brain; Bungarotoxins; Calcium; Chick Embryo; Culture Techniques; Ganglia, Sympathetic; Glutamic Acid; Molecular Sequence Data; Nicotine; Nicotinic Agonists; Presynaptic Terminals; Receptors, Nicotinic; Synapses; Synaptic Transmission; Thalamic Nuclei | 1995 |
Metabolic substrate dependence of carotid chemosensory responses to stop-flow evoked hypoxia and to nicotine.
Topics: Animals; Carotid Body; Cats; Glucose; Glutamates; Glutamic Acid; Hypoxia; In Vitro Techniques; Nicotine; Perfusion | 1993 |
Inhibition by ethanol of the cardiovascular effects of glutamate in the nucleus of the solitary tract.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Heart Rate; Male; Microinjections; Nicotine; Rats; Rats, Sprague-Dawley; Solitary Nucleus | 1994 |
Activation of brain acetylcholine receptors by neuromuscular blocking drugs. A possible mechanism of neurotoxicity.
Topics: Acetylcholine; Anesthesia, General; Animals; Atracurium; Brain; Calcium; Convulsants; Dose-Response Relationship, Drug; Enflurane; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Isoquinolines; Kainic Acid; Male; N-Methylaspartate; Neuromuscular Nondepolarizing Agents; Neurotoxins; Nicotine; Pancuronium; Phenytoin; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Time Factors; Tubocurarine; Vecuronium Bromide | 1994 |
Nicotine induced c-fos expression in the striatum is mediated mostly by dopamine D1 receptor and is dependent on NMDA stimulation.
Topics: Animals; Benzamides; Benzazepines; Clozapine; Corpus Striatum; Dizocilpine Maleate; Gene Expression Regulation; Genes, fos; Glutamates; Glutamic Acid; Male; Mecamylamine; Nicotine; Nucleus Accumbens; Piperazines; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Reward | 1994 |
Nicotine-induced protection against glutamate cytotoxicity. Nicotinic cholinergic receptor-mediated inhibition of nitric oxide formation.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Glutamic Acid; Neurons; Neuroprotective Agents; Neurotoxins; Nicotine; Nitric Oxide; Rats; Receptors, Nicotinic | 1996 |
Effects of nicotine on dopaminergic nigrostriatal axons requires stimulation of presynaptic glutamatergic receptors.
Topics: Animals; Axons; Corpus Striatum; Dose-Response Relationship, Drug; Glutamic Acid; Male; Nicotine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley | 1996 |
Sensitivity of rat frontal cortical neurones to nicotine is increased by chronic administration of nicotine and by lesions of the nucleus basalis magnocellularis: comparison with numbers of [3H]nicotine binding sites.
Topics: Animals; Binding Sites; Frontal Lobe; Glutamic Acid; Male; Neurons; Nicotine; Rats; Rats, Sprague-Dawley; Substantia Innominata; Time Factors; Tritium | 1995 |
Hippocampal synaptic transmission enhanced by low concentrations of nicotine.
Topics: Action Potentials; Animals; Calcium; Culture Techniques; Glutamic Acid; Hippocampus; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Synaptic Membranes; Synaptic Transmission | 1996 |
Nicotinic actions on neurones of the central autonomic area in rat spinal cord slices.
Topics: Acetylcholine; Alkaloids; Animals; Azocines; Cholinergic Agonists; Dimethylphenylpiperazinium Iodide; Evoked Potentials; Glutamic Acid; Isoquinolines; Mecamylamine; Neurons; Nicotine; Patch-Clamp Techniques; Quinolizines; Rats; Rats, Wistar; Receptors, Cholinergic; Spinal Cord; Synaptic Transmission; Tetrodotoxin | 1996 |
Regulation of acetylcholine release by presynaptic nicotinic receptors at developing neuromuscular synapses.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Cells, Cultured; Electric Stimulation; Glutamic Acid; Membrane Potentials; Motor Neurons; Nicotine; Potassium; Presynaptic Terminals; Receptors, Nicotinic; Xenopus laevis | 1997 |
Glutamatergic enteric neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antibodies; Benzothiadiazines; Calcium; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guinea Pigs; Hexamethonium; Ileum; Immunohistochemistry; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Male; Microscopy, Immunoelectron; Muscle, Smooth; Myenteric Plexus; Neurons; Nicotine; Organelles; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Synaptic Vesicles; Tetrodotoxin | 1997 |
Nicotine protects cultured cortical neurons against glutamate-induced cytotoxicity via alpha7-neuronal receptors and neuronal CNS receptors.
Topics: Aconitine; Animals; Bungarotoxins; Cell Survival; Cells, Cultured; Cerebral Cortex; Cysteine; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; Glutamic Acid; Ionomycin; Ionophores; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Antagonists; Rats; Receptors, Nicotinic; S-Nitrosothiols; Toxins, Biological | 1997 |
Effect of glutamate receptor agonists on catecholamine secretion in bovine chromaffin cells.
Topics: Adrenal Medulla; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Cycloleucine; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Nicotine; Receptors, Glutamate | 1998 |
Acetylcholine triggers L-glutamate exocytosis via nicotinic receptors and inhibits melatonin synthesis in rat pinealocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Arylamine N-Acetyltransferase; Atropine; Bungarotoxins; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Carbachol; Cells, Cultured; Diltiazem; Exocytosis; Glutamic Acid; Melatonin; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nifedipine; Nitrendipine; Oxotremorine; Parasympathetic Nervous System; Pineal Gland; Rats; Rats, Wistar; Receptors, Nicotinic; Scopolamine; Synaptic Vesicles; Tubocurarine | 1998 |
Nicotine excites cardiac vagal neurons via three sites of action.
Topics: Acetylcholine; Animals; Ganglionic Stimulants; Glutamic Acid; Heart; Neurons; Nicotine; Patch-Clamp Techniques; Rats; Receptors, Nicotinic; Synapses; Synaptic Transmission; Vagus Nerve | 1998 |
Nicotinic stimulation produces multiple forms of increased glutamatergic synaptic transmission.
Topics: Animals; Cells, Cultured; Electrophysiology; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Learning; Memory; Neurons; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Synaptic Transmission | 1998 |
Nicotine prevents glutamate-induced proteolysis of the microtubule-associated protein MAP-2 and glutamate neurotoxicity in primary cultures of cerebellar neurons.
Topics: Animals; Animals, Newborn; Calcium; Cell Survival; Cells, Cultured; Cerebellum; Excitatory Amino Acid Antagonists; Glutamic Acid; Hexamethonium; Kinetics; Mecamylamine; Microtubule-Associated Proteins; Neurons; Neurotoxins; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Tubulin | 1998 |
Nicotine administration stimulates the in vivo N-methyl-D-aspartate receptor/nitric oxide/cyclic GMP pathway in rat hippocampus through glutamate release.
Topics: Amino Acids; Animals; Cyclic GMP; Ganglionic Stimulants; Glutamic Acid; Guanylate Cyclase; Hippocampus; Injections, Intraperitoneal; Male; N-Methylaspartate; Nicotine; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1998 |
Nicotinic receptors in the rat prefrontal cortex: increase in glutamate release and facilitation of mediodorsal thalamo-cortical transmission.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Animals; Autoradiography; Cerebral Cortex; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Insecticides; Locomotion; Male; Mecamylamine; Microdialysis; Neural Pathways; Neurons, Afferent; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Reaction Time; Receptors, Nicotinic; Synaptic Transmission; Thalamus; Tritium | 1999 |
Hippocampal neurotrophin and trk receptor mRNA levels are altered by local administration of nicotine, carbachol and pilocarpine.
Topics: Acetylcholine; Animals; Behavior, Animal; Brain Chemistry; Brain-Derived Neurotrophic Factor; Carbachol; Cell Death; Cholinergic Agonists; Cholinergic Fibers; Epilepsy; Gene Expression; Glutamic Acid; Hippocampus; In Situ Hybridization; Male; Muscarinic Agonists; Nerve Growth Factors; Neuroprotective Agents; Neurotrophin 3; Nicotine; Nicotinic Agonists; Pilocarpine; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptor, Ciliary Neurotrophic Factor; Receptor, Nerve Growth Factor; Receptor, trkA; Receptor, trkC; Receptors, Nerve Growth Factor; RNA, Messenger; Septal Nuclei; Synaptic Transmission | 1999 |
Calcium signals in cell lines derived from the cerebral cortex of normal and trisomy 16 mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Signaling; Cell Line, Transformed; Cerebral Cortex; Chromosomes, Human, Pair 16; Fetus; Glutamic Acid; Humans; Intracellular Membranes; Kainic Acid; Mice; Mice, Inbred C57BL; Neurons; Nicotine; Osmolar Concentration; Receptors, Glutamate; Reference Values; Trisomy | 1999 |
Nicotinic modulation of glutamate and GABA synaptic transmission of hippocampal neurons.
Topics: Acetylcholine; Animals; Bungarotoxins; Cell Line; Electrophysiology; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Neurons; Nicotiana; Nicotine; Plants, Toxic; Rats; Receptors, Nicotinic; Synaptic Transmission | 1999 |
Pharmacological characterization of nicotine-induced seizures in mice.
Topics: Animals; Anticonvulsants; Brain Chemistry; Calcium Signaling; Dihydropyridines; Glutamic Acid; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Seizures | 1999 |
Nicotine stimulation of extracellular glutamate levels in the nucleus accumbens: neuropharmacological characterization.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Denervation; Dicarboxylic Acids; Dopamine; Extracellular Space; Glutamic Acid; Haloperidol; Kainic Acid; Kinetics; Male; Mecamylamine; Microdialysis; Neurotransmitter Uptake Inhibitors; Nicotine; Nucleus Accumbens; Oxidopamine; Pyrrolidines; Rats; Rats, Sprague-Dawley | 2000 |
Muscarinic receptors depress GABAergic synaptic transmission in rat midbrain dopamine neurons.
Topics: Animals; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Muscarine; Neural Inhibition; Neurons; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, GABA; Receptors, Muscarinic; Receptors, Nicotinic; Substantia Nigra; Synaptic Transmission; Ventral Tegmental Area | 2000 |
Bimodal effects of acetylcholine on synchronized calcium oscillation in rat cultured cortical neurons.
Topics: Acetylcholine; Animals; Calcium; Cell Communication; Cells, Cultured; Cerebral Cortex; Choline O-Acetyltransferase; gamma-Aminobutyric Acid; Glutamic Acid; Neurons; Nicotine; Nicotinic Agonists; Periodicity; Rats; Synaptic Transmission | 2000 |
Brainstem nicotinic receptor subtypes that influence intragastric and arterial blood pressures.
Topics: Animals; Blood Pressure; Glutamic Acid; Hexamethonium; Male; Medulla Oblongata; Microinjections; Nicotine; Pressure; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Stomach | 2000 |
Systemic nicotine stimulates dopamine release in nucleus accumbens: re-evaluation of the role of N-methyl-D-aspartate receptors in the ventral tegmental area.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Ventral Tegmental Area | 2000 |
The nicotinic modulation of [(3)H]D-aspartate outflow in primary cultures of rat neocortical neurons: effect of acute and long term nicotine treatment.
Topics: Acetylcholine; Animals; Aspartic Acid; Cells, Cultured; Electric Stimulation; Glutamic Acid; Neocortex; Neurons; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Presynaptic | 2000 |
The alpha7 nicotinic acetylcholine receptor subtype mediates nicotine protection against NMDA excitotoxicity in primary hippocampal cultures through a Ca(2+) dependent mechanism.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Calcium; Calcium Radioisotopes; Cell Survival; Cells, Cultured; Cytoplasm; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; N-Methylaspartate; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic | 2000 |
Putative role of presynaptic alpha7* nicotinic receptors in nicotine stimulated increases of extracellular levels of glutamate and aspartate in the ventral tegmental area.
Topics: Animals; Aspartic Acid; Extracellular Space; Glutamic Acid; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Tegmentum Mesencephali | 2000 |
Subacute nicotine exposure in cultured cerebellar cells increased the release and uptake of glutamate.
Topics: Animals; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Female; Glutamate-Ammonia Ligase; Glutamic Acid; Male; N-Methylaspartate; Nicotine; Rats; Rats, Sprague-Dawley | 2000 |
Cholinergic modulation of excitatory synaptic transmission in the CA3 area of the hippocampus.
Topics: Animals; Calcium; Cholinergic Agonists; Cholinergic Fibers; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Fura-2; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Mossy Fibers, Hippocampal; Muscarine; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synapses; Synaptic Transmission | 2001 |
Nicotinic receptors mediate the release of amino acid neurotransmitters in cultured cortical neurons.
Topics: Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hexamethonium; Membrane Potentials; Neurons; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Receptors, Nicotinic | 2001 |
alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Androstadienes; Animals; Blotting, Western; Bungarotoxins; Calcineurin; Cell Death; Cells, Cultured; Cerebral Cortex; Chromones; Enzyme Inhibitors; Glutamic Acid; Immunoblotting; Models, Biological; Morpholines; Neurons; Nicotine; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-fyn; Rats; Receptors, Nicotinic; Signal Transduction; Wortmannin | 2001 |
Nicotine-induced enhancement of glutamatergic and GABAergic synaptic transmission in the mouse amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Bicuculline; Excitatory Amino Acid Antagonists; Female; Fetus; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Nicotine; Nicotinic Agonists; Olfactory Bulb; Pregnancy; Synaptic Transmission | 2001 |
Long-lasting enhancement of glutamatergic synaptic transmission by acetylcholine contrasts with response adaptation after exposure to low-level nicotine.
Topics: Acetylcholine; Adaptation, Physiological; Animals; Cells, Cultured; Chick Embryo; Coculture Techniques; Dose-Response Relationship, Drug; Glutamic Acid; Habenula; Mesencephalon; Neural Inhibition; Neural Pathways; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Receptors, Muscarinic; Receptors, Nicotinic; Synapses; Synaptic Transmission | 2001 |
Excitation of rat striatal large neurons by dopamine and/or glutamate released from nerve terminals via presynaptic nicotinic receptor (A4beta2 type) stimulation.
Topics: Action Potentials; Animals; Corpus Striatum; Domperidone; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Glutamic Acid; In Vitro Techniques; Neurons; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Perfusion; Presynaptic Terminals; Rats; Receptors, Nicotinic; Receptors, Presynaptic; Stimulation, Chemical | 2001 |
Regulation of GABA release by nicotinic acetylcholine receptors in the neonatal rat hippocampus.
Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Animals, Newborn; Bicuculline; Bridged-Ring Compounds; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Insecticides; Membrane Potentials; Nicotine; Nicotinic Agonists; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Nicotinic; Spiro Compounds | 2001 |
Enantiospecific synthesis of annulated nicotine analogues from D-glutamic acid. 7-Azabicyclo[2.2.1]heptano[2.3-c]pyridines.
Topics: Aza Compounds; Bridged Bicyclo Compounds, Heterocyclic; Drug Design; Glutamic Acid; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Stereoisomerism | 2001 |
Changes in the glutamate release and uptake of cerebellar cells in perinatally nicotine-exposed rat pups.
Topics: Animals; Animals, Newborn; Cerebellum; Dizocilpine Maleate; Female; Glutamic Acid; Male; N-Methylaspartate; Neurons; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2001 |
Cholinergic transmission via central synapses in the locust nervous system.
Topics: Acetylcholine; Animals; Atropine; Bicuculline; Bungarotoxins; Carbachol; Crotonates; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Glutamic Acid; Grasshoppers; Interneurons; Muscimol; Neurons, Afferent; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Picrotoxin; Receptors, Nicotinic; Synapses; Synaptic Transmission; Tubocurarine | 2001 |
Agrin regulates neuronal responses to excitatory neurotransmitters in vitro and in vivo.
Topics: Agrin; Animals; Calcium Channels; Calcium Signaling; Cell Communication; Cells, Cultured; Cerebral Cortex; Electrophysiology; Epilepsy; Excitatory Amino Acid Agonists; Genotype; Glutamic Acid; Heterozygote; Homozygote; In Vitro Techniques; Kainic Acid; Mice; Neurons; Neurotoxins; Nicotine; Nicotinic Agonists; Phenotype; Proto-Oncogene Proteins c-fos; Receptors, Glutamate | 2002 |
Excitatory and inhibitory responses of dopamine neurons in the ventral tegmental area to nicotine.
Topics: Action Potentials; Animals; Butyrates; Dopamine; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neural Inhibition; Neurons; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Glutamate; Synaptic Transmission; Tobacco Use Disorder; Up-Regulation; Ventral Tegmental Area | 2002 |
Nicotine exposure during a postnatal critical period alters NR2A and NR2B mRNA expression in rat auditory forebrain.
Topics: Aging; Animals; Animals, Newborn; Auditory Cortex; Environmental Exposure; Female; Gene Expression Regulation, Developmental; Geniculate Bodies; Glutamic Acid; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Synaptic Transmission; Tobacco Use Disorder | 2002 |
Ketamine inhibits presynaptic and postsynaptic nicotinic excitation of identified cardiac parasympathetic neurons in nucleus ambiguus.
Topics: Anesthetics, Dissociative; Animals; Bungarotoxins; Dose-Response Relationship, Drug; Electrophysiology; Female; Glutamic Acid; Heart; Heart Rate; In Vitro Techniques; Ion Channel Gating; Ketamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Parasympathetic Nervous System; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Receptors, Presynaptic | 2002 |
Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas.
Topics: Acetylcholinesterase; Action Potentials; Adolescent; Animals; Atropine; Cholinergic Antagonists; Cholinesterase Inhibitors; Dopamine; Electrophysiology; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Ganglionic Stimulants; Glutamic Acid; Humans; In Vitro Techniques; Insecticides; Mice; Muscarinic Antagonists; Neurons; Nicotine; Organothiophosphorus Compounds; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reward; Smoking; Synaptic Transmission; Ventral Tegmental Area | 2002 |
The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system.
Topics: Action Potentials; Allosteric Regulation; Animals; Antibodies, Monoclonal; Central Nervous System; Cholinesterases; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Postsynaptic Potentials; Galantamine; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; In Vitro Techniques; Neurons; Nicotine; Nootropic Agents; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Receptors, Glutamate; Synaptic Transmission; Time Factors | 2002 |
Nicotine alters striatal glutamate function and decreases the apomorphine-induced contralateral rotations in 6-OHDA-lesioned rats.
Topics: Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Corpus Striatum; Drug Administration Schedule; Drug Antagonism; Extracellular Space; Glutamic Acid; Immunohistochemistry; Male; Microdialysis; Microscopy, Electron; Motor Activity; Nicotine; Nicotinic Agonists; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Synapses | 2002 |
Activation of ATP receptor increases the cytosolic Ca(2+) concentration in ventral tegmental area neurons of rat brain.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cytosol; Dopamine; Glutamic Acid; Neurons; Nicotine; Organ Culture Techniques; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X; Sodium; Suramin; Ventral Tegmental Area | 2002 |
Detrimental effects of nicotine and endotoxin in the newborn piglet brain during severe hypoxemia.
Topics: Animals; Animals, Newborn; Blood Pressure; Brain Diseases; Corpus Striatum; Endotoxins; Escherichia coli; Glutamic Acid; Glycerol; Hydrogen-Ion Concentration; Hypoxia; Lactic Acid; Microdialysis; Nicotine; Oxygen; Pyruvic Acid; Swine; Tumor Necrosis Factor-alpha | 2002 |
Cholinergic modulation of nucleus accumbens medium spiny neurons.
Topics: Acetylcholine; Action Potentials; Animals; Cholinergic Agonists; Dopamine Antagonists; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Interneurons; Male; Neural Inhibition; Neural Pathways; Nicotine; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Synaptic Transmission | 2002 |
Nicotinic regulation of CREB activation in hippocampal neurons by glutamatergic and nonglutamatergic pathways.
Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Gene Expression Regulation, Developmental; Glutamic Acid; Hippocampus; Neural Pathways; Neuronal Plasticity; Neurons; Nicotine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Synapses; Synaptic Transmission | 2002 |
Melatonin nocturnal surge modulates nicotinic receptors and nicotine-induced [3H]glutamate release in rat cerebellum slices.
Topics: Adrenergic beta-Antagonists; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Choline; Circadian Rhythm; Darkness; Glutamic Acid; In Vitro Techniques; Light; Male; Melatonin; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Propranolol; Pyridines; Rats; Rats, Wistar; Receptors, Nicotinic | 2003 |
Modulation of presynaptic store calcium induces release of glutamate and postsynaptic firing.
Topics: Action Potentials; Animals; Calcium; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Neurons; Nicotine; Presynaptic Terminals; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Presynaptic | 2003 |
Opposite modulation of glutamate uptake by nicotine in cultured astrocytes with/without cAMP treatment.
Topics: Animals; Astrocytes; Bucladesine; Cell Survival; Cells, Cultured; Cerebellum; Female; Ganglionic Stimulants; Glutamate-Ammonia Ligase; Glutamic Acid; Male; Neuroglia; Nicotine; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase | 2003 |
Glutamate as a precursor for the pyrrolidine ring of nicotine.
Topics: Glutamates; Glutamic Acid; Humans; Nicotine; Prostheses and Implants; Pyrrolidines | 1958 |
Neuroprotection by nicotine in mouse primary cortical cultures involves activation of calcineurin and L-type calcium channel inactivation.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Calcineurin; Calcineurin Inhibitors; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Cerebral Cortex; Glutamic Acid; Mice; Mice, Knockout; Neurons; Neuroprotective Agents; Neurotoxins; Nicotine; Nifedipine; Receptors, Nicotinic; Tacrolimus | 2003 |
Characterization of chronic nicotine exposure on the survival of the spastic Han-Wistar rat.
Topics: Animals; Cerebellum; Ganglionic Stimulants; Glutamic Acid; Hippocampus; Immunohistochemistry; Longevity; Muscle Spasticity; Nicotine; Rats; Rats, Wistar; Receptors, Nicotinic; Survival Analysis; Up-Regulation | 2003 |
Release of [(3)H]-L-glutamate by stimulation of nicotinic acetylcholine receptors in rat cerebellar slices.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cerebellum; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Male; Nicotine; Nicotinic Antagonists; Potassium Chloride; Presynaptic Terminals; Rats; Receptors, Glutamate; Receptors, Nicotinic; Sodium Channels; Stimulation, Chemical; Synaptic Membranes; Synaptic Transmission; Tritium | 2004 |
A two-dimensional imaging biosensor to monitor enhanced brain glutamate release stimulated by nicotine.
Topics: Animals; Animals, Newborn; Biosensing Techniques; Brain; Calcium Chloride; Diagnostic Imaging; Dose-Response Relationship, Drug; Glutamate Dehydrogenase; Glutamic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mice; Monitoring, Physiologic; NAD; Nicotine; Nicotinic Agonists; Potassium Chloride | 2004 |
Acetylcholine protection of adult pig retinal ganglion cells from glutamate-induced excitotoxicity.
Topics: Acetylcholine; Animals; Bungarotoxins; Cell Separation; Cell Survival; Cells, Cultured; Choline; Cytoprotection; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluoresceins; Glutamic Acid; Neuroprotective Agents; Nicotine; Receptors, Nicotinic; Retinal Ganglion Cells; Swine | 2004 |
Prenatal nicotine exposure alters the types of nicotinic receptors that facilitate excitatory inputs to cardiac vagal neurons.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Cholinesterase Inhibitors; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Heart; Neostigmine; Neurons; Nicotine; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, Nicotinic; Synaptic Transmission; Vagus Nerve | 2004 |
The 5-HT receptor antagonist M100,907 prevents extracellular glutamate rising in response to NMDA receptor blockade in the mPFC.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Extracellular Space; Fluorobenzenes; Glutamic Acid; Male; Microdialysis; Nicotine; Piperazines; Piperidines; Potassium Chloride; Prefrontal Cortex; Rats; Receptor, Serotonin, 5-HT2A; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Tetrodotoxin | 2004 |
Prolonged nicotine administration results in biphasic, brain-specific changes in kynurenate levels in the rat.
Topics: Acetylcholine; Animals; Brain; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Administration Schedule; Extracellular Fluid; Glutamic Acid; Hippocampus; Kynurenic Acid; Kynurenine; Male; Nicotine; Rats; Rats, Sprague-Dawley; Smoking; Tobacco Use Disorder; Up-Regulation | 2005 |
The linoleic acid derivative FR236924 facilitates hippocampal synaptic transmission by enhancing activity of presynaptic alpha7 acetylcholine receptors on the glutamatergic terminals.
Topics: Alkanes; Animals; Bicuculline; Bungarotoxins; Chromatography, High Pressure Liquid; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Indoles; Linoleic Acid; Lysine; Male; Maleimides; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Presynaptic Terminals; Protein Kinase C; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Nicotinic; Receptors, Presynaptic; Synaptic Transmission; Valine | 2005 |
Stimulation of nicotinic acetylcholine receptors protects motor neurons.
Topics: Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Cell Death; Cell Survival; Cells, Cultured; Cholinesterase Inhibitors; Dihydro-beta-Erythroidine; Fetus; Galantamine; Glutamic Acid; Immunohistochemistry; Motor Neurons; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Receptors, Nicotinic; Spinal Cord | 2005 |
Nicotine normalizes increased prefrontal cortical dopamine D1 receptor binding and decreased working memory performance produced by repeated pretreatment with MK-801: a PET study in conscious monkeys.
Topics: Animals; Benzazepines; Benzofurans; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Macaca mulatta; Magnetic Resonance Imaging; Male; Memory Disorders; Memory, Short-Term; Microdialysis; Nicotine; Nicotinic Agonists; Positron-Emission Tomography; Prefrontal Cortex; Pyrrolidines; Receptors, Dopamine D1; Salicylamides | 2005 |
Indirect modulation by alpha7 nicotinic acetylcholine receptors of noradrenaline release in rat hippocampal slices: interaction with glutamate and GABA systems and effect of nicotine withdrawal.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bacterial Toxins; Biological Transport; Conotoxins; Cyanobacteria Toxins; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Marine Toxins; Microcystins; Neurons; Nicotine; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Nicotinic; Substance Withdrawal Syndrome; Tetrodotoxin; Tropanes | 2006 |
Nicotinic and muscarinic reduction of unitary excitatory postsynaptic potentials in sensory cortex; dual intracellular recording in vitro.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Cholinergic Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Magnesium; Mecamylamine; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyramidal Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex | 2006 |
P2X(7) receptors exert a permissive role on the activation of release-enhancing presynaptic alpha7 nicotinic receptors co-existing on rat neocortex glutamatergic terminals.
Topics: Adenosine Triphosphate; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Aspartic Acid; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Choline; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Enzyme Activation; Glutamic Acid; In Vitro Techniques; Magnesium; Male; Neocortex; Nicotine; Nicotinic Agonists; Presynaptic Terminals; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Time Factors; Tritium | 2006 |
Facilitation of glutamate release by nicotine involves the activation of a Ca2+/calmodulin signaling pathway in rat prefrontal cortex nerve terminals.
Topics: 4-Aminopyridine; Animals; Calcium Channels; Calcium Signaling; Calmodulin; Glutamic Acid; Male; Membrane Potentials; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Potassium Channel Blockers; Prefrontal Cortex; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Signal Transduction; Synaptosomes | 2006 |
The nicotinic agonist RJR-2403 compensates the impairment of eyeblink conditioning produced by the noncompetitive NMDA-receptor antagonist MK-801.
Topics: Animals; Blinking; Conditioning, Eyelid; Dizocilpine Maleate; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists | 2006 |
Iptakalim inhibits nicotine-induced enhancement of extracellular dopamine and glutamate levels in the nucleus accumbens of rats.
Topics: Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Extracellular Space; Glutamic Acid; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Propylamines; Rats | 2006 |
Specific changes in levels of autoantibodies to glutamate and opiate receptors induced by morphine administration in rats.
Topics: Animals; Astrocytes; Autoantibodies; Biomarkers; Dextroamphetamine; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Male; Morphine; Nerve Growth Factors; Nicotine; Protein Subunits; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Receptors, Opioid, mu; S100 Calcium Binding Protein beta Subunit; S100 Proteins | 2006 |
Prenatal nicotine exposure alters the nicotinic receptor subtypes that modulate excitation of parasympathetic cardiac neurons in the nucleus ambiguus from primarily alpha3beta2 and/or alpha6betaX to alpha3beta4.
Topics: Alkaloids; Animals; Azocines; Basal Ganglia; Conotoxins; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Heart; Neurons; Nicotine; Nicotinic Antagonists; Parasympathetic Nervous System; Pregnancy; Prenatal Exposure Delayed Effects; Quinolizines; Rats; Receptors, Nicotinic; Synaptic Transmission; Vagus Nerve | 2006 |
Iptakalim inhibits nicotinic acetylcholine receptor-mediated currents in dopamine neurons acutely dissociated from rat substantia nigra pars compacta.
Topics: Acetylcholine; Action Potentials; Animals; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Propylamines; Rats; Rats, Wistar; Receptors, Nicotinic; Substantia Nigra | 2006 |
Behavioral interaction between nicotine and ethanol: possible modulation by mouse cerebellar glutamate.
Topics: Animals; Behavior, Animal; Cerebellum; Ethanol; Glutamic Acid; Male; Mice; Motor Activity; Nicotine | 2006 |
Nicotine-induced changes of glutamate and arginine in naive and chronically alcoholized rats: an in vivo microdialysis study.
Topics: Alcohol-Induced Disorders, Nervous System; Animals; Arginine; Brain Chemistry; Central Nervous System Depressants; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Ethanol; Extracellular Fluid; Glutamic Acid; Male; Microdialysis; Nicotine; Nicotinic Agonists; Nitric Oxide; Nucleus Accumbens; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2006 |
Nicotine stimulation on extracellular glutamate levels in the nucleus accumbens of ethanol-withdrawn rats in vivo.
Topics: Alcoholic Intoxication; Animals; Ethanol; Extracellular Fluid; Glutamic Acid; Male; Nicotine; Nucleus Accumbens; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 2006 |
Knockdown of amyloid precursor protein normalizes cholinergic function in a cell line derived from the cerebral cortex of a trisomy 16 mouse: An animal model of down syndrome.
Topics: Acetylcholine; Algorithms; Amyloid beta-Protein Precursor; Animals; Blotting, Western; Cell Line; Cerebral Cortex; Cholera Toxin; Choline; Down Syndrome; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Mice; Nicotine; Parasympathetic Nervous System; Potassium Chloride; RNA, Antisense; RNA, Messenger; Superoxide Dismutase; Superoxide Dismutase-1; Trisomy | 2006 |
Failure of nicotine-dependent enhancement of synaptic efficacy at Schaffer-collateral CA1 synapses of AD11 anti-nerve growth factor transgenic mice.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Bungarotoxins; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Immunohistochemistry; In Vitro Techniques; Mice; Mice, Transgenic; Nerve Growth Factor; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Peptide Fragments; Probability; Receptors, Nicotinic; Synapses | 2006 |
Persistent rhythmic oscillations induced by nicotine on neonatal rat hypoglossal motoneurons in vitro.
Topics: Action Potentials; Animals; Animals, Newborn; Biological Clocks; Brain Stem; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoglossal Nerve; Motor Neurons; Nicotine; Nicotinic Agonists; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Theta Rhythm; Tongue | 2006 |
Chronic nicotine-induced switch in Src-family kinase signaling for long-term potentiation induction in hippocampal CA1 pyramidal cells.
Topics: Animals; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 2; Glutamic Acid; Hippocampus; Long-Term Potentiation; Memory; Nicotine; Nicotinic Agonists; Phosphorylation; Protein Kinase C; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction; src-Family Kinases; Synaptic Transmission; Tobacco Use Disorder | 2006 |
Presynaptic calcium stores contribute to nicotine-elicited potentiation of evoked synaptic transmission at CA3-CA1 connections in the neonatal rat hippocampus.
Topics: Animals; Animals, Newborn; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Indoles; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Ryanodine; Synaptic Transmission; Thapsigargin | 2007 |
Chronic nicotine administration. Analysis of the development of hypertension and glutamatergic neurotransmission.
Topics: Analysis of Variance; Animals; Blood Pressure; Brain; Chromatography, High Pressure Liquid; Competitive Bidding; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Agonists; Gene Expression Regulation; Glutamic Acid; Hypertension; In Situ Hybridization; Male; Nicotine; Nicotinic Agonists; Protein Binding; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2007 |
Nicotine-induced phosphorylation of ERK in mouse primary cortical neurons: evidence for involvement of glutamatergic signaling and CaMKII.
Topics: Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Cerebral Cortex; Culture Media; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Female; Glutamic Acid; Indicators and Reagents; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Nicotine; Nicotinic Agonists; Phosphorylation; Pregnancy; Receptors, Glutamate; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Synaptic Transmission | 2007 |
Smoking and alcoholism target genes associated with plasticity and glutamate transmission in the human ventral tegmental area.
Topics: Alcoholism; Base Sequence; Blotting, Western; Case-Control Studies; DNA Probes; Ethanol; Female; Gene Expression Profiling; Glutamic Acid; Humans; Male; Neuronal Plasticity; Nicotine; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; RNA, Messenger; Smoking; Synaptic Transmission; Ventral Tegmental Area; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2 | 2008 |
Differential modulation by nicotine of substantia nigra versus ventral tegmental area dopamine neurons.
Topics: Acetylcholine; Animals; Choline; Data Interpretation, Statistical; Dopamine; Electrophysiology; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Male; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Substantia Nigra; Synapses; Ventral Tegmental Area | 2007 |
Voluntary oral nicotine intake in mice down-regulates GluR2 but does not modulate depression-like behaviors.
Topics: Administration, Oral; Animals; Anxiety Disorders; Behavior, Animal; Brain; Cyclic AMP Response Element-Binding Protein; Depressive Disorder; Down-Regulation; Glutamic Acid; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Motor Activity; Neural Pathways; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Receptors, AMPA; Reward; Synaptic Transmission; Tobacco Use Disorder; Ventral Tegmental Area; Volition | 2008 |
Facilitation of cortico-amygdala synapses by nicotine: activity-dependent modulation of glutamatergic transmission.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amygdala; Animals; Animals, Genetically Modified; Cerebral Cortex; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Pyramidal Cells; Receptors, Nicotinic; Synapses; Synaptic Transmission | 2008 |
Glutamatergic contributions to nicotinic acetylcholine receptor agonist-evoked cholinergic transients in the prefrontal cortex.
Topics: Acetylcholine; Analysis of Variance; Animals; Choline; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electrochemistry; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Male; Mecamylamine; Neostigmine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex; Pyridines; Pyrrolidines; Quinoxalines; Rats; Sodium Channel Blockers; Tetrodotoxin; Valine | 2008 |
Riluzole blocks persistent Na+ and Ca2+ currents and modulates release of glutamate via presynaptic NMDA receptors on neonatal rat hypoglossal motoneurons in vitro.
Topics: Action Potentials; Animals; Animals, Newborn; Calcium Channels; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoglossal Nerve; Ion Channels; Motor Neurons; Neuroprotective Agents; Nicotine; Organ Culture Techniques; Patch-Clamp Techniques; Protein Kinase C; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Riluzole; Sodium Channel Blockers; Sodium Channels; Synaptic Transmission; Theta Rhythm | 2008 |
Neuroadaptive changes in the mesocortical glutamatergic system during chronic nicotine self-administration and after extinction in rats.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Electrochemistry; Excitatory Amino Acid Agents; Extinction, Psychological; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; N-Methylaspartate; Nicotine; Nicotinic Agonists; Potassium Chloride; Prefrontal Cortex; Rats; Rats, Inbred Lew; Self Administration; Ventral Tegmental Area | 2008 |
Presynaptic type III neuregulin 1 is required for sustained enhancement of hippocampal transmission by nicotine and for axonal targeting of alpha7 nicotinic acetylcholine receptors.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Cycloheximide; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; Glutamic Acid; Hippocampus; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Neuregulins; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Organ Culture Techniques; Patch-Clamp Techniques; Presynaptic Terminals; Protein Synthesis Inhibitors; Receptors, Nicotinic; Synaptic Transmission; Time Factors; Vesicular Glutamate Transport Protein 1 | 2008 |
Effects of nicotine infusion on striatal glutamate and cortical non-protein-bound iron in hypoxic newborn piglets.
Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Corpus Striatum; Disease Models, Animal; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Iron; Neuroprotective Agents; Nicotine; Random Allocation; Swine | 2008 |
Rats harboring S284L Chrna4 mutation show attenuation of synaptic and extrasynaptic GABAergic transmission and exhibit the nocturnal frontal lobe epilepsy phenotype.
Topics: Age Factors; Analysis of Variance; Animals; Behavior, Animal; Cerebral Cortex; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Frontal Lobe; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hot Temperature; In Vitro Techniques; Leucine; Microscopy, Immunoelectron; Motor Activity; Motor Skills; Mutation; Neurotransmitter Agents; Nicotine; Pain Measurement; Pentylenetetrazole; Phenotype; Rats; Rats, Transgenic; Receptors, Nicotinic; Serine; Synaptic Transmission | 2008 |
Four excitatory postsynaptic ionotropic receptors coactivated at the motoneuron-Renshaw cell synapse.
Topics: Animals; Animals, Newborn; Biophysics; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Interneurons; Mice; Mice, Inbred C57BL; Motor Neurons; Neural Inhibition; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Receptors, Glutamate; Receptors, Nicotinic; Spinal Cord; Synapses | 2008 |
Extreme tolerance to ammonia fumes in African naked mole-rats: animals that naturally lack neuropeptides from trigeminal chemosensory nerve fibers.
Topics: Ammonia; Animals; Capsaicin; Central Nervous System; Discrimination Learning; Exploratory Behavior; Glutamic Acid; Irritants; Mice; Mice, Inbred C57BL; Mole Rats; Nerve Fibers, Unmyelinated; Nerve Tissue Proteins; Neuropeptides; Nicotine; Nociceptors; Odorants; Olivary Nucleus; Proto-Oncogene Proteins c-fos; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Single-Blind Method; Solitary Nucleus; Species Specificity; Trigeminal Nucleus, Spinal | 2009 |
Nicotine-induced and depolarisation-induced glutamate release from hippocampus mossy fibre synaptosomes: two distinct mechanisms.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cell Polarity; Glutamic Acid; Hippocampus; Male; Membrane Potentials; Mossy Fibers, Hippocampal; Nicotine; Rats; Rats, Wistar; Receptors, Nicotinic; Synaptosomes | 2009 |
Nicotine modulates GABAergic transmission to dopaminergic neurons in substantia nigra pars compacta.
Topics: Acetylcholine; Animals; Calcium; Dopamine; Glutamic Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neurons; Nicotine; Nicotinic Agonists; Rats; Receptors, GABA-A; Receptors, Nicotinic; Receptors, Presynaptic; Substantia Nigra | 2009 |
Nicotinic activation of laterodorsal tegmental neurons: implications for addiction to nicotine.
Topics: Animals; Calcium; Dendrites; Female; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Intracellular Space; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Presynaptic Terminals; Receptors, Nicotinic; Synaptic Transmission; Tegmentum Mesencephali; Tobacco Use Disorder | 2009 |
Second-by-second analysis of alpha 7 nicotine receptor regulation of glutamate release in the prefrontal cortex of awake rats.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Calibration; Catheterization; Choline; Electrodes, Implanted; Glutamic Acid; Kynurenine; Male; Microelectrodes; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Nicotinic; Time Factors | 2009 |
Nicotine stimulation of the medulla increases blood flow of the common carotid artery in cats.
Topics: Animals; Carotid Artery, Common; Cats; Choline; Dose-Response Relationship, Drug; Female; Glutamic Acid; Hemodynamics; Male; Medulla Oblongata; Microinjections; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Protein Isoforms; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Regional Blood Flow; Stimulation, Chemical | 2010 |
Chronic nicotine selectively enhances alpha4beta2* nicotinic acetylcholine receptors in the nigrostriatal dopamine pathway.
Topics: Animals; Dopamine; Drug Administration Schedule; Evoked Potentials; GABA Agents; Glutamic Acid; Mice; Mice, Inbred C57BL; Neurons; Nicotine; Patch-Clamp Techniques; Receptors, Nicotinic; Substantia Nigra; Up-Regulation | 2009 |
Activation of presynaptic alpha7 nicotinic receptors evokes an excitatory response in hippocampal CA3 neurones in anaesthetized rats: an in vivo iontophoretic study.
Topics: 2-Amino-5-phosphonovalerate; Aconitine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; D-Aspartic Acid; Glutamic Acid; Hippocampus; Male; N-Methylaspartate; Neurons; Nicotine; Nicotinic Antagonists; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Presynaptic; Spiro Compounds | 2010 |
Nicotine self-administration differentially modulates glutamate and GABA transmission in hypothalamic paraventricular nucleus to enhance the hypothalamic-pituitary-adrenal response to stress.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Disease Models, Animal; Electric Stimulation; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamo-Hypophyseal System; Male; Neuronal Plasticity; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Self Administration; Stress, Psychological; Synaptic Transmission; Tobacco Use Disorder | 2010 |
Stimulation of lateral hypothalamic glutamate and acetylcholine efflux by nicotine: implications for mechanisms of nicotine-induced activation of orexin neurons.
Topics: Acetylcholine; Animals; Appetite; Arousal; Drug Administration Schedule; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamic Area, Lateral; Intracellular Signaling Peptides and Proteins; Male; Microdialysis; Neural Pathways; Neurons; Neuropeptides; Nicotine; Nicotinic Agonists; Orexins; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tobacco Use Disorder; Up-Regulation | 2010 |
Exposure of nicotine to ventral tegmental area slices induces glutamatergic synaptic plasticity on dopamine neurons.
Topics: Animals; Dopamine; Excitatory Postsynaptic Potentials; Glutamic Acid; Neuronal Plasticity; Neurons; Nicotine; Rats; Rats, Wistar; Synapses; Time Factors; Ventral Tegmental Area | 2011 |
Mechanisms involved in systemic nicotine-induced glutamatergic synaptic plasticity on dopamine neurons in the ventral tegmental area.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Dopamine; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Postsynaptic Potentials; Genotype; Glutamic Acid; Mice; Mice, Knockout; Neuronal Plasticity; Neurons; Nicotine; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; Synapses; Ventral Tegmental Area | 2010 |
Developmental nicotine exposure alters neurotransmission and excitability in hypoglossal motoneurons.
Topics: Animals; Animals, Newborn; Biophysical Phenomena; Female; Glutamic Acid; Hypoglossal Nerve; Male; Models, Animal; Motor Neurons; Nicotine; Patch-Clamp Techniques; Pregnancy; Prenatal Exposure Delayed Effects; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Synaptic Transmission | 2011 |
Mechanisms of facilitation of synaptic glutamate release by nicotinic agonists in the nucleus of the solitary tract.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Caffeine; Calcium Signaling; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Mecamylamine; Microscopy, Fluorescence; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Sodium Channel Blockers; Solitary Nucleus; Synaptic Transmission; Temperature; Tetrodotoxin; Time Factors | 2011 |
Anterior cingulate proton spectroscopy glutamate levels differ as a function of smoking cessation outcome.
Topics: Administration, Cutaneous; Creatine; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Nicotine; Nicotinic Agonists; Recurrence; Smoking; Smoking Cessation; Smoking Prevention; Tobacco Use Disorder; Treatment Outcome | 2011 |
Dual effect of beta-amyloid on α7 and α4β2 nicotinic receptors controlling the release of glutamate, aspartate and GABA in rat hippocampus.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Aspartic Acid; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Immunohistochemistry; Male; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Potassium; Rats; Rats, Wistar; Receptors, Nicotinic; Time Factors; Veratridine | 2012 |
Chronic nicotine exposure selectively activates a carrier-mediated release of endogenous glutamate and aspartate from rat hippocampal synaptosomes.
Topics: Animals; Aspartic Acid; Carrier Proteins; Drug Administration Schedule; Glutamic Acid; Hippocampus; Male; Nicotine; Nicotinic Agonists; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Synaptosomes | 2012 |
Evidence supporting the role of calpain in the α-processing of amyloid-β precursor protein.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Biotinylation; Calpain; Cell Membrane; Genetic Vectors; Glutamic Acid; HEK293 Cells; Humans; Nicotine; Phorbol 12,13-Dibutyrate; Substrate Specificity | 2012 |
Glutamatergic synapse formation is promoted by α7-containing nicotinic acetylcholine receptors.
Topics: Age Factors; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Animals, Newborn; Cells, Cultured; Disks Large Homolog 4 Protein; Electric Stimulation; Embryo, Mammalian; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Gene Expression Regulation, Developmental; Glutamic Acid; Green Fluorescent Proteins; Guanylate Kinases; Hippocampus; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron, Transmission; Neurites; Neurons; Nicotine; Nicotinic Agonists; Organ Culture Techniques; Patch-Clamp Techniques; Pyridazines; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Receptors, AMPA; Receptors, Nicotinic; RNA, Small Interfering; Sodium Channel Blockers; Synapses; Tetrodotoxin; Time Factors; Transduction, Genetic; Vesicular Glutamate Transport Protein 1; Visual Cortex | 2012 |
Induction of dendritic spines by β2-containing nicotinic receptors.
Topics: Animals; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Cerebral Cortex; Dendritic Spines; Glutamic Acid; Hippocampus; Mice; Mice, Knockout; Neurons; Nicotine; Protein Subunits; Receptors, Nicotinic; RNA, Small Interfering; Synapses | 2012 |
Glutamatergic and GABAergic metabolism in mouse brain under chronic nicotine exposure: implications for addiction.
Topics: Acetates; Animals; Behavior, Animal; Brain; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Nicotine; Oxidation-Reduction; Signal Transduction; Substance-Related Disorders | 2012 |
In vivo comparison of harmine efficacy against psychostimulants: preferential inhibition of the cocaine response through a glutamatergic mechanism.
Topics: Amphetamines; Animals; Cocaine; Excitatory Amino Acid Antagonists; Glutamic Acid; Harmine; Inhibition, Psychological; Kainic Acid; Nicotine; Nicotinic Antagonists; Planarians; Psychotropic Drugs | 2012 |
Adolescent rats are resistant to adaptations in excitatory and inhibitory mechanisms that modulate mesolimbic dopamine during nicotine withdrawal.
Topics: Adaptation, Physiological; Age Factors; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Dialysis; Dopamine; Electrochemistry; gamma-Aminobutyric Acid; Glutamic Acid; Limbic System; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Statistics as Topic; Substance Withdrawal Syndrome; Ventral Tegmental Area | 2012 |
Orally active metabotropic glutamate subtype 2 receptor positive allosteric modulators: structure-activity relationships and assessment in a rat model of nicotine dependence.
Topics: Administration, Oral; Allosteric Regulation; Animals; Behavior, Animal; Brain; Glutamic Acid; HEK293 Cells; Humans; Indoles; Microsomes, Liver; Molecular Structure; Nicotine; Rats; Receptors, Metabotropic Glutamate; Structure-Activity Relationship; Tissue Distribution; Tobacco Use Disorder | 2012 |
Presynaptic α4β2 nicotinic acetylcholine receptors increase glutamate release and serotonin neuron excitability in the dorsal raphe nucleus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Aconitine; Animals; Animals, Newborn; Atropine; Bicuculline; Cadmium Chloride; Chelating Agents; Cholinergic Agonists; Dihydro-beta-Erythroidine; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Indoles; Male; Muscarinic Antagonists; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Physostigmine; Presynaptic Terminals; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Nicotinic; Ryanodine; Serotonergic Neurons; Serotonin; Sodium Channel Blockers; Tetrodotoxin | 2012 |
Involvement of NMDA receptors in nicotine-mediated central control of hypotensive effects.
Topics: Animals; Blood Pressure; Bradycardia; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Hypotension; Male; Nicotine; Nicotinic Agonists; Quinoxalines; Rats; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Solitary Nucleus; Valine | 2012 |
Neuroprotection of rat retinal ganglion cells mediated through alpha7 nicotinic acetylcholine receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Apoptosis; Benzamides; Bridged Bicyclo Compounds; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Female; Glutamic Acid; In Situ Nick-End Labeling; Male; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Rats; Rats, Long-Evans; Receptors, Nicotinic; Retina; Retinal Ganglion Cells; Time Factors | 2013 |
Regulation of glutamate release by heteromeric nicotinic receptors in layer V of the secondary motor region (Fr2) in the dorsomedial shoulder of prefrontal cortex in mouse.
Topics: Animals; Cerebral Cortex; Excitatory Postsynaptic Potentials; Gene Expression; Glutamic Acid; Interneurons; Mice; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Post-Synaptic Density; Pyramidal Cells; Receptors, Nicotinic; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2 | 2013 |
Effects of the beta-lactam antibiotic ceftriaxone on nicotine withdrawal and nicotine-induced reinstatement of preference in mice.
Topics: Amino Acid Transport Systems; Animals; Anti-Bacterial Agents; Ceftriaxone; Conditioning, Psychological; Cysteine; Excitatory Amino Acid Transporter 2; Extinction, Psychological; Glutamic Acid; Male; Mice; Mice, Inbred ICR; Nicotine; Reinforcement, Psychology; Reward; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2013 |
Acetylcholinesterase inhibition reveals endogenous nicotinic modulation of glutamate inputs to CA1 stratum radiatum interneurons in hippocampal slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Age Factors; Animals; Animals, Newborn; CA1 Region, Hippocampal; Cholinesterase Inhibitors; Donepezil; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Indans; Interneurons; Lethal Dose 50; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Piperidines; Rats; Soman | 2013 |
Selective potentiation of (α4)3(β2)2 nicotinic acetylcholine receptors augments amplitudes of prefrontal acetylcholine- and nicotine-evoked glutamatergic transients in rats.
Topics: Acetylcholine; Allosteric Regulation; Animals; Glutamic Acid; HEK293 Cells; Humans; Microelectrodes; Nicotine; Nicotinic Agonists; Oxadiazoles; Prefrontal Cortex; Pyridines; Rats; Receptors, Nicotinic | 2013 |
Full-gestational exposure to nicotine and ethanol augments nicotine self-administration by altering ventral tegmental dopaminergic function due to NMDA receptors in adolescent rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blotting, Western; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Dopaminergic Neurons; Electrochemistry; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Microinjections; N-Methylaspartate; Nicotine; Nicotinic Agonists; Polymerase Chain Reaction; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Self Administration; Ventral Tegmental Area | 2014 |
Activation of GABAergic neurons in the interpeduncular nucleus triggers physical nicotine withdrawal symptoms.
Topics: Animals; GABAergic Neurons; Glutamic Acid; Light; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phototherapy; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Rhodopsin; Somatostatin; Substance Withdrawal Syndrome; Synaptic Transmission | 2013 |
Inhibitory effects of beta-amyloid on the nicotinic receptors which stimulate glutamate release in rat hippocampus: the glial contribution.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Aspartic Acid; Azetidines; Bridged Bicyclo Compounds, Heterocyclic; Choline; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Peptide Fragments; Pyridines; Quinuclidines; Rats; Rats, Wistar; Receptors, Nicotinic | 2014 |
Primary cultures of rat cortical microglia treated with nicotine increases in the expression of excitatory amino acid transporter 1 (GLAST) via the activation of the α7 nicotinic acetylcholine receptor.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamic Acid; Inositol 1,4,5-Trisphosphate Receptors; Microglia; Nicotine; Nicotinic Agonists; Rats; RNA, Messenger; Signal Transduction | 2014 |
Nicotine decreases the activity of glutamate transporter type 3.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Excitatory Amino Acid Transporter 3; Female; Glutamic Acid; Membrane Potentials; Nicotine; Nicotinic Agonists; Oocytes; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Rats; Seizures; Time Factors; Xenopus laevis | 2014 |
Differential role of N-methyl-D-aspartate receptor-mediated glutamate transmission in the nucleus accumbens shell and core in nicotine seeking in rats.
Topics: Animals; Drug-Seeking Behavior; Excitatory Amino Acid Antagonists; Glutamic Acid; Isoquinolines; Male; Nicotine; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Self Administration; Synaptic Transmission | 2014 |
A novel mechanism for nicotinic potentiation of glutamatergic synapses.
Topics: Animals; Animals, Newborn; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hippocampus; Male; Mice; Mice, Inbred C57BL; Nicotine; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Synapses | 2014 |
High-energy compounds mobilize intracellular Ca2+ and activate calpain in cultured cells: is calpain an energy-dependent protease?
Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Alzheimer Disease; Calcium; Calpain; Cell Line, Tumor; Chelating Agents; Cysteine Proteinase Inhibitors; Dipeptides; Egtazic Acid; Extracellular Space; Glutamic Acid; Humans; Intracellular Space; Nicotine; Nicotinic Agonists; Phosphocreatine; Phosphoenolpyruvate; Rotenone; Uncoupling Agents | 2014 |
A systemically-available kynurenine aminotransferase II (KAT II) inhibitor restores nicotine-evoked glutamatergic activity in the cortex of rats.
Topics: Animals; Central Nervous System Agents; Enzyme Inhibitors; Glutamic Acid; Kynurenic Acid; Kynurenine; Male; Membrane Potentials; Microdialysis; Microelectrodes; Nicotine; Nicotinic Agonists; Potassium Chloride; Prefrontal Cortex; Pyrazoles; Rats, Sprague-Dawley; Rats, Wistar; Transaminases | 2014 |
Altered neurochemical levels in the rat brain following chronic nicotine treatment.
Topics: Acetylcholine; Animals; Brain; Carnitine; Chromatography, Liquid; Glutamic Acid; Mass Spectrometry; Nicotine; Nicotinic Agonists; Rats; Rats, Long-Evans | 2014 |
Neonatal nicotine exposure increases excitatory synaptic transmission and attenuates nicotine-stimulated GABA release in the adult rat hippocampus.
Topics: Animals; Animals, Newborn; CA1 Region, Hippocampal; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Inhibitory Postsynaptic Potentials; Male; Miniature Postsynaptic Potentials; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Pyramidal Cells; Rats, Sprague-Dawley; Receptors, AMPA; Synaptic Transmission; Tissue Culture Techniques | 2015 |
Prenatal nicotine is associated with reduced AMPA and NMDA receptor-mediated rises in calcium within the laterodorsal tegmentum: a pontine nucleus involved in addiction processes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Female; Glutamic Acid; Humans; Mice; Motivation; N-Methylaspartate; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Substance-Related Disorders; Tegmentum Mesencephali | 2015 |
Nicotinic receptor subtype-selective circuit patterns in the subthalamic nucleus.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cholinergic Agents; Glutamic Acid; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Nerve Net; Nicotine; Receptors, Nicotinic; Subthalamic Nucleus; Synapses | 2015 |
Prenatal Nicotine Exposure Impairs the Proliferation of Neuronal Progenitors, Leading to Fewer Glutamatergic Neurons in the Medial Prefrontal Cortex.
Topics: Animals; Cell Cycle; Cell Movement; Cognition Disorders; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice, Inbred C57BL; Neural Stem Cells; Neurogenesis; Neurons; Nicotine; Nicotinic Agonists; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation | 2016 |
Co-administration of ethanol and nicotine: the enduring alterations in the rewarding properties of nicotine and glutamate activity within the mesocorticolimbic system of female alcohol-preferring (P) rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Drug Combinations; Ethanol; Female; Glutamic Acid; Limbic System; Nicotine; Nucleus Accumbens; Rats; Reward; Self Administration | 2015 |
Stimulation of α7 nicotinic acetylcholine receptor regulates glutamate transporter GLAST via basic fibroblast growth factor production in cultured cortical microglia.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Cholinergic Agents; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Transporter 1; Fibroblast Growth Factor 2; Glutamic Acid; Microglia; Nicotine; Pyrimidines; Rats; Rats, Wistar; Time Factors; Up-Regulation | 2015 |
Nicotinic receptor activation contrasts pathophysiological bursting and neurodegeneration evoked by glutamate uptake block on rat hypoglossal motoneurons.
Topics: Action Potentials; Amyotrophic Lateral Sclerosis; Animals; Aspartic Acid; Brain Stem; Endoplasmic Reticulum Stress; Glucosyltransferases; Glutamic Acid; Hypoglossal Nerve; Motor Neurons; Neurodegenerative Diseases; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Nicotinic | 2016 |
Influence of developmental nicotine exposure on glutamatergic neurotransmission in rhythmically active hypoglossal motoneurons.
Topics: Age Factors; Animals; Animals, Newborn; Drug Interactions; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hypoglossal Nerve; In Vitro Techniques; Male; Medulla Oblongata; Membrane Potentials; Motor Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Synaptic Transmission; Tetrodotoxin | 2017 |
Nicotinic receptor subtypes differentially modulate glutamate release in the dorsal medial striatum.
Topics: Acetylcholine; Animals; Cells, Cultured; Corpus Striatum; Dopamine; Glutamic Acid; Male; Nicotine; Presynaptic Terminals; Rats, Long-Evans; Receptors, Nicotinic | 2016 |
Increased nicotine response in iPSC-derived human neurons carrying the CHRNA5 N398 allele.
Topics: Alleles; Cells, Cultured; Gene Expression Profiling; Genetic Variation; Glutamic Acid; Humans; Induced Pluripotent Stem Cells; Nerve Tissue Proteins; Neurons; Nicotine; Receptors, Nicotinic | 2016 |
Nicotinic receptors modulate the onset of reactive oxygen species production and mitochondrial dysfunction evoked by glutamate uptake block in the rat hypoglossal nucleus.
Topics: Animals; Animals, Newborn; Brain Stem; Glutamic Acid; Hypoglossal Nerve; Mitochondria; Motor Neurons; Nicotine; Rats, Wistar; Reactive Oxygen Species; Receptors, Glutamate; Receptors, Nicotinic | 2017 |
Perinatal nicotine exposure impairs the maturation of glutamatergic inputs in the auditory brainstem.
Topics: Animals; Brain Stem; Down-Regulation; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neurons; Nicotine; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Cholinergic; Synapses | 2017 |
Amino acid modulation of dopamine in the nucleus accumbens mediates sex differences in nicotine withdrawal.
Topics: Amino Acids; Animals; Disease Models, Animal; Dopamine; Female; Glutamic Acid; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Sex Factors; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2018 |
Behavioral changes after nicotine challenge are associated with α7 nicotinic acetylcholine receptor-stimulated glutamate release in the rat dorsal striatum.
Topics: Action Potentials; alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Corpus Striatum; Glutamic Acid; Male; Motor Activity; Nicotine; Nicotinic Agonists; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2017 |
Prenatal nicotine exposure alters postsynaptic AMPA receptors and glutamate neurotransmission within the laterodorsal tegmentum (LDT) of juvenile mice.
Topics: Animals; Calcium; Cations, Divalent; Female; Glutamic Acid; Male; Membrane Potentials; Mice; Nicotine; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Tegmentum Mesencephali; Tissue Culture Techniques | 2018 |
Effects of acute and chronic nicotine on catecholamine neurons of the nucleus of the solitary tract.
Topics: Action Potentials; Animals; Catecholamines; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Male; Mice, Transgenic; Neurons; Nicotine; Receptors, Nicotinic; Solitary Nucleus; Synaptic Transmission | 2019 |
Chronic treatment with N-acetylcysteine decreases extinction responding and reduces cue-induced nicotine-seeking.
Topics: Acetylcysteine; Animals; Cues; Dendritic Spines; Drug-Seeking Behavior; Extinction, Psychological; Glutamic Acid; Male; Neuronal Plasticity; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Self Administration | 2019 |
Acetylcholine receptor agonist effect on seizure activity and GABAergic mechanisms involved in prolonged febrile seizure development in an animal model.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cholinergic Agonists; Disease Models, Animal; Female; GABAergic Neurons; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Hippocampus; Male; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Receptors, Nicotinic; Seizures, Febrile; Synaptic Transmission | 2019 |
Lasting reduction of nicotine-seeking behavior by chronic N-acetylcysteine during experimental cue-exposure therapy.
Topics: Acetylcysteine; Animals; Behavior, Animal; Cues; Drug-Seeking Behavior; Extinction, Psychological; Free Radical Scavengers; Glutamic Acid; Implosive Therapy; Male; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats; Receptors, AMPA; Recurrence; Tobacco Use Disorder | 2020 |
Accumbens neuroimmune signaling and dysregulation of astrocytic glutamate transport underlie conditioned nicotine-seeking behavior.
Topics: Acetylcysteine; Animals; Astrocytes; Conditioning, Psychological; Disease Models, Animal; Drug-Seeking Behavior; Glial Fibrillary Acidic Protein; Glutamic Acid; Male; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Self Administration; Signal Transduction; Tumor Necrosis Factor-alpha | 2020 |
A neurobiological correlate of stress-induced nicotine-seeking behavior among cigarette smokers.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Cigarette Smoking; Double-Blind Method; Drug-Seeking Behavior; Female; Functional Neuroimaging; Glutamic Acid; Humans; Hydrocortisone; Male; Memory, Short-Term; Nicotine; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Random Allocation; Smokers; Stress, Physiological; Tobacco Use Disorder; Yohimbine; Young Adult | 2020 |
Cognitive rigidity and BDNF-mediated frontostriatal glutamate neuroadaptations during spontaneous nicotine withdrawal.
Topics: Adaptation, Physiological; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cognition; Conditioning, Operant; Corpus Striatum; Discrimination, Psychological; Frontal Lobe; Glutamic Acid; Male; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Substance Withdrawal Syndrome; Synaptic Transmission | 2020 |
Direct administration of ifenprodil and citalopram into the nucleus accumbens inhibits cue-induced nicotine seeking and associated glutamatergic plasticity.
Topics: Animals; Citalopram; Cues; Dendritic Spines; Drug-Seeking Behavior; Excitatory Amino Acid Antagonists; Extinction, Psychological; Glutamic Acid; Male; Neuronal Plasticity; Neurons; Nicotine; Nucleus Accumbens; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Selective Serotonin Reuptake Inhibitors; Self Administration | 2020 |
Amino acid systems in the interpeduncular nucleus are altered in a sex-dependent manner during nicotine withdrawal.
Topics: Amino Acids; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Interpeduncular Nucleus; Male; Nicotine; Receptors, Corticotropin-Releasing Hormone; Serotonin; Substance Withdrawal Syndrome | 2022 |
Prenatal Hypoxia Affects Nicotine Consumption and Withdrawal in Adult Rats via Impairment of the Glutamate System in the Brain.
Topics: Animals; Dopamine; Glutamic Acid; Hypoxia; Mecamylamine; Nicotine; Nicotinic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Nicotinic; Tobacco Use Disorder; Ventral Tegmental Area | 2022 |