nicotine has been researched along with gamma-aminobutyric acid in 197 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (14.72) | 18.7374 |
| 1990's | 32 (16.24) | 18.2507 |
| 2000's | 80 (40.61) | 29.6817 |
| 2010's | 50 (25.38) | 24.3611 |
| 2020's | 6 (3.05) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
| Jensen, AA; Liljefors, T; Zlotos, DP | 1 |
| Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| McKenzie, GM; Viik, K | 1 |
| Cahill, MA; Florey, E; Rathmayer, M | 1 |
| Brenner, M; Drum, P; Jurna, I | 1 |
| Haefely, W; Jalfre, M; Ruch-Monachon, MA | 1 |
| Ahnert-Hilger, G; Wiedenmann, B | 1 |
| Fung, YK; Lau, YS | 1 |
| Gallagher, JP; Phelan, KD; Shinnick-Gallagher, P | 1 |
| Antonelli, T; Beani, L; Bianchi, C; Ferraro, L; Morari, M; Nordberg, A; Spalluto, P; Tanganelli, S | 1 |
| Aguirre, JA; Fuxe, K; Méndez-Franco, J; Pérez de la Mora, M; Salceda, R | 1 |
| Dohi, T; Kitayama, S; Morita, K; Tsujimoto, A | 1 |
| Collins, AC; Freund, RK; Luntz-Leybman, V | 1 |
| Marchi, M; Paudice, P; Pittaluga, A; Raiteri, M | 1 |
| Beani, L; Bianchi, C; Ferraro, L; Nilsson, L; Nordberg, A; Romanelli, L; Spalluto, P; Sundwall, A; Tanganelli, S | 1 |
| Collins, AC; Freund, RK; Jungschaffer, DA; Wehner, JM | 1 |
| Iasnetsov, VS; Novikov, VE | 1 |
| Cherniack, NS; Deal, EC; Haxhiu, MA; Mitra, J; Norcia, MP; Van Lunteren, E | 1 |
| Ghazi, H; Osborne, NN | 1 |
| Bland, BH; Konopacki, J; Roth, SH | 1 |
| Garcha, HS; Rose, IC; Stolerman, IP | 1 |
| Benson, JA | 1 |
| Fung, YK; Reed, JA | 1 |
| Ishikawa, Y; Kantoh, M; Kusunoki, M; Takahashi, T; Utsunomiya, J; Yamamura, T | 1 |
| Bickford-Wimer, PC; de la Garza, R; Freedman, R; Hoffer, BJ | 1 |
| Brus, R; Opiełka, L; Szkilnik, R | 1 |
| Cherniack, NS; Haxhiu, MA; Mitra, J; Prabhakar, NR; van Lunteren, E | 1 |
| Dryden, WF; Harvey, AL | 1 |
| Olenev, SN | 1 |
| Barker, JL; Mathers, DA | 1 |
| Levine, AS; Morley, JE; Silvis, SE | 1 |
| Crossman, AR; Lee, LA; Slater, P | 1 |
| Beaujouan, JC; Besson, MJ; Glowinski, J; Michelot, R; Torrens, Y | 1 |
| Kusunoki, M; Tanaka, C; Taniyama, K | 1 |
| Kusunoki, M; Saito, N; Tanaka, C; Taniyama, K | 1 |
| Breese, GR; Criswell, HE; Duncan, GE; Keir, WJ; McCown, TJ; Morrow, AL; Simson, PE | 1 |
| Besson, MJ; Kayadjanian, N; Menétrey, A; Rétaux, S | 1 |
| Chiappinelli, VA; McMahon, LL; Yoon, KW | 1 |
| Meyer, EM; Sjak-Shie, NN | 1 |
| Bai, D; Sattelle, DB | 1 |
| Changeux, JP; Léna, C; Mulle, C | 1 |
| Bocchi, R; Caffarri, G; Capretti, L; Chiodera, P; Coiro, V; Marcato, A; Rossi, G; Volpi, R | 1 |
| Beani, L; Bianchi, C; Ferraro, L; Morari, M; Simonato, M; Spalluto, G; Tanganelli, S | 1 |
| Breese, GR; Criswell, HE; Yang, X | 1 |
| McGehee, DS; Role, LW | 1 |
| Changeux, JP; Léna, C | 1 |
| Bertolino, M; Gillis, RA; Kellar, KJ; Vicini, S | 1 |
| Akaike, N; Rhee, JS; Shimura, M; Sorimachi, M | 1 |
| Albuquerque, EX; Alkondon, M; Barbosa, CT; Pereira, EF | 1 |
| Breese, CR; Dunwiddie, TV; Frazier, CJ; Freedman, R; Leonard, S; Rollins, YD | 1 |
| Alcayaga, J; Arroyo, J; Iturriaga, R; Varas, R; Zapata, P | 1 |
| Changeux, JP; Collins, AC; Grady, S; Lu, Y; Marks, MJ; Picciotto, M | 1 |
| Wickelgren, I | 1 |
| Harada, K; Kakizaki, A; Kashimoto, T; Kudo, K; Miyate, Y; Tachikawa, E; Takahashi, E | 1 |
| Dani, JA; Fisher, JL; Gray, R; Radcliffe, KA | 1 |
| Beckman, ML; Covernton, PJ; Fenster, CP; Hicks, JH; Lester, RA; Quick, MW | 1 |
| Collins, AC; Lu, Y; Marks, MJ | 1 |
| Chiappinelli, VA; Zhu, PJ | 2 |
| Bernardi, G; Berretta, N; Grillner, P; Mercuri, NB; Svensson, TH | 1 |
| Fujii, S; Jia, Y; Sumikawa, K; Yang, A | 1 |
| Ito, E; Tojima, T | 1 |
| Mansvelder, HD; McGehee, DS | 1 |
| Köfalvi, A; Sperlágh, B; Vizi, ES; Zelles, T | 1 |
| Arce, C; González, MP; López, E; Oset-Gasque, MJ; Vicente, S | 1 |
| Henderson, S; Malcolm, R; McCormick, K; Myrick, H | 1 |
| Besheer, J; Bevins, RA; Pickett, KS | 1 |
| Champagnat, J; Menini, C; Silva-Barrat, C; Szente, M; Velluti, JC | 1 |
| Hulo, S; Muller, D | 1 |
| Barazangi, N; Role, LW | 1 |
| Cherubini, E; Maggi, L; Sher, E | 1 |
| Akaike, N; Katsurabayashi, S; Kiyosawa, A; Pang, ZP | 1 |
| Gauglitz, S; Pflüger, HJ | 1 |
| Engberg, G; Erhardt, S; Schwieler, L | 1 |
| Singer, HS | 1 |
| Keath, JR; Mansvelder, HD; McGehee, DS | 1 |
| Albuquerque, EX; Alkondon, M; Aracava, Y; Eisenberg, HM; Maelicke, A; Pereira, EF; Santos, MD | 1 |
| Markou, A; Paterson, NE | 1 |
| Domínguez, Mdel C; Drucker-Colín, R; Guzmán-Marín, R; Mihailescu, S | 1 |
| Minami, K; Okamoto, T; Shibuya, I; Shigematsu, A; Shiraishi, M; Ueno, S; Ueta, Y; Uezono, Y; Yanagihara, N | 1 |
| Rashid, MH; Ueda, H | 1 |
| Jo, YH; Role, LW | 1 |
| Brussaard, AB; de Rover, M; Kits, KS; Lodder, JC; Schoffelmeer, AN | 1 |
| Gu, JG; Nakatsuka, T; Papke, R; Takeda, D | 1 |
| Chiappinelli, VA; Nong, Y; Sorenson, EM | 1 |
| Baxi, S; Evans, C; Irnaten, M; Mendelowitz, D; Venkatesan, P; Wang, J; Wang, X | 1 |
| Fickbohm, D; Trimmer, BA | 1 |
| Baxi, S; Evans, C; Mendelowitz, D; Neff, RA; Wang, J | 1 |
| Alreja, M; Hajszan, T; Leranth, C; Wu, M | 1 |
| CASIDA, LE; ROSENFIELD, R | 1 |
| HOBBIGER, F | 1 |
| KOSHINO, F | 1 |
| Froestl, W; Markou, A; Paterson, NE | 2 |
| Evans, C; Mendelowitz, D; Wang, X | 1 |
| Daikoku, S; Funabashi, T; Kimura, F; Mitsushima, D; Sano, A; Shinohara, K; Suyama, K | 1 |
| Cooper, E; Wheeler, DG | 1 |
| Brussaard, AB; de Rover, M; Lodder, JC; Mansvelder, HD; Schoffelmeer, AN; Wardeh, G | 1 |
| Changeux, JP; Cordero-Erausquin, M; Faure, P; Pons, S | 1 |
| Kalra, PS; Kalra, SP | 1 |
| Evans, C; Mendelowitz, D; Neff, RA; Simmens, SJ | 1 |
| Brussaard, AB; De Rover, M; Lodder, JC; Schoffelmeer, AN | 1 |
| Markou, A; Paterson, NE; Semenova, S | 1 |
| Lee, S; Zheng, JJ; Zhou, ZJ | 1 |
| Campusano, JM; Jiang, SA; O'Dowd, DK; Su, H | 1 |
| Batini, C; Champagnat, J; Silva-Barrat, C; Szente, M; Velluti, J | 1 |
| Funabashi, T; Kimura, F; Mitsushima, D; Sano, A | 1 |
| Evans, SP; Francis, MM; Jensen, M; Madsen, DM; Mancuso, J; Maricq, AV; Norman, KR | 1 |
| Culligan, K; Kosten, T; Mouratidis, M; Sofuoglu, M; Yoo, S | 1 |
| Ciraulo, DA; Hennen, J; Jensen, JE; Ke, Y; Knapp, C; Kwak, T; Meyer, AA; Nassar, LE; Renshaw, PF; Sarid-Segal, O; Streeter, CC | 1 |
| Hamaue, N; Jia, Y; Sumikawa, K; Yamazaki, Y | 1 |
| Barik, J; Wonnacott, S | 1 |
| Gong, Y; Govindarajan, N; Liu, JJ; Mohila, CA; Onn, SP | 1 |
| Jo, YH; Role, LW; Wiedl, D | 1 |
| Aosaki, T; Ishii, K; Miura, M; Sumikawa, K | 1 |
| DeChon, J; Hu, G; Hu, J; Liu, Q; Wu, J; Yan, KC | 1 |
| Cattaneo, A; Cherubini, E; Rosato-Siri, M | 1 |
| Changeux, JP; Cherubini, E; Le Magueresse, C; Safiulina, V | 1 |
| Boulter, J; Glykys, J; Klaassen, A; Labarca, C; Maguire, J; Mody, I | 1 |
| Berg, DK; Liu, Z; Neff, RA | 1 |
| Deighton, N; Gibson, G; Hsieh, WP; Hunt, P; Passador-Gurgel, G | 1 |
| Costy-Bennett, S; Fregosi, RF; Luo, Z; McMullen, NT | 1 |
| Guo, A; Peng, Y | 1 |
| Liu, Z; Murphy, TH; Nawa, H; Otsu, Y; Vasuta, C | 1 |
| Barrett, LE; Iacoviello, MP; Keath, JR; Mansvelder, HD; McGehee, DS | 1 |
| Aoki, C; Disney, AA; Hawken, MJ | 1 |
| Chen, H; Sharp, BM; Wang, F | 1 |
| Parker, R; Vincler, M; Wittenauer, S; Young, T | 1 |
| O'Dell, LE | 1 |
| Du, C; Hancock, M; Mertz, M; Role, LW; Talmage, DA; Zhong, C | 1 |
| Ahtee, L; Airavaara, M; Leiviskä, R; Piepponen, TP; Relander, TR; Tuominen, RK; Vihavainen, T | 1 |
| Costa, E; Guidotti, A; Hajos, M; Maloku, E; Pibiri, F; Satta, R; Zhubi, A | 1 |
| Fukuma, G; Hase, K; Hirose, S; Kaneko, S; Kijima, H; Kishi, A; Kojima, T; Mitsudome, A; Miura, Y; Mori, F; Ohno, H; Okada, M; Saito, R; Sato, A; Takahara, T; Takano, Y; Tomiyama, M; Ueno, S; Wakabayashi, K; Yoshida, S; Zhu, G | 1 |
| Brunzell, DH; Grady, SR; King, SL; Lindstrom, JM; Marks, MJ; McIntosh, JM; Mineur, YS; Picciotto, MR | 1 |
| Al-Wadei, HA; Plummer, HK; Schuller, HM | 1 |
| Constantinou, S; Fern, R | 1 |
| Ben-Ari, Y; Dehorter, N; Eusebio, A; Guigoni, C; Hammond, C; Hirsch, J; Lopez, C | 1 |
| Ishibashi, M; Kohlmeier, KA; Leonard, CS | 1 |
| Cherubini, E; Griguoli, M; Ragozzino, D; Scuri, R | 1 |
| Chen, H; Matta, SG; Sharp, BM; Wu, X; Yu, G | 1 |
| Fadel, J; Pasumarthi, RK | 1 |
| Akaike, H; Akaike, N; Hori, N; Ito, Y; Jang, II; Ogawa, S | 1 |
| Dani, JA; Pidoplichko, VI; Tang, J; Zhang, TA | 1 |
| Fu, XW; Spindel, ER; Wood, K | 1 |
| Kauer, JA; Murali, M; Niehaus, JL | 1 |
| Bailey, CD; De Biasi, M; Fletcher, PJ; Lambe, EK | 1 |
| Carloni, P; Cherubini, E; Giorgetti, A; Griguoli, M; Maul, A; Nguyen, C | 1 |
| Feng, YH; Li, Y; Peng, Y; Sun, YP; Yu, DQ; Zhang, DM; Zhang, WQ; Zhao, J | 1 |
| Banerjee, D; Finn, MG; Froestl, W; Guery, S; Kaupmann, K; Markou, A; Paterson, NE; Vlachou, S | 1 |
| Bois, F; Cosgrove, KP; Esterlis, I; Krystal, JH; Mason, GF; O'Malley, SS | 1 |
| Buhlman, L; Jin, G; Khan, GM; Lukas, RJ; McIntosh, JM; Nichols, RA; Whiteaker, P; Wu, J; Yang, K | 1 |
| Dong, E; Guidotti, A; Kadriu, B; Maloku, E; Pibiri, F; Satta, R; Zhubi, A | 1 |
| Fujita, T; Kumamoto, E; Liu, T | 1 |
| Booker, TK; Grady, SR; Heinemann, SF; McGranahan, TM; Patzlaff, NE | 1 |
| Herman, AI; McKee, SA; Sofuoglu, M; Waters, AJ | 1 |
| Ma, L; Meng, X; Tang, H; Wang, L; Xu, P; Yao, Y; Yu, H; Zhang, D | 1 |
| Al-Wadei, HA; Al-Wadei, MH; Schuller, HM; Ullah, MF | 1 |
| Biundo, F; Cavallero, A; Govoni, S; Grilli, M; Lanni, C; Marchi, M; Mura, E; Olivero, G; Preda, S; Salamone, A; Zappettini, S | 1 |
| Al-Wadei, HA; Al-Wadei, MH; Schuller, HM | 2 |
| Patel, AB; Shameem, M | 1 |
| Buczynski, MW; Natividad, LA; O'Dell, LE; Parsons, LH; Torres, OV | 1 |
| Enjin, A; Eriksson, A; Gezelius, H; Kullander, K; Leão, KE; Leão, RN; Loew, LM; Mikulovic, S; Munguba, H; Patra, K; Tort, AB | 1 |
| Cohen, BN; Fonck, C; Grady, SR; Laverty, DC; Lester, HA; Lindstrom, JM; Marks, MJ; McIntosh, JM; McKinney, S; O'Neill, HC; Patzlaff, NE | 1 |
| D'Souza, MS; Markou, A | 1 |
| Gomez, DR; Liao, Z; Wang, H | 1 |
| Cohen, BN; Henley, BM; Lester, HA; Mackey, ED; Srinivasan, R; Williams, BA; Wold, BJ; Xiao, C | 1 |
| Ebihara, K; Kobayashi, M; Koshikawa, N; Yamamoto, K | 1 |
| Govoni, S; Grilli, M; Marchi, M; Mura, E; Olivero, G; Preda, S; Salamone, A; Zappettini, S | 1 |
| De Vries, TJ; Lubbers, BR; Schetters, D; Smit, AB; Spijker, S; van Mourik, Y | 1 |
| Damborsky, JC; Griffith, WH; Winzer-Serhan, UH | 1 |
| Chavarría, K; Garduño, J; Hernández-López, S; Hernández-Vázquez, F; Mihailescu, SP | 1 |
| Garcia-Bereguiain, MA; Gonzalez-Islas, C; O'Flaherty, B; Wenner, P | 1 |
| Aoyama, Y; Hattori, T; Hiramatsu, M; Kim, HC; Mamiya, T; Mouri, A; Nabeshima, T; Nagai, T; Sakakibara, N; Shimato, A; Soh, Y; Toriumi, K; Ueda, E; Yamada, K | 1 |
| Al-Wadei, HA; Al-Wadei, MH; Banerjee, J; Schuller, HM | 1 |
| Buczynski, MW; Chang, JW; Cravatt, BF; Herman, MA; Hsu, KL; Irimia, C; Natividad, LA; Niphakis, MJ; Parsons, LH; Polis, IY; Pugh, H; Roberto, M | 1 |
| Pilarski, JQ; Revill, AL; Vincen-Brown, MA | 1 |
| Chu, CP; Jin, H; Qiu, DL; Xu, Q; Zhang, BB; Zhang, KM; Zhao, GY | 1 |
| Dong, W; He, X; Jiao, Z; Lu, J; Wang, H; Xu, D; Yu, Y; Zhang, C; Zhang, Z | 1 |
| Fregosi, RF; Levine, RB; Wollman, LB | 1 |
| Endres, T; Lessmann, V; Meis, S; Munsch, T | 1 |
| Bading, H; Baur, K; Bengtson, CP; Bernardi, RE; Hach, A; Spanagel, R | 1 |
| Akimoto, H; Kobayashi, D; Michiyama, Y; Negishi, A; Nemoto, T; Oshima, S | 1 |
| Aidelbaum, R; Choueiry, J; de la Salle, S; Hadjis, E; Hyde, M; Jaworska, N; Knott, V; Nelson, R; Smith, D | 1 |
| Deperrois, N; Gutkin, B; Moiseeva, V | 1 |
| de Abreu, GR; de Souza Spinosa, H; Faria Waziry, PA; Flório, JC; Fukushima, AR; Lebrun, I; Moreira, N; Petrocelli, BM; Reis-Silva, TM; Ricci, EL; Sandini, TM; Zaccarelli-Magalhães, J | 1 |
| Mabandla, MV; Rakgantsho, C | 1 |
| Candiotti, KA; Gitlin, M; Rodriguez-Blanco, YF; Sevilla, A; Su, C; Weller, R; Wu, J; Yang, J; Zhang, Y; Zheng, C | 1 |
| Besson, M; Grieder, TE; Maal-Bared, G; Maskos, U; Pons, S; van der Kooy, D | 1 |
| Carcoba, LM; DeBiasi, M; Mendez, IA; O'Dell, LE; Ortegon, S; Uribe, KP | 1 |
| Goldberg, JA; Johansson, Y; Malgady, JM; Matityahu, L; Plotkin, JL; Schirelman, M; Silberberg, G; Wilking, JA | 1 |
| Di Ciano, P; Hendershot, CS; Le Foll, B | 1 |
| Beier, KT; de Jong, JW; Du, JX; Lammel, S; Liu, C; Tang, LW; Tose, AJ; Verharen, JPH; Zhu, Y | 1 |
| Borges-Martins, VPP; Castro, NG; Damascena, ACO; de Melo Reis, RA; Ferraz, G; Gonçalves, LAC; Kubrusly, RCC; Manhães, AC; Peixoto-Rodrigues, MC; Souto, AC; Tempone, MH; Ventura, ALM | 1 |
13 review(s) available for nicotine and gamma-aminobutyric acid
| Article | Year |
|---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
Modulation of excitatory transmission at the rat medial vestibular nucleus synapse.
Topics: Animals; GABA Antagonists; gamma-Aminobutyric Acid; Histamine Antagonists; Muscarine; Neurotransmitter Agents; Nicotine; Rats; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Vestibular Nuclei | 1992 |
Chemically induced ion channels in nerve cell membranes.
Topics: Acetylcholine; Animals; Barbiturates; Benzodiazepines; Cell Membrane; Cells, Cultured; Central Nervous System; Convulsants; Culture Techniques; Decapodiformes; Electricity; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Autonomic; Ganglia, Sympathetic; Glutamates; Glutamic Acid; Glycine; Ion Channels; Mollusca; Muscarine; Neurons; Nicotine; Pentobarbital; Spinal Cord; Vertebrates | 1982 |
Central regulation of gastric acid secretion: the role of neuropeptides.
Topics: Animals; Bombesin; Calcitonin; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; gamma-Aminobutyric Acid; Gastric Acid; Gastrins; Humans; Hypothalamus; Naphazoline; Neurotensin; Nicotine; Norepinephrine; Peptides; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Somatostatin; Thyrotropin-Releasing Hormone | 1982 |
The neuroanatomical specificity of ethanol action on ligand-gated ion channels: a hypothesis.
Topics: Animals; Brain; Ethanol; gamma-Aminobutyric Acid; Glycine; Humans; Ion Channels; Ligands; Models, Neurological; Muscimol; N-Methylaspartate; Nicotine; Receptors, GABA-A | 1993 |
Presynaptic ionotropic receptors.
Topics: Animals; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Ion Channel Gating; Nicotine; Presynaptic Terminals; Receptors, Cell Surface | 1996 |
The treatment of tics.
Topics: Adrenergic alpha-Agonists; Androgen Antagonists; Anti-Bacterial Agents; Antipsychotic Agents; Autoimmune Diseases; Botulinum Toxins, Type A; Cannabinoids; Clinical Trials as Topic; Cross-Over Studies; Dopamine Agonists; Dopamine Antagonists; Double-Blind Method; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Humans; Immunoglobulins, Intravenous; Neurosurgical Procedures; Nicotine; Randomized Controlled Trials as Topic; Receptors, Dopamine; Receptors, Nicotinic; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Streptococcal Infections; Tics; Tourette Syndrome | 2001 |
Overlapping and interactive pathways regulating appetite and craving.
Topics: Adipose Tissue; Appetite Regulation; Body Weight; Cannabinoid Receptor Modulators; Energy Intake; gamma-Aminobutyric Acid; Ghrelin; Humans; Hypothalamus; Intracellular Signaling Peptides and Proteins; Leptin; Narcotics; Neuropeptides; Nicotine; Orexins; Peptide Hormones; Signal Transduction; Stomach; Ventromedial Hypothalamic Nucleus | 2004 |
A psychobiological framework of the substrates that mediate nicotine use during adolescence.
Topics: Adolescent; Age Factors; Animals; Brain Chemistry; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Humans; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Tobacco Use Disorder; Ventral Tegmental Area | 2009 |
Neuroimaging insights into the role of cortical GABA systems and the influence of nicotine on the recovery from alcohol dependence.
Topics: Alcoholism; Brain; Clinical Trials as Topic; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Humans; Nicotine; Nicotinic Agonists; Radionuclide Imaging; Receptors, GABA-A; Smoking | 2011 |
Gamma-amino butyric acid inhibits the nicotine-imposed stimulatory challenge in xenograft models of non-small cell lung carcinoma.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Division; gamma-Aminobutyric Acid; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Nicotine; Receptors, Nicotinic; Xenograft Model Antitumor Assays | 2012 |
The "stop" and "go" of nicotine dependence: role of GABA and glutamate.
Topics: Animals; Behavior, Animal; Brain; Conditioning, Psychological; Dopamine; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Limbic System; Nicotine; Nicotinic Antagonists; Receptors, Glutamate; Reinforcement, Psychology; Smoking Cessation; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2013 |
Therapeutic Potential of Histamine H3 Receptors in Substance Use Disorders.
Topics: Acetylcholine; Animals; Autoreceptors; Central Nervous System Stimulants; Dopamine; Ethanol; gamma-Aminobutyric Acid; Histamine; Histamine H3 Antagonists; Ligands; Nicotine; Norepinephrine; Receptors, Histamine H3; Substance-Related Disorders | 2022 |
3 trial(s) available for nicotine and gamma-aminobutyric acid
| Article | Year |
|---|---|
Effects of tiagabine in combination with intravenous nicotine in overnight abstinent smokers.
Topics: Adult; Anticonvulsants; Arousal; Attention; Blood Pressure; Brain; Cross-Over Studies; Double-Blind Method; Female; gamma-Aminobutyric Acid; Heart Rate; Humans; Male; Neuropsychological Tests; Nicotine; Nipecotic Acids; Reward; Smoking Cessation; Substance Withdrawal Syndrome; Tiagabine | 2005 |
Prefrontal GABA levels in cocaine-dependent subjects increase with pramipexole and venlafaxine treatment.
Topics: Adult; Antidepressive Agents, Second-Generation; Antioxidants; Benzothiazoles; Cocaine-Related Disorders; Cyclohexanols; Double-Blind Method; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nicotine; Pramipexole; Prefrontal Cortex; Protons; Retrospective Studies; Thiazoles; Time Factors; Venlafaxine Hydrochloride | 2005 |
Effects of pregabalin on smoking behavior, withdrawal symptoms, and cognitive performance in smokers.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Female; gamma-Aminobutyric Acid; Humans; Male; Nicotine; Outpatients; Pregabalin; Psychomotor Performance; Smoking Cessation; Smoking Prevention; Substance Withdrawal Syndrome; Tobacco Use Disorder; Young Adult | 2012 |
181 other study(ies) available for nicotine and gamma-aminobutyric acid
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Pharmacological characteristics and binding modes of caracurine V analogues and related compounds at the neuronal alpha7 nicotinic acetylcholine receptor.
Topics: Aconitine; Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Animals; Binding Sites; Binding, Competitive; Cell Line; Humans; Ion Channels; Ligands; Membrane Potentials; Mice; Models, Molecular; Molecular Structure; Mutation; Neurons; Nicotinic Antagonists; Radioligand Assay; Rats; Receptors, Nicotinic; Receptors, Serotonin, 5-HT3; Recombinant Fusion Proteins; Serotonin 5-HT3 Receptor Antagonists; Structure-Activity Relationship | 2007 |
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship | 2010 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Chemically induced chorieform activity: antagonism by GABA and EEG patterns.
Topics: Allyl Compounds; Aminobutyrates; Animals; Aspartic Acid; Brain Chemistry; Carbachol; Cats; Caudate Nucleus; Cerebral Cortex; Chorea; Corpus Striatum; Drug Antagonism; Electroencephalography; gamma-Aminobutyric Acid; Glutamates; Glycine; Homocysteine; Male; Neostigmine; Nicotine; Physostigmine; Picrotoxin; Rats; Tubocurarine | 1975 |
Excitatory actions of GABA and of acetyl-choline in sea urchin tube feet.
Topics: Acetylcholine; Aminobutyrates; Atropine; Butyrylthiocholine; Carbachol; Chlorides; Decamethonium Compounds; Gallamine Triethiodide; gamma-Aminobutyric Acid; Hexamethonium Compounds; Muscle Contraction; Muscles; Neostigmine; Nicotine; Peripheral Nerves; Physostigmine; Quaternary Ammonium Compounds; Sea Urchins; Sodium | 1975 |
Abolition of spinal motor disturbance by injections of dopamine receptor agonists, atropin and GABA into the caudate nucleus.
Topics: Aminobutyrates; Animals; Atropine; Caudate Nucleus; Female; gamma-Aminobutyric Acid; Hydroxydopamines; Injections; Male; Motor Neurons; Muscarine; Nicotine; Rats; Receptors, Dopamine; Reflex; Reserpine; Spinal Cord; Substantia Nigra | 1978 |
Drugs and PGO waves in the lateral geniculate body of the curarized cat. IV. The effects of acetylcholine, GABA and benzodiazepines on PGO wave activity.
Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Acetylcholine; Aminobutyrates; Animals; Arecoline; Atropine; Benzodiazepines; Cats; Chlordiazepoxide; Electroencephalography; gamma-Aminobutyric Acid; Geniculate Bodies; Mecamylamine; Nicotine; Occipital Lobe; Physostigmine; Pons | 1976 |
The amphicrine pancreatic cell line, AR42J, secretes GABA and amylase by separate regulated pathways.
Topics: Amylases; Animals; Biological Transport; Calcium; Carbachol; Carcinoma; Dexamethasone; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Membrane Potentials; Nicotine; Pancreas; Potassium; Rats; Tumor Cells, Cultured | 1992 |
Chronic effects of nicotine on mesolimbic dopaminergic system in rats.
Topics: alpha-Methyltyrosine; Animals; Dextroamphetamine; Dopamine; Dopamine Antagonists; gamma-Aminobutyric Acid; Injections; Limbic System; Male; Methyltyrosines; Motor Activity; Nicotine; Nucleus Accumbens; Potassium; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Nicotinic; Spiperone; Tyrosine 3-Monooxygenase | 1992 |
Effect of acute and subchronic nicotine treatment on cortical efflux of [3H]-D-aspartate and endogenous GABA in freely moving guinea-pigs.
Topics: Acetylcholine; Animals; Aspartic Acid; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Guinea Pigs; Injections, Intraventricular; Injections, Subcutaneous; Male; Mecamylamine; Methysergide; Naloxone; Nicotine; Receptors, GABA-A; Receptors, Nicotinic | 1991 |
Neurochemical effects of nicotine on glutamate and GABA mechanisms in the rat brain.
Topics: Animals; Brain; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Male; Neurons; Nicotine; Rats; Rats, Inbred Strains; Tritium | 1991 |
Enhancement by GABA of the stimulation-evoked catecholamine release from cultured bovine adrenal chromaffin cells.
Topics: Acetylcholine; Adrenal Glands; Animals; Bicuculline; Caffeine; Calcium; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Nicotine; Picrotoxin; Potassium; Receptors, GABA-A; Veratridine | 1990 |
Nicotine interferes with GABA-mediated inhibitory processes in mouse hippocampus.
Topics: Animals; Bicuculline; Electric Stimulation; Female; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred DBA; Nicotine; Pyramidal Tracts; Time Factors | 1990 |
Muscarinic receptors mediating inhibition of gamma-aminobutyric acid release in rat corpus striatum and their pharmacological characterization.
Topics: Acetylcholine; Animals; Cells, Cultured; Corpus Striatum; gamma-Aminobutyric Acid; Male; Nicotine; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes | 1990 |
Effect of nicotine on the release of acetylcholine and amino acids in the brain.
Topics: Acetylcholine; Animals; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Nicotine; Rats | 1989 |
Evidence for modulation of GABAergic neurotransmission by nicotine.
Topics: Action Potentials; Allylglycine; Animals; Bicuculline; Brain Chemistry; Female; Flunitrazepam; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred DBA; Nicotine; Receptors, GABA-A | 1988 |
[The GABA-ergic system and brain edema].
Topics: Animals; Anti-Anxiety Agents; Benactyzine; Benzodiazepines; Benzodiazepinones; Brain Edema; Brain Injuries; Diazepam; Drug Evaluation, Preclinical; Drug Interactions; Female; gamma-Aminobutyric Acid; Male; Nicotine; Parasympatholytics; Phentolamine; Picrotoxin; Rats; Receptors, GABA-A | 1985 |
Medullary effects of nicotine and GABA on tracheal smooth muscle tone.
Topics: Administration, Topical; Airway Resistance; Animals; Bicuculline; Carbon Dioxide; Cats; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hexamethonium; Hexamethonium Compounds; Lidocaine; Male; Medulla Oblongata; Nicotine; Phrenic Nerve; Trachea | 1986 |
Agonist-induced stimulation of inositol phosphates in primary rabbit retinal cultures.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Carbachol; Cells, Cultured; Clonidine; Dopamine; gamma-Aminobutyric Acid; Inositol Phosphates; Isoproterenol; Neurotransmitter Agents; Nicotine; Norepinephrine; Rabbits; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Receptors, Serotonin; Retina; Serotonin; Sugar Phosphates; Tetrahydronaphthalenes | 1988 |
Evidence that activation of in vitro hippocampal theta rhythm only involves muscarinic receptors.
Topics: Animals; Carbachol; Dopamine; Electroencephalography; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Nicotine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Serotonin; Theta Rhythm | 1988 |
Midazolam cue in rats: effects of Ro 15-1788 and picrotoxin.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Male; Midazolam; Nicotine; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A | 1986 |
Bicuculline blocks the response to acetylcholine and nicotine but not to muscarine or GABA in isolated insect neuronal somata.
Topics: Acetylcholine; Animals; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; Grasshoppers; In Vitro Techniques; Membrane Potentials; Muscarine; Neurons; Nicotine; Reference Values | 1988 |
Effect of nicotine on central GABAergic system.
Topics: Animals; Apomorphine; Corpus Striatum; gamma-Aminobutyric Acid; Limbic System; Male; Muscimol; Nicotine; Nucleus Accumbens; Rats; Rats, Inbred Strains | 1988 |
Choledochal cyst. Its possible autonomic involvement in the bile duct.
Topics: Acetylcholine; Cholecystokinin; Common Bile Duct; Common Bile Duct Diseases; Cysts; Egg Yolk; gamma-Aminobutyric Acid; Humans; Muscle Contraction; Nicotine | 1987 |
Heterogeneity of nicotine actions in the rat cerebellum: an in vivo electrophysiologic study.
Topics: Acetylcholine; Action Potentials; Animals; Cerebellum; Curare; gamma-Aminobutyric Acid; Hexamethonium Compounds; Male; Nicotine; Rats; Receptors, Nicotinic | 1987 |
Behaviour of rats and brain biochemical changes under the effect of kainic acid, dopamine, nicotine and muscarine administered into the caudate nuclei.
Topics: Acetylcholine; Animals; Brain; Caudate Nucleus; Cognition; Dopamine; gamma-Aminobutyric Acid; Kainic Acid; Male; Motor Activity; Muscarine; Nicotine; Rats; Rats, Inbred Strains | 1985 |
Influence of central chemoreceptor afferent inputs on respiratory muscle activity.
Topics: Animals; Cats; Chemoreceptor Cells; Cold Temperature; Diaphragm; Electromyography; Female; gamma-Aminobutyric Acid; Intercostal Muscles; Male; Medulla Oblongata; Muscimol; Nicotine; Tidal Volume | 1985 |
Studies on the pharmacology of skeletal muscle in culture: specificity of receptors.
Topics: Acetylcholine; Animals; Atropine; Bungarotoxins; Carbachol; Chick Embryo; Culture Techniques; Decamethonium Compounds; Dimethylphenylpiperazinium Iodide; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Gallamine Triethiodide; gamma-Aminobutyric Acid; Histamine; Membrane Potentials; Methacholine Compounds; Muscles; Nicotine; Norepinephrine; Pilocarpine; Quaternary Ammonium Compounds; Receptors, Drug; Scopolamine; Serotonin; Succinylcholine | 1974 |
Influence of pharmacological agents on the growth of processes of spinal ganglion nerve cells in culture.
Topics: Acetylcholine; Animals; Arecoline; Atropine; Benactyzine; Chick Embryo; Choline; Decamethonium Compounds; Epinephrine; gamma-Aminobutyric Acid; Ganglia, Spinal; Glycine; Hexamethonium Compounds; In Vitro Techniques; Magnesium; Nerve Growth Factors; Nicotine; Norepinephrine; Parasympatholytics; Parasympathomimetics; Phentolamine; Potassium; Procaine; Propranolol; Serotonin; Sodium; Succinylcholine; Sympatholytics; Sympathomimetics; Tubocurarine | 1974 |
The role of the substantia nigra in a striatally-evoked motor response in the rat: effects of intranigral drugs and lesions.
Topics: Animals; Apomorphine; Atropine; Corpus Striatum; Electric Stimulation; Enkephalins; Female; Functional Laterality; gamma-Aminobutyric Acid; Kainic Acid; Mesencephalon; Movement; Nicotine; Pyrrolidines; Rats; Strychnine; Substance P; Substantia Nigra | 1981 |
Inhibitory effects of GABA, L-glutamic acid and nicotine on the potassium-evoked release of substance P in substantia nigra slices of the rat.
Topics: Animals; Calcium; gamma-Aminobutyric Acid; Glutamates; Immune Sera; In Vitro Techniques; Male; Nicotine; Picrotoxin; Potassium; Rats; Receptors, Nicotinic; Substance P; Substantia Nigra; Tetrodotoxin | 1981 |
Neuronal GABA release and GABA inhibition of ACh release in guinea pig urinary bladder.
Topics: Acetylcholine; Animals; Bicuculline; Electric Stimulation; Female; Furosemide; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Guinea Pigs; Male; Neurons; Nicotine; Tetrodotoxin; Tissue Distribution; Urinary Bladder | 1984 |
[Release of gamma-aminobutyric acid from cat colon].
Topics: Acetylcholine; Animals; Calcium; Cations, Divalent; Cats; Colon; Electric Stimulation; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nicotine; Tetrodotoxin | 1982 |
Stimulation by nicotine of the spontaneous release of [3H]gamma-aminobutyric acid in the substantia nigra and in the globus pallidus of the rat.
Topics: Animals; Benzazepines; Dopamine; gamma-Aminobutyric Acid; Globus Pallidus; In Vitro Techniques; Male; Neurons; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Stimulation, Chemical; Substantia Nigra; Sulpiride | 1994 |
Nicotinic receptor activation facilitates GABAergic neurotransmission in the avian lateral spiriform nucleus.
Topics: Animals; Bicuculline; Bungarotoxins; Carbachol; Chick Embryo; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Evoked Potentials; gamma-Aminobutyric Acid; Membrane Potentials; Mesencephalon; Neurons; Nicotine; Nicotinic Antagonists; Receptors, Nicotinic; Sodium Channel Blockers; Sodium Channels; Synaptic Transmission; Tetrodotoxin | 1994 |
Effects of chronic nicotine and pilocarpine administration on neocortical neuronal density and [3H]GABA uptake in nucleus basalis lesioned rats.
Topics: Animals; Cell Count; Cerebral Cortex; gamma-Aminobutyric Acid; Ibotenic Acid; Neurons; Nicotine; Pilocarpine; Rats; Rats, Wistar; Stereoisomerism; Substantia Innominata; Time Factors; Tritium | 1993 |
Neosurugatoxin blocks an alpha-bungarotoxin-sensitive neuronal nicotinic acetylcholine receptor.
Topics: Animals; Cockroaches; gamma-Aminobutyric Acid; Ganglia; In Vitro Techniques; Male; Membrane Potentials; Mollusk Venoms; Motor Neurons; Muscles; Neurotoxins; Nicotine; Nicotinic Antagonists; Receptors, Nicotinic; Sesquiterpenes; Snails; Snake Venoms; Vertebrates | 1993 |
Evidence for "preterminal" nicotinic receptors on GABAergic axons in the rat interpeduncular nucleus.
Topics: Animals; Axons; Cell Separation; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Mesencephalon; Nerve Endings; Neurons; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Synapses | 1993 |
Gamma-aminobutyric acid mediation of the inhibitory effect of endogenous opioids on the arginine vasopressin and oxytocin responses to nicotine from cigarette smoking.
Topics: Adult; Analysis of Variance; Arginine Vasopressin; Drug Interactions; Endorphins; gamma-Aminobutyric Acid; Humans; Male; Naloxone; Nicotine; Oxytocin; Smoking; Valproic Acid | 1993 |
5-Hydroxytryptamine-mediated effects of nicotine on endogenous GABA efflux from guinea-pig cortical slices.
Topics: Animals; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Guinea Pigs; Male; Neurotransmitter Agents; Nicotine; Serotonin | 1995 |
Nicotine-induced inhibition in medial septum involves activation of presynaptic nicotinic cholinergic receptors on gamma-aminobutyric acid-containing neurons.
Topics: Animals; Bicuculline; Dihydro-beta-Erythroidine; gamma-Aminobutyric Acid; Magnesium; Male; Neurons; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Presynaptic; Septum Pellucidum | 1996 |
Role of Ca2+ ions in nicotinic facilitation of GABA release in mouse thalamus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Action Potentials; Alkaloids; Animals; Arousal; Atropine; Azocines; Bacterial Toxins; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channel Blockers; Calcium Channels; Carbachol; Cations, Divalent; Cyanobacteria Toxins; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; GABA Antagonists; gamma-Aminobutyric Acid; Ion Transport; Lobeline; Marine Toxins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcystins; Neurons, Afferent; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Potassium; Pyridazines; Pyridines; Quinolizines; Receptors, GABA-A; Receptors, Nicotinic; Tetrodotoxin; Thalamic Nuclei | 1997 |
Nicotinic receptor mediates spontaneous GABA release in the rat dorsal motor nucleus of the vagus.
Topics: Acetylcholine; Animals; Brain Stem; gamma-Aminobutyric Acid; Nicotine; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Sympathetic Nervous System; Synaptic Transmission | 1997 |
Mechanisms of GABA- and glycine-induced increases of cytosolic Ca2+ concentrations in chick embryo ciliary ganglion cells.
Topics: Animals; beta-Alanine; Calcium; Chick Embryo; Chlorides; Cytosol; Fluorescent Dyes; Fura-2; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Parasympathetic; Glycine; Manganese; Nicotine; Potassium Channel Blockers; Potassium Chloride; Receptors, GABA-A; Spectrometry, Fluorescence | 1997 |
Neuronal nicotinic acetylcholine receptor activation modulates gamma-aminobutyric acid release from CA1 neurons of rat hippocampal slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Animals; Cells, Cultured; gamma-Aminobutyric Acid; Hippocampus; Humans; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Tetrodotoxin | 1997 |
Acetylcholine activates an alpha-bungarotoxin-sensitive nicotinic current in rat hippocampal interneurons, but not pyramidal cells.
Topics: Acetylcholine; Animals; Bungarotoxins; Electric Conductivity; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Male; Nicotine; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Presynaptic; RNA, Messenger | 1998 |
Selective activation of carotid nerve fibers by acetylcholine applied to the cat petrosal ganglion in vitro.
Topics: Acetylcholine; Animals; Carotid Body; Cats; Cholinergic Antagonists; Female; gamma-Aminobutyric Acid; Ganglia, Sensory; Ganglionic Stimulants; Glossopharyngeal Nerve; Male; Nerve Fibers; Nicotine; Serotonin | 1998 |
Pharmacological characterization of nicotinic receptor-stimulated GABA release from mouse brain synaptosomes.
Topics: Animals; Brain; Cells, Cultured; Female; gamma-Aminobutyric Acid; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Receptors, Nicotinic; Synaptosomes; Tritium | 1998 |
Drug may suppress the craving for nicotine.
Topics: Animals; Behavior, Animal; Brain; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine; gamma-Aminobutyric Acid; Humans; Nicotine; Papio; Smoking Cessation; Tobacco Use Disorder; Vigabatrin | 1998 |
Effects of ginseng saponins on responses induced by various receptor stimuli.
Topics: Adrenal Glands; Angiotensin II; Animals; Bradykinin; Catecholamines; Cattle; Central Nervous System Agents; Chromaffin Cells; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ginsenosides; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Muscarine; Muscarinic Agonists; Muscle Contraction; Neurotensin; Nicotine; Nicotinic Agonists; Panax; Plants, Medicinal; Receptors, Cell Surface; Saponins | 1999 |
Nicotinic modulation of glutamate and GABA synaptic transmission of hippocampal neurons.
Topics: Acetylcholine; Animals; Bungarotoxins; Cell Line; Electrophysiology; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Neurons; Nicotiana; Nicotine; Plants, Toxic; Rats; Receptors, Nicotinic; Synaptic Transmission | 1999 |
Desensitization of nicotinic receptors in the central nervous system.
Topics: Animals; Brain; Enzyme Inhibitors; gamma-Aminobutyric Acid; Indoles; Maleimides; Neurons; Nicotine; Oocytes; Patch-Clamp Techniques; Protein Kinase C; Receptors, Nicotinic; Xenopus | 1999 |
Desensitization of nicotinic agonist-induced [3H]gamma-aminobutyric acid release from mouse brain synaptosomes is produced by subactivating concentrations of agonists.
Topics: Animals; Brain Chemistry; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Perfusion; Stimulation, Chemical; Synaptosomes | 1999 |
Nicotine modulates evoked GABAergic transmission in the brain.
Topics: Animals; Brain; Chick Embryo; Electrophysiology; Evoked Potentials; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Ganglionic Stimulants; In Vitro Techniques; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Receptors, GABA-A; Receptors, Nicotinic; Synaptic Transmission; Thalamic Nuclei | 1999 |
Muscarinic receptors depress GABAergic synaptic transmission in rat midbrain dopamine neurons.
Topics: Animals; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Muscarine; Neural Inhibition; Neurons; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, GABA; Receptors, Muscarinic; Receptors, Nicotinic; Substantia Nigra; Synaptic Transmission; Ventral Tegmental Area | 2000 |
Nicotine reverses GABAergic inhibition of long-term potentiation induction in the hippocampal CA1 region.
Topics: Aconitine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Insecticides; Interneurons; Long-Term Potentiation; Muscimol; Neural Pathways; Nicotine; Nicotinic Agonists; Pyramidal Cells; Pyridines; Rats; Receptors, GABA-A; Receptors, Nicotinic | 2000 |
Bimodal effects of acetylcholine on synchronized calcium oscillation in rat cultured cortical neurons.
Topics: Acetylcholine; Animals; Calcium; Cell Communication; Cells, Cultured; Cerebral Cortex; Choline O-Acetyltransferase; gamma-Aminobutyric Acid; Glutamic Acid; Neurons; Nicotine; Nicotinic Agonists; Periodicity; Rats; Synaptic Transmission | 2000 |
Long-term potentiation of excitatory inputs to brain reward areas by nicotine.
Topics: Animals; Dopamine; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Long-Term Potentiation; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Presynaptic Terminals; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Synaptic Transmission; Ventral Tegmental Area | 2000 |
Long-lasting facilitation of 4-amino-n-[2,3-(3)H]butyric acid ([(3)H]GABA) release from rat hippocampal slices by nicotinic receptor activation.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Atropine; Calcium; Carrier Proteins; Chloride Channels; Drug Synergism; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Proteins; Membrane Transport Proteins; Muscarinic Antagonists; Neurons; Nicotine; Nicotinic Agonists; Nipecotic Acids; Organic Anion Transporters; Perfusion; Proline; Protein Kinase C; Rats; Rats, Wistar; Receptors, Nicotinic; Sodium Channel Blockers; Tritium | 2000 |
Nicotinic receptors mediate the release of amino acid neurotransmitters in cultured cortical neurons.
Topics: Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hexamethonium; Membrane Potentials; Neurons; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Receptors, Nicotinic | 2001 |
Gabapentin for misuse of homemade nicotine nasal spray.
Topics: Acetates; Administration, Intranasal; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Internet; Male; Middle Aged; Nebulizers and Vaporizers; Nicotine; Prescription Fees; Smoking Cessation; Tobacco Use Disorder | 2001 |
Nicotine-conditioned locomotor activity in rats: dopaminergic and GABAergic influences on conditioned expression.
Topics: 4-Aminobutyrate Transaminase; Animals; Benzazepines; Conditioning, Classical; Conditioning, Operant; Cues; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; gamma-Aminobutyric Acid; Male; Motor Activity; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Salicylamides; Vigabatrin | 2001 |
Muscarinic depression of synaptic transmission in the epileptogenic GABA withdrawal syndrome focus.
Topics: Action Potentials; Animals; Atropine Derivatives; Disease Models, Animal; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Male; Motor Cortex; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Reaction Time; Receptors, Muscarinic; Status Epilepticus; Substance Withdrawal Syndrome; Synaptic Transmission | 2001 |
Tetrodotoxin-sensitive enhancement of inhibition in CA1 pyramidal neurones by nicotine.
Topics: Acetylcholine; Animals; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Humans; Interneurons; Neural Inhibition; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Organ Culture Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Nicotinic; Smoking; Sodium Channels; Synaptic Transmission; Tetrodotoxin | 2001 |
Nicotine-induced enhancement of glutamatergic and GABAergic synaptic transmission in the mouse amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Bicuculline; Excitatory Amino Acid Antagonists; Female; Fetus; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Nicotine; Nicotinic Agonists; Olfactory Bulb; Pregnancy; Synaptic Transmission | 2001 |
Regulation of GABA release by nicotinic acetylcholine receptors in the neonatal rat hippocampus.
Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Animals, Newborn; Bicuculline; Bridged-Ring Compounds; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Insecticides; Membrane Potentials; Nicotine; Nicotinic Agonists; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Nicotinic; Spiro Compounds | 2001 |
Nicotine facilitates glycine release in the rat spinal dorsal horn.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha7 Nicotinic Acetylcholine Receptor; Anesthetics, Local; Animals; Bacterial Toxins; Bicuculline; Bungarotoxins; Calcium; Calcium Channels; Choline; Cyanobacteria Toxins; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Marine Toxins; Mecamylamine; Microcystins; Nerve Endings; Neural Inhibition; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nootropic Agents; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Nicotinic; Substantia Gelatinosa; Tetrodotoxin; Tropanes; Valine | 2001 |
Cholinergic transmission via central synapses in the locust nervous system.
Topics: Acetylcholine; Animals; Atropine; Bicuculline; Bungarotoxins; Carbachol; Crotonates; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Glutamic Acid; Grasshoppers; Interneurons; Muscimol; Neurons, Afferent; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Picrotoxin; Receptors, Nicotinic; Synapses; Synaptic Transmission; Tubocurarine | 2001 |
Excitatory and inhibitory responses of dopamine neurons in the ventral tegmental area to nicotine.
Topics: Action Potentials; Animals; Butyrates; Dopamine; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neural Inhibition; Neurons; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Glutamate; Synaptic Transmission; Tobacco Use Disorder; Up-Regulation; Ventral Tegmental Area | 2002 |
Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas.
Topics: Acetylcholinesterase; Action Potentials; Adolescent; Animals; Atropine; Cholinergic Antagonists; Cholinesterase Inhibitors; Dopamine; Electrophysiology; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Ganglionic Stimulants; Glutamic Acid; Humans; In Vitro Techniques; Insecticides; Mice; Muscarinic Antagonists; Neurons; Nicotine; Organothiophosphorus Compounds; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reward; Smoking; Synaptic Transmission; Ventral Tegmental Area | 2002 |
The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system.
Topics: Action Potentials; Allosteric Regulation; Animals; Antibodies, Monoclonal; Central Nervous System; Cholinesterases; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Postsynaptic Potentials; Galantamine; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; In Vitro Techniques; Neurons; Nicotine; Nootropic Agents; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Receptors, Glutamate; Synaptic Transmission; Time Factors | 2002 |
Increased GABA neurotransmission via administration of gamma-vinyl GABA decreased nicotine self-administration in the rat.
Topics: Animals; Anticonvulsants; Conditioning, Operant; Depression, Chemical; Food; gamma-Aminobutyric Acid; Injections, Intravenous; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Reinforcement, Psychology; Self Administration; Synaptic Transmission; Vigabatrin | 2002 |
Mechanisms of nicotine actions on dorsal raphe serotoninergic neurons.
Topics: Animals; Bicuculline; Chromatography, High Pressure Liquid; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mesencephalon; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists | 2002 |
A neurosteroid anesthetic, alphaxalone, inhibits nicotinic acetylcholine receptors in cultured bovine adrenal chromaffin cells.
Topics: Anesthetics; Animals; Calcium Channel Blockers; Cattle; Cells, Cultured; Chromaffin Cells; gamma-Aminobutyric Acid; Nicotine; Patch-Clamp Techniques; Perfusion; Picrotoxin; Pregnanediones; Receptors, GABA-A; Receptors, Nicotinic | 2002 |
Neuropathy-specific analgesic action of intrathecal nicotinic agonists and its spinal GABA-mediated mechanism.
Topics: Analgesics; Animals; Bridged Bicyclo Compounds, Heterocyclic; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Spinal; Mice; Nicotine; Nicotinic Agonists; Pyridines; Sciatic Nerve; Sciatica; Spinal Cord | 2002 |
Nicotinic receptors mediate increased GABA release in brain through a tetrodotoxin-insensitive mechanism during prolonged exposure to nicotine.
Topics: Animals; Brain; Chick Embryo; gamma-Aminobutyric Acid; In Vitro Techniques; Nicotine; Receptors, Nicotinic; Synaptic Transmission; Tetrodotoxin | 2002 |
Cholinergic modulation of purinergic and GABAergic co-transmission at in vitro hypothalamic synapses.
Topics: Adenosine Triphosphate; Animals; Chick Embryo; Cholinergic Agents; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hypothalamus; Membrane Potentials; Muscarine; Muscarinic Agonists; Nicotine; Nicotinic Agonists; Parasympathetic Nervous System; Patch-Clamp Techniques; Receptors, Muscarinic; Receptors, Purinergic; Synapses; Synaptic Transmission | 2002 |
Cholinergic modulation of nucleus accumbens medium spiny neurons.
Topics: Acetylcholine; Action Potentials; Animals; Cholinergic Agonists; Dopamine Antagonists; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Interneurons; Male; Neural Inhibition; Neural Pathways; Nicotine; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Synaptic Transmission | 2002 |
Modulation of inhibitory synaptic activity by a non-alpha4beta2, non-alpha7 subtype of nicotinic receptors in the substantia gelatinosa of adult rat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Alkaloids; Animals; Azocines; Choline; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glycine; Neural Inhibition; Nicotine; Nicotinic Agonists; Nootropic Agents; Patch-Clamp Techniques; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Substantia Gelatinosa; Synaptic Transmission | 2003 |
Opioid receptor activation attenuates nicotinic enhancement of spontaneous GABA release in lateral spiriform nucleus of the chick.
Topics: Animals; Brain; Chick Embryo; Drug Resistance; Electric Conductivity; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; gamma-Aminobutyric Acid; In Vitro Techniques; Nicotine; Nicotinic Agonists; Potassium; Receptors, Opioid; Tetrodotoxin | 2003 |
Endogenous acetylcholine and nicotine activation enhances GABAergic and glycinergic inputs to cardiac vagal neurons.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Cholinesterase Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Heart; Neostigmine; Neurons; Nicotine; Nicotinic Agonists; Parasympathetic Nervous System; Picrotoxin; Pyridazines; Rats; Strychnine; Synaptic Transmission; Vagus Nerve | 2003 |
Antisense inhibition of neuronal nicotinic receptors in the tobacco-feeding insect, Manduca sexta.
Topics: Animals; Base Sequence; Bungarotoxins; Cells, Cultured; gamma-Aminobutyric Acid; Gene Expression; Kinetics; Manduca; Mecamylamine; Neurons; Nicotine; Nicotinic Antagonists; Oligonucleotides, Antisense; Patch-Clamp Techniques; Protein Subunits; Receptors, Nicotinic | 2003 |
Respiratory sinus arrhythmia: endogenous activation of nicotinic receptors mediates respiratory modulation of brainstem cardioinhibitory parasympathetic neurons.
Topics: Animals; Arrhythmias, Cardiac; Brain Stem; Cells, Cultured; Embryo, Mammalian; Female; gamma-Aminobutyric Acid; Glycine; Heart; Heart Rate; Neural Inhibition; Neurons; Nicotine; Parasympathetic Nervous System; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Respiration; Species Specificity; Synaptic Transmission | 2003 |
Nicotine recruits a local glutamatergic circuit to excite septohippocampal GABAergic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Acyclovir; Animals; Animals, Newborn; Atropine; Bicuculline; Bungarotoxins; Carrier Proteins; Cell Count; Choline; Chromones; Cycloleucine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Electric Conductivity; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Membrane Transport Proteins; Microscopy, Electron; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Parvalbumins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Resorcinols; Septum of Brain; Synapses; Tetrodotoxin; Tubocurarine; Valine; Vesicular Glutamate Transport Protein 2; Vesicular Transport Proteins | 2003 |
Bacterial oxidation of nicotine; formation of gamma-aminobutyric acid.
Topics: Amino Acids; gamma-Aminobutyric Acid; Nicotine; Oxidation-Reduction | 1958 |
Antagonism by gamma-aminobutyric acid to the actions of 5-hydroxytryptamine and nicotine on isolated organs.
Topics: Amino Acids; Antihypertensive Agents; gamma-Aminobutyric Acid; Nicotine; Serotonin; Serotonin Antagonists | 1958 |
[Antagonistic actions of gamma-aminobutyric acid and its derivatives against acetylcholine, 5-hydroxytryptamine, nicotine and histamine have been observed in the guinea pig ileum].
Topics: Acetylcholine; Amino Acids; Cholinergic Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Histamine; Ileum; Nicotine; Serotonin; Serotonin Antagonists | 1961 |
The GABAB receptor agonists baclofen and CGP44532 decreased nicotine self-administration in the rat.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; GABA Agonists; gamma-Aminobutyric Acid; Male; Nicotine; Organophosphonates; Phosphinic Acids; Rats; Rats, Wistar; Self Administration | 2004 |
Voltage gated P/Q and N-type calcium channels mediate the nicotinic facilitation of GABAergic and glycinergic inputs to cardiac vagal neurons.
Topics: Animals; Calcium Channels; Calcium Channels, N-Type; Calcium Channels, P-Type; Calcium Channels, Q-Type; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Nicotine; Rats; Synaptic Transmission; Vagus Nerve | 2004 |
Nicotine inhibition of pulsatile GnRH secretion is mediated by GABAA receptor system in the cultured rat embryonic olfactory placode.
Topics: Animals; Bicuculline; Ectoderm; Embryo, Mammalian; GABA Antagonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; In Vitro Techniques; Neurons; Nicotine; Nicotinic Agonists; Olfactory Pathways; Periodicity; Rats; Rats, Wistar; Receptors, GABA-A; Vomeronasal Organ | 2004 |
Weak synaptic activity induces ongoing signaling to the nucleus that is enhanced by BDNF and suppressed by low-levels of nicotine.
Topics: Activating Transcription Factor 2; Animals; Brain-Derived Neurotrophic Factor; Calcium Channels, L-Type; Cell Nucleus; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Genetic Vectors; Hippocampus; Integrases; Neuronal Plasticity; Neurons; Nicotine; Rats; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses; Synaptic Transmission; Transcription Factors; Viral Proteins | 2004 |
Long-lasting nicotinic modulation of GABAergic synaptic transmission in the rat nucleus accumbens associated with behavioural sensitization to amphetamine.
Topics: Acetylcholine; Amphetamine; Animals; Animals, Newborn; Behavior, Animal; Central Nervous System Stimulants; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mecamylamine; Membrane Potentials; Motor Activity; Neural Inhibition; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nucleus Accumbens; Patch-Clamp Techniques; Rats; Rats, Wistar; Synaptic Transmission; Time Factors | 2004 |
Nicotine differentially activates inhibitory and excitatory neurons in the dorsal spinal cord.
Topics: Action Potentials; Afferent Pathways; Analgesics; Animals; Biomarkers; Calbindins; Dendrites; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neural Inhibition; Nicotine; Nociceptors; Pain; Posterior Horn Cells; Protein Subunits; Receptors, Neurokinin-1; Receptors, Nicotinic; RNA, Messenger; S100 Calcium Binding Protein G; Synaptic Transmission | 2004 |
Repeated administration of the GABAB receptor agonist CGP44532 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine-seeking in rats.
Topics: Animals; Body Weight; Conditioning, Operant; Cues; Food; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Male; Nicotine; Nicotinic Agonists; Organophosphonates; Phosphinic Acids; Rats; Rats, Wistar; Reinforcement, Psychology; Self Administration; Tobacco Use Disorder | 2005 |
Prenatal nicotine exposure alters central cardiorespiratory responses to hypoxia in rats: implications for sudden infant death syndrome.
Topics: Action Potentials; Animals; Autonomic Fibers, Preganglionic; Female; gamma-Aminobutyric Acid; Glycine; Heart; Humans; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Infant; Medulla Oblongata; Nicotine; Oxygen Consumption; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Respiration; Sudden Infant Death; Vagus Nerve | 2004 |
Intermittent morphine treatment induces a long-lasting increase in cholinergic modulation of GABAergic synapses in nucleus accumbens of adult rats.
Topics: Acetylcholine; Amphetamine; Anesthetics, Local; Animals; Central Nervous System Stimulants; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mecamylamine; Membrane Potentials; Morphine; Narcotics; Neural Inhibition; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Synapses; Tetrodotoxin | 2005 |
Role of gamma-aminobutyric acid (GABA) and metabotropic glutamate receptors in nicotine reinforcement: potential pharmacotherapies for smoking cessation.
Topics: Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Mice; Nicotine; Rats; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Reinforcement Schedule; Self Administration; Smoking Cessation | 2004 |
A developmental switch in the excitability and function of the starburst network in the mammalian retina.
Topics: Acetylcholine; Aging; Animals; Electrophysiology; Embryo, Mammalian; gamma-Aminobutyric Acid; In Vitro Techniques; Nerve Net; Nicotine; Patch-Clamp Techniques; Rabbits; Retina; Synapses; Vision, Ocular | 2004 |
Drosophila mushroom body Kenyon cells generate spontaneous calcium transients mediated by PLTX-sensitive calcium channels.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Analysis of Variance; Animals; Caffeine; Calcium; Calcium Channels; Cells, Cultured; Chlorine; Cobalt; Curare; Diagnostic Imaging; Dose-Response Relationship, Radiation; Drosophila; Drug Combinations; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fura-2; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Iodine; Mushroom Bodies; Neurons; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Phenols; Picrotoxin; Pupa; Salicylates; Spider Venoms; Tetrodotoxin; Thapsigargin; Time Factors; Valine | 2005 |
Exaggeration of epileptic-like patterns by nicotine receptor activation during the GABA withdrawal syndrome.
Topics: Animals; Epilepsy; gamma-Aminobutyric Acid; Male; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic; Substance Withdrawal Syndrome | 2005 |
Nicotine inhibits pulsatile luteinizing hormone secretion in human males but not in human females, and tolerance to this nicotine effect is lost within one week of quitting smoking.
Topics: Drug Tolerance; Female; gamma-Aminobutyric Acid; Humans; Luteinizing Hormone; Male; Nicotine; Sex Characteristics; Smoking; Testosterone | 2005 |
The Ror receptor tyrosine kinase CAM-1 is required for ACR-16-mediated synaptic transmission at the C. elegans neuromuscular junction.
Topics: Acetylcholine; Analysis of Variance; Animals; Animals, Genetically Modified; Behavior, Animal; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcium; Choline; Cholinergic Antagonists; Diagnostic Imaging; Dihydro-beta-Erythroidine; Electric Stimulation; gamma-Aminobutyric Acid; Gene Expression Regulation; In Vitro Techniques; Ion Channel Gating; Levamisole; Membrane Potentials; Microscopy, Electron, Transmission; Molecular Biology; Movement; Muscles; Mutagenesis; Mutation; Neuromuscular Junction; Neurons; Nicotine; Patch-Clamp Techniques; Receptor Protein-Tyrosine Kinases; Receptor Tyrosine Kinase-like Orphan Receptors; Receptors, Nicotinic; RNA, Small Interfering; Synaptic Transmission; Synaptic Vesicles; Time Factors; Trans-Activators | 2005 |
Nicotine-induced switch in the nicotinic cholinergic mechanisms of facilitation of long-term potentiation induction.
Topics: Acetylcholinesterase; Aconitine; Animals; Animals, Newborn; Antibodies, Monoclonal; Cholinergic Fibers; Denervation; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; Immunotoxins; In Vitro Techniques; Long-Term Potentiation; N-Glycosyl Hydrolases; Neural Inhibition; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Propanolamines; Quinoxalines; Rats; Receptors, Nicotinic; Ribosome Inactivating Proteins, Type 1; Saporins; Valine | 2005 |
Indirect modulation by alpha7 nicotinic acetylcholine receptors of noradrenaline release in rat hippocampal slices: interaction with glutamate and GABA systems and effect of nicotine withdrawal.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bacterial Toxins; Biological Transport; Conotoxins; Cyanobacteria Toxins; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Marine Toxins; Microcystins; Neurons; Nicotine; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Nicotinic; Substance Withdrawal Syndrome; Tetrodotoxin; Tropanes | 2006 |
Chronic nicotine exposure during adolescence differentially influences calcium-binding proteins in rat anterior cingulate cortex.
Topics: Administration, Oral; Aging; Animals; Calcium-Binding Proteins; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Gyrus Cinguli; Immunoenzyme Techniques; Immunohistochemistry; Injections, Subcutaneous; Interneurons; Male; Microscopy, Confocal; Nicotine; Nicotinic Agonists; Parietal Lobe; Rats; Rats, Sprague-Dawley | 2005 |
Cholinergic modulation of appetite-related synapses in mouse lateral hypothalamic slice.
Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Animals, Newborn; Appetite; Cholinergic Fibers; Female; gamma-Aminobutyric Acid; Hypothalamic Area, Lateral; Hypothalamic Hormones; In Vitro Techniques; Melanins; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Neurons; Nicotine; Pituitary Hormones; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Cholinergic; Receptors, Nicotinic; Synapses; Synaptic Transmission | 2005 |
Chronic nicotine treatment increases GABAergic input to striatal neurons.
Topics: Animals; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Neostriatum; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Stimulation, Chemical | 2006 |
Iptakalim inhibits nicotinic acetylcholine receptor-mediated currents in dopamine neurons acutely dissociated from rat substantia nigra pars compacta.
Topics: Acetylcholine; Action Potentials; Animals; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Propylamines; Rats; Rats, Wistar; Receptors, Nicotinic; Substantia Nigra | 2006 |
Nicotine-induced enhancement of synaptic plasticity at CA3-CA1 synapses requires GABAergic interneurons in adult anti-NGF mice.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Excitatory Postsynaptic Potentials; Female; gamma-Aminobutyric Acid; Ganglionic Stimulants; Hippocampus; Interneurons; Long-Term Potentiation; Male; Mice; Mice, Transgenic; Nerve Growth Factor; Neuronal Plasticity; Nicotine; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Synapses; Synaptic Transmission | 2006 |
Nicotinic modulation of network and synaptic transmission in the immature hippocampus investigated with genetically modified mice.
Topics: Acetylcholine; Action Potentials; Animals; Animals, Newborn; Excitatory Postsynaptic Potentials; Female; gamma-Aminobutyric Acid; Ganglionic Stimulants; Gene Expression Regulation; Glutamates; Hippocampus; Interneurons; Male; Mice; Mice, Knockout; Nicotine; Patch-Clamp Techniques; Pyramidal Cells; Receptors, Nicotinic; Synaptic Transmission | 2006 |
Seizures and enhanced cortical GABAergic inhibition in two mouse models of human autosomal dominant nocturnal frontal lobe epilepsy.
Topics: Animals; Disease Models, Animal; Electrophysiology; Epilepsy, Frontal Lobe; gamma-Aminobutyric Acid; Humans; Kinetics; Mice; Mice, Transgenic; Nicotine; Patch-Clamp Techniques; Receptors, Nicotinic; Seizures | 2006 |
Sequential interplay of nicotinic and GABAergic signaling guides neuronal development.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cadmium; Calcium; Chick Embryo; Chlorides; gamma-Aminobutyric Acid; Ganglia, Parasympathetic; Hippocampus; K Cl- Cotransporters; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Receptors, Nicotinic; Recombinant Fusion Proteins; Signal Transduction; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Symporters; Synaptic Transmission; Transfection | 2006 |
Quantitative trait transcripts for nicotine resistance in Drosophila melanogaster.
Topics: Animals; California; Drosophila melanogaster; Drug Resistance; Female; gamma-Aminobutyric Acid; Genetic Linkage; Genetic Variation; Glutamate Decarboxylase; Isoenzymes; Longevity; Mice; Nicotine; North Carolina; Ornithine-Oxo-Acid Transaminase; Quantitative Trait Loci | 2007 |
Prenatal nicotine exposure alters glycinergic and GABAergic control of respiratory frequency in the neonatal rat brainstem-spinal cord preparation.
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain Stem; Drug Interactions; Female; gamma-Aminobutyric Acid; Glycine; Glycine Agents; In Vitro Techniques; Microinjections; Models, Biological; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Respiration; Spinal Cord; Strychnine | 2007 |
Novel stimulus-induced calcium efflux in Drosophila mushroom bodies.
Topics: Animals; Animals, Genetically Modified; Calcium; Calcium Signaling; Drosophila melanogaster; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Mushroom Bodies; Nicotine; Nicotinic Agonists; Picrotoxin; Receptors, GABA; Sodium-Calcium Exchanger | 2007 |
Action-potential-independent GABAergic tone mediated by nicotinic stimulation of immature striatal miniature synaptic transmission.
Topics: Action Potentials; Animals; Animals, Newborn; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Potassium Chloride; Rats; Rats, Wistar; Synaptic Transmission | 2007 |
Differential modulation by nicotine of substantia nigra versus ventral tegmental area dopamine neurons.
Topics: Acetylcholine; Animals; Choline; Data Interpretation, Statistical; Dopamine; Electrophysiology; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Male; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Substantia Nigra; Synapses; Ventral Tegmental Area | 2007 |
Gain modulation by nicotine in macaque v1.
Topics: Acetylcholine; Action Potentials; Animals; Contrast Sensitivity; gamma-Aminobutyric Acid; Geniculate Bodies; Interneurons; Macaca fascicularis; Male; Microscopy, Electron, Transmission; Neural Inhibition; Neurons; Nicotine; Nicotinic Agonists; Pyramidal Cells; Receptors, Nicotinic; Synapses; Synaptic Transmission; Visual Cortex; Visual Pathways; Visual Perception | 2007 |
Neuroadaptive changes in the mesocortical glutamatergic system during chronic nicotine self-administration and after extinction in rats.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Electrochemistry; Excitatory Amino Acid Agents; Extinction, Psychological; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; N-Methylaspartate; Nicotine; Nicotinic Agonists; Potassium Chloride; Prefrontal Cortex; Rats; Rats, Inbred Lew; Self Administration; Ventral Tegmental Area | 2008 |
Peripheral nerve injury alters spinal nicotinic acetylcholine receptor pharmacology.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; gamma-Aminobutyric Acid; Male; Nicotine; Pain; Peripheral Nervous System Diseases; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Spinal Cord; Spinal Nerves | 2008 |
Presynaptic type III neuregulin 1 is required for sustained enhancement of hippocampal transmission by nicotine and for axonal targeting of alpha7 nicotinic acetylcholine receptors.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Cycloheximide; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; Glutamic Acid; Hippocampus; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Neuregulins; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Organ Culture Techniques; Patch-Clamp Techniques; Presynaptic Terminals; Protein Synthesis Inhibitors; Receptors, Nicotinic; Synaptic Transmission; Time Factors; Vesicular Glutamate Transport Protein 1 | 2008 |
Chronic nicotine modifies the effects of morphine on extracellular striatal dopamine and ventral tegmental GABA.
Topics: Animals; Brain; Dihydroxyphenylalanine; Dopamine; Extracellular Fluid; gamma-Aminobutyric Acid; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Microdialysis; Morphine; Motor Activity; Narcotics; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Time | 2008 |
Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons.
Topics: Animals; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Down-Regulation; gamma-Aminobutyric Acid; Gene Expression Regulation, Enzymologic; Glutamate Decarboxylase; Hippocampus; Male; Mice; Neurons; Nicotine; Promoter Regions, Genetic; Receptors, Cholinergic; Reelin Protein; RNA, Messenger; Time Factors; Up-Regulation | 2008 |
Rats harboring S284L Chrna4 mutation show attenuation of synaptic and extrasynaptic GABAergic transmission and exhibit the nocturnal frontal lobe epilepsy phenotype.
Topics: Age Factors; Analysis of Variance; Animals; Behavior, Animal; Cerebral Cortex; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Frontal Lobe; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hot Temperature; In Vitro Techniques; Leucine; Microscopy, Immunoelectron; Motor Activity; Motor Skills; Mutation; Neurotransmitter Agents; Nicotine; Pain Measurement; Pentylenetetrazole; Phenotype; Rats; Rats, Transgenic; Receptors, Nicotinic; Serine; Synaptic Transmission | 2008 |
Localized low-level re-expression of high-affinity mesolimbic nicotinic acetylcholine receptors restores nicotine-induced locomotion but not place conditioning.
Topics: Animals; Conditioning, Psychological; Cyclic AMP Response Element-Binding Protein; Dopamine; gamma-Aminobutyric Acid; Gene Expression Regulation; Locomotion; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nicotine; Nicotinic Agonists; Phosphorylation; Presynaptic Terminals; Receptors, Nicotinic; Reward; Synaptosomes; Tobacco Use Disorder; Ventral Tegmental Area | 2009 |
Nicotine stimulates pancreatic cancer xenografts by systemic increase in stress neurotransmitters and suppression of the inhibitory neurotransmitter gamma-aminobutyric acid.
Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cyclic AMP; Epinephrine; Extracellular Signal-Regulated MAP Kinases; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neurotransmitter Agents; Nicotine; Norepinephrine; Pancreatic Neoplasms; Transplantation, Heterologous | 2009 |
Conduction block and glial injury induced in developing central white matter by glycine, GABA, noradrenalin, or nicotine, studied in isolated neonatal rat optic nerve.
Topics: Action Potentials; Animals; Animals, Newborn; Astrocytes; Cell Survival; gamma-Aminobutyric Acid; Glycine; Microscopy, Electron; Nerve Fibers, Myelinated; Neuroglia; Neurons; Nicotine; Norepinephrine; Oligodendroglia; Optic Nerve; Optic Nerve Injuries; Patch-Clamp Techniques; Rats | 2009 |
Dopamine-deprived striatal GABAergic interneurons burst and generate repetitive gigantic IPSCs in medium spiny neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adrenergic Agents; Animals; Biological Clocks; Biophysics; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agents; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Lysine; Mice; Nicotine; Nicotinic Agonists; Oxidopamine; Patch-Clamp Techniques; Spectrum Analysis; Tyrosine 3-Monooxygenase; Valine | 2009 |
Nicotinic activation of laterodorsal tegmental neurons: implications for addiction to nicotine.
Topics: Animals; Calcium; Dendrites; Female; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Intracellular Space; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Presynaptic Terminals; Receptors, Nicotinic; Synaptic Transmission; Tegmentum Mesencephali; Tobacco Use Disorder | 2009 |
Activation of nicotinic acetylcholine receptors enhances a slow calcium-dependent potassium conductance and reduces the firing of stratum oriens interneurons.
Topics: Acetylcholine; Action Potentials; Animals; Calcium; Fluorescent Dyes; Fura-2; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Hippocampus; Interneurons; Mice; Mice, Transgenic; Nerve Net; Neural Inhibition; Nicotine; Patch-Clamp Techniques; Receptors, Nicotinic; Signal Processing, Computer-Assisted; Small-Conductance Calcium-Activated Potassium Channels; Synaptic Transmission | 2009 |
Nicotine self-administration differentially modulates glutamate and GABA transmission in hypothalamic paraventricular nucleus to enhance the hypothalamic-pituitary-adrenal response to stress.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Disease Models, Animal; Electric Stimulation; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamo-Hypophyseal System; Male; Neuronal Plasticity; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Self Administration; Stress, Psychological; Synaptic Transmission; Tobacco Use Disorder | 2010 |
Stimulation of lateral hypothalamic glutamate and acetylcholine efflux by nicotine: implications for mechanisms of nicotine-induced activation of orexin neurons.
Topics: Acetylcholine; Animals; Appetite; Arousal; Drug Administration Schedule; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamic Area, Lateral; Intracellular Signaling Peptides and Proteins; Male; Microdialysis; Neural Pathways; Neurons; Neuropeptides; Nicotine; Nicotinic Agonists; Orexins; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tobacco Use Disorder; Up-Regulation | 2010 |
Effects of Z-338, a novel gastroprokinetic agent, on the actions of excitatory and inhibitory neurotransmitters on neurons in area postrema.
Topics: Adenosine Triphosphate; Animals; Area Postrema; Benzamides; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Ganglionic Stimulants; Gastrointestinal Agents; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Kainic Acid; Male; N-Methylaspartate; Neurons; Nicotine; Patch-Clamp Techniques; Rats; Rats, Wistar; Thiazoles; Vagus Nerve | 2010 |
Addictive nicotine alters local circuit inhibition during the induction of in vivo hippocampal synaptic potentiation.
Topics: Animals; Dentate Gyrus; gamma-Aminobutyric Acid; Illicit Drugs; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Neural Inhibition; Neurons; Nicotine; Perforant Pathway; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2010 |
Prenatal nicotine exposure increases GABA signaling and mucin expression in airway epithelium.
Topics: Animals; Base Sequence; Bronchi; Cells, Cultured; DNA Primers; Epithelial Cells; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Macaca mulatta; Mucins; Mucus; Neurotransmitter Agents; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, GABA-A; Respiratory Tract Diseases; Signal Transduction; Smoking; Up-Regulation | 2011 |
Drugs of abuse and stress impair LTP at inhibitory synapses in the ventral tegmental area.
Topics: Analgesics, Opioid; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; gamma-Aminobutyric Acid; Illicit Drugs; Long-Term Potentiation; Morphine; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Stress, Physiological; Synapses; Ventral Tegmental Area | 2010 |
The nicotinic acetylcholine receptor alpha5 subunit plays a key role in attention circuitry and accuracy.
Topics: Acetylcholine; Analysis of Variance; Anesthetics, Local; Animals; Attention; Choice Behavior; Cholinergic Agents; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nerve Net; Neuropsychological Tests; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Photic Stimulation; Prefrontal Cortex; Pyramidal Cells; Reaction Time; Receptors, Nicotinic; Tetrodotoxin | 2010 |
Nicotine blocks the hyperpolarization-activated current Ih and severely impairs the oscillatory behavior of oriens-lacunosum moleculare interneurons.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Analysis of Variance; Animals; Biological Clocks; Cardiovascular Agents; Colforsin; Cyclic Nucleotide-Gated Cation Channels; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Hippocampus; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; In Vitro Techniques; Interneurons; Male; Mecamylamine; Mice; Mice, Transgenic; Models, Biological; Models, Molecular; Neural Inhibition; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Potassium Channels; Pyrimidines; Somatostatin | 2010 |
[The protective effect of nicotine on dopaminergic neuron of Parkinson's disease mice].
Topics: Animals; Caudate Nucleus; Disease Models, Animal; Dopaminergic Neurons; Female; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Nicotine; Parkinson Disease; Tyrosine 3-Monooxygenase | 2007 |
Both GABA(B) receptor activation and blockade exacerbated anhedonic aspects of nicotine withdrawal in rats.
Topics: Animals; Benzoates; Depression; Drug Synergism; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Nicotine; Phosphinic Acids; Pyrimidines; Rats; Rats, Wistar; Receptors, GABA-B; Reward; Self Stimulation; Substance Withdrawal Syndrome | 2011 |
Functional nicotinic acetylcholine receptors containing α6 subunits are on GABAergic neuronal boutons adherent to ventral tegmental area dopamine neurons.
Topics: 4-Aminopyridine; Acetylcholine; Aconitine; Animals; Animals, Newborn; Bungarotoxins; Calcium; Conotoxins; Dihydro-beta-Erythroidine; Dopamine; Drug Interactions; Excitatory Amino Acid Agents; Female; GABA Agents; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Knockout; Neurons; Nicotine; Nicotinic Antagonists; Potassium Channel Blockers; Presynaptic Terminals; Protein Binding; Rats; Rats, Wistar; Receptors, Nicotinic; Synaptosomes; Ventral Tegmental Area | 2011 |
Selective α4β2 nicotinic acetylcholine receptor agonists target epigenetic mechanisms in cortical GABAergic neurons.
Topics: Analysis of Variance; Animals; Azetidines; Behavior, Animal; Benzazepines; Cerebral Cortex; Conditioning, Classical; Cues; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Epigenomics; Exploratory Behavior; Fear; Freezing Reaction, Cataleptic; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; Male; Mecamylamine; Methyl-CpG-Binding Protein 2; Mice; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Promoter Regions, Genetic; Quinoxalines; Receptors, Nicotinic; RNA, Messenger; Varenicline | 2011 |
Acetylcholine and norepinephrine mediate GABAergic but not glycinergic transmission enhancement by melittin in adult rat substantia gelatinosa neurons.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Atropine; Carbachol; Dioxanes; gamma-Aminobutyric Acid; Glycine; Indoles; Inhibitory Postsynaptic Potentials; Male; Mecamylamine; Melitten; Muscarinic Antagonists; Neurons; Nicotine; Nicotinic Antagonists; Norepinephrine; Purinergic P2X Receptor Antagonists; Pyridoxal Phosphate; Rats; Serotonin Antagonists; Substantia Gelatinosa; Synaptic Transmission; Tropisetron | 2011 |
α4β2 nicotinic acetylcholine receptors on dopaminergic neurons mediate nicotine reward and anxiety relief.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Body Temperature; Bridged Bicyclo Compounds, Heterocyclic; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Nicotine; Nicotinic Agonists; Protein Binding; Pyridines; Receptors, Nicotinic; Reward; Synaptosomes; Tritium | 2011 |
A novel NADH-dependent and FAD-containing hydroxylase is crucial for nicotine degradation by Pseudomonas putida.
Topics: Bacterial Proteins; gamma-Aminobutyric Acid; Gene Deletion; Genome, Bacterial; Mixed Function Oxygenases; Nicotine; Protein Structure, Tertiary; Pseudomonas putida; Pyridines | 2011 |
Dual effect of beta-amyloid on α7 and α4β2 nicotinic receptors controlling the release of glutamate, aspartate and GABA in rat hippocampus.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Aspartic Acid; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Immunohistochemistry; Male; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Potassium; Rats; Rats, Wistar; Receptors, Nicotinic; Time Factors; Veratridine | 2012 |
Cooperative regulation of non-small cell lung carcinoma by nicotinic and beta-adrenergic receptors: a novel target for intervention.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cyclic AMP Response Element-Binding Protein; DNA, Neoplasm; Epinephrine; Extracellular Signal-Regulated MAP Kinases; gamma-Aminobutyric Acid; Humans; Lung Neoplasms; Molecular Targeted Therapy; Nicotine; Norepinephrine; Phosphorylation; Propranolol; Protein Subunits; Receptors, Adrenergic, beta; Receptors, Nicotinic | 2012 |
Effects of chronic nicotine on the autocrine regulation of pancreatic cancer cells and pancreatic duct epithelial cells by stimulatory and inhibitory neurotransmitters.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial Cells; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Neurotransmitter Agents; Nicotine; Pancreatic Ducts; Pancreatic Neoplasms; Phosphorylation; Receptors, Nicotinic | 2012 |
Glutamatergic and GABAergic metabolism in mouse brain under chronic nicotine exposure: implications for addiction.
Topics: Acetates; Animals; Behavior, Animal; Brain; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Nicotine; Oxidation-Reduction; Signal Transduction; Substance-Related Disorders | 2012 |
Adolescent rats are resistant to adaptations in excitatory and inhibitory mechanisms that modulate mesolimbic dopamine during nicotine withdrawal.
Topics: Adaptation, Physiological; Age Factors; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Dialysis; Dopamine; Electrochemistry; gamma-Aminobutyric Acid; Glutamic Acid; Limbic System; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Statistics as Topic; Substance Withdrawal Syndrome; Ventral Tegmental Area | 2012 |
OLM interneurons differentially modulate CA3 and entorhinal inputs to hippocampal CA1 neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; In Vitro Techniques; Interneurons; Long-Term Potentiation; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Net; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Picrotoxin; Plant Lectins; Receptors, Nicotinic; RNA, Messenger; Valine; Voltage-Sensitive Dye Imaging | 2012 |
Mice expressing the ADNFLE valine 287 leucine mutation of the Β2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function.
Topics: Acetylcholine; Animals; Body Temperature; Central Nervous System Sensitization; Cerebral Cortex; Dopamine; Dystonia; gamma-Aminobutyric Acid; Gene Knock-In Techniques; Hippocampus; Male; Mice; Motor Activity; Mutation, Missense; Nicotine; Presynaptic Terminals; Radioligand Assay; Receptors, Nicotinic; Rubidium Radioisotopes; Seizures; Synaptosomes | 2013 |
β-Blockers and metastasis in non-small-cell lung cancer.
Topics: Adrenergic beta-Antagonists; Animals; Carcinoma, Non-Small-Cell Lung; gamma-Aminobutyric Acid; Humans; Lung Neoplasms; Neoplasms; Nicotine; Propranolol; Protective Agents; Pulmonary Disease, Chronic Obstructive; Stress, Psychological | 2013 |
Transcriptional regulation by nicotine in dopaminergic neurons.
Topics: Animals; Dopamine; Dopaminergic Neurons; gamma-Aminobutyric Acid; Gene Expression Regulation; Genome; Mice; Mice, Inbred C57BL; Nicotine; Stress, Physiological; Substantia Nigra; Transcriptome | 2013 |
Reciprocal regulation of inhibitory synaptic transmission by nicotinic and muscarinic receptors in rat nucleus accumbens shell.
Topics: Acetylcholine; Animals; Animals, Genetically Modified; Atropine; Carbachol; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Interneurons; Neurons; Nicotine; Nucleus Accumbens; Pilocarpine; Presynaptic Terminals; Rats; Receptors, Muscarinic; Receptors, Nicotinic; Synaptic Transmission | 2013 |
Inhibitory effects of beta-amyloid on the nicotinic receptors which stimulate glutamate release in rat hippocampus: the glial contribution.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Aspartic Acid; Azetidines; Bridged Bicyclo Compounds, Heterocyclic; Choline; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Peptide Fragments; Pyridines; Quinuclidines; Rats; Rats, Wistar; Receptors, Nicotinic | 2014 |
Prefrontal gamma-aminobutyric acid type A receptor insertion controls cue-induced relapse to nicotine seeking.
Topics: Animals; Conditioning, Operant; Cues; Drug-Seeking Behavior; Extinction, Psychological; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Male; Muscimol; Nicotine; Peptides; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glutamate; Recurrence; Self Administration; Synapses; Tobacco Use Disorder | 2014 |
Neonatal nicotine exposure increases excitatory synaptic transmission and attenuates nicotine-stimulated GABA release in the adult rat hippocampus.
Topics: Animals; Animals, Newborn; CA1 Region, Hippocampal; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Inhibitory Postsynaptic Potentials; Male; Miniature Postsynaptic Potentials; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Pyramidal Cells; Rats, Sprague-Dawley; Receptors, AMPA; Synaptic Transmission; Tissue Culture Techniques | 2015 |
Nicotine increases GABAergic input on rat dorsal raphe serotonergic neurons through alpha7 nicotinic acetylcholine receptor.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Calcium Signaling; Dorsal Raphe Nucleus; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Models, Neurological; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Serotonergic Neurons; Serotonin | 2014 |
Tonic nicotinic transmission enhances spinal GABAergic presynaptic release and the frequency of spontaneous network activity.
Topics: Animals; Chick Embryo; Chickens; gamma-Aminobutyric Acid; Immunoblotting; Nerve Net; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Receptors, Nicotinic; Spinal Cord; Synapses; Synaptic Transmission | 2016 |
Prenatal Nicotine Exposure Impairs the Proliferation of Neuronal Progenitors, Leading to Fewer Glutamatergic Neurons in the Medial Prefrontal Cortex.
Topics: Animals; Cell Cycle; Cell Movement; Cognition Disorders; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice, Inbred C57BL; Neural Stem Cells; Neurogenesis; Neurons; Nicotine; Nicotinic Agonists; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation | 2016 |
Nicotine induces self-renewal of pancreatic cancer stem cells via neurotransmitter-driven activation of sonic hedgehog signalling.
Topics: Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Cell Self Renewal; Cell Separation; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hedgehog Proteins; Humans; Neoplastic Stem Cells; Nicotine; Nicotinic Agonists; Pancreatic Neoplasms; Receptors, Nicotinic; Signal Transduction; Spheroids, Cellular; Transcription Factors; Zinc Finger Protein GLI1 | 2016 |
Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure.
Topics: Animals; Arachidonic Acids; Endocannabinoids; gamma-Aminobutyric Acid; Glycerides; Lipoprotein Lipase; Male; Nicotine; Rats; Rats, Wistar; Self Administration; Ventral Tegmental Area | 2016 |
Activity-dependent plasticity in the isolated embryonic avian brainstem following manipulations of rhythmic spontaneous neural activity.
Topics: Animals; Brain Stem; Chick Embryo; gamma-Aminobutyric Acid; Glycine; Membrane Potentials; Microelectrodes; Models, Animal; Neuronal Plasticity; Neurons; Nicotine; Nicotinic Agonists; Periodicity; Receptors, Nicotinic; Smoking; Synaptic Transmission; Time Factors; Tissue Culture Techniques | 2016 |
Nicotine enhances GABAergic inhibition of oxytocin mRNA-expressing neuron in the hypothalamic paraventricular nucleus in vitro in rats.
Topics: Action Potentials; Animals; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Male; Neurons; Nicotine; Oxytocin; Paraventricular Hypothalamic Nucleus; Pyridazines; Rats, Wistar; RNA, Messenger; Tetrodotoxin | 2017 |
Prenatal nicotine exposure induces HPA axis-hypersensitivity in offspring rats via the intrauterine programming of up-regulation of hippocampal GAD67.
Topics: Adrenocorticotropic Hormone; Animals; Birth Weight; Corticosterone; DNA (Cytosine-5-)-Methyltransferase 1; Epigenesis, Genetic; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Hypothalamo-Hypophyseal System; Nicotine; Pituitary-Adrenal System; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Wistar; Up-Regulation | 2017 |
Developmental plasticity of GABAergic neurotransmission to brainstem motoneurons.
Topics: Animals; Animals, Newborn; Brain Stem; Female; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Male; Maternal-Fetal Exchange; Motor Neurons; Neuronal Plasticity; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Receptors, GABA; Synaptic Transmission | 2018 |
Presynaptic Regulation of Tonic Inhibition by Neuromodulatory Transmitters in the Basal Amygdala.
Topics: Adrenergic alpha-1 Receptor Antagonists; Amygdala; Animals; Desoxycorticosterone; Fear; gamma-Aminobutyric Acid; Ion Channel Gating; Male; Memory; Mice, Inbred C57BL; Neural Inhibition; Neurons; Neurotransmitter Agents; Nicotine; Norepinephrine; Presynaptic Terminals; Serotonin | 2018 |
c-Fos marking of identified midbrain neurons coactive after nicotine administration in-vivo.
Topics: Animals; Autonomic Nervous System; Cocaine; Dopamine Uptake Inhibitors; Dopaminergic Neurons; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Neurons; Nicotine; Nicotinic Agonists; Proto-Oncogene Proteins c-fos; Reward; Substance Withdrawal Syndrome; Transcriptional Activation; Ventral Tegmental Area | 2018 |
Metabolic Profiling of the Hippocampus of Rats Experiencing Nicotine-Withdrawal Symptoms.
Topics: Animals; Creatine; gamma-Aminobutyric Acid; Hippocampus; Male; Metabolome; Nicotine; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 2018 |
Effect of GAD1 genotype status on auditory attention and acute nicotine administration in healthy volunteers.
Topics: Adolescent; Adult; Attention; Event-Related Potentials, P300; gamma-Aminobutyric Acid; Genotype; Glutamate Decarboxylase; Healthy Volunteers; Humans; Male; Nicotine; Polymorphism, Single Nucleotide; Young Adult | 2019 |
Minimal Circuit Model of Reward Prediction Error Computations and Effects of Nicotinic Modulations.
Topics: Acetylcholine; Anticipation, Psychological; Computer Simulation; Conditioning, Classical; Decision Making; gamma-Aminobutyric Acid; Humans; Models, Neurological; Neural Pathways; Neurons; Nicotine; Receptors, Nicotinic; Reward; Ventral Tegmental Area | 2018 |
Prolonged exposure of rats to varenicline increases anxiety and alters serotonergic system, but has no effect on memory.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Cognition; gamma-Aminobutyric Acid; Hippocampus; Male; Memory; Models, Animal; Motor Activity; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Serotonergic Neurons; Serotonin; Smoking; Smoking Cessation; Varenicline | 2019 |
Acetylcholine receptor agonist effect on seizure activity and GABAergic mechanisms involved in prolonged febrile seizure development in an animal model.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cholinergic Agonists; Disease Models, Animal; Female; GABAergic Neurons; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Hippocampus; Male; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Receptors, Nicotinic; Seizures, Febrile; Synaptic Transmission | 2019 |
The mechanism of chronic nicotine exposure and nicotine withdrawal on pain perception in an animal model.
Topics: Animals; Baclofen; Bicuculline; Disease Models, Animal; Down-Regulation; Endorphins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hyperalgesia; Male; Naloxone; Nicotine; Pain Perception; Pain Threshold; Rats; Receptors, Opioid, mu; Spinal Cord; Substance Withdrawal Syndrome; Time Factors; Up-Regulation | 2020 |
β2* nAChRs on VTA dopamine and GABA neurons separately mediate nicotine aversion and reward.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Dopamine; Dopamine Agonists; Flupenthixol; gamma-Aminobutyric Acid; Male; Mice, Inbred C57BL; Mice, Knockout; Motivation; Nicotine; Receptors, Nicotinic; Reward; Ventral Tegmental Area | 2019 |
Amino acid systems in the interpeduncular nucleus are altered in a sex-dependent manner during nicotine withdrawal.
Topics: Amino Acids; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Interpeduncular Nucleus; Male; Nicotine; Receptors, Corticotropin-Releasing Hormone; Serotonin; Substance Withdrawal Syndrome | 2022 |
A tonic nicotinic brake controls spike timing in striatal spiny projection neurons.
Topics: Animals; Cholinergic Agents; Corpus Striatum; gamma-Aminobutyric Acid; Interneurons; Mice; Neurons; Nicotine | 2022 |
An inhibitory brainstem input to dopamine neurons encodes nicotine aversion.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Dopamine; Dopaminergic Neurons; gamma-Aminobutyric Acid; Mice; Nicotine; Receptors, Nicotinic; Ventral Tegmental Area | 2022 |
NMDA Receptor Activation and Ca
Topics: Animals; Calcium; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Nicotine; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Retina | 2023 |