Page last updated: 2024-08-26

nicotine and cyclosporine

nicotine has been researched along with cyclosporine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.76)18.2507
2000's12 (57.14)29.6817
2010's8 (38.10)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Tremaine, WJ1
Bell, WJ; Blaney, TJ; Francis, JM; Lindner, MD; McDermott, PE; Saydoff, JA; Sherman, SS1
Fukada, A; Inui, K; Saito, H1
Kaklamani, VG; Kaklamanis, PG; Markomichelakis, N1
Greengard, P; Hamada, M; Higashi, H; Nairn, AC; Nishi, A1
Marszalec, W; Narahashi, T; Yeh, JZ1
Beaugerie, L; Cosnes, J; Daniel, F; Marteau, P; Seksik, P1
Addy, NA; Fornasiero, EF; Picciotto, MR; Stevens, TR; Taylor, JR1
El-Gowilly, SM; El-Mas, MM; Ghazal, AR; Gohar, EY1

Reviews

1 review(s) available for nicotine and cyclosporine

ArticleYear
[Refractory proctitis].
    Gastroenterologie clinique et biologique, 2007, Volume: 31, Issue:4

    Topics: Administration, Oral; Adrenal Cortex Hormones; Algorithms; Anesthetics, Local; Antibodies, Monoclonal; Aspirin; Azathioprine; Biopsy; Cyclosporine; Drug Therapy, Combination; Escherichia coli; Forecasting; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Infliximab; Lidocaine; Methotrexate; Nicotine; Patient Compliance; Probiotics; Proctitis; Randomized Controlled Trials as Topic; Rectum; Suppositories; Time Factors

2007

Trials

1 trial(s) available for nicotine and cyclosporine

ArticleYear
Could nicotine be beneficial for Behçet's disease?
    Clinical rheumatology, 2002, Volume: 21, Issue:4

    Topics: Adult; Azathioprine; Behcet Syndrome; Colchicine; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Nicotine; Prednisolone; Prospective Studies; Smoking; Treatment Outcome

2002

Other Studies

19 other study(ies) available for nicotine and cyclosporine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Cigarette smoking should not be prescribed for the treatment of ulcerative colitis.
    Inflammatory bowel diseases, 1998, Volume: 4, Issue:4

    Topics: Adrenal Cortex Hormones; Clinical Trials as Topic; Colitis, Ulcerative; Cyclosporine; Humans; Nicotine; Recurrence; Smoking; Sulfasalazine

1998
Numerous adrenal chromaffin cell preparations fail to produce analgesic effects in the formalin test or in tests of acute pain even with nicotine stimulation.
    Pain, 2000, Volume: 88, Issue:2

    Topics: Acute Disease; Adrenal Glands; Animals; Behavior, Animal; Cattle; Cell Transplantation; Chromaffin Cells; Cyclosporine; Formaldehyde; Immunosuppressive Agents; Male; Nicotine; Nicotinic Agonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Transplantation, Heterologous

2000
Transport mechanisms of nicotine across the human intestinal epithelial cell line Caco-2.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:2

    Topics: Biological Transport; Caco-2 Cells; Chlorpheniramine; Cyclosporine; Digoxin; Diphenhydramine; Humans; Intestinal Mucosa; Kinetics; Nicotine; Recombinant Proteins; Transfection; Tritium

2002
Differential regulation of dopamine D1 and D2 signaling by nicotine in neostriatal neurons.
    Journal of neurochemistry, 2004, Volume: 90, Issue:5

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzazepines; Blotting, Western; Bungarotoxins; Cyclosporine; Dihydro-beta-Erythroidine; Dizocilpine Maleate; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Models, Neurological; Neostriatum; Nerve Tissue Proteins; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phosphoproteins; Phosphorylation; Raclopride; Receptors, Dopamine D1; Receptors, Dopamine D2; Tetrodotoxin; Threonine

2004
Desensitization of nicotine acetylcholine receptors: modulation by kinase activation and phosphatase inhibition.
    European journal of pharmacology, 2005, May-09, Volume: 514, Issue:2-3

    Topics: Acetylcholine; Animals; Cells, Cultured; Cerebral Cortex; Cyclosporine; Enzyme Activation; Enzyme Inhibitors; Membrane Potentials; Models, Biological; Neurons; Nicotine; Patch-Clamp Techniques; Phorbol Esters; Phosphoric Monoester Hydrolases; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Time Factors

2005
Role of calcineurin in nicotine-mediated locomotor sensitization.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Aug-08, Volume: 27, Issue:32

    Topics: Animals; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Male; Motor Activity; Nicotine; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area

2007
Exacerbation by nicotine of the cyclosporine A-induced impairment of beta-adrenoceptor-mediated renal vasodilation in rats.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:10

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cyclosporine; Dose-Response Relationship, Drug; Drug Synergism; Isoproterenol; Kidney; Kidney Function Tests; Male; Nicotine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Vasodilation; Vasodilator Agents

2008