nicotine has been researched along with dinoprostone in 80 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (16.25) | 18.7374 |
| 1990's | 26 (32.50) | 18.2507 |
| 2000's | 20 (25.00) | 29.6817 |
| 2010's | 20 (25.00) | 24.3611 |
| 2020's | 1 (1.25) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Hata, F; Takeuchi, T; Yagasaki, O | 1 |
| Hori, K; Ito, S; Miyakawa, A; Mochizuki-Oda, N; Negishi, M; Ozaki, K | 1 |
| Cho, CH; Teh, GW | 1 |
| Endoh, K; Kauffman, GL; Leung, FW | 1 |
| Hui, SC; Ogle, CW | 1 |
| Hayaishi, O; Hayashi, H; Ito, S; Negishi, M; Tanaka, T; Yokohama, H | 1 |
| Hayaishi, O; Ito, S; Negishi, M | 1 |
| Funk, CD; Karaplis, AC; Powell, WS | 1 |
| Okuda, M; Shimizu, M; Takeuchi, T; Yagasaki, O | 1 |
| Takeuchi, T; Yagasaki, O | 1 |
| Bull, HA; Machin, SJ; Pittilo, RM; Woolf, N | 1 |
| Okpako, DT; Taiwo, YO | 1 |
| Mänistö, J; Puustinen, T; Uotila, P | 1 |
| Gromov, AI | 1 |
| Wennmalm, A | 1 |
| Watt, AJ | 1 |
| Bing, RJ; Metz, MZ; Ohashi, M; Sato, M | 1 |
| Dusting, GJ; May, DE; Nolan, PN; Staszewska-Barczak, J | 1 |
| Alanko, J; Mucha, I; Parviainen, M; Riutta, A; Saareks, V; Vapaatalo, H | 1 |
| Keuskamp, ZJ; Madretsma, GS; Van Dijk, JP; Zijlstra, FJ | 1 |
| Brigham, M; Correa, A; Slomiany, A; Slomiany, BL; Wang, SL; Wu-Wang, CY | 2 |
| Alanko, J; Mucha, I; Riutta, A; Saareks, V; Vapaatalo, H | 1 |
| Bukhave, K; Chen, D; Farnebo, LO; Graffner, H; Lindell, G; Nexø, E; Rask Madsen, J | 1 |
| Avunduk, C; Eastwood, GL; Quimby, GF | 1 |
| Dunning, DG; Dyer, JK; Johnson, GK; Maze, CA; Payne, JB; Reinhardt, RA | 1 |
| Egger, C; Fischer-Colbrie, R; Laslop, A; Wolkersdorfer, M | 1 |
| Bukhave, K; Graffner, H; Lilja, I; Lindell, G; Madsen, JR | 1 |
| Warashina, A | 1 |
| Johnson, GK; Organ, CC | 1 |
| Cho, CH; Chow, JY; Ma, L; Zhu, M | 1 |
| Bernzweig, E; Dyer, JK; Patil, KD; Payne, JB; Reinhardt, RA | 1 |
| Mucha, I; Riutta, A; Saareks, V; Sievi, E; Vapaatalo, H | 1 |
| Brouwer, AJ; Feyerabend, C; Hop, WC; Meijssen, MA; van Bergeijk, JD; van Dijk, AP; Wilson, JH; Zijlstra, FJ | 1 |
| Ito, K; Murai, S; Shimada, K; Sugano, N | 1 |
| Fallone, CA; MacNaughton, WK; Morris, GP; Pringle, GC | 1 |
| Hemontolor, ME; Olenick, M; Rama Sastry, BV | 1 |
| Cohen, P; Eliakim, R; Fich, A; Karmeli, F; Rachmilewitz, D | 1 |
| Cohen, P; Eliakim, R; Heyman, SN; Karmeli, F; Rachmilewitz, D | 1 |
| Du, C; Role, LW | 1 |
| Ikeda, K; Kobayashi, S; Miyata, K; Suzuki, M; Yamada, T | 1 |
| Cho, CH; Koo, MW; Liu, ES; Shin, VY; Wong, D | 1 |
| Cho, CH; Koo, MW; Liu, ES; Luo, JC; Shin, VY; So, WH; Wu, WK; Ye, YN | 1 |
| Chen, YC; Lee, TJ; Lin, HY; Shen, SC; Tsai, SH | 1 |
| Chen, L; Kroening, PR; Lau, JS; Tamada, K; Vassallo, R | 1 |
| Katono, T; Maeno, M; Motohashi, M; Sato, S; Shoji, M; Suzuki, N; Tanabe, N; Tanaka, H | 1 |
| Balatsouka, D; Berglundh, T; Gotfredsen, K; Lindh, CH; Sørensen, L | 1 |
| Hamano, R; Iwagaki, H; Nishibori, M; Takahashi, HK; Tanaka, N; Yoshino, T | 1 |
| Katono, T; Kawato, T; Maeno, M; Motohashi, M; Oka, H; Suzuki, N; Tanabe, N; Yamanaka, K | 1 |
| Hamano, R; Iwagaki, H; Kanke, T; Liu, K; Nishibori, M; Sadamori, H; Takahashi, HK; Tanaka, N; Yagi, T; Yoshino, T | 1 |
| Katono, T; Maeno, M; Mitsui, N; Morozumi, A; Shoji, M; Suzuki, N; Takeichi, O; Tanabe, N | 1 |
| Cho, CH; Lam, EK; Tai, EK; Wong, HP; Wu, WK; Yu, L | 1 |
| Kita, H; Kroening, PR; Parambil, J; Vassallo, R | 1 |
| Cho, CH; Jin, HC; Leung, WK; Ng, EK; Shin, VY; Sung, JJ; Yu, J | 1 |
| Katono, T; Kawato, T; Kitami, S; Maeno, M; Morita, T; Motohashi, M; Suzuki, N; Tanabe, N; Tanaka, H | 1 |
| Basselin, M; Chang, L; Chen, M; Greenstein, D; Nguyen, HN; Rapoport, SI | 1 |
| Nakao, S; Ogata, Y; Sugiya, H | 1 |
| Jeong, GS; Jeong, SN; Kim, EC; Kim, YC; Lee, SH | 1 |
| Kou, YR; Lee, CW; Lee, IT; Lin, CC; Yang, CM; Yang, YL | 1 |
| Liu, K; Liu, R; Mori, S; Nishibori, M; Takahashi, HK; Wake, H; Yoshino, T; Zhang, J | 1 |
| Qiao, ZD; Tang, MP; Wang, LY; Wang, ZX; Xu, WJ; Yao, CJ; Zhou, Y | 1 |
| Chung, HT; Jeong, GS; Kim, EC; Kim, YS; Lee, SK; Oh, HW; Pae, HO; Pi, SH | 1 |
| Bedison, R; Byer, B; Coelho, P; Di, YP; Kang, J; Lee, J; Ngo, K; Sowa, G; Studer, R; Vo, N; Wang, D; Witt, W | 1 |
| Bae, WJ; Chung, JH; Herr, Y; Kang, KL; Kim, EC; Kim, YS; Shin, SI | 1 |
| Auh, QS; Bae, SJ; Baek, HS; Chun, YH; Kang, KL; Kim, EC; Kim, YS; Park, BH; Park, GJ | 1 |
| Amanzadeh, A; Aslani, HR; Bidgoli, SA; Esfahani, M; Esfandiary, M; Ghahremani, MH; Habibzadeh, N; Salimi, M; Sedaghati, B | 1 |
| Arancibia, R; Cáceres, M; Couve, E; Martínez, C; Martínez, J; Romero, A; Silva, D; Smith, PC | 1 |
| Bae, WJ; Cho, YA; Heo, SH; Jue, SS; Kim, EC; Kwon, IK; Lee, SC; Shin, SI | 1 |
| Ali, SS; Ayuob, NN; Hamed, EA; Shaker Ali, A; Suliman, MI | 1 |
| Jacquier-Sarlin, MR; Meresse, P; Pelissier-Rota, MA; Pelosi, L | 1 |
| Bae, WJ; Hong, JY; Kim, EC; Kim, GT; Yi, JK | 1 |
| Costa-Rodrigues, J; Fernandes, MH; Rocha, I | 1 |
| Bizzarri, M; Catizone, A; Coluccia, P; Cucina, A; de Toma, G; Dinicola, S; Fabrizi, G; Masiello, MG; Proietti, S; Ricci, G | 1 |
| al'Absi, M; Benowitz, NL; Carmella, SG; Cinciripini, PM; Donny, EC; Drobes, DJ; Hatsukami, DK; Hecht, SS; Heskin, AK; Ikuemonisan, J; Jensen, J; Koopmeiners, J; Leischow, S; Luo, X; Robinson, JD; Strasser, AA; Tang, MK; Vandrey, R | 1 |
| Changlu, L; Liu, J; Peng, W; Sriram, S | 1 |
1 review(s) available for nicotine and dinoprostone
| Article | Year |
|---|---|
Interaction of nicotine and prostaglandins in the cardiovascular system.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cardiovascular Physiological Phenomena; Cardiovascular System; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Female; Humans; Hyperemia; Indomethacin; Kidney; Microsomes; Muscle, Smooth, Vascular; Nicotine; Pregnancy; Prostaglandins; Prostaglandins E; Smoking; Umbilical Arteries | 1982 |
2 trial(s) available for nicotine and dinoprostone
| Article | Year |
|---|---|
Transdermal nicotine inhibits interleukin 2 synthesis by mononuclear cells derived from healthy volunteers.
Topics: Administration, Cutaneous; Adult; Anti-Inflammatory Agents; Cotinine; Dinoprostone; Female; Humans; Interferon-gamma; Interleukin-10; Interleukin-13; Interleukin-2; Interleukin-4; Leukocytes, Mononuclear; Leukotriene B4; Male; Middle Aged; Nicotine; Nicotinic Agonists; Phytohemagglutinins; Smoking Cessation; Thromboxane B2; Tumor Necrosis Factor-alpha | 1998 |
Effects of immediate versus gradual nicotine reduction in cigarettes on biomarkers of biological effects.
Topics: Adult; Bayes Theorem; Biomarkers; C-Reactive Protein; Cigarette Smoking; Dinoprost; Dinoprostone; Erythrocyte Count; Erythrocyte Indices; Female; Humans; Inflammation; Leukocyte Count; Male; Middle Aged; Nicotine; Nicotinic Agonists; Oxidative Stress; Platelet Count; Smoking Reduction; Tobacco Products | 2019 |
77 other study(ies) available for nicotine and dinoprostone
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Role of cyclic AMP in prostaglandin-induced modulation of acetylcholine release from the myenteric plexus of guinea pig ileum.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Colforsin; Cyclic AMP; Dinoprostone; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth; Myenteric Plexus; Nicotine; Prostaglandins | 1992 |
Characterization of prostaglandin E2-induced Ca2+ mobilization in single bovine adrenal chromaffin cells by digital image microscopy.
Topics: Adrenal Medulla; Animals; Calcium; Calcium Channel Blockers; Cattle; Chromaffin System; Dinoprostone; Fluorescent Dyes; Fura-2; Hexamethonium; Hexamethonium Compounds; Histamine; Kinetics; Lanthanum; Microscopy, Fluorescence; Nicardipine; Nicotine; Nicotinic Antagonists; Pertussis Toxin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
The inhibitory action of zinc sulphate on the contractile activity of guinea-pig ileum.
Topics: Acetylcholine; Animals; Dinoprostone; Electric Stimulation; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nicotine; Serotonin; Sulfates; Zinc; Zinc Sulfate | 1991 |
Mechanism of aggravation of mucosal injury by intravenous nicotine in rat stomach.
Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Animals; Dinoprostone; Gastric Mucosa; Hydrogen; Hyperemia; Injections, Intravenous; Male; Nicotine; Rats; Rats, Inbred Strains; Sodium Chloride | 1991 |
Chronic nicotine treatment enhances the depressor responses to arachidonic acid in the rat.
Topics: Administration, Oral; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Indomethacin; Injections, Intravenous; Male; Nicotine; Nitroprusside; Rats; Rats, Inbred Strains | 1991 |
Synergistic effect of prostaglandin E2 and ouabain on catecholamine release from cultured bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Calcium; Carrier Proteins; Catecholamines; Cattle; Cells, Cultured; Dinoprostone; Drug Synergism; Kinetics; Nicotine; Ouabain; Receptors, Prostaglandin; Sodium; Sodium-Hydrogen Exchangers | 1990 |
Prostaglandin E receptors in bovine adrenal medulla are coupled to adenylate cyclase via Gi and to phosphoinositide metabolism in a pertussis toxin-insensitive manner.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenal Medulla; Animals; Bucladesine; Catecholamines; Cattle; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; GTP-Binding Proteins; Nicotine; Pertussis Toxin; Phosphatidylinositols; Receptors, Prostaglandin; Receptors, Prostaglandin E; Type C Phospholipases; Virulence Factors, Bordetella | 1989 |
Binding of prostaglandin E2 to cultured bovine adrenal chromaffin cells and its effect on catecholamine secretion.
Topics: Animals; Cattle; Cells, Cultured; Chromaffin Granules; Chromaffin System; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; GTP-Binding Proteins; Nicotine; Norepinephrine; Phosphatidylinositols; Prostaglandins | 1989 |
Contribution of external Ca2+ to the modulation by prostaglandin E2 of the release of acetylcholine from the myenteric plexus of guinea pig ileum.
Topics: Acetylcholine; Animals; Calcium; Dinoprostone; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Male; Myenteric Plexus; Nicotine; Potassium | 1989 |
Modulation of acetylcholine release from guinea-pig Ileum myenteric plexus by arachidonic acid cascade inhibitors.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Male; Myenteric Plexus; Nicotine; Phospholipases A; Prostaglandins E; Quinacrine | 1987 |
The effect of nicotine on human endothelial cell release of prostaglandins and ultrastructure.
Topics: Calcimycin; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Epoprostenol; Humans; Microscopy, Electron; Microscopy, Electron, Scanning; Nicotine; Prostaglandins E | 1988 |
Cyclo-oxygenase inhibitors antagonize indirectly evoked contractions of the guinea-pig isolated ileum by inhibiting acetylcholine release.
Topics: Acetylcholine; Animals; Cyclooxygenase Inhibitors; Dinoprostone; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Ketoprofen; Male; Meclofenamic Acid; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Nicotine; Prostaglandins E; Synaptic Membranes | 1984 |
Nicotine has no effect on the metabolism of exogenous arachidonic acid or prostaglandin E2 in isolated perfused rat and hamster lungs.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cricetinae; Dinoprostone; Female; In Vitro Techniques; Lipoxygenase; Lung; Mesocricetus; Nicotine; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rats; Rats, Inbred Strains | 1984 |
[Effect of prostaglandins on the sensitivity of cerebral cortical neurons in rabbits to cholinoreceptor agonists].
Topics: Action Potentials; Animals; Arecoline; Cerebral Cortex; Dinoprost; Dinoprostone; Drug Interactions; Neurons; Nicotine; Prostaglandins E; Prostaglandins F; Rabbits; Receptors, Cholinergic | 1983 |
Direct and indirect effects of adenosine 5'-triphosphate on guinea-pig ileum.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Dinoprostone; Drug Interactions; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nicotine; Prostaglandins E; Scopolamine; Serotonin | 1982 |
Inhibitory effect of a calcium antagonist (diltiazem) on aortic and coronary contractions in rabbits.
Topics: Animals; Aorta; Arteries; Benzazepines; Calcium Channel Blockers; Coronary Vessels; Depression, Chemical; Diltiazem; Dinoprost; Dinoprostone; Muscle Contraction; Muscle, Smooth, Vascular; Nicotine; Prostaglandins E; Prostaglandins F; Rabbits; Serotonin | 1982 |
Effects of prostacyclin on cardiovascular reflexes from the ventricular epicardium of the dog: comparison with the effects of prostaglandin E2.
Topics: Animals; Bradykinin; Dinoprostone; Dogs; Epoprostenol; Female; Heart; Hemodynamics; Male; Myocardium; Nicotine; Prostaglandins; Prostaglandins E | 1981 |
Smoking cessation and nicotine substitution modulate eicosanoid synthesis ex vivo in man.
Topics: Adult; Dinoprostone; Eicosanoids; Female; Humans; Leukotrienes; Male; Middle Aged; Nicotine; Smoking Cessation; Thromboxanes; Time Factors | 1995 |
Nicotine inhibits cytokine synthesis by mouse colonic mucosa.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Colitis, Ulcerative; Colon; Cytokines; Dinoprostone; Female; Interleukin-1; Intestinal Mucosa; Leukotriene B4; Leukotriene C4; Mice; Mice, Inbred BALB C; Nicotine; Platelet Activating Factor; Prostaglandins; Thromboxane B2; Tumor Necrosis Factor-alpha | 1995 |
Effects of benzo(a)pyrene and nicotine on prostaglandin synthesis in buccal pouch and submandibular glands of the Syrian hamster.
Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Animals; Benzo(a)pyrene; Cheek; Cricetinae; Dinoprost; Dinoprostone; Drug Synergism; Male; Mesocricetus; Mouth Mucosa; Nicotine; Prostaglandins; Radioimmunoassay; Submandibular Gland | 1993 |
Nicotine and cotinine modulate eicosanoid production in human leukocytes and platelet rich plasma.
Topics: Blood Platelets; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Cotinine; Dinoprostone; Dose-Response Relationship, Drug; Humans; Leukotriene B4; Neutrophils; Nicotine; Radioimmunoassay; Smoking; Thromboxane B2 | 1993 |
Expression of prostaglandin E2 receptor in hamster buccal pouch: effect of benzo (a) pyrene and nicotine.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Topical; Animals; Benzo(a)pyrene; Binding, Competitive; Body Weight; Cheek; Cricetinae; Dinoprostone; Epoprostenol; Male; Mesocricetus; Mouth Mucosa; Nicotine; Organ Size; Prostaglandin D2; Receptors, Prostaglandin E | 1993 |
Acute effects of smoking during modified sham feeding in duodenal ulcer patients. An analysis of nicotine, acid secretion, gastrin, catecholamines, epidermal growth factor, prostaglandin E2, and bile acids.
Topics: Bile Acids and Salts; Catecholamines; Dinoprostone; Duodenal Ulcer; Eating; Epidermal Growth Factor; Female; Gastric Acid; Gastric Juice; Gastrins; Humans; Male; Middle Aged; Nicotine; Saliva; Smoking; Vagus Nerve | 1993 |
Nicotine has no effect on rat gastric mucosal prostaglandin generation in vitro.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprostone; Gastric Mucosa; In Vitro Techniques; Indomethacin; Male; Nicotine; Rats; Rats, Inbred Lew | 1993 |
Nicotine effects on PGE2 and IL-1 beta release by LPS-treated human monocytes.
Topics: Adult; Analysis of Variance; Bone Resorption; Cells, Cultured; Dinoprostone; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Female; Humans; Interleukin-1; Lipopolysaccharides; Male; Middle Aged; Monocytes; Nicotine; Nicotinic Agonists; Periodontal Diseases; Porphyromonas gingivalis; Up-Regulation | 1996 |
Nicotine and prostaglandin E induce secretogranin II levels in bovine chromaffin cells.
Topics: Animals; Calcium Channel Agonists; Cattle; Cells, Cultured; Chromaffin Cells; Chromogranins; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dinoprostone; Nicotine; Protein Biosynthesis; Protein Kinase C; Proteins; Second Messenger Systems; Signal Transduction | 1996 |
Acute effects of high-dose intragastric nicotine on mucosal defense mechanisms: an analysis of nicotine, prostaglandin E2, phospholipase A2, and phospholipids.
Topics: Adult; Dinoprostone; Dose-Response Relationship, Drug; Female; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Nicotine; Nicotinic Agonists; Phospholipases A; Phospholipases A2; Phospholipids; Smoking; Stomach; Tablets | 1997 |
Potentiation by indomethacin of receptor-mediated catecholamine secretion in rat adrenal medulla.
Topics: Adrenal Medulla; Animals; Arachidonic Acid; Bradykinin; Calcium; Catecholamines; Chromaffin Granules; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Fluorescent Dyes; Histamine; Ibuprofen; Indoles; Indomethacin; Male; Muscarine; Muscarinic Agonists; Nicotine; Oxytocics; Potassium; Rats; Rats, Wistar | 1997 |
Prostaglandin E2 and interleukin-1 concentrations in nicotine-exposed oral keratinocyte cultures.
Topics: Adult; Analysis of Variance; Cell Count; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Gingiva; Humans; Inflammation Mediators; Interleukin-1; Keratinocytes; Male; Nicotiana; Nicotine; Plants, Toxic; Time Factors | 1997 |
The potentiating actions of cigarette smoking on ethanol-induced gastric mucosal damage in rats.
Topics: Acetic Acid; Animals; Cold Temperature; Dinoprostone; Ethanol; Gastric Mucosa; Leukotriene C4; Male; Nicotine; Peroxidase; Rats; Rats, Sprague-Dawley; Restraint, Physical; Smoking; Stomach Ulcer; Stress, Psychological; Tobacco Smoke Pollution | 1997 |
Nicotine and smokeless tobacco effects on gingival and peripheral blood mononuclear cells.
Topics: Analysis of Variance; Cells, Cultured; Dinoprostone; Gingiva; Humans; Immunoassay; Interleukin-1; Leukocytes, Mononuclear; Middle Aged; Nicotine; Periodontitis; Plants, Toxic; Tobacco, Smokeless | 1998 |
Nicotine stereoisomers and cotinine stimulate prostaglandin E2 but inhibit thromboxane B2 and leukotriene E4 synthesis in whole blood.
Topics: Adult; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcimycin; Cotinine; Dinoprostone; Humans; In Vitro Techniques; Ionophores; Leukotriene E4; Middle Aged; Nicotine; Prostaglandin-Endoperoxide Synthases; Stereoisomerism; Thromboxane B2 | 1998 |
Nicotine inhibits the production of inflammatory mediators in U937 cells through modulation of nuclear factor-kappaB activation.
Topics: Cyclooxygenase 2; Cytokines; Dinoprostone; Gene Expression Regulation; Humans; Inflammation; Interleukin-1; Interleukin-8; Isoenzymes; Lipopolysaccharides; Membrane Proteins; NF-kappa B; Nicotine; Prostaglandin-Endoperoxide Synthases; Transcription, Genetic; U937 Cells | 1998 |
Gastric cytoprotection is secondary to increased mucosal fluid secretion: a study of six cytoprotective agents in the rat.
Topics: Animals; Anti-Ulcer Agents; Capsaicin; Cytoprotection; Cytotoxins; Dinoprostone; Ethylmaleimide; Female; Gastric Mucosa; Hydrochloric Acid; Male; Misoprostol; Nicotine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Rioprostil | 1998 |
Prostaglandin E2 in human placenta: its vascular effects and activation of prostaglandin E2 formation by nicotine and cotinine.
Topics: Adult; Cotinine; Dinoprostone; Enzyme Activation; Female; Humans; In Vitro Techniques; Nicotine; Nicotinic Agonists; Phospholipases A; Phospholipases A2; Placenta; Pregnancy; Vasoconstriction | 1999 |
Effect of chronic nicotine administration on trinitrobenzene sulphonic acid-induced colitis.
Topics: Animals; Colitis; Colon; Dinoprostone; Dose-Response Relationship, Drug; Interleukin-1; Intestinal Mucosa; Leukotriene B4; Male; Nicotine; Nitric Oxide Synthase; Peroxidase; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid | 1998 |
Dual effect of chronic nicotine administration: augmentation of jejunitis and amelioration of colitis induced by iodoacetamide in rats.
Topics: Animals; Colitis; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Enteritis; Intestinal Mucosa; Iodoacetamide; Jejunal Diseases; Male; Nicotine; Nitric Oxide Synthase; Peroxidase; Probability; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity; Statistics, Nonparametric | 2001 |
Differential modulation of nicotinic acetylcholine receptor subtypes and synaptic transmission in chick sympathetic ganglia by PGE(2).
Topics: Animals; Bungarotoxins; Cells, Cultured; Chick Embryo; Choline; Dinoprostone; Excitatory Postsynaptic Potentials; Ganglia, Sympathetic; Ion Channel Gating; Neuronal Plasticity; Neurons; Nicotine; Nicotinic Agonists; Nootropic Agents; Receptors, Nicotinic; Spinal Cord; Synaptic Transmission; Up-Regulation | 2001 |
Effects of YM905, a novel muscarinic M3-receptor antagonist, on experimental models of bowel dysfunction in vivo.
Topics: Animals; Bethanechol; Cholera Toxin; Colonic Diseases, Functional; Defecation; Diarrhea; Dinoprostone; Disease Models, Animal; Intestines; Isoquinolines; Male; Muscarinic Antagonists; Neostigmine; Nicotine; Quinuclidines; Rats; Receptor, Muscarinic M3; Receptors, Muscarinic; Serotonin; Solifenacin Succinate; Stress, Physiological; Tetrahydroisoquinolines | 2001 |
Pathogenesis of nicotine treatment and its withdrawal on stress-induced gastric ulceration in rats.
Topics: Animals; Dinoprostone; Female; Gastric Mucosa; Glutathione; Nicotine; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Stress, Physiological | 2002 |
Nicotine promotes gastric tumor growth and neovascularization by activating extracellular signal-regulated kinase and cyclooxygenase-2.
Topics: Adenocarcinoma; Animals; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Ganglionic Stimulants; Isoenzymes; MAP Kinase Kinase 1; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Nicotine; Phosphorylation; Proliferating Cell Nuclear Antigen; Prostaglandin-Endoperoxide Synthases; Signal Transduction; Stomach Neoplasms; Transplantation, Heterologous; Vascular Endothelial Growth Factor A | 2004 |
Nicotine enhancement of lipopolysaccharide/interferon-gamma-induced cytotoxicity with elevating nitric oxide production.
Topics: Animals; Cell Line; Cell Survival; Dinoprostone; Interferon-gamma; Lipopolysaccharides; Mice; Nicotine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine | 2004 |
Cigarette smoke extract suppresses human dendritic cell function leading to preferential induction of Th-2 priming.
Topics: Adjuvants, Immunologic; Cell Death; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cyclooxygenase 2; Cytokines; Dendritic Cells; Dinoprostone; Down-Regulation; Growth Inhibitors; Humans; Immunophenotyping; Immunosuppressive Agents; Interleukin-10; Interleukin-12; Lipopolysaccharides; Lymphocyte Activation; Nicotine; Receptors, Chemokine; Smoke; T-Lymphocytes; Th2 Cells; Up-Regulation | 2005 |
Nicotine and lipopolysaccharide stimulate the formation of osteoclast-like cells by increasing macrophage colony-stimulating factor and prostaglandin E2 production by osteoblasts.
Topics: Alkaline Phosphatase; Animals; Cell Line, Tumor; Cell Proliferation; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Gene Expression; Glycoproteins; Humans; Lipopolysaccharides; Macrophage Colony-Stimulating Factor; Mice; Nicotine; Osteoblasts; Osteoclasts; Osteoprotegerin; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Effect of systemic administration of nicotine on healing in osseous defects. An experimental study in rabbits. Part II.
Topics: Animals; Body Weight; Bone Density; Bone Diseases; Cotinine; Dinoprostone; Female; Ganglionic Stimulants; Infusion Pumps, Implantable; Nicotine; Nicotinic Agonists; Placebos; Rabbits; Tibia; Time Factors; Wound Healing | 2006 |
Effect of nicotine on IL-18-initiated immune response in human monocytes.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Antigens, CD; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Cytokines; Dinoprostone; Gene Expression Regulation; Humans; Interleukin-18; Macrophage Activation; Membrane Proteins; Monocytes; Nicotine; Nicotinic Agonists; Receptors, Nicotinic; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction | 2006 |
Nicotine treatment induces expression of matrix metalloproteinases in human osteoblastic Saos-2 cells.
Topics: Cell Line, Tumor; Dinoprostone; Ganglionic Stimulants; Humans; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; Matrix Metalloproteinases; Nicotine; Osteoblasts; Plasminogen Activators; Proto-Oncogene Proteins c-fos; Tissue Plasminogen Activator | 2006 |
The immunosuppressive effects of nicotine during human mixed lymphocyte reaction.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Cell Adhesion Molecules; Cell Proliferation; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2 Inhibitors; Cytokines; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Immunosuppressive Agents; Interleukin-18; Lymphocyte Culture Test, Mixed; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic | 2007 |
Lipopolysaccharide enhances the production of nicotine-induced prostaglandin E2 by an increase in cyclooxygenase-2 expression in osteoblasts.
Topics: Alkaline Phosphatase; Base Sequence; Cell Line; Cell Proliferation; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; DNA Primers; Gene Expression; Humans; Indomethacin; Lipopolysaccharides; Macrophage Colony-Stimulating Factor; Nicotine; Osteoblasts; Receptors, Prostaglandin E | 2007 |
Nicotine promotes colon tumor growth and angiogenesis through beta-adrenergic activation.
Topics: Adrenergic beta-Agonists; Animals; Blotting, Western; Cell Survival; Cells, Cultured; Colonic Neoplasms; Cotinine; Cyclooxygenase 2; Dinoprostone; Epinephrine; HT29 Cells; Humans; Immunohistochemistry; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Nicotine; Nicotinic Agonists; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Reverse Transcriptase Polymerase Chain Reaction; Vascular Endothelial Growth Factor A | 2007 |
Nicotine and oxidative cigarette smoke constituents induce immune-modulatory and pro-inflammatory dendritic cell responses.
Topics: Adult; Animals; Antioxidants; Cell Differentiation; Cyclooxygenase 2; Dendritic Cells; Dinoprostone; Humans; Inflammation; Interleukin-8; Intracellular Space; Lung; Mice; Neutrophils; Nicotine; Oxidation-Reduction; Oxidative Stress; Smoking | 2008 |
Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and beta-adrenergic receptor signaling pathways.
Topics: Adenocarcinoma; alpha7 Nicotinic Acetylcholine Receptor; Bungarotoxins; Carcinogens; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclooxygenase 2; Dinoprostone; Gene Expression Regulation; Humans; Nicotine; Nitrosamines; p38 Mitogen-Activated Protein Kinases; Propranolol; Receptors, Adrenergic, beta; Receptors, Nicotinic; Signal Transduction; Stomach Neoplasms | 2008 |
Effects of nicotine and lipopolysaccharide on the expression of matrix metalloproteinases, plasminogen activators, and their inhibitors in human osteoblasts.
Topics: Alkaline Phosphatase; Celecoxib; Cell Proliferation; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Gene Expression Regulation; Humans; Lipopolysaccharides; Matrix Metalloproteinase 1; Matrix Metalloproteinases; Nicotine; Nicotinic Antagonists; Nitrobenzenes; Osteoblasts; Plasminogen Activators; Plasminogen Inactivators; Polymyxin B; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Tubocurarine | 2009 |
Acute nicotine reduces brain arachidonic acid signaling in unanesthetized rats.
Topics: Animals; Arachidonic Acid; Brain; Dinoprostone; Male; Mecamylamine; Nicotine; Rats; Rats, Inbred F344; Receptors, Nicotinic | 2009 |
Nicotine stimulates the expression of cyclooxygenase-2 mRNA via NFkappaB activation in human gingival fibroblasts.
Topics: Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Fibroblasts; Gingiva; Humans; Mecamylamine; NF-kappa B; Nicotine; Nicotinic Antagonists; RNA, Messenger; Transcriptional Activation | 2009 |
Anti-inflammatory effects of apigenin on nicotine- and lipopolysaccharide-stimulated human periodontal ligament cells via heme oxygenase-1.
Topics: Anti-Inflammatory Agents; Apigenin; Cell Line, Transformed; Cyclooxygenase 2; Cytokines; Dental Plaque; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Heme Oxygenase-1; Hemin; Humans; Lipopolysaccharides; Nicotine; Nitric Oxide; Nitric Oxide Synthase Type II; Periodontal Diseases; Periodontal Ligament; Phosphorylation; Smoking | 2009 |
Induction of COX-2/PGE(2)/IL-6 is crucial for cigarette smoke extract-induced airway inflammation: Role of TLR4-dependent NADPH oxidase activation.
Topics: Animals; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Enzyme Activation; Humans; Interleukin-6; Male; Mice; Mice, Inbred ICR; Myocytes, Smooth Muscle; NADPH Oxidases; Nicotine; Pneumonia; RNA, Small Interfering; Signal Transduction; Smoking; Toll-Like Receptor 4 | 2010 |
Effect of nicotine on advanced glycation end product-induced immune response in human monocytes.
Topics: alpha7 Nicotinic Acetylcholine Receptor; B7-2 Antigen; CD40 Antigens; Cell Proliferation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Dinoprostone; Glycation End Products, Advanced; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1; Interferon-gamma; Leukocytes, Mononuclear; Monocytes; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Tumor Necrosis Factor-alpha | 2010 |
Nicotine induces cyclooxygenase-2 and prostaglandin E(2) expression in human umbilical vein endothelial cells.
Topics: Blotting, Western; Cell Nucleus; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Electrophoretic Mobility Shift Assay; Endothelial Cells; Enzyme Induction; Female; Fluorescent Antibody Technique; Humans; Indicators and Reagents; Intercellular Adhesion Molecule-1; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pregnancy; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; Stimulation, Chemical; Umbilical Veins | 2010 |
Heme oxygenase-1 mediates nicotine- and lipopolysaccharide-induced expression of cyclooxygenase-2 and inducible nitric oxide synthase in human periodontal ligament cells.
Topics: Androstadienes; Anthracenes; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Enzyme Inhibitors; Heme Oxygenase-1; Humans; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Metalloporphyrins; NF-kappa B; Nicotine; Nitric Oxide; Nitric Oxide Synthase Type II; Periodontal Ligament; Phosphoinositide-3 Kinase Inhibitors; Protoporphyrins; RNA, Small Interfering; Transfection; Wortmannin | 2010 |
Differential effects of nicotine and tobacco smoke condensate on human annulus fibrosus cell metabolism.
Topics: Adult; Aged; Aggrecans; Cell Survival; Collagen Type I; Dinoprostone; Dose-Response Relationship, Drug; Female; Ganglionic Stimulants; Humans; Intervertebral Disc; Intervertebral Disc Degeneration; Male; Matrix Metalloproteinases; Middle Aged; Nicotine; Smoking; Young Adult | 2011 |
Nicotine and lipopolysaccharide stimulate the production of MMPs and prostaglandin E2 by hypoxia-inducible factor-1α up-regulation in human periodontal ligament cells.
Topics: Analysis of Variance; Cell Line, Transformed; Cyclooxygenase 2; Dinoprostone; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lipopolysaccharides; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Nicotine; Periodontal Ligament; Porphyromonas gingivalis; Statistics, Nonparametric; Up-Regulation | 2012 |
Effects of sirtuin 1 activation on nicotine and lipopolysaccharide-induced cytotoxicity and inflammatory cytokine production in human gingival fibroblasts.
Topics: Adenoviridae; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Cyclooxygenase 2; Dinoprostone; Fibroblasts; Genetic Vectors; Gingiva; Humans; Inflammation Mediators; Interleukins; Lipopolysaccharides; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinases; NF-kappa B; Nicotine; Nicotinic Agonists; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha; Up-Regulation | 2013 |
Change in nicotine-induced VEGF, PGE2 AND COX-2 expression following COX inhibition in human oral squamous cancer.
Topics: Carcinoma, Squamous Cell; Celecoxib; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Humans; Mouth Neoplasms; Nicotine; Phosphorylation; Pyrazoles; Sulfonamides; Vascular Endothelial Growth Factor A | 2012 |
Cigarette smoke condensate inhibits collagen gel contraction and prostaglandin E2 production in human gingival fibroblasts.
Topics: Actins; Blood; Cell Survival; Cells, Cultured; Collagen Type I; Connective Tissue Growth Factor; Cytochalasin D; Dinoprostone; Fibroblasts; Gels; Gingiva; Humans; Integrin beta1; Male; Matrix Metalloproteinase 3; Nicotiana; Nicotine; Smoke; Tissue Culture Techniques; Transforming Growth Factor beta1 | 2015 |
PIN1 inhibition suppresses osteoclast differentiation and inflammatory responses.
Topics: Adolescent; Adult; Aged; Animals; Anti-Inflammatory Agents; Cell Culture Techniques; Cell Differentiation; Culture Media, Conditioned; Cyclooxygenase 2; Dinoprostone; Female; Gene Knockdown Techniques; Genetic Vectors; Humans; Lipopolysaccharides; Male; Mice, Inbred ICR; Middle Aged; Naphthoquinones; NF-kappa B; Nicotine; NIMA-Interacting Peptidylprolyl Isomerase; Nitric Oxide; Nitric Oxide Synthase Type II; Osteoclasts; Peptidylprolyl Isomerase; Periodontal Ligament; Periodontitis; RNA, Small Interfering; Young Adult | 2015 |
Effects of different routes of nicotine administration on gastric morphology and hormonal secretion in rats.
Topics: Administration, Inhalation; Administration, Oral; Animals; Dinoprostone; Gastric Mucosa; Gastrins; Ghrelin; Histamine Release; Injections, Intraperitoneal; Male; Nicotine; Rats; Rats, Wistar | 2015 |
Nicotine-induced cellular stresses and autophagy in human cancer colon cells: A supportive effect on cell homeostasis via up-regulation of Cox-2 and PGE(2) production.
Topics: Apoptosis; Autophagy; Cell Line, Tumor; Colonic Neoplasms; Cyclooxygenase 2; Dinoprostone; Homeostasis; HT29 Cells; Humans; Nicotine; Reactive Oxygen Species; Signal Transduction; Up-Regulation | 2015 |
Anti-inflammatory and anti-osteoclastogenic effects of zinc finger protein A20 overexpression in human periodontal ligament cells.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cell Differentiation; Cells, Cultured; Dinoprostone; Gene Expression Profiling; Gingiva; Humans; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nicotine; Osteoclasts; Periodontal Ligament; Porphyromonas gingivalis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor alpha-Induced Protein 3; Up-Regulation | 2016 |
Complex osteoclastogenic inductive effects of nicotine over hydroxyapatite.
Topics: Actins; Adult; Calcium; Cell Differentiation; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Durapatite; Gene Expression Regulation; Humans; Macrophage Colony-Stimulating Factor; NF-kappa B; Nicotine; Osteoclasts; Osteogenesis; RANK Ligand; Signal Transduction; Tartrate-Resistant Acid Phosphatase; Time Factors; Tumor Necrosis Factor-alpha | 2018 |
Nicotine increases colon cancer cell migration and invasion through epithelial to mesenchymal transition (EMT): COX-2 involvement.
Topics: Antigens, CD; Antineoplastic Agents; beta Catenin; Caco-2 Cells; Cadherins; Carcinogens; Cell Movement; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Epithelial-Mesenchymal Transition; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Nicotine; Nitrobenzenes; Signal Transduction; Sulfonamides | 2018 |
Understanding the Interaction Between Prostaglandins and Toll-Like Receptors in Nicotine-Induced Rectal Tumor in Animals.
Topics: Animals; Cyclooxygenase 2; Dinoprostone; Mice; Nicotine; Prostaglandins; Rats; Rectal Neoplasms; Toll-Like Receptors | 2022 |