nicotine has been researched along with dihydro-beta-erythroidine in 196 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (4.08) | 18.7374 |
| 1990's | 33 (16.84) | 18.2507 |
| 2000's | 87 (44.39) | 29.6817 |
| 2010's | 62 (31.63) | 24.3611 |
| 2020's | 6 (3.06) | 2.80 |
| Authors | Studies |
|---|---|
| Adasme-Carreño, F; Alzate-Morales, J; Bermudez, I; Etcheverry-Berrios, A; Farias-Rabelo, N; Faundez-Parraguez, M; Gonzalez-Gutierrez, JP; Iturriaga-Vasquez, P; Varas, R | 1 |
| Clementi, F; Dallanoce, C; De Amici, M; Fiorentini, C; Fucile, S; Gotti, C; Grazioso, G; Matera, C; Missale, C; Pucci, L; Zoli, M | 1 |
| Myslinski, NR; Randić, M | 1 |
| Duggan, AW; Game, CJ | 1 |
| Eldred, E; Estavillo, J; Ginzel, KH | 1 |
| Ballivet, M; Bertrand, D; Bertrand, S | 1 |
| Bertrand, D; Bertrand, S; Changeux, JP; Devillers-Thiéry, A; Galzi, JL; Revah, F | 1 |
| Chiappinelli, VA; Sorenson, EM | 1 |
| Lipton, SA | 1 |
| Araujo, DM; Collier, B; Lapchak, PA; Quirion, R | 1 |
| Geertsen, S; Quik, M; Trifaró, JM | 1 |
| Kellar, KJ; Schwartz, RD | 1 |
| Damaj, MI; Martin, BR; Welch, SP | 1 |
| Gong, ZH; Hellström-Lindahl, E; Nordberg, A; Zhang, X | 1 |
| Khan, IM; Printz, MP; Taylor, P; Yaksh, TL | 1 |
| Adamson, KL; Coen, KM; Corrigall, WA | 1 |
| Clarke, PB; el-Bizri, H | 1 |
| Chiappinelli, VA; McMahon, LL; Yoon, KW | 1 |
| Khan, IM; Taylor, P; Yaksh, TL | 1 |
| Bertrand, D; Bertrand, S; Changeux, JP; Devillers-Thiéry, A; Eiselé, JL; Galzi, JL | 1 |
| Breese, GR; Criswell, HE; Yang, X | 1 |
| Hutson, P; Sullivan, JP; Wilkie, GI; Wonnacott, S | 1 |
| Changeux, JP; Léna, C | 1 |
| Chandler, CJ; Garcha, HS; Newton, JM; Stolerman, IP | 1 |
| Giaume, C; Glowinski, J; Hamon, B | 1 |
| Baptista, M; Yeomans, J | 1 |
| Akaike, A; Kaneko, S; Kimura, J; Kochiyama, H; Kume, T; Maeda, T; Shimohama, S | 1 |
| Buxton, ST; Crooks, PA; Dwoskin, LP; Teng, L | 1 |
| Epping-Jordan, MP; Koob, GF; Markou, A; Watkins, SS | 2 |
| Akaike, A; Kihara, T; Kimura, J; Kume, T; Maeda, T; Sawada, H; Shimohama, S; Urushitani, M | 1 |
| Lake, JR; Malin, DH; Rajan, N; Schweinle, WE; Shenoi, M; Upchurch, TP | 1 |
| Adcock, C; Baylis, HA; Buckingham, SD; Sansom, MS; Sattelle, DB | 1 |
| Paradiso, K; Sabey, K; Steinbach, JH; Zhang, J | 1 |
| Hanna, ST; Tang, G; Wang, R | 1 |
| Clarke, PB; Gioanni, Y; Lepousé, C; Rougeot, C; Thierry, AM; Vidal, C | 1 |
| Arneric, SP; Briggs, CA; Gopalakrishnan, M; McKenna, DG; Monteggia, LM; Roch, JM; Sullivan, JP; Touma, E | 1 |
| Dávila-García, MI; Houghtling, RA; Kellar, KJ; Qasba, SS | 1 |
| Bertrand, D; Chiodini, FC; Hulo, S; Muller, D; Tassonyi, E | 1 |
| Crooks, PA; Dwoskin, LP; Pauly, JR; Wilkins, LH | 1 |
| Lloyd, GK; Rao, TS; Reid, RT | 1 |
| Cohen, BN; Crooks, PA; Dwoskin, LP; Figl, A; Forsayeth, JR; Houng, M; Sandhu, S; Shafaee, N; Truong, A; Viseshakul, N | 1 |
| Bertrand, D; Blanchet, C; Raggenbass, M; Tribollet, E; Zaninetti, M | 1 |
| Alimohammadi, H; Silver, WL | 1 |
| Clarke, PB; Reuben, M | 1 |
| Corrigall, WA; Harding, JW; Juzytsch, W; Lê, AD; Li, TK | 1 |
| Adamson, KL; Chow, BL; Coen, KM; Corrigall, WA; Lança, AJ | 1 |
| Shoaib, M; Stolerman, IP; Zubaran, C | 1 |
| Blondel, A; Moser, PC; Sanger, DJ | 1 |
| Grillner, P; Svensson, TH | 1 |
| Changeux, JP; Klink, R; Korn, H; Léna, C; Tsuneki, H | 1 |
| Bancroft, A; Levin, ED | 1 |
| Gommans, J; Shoaib, M; Stolerman, IP | 1 |
| Dougherty, JJ; McIntosh, JM; Nayak, SV; Nichols, RA | 1 |
| Murakami, Y; Nakamura, K; Okada, S; Yokotani, K | 1 |
| Cherubini, E; Maggi, L; Sher, E | 1 |
| Akaike, N; Katsurabayashi, S; Kiyosawa, A; Pang, ZP | 1 |
| Bardo, MT; Crooks, PA; Dwoskin, LP; Green, TA | 1 |
| Cheeta, S; File, SE; Tucci, S | 1 |
| Broide, RS; Dani, JA; De Biasi, M; Ji, D; Patrick, JW; Paylor, R; Salas, R | 1 |
| Gasparini, F; Harrison, AA; Markou, A | 1 |
| Arthur, D; Levin, ED | 1 |
| Albuquerque, EX; Alkondon, M | 1 |
| Matsumoto, M; Ohashi, S; Saito, H; Togashi, H; Ueno, K; Yoshioka, M | 1 |
| Jeong, MS; Kim, CJ; Kim, KW; Park, EY; Park, JW; Shin, BS; Shin, MS; Woo, RS; Zhao, RJ | 1 |
| Ayers, JT; Crooks, PA; Dwoskin, LP; Grinevich, VP; Wilkins, LH | 1 |
| Laviolette, SR; van der Kooy, D | 1 |
| File, SE; Genn, RF; Tucci, SA | 1 |
| Markou, A; Skjei, KL | 1 |
| File, SE; Genn, RF; Marco, E; Tucci, S | 1 |
| Mameli-Engvall, M; Nomikos, GG; Rawal, N; Schilström, B; Svensson, TH | 1 |
| ESPELIEN, AD; EXLEY, KA; FLEMING, MC | 1 |
| Adams, P; Correa, LD; Rao, TS; Sacaan, AI; Santori, EM | 1 |
| Amano, T; Matsubayashi, H; Sakai, N; Sasa, M; Seki, T | 1 |
| Bai, G; Clark, CL; Martin, RJ; Robertson, AP | 1 |
| Höglund, AU; Kommalage, M | 1 |
| Barns, SM; Dajas-Bailador, F; Hejmadi, MV; Jones, B; Wonnacott, S | 1 |
| Al-Namaeh, M; Manaye, KF; Taylor, RE; Tizabi, Y | 1 |
| Ciotti, T; Eusebi, F; Fucile, S; Lauro, C; Limatola, C; Renzi, M | 1 |
| Greengard, P; Hamada, M; Higashi, H; Nairn, AC; Nishi, A | 1 |
| Bruijnzeel, AW; Markou, A | 1 |
| Amano, T; Inoue, A; Matsubayashi, H; Nakata, Y; Sakai, N; Sasa, M; Seki, T | 1 |
| Akaike, A; Kanki, R; Kawamata, J; Kihara, T; Nakamizo, T; Sawada, H; Shimohama, S; Yamashita, H | 1 |
| Evans, SP; Francis, MM; Jensen, M; Madsen, DM; Mancuso, J; Maricq, AV; Norman, KR | 1 |
| Changeux, JP; Corringer, PJ; Devillers-Thiery, A; Pons, S; Prado de Carvalho, L; Sallette, J; Soudant, M | 1 |
| Davis, JA; Gould, TJ | 2 |
| Araki, H; Gomita, Y; Jin, C; Kawasaki, H; Kawasaki, Y; Motoshima, S; Suemaru, K | 1 |
| Hamaue, N; Jia, Y; Sumikawa, K; Yamazaki, Y | 1 |
| Kenny, PJ; Markou, A | 1 |
| Barik, J; Wonnacott, S | 1 |
| Awtry, TL; Frank, JG; Werling, LL | 1 |
| Fadel, J; Pasumarthi, RK; Reznikov, LR | 1 |
| Chen, JT; Chen, XT; Lou, ZY; Luo, L; Ruan, DY; Sun, LG; Wang, HL; Wang, M; Wang, S | 1 |
| Jonkman, S; Markou, A | 1 |
| Guan, X; Nakauchi, S; Sumikawa, K | 1 |
| Briggs, CA; Gubbins, EJ; Marks, MJ; Meyer, MD; Putman, CB; Surowy, CS; Thimmapaya, R | 1 |
| Besson, M; Cazala, P; Changeux, JP; David, V; Granon, S | 1 |
| Chellappan, S; Dasgupta, P; Decook, C; Haura, E; Joshi, B; Kinkade, R | 1 |
| Borycz, J; Ciruela, F; Ferré, S; Franco, R; Goldberg, SR; Hope, BT; Lluis, C; Patkar, K; Quarta, D; Solinas, M; Wise, RA; Woods, AS | 1 |
| Icenogle, L; Levin, ED; Pocivavsek, A | 1 |
| Filip, M; McCreary, AC; Przegaliński, E; Zaniewska, M | 1 |
| Bitner, RS; Bratcher, NA; Decker, MW; Gopalakrishnan, M; Miner, HM; Radek, RJ | 1 |
| Caballero-Rivera, D; Lasalde-Dominicci, JA; Navedo, MF; Nieves-Cintrón, M | 1 |
| Bing, G; Chae, JS; Cheon, MA; Jung, ME; Kim, HC; Kim, WK; Ko, KH; Nah, SY; Shin, EJ; Wie, MB | 1 |
| Nakauchi, S; Sumikawa, K; Yamazaki, Y | 1 |
| Dar, MS; Smith, AD | 1 |
| Gould, TJ; Kenney, JW; Portugal, GS | 1 |
| Caggiula, AR; Donny, EC; Liu, X; Palmatier, MI; Sved, AF | 1 |
| Lester, H; Nashmi, R | 1 |
| Kawai, H; Lazar, R; Metherate, R | 1 |
| Davis, JA; Gould, TJ; Kenney, JW | 1 |
| Clements, MA; Cragg, SJ; Exley, R; Hartung, H; McIntosh, JM | 1 |
| Geyer, MA; Jonkman, S; Markou, A; Risbrough, VB | 1 |
| Feldman, JL; Fonck, C; Lester, HA; Puskar, N; Shao, XM; Tan, W; Xiu, J | 1 |
| Decker, MW; Man, K; Parikh, V; Sarter, M | 1 |
| Golmanesh, L; Mehrani, H | 1 |
| Bencan, Z; Levin, ED | 1 |
| Al-Rejaie, S; Saeed Dar, M; Taslim, N | 1 |
| Anand, R; Braunewell, KH; Zhao, C | 1 |
| Hu, J; Jin, G; Liu, Q; Lucero, L; Lukas, RJ; Wu, J; Yang, K; Zhen, X; Zheng, C | 1 |
| Araki, H; Gomita, Y; Kitamura, Y; Sagara, H; Sendo, T; Shibata, K; Suemaru, K; Yae, T | 1 |
| Fu, XW; Lindstrom, J; Spindel, ER | 1 |
| Good, CH; Lupica, CR | 1 |
| Hotta, H; Kawashima, K; Uchida, S | 1 |
| Gould, TJ; Gulick, D | 2 |
| Brotherton, J; Cannady, R; Gotschlich, E; Kolia, N; Lau, E; Levin, ED; Wee, B; Weir, R | 1 |
| Agrawal, R; Nath, C; Shukla, R; Tyagi, E | 1 |
| Fregosi, RF; Pilarski, JQ | 1 |
| Camarasa, J; Escubedo, E; Pubill, D; Ratés, SG | 1 |
| Bevins, RA; Crooks, PA; Dwoskin, LP; Struthers, AM; Wilkinson, JL | 1 |
| Izumi, T; Ohmura, Y; Tsutsui-Kimura, I; Yamaguchi, T; Yoshida, T; Yoshioka, M | 2 |
| Bailey, CD; De Biasi, M; Fletcher, PJ; Lambe, EK | 1 |
| Markou, A; Semenova, S | 1 |
| Carloni, P; Cherubini, E; Giorgetti, A; Griguoli, M; Maul, A; Nguyen, C | 1 |
| Gould, TJ; Raybuck, JD | 1 |
| Cunningham, CS; McMahon, LR | 2 |
| Feng, B; Guo, HJ; He, XS; Jia, D; Li, XQ; Liu, SB; Xing, JH; Zhao, MG | 1 |
| Buhlman, L; Jin, G; Khan, GM; Lukas, RJ; McIntosh, JM; Nichols, RA; Whiteaker, P; Wu, J; Yang, K | 1 |
| Lester, RA; Penton, RE; Quick, MW | 1 |
| Hahn, B; Shoaib, M; Stolerman, IP | 1 |
| Brooks, EA; Jutkiewicz, EM; Kynaston, AD; Rice, KC; Woods, JH | 1 |
| Moore, C; Ramage, AG; Wang, Y | 1 |
| Dani, JA; Dong, Y; Doyon, WM; Zhang, L | 1 |
| Bell, KA; Chen, CK; McQuiston, AR; Shim, H | 1 |
| Bailey, CD; De Biasi, M; Lambe, EK; Picciotto, MR; Tian, MK | 1 |
| Guo, L; Li, L; Pan, Z; Wang, W; Wu, Z; Zhou, Q | 1 |
| DeCuir, D; Gordon, CJ; Kellar, KJ; Levin, ED; Rezvani, AH; Sexton, HG; Timofeeva, O; Xiao, Y | 1 |
| Hayashi, M; Kawano, H; Kimura-Kuroda, J; Komuta, Y; Kuroda, Y | 1 |
| Nakauchi, S; Sumikawa, K | 1 |
| Rahman, S; Sajja, RK | 1 |
| Chen, Y; Ge, D; Wang, J; Yuan, W; Zhou, X | 1 |
| Fletcher, PJ; Guy, EG | 1 |
| Goshima, H; Ishizuka, T; Ozawa, A; Watanabe, Y | 1 |
| Alkadhi, KA; Alzoubi, KH; Srivareerat, M; Tran, TT | 1 |
| Galarraga, E; Galindo-Charles, L; Garduño, J; Hernandez-Lopez, S; Jiménez-Rodríguez, J; Mihailescu, S; Tapia, D | 1 |
| Bonfante-Cabarcas, R; Durand Mena, M; Ferrer Mancini, L; Fonseca Zambrano, R; Jiménez Hernández, E; López Hincapié, E; Rodríguez-Bonfante, C | 1 |
| Imad Damaj, M; Jackson, KJ | 1 |
| Cauley, M; Levin, ED; Rezvani, AH | 1 |
| Hashimoto, Y; Kang, HA; Kawai, HD; La, M; Lazar, R; Liang, K; Metherate, R | 1 |
| Bloem, B; Mansvelder, HD; Poorthuis, RB; Verhoog, MB | 1 |
| Huang, YY; Kandel, DB; Kandel, ER; Levine, A | 1 |
| Chen, P; Frenkel, M; Healy, FL; Lodge, NJ; Sivarao, DV; Zaczek, R | 1 |
| Grady, SR; Marks, MJ; Salminen, O; Soll, LG; Tapper, AR | 1 |
| Drucker-Colin, R; Frías-Domínguez, C; Garduño, J; Hernández, S; Mihailescu, S | 1 |
| Liu, X | 1 |
| Danielson, K; Kivell, BM; Putt, F; Truman, P | 1 |
| Feng, CS; Liu, Y; Piao, MH; Qiu, JP; Wang, YS | 1 |
| Braida, D; Gotti, C; Martucci, R; Ponzoni, L; Sala, M; Sparatore, F | 1 |
| Colom, LV; Kodirov, SA; Wehrmeister, M | 1 |
| Carter, CJ; Magoski, NS; White, SH | 1 |
| Carroll, FI; Cunningham, CS; McMahon, LR; Moura, FB; Ondachi, P; Rodriguez, JS | 1 |
| Lu, C; Wang, J; Wang, R; Wang, Y; Zhang, Q; Zhang, Y | 1 |
| Anderson, SM; Brunzell, DH | 1 |
| Gao, G; Gardner, PD; Liu, L; Ngolab, J; Tapper, AR; Zhao-Shea, R | 1 |
| Cahuzac, ELM; Lewis, AS; Mineur, YS; Picciotto, MR; Smith, PH | 1 |
| Carroll, FI; Freitas, K; Negus, SS | 1 |
| Leri, F; Vaccarino, FJ | 1 |
| Choe, ES; Choi, MJ; Lee, JY; Lee, YJ; Seo, JW; Yoon, SS | 1 |
| Eggan, BL; McCallum, SE | 1 |
| Alkahtani, RM; Grider, JR; Lyall, V; Mahavadi, S; Mummalaneni, SK; Murthy, KS; Qian, J | 1 |
| de Moura, FB; McMahon, LR | 1 |
| Izumi, T; Ohmura, Y; Sasamori, H; Tsutsui-Kimura, I; Yoshida, T; Yoshioka, M | 1 |
| Kato, T; Kawano, T; Sato, H; Toyoda, H; Yin, DX | 1 |
| Barrett, ST; Bevins, RA; Geary, TN; Steiner, AN | 1 |
| Fletcher, PJ; Tabbara, RI | 1 |
| Abd-Alhaseeb, MM; El-Gowilly, SM; El-Mas, MM; Fouda, MA; Sallam, MY | 1 |
| Diao, Y; Han, T; Lai, R; Wang, Q; Yin, Y; Zhang, D | 1 |
| de Moura, FB; McMahon, LR; Wilkerson, JL | 1 |
| Fronius, M; Hollenhorst, MI; Krasteva-Christ, G; Kumar, P; Scholze, P | 1 |
| Deyama, S; Esaki, H; Fukao, A; Ito, S; Izumi, S; Kaneda, K; Nishitani, N | 1 |
| Winger, G | 2 |
1 review(s) available for nicotine and dihydro-beta-erythroidine
| Article | Year |
|---|---|
Tribute to: Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area [William Corrigall, Kathleen Coen and Laurel Adamson, Brain Res. 653 (1994) 278-284].
Topics: Animals; Dihydro-beta-Erythroidine; Dopaminergic Neurons; History, 20th Century; Humans; Neurosciences; Nicotine; Nicotinic Antagonists; Nucleus Accumbens; Rats; Receptors, Nicotinic; Reinforcement, Psychology; Self Administration; Ventral Tegmental Area | 2016 |
195 other study(ies) available for nicotine and dihydro-beta-erythroidine
| Article | Year |
|---|---|
Neonicotinic analogues: selective antagonists for α4β2 nicotinic acetylcholine receptors.
Topics: Humans; Nicotinic Agonists; Receptors, Nicotinic; Structure-Activity Relationship | 2013 |
Bifunctional compounds targeting both D2 and non-α7 nACh receptors: design, synthesis and pharmacological characterization.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Design; HEK293 Cells; Humans; Molecular Structure; Nicotinic Antagonists; Receptors, Dopamine D2; Structure-Activity Relationship; Substrate Specificity | 2015 |
Responses of identified spinal neurones to acetylcholine applied by micro-electrophoresis.
Topics: Acetylcholine; Animals; Atropine; Cats; Choline; Dihydro-beta-Erythroidine; Electrophoresis; Evoked Potentials; Female; Interneurons; Male; Methacholine Compounds; Neurons; Nicotine; Spinal Cord | 1977 |
The sensitivity of paramedian reticular neurones to acetylcholine.
Topics: Acetylcholine; Animals; Atropine; Cats; Cerebellum; Cranial Nerves; Dihydro-beta-Erythroidine; Gallamine Triethiodide; Glutamates; Laryngeal Nerves; Medulla Oblongata; Neurons; Nicotine; Norepinephrine; Olivary Nucleus; Receptors, Cholinergic; Reticular Formation | 1975 |
Nicotine-induced reflex depression of alpha motoneuron activity in the absence of fusimotor-spindle feedback.
Topics: Acetylcholine; Animals; Cats; Choline; Depression, Chemical; Dihydro-beta-Erythroidine; Feedback; Motor Neurons; Nicotine; Reflex; Reflex, Monosynaptic; Spinal Cord; Vagotomy | 1975 |
Pharmacological properties of the homomeric alpha 7 receptor.
Topics: Acetylcholine; Alkaloids; Animals; Azocines; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Hexamethonium Compounds; Nicotine; Oocytes; Quinolizines; Receptors, Cholinergic; Receptors, Nicotinic; Tubocurarine; Xenopus | 1992 |
Functional significance of aromatic amino acids from three peptide loops of the alpha 7 neuronal nicotinic receptor site investigated by site-directed mutagenesis.
Topics: Acetylcholine; Amino Acid Sequence; Animals; Bungarotoxins; Chickens; Dihydro-beta-Erythroidine; Electrophysiology; Female; Ion Channel Gating; Molecular Sequence Data; Mutagenesis, Site-Directed; Neurons; Nicotine; Oocytes; Receptors, Nicotinic; Torpedo; Transfection; Tryptophan; Tyrosine; Xenopus | 1991 |
Intracellular recording in avian brain of a nicotinic response that is insensitive to K-bungarotoxin.
Topics: Animals; Autoradiography; Brain; Bungarotoxins; Carbachol; Chickens; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electrophysiology; Female; Intracellular Membranes; Neurons; Nicotine; Osmolar Concentration; Tubocurarine | 1990 |
Spontaneous release of acetylcholine affects the physiological nicotinic responses of rat retinal ganglion cells in culture.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Cells, Cultured; Choline O-Acetyltransferase; Cobalt; Dihydro-beta-Erythroidine; Ganglionic Blockers; Immunohistochemistry; Magnesium; Membrane Potentials; Nicotine; Rats; Receptors, Nicotinic; Retina; Retinal Ganglion Cells; Tubocurarine | 1988 |
Characterization of N-[3H]methylcarbamylcholine binding sites and effect of N-methylcarbamylcholine on acetylcholine release in rat brain.
Topics: Acetylcholine; Animals; Binding, Competitive; Brain; Bungarotoxins; Carbachol; Choline; Corpus Striatum; Dihydro-beta-Erythroidine; Frontal Lobe; Hippocampus; Male; Nicotine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Tubocurarine | 1988 |
Marked up-regulation of the beta-bungarotoxin site in adrenal chromaffin cells by specific nicotinic antagonists.
Topics: Adrenal Medulla; alpha7 Nicotinic Acetylcholine Receptor; Animals; Binding, Competitive; Bungarotoxins; Carbachol; Cattle; Chromaffin Granules; Chromaffin System; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Hexamethonium Compounds; Mecamylamine; Nicotine; Receptors, Cholinergic; Receptors, Nicotinic; Tetrodotoxin; Tubocurarine; Veratridine | 1987 |
In vivo regulation of [3H]acetylcholine recognition sites in brain by nicotinic cholinergic drugs.
Topics: Acetylcholine; Alkaloids; Animals; Azocines; Brain; Cerebral Cortex; Corpus Striatum; Cotinine; Dihydro-beta-Erythroidine; Ganglionic Stimulants; Hypothalamus; Isoflurophate; Male; Mecamylamine; Nicotine; Quinolizines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Muscarinic; Thalamus | 1985 |
In vivo pharmacological effects of dihydro-beta-erythroidine, a nicotinic antagonist, in mice.
Topics: Analgesics; Animals; Behavior, Animal; Body Temperature; Brain; Dihydro-beta-Erythroidine; Hexamethonium Compounds; In Vitro Techniques; Injections, Spinal; Kinetics; Male; Mecamylamine; Mice; Mice, Inbred ICR; Movement; Nicotine; Nicotinic Antagonists | 1995 |
Regulation of alpha 4 beta 2 nicotinic acetylcholine receptors in M10 cells following treatment with nicotinic agents.
Topics: Alkaloids; Animals; Azocines; Cell Line; Dihydro-beta-Erythroidine; Hexamethonium; Mice; Models, Biological; Nicotine; Quinolizines; Receptors, Nicotinic; Tubocurarine | 1995 |
Augmented responses to intrathecal nicotinic agonists in spontaneous hypertension.
Topics: Aconitine; Alkaloids; Animals; Azocines; Blood Pressure; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Injections, Spinal; Male; Mecamylamine; Motor Activity; Nicotine; Nicotinic Agonists; Quinolizines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spinal Cord; Stereotyped Behavior | 1994 |
Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area.
Topics: Animals; Atropine; Cocaine; Dihydro-beta-Erythroidine; Dopamine; Food; Limbic System; Male; Microinjections; Motor Activity; Nicotine; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Self Administration; Tegmentum Mesencephali | 1994 |
Blockade of nicotinic receptor-mediated release of dopamine from striatal synaptosomes by chlorisondamine and other nicotinic antagonists administered in vitro.
Topics: Animals; Calcium; Chlorisondamine; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Dopamine; Ganglionic Stimulants; In Vitro Techniques; Male; Mecamylamine; Neostriatum; Nicotine; Nicotinic Antagonists; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Synaptosomes | 1994 |
Nicotinic receptor activation facilitates GABAergic neurotransmission in the avian lateral spiriform nucleus.
Topics: Animals; Bicuculline; Bungarotoxins; Carbachol; Chick Embryo; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Evoked Potentials; gamma-Aminobutyric Acid; Membrane Potentials; Mesencephalon; Neurons; Nicotine; Nicotinic Antagonists; Receptors, Nicotinic; Sodium Channel Blockers; Sodium Channels; Synaptic Transmission; Tetrodotoxin | 1994 |
Cardiovascular and behavioral responses to nicotinic agents administered intrathecally.
Topics: Aconitine; Alkaloids; Animals; Atropine; Azocines; Behavior, Animal; Blood Pressure; Bungarotoxins; Cardiovascular System; Dihydro-beta-Erythroidine; Ganglionic Stimulants; Heart Rate; Injections, Spinal; Lobeline; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Nociceptors; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Sensitivity and Specificity; Spinal Cord; Trimethaphan | 1994 |
Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities.
Topics: Acetylcholine; Amino Acid Sequence; Animals; Binding Sites; Bungarotoxins; Calcium; Curare; Dihydro-beta-Erythroidine; Ion Channel Gating; Molecular Sequence Data; Nicotine; Oocytes; Receptors, Nicotinic; Receptors, Serotonin; Recombinant Fusion Proteins; Serotonin; Xenopus | 1993 |
Nicotine-induced inhibition in medial septum involves activation of presynaptic nicotinic cholinergic receptors on gamma-aminobutyric acid-containing neurons.
Topics: Animals; Bicuculline; Dihydro-beta-Erythroidine; gamma-Aminobutyric Acid; Magnesium; Male; Neurons; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Presynaptic; Septum Pellucidum | 1996 |
Pharmacological characterization of a nicotinic autoreceptor in rat hippocampal synaptosomes.
Topics: Acetylcholine; Aconitine; Animals; Calcium; Choline; Dihydro-beta-Erythroidine; Hippocampus; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pempidine; Potassium Chloride; Rats; Receptors, Nicotinic; Synaptosomes | 1996 |
Role of Ca2+ ions in nicotinic facilitation of GABA release in mouse thalamus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Action Potentials; Alkaloids; Animals; Arousal; Atropine; Azocines; Bacterial Toxins; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channel Blockers; Calcium Channels; Carbachol; Cations, Divalent; Cyanobacteria Toxins; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; GABA Antagonists; gamma-Aminobutyric Acid; Ion Transport; Lobeline; Marine Toxins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcystins; Neurons, Afferent; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Potassium; Pyridazines; Pyridines; Quinolizines; Receptors, GABA-A; Receptors, Nicotinic; Tetrodotoxin; Thalamic Nuclei | 1997 |
Selective antagonism of behavioural effects of nicotine by dihydro-beta-erythroidine in rats.
Topics: Animals; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Interactions; Locomotion; Male; Nicotine; Rats | 1997 |
Nicotine inhibits slowly inactivating K+ currents in rat cultured striatal neurons.
Topics: Acetylcholine; Animals; Cells, Cultured; Corpus Striatum; Dihydro-beta-Erythroidine; Electric Conductivity; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Potassium; Rats; Rats, Sprague-Dawley | 1997 |
Both nicotinic and muscarinic receptors in ventral tegmental area contribute to brain-stimulation reward.
Topics: Animals; Atropine; Dihydro-beta-Erythroidine; Male; Mecamylamine; Microinjections; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic; Reward; Self Stimulation; Ventral Tegmental Area | 1997 |
Nicotine protects cultured cortical neurons against glutamate-induced cytotoxicity via alpha7-neuronal receptors and neuronal CNS receptors.
Topics: Aconitine; Animals; Bungarotoxins; Cell Survival; Cells, Cultured; Cerebral Cortex; Cysteine; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; Glutamic Acid; Ionomycin; Ionophores; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Antagonists; Rats; Receptors, Nicotinic; S-Nitrosothiols; Toxins, Biological | 1997 |
Nicotinic-receptor mediation of S(-)nornicotine-evoked -3H-overflow from rat striatal slices preloaded with -3H-dopamine.
Topics: Animals; Corpus Striatum; Dihydro-beta-Erythroidine; Dopamine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mecamylamine; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Stereoisomerism; Tritium | 1997 |
Dramatic decreases in brain reward function during nicotine withdrawal.
Topics: Animals; Brain; Dihydro-beta-Erythroidine; Disease Models, Animal; Infusion Pumps, Implantable; Male; Motivation; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Reward; Self Stimulation; Sensory Thresholds; Substance Withdrawal Syndrome | 1998 |
Stimulation of alpha4beta2 nicotinic acetylcholine receptors inhibits beta-amyloid toxicity.
Topics: Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Animals; Azocines; Bungarotoxins; Cells, Cultured; Cerebral Cortex; Dihydro-beta-Erythroidine; Fetus; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Quinolizines; Rats; Receptors, Nicotinic | 1998 |
Nicotine abstinence syndrome precipitated by the competitive nicotinic antagonist dihydro-beta-erythroidine.
Topics: Animals; Cholinergic Agents; Dihydro-beta-Erythroidine; Injections, Intraventricular; Male; Muscarinic Antagonists; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Scopolamine; Substance Withdrawal Syndrome; Substance-Related Disorders | 1998 |
Functional characterization of a mutated chicken alpha7 nicotinic acetylcholine receptor subunit with a leucine residue inserted in transmembrane domain 2.
Topics: Acetylcholine; Amino Acid Sequence; Animals; Anthelmintics; Base Sequence; Chickens; Dihydro-beta-Erythroidine; Female; In Vitro Techniques; Leucine; Levamisole; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nicotine; Nicotinic Agonists; Oocytes; Protein Conformation; Receptors, Nicotinic; Xenopus laevis | 1998 |
Ligand binding and activation of rat nicotinic alpha4beta2 receptors stably expressed in HEK293 cells.
Topics: Acetylcholine; Alkaloids; Animals; Azocines; Calcium; Dihydro-beta-Erythroidine; Humans; Nicotine; Physostigmine; Quinolizines; Rats; Receptors, GABA-A; Receptors, Nicotinic; Recombinant Proteins | 1999 |
Effects of nicotine on K+ channel currents in vascular smooth muscle cells from rat tail arteries.
Topics: 4-Aminopyridine; Animals; Arteries; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Sprague-Dawley; Tail; Tetraethylammonium | 1999 |
Nicotinic receptors in the rat prefrontal cortex: increase in glutamate release and facilitation of mediodorsal thalamo-cortical transmission.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Animals; Autoradiography; Cerebral Cortex; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Insecticides; Locomotion; Male; Mecamylamine; Microdialysis; Neural Pathways; Neurons, Afferent; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Reaction Time; Receptors, Nicotinic; Synaptic Transmission; Thalamus; Tritium | 1999 |
Gain of function mutation of the alpha7 nicotinic receptor: distinct pharmacology of the human alpha7V274T variant.
Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amino Acid Substitution; Animals; Atropine; Choline; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Genetic Variation; Humans; Lobeline; Mecamylamine; Membrane Potentials; Muscarinic Antagonists; Mutation; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oocytes; Pyridines; Pyrrolidines; Receptors, Nicotinic; Threonine; Tubocurarine; Valine; Xenopus | 1999 |
Nicotinic receptor binding sites in rat primary neuronal cells in culture: characterization and their regulation by chronic nicotine.
Topics: Acetylcholine; Alkaloids; Animals; Azocines; Binding, Competitive; Brain Chemistry; Brain Stem; Cells, Cultured; Cerebral Cortex; Dihydro-beta-Erythroidine; Female; Mecamylamine; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pregnancy; Quinolizines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Tritium | 1999 |
Blockade of nicotine self-administration with nicotinic antagonists in rats.
Topics: Animals; Conditioning, Operant; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic; Reinforcement Schedule; Self Administration | 1999 |
Modulation of synaptic transmission by nicotine and nicotinic antagonists in hippocampus.
Topics: Aconitine; Animals; Dihydro-beta-Erythroidine; Hippocampus; In Vitro Techniques; Mecamylamine; Neural Inhibition; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1999 |
Development of a novel class of subtype-selective nicotinic receptor antagonist: pyridine-N-substituted nicotine analogs.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Corpus Striatum; Dihydro-beta-Erythroidine; Dopamine; Nicotine; Nicotinic Antagonists; Pyridines; Rats; Receptors, Nicotinic; Rubidium; Synaptosomes | 1999 |
Pharmacological characterization of nicotine-induced acetylcholine release in the rat hippocampus in vivo: evidence for a permissive dopamine synapse.
Topics: Acetylcholine; Animals; Benzazepines; Dihydro-beta-Erythroidine; Dopamine Antagonists; Dose-Response Relationship, Drug; Hippocampus; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Synapses | 1999 |
Pharmacological similarities between native brain and heterologously expressed alpha4beta2 nicotinic receptors.
Topics: Animals; Antibodies, Monoclonal; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Dihydro-beta-Erythroidine; Female; Gene Expression; Humans; Kinetics; Nicotine; Oocytes; Precipitin Tests; Pyridines; Rats; Receptors, Nicotinic; Recombinant Fusion Proteins; Tritium; Xenopus | 1999 |
Magnocellular neurons of the rat supraoptic nucleus are endowed with functional nicotinic acetylcholine receptors.
Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electrophysiology; In Vitro Techniques; Iodine Radioisotopes; Male; Membrane Potentials; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Supraoptic Nucleus; Tritium; Vasodilator Agents | 2000 |
Evidence for nicotinic acetylcholine receptors on nasal trigeminal nerve endings of the rat.
Topics: Alkaloids; Analysis of Variance; Animals; Cyclohexanones; Dihydro-beta-Erythroidine; Ganglionic Blockers; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Nose; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Receptors, Nicotinic; Trigeminal Nerve | 2000 |
Nicotine-evoked [3H]5-hydroxytryptamine release from rat striatal synaptosomes.
Topics: 4-Aminopyridine; Animals; Corpus Striatum; Dihydro-beta-Erythroidine; Ganglionic Blockers; Ganglionic Stimulants; Hippocampus; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Recombinant Proteins; Serotonin; Synaptosomes; Veratridine; Visual Cortex | 2000 |
Involvement of nicotinic receptors in alcohol self-administration.
Topics: Alcohol Drinking; Animals; Conditioning, Operant; Dihydro-beta-Erythroidine; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic; Self Administration | 2000 |
The pedunculopontine tegmental nucleus and the role of cholinergic neurons in nicotine self-administration in the rat: a correlative neuroanatomical and behavioral study.
Topics: Acetylcholine; Animals; Aziridines; Behavior, Animal; Choline; Cholinergic Fibers; Denervation; Dihydro-beta-Erythroidine; Excitatory Amino Acid Agonists; Ibotenic Acid; Male; Nerve Degeneration; Neuromuscular Blocking Agents; Neurons; Neurotoxins; Nicotine; Nicotinic Agonists; Pons; Rats; Rats, Long-Evans; Self Administration; Tegmentum Mesencephali; Tobacco Use Disorder | 2000 |
Antagonism of stimulus properties of nicotine by dihydro-beta-erythroidine (DHbetaE) in rats.
Topics: Analysis of Variance; Animals; Conditioning, Psychological; Dihydro-beta-Erythroidine; Discrimination Learning; Drug Antagonism; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Taste | 2000 |
Characterisation of the effects of nicotine in the five-choice serial reaction time task in rats: antagonist studies.
Topics: Aconitine; Animals; Dihydro-beta-Erythroidine; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Reaction Time | 2000 |
Nicotine-induced excitation of midbrain dopamine neurons in vitro involves ionotropic glutamate receptor activation.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Action Potentials; Animals; Dihydro-beta-Erythroidine; Dopamine; In Vitro Techniques; Insecticides; Mecamylamine; Neurons; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Ventral Tegmental Area | 2000 |
Calcium mobilization elicited by two types of nicotinic acetylcholine receptors in mouse substantia nigra pars compacta.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Action Potentials; Animals; Benzoates; Bungarotoxins; Calcium; Calcium Channel Blockers; Choline; Dihydro-beta-Erythroidine; Endoplasmic Reticulum; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Glycine; In Vitro Techniques; Indoles; Insecticides; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neurons; Nicotine; Nicotinic Agonists; Nifedipine; Nootropic Agents; Patch-Clamp Techniques; Polyamines; Presynaptic Terminals; Receptors, Nicotinic; Substantia Nigra; Tetrodotoxin; Tyrosine 3-Monooxygenase | 2000 |
Ventral hippocampal alpha4beta2 nicotinic receptors and chronic nicotine effects on memory.
Topics: Animals; Behavior, Animal; Dihydro-beta-Erythroidine; Female; Hippocampus; Maze Learning; Memory; Memory, Short-Term; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2000 |
Antagonism of the discriminative and aversive stimulus properties of nicotine in C57BL/6J mice.
Topics: Aconitine; Animals; Avoidance Learning; Behavior, Animal; Dihydro-beta-Erythroidine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Reinforcement, Psychology; Taste | 2000 |
Ca(2+) changes induced by different presynaptic nicotinic receptors in separate populations of individual striatal nerve terminals.
Topics: Animals; Bungarotoxins; Calcium; Corpus Striatum; Dihydro-beta-Erythroidine; Kinetics; Male; Microscopy, Confocal; Neurons; Nicotine; Potassium Chloride; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Synaptosomes | 2001 |
Nicotinic receptors involved in gastric noradrenaline release evoked by electrical stimulation of the splanchnic nerve in rats.
Topics: Animals; Atropine; Bungarotoxins; Calcium Channel Blockers; Conotoxins; Dihydro-beta-Erythroidine; Diltiazem; Electric Stimulation; Gastric Mucosa; Hexamethonium; In Vitro Techniques; Male; Mecamylamine; Nicotine; Norepinephrine; Rats; Rats, Wistar; Receptors, Nicotinic; Splanchnic Nerves; Stomach | 2001 |
Regulation of GABA release by nicotinic acetylcholine receptors in the neonatal rat hippocampus.
Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Animals, Newborn; Bicuculline; Bridged-Ring Compounds; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Insecticides; Membrane Potentials; Nicotine; Nicotinic Agonists; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Nicotinic; Spiro Compounds | 2001 |
Nicotine facilitates glycine release in the rat spinal dorsal horn.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha7 Nicotinic Acetylcholine Receptor; Anesthetics, Local; Animals; Bacterial Toxins; Bicuculline; Bungarotoxins; Calcium; Calcium Channels; Choline; Cyanobacteria Toxins; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Marine Toxins; Mecamylamine; Microcystins; Nerve Endings; Neural Inhibition; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nootropic Agents; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Nicotinic; Substantia Gelatinosa; Tetrodotoxin; Tropanes; Valine | 2001 |
Contributory role for nornicotine in nicotine neuropharmacology: nornicotine-evoked [3H]dopamine overflow from rat nucleus accumbens slices.
Topics: Analysis of Variance; Animals; Calcium; Dihydro-beta-Erythroidine; Dopamine; In Vitro Techniques; Insecticides; Male; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Smoking; Tritium | 2001 |
Antagonism of the anxiolytic effect of nicotine in the dorsal raphe nucleus by dihydro-beta-erythroidine.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Dihydro-beta-Erythroidine; Male; Nicotine; Nicotinic Agonists; Raphe Nuclei; Rats; Receptors, Nicotinic; Social Behavior | 2001 |
Increased sensitivity to nicotine-induced seizures in mice expressing the L250T alpha 7 nicotinic acetylcholine receptor mutation.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amino Acid Substitution; Animals; Dihydro-beta-Erythroidine; Disease Models, Animal; Electrophysiology; Female; Ganglionic Stimulants; Heterozygote; Hippocampus; Lysine; Male; Mice; Mice, Inbred C57BL; Neuroanatomy; Nicotine; Phenotype; Receptors, Nicotinic; Seizures; Threonine | 2002 |
Nicotine potentiation of brain stimulation reward reversed by DH beta E and SCH 23390, but not by eticlopride, LY 314582 or MPEP in rats.
Topics: Animals; Benzazepines; Brain; Bridged Bicyclo Compounds; Dihydro-beta-Erythroidine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Dopamine D1; Receptors, Metabotropic Glutamate; Receptors, Nicotinic; Reward; Salicylamides | 2002 |
Chronic inhibition of alpha4beta2 nicotinic receptors in the ventral hippocampus of rats: impacts on memory and nicotine response.
Topics: Alzheimer Disease; Animals; Cognition Disorders; Dihydro-beta-Erythroidine; Female; Hippocampus; Memory; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Time Factors | 2002 |
A non-alpha7 nicotinic acetylcholine receptor modulates excitatory input to hippocampal CA1 interneurons.
Topics: Acetylcholine; Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Animals; Azocines; Choline; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Excitatory Postsynaptic Potentials; Hippocampus; Interneurons; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2002 |
Alpha4beta2 nicotinic acetylcholine receptor activation ameliorates impairment of spontaneous alternation behavior in stroke-prone spontaneously hypertensive rats, an animal model of attention deficit hyperactivity disorder.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Central Nervous System Agents; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Hexamethonium; Hypertension; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Peripheral Nervous System; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Nicotinic | 2002 |
Mechanism of nicotine-evoked release of 3H-noradrenaline in human cerebral cortex slices.
Topics: Adolescent; Adult; Arginine; Calcium; Calcium Channel Blockers; Cerebral Cortex; Dihydro-beta-Erythroidine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoxetine; Ganglionic Stimulants; Guanylate Cyclase; Humans; In Vitro Techniques; Indazoles; Male; Mecamylamine; Methylene Blue; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nicotine; Nicotinic Antagonists; Nitrendipine; Nitric Oxide Synthase; Norepinephrine; omega-Conotoxin GVIA; Oxadiazoles; Purinones; Quinoxalines; Tetrodotoxin; Tritium; Tubocurarine | 2002 |
N-n-alkylnicotinium analogs, a novel class of nicotinic receptor antagonists: interaction with alpha4beta2* and alpha7* neuronal nicotinic receptors.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Binding Sites; Binding, Competitive; Brain; Dihydro-beta-Erythroidine; Dopamine; In Vitro Techniques; Kinetics; Male; Membranes; Neostriatum; Neurons; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Structure-Activity Relationship | 2003 |
The motivational valence of nicotine in the rat ventral tegmental area is switched from rewarding to aversive following blockade of the alpha7-subunit-containing nicotinic acetylcholine receptor.
Topics: 2-Amino-5-phosphonovalerate; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Conditioning, Operant; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Microinjections; Motivation; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Reinforcement, Psychology; Reward; Ventral Tegmental Area | 2003 |
Methyllycaconitine (MLA) blocks the nicotine evoked anxiogenic effect and 5-HT release in the dorsal hippocampus: possible role of alpha7 receptors.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anxiety; Behavior, Animal; Cholinergic Antagonists; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Interpersonal Relations; Male; Motor Activity; Nicotine; Nicotinic Antagonists; Random Allocation; Rats; Receptors, Nicotinic; Serotonin; Time Factors | 2003 |
Effects of repeated withdrawal episodes, nicotine dose, and duration of nicotine exposure on the severity and duration of nicotine withdrawal in rats.
Topics: Animals; Central Nervous System Stimulants; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Infusion Pumps, Implantable; Male; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Reward; Self Stimulation; Sensory Thresholds; Substance Withdrawal Syndrome | 2003 |
Do different mechanisms underlie two anxiogenic effects of systemic nicotine?
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anxiety; Behavior, Animal; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Piperazines; Pyridines; Rats; Receptor, Serotonin, 5-HT1A; Receptors, Nicotinic; Serotonin Antagonists; Social Behavior | 2003 |
Dual effects of nicotine on dopamine neurons mediated by different nicotinic receptor subtypes.
Topics: Aconitine; Action Potentials; Analysis of Variance; Animals; Brain; Dihydro-beta-Erythroidine; Dopamine; Dose-Response Relationship, Drug; Male; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oncogene Proteins v-fos; Protein Subunits; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Nicotinic | 2003 |
Effects of drugs which depress the peripheral nervous system on the reticular activating system of the cat.
Topics: Acetylcholine; Animals; Atropine; Brain Stem; Cats; Choline; Dihydro-beta-Erythroidine; Humans; Mecamylamine; Nicotine; Peripheral Nervous System; Physostigmine; Scopolamine | 1958 |
Pharmacological characterization of dopamine, norepinephrine and serotonin release in the rat prefrontal cortex by neuronal nicotinic acetylcholine receptor agonists.
Topics: Alkaloids; Animals; Azocines; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Dopamine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mecamylamine; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Norepinephrine; Prefrontal Cortex; Pyridines; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Serotonin; Tetrodotoxin | 2003 |
Electrophysiological characterization of nicotine-induced excitation of dopaminergic neurons in the rat substantia nigra.
Topics: Animals; Dihydro-beta-Erythroidine; Dopamine; Dose-Response Relationship, Drug; Electrophysiology; Membrane Potentials; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Rats; Receptors, Neurotransmitter; Receptors, Nicotinic; Substantia Nigra | 2003 |
Methyridine (2-[2-methoxyethyl]-pyridine]) and levamisole activate different ACh receptor subtypes in nematode parasites: a new lead for levamisole-resistance.
Topics: Animals; Antinematodal Agents; Ascaris suum; Bephenium Compounds; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Resistance; Indolizines; Isometric Contraction; Larva; Levamisole; Mecamylamine; Membrane Potentials; Muscles; Nicotine; Nicotinic Antagonists; Protein Isoforms; Pyrantel; Pyridines; Receptors, Nicotinic; Spiro Compounds | 2003 |
Nicotinic acetylcholinergic receptors regulate the intraspinal release of acetylcholine in male rats.
Topics: Acetylcholine; Aconitine; Animals; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Male; Mecamylamine; Microdialysis; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Spinal Cord; Time Factors | 2003 |
Neuroprotection by nicotine against hypoxia-induced apoptosis in cortical cultures involves activation of multiple nicotinic acetylcholine receptor subtypes.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Apoptosis; Bungarotoxins; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Dihydro-beta-Erythroidine; DNA Damage; Hypoxia-Ischemia, Brain; Neurons; Neuroprotective Agents; Nicotine; Rats; Rats, Wistar; Receptors, Nicotinic | 2003 |
Protective effects of nicotine on ethanol-induced toxicity in cultured cerebellar granule cells.
Topics: Aconitine; Animals; Cells, Cultured; Central Nervous System Depressants; Cerebellum; Culture Media; Dihydro-beta-Erythroidine; Ethanol; Female; L-Lactate Dehydrogenase; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2003 |
Nicotinic cholinergic stimulation promotes survival and reduces motility of cultured rat cerebellar granule cells.
Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Calcium Signaling; Cell Differentiation; Cell Movement; Cell Survival; Cells, Cultured; Cerebellar Cortex; Dihydro-beta-Erythroidine; Drug Interactions; Humans; Indoles; Membrane Potentials; Neurons; Nicotine; Potassium Deficiency; Rats; Receptors, Nicotinic | 2004 |
Differential regulation of dopamine D1 and D2 signaling by nicotine in neostriatal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzazepines; Blotting, Western; Bungarotoxins; Cyclosporine; Dihydro-beta-Erythroidine; Dizocilpine Maleate; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Models, Neurological; Neostriatum; Nerve Tissue Proteins; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phosphoproteins; Phosphorylation; Raclopride; Receptors, Dopamine D1; Receptors, Dopamine D2; Tetrodotoxin; Threonine | 2004 |
Adaptations in cholinergic transmission in the ventral tegmental area associated with the affective signs of nicotine withdrawal in rats.
Topics: Adaptation, Physiological; Animals; Cholinergic Fibers; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Male; Nicotine; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Synaptic Transmission; Ventral Tegmental Area | 2004 |
Involvement of alpha7- and alpha4beta2-type postsynaptic nicotinic acetylcholine receptors in nicotine-induced excitation of dopaminergic neurons in the substantia nigra: a patch clamp and single-cell PCR study using acutely dissociated nigral neurons.
Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Atropine; Cells, Cultured; Dihydro-beta-Erythroidine; Dopamine; Muscarinic Antagonists; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Polymerase Chain Reaction; Rats; Rats, Wistar; Receptors, Nicotinic; Substantia Nigra | 2004 |
Stimulation of nicotinic acetylcholine receptors protects motor neurons.
Topics: Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Cell Death; Cell Survival; Cells, Cultured; Cholinesterase Inhibitors; Dihydro-beta-Erythroidine; Fetus; Galantamine; Glutamic Acid; Immunohistochemistry; Motor Neurons; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Receptors, Nicotinic; Spinal Cord | 2005 |
The Ror receptor tyrosine kinase CAM-1 is required for ACR-16-mediated synaptic transmission at the C. elegans neuromuscular junction.
Topics: Acetylcholine; Analysis of Variance; Animals; Animals, Genetically Modified; Behavior, Animal; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcium; Choline; Cholinergic Antagonists; Diagnostic Imaging; Dihydro-beta-Erythroidine; Electric Stimulation; gamma-Aminobutyric Acid; Gene Expression Regulation; In Vitro Techniques; Ion Channel Gating; Levamisole; Membrane Potentials; Microscopy, Electron, Transmission; Molecular Biology; Movement; Muscles; Mutagenesis; Mutation; Neuromuscular Junction; Neurons; Nicotine; Patch-Clamp Techniques; Receptor Protein-Tyrosine Kinases; Receptor Tyrosine Kinase-like Orphan Receptors; Receptors, Nicotinic; RNA, Small Interfering; Synaptic Transmission; Synaptic Vesicles; Time Factors; Trans-Activators | 2005 |
Nicotine upregulates its own receptors through enhanced intracellular maturation.
Topics: Antibodies; Autoradiography; Binding, Competitive; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Carbachol; Cell Line; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Interactions; Fluorescent Antibody Technique; Glycosylation; Humans; Immunoprecipitation; Intracellular Space; Membrane Potentials; Models, Biological; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Protein Binding; Protein Subunits; Pyridines; Receptors, Nicotinic; Time Factors; Transfection; Tritium; Up-Regulation | 2005 |
The effects of DHBE and MLA on nicotine-induced enhancement of contextual fear conditioning in C57BL/6 mice.
Topics: Aconitine; Animals; Association Learning; Brain; Conditioning, Classical; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electroshock; Fear; Male; Mice; Nicotine; Receptors, Nicotinic | 2006 |
Effects of alpha4beta2 and alpha7 nicotinic acetylcholine receptor antagonists on place aversion induced by naloxone in single-dose morphine-treated rats.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Conditioning, Operant; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2005 |
Nicotine-induced switch in the nicotinic cholinergic mechanisms of facilitation of long-term potentiation induction.
Topics: Acetylcholinesterase; Aconitine; Animals; Animals, Newborn; Antibodies, Monoclonal; Cholinergic Fibers; Denervation; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; Immunotoxins; In Vitro Techniques; Long-Term Potentiation; N-Glycosyl Hydrolases; Neural Inhibition; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Propanolamines; Quinoxalines; Rats; Receptors, Nicotinic; Ribosome Inactivating Proteins, Type 1; Saporins; Valine | 2005 |
Nicotine self-administration acutely activates brain reward systems and induces a long-lasting increase in reward sensitivity.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain; Dihydro-beta-Erythroidine; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Reward; Self Administration; Substance Withdrawal Syndrome; Time Factors | 2006 |
Indirect modulation by alpha7 nicotinic acetylcholine receptors of noradrenaline release in rat hippocampal slices: interaction with glutamate and GABA systems and effect of nicotine withdrawal.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bacterial Toxins; Biological Transport; Conotoxins; Cyanobacteria Toxins; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Marine Toxins; Microcystins; Neurons; Nicotine; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Nicotinic; Substance Withdrawal Syndrome; Tetrodotoxin; Tropanes | 2006 |
In vitro regulation of serotonin transporter activity by protein kinase A and nicotinic acetylcholine receptors in the prefrontal cortex of rats.
Topics: Animals; Atropine; Carbachol; Cholinergic Agonists; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Mecamylamine; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex; Protein Kinase Inhibitors; Rats; Receptors, Nicotinic; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptosomes; Thionucleotides; Time Factors; Tritium | 2006 |
Activation of orexin neurons by acute nicotine.
Topics: Animals; Dihydro-beta-Erythroidine; Ganglionic Stimulants; Hypothalamus; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Mecamylamine; Neurons; Neuropeptides; Nicotine; Nicotinic Antagonists; Orexins; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley | 2006 |
Reparatory effects of nicotine on NMDA receptor-mediated synaptic plasticity in the hippocampal CA1 region of chronically lead-exposed rats.
Topics: Aconitine; Animals; Central Nervous System Stimulants; Child; Dihydro-beta-Erythroidine; Female; Hippocampus; Humans; Lead Poisoning, Nervous System; Long-Term Potentiation; Male; Neuronal Plasticity; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pentanoic Acids; Picrotoxin; Random Allocation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Synaptic Transmission | 2006 |
Blockade of nicotinic acetylcholine or dopamine D1-like receptors in the central nucleus of the amygdala or the bed nucleus of the stria terminalis does not precipitate nicotine withdrawal in nicotine-dependent rats.
Topics: Amygdala; Analysis of Variance; Animals; Behavior, Animal; Benzazepines; Dihydro-beta-Erythroidine; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Nicotine; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Nicotinic; Septal Nuclei; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2006 |
Nicotine reverses consolidated long-term potentiation in the hippocampal CA1 region.
Topics: Aconitine; Analysis of Variance; Animals; Dihydro-beta-Erythroidine; Dose-Response Relationship, Radiation; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Ethers, Cyclic; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Okadaic Acid; Oxazoles; Rats; Rats, Sprague-Dawley | 2006 |
Untranslated region-dependent exclusive expression of high-sensitivity subforms of alpha4beta2 and alpha3beta2 nicotinic acetylcholine receptors.
Topics: 5' Untranslated Regions; Acetylcholine; Aconitine; Animals; Chlorisondamine; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Estradiol; Female; Ferrets; Gene Expression; Membrane Potentials; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oocytes; Protein Isoforms; Protein Subunits; Receptors, Nicotinic; Tubocurarine; Xenopus laevis | 2006 |
Reinforcing effects of nicotine microinjections into the ventral tegmental area of mice: dependence on cholinergic nicotinic and dopaminergic D1 receptors.
Topics: Animals; Behavior, Animal; Benzazepines; Dihydro-beta-Erythroidine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Male; Maze Learning; Mice; Mice, Inbred C57BL; Microinjections; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Reaction Time; Receptors, Dopamine D1; Receptors, Nicotinic; Reinforcement, Psychology; Self Administration; Spatial Behavior; Ventral Tegmental Area | 2006 |
Nicotine inhibits apoptosis induced by chemotherapeutic drugs by up-regulating XIAP and survivin.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chromatin Immunoprecipitation; Cisplatin; Deoxycytidine; Dihydro-beta-Erythroidine; Drug Resistance, Neoplasm; Gemcitabine; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Microtubule-Associated Proteins; Neoplasm Proteins; Nicotine; Paclitaxel; Promoter Regions, Genetic; Receptors, Nicotinic; Retinoblastoma Protein; Survivin; Up-Regulation; X-Linked Inhibitor of Apoptosis Protein | 2006 |
Heteromeric nicotinic acetylcholine-dopamine autoreceptor complexes modulate striatal dopamine release.
Topics: Animals; Blotting, Western; Cell Line; Corpus Striatum; Dihydro-beta-Erythroidine; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression; Humans; Immunoprecipitation; Male; Microdialysis; Nicotine; Nicotinic Agonists; Presynaptic Terminals; Quinpirole; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Nicotinic; Transfection | 2007 |
Ventral hippocampal alpha7 and alpha4beta2 nicotinic receptor blockade and clozapine effects on memory in female rats.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Antipsychotic Agents; Clozapine; Dihydro-beta-Erythroidine; Female; Hippocampus; Maze Learning; Memory; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2006 |
Evaluation of the role of nicotinic acetylcholine receptor subtypes and cannabinoid system in the discriminative stimulus effects of nicotine in rats.
Topics: Aconitine; Animals; Arachidonic Acids; Azetidines; Benzamides; Benzoxazines; Camphanes; Cannabinoid Receptor Antagonists; Carbamates; Cyclohexanols; Dihydro-beta-Erythroidine; Discrimination Learning; Dose-Response Relationship, Drug; Drug Synergism; Endocannabinoids; Male; Mecamylamine; Morpholines; Naphthalenes; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Polyunsaturated Alkamides; Pyrazoles; Pyridines; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Nicotinic | 2006 |
Alpha4beta2 nicotinic receptor stimulation contributes to the effects of nicotine in the DBA/2 mouse model of sensory gating.
Topics: Animals; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Evoked Potentials, Auditory; Hippocampus; Mecamylamine; Mental Processes; Mice; Mice, Inbred DBA; Nicotine; Receptors, Nicotinic; Schizophrenia | 2006 |
Contribution of valine 7' of TMD2 to gating of neuronal alpha3 receptor subtypes.
Topics: Acetylcholine; Aconitine; Animals; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Ion Channel Gating; Membrane Potentials; Mutagenesis; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Rats; Receptors, Nicotinic; Time Factors; Valine; Xenopus laevis | 2006 |
Repeated intracerebroventricular infusion of nicotine prevents kainate-induced neurotoxicity by activating the alpha7 nicotinic acetylcholine receptor.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Dihydro-beta-Erythroidine; DNA; Hippocampus; Injections, Intraventricular; Kainic Acid; Kindling, Neurologic; Male; Mecamylamine; Neuroprotective Agents; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Seizures; Transcription Factor AP-1 | 2007 |
Chronic nicotine exposure affects the normal operation of hippocampal circuits.
Topics: Animals; Dihydro-beta-Erythroidine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Nerve Block; Nerve Net; Nicotine; Nicotinic Agonists; Picrotoxin; Rats; Rats, Sprague-Dawley | 2007 |
Behavioral cross-tolerance between repeated intracerebellar nicotine and acute Delta(9)-tetrahydrocannabinol-induced cerebellar ataxia: role of cerebellar nitric oxide.
Topics: Animals; Cerebellar Ataxia; Cerebellum; Dihydro-beta-Erythroidine; Dronabinol; Drug Tolerance; Hexamethonium; Male; Mice; Nicotine; Nitric Oxide | 2007 |
Beta2 subunit containing acetylcholine receptors mediate nicotine withdrawal deficits in the acquisition of contextual fear conditioning.
Topics: Acoustic Stimulation; Animals; Conditioning, Classical; Cues; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Environment; Fear; Female; Infusion Pumps, Implantable; Injections, Subcutaneous; Learning; Male; Mice; Mice, Inbred C57BL; Nicotine; Psychomotor Performance; Receptors, Nicotinic; Substance Withdrawal Syndrome | 2008 |
Reinforcement enhancing effect of nicotine and its attenuation by nicotinic antagonists in rats.
Topics: Aconitine; Analysis of Variance; Animals; Conditioning, Operant; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Infusion Pumps; Infusions, Intravenous; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Photic Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reinforcement Schedule; Reinforcement, Psychology; Visual Perception | 2007 |
Cell autonomy, receptor autonomy, and thermodynamics in nicotine receptor up-regulation.
Topics: Animals; Cells, Cultured; Dihydro-beta-Erythroidine; Mecamylamine; Mesencephalon; Mice; Nicotine; Receptors, Nicotinic; Thermodynamics; Up-Regulation | 2007 |
Nicotinic control of axon excitability regulates thalamocortical transmission.
Topics: Acoustic Stimulation; Action Potentials; Analysis of Variance; Animals; Axons; Cerebral Cortex; Dihydro-beta-Erythroidine; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Postsynaptic Potentials; In Vitro Techniques; Mice; Neural Pathways; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Reaction Time; Receptors, Nicotinic; Synaptic Transmission; Thalamus | 2007 |
Hippocampal alpha4beta2 nicotinic acetylcholine receptor involvement in the enhancing effect of acute nicotine on contextual fear conditioning.
Topics: Aconitine; Analysis of Variance; Animals; Behavior, Animal; Conditioning, Classical; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Interactions; Fear; Female; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic | 2007 |
Alpha6-containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens.
Topics: Action Potentials; Analysis of Variance; Animals; Conotoxins; Dihydro-beta-Erythroidine; Dopamine; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neostriatum; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nucleus Accumbens; Receptors, Nicotinic | 2008 |
Spontaneous nicotine withdrawal potentiates the effects of stress in rats.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Behavior, Animal; Dihydro-beta-Erythroidine; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Reflex, Startle; Stress, Psychological; Substance Withdrawal Syndrome; Time Factors | 2008 |
Alpha4* nicotinic receptors in preBotzinger complex mediate cholinergic/nicotinic modulation of respiratory rhythm.
Topics: Animals; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Postsynaptic Potentials; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oocytes; Patch-Clamp Techniques; Periodicity; Protein Subunits; Receptors, Nicotinic; Respiration; Respiratory Center; Xenopus laevis | 2008 |
Glutamatergic contributions to nicotinic acetylcholine receptor agonist-evoked cholinergic transients in the prefrontal cortex.
Topics: Acetylcholine; Analysis of Variance; Animals; Choline; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electrochemistry; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Male; Mecamylamine; Neostigmine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex; Pyridines; Pyrrolidines; Quinoxalines; Rats; Sodium Channel Blockers; Tetrodotoxin; Valine | 2008 |
Changes in mRNA and protein levels of nicotinic acetylcholine receptors in Diazoxon exposed pC12 cells.
Topics: Animals; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Combinations; Gene Expression; Mecamylamine; Nicotine; Organophosphorus Compounds; PC12 Cells; Rats; Receptors, Nicotinic; RNA, Messenger | 2008 |
The role of alpha7 and alpha4beta2 nicotinic receptors in the nicotine-induced anxiolytic effect in zebrafish.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Dihydro-beta-Erythroidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Immobility Response, Tonic; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Swimming; Zebrafish; Zebrafish Proteins | 2008 |
Attenuation of ethanol-induced ataxia by alpha(4)beta(2) nicotinic acetylcholine receptor subtype in mouse cerebellum: a functional interaction.
Topics: Animals; Ataxia; Blotting, Western; Central Nervous System Depressants; Cerebellum; Dihydro-beta-Erythroidine; Ethanol; Male; Membranes; Mice; Microinjections; Nicotine; Nicotinic Agonists; Oligodeoxyribonucleotides; Postural Balance; Receptors, Nicotinic; Stereotaxic Techniques | 2008 |
Nicotine-induced Ca2+-myristoyl switch of neuronal Ca2+ sensor VILIP-1 in hippocampal neurons: a possible crosstalk mechanism for nicotinic receptors.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Calcium Signaling; Cell Membrane; Cells, Cultured; Dihydro-beta-Erythroidine; Hippocampus; Neurocalcin; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Protein Transport; Rats; Rats, Wistar; Receptor Cross-Talk; Receptors, Calcium-Sensing; Receptors, Nicotinic | 2009 |
Distinctive nicotinic acetylcholine receptor functional phenotypes of rat ventral tegmental area dopaminergic neurons.
Topics: Acetylcholine; Aconitine; Action Potentials; Alkaloids; Animals; Azocines; Brain; Choline; Dihydro-beta-Erythroidine; Dopamine; Dose-Response Relationship, Drug; Gene Expression; Kinetics; Mecamylamine; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Protein Subunits; Quinolizines; Rats; Rats, Wistar; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2009 |
Nicotinic acetylcholine alpha4beta2 receptor regulates the motivational effect of intracranial self stimulation behavior in the runway method.
Topics: Aconitine; Animals; Behavior, Animal; Conditioning, Operant; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electric Stimulation; Male; Medial Forebrain Bundle; Motivation; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic; Reward; Running; Self Stimulation | 2008 |
Nicotine activates and up-regulates nicotinic acetylcholine receptors in bronchial epithelial cells.
Topics: Acetylcholine; Aconitine; Age Factors; alpha7 Nicotinic Acetylcholine Receptor; Animals; Autocrine Communication; Bronchi; Cells, Cultured; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Genistein; Gestational Age; Lung; Macaca mulatta; Mecamylamine; Membrane Potentials; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phosphorylation; Protein Kinase Inhibitors; Protein Tyrosine Phosphatases; Receptors, Nicotinic; Up-Regulation; Vanadates | 2009 |
Properties of distinct ventral tegmental area synapses activated via pedunculopontine or ventral tegmental area stimulation in vitro.
Topics: Aconitine; Afferent Pathways; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bicuculline; Dihydro-beta-Erythroidine; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Pedunculopontine Tegmental Nucleus; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Nicotinic; Strontium; Synapses; Synaptic Transmission; Ventral Tegmental Area | 2009 |
Hippocampal nAChRs mediate nicotine withdrawal-related learning deficits.
Topics: Animals; Cerebral Cortex; Conditioning, Operant; Dihydro-beta-Erythroidine; Fear; Hippocampus; Learning Disabilities; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microinjections; Nicotine; Nicotinic Agonists; Receptors, Nicotinic; Substance Withdrawal Syndrome; Thalamus | 2009 |
Long-term nicotine treatment reduces cerebral cortical vasodilation mediated by alpha4beta2-like nicotinic acetylcholine receptors in rats.
Topics: Aconitine; Animals; Cerebral Cortex; Cerebrovascular Circulation; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Male; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic; Regional Blood Flow; Time Factors; Vasodilation | 2009 |
The hippocampus and cingulate cortex differentially mediate the effects of nicotine on learning versus on ethanol-induced learning deficits through different effects at nicotinic receptors.
Topics: Animals; Central Nervous System Depressants; Conditioning, Classical; Dihydro-beta-Erythroidine; Ethanol; Fear; Female; Gyrus Cinguli; Hippocampus; Learning; Learning Disabilities; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Time Factors | 2009 |
Nicotinic antagonist effects in the mediodorsal thalamic nucleus: regional heterogeneity of nicotinic receptor involvement in cognitive function.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Antipsychotic Agents; Clozapine; Cognition; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Maze Learning; Mediodorsal Thalamic Nucleus; Memory; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2009 |
Inhibitory role of cholinergic system mediated via alpha7 nicotinic acetylcholine receptor in LPS-induced neuro-inflammation.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Brain; Cytokines; Dihydro-beta-Erythroidine; Encephalitis; Gene Expression Regulation; Inflammation Mediators; Lipopolysaccharides; Neuroimmunomodulation; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oxotremorine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2010 |
Prenatal nicotine exposure alters medullary nicotinic and AMPA-mediated control of respiratory frequency in vitro.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Bungarotoxins; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; In Vitro Techniques; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Respiratory Center; Spinal Cord; Time Factors | 2009 |
The involvement of nicotinic receptor subtypes in the locomotor activity and analgesia induced by methamphetamine in mice.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; Dihydro-beta-Erythroidine; Drug Administration Schedule; Drug Interactions; Male; Methamphetamine; Mice; Motor Activity; Nicotine; Receptors, Nicotinic | 2009 |
Mecamylamine, dihydro-beta-erythroidine, and dextromethorphan block conditioned responding evoked by the conditional stimulus effects of nicotine.
Topics: Animals; Conditioning, Psychological; Dextromethorphan; Dihydro-beta-Erythroidine; Male; Mecamylamine; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2009 |
Nicotine provokes impulsive-like action by stimulating alpha4beta2 nicotinic acetylcholine receptors in the infralimbic, but not in the prelimbic cortex.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Impulsive Behavior; Infusions, Parenteral; Injections, Subcutaneous; Limbic System; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Reaction Time; Receptors, Nicotinic | 2010 |
Nicotine acts in the anterior cingulate, but not dorsal or ventral hippocampus, to reverse ethanol-induced learning impairments in the plus-maze discriminative avoidance task.
Topics: Animals; Avoidance Learning; Dihydro-beta-Erythroidine; Discrimination Learning; Dose-Response Relationship, Drug; Ethanol; Fear; Gyrus Cinguli; Hippocampus; Male; Maze Learning; Mice; Mice, Inbred C57BL; Motor Activity; Nicotine; Nicotinic Agonists | 2011 |
The nicotinic acetylcholine receptor alpha5 subunit plays a key role in attention circuitry and accuracy.
Topics: Acetylcholine; Analysis of Variance; Anesthetics, Local; Animals; Attention; Choice Behavior; Cholinergic Agents; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nerve Net; Neuropsychological Tests; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Photic Stimulation; Prefrontal Cortex; Pyramidal Cells; Reaction Time; Receptors, Nicotinic; Tetrodotoxin | 2010 |
The alpha2 adrenergic receptor antagonist idazoxan, but not the serotonin-2A receptor antagonist M100907, partially attenuated reward deficits associated with nicotine, but not amphetamine, withdrawal in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Amphetamine; Animals; Brain; Dihydro-beta-Erythroidine; Electrodes, Implanted; Fluorobenzenes; Ganglionic Stimulants; Idazoxan; Male; Nicotine; Piperidines; Rats; Rats, Wistar; Receptors, Nicotinic; Reward; Serotonin Antagonists; Substance Withdrawal Syndrome | 2010 |
Endogenous acetylcholine modulates impulsive action via alpha4beta2 nicotinic acetylcholine receptors in rats.
Topics: Acetylcholine; Aconitine; Animals; Behavior, Animal; Choice Behavior; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Impulsive Behavior; Male; Nicotine; Rats; Rats, Wistar; Reaction Time; Receptors, Nicotinic | 2010 |
Nicotine blocks the hyperpolarization-activated current Ih and severely impairs the oscillatory behavior of oriens-lacunosum moleculare interneurons.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Analysis of Variance; Animals; Biological Clocks; Cardiovascular Agents; Colforsin; Cyclic Nucleotide-Gated Cation Channels; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Hippocampus; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; In Vitro Techniques; Interneurons; Male; Mecamylamine; Mice; Mice, Transgenic; Models, Biological; Models, Molecular; Neural Inhibition; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Potassium Channels; Pyrimidines; Somatostatin | 2010 |
The role of nicotinic acetylcholine receptors in the medial prefrontal cortex and hippocampus in trace fear conditioning.
Topics: Aconitine; Analysis of Variance; Animals; Conditioning, Classical; Dihydro-beta-Erythroidine; Fear; Freezing Reaction, Cataleptic; Hippocampus; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex; Receptors, Nicotinic | 2010 |
The effects of nicotine, varenicline, and cytisine on schedule-controlled responding in mice: differences in α4β2 nicotinic receptor activation.
Topics: Alkaloids; Animals; Azocines; Benzazepines; Conditioning, Operant; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Quinolizines; Quinoxalines; Receptors, Nicotinic; Reinforcement Schedule; Smoking Cessation; Time Factors; Varenicline | 2011 |
Blocking α4β2 and α7 nicotinic acetylcholine receptors inhibits the reinstatement of morphine-induced CPP by drug priming in mice.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Cholinergic Antagonists; Conditioning, Operant; Dihydro-beta-Erythroidine; Drug Interactions; Extinction, Psychological; Male; Mice; Mice, Inbred BALB C; Morphine; Motor Activity; Narcotics; Nicotine; Nicotinic Agonists; Reaction Time; Receptors, Nicotinic; Reinforcement, Psychology; Time Factors | 2011 |
Functional nicotinic acetylcholine receptors containing α6 subunits are on GABAergic neuronal boutons adherent to ventral tegmental area dopamine neurons.
Topics: 4-Aminopyridine; Acetylcholine; Aconitine; Animals; Animals, Newborn; Bungarotoxins; Calcium; Conotoxins; Dihydro-beta-Erythroidine; Dopamine; Drug Interactions; Excitatory Amino Acid Agents; Female; GABA Agents; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Knockout; Neurons; Nicotine; Nicotinic Antagonists; Potassium Channel Blockers; Presynaptic Terminals; Protein Binding; Rats; Rats, Wistar; Receptors, Nicotinic; Synaptosomes; Ventral Tegmental Area | 2011 |
Short- and long-lasting consequences of in vivo nicotine treatment on hippocampal excitability.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Time Factors | 2011 |
Selective nicotinic receptor antagonists: effects on attention and nicotine-induced attentional enhancement.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Attention; Behavior, Animal; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Interactions; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Inbred Strains; Receptors, Nicotinic | 2011 |
Patterns of nicotinic receptor antagonism: nicotine discrimination studies.
Topics: Animals; Benzazepines; Bridged Bicyclo Compounds, Heterocyclic; Cytosine; Data Interpretation, Statistical; Dihydro-beta-Erythroidine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Varenicline | 2011 |
Nicotine's central cardiovascular actions: receptor subtypes involved and their possible physiological role in anaesthetized rats.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Anesthesia; Animals; Antidiuretic Hormone Receptor Antagonists; Cardiovascular System; Dihydro-beta-Erythroidine; Male; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2011 |
Withdrawal from chronic nicotine exposure alters dopamine signaling dynamics in the nucleus accumbens.
Topics: Animals; Dihydro-beta-Erythroidine; Dopamine; Drug Administration Schedule; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nucleus Accumbens; Self Administration; Substance Withdrawal Syndrome; Time Factors | 2012 |
Nicotinic excitatory postsynaptic potentials in hippocampal CA1 interneurons are predominantly mediated by nicotinic receptors that contain α4 and β2 subunits.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Aconitine; Animals; Biophysics; CA1 Region, Hippocampal; Channelrhodopsins; Cholinergic Fibers; Diagonal Band of Broca; Dihydro-beta-Erythroidine; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Interneurons; Light; Mice; Neural Pathways; Nicotine; Nicotinic Antagonists; Optics and Photonics; Patch-Clamp Techniques; Quinoxalines; Receptors, Nicotinic; Transduction, Genetic; Voltage-Sensitive Dye Imaging | 2011 |
Plasticity of prefrontal attention circuitry: upregulated muscarinic excitability in response to decreased nicotinic signaling following deletion of α5 or β2 subunits.
Topics: Acetylcholine; Aconitine; Age Factors; Analysis of Variance; Animals; Atropine; Dihydro-beta-Erythroidine; Intracellular Signaling Peptides and Proteins; Male; Membrane Potentials; Mice; Mice, Knockout; Neuronal Plasticity; Neurons; Neuropeptides; Neurotransmitter Agents; Nicotine; Nicotinic Antagonists; Orexins; Patch-Clamp Techniques; Prefrontal Cortex; Receptors, Muscarinic; Receptors, Nicotinic; Signal Transduction; Up-Regulation | 2011 |
Mitochondrial reactive oxygen species mediates nicotine-induced hypoxia-inducible factor-1α expression in human non-small cell lung cancer cells.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Dihydro-beta-Erythroidine; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Mecamylamine; Mitochondria; Mitogen-Activated Protein Kinase 1; Nicotine; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Receptors, Cholinergic; RNA Interference; RNA, Small Interfering; Smoking; Transcription, Genetic | 2012 |
Effects of sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, on body temperature regulation in mice and rats.
Topics: Aconitine; Animals; Azetidines; Body Temperature Regulation; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Nicotine; Nicotinic Antagonists; Pyridines; Rats; Receptors, Nicotinic | 2012 |
Nicotine-like effects of the neonicotinoid insecticides acetamiprid and imidacloprid on cerebellar neurons from neonatal rats.
Topics: Animals; Animals, Newborn; Brain; Bungarotoxins; Calcium; Cerebellum; Dihydro-beta-Erythroidine; Humans; Imidazoles; Insecticides; Mecamylamine; Neonicotinoids; Neurons; Neurotoxins; Nicotine; Nitro Compounds; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2012 |
Endogenously released ACh and exogenous nicotine differentially facilitate long-term potentiation induction in the hippocampal CA1 region of mice.
Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Animals, Newborn; Biophysics; CA1 Region, Hippocampal; Dihydro-beta-Erythroidine; Electric Stimulation; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Receptors, Nicotinic; Synaptic Potentials | 2012 |
Neuronal nicotinic receptor ligands modulate chronic nicotine-induced ethanol consumption in C57BL/6J mice.
Topics: Alcohol Drinking; Alkaloids; Animals; Azocines; Behavior, Addictive; Choice Behavior; Dihydro-beta-Erythroidine; Disease Models, Animal; Ethanol; Ligands; Lobeline; Male; Mice; Mice, Inbred C57BL; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Quinolizines; Receptors, Nicotinic; Signal Transduction | 2012 |
Nicotine enhances both excitatory and inhibitory synaptic inputs to inspiratory-activated airway vagal preganglionic neurons.
Topics: Acetylcholine; Aconitine; Animals; Animals, Newborn; Dihydro-beta-Erythroidine; Excitatory Postsynaptic Potentials; Glycine; Neostigmine; Neurons; Nicotine; Patch-Clamp Techniques; Rats; Receptors, Nicotinic; Vagus Nerve | 2013 |
Nicotine-induced enhancement of responding for conditioned reinforcement in rats: role of prior nicotine exposure and α4β2 nicotinic receptors.
Topics: Aconitine; Animals; Conditioning, Operant; Dihydro-beta-Erythroidine; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Long-Evans; Receptors, Nicotinic; Reinforcement Schedule | 2013 |
Effect of nicotine on the proliferation and differentiation of mouse induced pluripotent stem cells.
Topics: Animals; Benzylamines; Bungarotoxins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Differentiation; Cell Line; Cell Proliferation; Cells, Cultured; Dihydro-beta-Erythroidine; Induced Pluripotent Stem Cells; Mice; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Protein Kinase Inhibitors; Receptors, Nicotinic; Sulfonamides | 2012 |
Role of α7- and α4β2-nAChRs in the neuroprotective effect of nicotine in stress-induced impairment of hippocampus-dependent memory.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Dihydro-beta-Erythroidine; Disease Models, Animal; Drug Delivery Systems; Hippocampus; Male; Maze Learning; Memory Disorders; Neuroprotective Agents; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic; Stress, Psychological; Time Factors | 2013 |
Presynaptic α4β2 nicotinic acetylcholine receptors increase glutamate release and serotonin neuron excitability in the dorsal raphe nucleus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Aconitine; Animals; Animals, Newborn; Atropine; Bicuculline; Cadmium Chloride; Chelating Agents; Cholinergic Agonists; Dihydro-beta-Erythroidine; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Indoles; Male; Muscarinic Antagonists; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Physostigmine; Presynaptic Terminals; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Nicotinic; Ryanodine; Serotonergic Neurons; Serotonin; Sodium Channel Blockers; Tetrodotoxin | 2012 |
Electrophysiological and pharmacological evaluation of the nicotinic cholinergic system in chagasic rats.
Topics: Animals; Bungarotoxins; Chagas Cardiomyopathy; Dihydro-beta-Erythroidine; Disease Models, Animal; Electrocardiography; Heart; In Vitro Techniques; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Vagus Nerve | 2013 |
Beta2-containing nicotinic acetylcholine receptors mediate calcium/calmodulin-dependent protein kinase-II and synapsin I protein levels in the nucleus accumbens after nicotine withdrawal in mice.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Dihydro-beta-Erythroidine; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Antagonists; Nucleus Accumbens; Phosphoproteins; Phosphorylation; Receptors, Nicotinic; Signal Transduction; Substance Withdrawal Syndrome; Synapsins; Time Factors; Tobacco Use Disorder | 2013 |
Improvement of attentional function with antagonism of nicotinic receptors in female rats.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Attention; Attention Deficit Disorder with Hyperactivity; Dihydro-beta-Erythroidine; Dizocilpine Maleate; Female; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2013 |
Convergence of nicotine-induced and auditory-evoked neural activity activates ERK in auditory cortex.
Topics: Acoustic Stimulation; Animals; Auditory Cortex; Calbindins; Dihydro-beta-Erythroidine; Evoked Potentials, Auditory; Extracellular Signal-Regulated MAP Kinases; Mice; Neurons; Nicotine; Phosphorylation; Protein Subunits; Receptors, Nicotinic; S100 Calcium Binding Protein G; Thalamus | 2013 |
Layer-specific interference with cholinergic signaling in the prefrontal cortex by smoking concentrations of nicotine.
Topics: Acetylcholine; Action Potentials; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Animals, Newborn; Bicuculline; Calcium; Cholinesterase Inhibitors; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Galantamine; In Vitro Techniques; Mice; Mice, Inbred C57BL; Nerve Net; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Prefrontal Cortex; Quinoxalines; Receptors, Nicotinic; Signal Transduction | 2013 |
Multiple nicotine training doses in mice as a basis for differentiating the effects of smoking cessation aids.
Topics: Alkaloids; Animals; Azocines; Benzazepines; Dihydro-beta-Erythroidine; Discrimination Learning; Dose-Response Relationship, Drug; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Midazolam; Morphine; Nicotine; Nicotinic Agonists; Quinolizines; Quinoxalines; Receptors, Nicotinic; Smoking Cessation; Tobacco Use Cessation Devices; Varenicline | 2013 |
Nicotine primes the effect of cocaine on the induction of LTP in the amygdala.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amygdala; Animals; Bridged-Ring Compounds; Cocaine; Dihydro-beta-Erythroidine; Dopamine Uptake Inhibitors; Drug Synergism; Histone Deacetylase Inhibitors; Hydroxamic Acids; Long-Term Potentiation; Male; Mice; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Spiro Compounds; Time Factors; Vorinostat | 2013 |
MK-801 disrupts and nicotine augments 40 Hz auditory steady state responses in the auditory cortex of the urethane-anesthetized rat.
Topics: Acoustic Stimulation; Anesthetics, Intravenous; Animals; Auditory Cortex; Brain Waves; Dihydro-beta-Erythroidine; Dizocilpine Maleate; Evoked Potentials, Auditory; Excitatory Amino Acid Antagonists; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Urethane | 2013 |
A role for α4(non-α6)* nicotinic acetylcholine receptors in motor behavior.
Topics: Acetylcholine; Amphetamine; Animals; Behavior, Animal; Benzazepines; Corpus Striatum; Dihydro-beta-Erythroidine; Dopamine; Dopamine Agonists; Female; Gene Knock-In Techniques; Male; Mice; Mice, Knockout; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Point Mutation; Receptors, Nicotinic; Substantia Nigra; Synaptosomes | 2013 |
Flattening plasma corticosterone levels increases the prevalence of serotonergic dorsal raphe neurons inhibitory responses to nicotine in adrenalectomised rats.
Topics: Aconitine; Action Potentials; Adrenalectomy; Animals; Corticosterone; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Male; Neural Inhibition; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Wistar; Serotonergic Neurons; Serotonin; Serotonin Antagonists | 2013 |
Effects of blockade of α4β2 and α7 nicotinic acetylcholine receptors on cue-induced reinstatement of nicotine-seeking behaviour in rats.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Conditioning, Operant; Cues; Dihydro-beta-Erythroidine; Drug-Seeking Behavior; Extinction, Psychological; Food; Male; Nicotine; Nicotinic Antagonists; Rats; Receptors, Nicotinic; Reinforcement Schedule; Self Administration | 2014 |
The effects of nicotine and tobacco particulate matter on dopamine uptake in the rat brain.
Topics: Aconitine; Animals; Brain; Dihydro-beta-Erythroidine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Mecamylamine; Nicotiana; Nicotine; Nicotinic Antagonists; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Plant Extracts; Rats; Rats, Sprague-Dawley; RNA, Messenger; Smoking; Tobacco Smoke Pollution | 2014 |
Volatile anesthetic isoflurane inhibits LTP induction of hippocampal CA1 neurons through α4β2 nAChR subtype-mediated mechanisms.
Topics: Anesthetics, Inhalation; Animals; Azetidines; Bridged Bicyclo Compounds, Heterocyclic; CA1 Region, Hippocampal; Dihydro-beta-Erythroidine; Drug Interactions; Electric Stimulation; In Vitro Techniques; Isoflurane; Long-Term Potentiation; Mecamylamine; Muscarinic Agonists; Neural Pathways; Neurons; Nicotine; Nicotinic Agonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2013 |
Role of neuronal nicotinic acetylcholine receptors (nAChRs) on learning and memory in zebrafish.
Topics: Aconitine; Alkaloids; Animals; Azocines; Cholinergic Agents; Conotoxins; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Maze Learning; Mecamylamine; Memory; Muscarinic Antagonists; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Quinolizines; Receptors, Nicotinic; Scopolamine; Swimming; Zebrafish; Zebrafish Proteins | 2014 |
Modulation of HCN channels in lateral septum by nicotine.
Topics: Action Potentials; Animals; Biophysical Phenomena; Biophysics; Cyclic Nucleotide-Gated Cation Channels; Dihydro-beta-Erythroidine; Electric Stimulation; In Vitro Techniques; Mecamylamine; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Septal Nuclei | 2014 |
A potentially novel nicotinic receptor in Aplysia neuroendocrine cells.
Topics: Acetylcholine; Aconitine; Action Potentials; Animals; Aplysia; Conotoxins; Dihydro-beta-Erythroidine; Hexamethonium; Mecamylamine; Neuroendocrine Cells; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Strychnine; Transcriptome | 2014 |
Discriminative stimulus and hypothermic effects of some derivatives of the nAChR agonist epibatidine in mice.
Topics: Animals; Body Temperature; Bridged Bicyclo Compounds, Heterocyclic; Dihydro-beta-Erythroidine; Discrimination Learning; Male; Mecamylamine; Mice; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Receptors, Nicotinic | 2014 |
Contribution of α4β2 nAChR in nicotine-induced intracellular calcium response and excitability of MSDB neurons.
Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Calcium; Calcium Chelating Agents; Cholinergic Agonists; Diagonal Band of Broca; Dihydro-beta-Erythroidine; Egtazic Acid; Male; Membrane Potentials; Mice, Inbred BALB C; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Receptors, Nicotinic; Tissue Culture Techniques | 2014 |
Anxiolytic-like and anxiogenic-like effects of nicotine are regulated via diverse action at β2*nicotinic acetylcholine receptors.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Azetidines; Behavior, Animal; Dihydro-beta-Erythroidine; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Receptors, Nicotinic | 2015 |
Functional Upregulation of α4* Nicotinic Acetylcholine Receptors in VTA GABAergic Neurons Increases Sensitivity to Nicotine Reward.
Topics: Action Potentials; Animals; Bacterial Proteins; Calbindin 2; Calbindins; Conditioning, Operant; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; GABAergic Neurons; Glutamate Decarboxylase; Luminescent Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nicotine; Nicotinic Agonists; Proto-Oncogene Proteins c-fos; Receptors, Nicotinic; Reward; Tyrosine 3-Monooxygenase; Up-Regulation; Ventral Tegmental Area | 2015 |
Modulation of aggressive behavior in mice by nicotinic receptor subtypes.
Topics: Aconitine; Aggression; Animals; Behavior, Animal; Dihydro-beta-Erythroidine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic | 2015 |
Comparison of effects produced by nicotine and the α4β2-selective agonist 5-I-A-85380 on intracranial self-stimulation in rats.
Topics: Animals; Azetidines; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Tolerance; Male; Mecamylamine; Medial Forebrain Bundle; Nicotine; Nicotinic Agonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Self Stimulation | 2016 |
Differential discriminative-stimulus effects of cigarette smoke condensate and nicotine in nicotine-discriminating rats.
Topics: Aconitine; Animals; Dihydro-beta-Erythroidine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Smoking; Time Factors | 2016 |
α3β4 nicotinic receptors in the medial habenula and substance P transmission in the interpeduncular nucleus modulate nicotine sensitization.
Topics: Analysis of Variance; Animals; Benzylamines; Bridged Bicyclo Compounds, Heterocyclic; Cholinergic Antagonists; Chromatography, High Pressure Liquid; Dihydro-beta-Erythroidine; Dopamine; Dose-Response Relationship, Drug; Female; Interpeduncular Nucleus; Microdialysis; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Signal Transduction; Substance P | 2017 |
Nicotine-Induced Effects on Nicotinic Acetylcholine Receptors (nAChRs), Ca2+ and Brain-Derived Neurotrophic Factor (BDNF) in STC-1 Cells.
Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium; Cell Line; Dihydro-beta-Erythroidine; Enterochromaffin Cells; Enteroendocrine Cells; Gene Expression Regulation; Intestinal Mucosa; Mecamylamine; Mice; Nicotine; Receptors, G-Protein-Coupled; Receptors, Nicotinic; RNA, Messenger | 2016 |
The contribution of α4β2 and non-α4β2 nicotinic acetylcholine receptors to the discriminative stimulus effects of nicotine and varenicline in mice.
Topics: Aconitine; Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Animals; Azocines; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Dihydro-beta-Erythroidine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Hypnotics and Sedatives; Ibogaine; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Midazolam; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Quinolizines; Receptors, Nicotinic; Varenicline | 2017 |
Varenicline provokes impulsive action by stimulating α4β2 nicotinic acetylcholine receptors in the infralimbic cortex in a nicotine exposure status-dependent manner.
Topics: Administration, Oral; Animals; Appetite; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Interactions; Hypodermoclysis; Impulsive Behavior; Limbic Lobe; Male; Microinjections; Nicotine; Nicotinic Agonists; Rats; Receptors, Nicotinic; Varenicline | 2017 |
Nicotinic activity depresses synaptic potentiation in layer V pyramidal neurons of mouse insular cortex.
Topics: Acetylcholine; Animals; Animals, Newborn; Bicuculline; Cerebral Cortex; Cholinergic Agents; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; Female; GABA-A Receptor Antagonists; Lysine; Male; Mice; Mice, Inbred C57BL; Neural Inhibition; Nicotine; Pyramidal Cells; Quinoxalines; Synaptic Potentials; Valine | 2017 |
A behavioral economic analysis of the value-enhancing effects of nicotine and varenicline and the role of nicotinic acetylcholine receptors in male and female rats.
Topics: Animals; Conditioning, Operant; Cues; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Economics, Behavioral; Female; Locomotion; Male; Nicotine; Nicotinic Agonists; Photic Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reinforcement, Psychology; Sex Characteristics; Varenicline | 2018 |
Nicotine enhances responding for conditioned reinforcement via α4β2 nicotinic acetylcholine receptors in the ventral tegmental area, but not the nucleus accumbens or the prefrontal cortex.
Topics: Animals; Conditioning, Classical; Conditioning, Operant; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nucleus Accumbens; Prefrontal Cortex; Rats; Receptors, Nicotinic; Reinforcement, Psychology; Self Administration; Ventral Tegmental Area | 2019 |
Brainstem cholinergic pathways diminish cardiovascular and neuroinflammatory actions of endotoxemia in rats: Role of NFκB/α7/α4β2AChRs signaling.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Azetidines; Bradycardia; Bridged Bicyclo Compounds, Heterocyclic; Cholinergic Fibers; Dihydro-beta-Erythroidine; Endotoxemia; Hypotension; Infusions, Intraventricular; Lipopolysaccharides; Male; Medulla Oblongata; Neural Pathways; Neurogenic Inflammation; NF-kappa B; Nicotine; Pyridines; Quinuclidines; Rats; Receptors, Nicotinic; Signal Transduction; Solitary Nucleus; Tachycardia | 2019 |
Nicotine Induced Neurocognitive Protection and Anti-inflammation Effect by Activating α 4β 2 Nicotinic Acetylcholine Receptors in Ischemic Rats.
Topics: Animals; Dihydro-beta-Erythroidine; Inflammation; Ischemia; Male; Neurocognitive Disorders; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2020 |
Unexpected loss of sensitivity to the nicotinic acetylcholine receptor antagonist activity of mecamylamine and dihydro-β-erythroidine in nicotine-tolerant mice.
Topics: Animals; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Tolerance; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Smoking Cessation | 2020 |
Nicotine stimulates ion transport via metabotropic β4 subunit containing nicotinic ACh receptors.
Topics: Acetylcholine; Animals; Dihydro-beta-Erythroidine; Mecamylamine; Mice; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic | 2020 |
Nicotine Enhances Object Recognition Memory via Stimulating α4β2 and α7 Nicotinic Acetylcholine Receptors in the Medial Prefrontal Cortex of Mice.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Dihydro-beta-Erythroidine; Male; Mecamylamine; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex; Receptors, Nicotinic; Recognition, Psychology | 2021 |
Nicotine-like discriminative and aversive effects of two α4β2-selective nicotine agonists, ispronicline and metanicotine.
Topics: Animals; Behavior, Animal; Cognition; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Monitoring; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Rats; Receptors, Nicotinic | 2021 |
Nicotinic aspects of the discriminative stimulus effects of arecoline.
Topics: Animals; Arecoline; Behavior, Animal; Dihydro-beta-Erythroidine; Discrimination Learning; Mecamylamine; Muscarinic Agonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Rats; Receptors, Nicotinic; Substance-Related Disorders | 2021 |