nicotine has been researched along with diphenhydramine in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (40.00) | 18.7374 |
| 1990's | 1 (2.86) | 18.2507 |
| 2000's | 14 (40.00) | 29.6817 |
| 2010's | 6 (17.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Keserü, GM | 1 |
| Caron, G; Ermondi, G | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Jia, L; Sun, H | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Hayward, JN; Pavasuthipaisit, K | 1 |
| Hasl, G; Heim, F; Mitznegg, P; Pauly, H; Schubert, E; Sprügel, W | 1 |
| Demling, L; Domschke, S; Domschke, W; Heim, F; Mitznegg, P; Schubert, E; Schwemmle, K; Strunz, U | 1 |
| Izumi, H; Karita, K | 1 |
| Harmon, RE; Kennedy, J; Nanry, KP; Sewell, RG; Stiger, TR | 1 |
| Lederis, K; Medaković, M | 1 |
| Clemente, E; de Paul Lynch, V | 1 |
| Slivko, SF | 1 |
| Higgins, TN; Taylor, JD | 1 |
| Nabata, H; Saito, H; Takagi, K | 1 |
| Bhargava, LP; Dandiya, PC | 1 |
| Bruzzese, T; Casadio, S; Coppi, G; Pala, G; Turba, C | 1 |
| Primor, N | 1 |
| Kusunoki, M; Tanaka, C; Taniyama, K | 1 |
| Pragst, F; Sporkert, F | 1 |
| Fukada, A; Inui, K; Saito, H | 1 |
| MANNAIONI, PF | 1 |
| Chan, SW; Li, P; Lin, G; Rudd, JA | 1 |
| André, P; Chapy, H; Cisternino, S; Debray, M; Scherrmann, JM; Smirnova, M | 1 |
| Lardi, C; Pollak, S; Thierauf, A; Vogt, S | 1 |
| Kamei, H; Kawami, M; Nagahiro, M; Takano, M; Yumoto, R | 1 |
35 other study(ies) available for nicotine and diphenhydramine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Vasopressin released by nicotine in the monkey.
Topics: Animals; Arginine Vasopressin; Atropine; Behavior, Animal; Diphenhydramine; Electroencephalography; Eye Movements; Female; Haplorhini; Macaca mulatta; Motor Activity; Nicotine; Osmolar Concentration; Promethazine; Vasopressins | 1976 |
Immediate X-radiation induced contractions of the isolated guinea pig terminal ileum: the localization of the effect by drugs.
Topics: Acetylcholine; Animals; Atropine; Diphenhydramine; Female; Guinea Pigs; Hexamethonium Compounds; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nicotine; Tetrodotoxin; Time Factors; Verapamil; X-Rays | 1977 |
[Mode of action of bisacodyl (dulcolax) on isolated muscles of human colon (author's transl)].
Topics: Acetylcholine; Bisacodyl; Colon; Cresols; Diphenhydramine; Drug Antagonism; Histamine; Humans; Muscle Contraction; Muscle Tonus; Nicotine; Tetrodotoxin; Verapamil | 1975 |
Axon reflex flare evoked by nicotine in human skin.
Topics: Adult; Axons; Capsaicin; Diphenhydramine; Female; Humans; Injections, Intradermal; Lidocaine; Male; Middle Aged; Nerve Fibers; Nicotine; Receptors, Histamine; Reflex; Regional Blood Flow; Skin; Vasodilation | 1992 |
Supra-additive toxic interaction of nicotine with antihistamines, and enhancement by the proconvulsant pentylenetetrazole.
Topics: Animals; Diphenhydramine; Drug Synergism; Female; Histamine H1 Antagonists; Nicotine; Pentylenetetrazole; Rats; Rats, Inbred Strains; Tripelennamine | 1985 |
Pharmacological observations on the hypotensive action of extracts of teleost fish Urophyses (urotensin I) in the rat.
Topics: Acetylcholine; Angiotensin II; Animals; Atropine; Blood Pressure; Bradykinin; Diphenhydramine; Epinephrine; Female; Fishes; Heart Rate; Hexamethonium Compounds; Hypotension; Injections, Intramuscular; Injections, Intravenous; Injections, Subcutaneous; Male; Mecamylamine; Nicotine; Norepinephrine; Peptides; Perfusion; Phenoxybenzamine; Propranolol; Rats; Time Factors; Tissue Extracts | 1974 |
In vitro action of mescaline. Possible mode of action.
Topics: Anesthetics, Local; Animals; Diphenhydramine; Drug Synergism; Female; Ganglionic Blockers; Guinea Pigs; Heart Atria; Male; Mescaline; Muscle, Smooth; Nicotine; Rats; Receptors, Drug; Serotonin Antagonists; Sympatholytics; Uterus | 1968 |
[The effect of cholinomimetics, biogenic amines and their antagonists on the local anesthetic effect].
Topics: Anesthesia, Local; Animals; Cocaine; Cornea; Diphenhydramine; Diphenylacetic Acids; Epinephrine; Guinea Pigs; Histamine; Nicotine; Pilocarpine; Promethazine; Sensory Receptor Cells; Serotonin; Sympatholytics; Sympathomimetics; Tetracaine | 1967 |
Optimization of extraction and separation of narcotics from urine.
Topics: Chromatography, Gas; Chromatography, Thin Layer; Cocaine; Codeine; Diphenhydramine; Evaluation Studies as Topic; Glucosidases; Humans; Indicators and Reagents; Meperidine; Methadone; Methaqualone; Methods; Morphine; Nalorphine; Narcotics; Nicotine; Pentazocine; Phenmetrazine; Time Factors | 1974 |
Pharmacological studies of Panax ginseng root: estimation of pharmacological actions of Panax ginseng root.
Topics: Acetylcholine; Animals; Atropine; Behavior, Animal; Blood Pressure; Central Nervous System; Diphenhydramine; Epinephrine; Guinea Pigs; Heart Rate; Histamine; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Nicotine; Panax; Phentolamine; Plant Extracts; Plants, Medicinal; Propranolol; Rats; Respiration; Saponins; Serotonin | 1972 |
The antiparkinsonian activity of monoamine oxidase inhibitors and other agents in rats and mice.
Topics: Animals; Dextroamphetamine; Diphenhydramine; Imipramine; Iproniazid; Isocarboxazid; Mice; Monoamine Oxidase Inhibitors; Nialamide; Nicotine; Nortropanes; Pargyline; Parkinson Disease; Parkinson Disease, Secondary; Perphenazine; Phenelzine; Physostigmine; Rats; Scopolamine; Sulfonic Acids; Tolazoline; Tremor; Tremorine; Trihexyphenidyl; Tryptamines | 1968 |
Hypoglycemic activity and pharmacological picture of 4-(1-naphthyl)butylamine derivatives.
Topics: Acetylcholine; Animals; Atropine; Behavior, Animal; Blood Glucose; Blood Pressure; Butylamines; Chemistry, Organic; Chlorpromazine; Chlorpropamide; Cocaine; Cough; Diphenhydramine; Diuresis; Edema; Guinea Pigs; Hexamethonium Compounds; Histamine; Hydrochlorothiazide; Morphine; Naphthalenes; Nicotine; Organic Chemistry Phenomena; Phenylbutazone; Rats; Serotonin; Spasm | 1966 |
Pardaxin produces postjunctional muscle contraction in guinea-pig intestinal smooth muscle.
Topics: Acetylcholine; Animals; Diphenhydramine; Drug Interactions; Electric Stimulation; Fish Venoms; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Morphine; Muscle Contraction; Muscle, Smooth; Nicotine; Physostigmine; Serotonin; Spider Venoms; Substance P | 1984 |
Inhibitory histamine H2-receptor in the guinea-pig urinary bladder.
Topics: Acetylcholine; Animals; Calcium; Choline; Cimetidine; Diphenhydramine; Electric Stimulation; Female; Guinea Pigs; Histamine; Imidazoles; Impromidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Pyrilamine; Receptors, Histamine; Receptors, Histamine H2; Scopolamine; Tetrodotoxin; Urinary Bladder | 1984 |
Use of headspace solid-phase microextraction (HS-SPME) in hair analysis for organic compounds.
Topics: Antidepressive Agents, Tricyclic; Cannabinoids; Chlormethiazole; Diphenhydramine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Lidocaine; Methadone; Nicotine; Poisoning; Sensitivity and Specificity; Solvents; Substance Abuse Detection; Tramadol | 2000 |
Transport mechanisms of nicotine across the human intestinal epithelial cell line Caco-2.
Topics: Biological Transport; Caco-2 Cells; Chlorpheniramine; Cyclosporine; Digoxin; Diphenhydramine; Humans; Intestinal Mucosa; Kinetics; Nicotine; Recombinant Proteins; Transfection; Tritium | 2002 |
Interaction between histamine and dichloroisoproterenol, hexamethonium, pempidine, and diphenhydramine, in normal and reserpine-treated heart preparations.
Topics: Diphenhydramine; Ganglionic Blockers; Guinea Pigs; Heart; Hexamethonium; Hexamethonium Compounds; Histamine; Isoproterenol; Myocardium; Nicotine; Pempidine; Piperidines; Reserpine; Sympatholytics | 1960 |
Action of anti-tussive drugs on the emetic reflex of Suncus murinus (house musk shrew).
Topics: Analysis of Variance; Animals; Antiemetics; Antitussive Agents; Baclofen; Cevanes; Codeine; Copper Sulfate; Diphenhydramine; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Motion Sickness; Nicotine; Reflex; Scopolamine; Shrews; Vomiting | 2007 |
Coexistence of passive and proton antiporter-mediated processes in nicotine transport at the mouse blood-brain barrier.
Topics: Animals; Antiporters; ATP-Binding Cassette Transporters; Binding, Competitive; Biological Transport; Blood-Brain Barrier; Diffusion; Diphenhydramine; Hydrogen-Ion Concentration; Kinetics; Male; Mice; Mice, Knockout; Models, Biological; Nicotine; Nonlinear Dynamics; Organic Cation Transport Proteins; Perfusion; Tramadol | 2013 |
Complex suicide with homemade nicotine patches.
Topics: Chromatography, Liquid; Diphenhydramine; Forensic Toxicology; Ganglionic Stimulants; Gas Chromatography-Mass Spectrometry; Humans; Hypnotics and Sedatives; Male; Middle Aged; Nicotine; Suicide; Tobacco Use Cessation Devices | 2014 |
Nicotine transport in lung and non-lung epithelial cells.
Topics: Biological Transport; Carnitine; Cells, Cultured; Diphenhydramine; Drug Interactions; Epithelial Cells; Humans; Hydrogen-Ion Concentration; Lung; Nicotine; Pyrilamine; Temperature; Tetraethylammonium; Time Factors; Tritium; Valinomycin | 2017 |