nicotine has been researched along with cocaine in 512 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 128 (25.00) | 18.7374 |
| 1990's | 87 (16.99) | 18.2507 |
| 2000's | 125 (24.41) | 29.6817 |
| 2010's | 133 (25.98) | 24.3611 |
| 2020's | 39 (7.62) | 2.80 |
| Authors | Studies |
|---|---|
| Butler, DE; L'Italien, YJ; Marriott, JG; Nordin, IC; Poschel, PH; Zweisler, L | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Keserü, GM | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Jia, L; Sun, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Misra, AL; Vadlamani, NL | 1 |
| Alpern, HP; Greer, CA | 1 |
| Nedergaard, OA; Schrold, J | 1 |
| Castro, A; Malkus, H | 1 |
| Braude, MC; Husain, S; Larsen, FF; Pryor, GT | 1 |
| Gulati, OD; Shah, NS | 1 |
| Boehm, FH; Olubadewo, JO; Sastry, BV | 1 |
| Toda, N | 2 |
| Chernigovsky, VN | 1 |
| Bowman, ER; Chang, RS; McKennis, H; Wilson, KL | 1 |
| Forman, R; Graham, K; Klein, J; Koren, G; Phan, MK | 1 |
| Beeker, K; Pennington, S; Smith, C | 1 |
| Balabanova, S; Parsche, F; Pirsig, W | 2 |
| Jones, RT | 1 |
| Cox, BM; Izenwasser, S | 1 |
| Giles, MK; Horger, BA; Schenk, S | 1 |
| Bauco, P; Carlezon, WA; Trojniar, W; Wise, RA | 1 |
| Marks, MJ; Smolen, A | 1 |
| Horger, BA; Schenk, S; Snow, S | 1 |
| Fung, YK; Krueger, RJ; Lin, CM | 1 |
| Cohen, C; Henningfield, JE; Slade, JD | 1 |
| Coen, KM; Corrigall, WA | 2 |
| Barnes, NM; Costall, B; Kelly, ME; Naylor, RJ; Onaivi, ES | 1 |
| Cox, BM; Izenwasser, S; Jacocks, HM; Rosenberger, JG | 1 |
| Costall, B; Jones, BJ; Kelly, ME; Naylor, RJ; Onaivi, ES; Tyers, MB | 1 |
| Leonard-Green, T; Mohs, ME; Watson, RR | 1 |
| Bennett, FW | 1 |
| Bozarth, MA; Murray, A; Wise, RA | 1 |
| Costall, B; Kelly, ME; Naylor, RJ; Onaivi, ES | 2 |
| Amass, L; Benedikt, R; Lukas, SE; Mendelson, JH | 1 |
| Bendayan, R; Busto, U; Sellers, EM | 1 |
| Balfour, DJ; Vale, AL | 1 |
| Di Chiara, G; Imperato, A | 1 |
| Chiang, CN; Lee, CC | 1 |
| Debler, EA; Hashim, A; Lajtha, A; Sershen, H | 1 |
| Roy-Byrne, PP; Uhde, TW | 1 |
| Broussolle, EP; Fanelli, RJ; Jaffe, JH; London, ED; Weissman, AD; Wilkerson, G | 1 |
| Glowa, JR | 1 |
| de la Garza, R; Johanson, CE | 2 |
| de Smet, PA | 1 |
| Balster, RL; Slifer, BL | 1 |
| Cone, EJ; Goldberg, SR; Prada, JA; Risner, ME | 1 |
| Krstić, MK | 4 |
| Blue, JA | 1 |
| Westfall, TC | 1 |
| Borzelleca, JF; Bowman, ER; Kim, KS; McKennis, H | 1 |
| Trendelenburg, U | 1 |
| Gascon, AL; Walaszek, EJ | 1 |
| Ames, A; Pollen, DA | 1 |
| Marlow, HF | 1 |
| Bevan, JA | 1 |
| Kuchii, M; Miyahara, JT; Shibata, S | 1 |
| Nedergaard, OA | 1 |
| Ulrich, K | 1 |
| Bennett, A; Whitney, B | 1 |
| Akubue, PI | 3 |
| Dhalla, NS | 1 |
| Fisher, PA; Luduena, FP | 1 |
| Gokhale, SD; Gulati, OD; Panchal, DI | 1 |
| Funasaka, T | 2 |
| Buckley, GA; Wheater, LE | 1 |
| Bhagat, B; Friedman, E | 1 |
| Kretzschmar, R; Meyer, HJ; Teschendorf, HJ; Zöllner, B | 1 |
| Slivko, SF | 1 |
| Ishida, Y; Moritoki, H | 1 |
| Rikimaru, A; Suzuki, T | 1 |
| Higgins, TN; Taylor, JD | 1 |
| Kubota, T; Nakazawa, M; Sasaki, T | 1 |
| Araki, H | 1 |
| Kitano, T | 1 |
| Brasted, M; Westfall, TC | 2 |
| Bartlet, AL | 1 |
| Kuchii, M; Mori, J; Shibata, S | 1 |
| Taylor, WJ | 1 |
| Deshpande, VR; Jayaswal, CL; Sharma, ML | 1 |
| Bevan, JA; Su, C | 2 |
| Goldenberg, MM | 4 |
| Ueda, S | 1 |
| Ito, T; Morita, M; Nakamura, E; Sugimoto, J | 1 |
| Fujimoto, K | 1 |
| Gorosito, M; Sabelli, HC | 1 |
| Ito, T; Morita, M; Sugimoto, J | 1 |
| Marshall, RJ | 1 |
| Brown, BR; Crout, JR | 1 |
| Priest, WC; Sabelli, HC | 1 |
| Bass, P; Hug, CC; Schmiege, SK; Weisbrodt, NW | 1 |
| Fujiwara, M; Hattori, K; Mori, J; Sakurai, I; Shibata, S | 1 |
| Blattner, R; Ziegler, E | 1 |
| Nishino, K; Taga, F; Takagi, K; Takayanagi, I | 1 |
| Tewari, SN | 1 |
| Long, JP; Wong, S | 1 |
| Ilievski, V; Smith, ER | 1 |
| Bennett, A; Fleshler, B | 1 |
| Mori, Y; Ogura, Y; Watanabe, Y | 1 |
| Bruzzese, T; Casadio, S; Coppi, G; Pala, G; Turba, C | 1 |
| Botting, JH; Turmer, AD | 1 |
| Ng, KK | 1 |
| Bhagat, B; Bovell, G; Robinson, IM | 1 |
| Burks, TF; Long, JP | 1 |
| Bevan, JA; Verity, MA | 1 |
| Kirshner, N; Sage, HJ; Smith, WJ | 1 |
| Lajtha, A; Reith, ME; Sershen, H | 1 |
| Cone, EJ; Goldberg, SR; Gorodetzky, CW; Herling, S; Risner, ME; Shannon, HE; Vaupel, DB | 1 |
| Dahl, AR; Hadley, WM | 1 |
| Ceña, V; Garcia, AG; Kirpekar, SM; Nicolas, GP; Sanchez-Garcia, P | 1 |
| Kigoshi, S; Muramatsu, I; Oshita, M | 1 |
| Garcha, HS; Kumar, R; Pratt, JA; Stolerman, IP | 1 |
| Singer, G; Wallace, M | 1 |
| Khodzhagel'diev, T | 1 |
| Garza, RD; Johanson, CE | 1 |
| Goldberg, SR; Henningfield, JE; Risner, ME; Spealman, RD | 1 |
| Ator, NA; Griffiths, RR | 1 |
| Emley, GS; Hutchinson, RR | 1 |
| Ceña, V; García, AG; Montiel, C; Sánchez-García, P | 1 |
| Bigelow, GE; Brady, JV; Griffiths, RR | 1 |
| Gardner, ML; Goldberg, SR | 1 |
| Goldberg, SR; Risner, ME | 1 |
| Goldberg, SR; Spealman, RD | 1 |
| Babovic-Vuksanovic, D; Heidbreder, CA; Shippenberg, TS; Shoaib, M | 1 |
| Abood, LG; Carroll, FI; Lerner-Marmarosh, N | 1 |
| Koren, G | 1 |
| Evenden, JL; Jennings, C; Oliver, L; Turpin, M | 1 |
| Balfour, DJ; Benwell, ME; Lucchi, HM | 1 |
| Klein, J; Koren, G; Lewis, D; Papageorgiou, A; Potter, S; Stack, DM; Stott, W; Valiante, G; Zelazo, PR | 1 |
| Horger, BA; Schenk, S; Valadez, A; Wellman, PJ | 1 |
| Adamson, KL; Coen, KM; Corrigall, WA | 1 |
| Ager, JW; Angelilli, ML; Delaney-Black, V; Fischer, H; Rubinstein, M; Sokol, RJ | 1 |
| Deng, ZH; Dong, ZQ; Liu, DL | 1 |
| Drucker, E; Markowitz, M; Neuspiel, DR | 1 |
| Brothwell, D; Spigelman, M | 1 |
| Moore, N | 1 |
| Dickson, PH; Lind, A; Makoid, M; Nipper, HC; Studts, P; Therkildsen, D | 1 |
| Schenk, S; Valadez, A | 1 |
| Eliopoulos, C; Forman, R; Klein, J; Koren, G | 1 |
| Hertting, G | 1 |
| Schäfer, T | 1 |
| Björn, LO | 1 |
| Bisset, NG; Zenk, MH | 1 |
| McIntosh, ND | 1 |
| Beardsley, PM; Chiamulera, C; Tessari, M; Valerio, E | 1 |
| Löhrs, U; Nerlich, AG; Parsche, F; Schramel, P; Wiest, I | 1 |
| Giacobini, E; Lippiello, P; Summers, KL; Verhulst, S | 1 |
| Kaminer, Y | 1 |
| Koob, GF | 1 |
| White, NM | 1 |
| Nadis, S | 1 |
| O'Brien, CP | 1 |
| Heidbreder, C; Shippenberg, TS; Shoaib, M | 1 |
| Chiamulera, C; Hooft van Huijsduijnen, R; Pagliusi, SR; Pich, EM; Talabot-Ayer, D; Tessari, M | 1 |
| Chen, K; Grant, B; Kandel, D; Kessler, RC; Warner, LA | 1 |
| Baumann, MH; Goldberg, SR; Rothman, RB; Schindler, CW; Shoaib, M | 1 |
| Kuhlman, G; Mosner, A; Roehm, C; Vogel, WH | 1 |
| Cashman, JR | 1 |
| Belknap, JK; Collins, A; Crabbe, JC; Crawley, JN; Frankel, W; Henderson, N; Hitzemann, RJ; Maxson, SC; Miner, LL; Paylor, R; Silva, AJ; Wehner, JM; Wynshaw-Boris, A | 1 |
| Fibiger, HC; O'Laughlin, IA; Zernig, G | 1 |
| Changeux, JP; Fuxe, K; Léna, C; Marubio, LM; Picciotto, MR; Pich, EM; Rimondini, R; Zoli, M | 1 |
| Besson, MJ; Mathieu-Kia, AM | 1 |
| Berger, SP; Delucchi, KL; Hall, SM; Mickalian, JD; Reid, MS | 1 |
| Childress, AR; Ehrman, R; O'Brien, CP; Robbins, SJ | 1 |
| Slotkin, TA | 1 |
| Garcia, MM; Harlan, RE | 1 |
| Craft, RM; Milholland, RB | 1 |
| Hagan, J; Hatcher, JP; Lewis, VA; Reavill, C; Sanger, GJ | 1 |
| Garrett, BE; Griffiths, RR; Jones, HE | 1 |
| Gasior, M; Goldberg, SR; Jaszyna, M; Shoaib, M; Yasar, S | 2 |
| Clarke, PB; Louis, M | 1 |
| Nakamura, T; Oguri, K; Yamada, H | 1 |
| Itzhak, Y; Martin, JL | 1 |
| D'Souza, DC; Krystal, JH; Madonick, S; Petrakis, IL | 1 |
| Behnke, M; Eyler, FD | 1 |
| Mariathasan, EA; Stolerman, IP; White, JA | 1 |
| Carroll, FI; Damaj, MI; Martin, BR; Slemmer, JE | 1 |
| Ruth, JA; Stout, PR | 1 |
| Benuck, M; Hashim, A; Lajtha, A; Sershen, H; Sziraki, I | 1 |
| Carroll, ME; Lynch, WJ | 1 |
| Chen, A; Cumming, P; Dagher, A; Deep, P; Gjedde, A; Kapczinski, F; Reutens, D; Wong, DF; Yokoi, F | 1 |
| Kelley, BM; Middaugh, LD | 1 |
| Balaban-Gil, K; Rosenberg, M; Walker, A | 1 |
| Allen, D; Benuck, M; Cooper, TB; Hashim, A; Lajtha, A; Lipovac, M; Sershen, H; Sziráki, I | 1 |
| Changeux, JP; Epping-Jordan, MP; Picciotto, MR; Pich, EM | 1 |
| Partridge, B; Schenk, S | 1 |
| Costa, E; Javaid, JI; Lecca, D; Shim, I | 1 |
| Bainton, RJ; Heberlein, U; Moore, MS; Neckameyer, WS; Singh, CM; Tsai, LT | 1 |
| Bermel, RA; Brodie, JD; Dewey, SL; Gerasimov, MR; Schiffer, WK | 1 |
| Barber, DJ; Desai, RI; Terry, P | 2 |
| Kastellakis, A; Nomikos, G; Panagis, G; Spyraki, C | 1 |
| Derewlany, LO; Knie, B; Koren, G; Pastrakuljic, A | 1 |
| Dempsey, DA; Ferriero, DM; Good, W; Hajnal, BL; Jacobson, SN; Jones, RT; Partridge, JC | 1 |
| Cefilli, D; Grisso, JA; Markovic, N; Ness, RB; Shaw, LM; Stahmer, S | 1 |
| Carboni, E; Di Chiara, G; Rolando, MT; Silvagni, A | 1 |
| Dewey, SL; Franceschi, M; Gerasimov, MR; Rice, O; Schiffer, WK; Volkow, ND | 1 |
| Gasior, M; Goldberg, SR; Jaszyna, M; Peters, J | 1 |
| Anstrom, K; Azarov, A; Chang, JY; Janak, P; Woodward, DJ | 1 |
| Böhme, GA; Cossu, G; Fattore, L; Fratta, W; Imperato, A; Ledent, C; Parmentier, M | 1 |
| Caldarone, BJ; Changeux, JP; Elsworth, JD; George, TP; Picciotto, MR; Roth, RH; Weathers-Lowin, A; Zachariou, V | 1 |
| Adler, LE; Amass, L; Cawthra, E; Freedman, R; Hoffer, M; Nagamoto, HT; Olincy, A | 1 |
| Breitinger, HG; Geetha, N; Hess, GP | 1 |
| Billie, MD; Jain, AC; Mehta, MC | 1 |
| Berrettini, WH; Dadmarz, M; Ferraro, T; Golden, G; Todte, K; Tselis, N; Vogel, WH | 1 |
| Claffey, DJ; Ruth, JA; Stout, PR | 1 |
| Adamson, KL; Coen, KM; Corrigall, WA; Zhang, J | 1 |
| Hodge, CW; Koenig, HN; Nannini, MA; Olive, MF | 1 |
| Belluzzi, JD; Manzardo, AM; Stein, L | 1 |
| Adamson, L; Coen, KM; Corrigall, WA; Zhang, J | 1 |
| Ashby, CR; Dewey, SL; Gardner, EL; Gerasimov, MR; Lennon, IC; Paul, M; Taylor, SJ | 1 |
| Gutlerner, JL; Jones, S | 1 |
| De Vries, TJ; Schoffelmeer, AN; van de Ven, HW; Vanderschuren, LJ; Wardeh, G | 1 |
| Hashim, A; Lajtha, A; Sershen, H; Sziráki, I | 1 |
| Bechtholt, AJ; Mark, GP | 1 |
| Ellison, G | 1 |
| Berry, K; Riordan, M; Rylance, G | 1 |
| Cascio, MG; Di Marzo, V; Fernández-Ruiz, J; Fezza, F; González, S; Ramos, JA | 1 |
| Heberlein, U; Wolf, FW | 1 |
| McGeehan, AJ; Olive, MF | 1 |
| Desai, RI; Terry, P | 1 |
| Marr, L; Ressman, K; Sobrian, SK | 1 |
| Friedman, H; Klein, TW; Newton, C | 1 |
| Bernardi, G; Bonci, A; Grillner, P; Mercuri, NB | 1 |
| Collu, M; Fadda, P; Fratta, W; Fresu, A; Scherma, M | 1 |
| Goletiani, NV; Jaszyna-Gasior, M; Mello, NK; Mendelson, JH; Mutschler, NH; Sholar, MB; Siegel, AJ | 1 |
| Collins, G; Keyler, DE; LeSage, MG; Pentel, PR | 1 |
| Camí, J; Farré, M | 1 |
| Li, M; McMillan, DE | 1 |
| GOMEZ ALONSO DE LA SIERRA, B | 1 |
| GOMEZ ALONSO DE LA SIERRA, B; JONES, A; TRENDELENBURG, U | 1 |
| JONES, A | 1 |
| HELLMANN, K | 1 |
| KEY, BJ; MARLEY, E | 1 |
| RANG, HP | 1 |
| GOKHALE, SD; GULATI, OD; JOSHI, NY | 1 |
| SCHMIDT, HA; SPAETH, M | 1 |
| ELLIS, S; PERLMUTTER, JF; SWAINE, CR | 1 |
| MILOSEVIC, MP | 1 |
| Girlanda, E; Heidbreder, CA; Lennon, M; Mugnaini, M; Sartori, I; Varnier, G; Wildish, GA; Zanetti, L; Zocchi, A | 1 |
| Cadoni, C; Di Chiara, G; Solinas, M; Valentini, V | 1 |
| Boutrel, B; Gasparini, F; Harrison, AA; Kenny, PJ; Koob, GF; Markou, A; Paterson, NE; Semenova, S; Skoubis, PD | 1 |
| Markou, A; Paterson, NE | 2 |
| JULLIEN, A; RIPPLINGER, J | 1 |
| MACHEBOEUF, M; MUNIER, R | 1 |
| Collins, SL; Izenwasser, S | 1 |
| Caboche, J; Girault, JA; Hervé, D; Pagès, C; Valjent, E | 1 |
| Crooks, PA; Dwoskin, LP; Grinevich, VP; Miller, DK; Norrholm, SD; Zheng, G | 1 |
| Dohi, T; Kitayama, S; Kozai, K; Kumagai, K; Lin, Z; Mitsuhata, C; Morioka, N; Morita, K; Uhl, GR | 1 |
| Andreoli, M; Heidbreder, CA; Hutcheson, DM; Pilla, M; Tessari, M | 1 |
| Druid, H; Kronstrand, R; Nyström, I; Strandberg, J | 1 |
| Belluzzi, JD; Leslie, FM; Wang, R | 1 |
| Bryant, RI; Cunningham, ST; Dwoskin, LP; Middleton, LS; Neugebauer, NM; Zhu, J | 1 |
| Boutrel, B; Koob, GF | 1 |
| Robinson, TE; Samaha, AN | 1 |
| Bespalov, AY; Blokhina, EA; Danysz, W; Kashkin, VA; Zvartau, EE | 1 |
| Davis, BJ; McMillen, BA; Soderstrom, K; Williams, HL | 1 |
| Davis, KW; Ho, DH; Wellman, PJ | 1 |
| Blendy, JA; Cleck, JN; Kuo, YC; Walters, CL | 1 |
| Bainton, RJ; DeSalvo, M; Gaul, U; Heberlein, U; Schwabe, T; Tsai, LT | 1 |
| Arguinzoni, JK; Clarke, E; Haddad, GE; Scheer, A; Sobrian, SK | 1 |
| Sampaio, MC; Yonamine, M | 1 |
| Brown, WD | 1 |
| Allan, AM; Barsness, B; Martenson, T; Paz, R; Tanner, D | 1 |
| Ebner, N; Fischer, G; Sachs, G; Thau, K; Winklbaur, B | 1 |
| Bilfinger, TV; Cadet, P; Casares, FM; Khalill, S; Kim, JW; Kream, RM; Mantione, KJ; Singh, S; Stefano, GB; Zhu, W | 1 |
| Bronius, PF; Brueggeman, RJ; Schoffelmeer, AN; van Gaalen, MM; Vanderschuren, LJ | 1 |
| Kelsey, JE; Willmore, EJ | 1 |
| Bloom, A; Dixon, V; Garavan, H; Kaufman, J; LaGrave, K; Murphy, K; Risinger, R | 1 |
| Ahtee, L; Mijatovic, J; Piepponen, TP; Tuominen, RK; Vihavainen, T | 1 |
| Kream, RM; Mantione, K; Stefano, GB; Zhuu, W | 1 |
| Mørland, J | 1 |
| Pavarin, RM | 1 |
| Belluzzi, JD; Leslie, FM; Lotfipour, S; McQuown, SC; Villégier, AS | 1 |
| De Giovanni, N; Fucci, N; Scarlata, S | 1 |
| Galceran, MT; Huerta-Fontela, M; Ventura, F | 1 |
| Dopheide, MM; Miller, DK; Morgan, RE; Rodvelt, KR; Schachtman, TR | 1 |
| Bianchi, E; Cadet, P; Casares, FM; Esch, T; Fricchione, GL; Guarna, M; Kream, RM; Mantione, KJ; Stefano, GB; Zhu, W | 1 |
| Balducci, C; Cecinato, A | 1 |
| Bardo, MT; Bruntz, RC; Dwoskin, LP; Stairs, DJ; Zhu, J | 1 |
| Belluzzi, JD; Franke, RM; Leslie, FM | 1 |
| Chen, X; Lu, H; Zhan, CG | 1 |
| Gass, JT; Olive, MF | 1 |
| Becker, JB; Hu, M | 1 |
| Bevins, RA; Linkugel, JD; Reichel, CM | 1 |
| Barnes, C; Goldberg, SR; Justinova, Z; Le Foll, B; Wertheim, CE | 1 |
| McIntosh, JM; O'Leary, K; Parameswaran, N; Quik, M | 1 |
| Nechifor, M | 1 |
| Glick, SD; Hussain, RJ; Taraschenko, OD | 1 |
| Belluzzi, JD; Franke, RM; Leslie, FM; Park, M | 1 |
| Bertol, E; Mari, F; Politi, L | 1 |
| Bossert, JM; Crombag, HS; Koya, E; Shaham, Y | 1 |
| Barnes, C; Ferré, S; Goldberg, SR; Justinova, Z; Le Foll, B; Pappas, LA; Wertheim, CE | 1 |
| Choo, RE; Huestis, MA; Johnson, RE; Jones, HE; Kacinko, SL | 1 |
| Lubick, N | 1 |
| Ameis, K; Johnston, M; Kuhn, D; Sobrian, SK; Wright, J | 1 |
| Bevins, RA; Li, C; Wilkinson, JL | 1 |
| Allegrini, I; Balducci, C; Cecinato, A; Nervegna, G; Tagliacozzo, G | 1 |
| Kalivas, PW; Knackstedt, LA | 1 |
| Huestis, MA; Shakleya, DM | 1 |
| Bordia, T; Huang, LZ; Michael McIntosh, J; Parameswaran, N; Quik, M | 1 |
| Levitt, P; Stanwood, GD; Thompson, BL | 1 |
| Sivapalan, H | 1 |
| Hashim, A; Lajtha, A; Sershen, H | 1 |
| Freeman, KB; Woolverton, WL | 1 |
| Belluzzi, JD; Dao, JM; Leslie, FM; McQuown, SC | 1 |
| Fadda, P; Fattore, L; Fratta, W | 1 |
| High, PC; Lagasse, LL; Lester, BM; Miller-Loncar, CL; Stone, KC | 1 |
| Ware, JC | 1 |
| Mello, NK | 1 |
| Bird, MK; Lawrence, AJ | 1 |
| Civit, E; de la Torre, R; Falcón, M; Garcia-Algar, O; Joya, X; Luna, A; Pichini, S; Pujadas, M; Vall, O | 1 |
| Kovacs, K; Lajtha, A; Sershen, H | 1 |
| Bordia, T; Campos, C; McIntosh, JM; Quik, M | 1 |
| Cador, M; Caillé, S; Clemens, KJ | 1 |
| Bada, HS; Bauer, CR; Hammond, JA; LaGasse, LL; Lester, BM; Shankaran, S; Stone, KC | 1 |
| Bardo, MT; Neugebauer, NM; Stairs, DJ | 1 |
| Carta, S; Goldberg, SR; Lecca, S; Luchicchi, A; Muntoni, AL; Pillolla, G; Pistis, M; Yasar, S | 1 |
| Armario, A | 1 |
| Cadoni, C; Di Chiara, G; Fenu, S | 1 |
| Esposito, EX; Hopfinger, AJ; Shen, MY; Su, BH; Tseng, YJ | 1 |
| Bruckmann, W; De Vry, J; Rutten, K; Tzschentke, TM; Van Der Kam, EL | 1 |
| Kauer, JA; Murali, M; Niehaus, JL | 1 |
| Concheiro, M; Gray, TR; Huestis, MA; Shakleya, DM | 1 |
| Contet, C; Jarrell, H; Kenny, PJ; Markou, A; Whisler, KN | 1 |
| Griffiths, RR; Johnson, MW; Strain, EC | 1 |
| Blanco, C; Grant, BF; Hasin, DS; Lopez-Quintero, C; Okuda, M; Pérez de los Cobos, J; Wang, S | 1 |
| Hales, CA; Henehan, RM; Neugebauer, NM; Picciotto, MR | 1 |
| Balland, B; Bellone, C; Bocklisch, C; Brown, MT; Dahan, L; Deisseroth, K; Labouèbe, G; Luján, R; Lüscher, C; Mameli, M | 1 |
| Blaha, CD; Chesler, EJ; Dickson, PE; Goldowitz, D; Lester, DB; Matta, SG; Miller, MM; Mittleman, G; Rogers, TD | 1 |
| Sulzer, D | 1 |
| Anker, JJ; Carroll, ME | 1 |
| Boleda, MA; Galceran, MA; Ventura, F | 1 |
| Mello, NK; Newman, JL | 1 |
| Galceran, MT; Huerta-Fontela, M; Rosa Boleda, M; Ventura, F | 1 |
| Ben Hamida, S; Cassel, JC; de Vasconcelos, AP; Jones, BC; Mohamed, WM | 1 |
| Cauley, M; Horton, K; Johnson, M; Levin, ED; Petro, A; Rezvani, AH; Slade, S; Vendittelli, A; Wells, C; Williams, P | 1 |
| Czoty, PW; Gould, RW; Nader, MA; Nader, SH | 1 |
| Li, MD; Wang, J; Yuan, W | 1 |
| Corbett, SM; Piper, BJ | 1 |
| Volkow, ND | 1 |
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| Bade, R; Baz-Lomba, JA; Bramness, J; Castiglioni, S; Castrignanò, E; Causanilles, A; de Voogt, P; Gracia-Lor, E; Hernandez, F; Kasprzyk-Hordern, B; Kinyua, J; McCall, AK; Ort, C; Plósz, BG; Ramin, P; Reid, M; Rousis, NI; Ryu, Y; Salvatore, S; Thomas, K; van Nuijs, A | 1 |
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| Alhadeff, AL; Betley, JN; Goldstein, N; Klima, ML; Park, O; Vargas, A | 1 |
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| Alalawi, A; Aldhafiri, A; Dodu, JC; Emadzadeh, N; Soderstrom, K | 1 |
| Bai, Y; Belluzzi, JD; Cardenas, A; Chen, Y; Dwyer, JB; Franke, RM; Leslie, FM; Lotfipour, S | 1 |
| Batalla, A; Blaine, S; Brooks, S; Caparelli, EC; Ching, CRK; Chye, Y; Conrod, P; Cousijn, J; Dagher, A; Foxe, JJ; Garavan, H; Goudriaan, AE; Gutman, BA; Hester, R; Hutchison, K; Jahanshad, N; Kaag, AM; Korucuoglu, O; Li, CR; London, ED; Lorenzetti, V; Luijten, M; Mackey, S; Martin-Santos, R; Meda, SA; Momenan, R; Morales, A; Orr, C; Paulus, MP; Pearlson, G; Reneman, L; Schmaal, L; Sinha, R; Solowij, N; Stein, DJ; Stein, EA; Tang, D; Thompson, PM; Uhlmann, A; van Holst, R; Veltman, DJ; Verdejo-Garcia, A; Wiers, RW; Yücel, M | 1 |
| Barkin, CE; Blough, BE; Carroll, FI; de Moura, FB; Kohut, SJ; Mello, NK | 1 |
| Bassareo, V; Carboni, E; Carta, AR; Jadzic, D | 1 |
| Ahmadi-Soleimani, SM; Azadi, M; Azizi, H; Halliwell, RF; Pachenari, N; Rubino, T; Salmanzadeh, H | 1 |
| Cano, M; Gad, M; Green, KN; Leslie, FM; Linker, KE; Tawadrous, P; Wood, MA | 1 |
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| de Almeida, RMM; Krolow, R; Lampert, C; Noschang, C | 1 |
| Chen, L; Ru, Q; Wu, YX; Zhou, M | 1 |
| Alcaraz-Silva, J; Barberena, JJ; Budde, H; Imperatori, C; Machado, S; Murillo-Rodríguez, E; Quiroga, C; Telles-Correia, D; Yadollahpour, A; Yamamoto, T | 1 |
| Baidoo, N; Francis, T; Lapointe, T; Leri, F; Melanson, B; Winters, BD; Wolter, M | 1 |
| Collins, GT; Doyle, MR; Rice, KC; Sulima, A | 1 |
| Babigian, CJ; Sartor, GC; Wahlestedt, C; Wiedner, HJ | 1 |
| Alia-Klein, N; Allgaier, N; Cao, Z; Conrod, P; Cupertino, RB; Ekhtiari, H; Fouche, JP; Garavan, H; Goldstein, RZ; Hahn, S; Jahanshad, N; Li, CR; Lochner, C; London, ED; Luijten, M; Mackey, S; Masjoodi, S; Momenan, R; Oghabian, MA; Ottino-González, J; Roos, A; Schwab, N; Stein, DJ; Stein, EA; Thompson, PM; Uhlmann, A; Veltman, DJ; Verdejo-García, A; Zhang, S; Zhao, M; Zhong, N | 1 |
| Campbell, CI; Chi, FW; Kline-Simon, AH; Metz, VE; Palzes, VA; Sterling, SA; Weisner, CM | 1 |
| Fluyau, D; Jain, A; Kailasam, VK; Mitra, P; Pierre, CG | 1 |
| Mellos, E; Paparrigopoulos, T | 1 |
| Chang, SH; Chang, XW; Chen, Y; Li, YY; Lu, L; Muhai, JN; Shi, J; Sun, Y | 1 |
| Bastiani, MF; da Silva Moreira, IC; do Nascimento, CA; Hahn, RZ; Linden, R; Lizot, LLF; Meireles, YF; Schneider, A; Viana, MF | 1 |
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| Dong, J; Feng, Q; Guo, S; Jiang, L; Li, Q; Liu, G; Liu, L; Nie, J; Wang, Y; Wei, J; Yang, J | 1 |
| Bury, E; Cameriere, R; Cingolani, M; Ribeiro, ILA; Scendoni, R | 1 |
| Cimrmančič, B; Eleršek, T; Heath, D; Heath, E; Kocman, D; Kosjek, T; Kozlovič-Bobič, T; Kramarič Zidar, V; Krizman-Matasic, I; Laimou-Geraniou, M; Levstek, M; Lukšič, S; Mislej, V; Mišmaš, B; Prosen, H; Stražar, M; Šuštarič, A; Uranjek, N; Verovšek, T | 1 |
| Baidoo, N; Lapointe, T; Leri, F; Mitchnick, KA; Wideman, C; Winters, BD; Wolter, M | 1 |
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| Aliyeva, M; Ather, JL; Casey, DT; Chapman, DG; Daphtary, N; Irvin, CG; Janssen-Heininger, YMW; Lahue, KG; van der Velden, JL | 1 |
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76 review(s) available for nicotine and cocaine
| Article | Year |
|---|---|
Radioimmunoassays of drugs of abuse in humans: a review.
Topics: Amphetamines; Barbiturates; Body Fluids; Cocaine; Humans; Illicit Drugs; Lysergic Acid Diethylamide; Methadone; Methaqualone; Morphine; Nicotine; Pharmaceutical Preparations; Radioimmunoassay | 1977 |
Biological markers of intrauterine exposure to cocaine and cigarette smoking.
Topics: Biomarkers; Cocaine; Female; Hair; Humans; Maternal-Fetal Exchange; Nicotine; Pregnancy; Smoking | 1992 |
What have we learned from nicotine, cocaine, and marijuana about addiction?
Topics: Brain; Cannabinoids; Cocaine; Humans; Marijuana Abuse; Nicotine; Smoking; Smoking Cessation; Substance Withdrawal Syndrome; Substance-Related Disorders | 1992 |
Self-stimulation and drug reward mechanisms.
Topics: Animals; Brain; Cocaine; Humans; Nicotine; Phencyclidine; Reward; Self Stimulation; Substance-Related Disorders | 1992 |
Is nicotine more addictive than cocaine?
Topics: Animals; Cocaine; Cross-Sectional Studies; Euphoria; Humans; Incidence; Nicotine; Smoking; Substance-Related Disorders; United Kingdom | 1991 |
Nutritional effects of marijuana, heroin, cocaine, and nicotine.
Topics: Animals; Cannabis; Cocaine; Deficiency Diseases; Diet; Feeding Behavior; Heroin; Humans; Nicotine; Nutritional Status; Substance-Related Disorders | 1990 |
Clinical pharmacokinetics of non-opiate abused drugs.
Topics: Amphetamines; Anti-Anxiety Agents; Benzodiazepines; Caffeine; Cannabinoids; Cocaine; Humans; Illicit Drugs; Nicotine; Phencyclidine | 1989 |
Exogenous factors in panic disorder: clinical and research implications.
Topics: Anxiety Disorders; Caffeine; Cocaine; Diet; Ethanol; Fear; Humans; Life Change Events; Marijuana Abuse; Nicotine; Nonprescription Drugs; Pain; Panic; Physical Exertion; Sleep Deprivation; Substance-Related Disorders | 1988 |
A multidisciplinary overview of intoxicating snuff rituals in the western hemisphere.
Topics: Atropine; Bufotenin; Caffeine; Cannabis; Capsicum; Ceremonial Behavior; Chemical Phenomena; Chemistry; Cocaine; Datura stramonium; Harmine; Humans; Indians, North American; Indians, South American; N,N-Dimethyltryptamine; Nicotiana; Nicotine; Plants; Plants, Medicinal; Plants, Toxic; Psychotropic Drugs; Scopolamine; Tobacco, Smokeless | 1985 |
Second-order schedules: extended sequences of behavior controlled by brief environmental stimuli associated with drug self-administration.
Topics: Animals; Behavior, Animal; Cocaine; Drug Administration Schedule; Environment; Humans; Injections, Intramuscular; Injections, Intravenous; Macaca mulatta; Morphine; Nicotine; Rats; Saimiri; Self Administration; Substance-Related Disorders | 1981 |
Measurement of drugs in neonatal hair; a window to fetal exposure.
Topics: Cocaine; Female; Fetus; Hair; Humans; Infant, Newborn; Maternal-Fetal Exchange; Nicotine; Pregnancy; Smoking; Tobacco Smoke Pollution | 1995 |
Pharmacotherapy for adolescents with psychoactive substance use disorders.
Topics: Adolescent; Adolescent Behavior; Cocaine; Humans; Mental Disorders; Narcotics; Nicotine; Psychotropic Drugs; Substance-Related Disorders | 1995 |
Drug addiction: the yin and yang of hedonic homeostasis.
Topics: Amphetamine; Amygdala; Brain; Cocaine; Drug Tolerance; Homeostasis; Humans; Narcotics; Neuropeptides; Nicotine; Receptors, Dopamine; Reinforcement, Psychology; Substance Withdrawal Syndrome; Substance-Related Disorders | 1996 |
Addictive drugs as reinforcers: multiple partial actions on memory systems.
Topics: Amphetamines; Animals; Behavior, Animal; Brain; Cocaine; Ethanol; Hippocampus; Learning; Memory; Morphine; Nicotine; Reinforcement, Psychology; Self Administration | 1996 |
Recent developments in the pharmacotherapy of substance abuse.
Topics: Cannabis; Cocaine; Diagnosis, Dual (Psychiatry); Drug Therapy; Hallucinogens; Humans; Hypnotics and Sedatives; Nicotine; Substance-Related Disorders | 1996 |
Biocatalysts in detoxication of drugs of abuse.
Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Antibodies, Anti-Idiotypic; Cocaine; Cytochrome P-450 Enzyme System; Humans; Illicit Drugs; Inactivation, Metabolic; Nicotine; Oxygenases; RNA, Catalytic | 1997 |
Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Behavior, Animal; Cocaine; Ethanol; Genetics, Behavioral; Mice; Mice, Inbred Strains; Nicotine; Phenotype | 1997 |
Drugs of abuse and immediate-early genes in the forebrain.
Topics: Amphetamines; Animals; Caffeine; Cocaine; Dronabinol; Gene Expression Regulation; Genes, Immediate-Early; Humans; Illicit Drugs; Immediate-Early Proteins; Morphine; Nicotine; Prosencephalon; Substance-Related Disorders | 1998 |
Toward a rational pharmacotherapy of comorbid substance abuse in schizophrenic patients.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Cannabis; Central Nervous System Stimulants; Cocaine; Cognition Disorders; Dopamine; Health Care Costs; Humans; Nicotine; Schizophrenia; Schizophrenic Psychology; Substance-Related Disorders | 1999 |
Early development of infants exposed to drugs prenatally.
Topics: Alcoholism; Child Abuse; Child Development; Child, Preschool; Cocaine; Cocaine-Related Disorders; Ethanol; Female; Heroin; Heroin Dependence; Humans; Infant; Infant, Newborn; Marijuana Abuse; Methadone; Nicotine; Poverty; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Risk Factors; Smoking; Substance-Related Disorders | 1999 |
Neurodevelopmental and neurobehavioral sequelae of selected substances of abuse and psychiatric medications in utero.
Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Cannabis; Cocaine; Ethanol; Female; Humans; Infant, Newborn; Lithium; Nicotine; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Substance-Related Disorders | 1999 |
Activity patterns in mesolimbic regions in rats during operant tasks for reward.
Topics: Action Potentials; Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dopamine; Dopamine Agonists; Electrodes, Implanted; Ethanol; Haplorhini; Heroin; Limbic System; Models, Neurological; Nicotine; Nucleus Accumbens; Prefrontal Cortex; Psychomotor Performance; Rats; Reward; Species Specificity; Time Factors | 2000 |
Addictive drugs modify excitatory synaptic control of midbrain dopamine cells.
Topics: Amphetamine; Animals; Cocaine; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Ganglionic Stimulants; Humans; Mesencephalon; Nicotine; Synapses | 2002 |
Poisoning in children 5: rare and dangerous poisons.
Topics: 2-Propanol; Adrenergic beta-Antagonists; Carbon Monoxide Poisoning; Child; Cocaine; Cyanides; Digoxin; Ethylene Glycol; Humans; Hypoglycemic Agents; Insecticides; Isoniazid; Lysergic Acid Diethylamide; Methanol; N-Methyl-3,4-methylenedioxyamphetamine; Nicotine; Organophosphorus Compounds; Poisoning | 2002 |
Invertebrate models of drug abuse.
Topics: Alcoholic Intoxication; Animals; Behavior, Animal; Caenorhabditis elegans; Cocaine; Disease Models, Animal; Dopamine; Drosophila melanogaster; Drug Tolerance; Ethanol; Learning; Memory; Nicotine; Substance-Related Disorders | 2003 |
Microbial infections, immunomodulation, and drugs of abuse.
Topics: Cannabis; Cocaine; Disease Susceptibility; Ethanol; Humans; Immune Tolerance; Immunity; Infections; Narcotics; Nicotine; Substance-Related Disorders | 2003 |
The dopamine-containing neuron: maestro or simple musician in the orchestra of addiction?
Topics: Amphetamine; Animals; Cocaine; Dopamine; Humans; Mesencephalon; Models, Biological; Morphine; Narcotics; Nerve Endings; Neurons; Nicotine; Receptors, Dopamine; Substance-Related Disorders | 2003 |
Drug addiction.
Topics: Animals; Cannabinoids; Cocaine; Disease Models, Animal; Dopamine; Ethanol; Humans; Narcotics; Nicotine; Recurrence; Reinforcement, Psychology; Substance Withdrawal Syndrome; Substance-Related Disorders | 2003 |
Regulation of dopamine and MPP+ transport by catecholamine transporters.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Carrier Proteins; Catecholamine Plasma Membrane Transport Proteins; Cocaine; Dopamine; Drug Design; Humans; Membrane Transport Proteins; Nicotine | 2004 |
What keeps us awake: the neuropharmacology of stimulants and wakefulness-promoting medications.
Topics: Amphetamine; Benzhydryl Compounds; Brain; Central Nervous System Stimulants; Cocaine; Dopamine Uptake Inhibitors; Humans; Methylphenidate; Modafinil; Narcolepsy; Nicotine; Sleep; Wakefulness | 2004 |
Why does the rapid delivery of drugs to the brain promote addiction?
Topics: Animals; Biological Availability; Brain; Cocaine; Drug Delivery Systems; Expert Testimony; Humans; Nicotine; Substance-Related Disorders; Time Factors | 2005 |
The effect of medication on sleep.
Topics: Cardiovascular Agents; Central Nervous System Agents; Cocaine; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Ethanol; Humans; Nicotine; Polysomnography; Sleep | 2006 |
Substance abuse in patients with schizophrenia.
Topics: Cannabis; Cocaine; Humans; Nicotine; Schizophrenia; Substance-Related Disorders | 2006 |
[Vaccines against substance abuse].
Topics: Animals; Antibody Formation; Cocaine; Cocaine-Related Disorders; Humans; Nicotine; Smoking; Smoking Prevention; Substance-Related Disorders; Vaccination; Vaccines | 2006 |
Nicotine, alcohol and cocaine coupling to reward processes via endogenous morphine signaling: the dopamine-morphine hypothesis.
Topics: Alcohols; Animals; Cocaine; Humans; Models, Biological; Morphine; Nicotine; Reward; Signal Transduction | 2007 |
Glutamatergic substrates of drug addiction and alcoholism.
Topics: Alcoholism; Amphetamines; Animals; Cannabinoids; Cocaine; Disease Models, Animal; Extinction, Psychological; Glutamic Acid; Humans; Narcotics; Neuronal Plasticity; Nicotine; Substance-Related Disorders; Synapses; Synaptic Transmission | 2008 |
Sex differences in drug abuse.
Topics: Animals; Cocaine; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor alpha; Estrous Cycle; Ethanol; Female; Humans; Male; Models, Biological; Narcotics; Nicotine; Psychomotor Performance; Risk Factors; Sex Characteristics; Sex Chromosomes; Substance-Related Disorders | 2008 |
Magnesium in drug dependences.
Topics: Amphetamine; Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Magnesium; Models, Biological; Nicotine; Substance-Related Disorders; Tobacco Use Disorder | 2008 |
Review. Context-induced relapse to drug seeking: a review.
Topics: Animals; Behavior, Addictive; Brain; Cocaine; Conditioning, Psychological; Ethanol; Extinction, Psychological; Heroin; Humans; Neurotransmitter Agents; Nicotine; Rats; Recurrence; Self Administration; Substance-Related Disorders | 2008 |
Glutamate and reinstatement.
Topics: Animals; Behavior, Addictive; Brain; Cocaine; Ethanol; Glutamic Acid; Heroin; Humans; Nicotine; Receptors, Glutamate; Recurrence; Substance-Related Disorders; Synaptic Transmission | 2009 |
Prenatal exposure to drugs: effects on brain development and implications for policy and education.
Topics: Alcohols; Amphetamine; Antidepressive Agents; Brain; Child; Crack Cocaine; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Maternal-Fetal Exchange; Methamphetamine; Nicotine; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Substance-Related Disorders | 2009 |
Khantzian's 'self-medication hypothesis' of drug addiction and films by Martin Scorsese.
Topics: Cocaine; Dopamine Uptake Inhibitors; History, 20th Century; History, 21st Century; Humans; Hypnotics and Sedatives; Motion Pictures; Nicotine; Nicotinic Agonists; Self Medication; Substance-Related Disorders | 2009 |
Hormones, nicotine, and cocaine: clinical studies.
Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Hormones; Humans; Nicotine; Nicotinic Agonists | 2010 |
Group I metabotropic glutamate receptors: involvement in drug-seeking and drug-induced plasticity.
Topics: Alcohols; Animals; Calcium; Cocaine; Humans; Mice; Neuronal Plasticity; Nicotine; Opioid Peptides; Receptors, Metabotropic Glutamate; Substance-Related Disorders | 2009 |
Activation of the hypothalamic-pituitary-adrenal axis by addictive drugs: different pathways, common outcome.
Topics: Amphetamine; Analgesics, Opioid; Animals; Cannabinoids; Central Nervous System Agents; Cocaine; Ethanol; Humans; Hypothalamo-Hypophyseal System; Metabolic Networks and Pathways; Nicotine; Pituitary-Adrenal System; Substance-Related Disorders; Treatment Outcome | 2010 |
How addictive drugs disrupt presynaptic dopamine neurotransmission.
Topics: Amphetamines; Analgesics, Opioid; Animals; Central Nervous System Agents; Cocaine; Dopamine; Ethanol; Humans; Hypnotics and Sedatives; Models, Biological; Neural Inhibition; Neurons; Nicotine; Presynaptic Terminals; Synaptic Transmission | 2011 |
MDMA: interactions with other psychoactive drugs.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Caffeine; Cannabis; Central Nervous System Depressants; Cocaine; Drug Interactions; Ethanol; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Nicotine; Psychotropic Drugs; Substance-Related Disorders | 2011 |
Genes and pathways co-associated with the exposure to multiple drugs of abuse, including alcohol, amphetamine/methamphetamine, cocaine, marijuana, morphine, and/or nicotine: a review of proteomics analyses.
Topics: Amphetamines; Animals; Brain; Brain Chemistry; Cannabinoids; Cannabis; Cocaine; Ethanol; Gene Expression; Gene Expression Profiling; Humans; Illicit Drugs; Methamphetamine; Morphine; Nicotine; Proteomics; Substance-Related Disorders | 2011 |
Drosophila melanogaster as a model to study drug addiction.
Topics: Amphetamines; Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Drosophila melanogaster; Ethanol; Neural Pathways; Nicotine; Substance-Related Disorders; Synaptic Transmission | 2012 |
[Structural plasticity associated with drugs addiction].
Topics: Amphetamine; Animals; Brain; Cocaine; Humans; Morphine; Neuronal Plasticity; Nicotine; Reward; Substance-Related Disorders; Synapses | 2011 |
Cocaine and nicotine research illustrates a range of hypocretin mechanisms in addiction.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Humans; Hypothalamic Area, Lateral; Intracellular Signaling Peptides and Proteins; Neurons; Neuropeptides; Nicotine; Orexin Receptors; Orexins; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Substance-Related Disorders; Synaptic Transmission; Ventral Tegmental Area | 2012 |
Substance abuse, memory, and post-traumatic stress disorder.
Topics: Animals; Cocaine; Conditioning, Psychological; Ethanol; Fear; Humans; Memory; Nicotine; Stress Disorders, Post-Traumatic; Substance-Related Disorders | 2014 |
The Gateway Hypothesis of substance abuse: developmental, biological and societal perspectives.
Topics: Animals; Behavior, Animal; Cocaine; Corpus Striatum; Disease Models, Animal; Disease Progression; Dopamine Uptake Inhibitors; Ganglionic Stimulants; Humans; Nicotine; Substance-Related Disorders | 2015 |
Multigenerational and transgenerational inheritance of drug exposure: The effects of alcohol, opiates, cocaine, marijuana, and nicotine.
Topics: Alcohols; Analgesics, Opioid; Animals; Cannabis; Cocaine; Environmental Exposure; Humans; Inheritance Patterns; Nicotine; Substance-Related Disorders | 2015 |
Effects of drugs of abuse on the central neuropeptide Y system.
Topics: Amphetamines; Animals; Brain; Cocaine; Disease Models, Animal; Ethanol; Mice; Neuropeptide Y; Nicotine; Opiate Alkaloids; Rats; Receptors, Neuropeptide Y | 2016 |
Clock genes × stress × reward interactions in alcohol and substance use disorders.
Topics: Alcoholism; Animals; Central Nervous System Depressants; Circadian Clocks; Circadian Rhythm Signaling Peptides and Proteins; Cocaine; Dopamine Uptake Inhibitors; Ethanol; Gene-Environment Interaction; Humans; Hypothalamo-Hypophyseal System; Nicotine; Nicotinic Agonists; Pituitary-Adrenal System; Reward; Stress, Psychological; Substance-Related Disorders | 2015 |
The opioid receptors as targets for drug abuse medication.
Topics: Alcohol Drinking; Animals; Central Nervous System Stimulants; Cocaine; Ganglionic Stimulants; Humans; Nicotine; Receptors, Opioid; Substance-Related Disorders | 2015 |
Polysomnographic sleep disturbances in nicotine, caffeine, alcohol, cocaine, opioid, and cannabis use: A focused review.
Topics: Analgesics, Opioid; Caffeine; Cannabis; Cocaine; Ethanol; Humans; Nicotine; Polysomnography; Sleep Wake Disorders | 2015 |
Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse.
Topics: Alcoholism; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamines; Animals; Behavior, Addictive; Benzodiazepines; Brain; Cannabinoids; Cocaine; Depression; Dose-Response Relationship, Drug; Gene Expression; Hallucinogens; Humans; Illicit Drugs; Narcotics; Nerve Growth Factors; Neuroimaging; Neuronal Plasticity; Nicotine; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Substance-Related Disorders; Synaptic Transmission | 2015 |
Is immunotherapy an opportunity for effective treatment of drug addiction?
Topics: Antibodies, Monoclonal; Clinical Trials as Topic; Cocaine; Female; Heroin; Humans; Immunization, Passive; Immunotherapy; Male; Nicotine; Substance-Related Disorders; Treatment Outcome; Vaccination | 2015 |
Effects of addictive drugs on adult neural stem/progenitor cells.
Topics: Adult Stem Cells; Amphetamine; Analgesics, Opioid; Animals; Cannabinoids; Cell Proliferation; Central Nervous System Stimulants; Cocaine; Ethanol; Ganglionic Stimulants; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Neural Stem Cells; Neurogenesis; Neurotransmitter Agents; Nicotine; Substance-Related Disorders | 2016 |
Drugs of abuse and blood-brain barrier endothelial dysfunction: A focus on the role of oxidative stress.
Topics: Animals; Blood-Brain Barrier; Central Nervous System Stimulants; Cocaine; Encephalitis, Viral; HIV; HIV Infections; Humans; Methamphetamine; Nicotine; Oxidative Stress; Smoking | 2016 |
Negative Allosteric Modulators of Metabotropic Glutamate Receptors Subtype 5 in Addiction: a Therapeutic Window.
Topics: Allosteric Regulation; Animals; Cocaine; Drug-Seeking Behavior; Ethanol; Nicotine; Pyridines; Receptor, Metabotropic Glutamate 5; Self Administration; Substance-Related Disorders; Thiazoles | 2016 |
Epigenetic mechanisms associated with addiction-related behavioural effects of nicotine and/or cocaine: implication of the endocannabinoid system.
Topics: Animals; Behavior, Addictive; Cannabinoids; Cigarette Smoking; Cocaine; Cocaine-Related Disorders; DNA Methylation; Endocannabinoids; Epigenesis, Genetic; Humans; Marijuana Use; Neuronal Plasticity; Nicotine; Substance-Related Disorders | 2017 |
Noncoding RNAs in development and teratology, with focus on effects of cannabis, cocaine, nicotine, and ethanol.
Topics: Abnormalities, Drug-Induced; Animals; Cannabis; Cocaine; Congenital Abnormalities; Ethanol; Gene Regulatory Networks; Humans; Nicotine; RNA, Untranslated; Teratology | 2019 |
Adolescent drug exposure: A review of evidence for the development of persistent changes in brain function.
Topics: Adolescent; Age Factors; Amphetamine; Animals; Brain; Cannabinoids; Cocaine; Cognition; Critical Period, Psychological; Dopamine; Ethanol; Humans; Illicit Drugs; Models, Animal; Nicotine; Prefrontal Cortex; Recreational Drug Use; Reward | 2020 |
Impact of nicotine, alcohol, and cocaine exposure on germline integrity and epigenome.
Topics: Animals; Cocaine; DNA Methylation; Epigenesis, Genetic; Epigenome; Epigenomics; Ethanol; Gene Expression Regulation, Developmental; Germ Cells; Humans; Nicotine; Substance-Related Disorders; Wills | 2020 |
Social isolation at adolescence: a systematic review on behaviour related to cocaine, amphetamine and nicotine use in rats and mice.
Topics: Amphetamine; Animals; Cocaine; Locomotion; Mice; Nicotine; Rats; Self Administration; Social Isolation; Stress, Psychological; Substance-Related Disorders | 2021 |
[Advances in Immunotherapy for Drug Addiction].
Topics: Cocaine; Humans; Immunotherapy; Methamphetamine; Nicotine; Substance-Related Disorders | 2021 |
The Role of Peroxisome Proliferator-Activated Receptor in Addiction: A Novel Drug Target.
Topics: Alcohols; Analgesics, Opioid; Behavior, Addictive; Cannabis; Cocaine; Humans; Ligands; Methamphetamine; Molecular Targeted Therapy; Neurodegenerative Diseases; Nicotine; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptors; Pharmaceutical Preparations; Protein Isoforms; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2021 |
Selective serotonin reuptake inhibitors in the treatment of depression, anxiety, and post-traumatic stress disorder in substance use disorders: a Bayesian meta-analysis.
Topics: Analgesics, Opioid; Anxiety; Bayes Theorem; Cocaine; Depression; Humans; Nicotine; Selective Serotonin Reuptake Inhibitors; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Tobacco Use Disorder | 2022 |
Substance use during the COVID-19 pandemic: What is really happening?
Topics: Adult; Benzodiazepines; Cocaine; Communicable Disease Control; COVID-19; Cross-Sectional Studies; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Nicotine; Pandemics; Retrospective Studies; SARS-CoV-2; Substance-Related Disorders; Wastewater | 2022 |
Common and distinguishing genetic factors for substance use behavior and disorder: an integrated analysis of genomic and transcriptomic studies from both human and animal studies.
Topics: Aldehyde Dehydrogenase, Mitochondrial; Animals; Cocaine; Epstein-Barr Virus Infections; Genetic Predisposition to Disease; Genome-Wide Association Study; Genomics; Herpesvirus 4, Human; Humans; Nicotine; Polymorphism, Single Nucleotide; Substance-Related Disorders; Tobacco Use Disorder; Transcriptome | 2022 |
Cannabidiol in the context of substance use disorder treatment: A systematic review.
Topics: Animals; Cannabidiol; Cannabis; Cocaine; Humans; Methamphetamine; Nicotine; Substance-Related Disorders | 2022 |
Withdrawal: A key consideration in evaluating whether highly processed foods are addictive.
Topics: Animals; Behavior, Addictive; Carbohydrates; Cocaine; Fast Foods; Feeding Behavior; Humans; Hyperphagia; Nicotine; Retrospective Studies; Substance-Related Disorders | 2022 |
Vaccines as a preventive tool for substance use disorder: A systematic review including a meta-analysis on nicotine vaccines' immunogenicity.
Topics: Cocaine; Humans; Nicotine; Substance-Related Disorders; Vaccination; Vaccines | 2022 |
7 trial(s) available for nicotine and cocaine
| Article | Year |
|---|---|
An acute dose of nicotine enhances cue-induced cocaine craving.
Topics: Adult; Analysis of Variance; Anxiety; Behavior, Addictive; Cocaine-Related Disorders; Conditioning, Psychological; Crack Cocaine; Cross-Over Studies; Cues; Double-Blind Method; Drive; Female; Galvanic Skin Response; Humans; Male; Middle Aged; Nicotine; Nicotinic Agonists; Skin Temperature; Substance Withdrawal Syndrome; Tobacco Use Disorder | 1998 |
Subjective and physiological effects of intravenous nicotine and cocaine in cigarette smoking cocaine abusers.
Topics: Adult; Analysis of Variance; Blood Pressure; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Female; Heart Rate; Humans; Injections, Intravenous; Male; Nicotine; Pain Measurement; Reinforcement, Psychology; Skin Temperature; Smoking; Surveys and Questionnaires | 1999 |
Reversal of diminished inhibitory sensory gating in cocaine addicts by a nicotinic cholinergic mechanism.
Topics: Acetylcholine; Adult; Auditory Perception; Brain; Cocaine; Cocaine-Related Disorders; Cross-Over Studies; Evoked Potentials, Auditory; Female; Hallucinations; Hearing Disorders; Humans; Male; Neural Inhibition; Neuropsychological Tests; Nicotine; Psychotic Disorders; Receptors, Nicotinic | 2001 |
Effects of intravenous cocaine and cigarette smoking on luteinizing hormone, testosterone, and prolactin in men.
Topics: Carbon Monoxide; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Humans; Luteinizing Hormone; Male; Nicotine; Prolactin; Smoking; Substance Withdrawal Syndrome; Testosterone | 2003 |
Correlations of maternal buprenorphine dose, buprenorphine, and metabolite concentrations in meconium with neonatal outcomes.
Topics: Adult; Buprenorphine; Cocaine; Double-Blind Method; Female; Humans; Infant, Newborn; Male; Maternal Behavior; Maternal-Fetal Exchange; Meconium; Methadone; Narcotic Antagonists; Neonatal Abstinence Syndrome; Nicotine; Opiate Alkaloids; Opioid-Related Disorders; Pregnancy; Smoking | 2008 |
Effects of oral caffeine pretreatment on response to intravenous nicotine and cocaine.
Topics: Administration, Oral; Adult; Blood Pressure; Caffeine; Central Nervous System Stimulants; Cocaine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Injections, Intravenous; Male; Middle Aged; Nicotine; Pain Measurement; Surveys and Questionnaires | 2010 |
The sweet spot study-Developing e-liquid product standards for nicotine form and concentration to improve public health: Protocol for a randomized, double-blinded, crossover study.
Topics: Aged; Candy; Cross-Over Studies; Electronic Nicotine Delivery Systems; Humans; Nicotine; Public Health; Randomized Controlled Trials as Topic; United States; Young Adult | 2023 |
429 other study(ies) available for nicotine and cocaine
| Article | Year |
|---|---|
Amnesia-reversal activity of a series of N-[(disubstituted-amino)alkyl] -2-oxo-1-pyrrolidineacetamides, including pramiracetam.
Topics: Amnesia; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Humans; Male; Mice; Mice, Inbred Strains; Pyrrolidines; Structure-Activity Relationship | 1984 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Molecular complexes of cocaine, its active metabolites and some other stimulants with thiamine.
Topics: Caffeine; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Cocaine; Nicotine; Phenylpropanolamine; Thiamine | 1976 |
Maturational changes related to dopamine in the effects of d-amphetamine, cocaine, nicotine, and strychnine on seizure susceptibility.
Topics: Aging; Animals; Cocaine; Dextroamphetamine; Dopamine; Mice; Myoclonus; Nicotine; Seizures; Strychnine | 1979 |
The mechanism of action of nicotine on vascular adrenergic neuroeffector transmission.
Topics: Animals; Aorta; Blood Vessels; Bretylium Compounds; Cocaine; Drug Interactions; Electric Stimulation; Hexamethonium Compounds; In Vitro Techniques; Muscle Contraction; Nicotine; Norepinephrine; Pargyline; Pulmonary Artery; Rabbits; Sympathetic Nervous System; Synaptic Transmission; Time Factors; Tubocurarine; Tyramine | 1977 |
Interactions of delta9-tetrahydrocannabinol with d-amphetamine, cocaine, and nicotine in rats.
Topics: Animals; Body Temperature; Cocaine; Dextroamphetamine; Dronabinol; Drug Interactions; Heart Rate; Male; Motor Activity; Nicotine; Postural Balance; Rats; Time Factors | 1978 |
Amine releasing action of nicotine from rat hypothalamus in vitro.
Topics: Animals; Cocaine; Female; Hypothalamus; In Vitro Techniques; Male; Metaraminol; Nicotine; Rats; Time Factors | 1977 |
Effects of nicotine and cocaine on the release of acetylcholine from isolated human placental villi.
Topics: Acetylcholine; Calcium; Chromatography, Gas; Cocaine; Drug Interactions; Female; Humans; In Vitro Techniques; Nicotine; Placenta; Potassium; Pregnancy; Quaternary Ammonium Compounds | 1977 |
Nicotine-induced relaxation in isolated canine cerebral arteries.
Topics: Animals; Atropine; Bretylium Compounds; Cerebral Arteries; Cocaine; Dogs; Electric Stimulation; Female; Hexamethonium Compounds; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Nicotine; Ouabain; Potassium; Propranolol; Prostaglandins F; Sotalol; Sympathetic Nervous System | 1975 |
Responses of isolated canine cerebral and peripheral arteries to nicotine.
Topics: Animals; Arteries; Bretylium Compounds; Cerebral Arteries; Cocaine; Dogs; Hexamethonium Compounds; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nicotine; Phentolamine; Propranolol; Sotalol | 1975 |
Tissue receptors. Historical scope. Modern view. Perspectives.
Topics: Acetylcholine; Animals; Blood Pressure; Blood Vessels; Carbon Dioxide; Carotid Body; Cats; Chemoreceptor Cells; Cocaine; Electrophysiology; Mechanoreceptors; Nicotine; Oxygen; Pressoreceptors; Procaine; Rabbits; Respiration; Sensory Receptor Cells | 1976 |
Nicotine-like actions of cis-metanicotine and trans-metanicotine.
Topics: Animals; Aorta, Thoracic; Atropine; Cocaine; Drug Interactions; Hexamethonium Compounds; In Vitro Techniques; Intestines; Male; Muscle Contraction; Nicotine; Phentolamine; Pyridines; Rabbits; Stereoisomerism | 1976 |
Effect of cocaine, ethanol or nicotine on ornithine decarboxylase activity in early chick embryo brain.
Topics: Animals; Brain; Chick Embryo; Cocaine; Eflornithine; Ethanol; Nicotine; Organ Size; Ornithine Decarboxylase | 1992 |
First identification of drugs in Egyptian mummies.
Topics: Bone and Bones; Cannabis; Cocaine; Egypt; Female; Hair; Humans; Male; Mummies; Nicotine | 1992 |
Inhibition of dopamine uptake by cocaine and nicotine: tolerance to chronic treatments.
Topics: Animals; Cocaine; Corpus Striatum; Depression, Chemical; Dopamine; Drug Implants; Drug Tolerance; Male; Nicotine; Nucleus Accumbens; Rats; Rats, Inbred Strains | 1992 |
Preexposure to amphetamine and nicotine predisposes rats to self-administer a low dose of cocaine.
Topics: Amphetamine; Animals; Cocaine; Conditioning, Operant; Male; Motor Activity; Nicotine; Rats; Rats, Inbred Strains; Self Administration | 1992 |
Genetic selections for nicotine and cocaine sensitivity in mice.
Topics: Animals; Arousal; Body Temperature Regulation; Cocaine; Dose-Response Relationship, Drug; Mice; Mice, Inbred Strains; Models, Genetic; Motor Activity; Nicotine; Receptors, Neurotransmitter; Selection, Genetic | 1991 |
Pre-exposure to amphetamine but not nicotine sensitizes rats to the motor activating effect of cocaine.
Topics: Amphetamine; Animals; Brain Chemistry; Cocaine; Dopamine Agents; Male; Motor Activity; Nicotine; Rats; Rats, Inbred Strains | 1991 |
Effect of chronic administration of nicotine or cocaine on steroidogenesis in rat adrenocortical cells.
Topics: Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cocaine; In Vitro Techniques; Infusion Pumps, Implantable; Male; Nicotine; Rats; Rats, Inbred Strains; Steroids | 1991 |
Opiate antagonists reduce cocaine but not nicotine self-administration.
Topics: Animals; Cocaine; Conditioning, Operant; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nicotine; Rats; Reinforcement Schedule; Self Administration | 1991 |
Ketotifen and its analogues reduce aversive responding in the rodent.
Topics: Animals; Avoidance Learning; Behavior, Animal; Benzamides; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Diazepam; Ethanol; Exploratory Behavior; Granisetron; Indazoles; Ketotifen; Male; Mice; Mice, Inbred Strains; Nicotine; Radioligand Assay; Rats; Rats, Inbred Strains; Serotonin Antagonists; Social Behavior | 1990 |
Nicotine indirectly inhibits [3H]dopamine uptake at concentrations that do not directly promote [3H]dopamine release in rat striatum.
Topics: Animals; Binding, Competitive; Carbachol; Chlorisondamine; Cocaine; Corpus Striatum; Dimethylphenylpiperazinium Iodide; Dopamine; Dose-Response Relationship, Drug; Male; Mecamylamine; Nicotine; Piperazines; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Synaptosomes | 1991 |
Ondansetron inhibits a behavioural consequence of withdrawing from drugs of abuse.
Topics: Animals; Cocaine; Ethanol; Exploratory Behavior; Illicit Drugs; Imidazoles; Male; Mice; Nicotine; Ondansetron; Rats; Rats, Inbred Strains; Serotonin Antagonists; Social Behavior; Substance Withdrawal Syndrome | 1990 |
The price of addiction.
Topics: Alcoholism; Cocaine; Delivery of Health Care; Humans; Nicotine; Substance-Related Disorders | 1990 |
Bromocriptine self-administration and bromocriptine-reinstatement of cocaine-trained and heroin-trained lever pressing in rats.
Topics: Animals; Bromocriptine; Clonidine; Cocaine; Conditioning, Operant; Ethanol; Heroin; Male; Nicotine; Rats; Reinforcement Schedule; Reinforcement, Psychology; Self Administration | 1990 |
The effect of ketotifen in rodent models of anxiety and on the behavioural consequences of withdrawing from treatment with drugs of abuse.
Topics: Animals; Anxiety; Behavior, Animal; Cocaine; Conditioning, Operant; Diazepam; Ethanol; Ketotifen; Male; Mice; Nicotine; Rats; Rats, Inbred Strains; Species Specificity; Substance Withdrawal Syndrome; Substance-Related Disorders | 1990 |
Behavioral and EEG studies of acute cocaine administration: comparisons with morphine, amphetamine, pentobarbital, nicotine, ethanol and marijuana.
Topics: Adult; Affect; Alpha Rhythm; Amphetamine; Arousal; Cerebral Cortex; Cocaine; Dose-Response Relationship, Drug; Dronabinol; Electroencephalography; Ethanol; Euphoria; Female; Humans; Male; Morphine; Nicotine; Pentobarbital; Signal Processing, Computer-Assisted | 1989 |
Street drugs.
Topics: Cocaine; Humans; Illicit Drugs; Methamphetamine; Nicotine | 1989 |
The actions of nicotine and cocaine in a mouse model of anxiety.
Topics: Animals; Anxiety; Behavior, Animal; Cocaine; Discrimination, Psychological; Disease Models, Animal; Light; Male; Mice; Mice, Inbred Strains; Nicotine; Substance Withdrawal Syndrome | 1989 |
Aversive environmental stimuli as a factor in the psychostimulant response to nicotine.
Topics: Animals; Behavior, Animal; Cocaine; Dextroamphetamine; Dose-Response Relationship, Drug; Environment; Male; Motor Activity; Nicotine; Rats; Rats, Inbred Strains | 1989 |
Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Antipsychotic Agents; Caudate Nucleus; Cocaine; Dopamine; Ethanol; Homovanillic Acid; Illicit Drugs; Kinetics; Male; Narcotics; Nicotine; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Septal Nuclei; Synapses | 1988 |
Maternal-fetal transfer of abused substances: pharmacokinetic and pharmacodynamic data.
Topics: Amphetamine; Animals; Cocaine; Dronabinol; Female; Fetus; Humans; Kinetics; Lysergic Acid Diethylamide; Maternal-Fetal Exchange; Meperidine; Methadone; Morphine; Nicotine; Phencyclidine; Pregnancy; Substance-Related Disorders | 1985 |
Ascorbic acid and striatal transport of [3H] 1-methyl-4-phenylpyridine (MPP+) and [3H] dopamine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Ascorbic Acid; Biological Transport; Cocaine; Corpus Striatum; Dopamine; Kinetics; Mazindol; Mice; Nicotine; Piperazines; Pyridines; Synaptosomes | 1988 |
Mapping the cerebral distributions of action of euphoriant drugs.
Topics: Animals; Autoradiography; Brain; Cocaine; Glucose; Male; Morphine; Nicotine; Phencyclidine; Rats; Rats, Inbred F344; Tissue Distribution | 1986 |
Some effects of d-amphetamine, caffeine, nicotine and cocaine on schedule-controlled responding of the mouse.
Topics: Animals; Caffeine; Cocaine; Conditioning, Operant; Dextroamphetamine; Male; Mice; Nicotine; Reaction Time; Reinforcement Schedule | 1986 |
The effects of food deprivation on the self-administration of psychoactive drugs.
Topics: Animals; Cocaine; Dextroamphetamine; Diazepam; Food Deprivation; Macaca mulatta; Male; Nicotine; Perphenazine; Reinforcement, Psychology; Self Administration; Substance-Related Disorders | 1987 |
Discriminative stimulus properties of cocaine in pigeons.
Topics: Alkaloids; Animals; Apomorphine; Cocaine; Columbidae; Dextroamphetamine; Discrimination, Psychological; Dopamine; Lidocaine; Nicotine; Oxazepam; Pentobarbital; Procaine; Psychotropic Drugs; Reinforcement Schedule | 1985 |
Intravenous self-administration of nicotine: with and without schedule-induction.
Topics: Animals; Cocaine; Conditioning, Operant; Food; Injections, Intravenous; Macaca mulatta; Male; Nicotine; Reinforcement Schedule; Self Administration | 1985 |
Effects of nicotine, cocaine and some of their metabolites on schedule-controlled responding by beagle dogs and squirrel monkeys.
Topics: Animals; Cocaine; Conditioning, Psychological; Cotinine; Dogs; Dose-Response Relationship, Drug; Female; Food; Male; Nicotine; Pyrrolidinones; Saimiri | 1985 |
The origin of the hypertensive effect of arecoline in rats.
Topics: Adrenal Glands; Adrenalectomy; Animals; Arecoline; Arteries; Atropine; Blood Pressure; Chemoreceptor Cells; Cocaine; Drug Synergism; Female; Ganglionic Blockers; Hexamethonium Compounds; Hypertension; Hypotension; Injections, Intra-Arterial; Injections, Intravenous; Male; Nicotine; Parasympatholytics; Rats; Reserpine; Vagotomy; Vagus Nerve | 1973 |
Rhinitis medicamentosa.
Topics: Aspirin; Cocaine; Drug Hypersensitivity; Ephedrine; Epinephrine; Estrogens; Humans; Iodides; Ipecac; Nasal Decongestants; Nasal Mucosa; Nicotine; Plants, Medicinal; Quinine; Rauwolfia; Rhinitis; Smoking; Substance-Related Disorders; Tyrothricin | 1968 |
Effect of nicotine and other drugs on the release of 3H-norepinephrine and 3H-dopamine from rat brain slices.
Topics: Acetylcholine; Animals; Brain; Carbachol; Cerebellum; Cerebral Cortex; Cocaine; Corpus Striatum; Culture Media; Deamination; Dopamine; Edetic Acid; Hexamethonium Compounds; Hypothalamus; In Vitro Techniques; Lidocaine; Methacholine Compounds; Methylation; Morphine; Nicotine; Norepinephrine; Peripheral Nerves; Phenoxybenzamine; Rats; Tritium | 1974 |
Effects of some nicotine metabolites and related compounds on isolated smooth muscle.
Topics: Acetates; Alkaloids; Animals; Atropine; Bretylium Compounds; Cocaine; Hexamethonium Compounds; Intestine, Small; Muscle, Smooth; Niacinamide; Nicotine; Physostigmine; Pyridines; Pyrrolidines; Rabbits; Rats; Tetraethylammonium Compounds | 1968 |
Observations on the ganglion-stimulating action of angiotensin and bradykinin.
Topics: Angiotensin II; Animals; Bradykinin; Cats; Cocaine; Ganglia, Autonomic; Hexamethonium Compounds; Morphine; Nicotine; Nictitating Membrane | 1966 |
Mechanism of the musculotropic activity of angiotensin on the isolated guinea-pig seminal vsecile.
Topics: Acetylcholine; Angiotensin II; Animals; Atropine; Catecholamines; Cocaine; Epinephrine; Guanethidine; Guinea Pigs; Male; Mecamylamine; Muscle Contraction; Muscle, Smooth; Nicotine; Phentolamine; Piperazines; Seminal Vesicles; Tachyphylaxis; Tetracaine; Tyramine | 1968 |
Neurotransmission in central nervous tissue: a study of isolated rabbit retina.
Topics: Action Potentials; Aminobutyrates; Animals; Atropine; Catecholamines; Cocaine; Glutamates; Glycine; In Vitro Techniques; Isoproterenol; Light; Lysergic Acid Diethylamide; Methoxamine; Methysergide; Nicotine; Parasympathomimetics; Phentolamine; Picrotoxin; Piperazines; Rabbits; Retina; Strychnine; Sympatholytics; Sympathomimetics; Synapses; Synaptic Transmission; Tubocurarine | 1969 |
The pharmacological basis of drug dependence.
Topics: Amphetamine; Barbiturates; Cannabis; Central Nervous System; Cocaine; Ethanol; Hallucinogens; Heroin; Humans; Morphine; Nicotine; Pharmacology; Substance Withdrawal Syndrome; Substance-Related Disorders; Synaptic Transmission | 1970 |
Some structural considerations of the reactivity of vascular smooth muscle.
Topics: Angiotensin II; Animals; Aorta; Blood Vessels; Bretylium Compounds; Catecholamines; Cocaine; Diffusion; Electric Stimulation; Imipramine; Methods; Muscle Contraction; Muscle, Smooth; Neural Conduction; Neuroeffector Junction; Nicotine; Norepinephrine; Pulmonary Artery; Rabbits; Serotonin; Tritium; Tyramine | 1969 |
(3H)-adenosine nucleotide and (3H)-noradrenaline uptake by cold stored guinea-pig taenia caecum; mechanical effects and release of (3H)-adenosine nucleotide by noradrenaline, papaverine, and nitroglycerine.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cecum; Cocaine; Cyclic AMP; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Nicotine; Nitroglycerin; Norepinephrine; Oligomycins; Papaverine; Phenoxybenzamine; Phentolamine; Propranolol; Refrigeration; Tritium | 1973 |
Proceedings: Effect of nicotine and nicotine monomethiodide on vascular adrenergic neuroeffector transmission.
Topics: Animals; Aorta; Bretylium Compounds; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Hexamethonium Compounds; In Vitro Techniques; Iodine; Nerve Endings; Nicotine; Norepinephrine; Pulmonary Artery; Rabbits; Sympathetic Nervous System; Synaptic Transmission; Tritium; Tubocurarine; Tyramine | 1974 |
A direct and an indirect action of 5-hydroxytryptamine on the distal part of the isolated colon of the rat.
Topics: Acetylcholine; Animals; Cholinesterase Inhibitors; Cocaine; Colon; Hexamethonium Compounds; Histamine; Lysergic Acid Diethylamide; Male; Mecamylamine; Muscle Contraction; Muscle, Smooth; Nicotine; Piperazines; Procaine; Rats; Scopolamine; Serotonin | 1965 |
A pharmacological investigation of human isolated stomach.
Topics: Acetylcholine; Cocaine; Epinephrine; Ergoloid Mesylates; Ethanolamines; Guanethidine; Hexamethonium Compounds; Histamine; Histamine H1 Antagonists; Humans; In Vitro Techniques; Isoproterenol; Lidocaine; Methysergide; Neostigmine; Nicotine; Norepinephrine; Pentolinium Tartrate; Physostigmine; Piperazines; Potassium Chloride; Scopolamine; Serotonin; Stomach; Sympathomimetics | 1966 |
The site of action of drugs on the isolated taenia caeci from the guinea-pig.
Topics: Acetylcholine; Animals; Cecum; Cocaine; Female; Guinea Pigs; Hexamethonium Compounds; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Insecticides; Lysergic Acid Diethylamide; Male; Mecamylamine; Morphine; Muscle Contraction; Nicotine; Piperazines; Procaine; Scopolamine; Serotonin; Sympathomimetics | 1966 |
An analysis of the action of drugs on the circular muscle strips from the caecum of the guinea-pig.
Topics: Acetylcholine; Animals; Cecum; Cocaine; Cold Temperature; Drug Synergism; Ganglia; Guinea Pigs; Histamine; In Vitro Techniques; Insecticides; Muscle Contraction; Muscle, Smooth; Neostigmine; Nerve Tissue; Nicotine; Pentolinium Tartrate; Piperazines; Procaine; Scopolamine; Serotonin; Sympathomimetics | 1966 |
Inhibition of the taenia of the guinea-pig caecum by acetylcholine, nicotine or 5-hydroxytryptamine.
Topics: Acetylcholine; Animals; Cecum; Cocaine; Ergoloid Mesylates; Guanethidine; Guinea Pigs; Hexamethonium Compounds; Histamine; Isoproterenol; Nicotine; Norepinephrine; Pentolinium Tartrate; Phenoxybenzamine; Piperazines; Procaine; Reserpine; Scopolamine; Serotonin; Sympatholytics | 1966 |
Mechanisms of sympathomimetic effects of dichloroisoproterenol: comparison with tyramine, nicotine and norepinephrine.
Topics: Animals; Atropine; Cocaine; Diaphragm; Drug Antagonism; Ganglionic Blockers; Guanidines; Heart; Heart Atria; Hexamethonium Compounds; Imipramine; In Vitro Techniques; Iproniazid; Isoproterenol; Morphine; Nicotine; Norepinephrine; Pentolinium Tartrate; Phenoxybenzamine; Propranolol; Rats; Sympatholytics; Tranylcypromine; Tyramine | 1967 |
Effects of various drugs on the bronchoconstriction produced by transmural stimulation of the perfused guinea pig lung.
Topics: Acetylcholine; Aminobenzoates; Animals; Atropine; Biphenyl Compounds; Bronchi; Cocaine; Cyproheptadine; Dibucaine; Drug Antagonism; Drug Synergism; Electric Stimulation; Ganglionic Blockers; Guinea Pigs; Hexamethonium Compounds; Histamine; Isoproterenol; Lung; Nicotine; Perfusion; Physostigmine; Pilocarpine; Serotonin; Tetracaine; Tremorine | 1967 |
An analysis of the sympathomimetic effects of acetylcholine of the rat ileum.
Topics: Acetylcholine; Amphetamine; Animals; Bretylium Compounds; Choline; Cocaine; Dextroamphetamine; Drug Synergism; Epinephrine; Ethanolamines; Female; Guanethidine; Hexamethonium Compounds; Ileum; In Vitro Techniques; Male; Mecamylamine; Muscle Contraction; Muscle, Smooth; Nicotine; Pempidine; Phentolamine; Rats; Reserpine; Scopolamine; Xylenes | 1967 |
[Mechanism of contraction caused by nicotine on the isolated rabbit aorta, with reference to catecholamine release].
Topics: Animals; Aorta; Autonomic Agents; Bis-Trimethylammonium Compounds; Bretylium Compounds; Catecholamines; Cocaine; Edetic Acid; Ergotamine; Guanethidine; Hexamethonium Compounds; Hydrazines; In Vitro Techniques; Mecamylamine; Muscle Contraction; Nicotine; Norepinephrine; Pyrogallol; Rabbits; Reserpine; Tyramine; Yohimbine | 1967 |
[Mechanism of the contraction by bretylium in the isolated aortic strip of rabbits, with special reference to catecholamine liberation].
Topics: Animals; Aorta; Bis-Trimethylammonium Compounds; Bretylium Compounds; Catecholamines; Cocaine; Dibenzylchlorethamine; Ergotamine; Ganglionic Blockers; In Vitro Techniques; Muscle Contraction; Nicotine; Norepinephrine; Pyrogallol; Rabbits; Reserpine; Tachyphylaxis; Tyramine | 1967 |
The isolated expansor secundariorum--a smooth muscle preparation from the wing of the domestic fowl.
Topics: Acetylcholine; Animals; Chickens; Cocaine; Drug Synergism; Epinephrine; Histamine; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Phentolamine; Propranolol; Reserpine; Serotonin; Temperature; Tyramine; Wings, Animal | 1968 |
Uptake of (3H)noradrenaline in the rat heart during increased sympathetic nervous activity associated with cold.
Topics: Angiotensin II; Animals; Cocaine; Cold Temperature; Desipramine; Male; Myocardium; Nicotine; Norepinephrine; Rats; Tritium; Tyramine | 1968 |
[Spasmolytic effect of aryl-substituted alpha-pyrones and aqueous extracts of Piper methysticum Forst].
Topics: Animals; Anticonvulsants; Benzocaine; Chromatography, Thin Layer; Cocaine; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Muscle Contraction; Muscle, Smooth; Nicotine; Papaverine; Parasympathomimetics; Plant Extracts; Procaine; Pyrans; Serotonin | 1969 |
[The effect of cholinomimetics, biogenic amines and their antagonists on the local anesthetic effect].
Topics: Anesthesia, Local; Animals; Cocaine; Cornea; Diphenhydramine; Diphenylacetic Acids; Epinephrine; Guinea Pigs; Histamine; Nicotine; Pilocarpine; Promethazine; Sensory Receptor Cells; Serotonin; Sympatholytics; Sympathomimetics; Tetracaine | 1967 |
[Potentiating effects of choline on the action of phenyl acetate. 5. Effects of inhibitors of acetylcholine liberation].
Topics: Acetylcholine; Animals; Choline; Cocaine; Cold Temperature; Drug Synergism; Electric Stimulation; Epinephrine; Ganglionic Blockers; Guinea Pigs; Hemicholinium 3; Histamine; Ileum; In Vitro Techniques; Morphine; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Oxygen; Phenylacetates; Picrates; Piperazines; Procaine; Strychnine; Tetrodotoxin | 1971 |
Neural mechanism of the relaxing responses of guinea-pig taenia coli.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Amino Acids; Aminobutyrates; Animals; Atropine; Bretylium Compounds; Cocaine; Colon; Dopamine; Electric Stimulation; Epinephrine; Guanethidine; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Phenoxybenzamine; Phentolamine; Propranolol; Serotonin; Tetrodotoxin | 1971 |
The action of choline on the superior cervical ganglion of the cat.
Topics: Animals; Atropine; Autonomic Fibers, Postganglionic; Autonomic Fibers, Preganglionic; Cats; Choline; Cocaine; Denervation; Dimethylphenylpiperazinium Iodide; Drug Synergism; Electric Stimulation; Female; Ganglia, Autonomic; Ganglionic Blockers; Ganglionic Stimulants; Hexamethonium Compounds; Male; Methadone; Morphine; Nicotine; Nictitating Membrane; Sensory Receptor Cells | 1972 |
Optimization of extraction and separation of narcotics from urine.
Topics: Chromatography, Gas; Chromatography, Thin Layer; Cocaine; Codeine; Diphenhydramine; Evaluation Studies as Topic; Glucosidases; Humans; Indicators and Reagents; Meperidine; Methadone; Methaqualone; Methods; Morphine; Nalorphine; Narcotics; Nicotine; Pentazocine; Phenmetrazine; Time Factors | 1974 |
[Effect of 1-ethyl-4-(2-morpholinoethyl)-3, 3-diphenyl-2-pyrrolidinone hydrochloride hydrate (doxapram) on respiration and circulation].
Topics: Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Cocaine; Cordotomy; Dogs; Doxapram; Drug Synergism; Female; Femoral Artery; Guanethidine; Heart Rate; Hemodynamics; Morpholines; Nicotine; Norepinephrine; Oxygen; Phenoxybenzamine; Regional Blood Flow; Reserpine; Respiration; Tyramine | 1974 |
[The mechanism of relaxation produced by periarterial nerve stimulation, nicotine and tyramine in the isolated rabbit ileum, particularly in relation to acetylcholine and calcium].
Topics: Acetylcholine; Animals; Bretylium Compounds; Calcium; Cocaine; Depression, Chemical; Dibenzylchlorethamine; Electric Stimulation; Epinephrine; Female; Guanethidine; Hemicholinium 3; Hexamethonium Compounds; Ileum; In Vitro Techniques; Intestine, Small; Male; Methyldopa; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Propranolol; Rabbits; Tachyphylaxis; Tyramine | 1972 |
[Pharmacological actions of N-ethylmaleimide (NEM). 1. Effects of NEM on sympathetic synapses in guinea pigs].
Topics: Acetylcholine; Animals; Anura; Calcium; Cocaine; Cysteine; Electric Stimulation; Ethylmaleimide; Guanethidine; Guinea Pigs; Heart Atria; Heart Rate; Hypogastric Plexus; In Vitro Techniques; Male; Muscle Contraction; Nicotine; Potassium; Propranolol; Reserpine; Spinal Cord; Sympathetic Nervous System; Synapses; Vas Deferens | 1972 |
Effect of 4,4'-biphenylenebis-((2-oxoethylene)-bis-(2,2-diethoxyethyl))dimethylammonium dibromide (DMAE) on accumulation and nicotine-induced release of norepinephrine in the heart.
Topics: Animals; Biphenyl Compounds; Bromine; Cocaine; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Male; Myocardium; Neurons; Nicotine; Norepinephrine; Quaternary Ammonium Compounds; Rats; Time Factors; Tritium | 1973 |
Myogenic peristalsis in isolated preparations of chicken oesophagus.
Topics: Acetylcholine; Animals; Chickens; Cocaine; Esophagus; Female; Gastrointestinal Motility; In Vitro Techniques; Male; Methysergide; Morphine; Mucous Membrane; Muscle Contraction; Nicotine; Norepinephrine; Papaverine; Phentolamine; Picrotoxin; Pressure; Propranolol; Rectum; Scopolamine; Stimulation, Chemical; Strychnine; Tetrodotoxin; Tubocurarine; Vagus Nerve | 1973 |
The action of hordenine on the superior cervical ganglion of the cat.
Topics: Adrenal Glands; Adrenalectomy; Animals; Atropine; Cats; Cocaine; Dimethylamines; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Epinephrine; Female; Ganglia, Spinal; Hexamethonium Compounds; In Vitro Techniques; Male; Methadone; Morphine; Muscle Contraction; Nicotine; Nictitating Membrane; Phenethylamines; Propranolol; Receptors, Adrenergic; Receptors, Cholinergic; Time Factors | 1973 |
Pharmacological nature of adrenergic innervation in rat aorta.
Topics: Animals; Aorta; Aorta, Thoracic; Autoradiography; Cocaine; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Fluorescence; Histocytochemistry; Hydroxydopamines; In Vitro Techniques; Muscle Contraction; Nicotine; Norepinephrine; Rats; Sympathetic Nervous System; Time Factors; Tritium; Tyramine | 1973 |
Specificity of blockade of the nicotine-induced release of 3H-norepinephrine from adrenergic neurons of the guinea-pig heart by various pharmacological agents.
Topics: Aminophylline; Animals; Bretylium Compounds; Cocaine; Colchicine; Guinea Pigs; Heart; Hexamethonium Compounds; In Vitro Techniques; Lidocaine; Morphine; Myocardium; Neurons; Nicotine; Norepinephrine; Perfusion; Potassium Chloride; Prostaglandins; Stimulation, Chemical; Tritium; Tyramine | 1974 |
History and pharmacology of psychedelic drugs.
Topics: Amphetamine; Caffeine; Cannabis; Coca; Cocaine; Condiments; Ethanol; Ethyl Ethers; Hallucinogens; History, 20th Century; History, Ancient; Humans; Lysergic Acid Diethylamide; Mescaline; Nicotine; Nitrous Oxide; Plants, Medicinal; Substance-Related Disorders | 1971 |
Peristaltic activity of isolated stomach and its modification by drugs.
Topics: Acetylcholine; Animals; Anura; Cocaine; Gastrointestinal Motility; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Morphine; Nicotine; Physostigmine; Rabbits; Stomach; Tubocurarine | 1972 |
Uptake of nicotine by the sympathetic nerve terminals in the blood vessel.
Topics: Animals; Aorta; Autonomic Fibers, Postganglionic; Blood Vessels; Cocaine; Desipramine; Extracellular Space; Guanethidine; In Vitro Techniques; Muscle Contraction; Nerve Endings; Nicotine; Norepinephrine; Pulmonary Artery; Rabbits; Sympathetic Nervous System; Time Factors; Tritium | 1972 |
Differential antagonism between DMAE (a hemicholinium derivative) and atropine on contractile responses of the rat ileum.
Topics: Acetylcholine; Animals; Atropine; Biphenyl Compounds; Cocaine; Depression, Chemical; Drug Antagonism; Hexamethonium Compounds; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Nicotine; Quaternary Ammonium Compounds; Rats; Strychnine | 1971 |
Relationship between chronic vagal denervation and the response of the isolated rat ileum to nicotine.
Topics: Acetylcholine; Animals; Atropine; Biphenyl Compounds; Cocaine; Drug Antagonism; Hexamethonium Compounds; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle Denervation; Muscle, Smooth; Myenteric Plexus; Nicotine; Quaternary Ammonium Compounds; Rats; Strychnine; Vagotomy | 1971 |
The action of arecoline on the superior cervical ganglion of the cat.
Topics: Animals; Atropine; Cats; Cocaine; Dimethylphenylpiperazinium Iodide; Drug Antagonism; Female; Ganglia, Autonomic; Ganglionic Stimulants; Male; Methadone; Morphine; Nicotine; Nicotinic Acids; Nictitating Membrane; Parasympathomimetics; Piperazines; Receptors, Drug; Stimulation, Chemical; Sympathetic Nervous System | 1971 |
[Pharmacological responses of the pyloric antrum strip of the rat stomach, with special reference to the mechanism of the contractions caused by serotonin and nicotine, relaxation of transmural stimulation and contraction and relaxation by tyramine].
Topics: Acetylcholine; Animals; Atropine; Barium; Bretylium Compounds; Cocaine; Depression, Chemical; Dibenzylchlorethamine; Haloperidol; In Vitro Techniques; Methysergide; Morphine; Muscle Contraction; Nicotine; Phenoxybenzamine; Physostigmine; Procaine; Propranolol; Pylorus; Rats; Receptors, Drug; Scopolamine; Serotonin; Stimulation, Chemical; Tyramine | 1971 |
A comparison of the effects of tyramine and ephedrine on atrial contractions in rabbits and guinea-pigs.
Topics: Animals; Cocaine; Ephedrine; Epinephrine; Guinea Pigs; Heart Atria; In Vitro Techniques; Muscle Contraction; Nicotine; Potassium Chloride; Rabbits; Reserpine; Sodium Chloride; Stimulation, Chemical; Tyramine | 1967 |
Comparative studies of the adrenergic relaxations in the excised jejunum of rat, evoked by nicotine, tyramine, histamine, calcium and transmural stimulation; with a special reference to the catecholamine release.
Topics: Animals; Bretylium Compounds; Calcium; Catecholamines; Cocaine; Dibenzylchlorethamine; Histamine; Jejunum; Nicotine; Norepinephrine; Propranolol; Rats; Relaxation; Reserpine; Stimulation, Chemical; Sympathetic Nervous System; Tachyphylaxis; Tyramine | 1969 |
Evidence for biogenic amine receptors in toad sciatic nerves.
Topics: Animals; Anura; Axons; Chlorpromazine; Chlorzoxazone; Cocaine; Drug Antagonism; Epinephrine; Histamine; Imipramine; Lysergic Acid Diethylamide; Membranes; Neural Conduction; Nicotine; Nicotinic Acids; Pentolinium Tartrate; Potassium Chloride; Procaine; Sciatic Nerve; Sensory Receptor Cells; Serotonin; Sodium; Time Factors | 1969 |
Thiamine alkyl disulfides against actions of potassium and quinidine on guinea-pig atria.
Topics: Animals; Catecholamines; Cell Membrane; Cocaine; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Muscle Contraction; Nicotine; Potassium; Quinidine; Reserpine; Strophanthins; Sulfides; Thiamine | 1969 |
A new muscarinic agent: 1,4,5,6-tetrahydro-5-phenoxypyrimidine (AH 6405).
Topics: Animals; Anura; Atropine; Cats; Cocaine; Ganglia, Autonomic; Guinea Pigs; Heart; In Vitro Techniques; Injections, Intra-Arterial; Injections, Intravenous; Muscle, Smooth; Nicotine; Parasympathomimetics; Pentolinium Tartrate; Rabbits; Stimulation, Chemical | 1970 |
The sympathomimetic effect of gallamine on the heart.
Topics: Acetylcholine; Animals; Atropine; Bretylium Compounds; Cats; Cocaine; Female; Gallamine Triethiodide; Guinea Pigs; Heart; Heart Rate; Hexamethonium Compounds; Histamine; In Vitro Techniques; Male; Muscle Contraction; Nerve Endings; Nicotine; Norepinephrine; Propranolol; Reserpine; Sympathetic Nervous System; Tachyphylaxis; Tritium; Tubocurarine; Tyramine | 1970 |
Water structure in anesthetic action: time-dependence D2O effects on nerve.
Topics: Action Potentials; Anesthesia; Anesthetics; Anesthetics, Local; Animals; Anura; Calcium; Cocaine; Depression, Chemical; Deuterium; Ethanol; Ethyl Ethers; Glucose; In Vitro Techniques; Lidocaine; Models, Biological; Neural Conduction; Nicotine; Ouabain; Oxides; Phosphates; Procaine; Sciatic Nerve; Stimulation, Chemical; Temperature; Time Factors; Water | 1970 |
Blockade of the nicotine-induced norepinephrine release by cocaine, phenoxybenzamine and desipramine.
Topics: Action Potentials; Animals; Axons; Bretylium Compounds; Cocaine; Desipramine; Electric Stimulation; Guanethidine; Muscle Contraction; Nicotine; Norepinephrine; Phenoxybenzamine; Pulmonary Artery; Rabbits; Reserpine; Tetrodotoxin; Tritium | 1970 |
Effects of nicotine and tyramine on contractile activity of the colon.
Topics: Adrenal Glands; Adrenalectomy; Animals; Catecholamines; Cocaine; Colon; Dogs; Female; Gastrointestinal Motility; Hexamethonium Compounds; Male; Muscle Contraction; Nerve Endings; Nicotine; Propranolol; Reserpine; Tolazoline; Tyramine | 1970 |
Adrenergic innervation and cocaine-induced potentiation of adrenergic responses of aortic strips from young and old rabbits.
Topics: Aging; Animals; Aorta, Thoracic; Calcium; Cobalt; Cocaine; Cold Temperature; Drug Synergism; Histocytochemistry; Male; Manganese; Microscopy, Fluorescence; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Phenylephrine; Pyrogallol; Rabbits; Receptors, Adrenergic; Reserpine; Tyramine | 1971 |
The uptake and release of noradrenaline in the blood vessels of the isolated rabbit's ear under aerobic and anaerobic conditions.
Topics: Animals; Blood Vessels; Bretylium Compounds; Cocaine; Drug Synergism; Ear; Electric Stimulation; Immune Sera; In Vitro Techniques; Nicotine; Norepinephrine; Rabbits; Sympathetic Nervous System; Synapses; Tyramine; Vascular Resistance | 1967 |
Sites of action of some partial agonists on the isolated guinea-pig ileum.
Topics: Acetylcholine; Animals; Atropine; Choline; Cocaine; Depression, Chemical; Dibenzylchlorethamine; Ethanol; Guinea Pigs; Hexamethonium Compounds; Ileum; Male; Morphine; Muscle Contraction; Nicotine; Pilocarpine; Stimulation, Chemical; Strychnine | 1968 |
Separation and identification of alkaloids by paper electrophoresis and its application in medico-legal cases.
Topics: Aconitum; Alkaloids; Atropa belladonna; Cocaine; Codeine; Color; Electrophoresis; Ephedrine; Fluorescence; Forensic Medicine; Methods; Morphine; Nicotine; Noscapine; Papaverine; Parasympathomimetics; Physostigmine; Plants, Medicinal; Plants, Toxic; Procaine; Quinine; Solanine; Strychnine; Thebaine; Ultraviolet Rays | 1968 |
Analysis of the inhibitory innervation of the isolated gerbil colon.
Topics: Animals; Bretylium Compounds; Cocaine; Colon; Drug Antagonism; Epinephrine; Female; Gerbillinae; Guanethidine; Hexamethonium Compounds; Isoproterenol; Male; Nicotine; Norepinephrine; Phenoxybenzamine; Phentolamine; Phenylephrine; Procaine; Propranolol; Reserpine; Sympathomimetics; Tyramine | 1968 |
Antagonism of ganglionic stimulants by alpha, alpha'-bis-(dimethylammoniumacetaldehyde diethylacetal)-p,p'-diacetylbiphenyl bromide (DMAE).
Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Cats; Cocaine; Dogs; Electric Stimulation; Hexamethonium Compounds; Nicotine; Nictitating Membrane; Piperazines; Potassium Chloride; Quaternary Ammonium Compounds; Respiration; Splanchnic Nerves; Sympathomimetics; Vagus Nerve | 1968 |
The stimulation of canine prostatic secretion by substances with ganglion-stimulating actions.
Topics: Animals; Atropine; Carbamates; Castration; Cocaine; Dogs; Hexamethonium Compounds; Male; Nicotine; Pilocarpine; Prostate; Pyrrolidines; Quaternary Ammonium Compounds; Testis; Testosterone | 1969 |
Action of prostaglandin E 1 on the longitudinal muscle of the guinea-pig isolated colon.
Topics: Acetylcholine; Animals; Cocaine; Colon; Guinea Pigs; In Vitro Techniques; Lidocaine; Muscle, Smooth; Nicotine; Prostaglandins; Scopolamine; Tetrodotoxin | 1969 |
Effect of atropine and DMAE (a hemicholinium derivative) on contractile responses of the guinea pig ileum.
Topics: Acetylcholine; Animals; Atropine; Cocaine; Electric Stimulation; Female; Guinea Pigs; Hexamethonium Compounds; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Nicotine; Parasympatholytics; Quaternary Ammonium Compounds | 1969 |
Inhibition of the release of acetylcholine from isolated guinea-pig ileum by crystalline tetrodotoxin.
Topics: Acetylcholine; Animals; Cocaine; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Muscle, Smooth; Nicotine; Serotonin; Tetrodotoxin; Toxins, Biological | 1966 |
Hypoglycemic activity and pharmacological picture of 4-(1-naphthyl)butylamine derivatives.
Topics: Acetylcholine; Animals; Atropine; Behavior, Animal; Blood Glucose; Blood Pressure; Butylamines; Chemistry, Organic; Chlorpromazine; Chlorpropamide; Cocaine; Cough; Diphenhydramine; Diuresis; Edema; Guinea Pigs; Hexamethonium Compounds; Histamine; Hydrochlorothiazide; Morphine; Naphthalenes; Nicotine; Organic Chemistry Phenomena; Phenylbutazone; Rats; Serotonin; Spasm | 1966 |
Mode of action of vasopressin on isolated proximal colon of the guinea-pig.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Cocaine; Cold Temperature; Colon; Guinea Pigs; Hexamethonium Compounds; Histamine; Hypoxia; In Vitro Techniques; Mecamylamine; Morphine; Muscle Contraction; Nicotine; Pentolinium Tartrate; Procaine; Scopolamine; Serotonin; Tetraethylammonium Compounds; Vasopressins | 1966 |
Blockade of adrenergic and cholinergic transmissions by emetine.
Topics: Acetylcholine; Amphetamine; Animals; Anura; Atropine; Cats; Cocaine; Colon; Diaphragm; Dopamine; Drug Antagonism; Drug Synergism; Electric Stimulation; Electrophysiology; Emetine; Ganglia; Gastrointestinal Motility; Guinea Pigs; Hexamethonium Compounds; Ileum; In Vitro Techniques; Neuromuscular Junction; Neurons; Nicotine; Nictitating Membrane; Norepinephrine; Phrenic Nerve; Physostigmine; Rabbits; Rats; Scopolamine; Sympathetic Nervous System | 1966 |
Influence of cocaine on the uptake of H3-norepinephrine and on the responses of isolated guinea-pig atria to sympathomimetic amines.
Topics: Animals; Cocaine; Drug Synergism; Epinephrine; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Isoproterenol; Myocardium; Nicotine; Norepinephrine; Piperazines; Reserpine; Sympathomimetics; Tritium; Tyramine | 1967 |
Release of intestinal 5-hydroxytryptamine by morphine and related agents.
Topics: Acetylcholine; Animals; Apomorphine; Calcium; Cocaine; Dogs; Female; Guinea Pigs; Ileum; Injections, Intravenous; Intestinal Mucosa; Intestines; Levorphanol; Male; Meperidine; Methadone; Morphine; Nalorphine; Nicotine; Rats; Reserpine; Serotonin; Tachyphylaxis; Uterus | 1967 |
Sympathetic nerve-free vascular muscle.
Topics: Animals; Aorta; Cocaine; Denervation; Electric Stimulation; In Vitro Techniques; Muscle Contraction; Nicotine; Norepinephrine; Rabbits; Tyramine | 1967 |
Mechanism of secretion from the adrenal medulla. II. Release of catecholamines and storage vesicle protein in response to chemical stimulation.
Topics: Acetylcholine; Adrenal Medulla; Animals; Barium; Calcium; Catecholamines; Cats; Cattle; Cocaine; Immunoelectrophoresis; In Vitro Techniques; Mixed Function Oxygenases; Nicotine; Perfusion; Phosphates; Proteins; Temperature; Transferases | 1967 |
Saturable (3H)cocaine binding in central nervous system of mouse.
Topics: Animals; Brain; Cell Membrane; Cocaine; Male; Mice; Morphine; Naloxone; Neurotransmitter Agents; Nicotine; Tubocurarine | 1980 |
Progress report from the NIDA Addiction Research Center (preclinical laboratory), Lexington, Kentucky.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Cocaine; Dogs; Guinea Pigs; Humans; Kinetics; Male; Nicotine; Opioid-Related Disorders; Oxymorphone; Phenazocine; Phencyclidine; Rats; Self Administration; Stereoisomerism | 1983 |
Formaldehyde production promoted by rat nasal cytochrome P-450-dependent monooxygenases with nasal decongestants, essences, solvents, air pollutants, nicotine, and cocaine as substrates.
Topics: Air Pollutants; Animals; Biotransformation; Cocaine; Cytochrome P-450 Enzyme System; Formaldehyde; In Vitro Techniques; Male; Microsomes; Microsomes, Liver; Nasal Decongestants; Nasal Mucosa; Nicotine; Oils, Volatile; Oxygenases; Rats; Rats, Inbred F344; Solutions; Solvents; Substrate Specificity | 1983 |
Pharmacological dissection of receptor-associated and voltage-sensitive ionic channels involved in catecholamine release.
Topics: Acetylcholine; Adrenal Medulla; Animals; Catecholamines; Cattle; Cocaine; Electrolytes; Ethers; Imipramine; Ion Channels; Ionomycin; Membrane Potentials; Nicotine; Norepinephrine; Receptors, Cholinergic; Receptors, Nicotinic; Synaptic Transmission; Tetrodotoxin; Veratridine | 1983 |
Nonadrenergic nature of prazosin-resistant, sympathetic contraction in the dog mesenteric artery.
Topics: Animals; Cocaine; Dogs; Electric Stimulation; Female; Guanethidine; Hydroxydopamines; In Vitro Techniques; Male; Mesenteric Arteries; Nicotine; Norepinephrine; Oxidopamine; Prazosin; Quinazolines; Receptors, Adrenergic; Reserpine; Sympathetic Nervous System; Tetrodotoxin; Tyramine; Vasoconstriction | 1984 |
Role of training dose in discrimination of nicotine and related compounds by rats.
Topics: Alkaloids; Anabasine; Animals; Apomorphine; Azocines; Chlordiazepoxide; Cocaine; Discrimination, Psychological; Ganglionic Stimulants; Hexamethonium Compounds; Male; Mecamylamine; Nicotine; Oxotremorine; Picrotoxin; Quinolizines; Quipazine; Rats | 1984 |
Schedule-induced self injection of drugs.
Topics: Alcoholism; Animals; Cocaine; Conditioning, Operant; Corticosterone; Disease Models, Animal; Heroin Dependence; Humans; Nicotine; Nucleus Accumbens; Rats; Reinforcement Schedule; Substance-Related Disorders | 1984 |
[Formation of nicotine addiction in mongrel white rats].
Topics: Animals; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Humans; Male; Nicotine; Rats; Substance-Related Disorders; Time Factors | 1984 |
The discriminative stimulus properties of cocaine in the rhesus monkey.
Topics: Alkaloids; Animals; Cocaine; Dextroamphetamine; Discrimination, Psychological; Female; Macaca mulatta; Nicotine; Pentobarbital; Procaine; Self Stimulation | 1983 |
Control of behavior by intravenous nicotine injections in laboratory animals.
Topics: Animals; Behavior, Animal; Cocaine; Dogs; Dose-Response Relationship, Drug; Female; Injections, Intravenous; Male; Mecamylamine; Nicotine; Reinforcement Schedule; Saimiri; Smoking; Species Specificity | 1983 |
Nicotine self-administration in baboons.
Topics: Animals; Body Weight; Cocaine; Dose-Response Relationship, Drug; Food Deprivation; Nicotine; Papio; Reinforcement Schedule; Self Administration | 1983 |
Unique influences of ten drugs upon post-shock biting attack and pre-shock manual responding.
Topics: Aggression; Animals; Bites and Stings; Caffeine; Chlordiazepoxide; Chlorpromazine; Cocaine; Conditioning, Operant; Dextroamphetamine; Diazepam; Electroshock; Ethanol; Female; Humans; Male; Morphine; Nicotine; Phenobarbital; Saimiri | 1983 |
Uptake of [3H]-nicotine and [3H]-noradrenaline by cultured chromaffin cells.
Topics: Adrenal Medulla; Animals; Cattle; Cell Membrane; Cells, Cultured; Chromaffin System; Cocaine; Imipramine; Mecamylamine; Nicotine; Norepinephrine; Tetracaine | 1984 |
Predicting the dependence liability of stimulant drugs.
Topics: Animals; Antidepressive Agents; Appetite Depressants; Caffeine; Cocaine; Humans; Infusions, Parenteral; Male; Nicotine; Papio; Phenethylamines; Reinforcement, Psychology; Self Administration; Substance-Related Disorders | 1981 |
A comparison of nicotine and cocaine self-administration in the dog: fixed-ratio and progressive-ratio schedules of intravenous drug infusion.
Topics: Animals; Body Temperature; Cocaine; Conditioning, Operant; Dogs; Female; Heart Rate; Infusions, Parenteral; Male; Mecamylamine; Nicotine; Pupil; Self Administration | 1983 |
Maintenance of schedule-controlled behavior by intravenous injections of nicotine in squirrel monkeys.
Topics: Animals; Behavior, Animal; Cocaine; Drug Administration Schedule; Injections, Intravenous; Male; Mecamylamine; Nicotine; Saimiri | 1982 |
Development of behavioral sensitization to cocaine: influence of kappa opioid receptor agonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Benzeneacetamides; Cocaine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Locomotion; Male; Nicotine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Sensitivity and Specificity; Sodium Chloride | 1995 |
Antagonism of nicotine's action by cocaine analogs.
Topics: Animals; Brain; Cattle; Cocaine; Mecamylamine; Mice; Nicotine; Quinuclidinyl Benzilate; Structure-Activity Relationship | 1995 |
Caffeine and nicotine improve visual tracking by rats: a comparison with amphetamine, cocaine and apomorphine.
Topics: Amphetamine; Animals; Apomorphine; Caffeine; Cocaine; Dose-Response Relationship, Drug; Male; Nicotine; Psychomotor Performance; Rats; Rats, Sprague-Dawley | 1993 |
Influence of tetrodotoxin and calcium on changes in extracellular dopamine levels evoked by systemic nicotine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Calcium; Chromatography, High Pressure Liquid; Cocaine; Dextroamphetamine; Dopamine; Extracellular Space; Homovanillic Acid; Male; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1993 |
Maternal cocaine use without evidence of fetal exposure.
Topics: Adult; Cocaine; Cotinine; Female; Hair; Humans; Infant, Newborn; Meconium; Mothers; Narcotics; Nicotine; Placenta; Pregnancy; Smoking; Substance Abuse, Intravenous | 1994 |
Augmentation of the neurochemical effects of cocaine in the ventral striatum and medial prefrontal cortex following preexposure to amphetamine, but not nicotine: an in vivo microdialysis study.
Topics: Amphetamine; Animals; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Drug Synergism; Injections; Male; Microdialysis; Nicotine; Rats; Rats, Sprague-Dawley | 1994 |
Dopamine mechanisms play at best a small role in the nicotine discriminative stimulus.
Topics: Animals; Benzazepines; Cocaine; Cues; Discrimination Learning; Discrimination, Psychological; Dopamine; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Generalization, Stimulus; Male; Neurotransmitter Uptake Inhibitors; Nicotine; Piperazines; Rats; Receptors, Dopamine D1; Reinforcement Schedule; Spiperone | 1994 |
Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area.
Topics: Animals; Atropine; Cocaine; Dihydro-beta-Erythroidine; Dopamine; Food; Limbic System; Male; Microinjections; Motor Activity; Nicotine; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Self Administration; Tegmentum Mesencephali | 1994 |
History of in utero cocaine exposure in language-delayed children.
Topics: Case-Control Studies; Child, Preschool; Cocaine; Female; Humans; Language Development Disorders; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Substance-Related Disorders | 1994 |
[Alteration of cocaine, morphine and nicotine levels in serum of opiomaniacs treated by jie du ling].
Topics: Adolescent; Adult; Cocaine; Drugs, Chinese Herbal; Female; Humans; Male; Middle Aged; Morphine; Nicotine; Opioid-Related Disorders; Radioimmunoassay | 1994 |
Intrauterine cocaine, lead, and nicotine exposure and fetal growth.
Topics: Adult; Birth Weight; Body Height; Cephalometry; Cocaine; Cohort Studies; Cotinine; Demography; Embryonic and Fetal Development; Female; Humans; Infant, Newborn; Lead; Maternal-Fetal Exchange; Nicotine; Pregnancy; Regression Analysis | 1994 |
Drugs in ancient populations.
Topics: Cannabis; Cocaine; Egypt, Ancient; Germany; History, Ancient; Humans; Mummies; Nicotine; Peru; Sudan | 1993 |
Drugs in ancient populations.
Topics: Cocaine; Egypt, Ancient; History, Ancient; Humans; Mummies; Nicotine | 1993 |
Drugs in ancient populations.
Topics: Cannabis; Cocaine; Egypt, Ancient; History, Ancient; Humans; Mummies; Nicotine; Peru | 1993 |
The routine analysis of breast milk for drugs of abuse in a clinical toxicology laboratory.
Topics: Adult; Cocaine; Codeine; Ethanol; Female; Humans; Illicit Drugs; Infant, Newborn; Milk, Human; Neurotransmitter Uptake Inhibitors; Nicotine; Oxycodone; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Substance Abuse Detection; Substance-Related Disorders | 1994 |
Persistence of the ability of amphetamine preexposure to facilitate acquisition of cocaine self-administration.
Topics: Animals; Caffeine; Cocaine; Conditioning, Operant; Dextroamphetamine; Injections, Intravenous; Male; Nicotine; Rats; Rats, Sprague-Dawley; Self Administration | 1994 |
A method for simultaneous measurement of cocaine and nicotine in neonatal hair.
Topics: Cocaine; Cotinine; Female; Hair; Humans; Infant, Newborn; Maternal-Fetal Exchange; Nicotine; Pregnancy; Radioimmunoassay; Reagent Kits, Diagnostic; Smoking | 1994 |
[First identification of drugs in Egyptian mummies].
Topics: Cannabis; Cocaine; Egypt; Humans; Mummies; Nicotine; Pharmaceutical Preparations | 1993 |
First identification of drugs in Egyptian mummies.
Topics: Artifacts; Cocaine; Egypt; Humans; Mummies; Nicotine; Pharmaceutical Preparations; Plants | 1993 |
First identification of drugs in Egyptian mummies.
Topics: Artifacts; Cocaine; Egypt; Humans; Mummies; Nicotine; Pharmaceutical Preparations | 1993 |
First identification of drugs in Egyptian mummies.
Topics: Artifacts; Cannabis; Cocaine; Dronabinol; Egypt; Humans; Mummies; Nicotiana; Nicotine; Pharmaceutical Preparations; Plants, Toxic | 1993 |
First identification of drugs in Egyptian mummies.
Topics: Artifacts; Bone and Bones; Cannabis; Cocaine; Dronabinol; Egypt; Hair; Humans; Mummies; Nicotine; Pharmaceutical Preparations | 1993 |
Nicotine reinforcement in rats with histories of cocaine self-administration.
Topics: Animals; Cocaine; Male; Nicotine; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Sodium Chloride | 1995 |
Extensive pulmonary haemorrhage in an Egyptian mummy.
Topics: Adult; Cocaine; Dronabinol; Egypt; Hemorrhage; Hemosiderin; Humans; Lung; Lung Diseases; Male; Mummies; Nicotine; Trace Elements | 1995 |
5-fluoronicotine, noranhydroecgonine, and pyridyl-methylpyrrolidine release acetylcholine and biogenic amines in rat cortex in vivo.
Topics: Acetylcholine; Animals; Biogenic Amines; Cerebral Cortex; Cocaine; Male; Microdialysis; Nicotine; Nicotinic Agonists; Pyridines; Pyrrolidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 1995 |
Drugs institute gives grant for cocaine vaccine.
Topics: Animals; Cocaine; Drug Industry; Financing, Government; Humans; National Institutes of Health (U.S.); Nicotine; Rats; Research Support as Topic; Substance-Related Disorders; United States; Vaccines | 1996 |
Differential role of delta-opioid receptors in the development and expression of behavioral sensitization to cocaine.
Topics: Animals; Behavior, Animal; Cocaine; Male; Motor Activity; Naltrexone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta | 1996 |
Common neural substrates for the addictive properties of nicotine and cocaine.
Topics: Amygdala; Animals; Brain; Brain Mapping; Cocaine; DNA; Neostriatum; Neurons; Nicotine; Nucleus Accumbens; Opioid-Related Disorders; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Reinforcement, Psychology; Self Administration; Substance-Related Disorders; Transcription Factor AP-1 | 1997 |
Prevalence and demographic correlates of symptoms of last year dependence on alcohol, nicotine, marijuana and cocaine in the U.S. population.
Topics: Adolescent; Adult; Age Factors; Aged; Alcoholism; Cocaine; Cross-Sectional Studies; Ethnicity; Female; Humans; Incidence; Male; Marijuana Abuse; Middle Aged; Nicotine; Sex Factors; Smoking; Substance-Related Disorders; United States | 1997 |
Behavioural and neurochemical characteristics of phentermine and fenfluramine administered separately and as a mixture in rats.
Topics: Amphetamine; Animals; Cocaine; Discrimination Learning; Dopamine; Dopamine Uptake Inhibitors; Drug Interactions; Fenfluramine; Illicit Drugs; Male; Microdialysis; Nicotine; Nucleus Accumbens; Phentermine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents | 1997 |
Serotonergic receptors modify the voluntary intake of alcohol and morphine but not of cocaine and nicotine by rats.
Topics: Alcohol Drinking; Animals; Choice Behavior; Cocaine; Fluvoxamine; Male; Morphine; Narcotics; Nicotine; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists | 1997 |
Nicotine and heroin augment cocaine-induced dopamine overflow in nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Heroin; Homovanillic Acid; Male; Microdialysis; Narcotics; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats; Rats, Wistar | 1997 |
Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Binding Sites; Carrier Proteins; Cocaine; Conditioning, Operant; Dopamine; Dopamine Plasma Membrane Transport Proteins; Homovanillic Acid; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Microdialysis; Motor Activity; Nerve Tissue Proteins; Nicotine; Nucleus Accumbens; Patch-Clamp Techniques; Receptors, Nicotinic; Second Messenger Systems; Substantia Nigra; Ventral Tegmental Area | 1998 |
Repeated administration of cocaine, nicotine and ethanol: effects on preprodynorphin, preprotachykinin A and preproenkephalin mRNA expression in the dorsal and the ventral striatum of the rat.
Topics: Animals; Body Weight; Cocaine; Corpus Striatum; Drug Administration Schedule; Dynorphins; Enkephalins; Ethanol; In Situ Hybridization; Injections, Subcutaneous; Male; Nicotine; Nucleus Accumbens; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tachykinins | 1998 |
Conditioning factors in drug abuse: can they explain compulsion?
Topics: Alcohols; Anesthetics, Local; Cocaine; Conditioning, Psychological; Disruptive, Impulse Control, and Conduct Disorders; Ganglionic Stimulants; Humans; Learning; Narcotics; Nicotine; Substance-Related Disorders | 1998 |
Fetal nicotine or cocaine exposure: which one is worse?
Topics: Cocaine; Dopamine Uptake Inhibitors; Embryonic and Fetal Development; Female; Fetus; Ganglionic Stimulants; Humans; Infant Mortality; Infant, Newborn; Infant, Newborn, Diseases; Neurotransmitter Agents; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Nicotinic; Risk Factors; Smoking; Substance-Related Disorders; Sudden Infant Death | 1998 |
Sex differences in cocaine- and nicotine-induced antinociception in the rat.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Cocaine; Female; Hot Temperature; Male; Nicotine; Nicotinic Agonists; Nociceptors; Pain; Rats; Rats, Sprague-Dawley; Sex Characteristics | 1998 |
5-HT4 receptor antagonism does not affect motor and reward mechanisms in the rat.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Dioxanes; Hyperkinesis; Male; Motor Activity; Nicotine; Piperidines; Rats; Rats, Sprague-Dawley; Self Stimulation; Serotonin Antagonists | 1998 |
Behavioral effects of nicotine, amphetamine and cocaine under a fixed-interval schedule of food reinforcement in rats chronically exposed to caffeine.
Topics: Amphetamine; Animals; Caffeine; Central Nervous System Stimulants; Cocaine; Drinking; Food-Drug Interactions; Male; Nicotine; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Substance-Related Disorders | 1998 |
Effect of ventral tegmental 6-hydroxydopamine lesions on the locomotor stimulant action of nicotine in rats.
Topics: Amphetamine; Animals; Autoradiography; Carrier Proteins; Caudate Nucleus; Cocaine; Denervation; Dopamine; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Neurons; Nicotine; Nucleus Accumbens; Oxidopamine; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Scopolamine; Tegmentum Mesencephali; Time Factors | 1998 |
Induction of rat hepatic cytochromes P450 by toxic ingredients in plants: lack of correlation between toxicity and inductive activity.
Topics: Aconitine; Amygdalin; Animals; Aryl Hydrocarbon Hydroxylases; Body Weight; Cocaine; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Digitonin; Enzyme Induction; Male; Microsomes, Liver; Nicotine; Organ Size; Plants; Rats; Rats, Wistar; Solanine; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Testosterone; Toxins, Biological | 1998 |
Acquisition of nicotine discrimination and discriminative stimulus effects of nicotine in rats chronically exposed to caffeine.
Topics: Amphetamine; Analysis of Variance; Animals; Caffeine; Cocaine; Discrimination Learning; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Piperazines; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Thiazepines | 1999 |
Effects of cocaine, nicotine, dizocipline and alcohol on mice locomotor activity: cocaine-alcohol cross-sensitization involves upregulation of striatal dopamine transporter binding sites.
Topics: Animals; Binding Sites; Carrier Proteins; Cocaine; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Ethanol; Excitatory Amino Acid Antagonists; GABA Agonists; Ganglionic Stimulants; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; Nerve Tissue Proteins; Nicotine; Up-Regulation | 1999 |
AND and AND-OR drug mixture discriminations in rats: generalization to single drugs and drug mixtures.
Topics: Animals; Anti-Anxiety Agents; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Cocaine; Dextroamphetamine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Combinations; Ethanol; Generalization, Response; Male; Midazolam; Nicotine; Nicotinic Agonists; Rats | 1999 |
Pharmacological characterization of nicotine's interaction with cocaine and cocaine analogs.
Topics: Animals; Body Temperature; Bupropion; Cocaine; Discrimination, Psychological; Female; Male; Membrane Potentials; Mice; Mice, Inbred ICR; Molecular Structure; Motor Activity; Nicotine; Oocytes; Pain; Piperazines; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Recombinant Proteins; Seizures; Structure-Activity Relationship; Tropanes; Xenopus laevis | 1999 |
Deposition of [3H]cocaine, [3H]nicotine, and [3H]flunitrazepam in mouse hair melanosomes after systemic administration.
Topics: Animals; Area Under Curve; Autoradiography; Cocaine; Flunitrazepam; Hair; Melanosomes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nicotine; Pigmentation; Sebaceous Glands; Skin | 1999 |
Differences in receptor system participation between nicotine- and cocaine-induced dopamine overflow in nucleus accumbens.
Topics: Animals; Benzazepines; Cocaine; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Male; Microdialysis; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Nicotinic | 1999 |
Regulation of intravenously self-administered nicotine in rats.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Infusions, Intravenous; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Self Administration | 1999 |
Pharmacokinetics of radiotracers in human plasma during positron emission tomography.
Topics: Benzazepines; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cocaine; Dihydroxyphenylalanine; Dopamine Antagonists; Drug Interactions; Fluorine Radioisotopes; Humans; Nicotine; Raclopride; Radiopharmaceuticals; Selegiline; Tomography, Emission-Computed | 1999 |
Periadolescent nicotine exposure reduces cocaine reward in adult mice.
Topics: Age Factors; Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Locomotion; Male; Mice; Mice, Inbred C57BL; Nicotine; Reinforcement, Psychology; Reward; Self Administration; Sensitivity and Specificity; Weight Gain | 1999 |
The effect of cotinine on nicotine- and cocaine-induced dopamine release in the nucleus accumbens.
Topics: Alkaloids; Animals; Azocines; Brain Chemistry; Cocaine; Cotinine; Dopamine; Male; Nicotine; Nucleus Accumbens; Quinolizines; Rats; Rats, Sprague-Dawley | 1999 |
Assessment of nicotinic acetylcholine receptor subunit contributions to nicotine self-administration in mutant mice.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Injections, Intravenous; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nicotine; Nicotinic Agonists; Receptors, Nicotinic; Reinforcement Schedule; Reinforcement, Psychology; Self Administration | 1999 |
Cocaine-seeking produced by experimenter-administered drug injections: dose-effect relationships in rats.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Dronabinol; Hallucinogens; Male; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reinforcement Schedule | 1999 |
Striatal application of nicotine, but not of lobeline, attenuates dopamine release in freely moving rats.
Topics: Aconitine; Animals; Cocaine; Corpus Striatum; Dopamine; Kinetics; Lobeline; Male; Mecamylamine; Microdialysis; Nerve Endings; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2000 |
Dopamine modulates acute responses to cocaine, nicotine and ethanol in Drosophila.
Topics: Animals; Behavior, Animal; Cocaine; Dopamine; Drosophila; Ethanol; Male; Nicotine | 2000 |
Stereoselective inhibition of dopaminergic activity by gamma vinyl-GABA following a nicotine or cocaine challenge: a PET/microdialysis study.
Topics: Animals; Cocaine; Dopamine; Male; Microdialysis; Nicotine; Nucleus Accumbens; Papio; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tomography, Emission-Computed; Vigabatrin | 2000 |
Asymmetric generalization between the discriminative stimulus effects of nicotine and cocaine.
Topics: Animals; Cocaine; Discrimination Learning; Discrimination, Psychological; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Generalization, Stimulus; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Synaptic Transmission | 1999 |
Effects of methyllycaconitine (MLA), an alpha 7 nicotinic receptor antagonist, on nicotine- and cocaine-induced potentiation of brain stimulation reward.
Topics: Aconitine; Animals; Cocaine; Dopamine Uptake Inhibitors; Hypothalamic Area, Lateral; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reward; Ventral Tegmental Area | 2000 |
The effects of cocaine and nicotine on amino acid transport across the human placental cotyledon perfused in vitro.
Topics: Amino Acids; Biological Transport; Cocaine; Female; Humans; Nicotine; Perfusion; Placenta; Pregnancy | 2000 |
Tone abnormalities are associated with maternal cigarette smoking during pregnancy in in utero cocaine-exposed infants.
Topics: Cocaine; Confounding Factors, Epidemiologic; Cotinine; Female; Humans; Infant; Infant, Newborn; Logistic Models; Male; Meconium; Muscle Hypertonia; Nervous System Diseases; Neurologic Examination; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Smoking | 2000 |
Substance use measures among women in early pregnancy.
Topics: Cannabinoids; Cocaine; Cocaine-Related Disorders; Cotinine; Female; Gestational Age; Hair; Humans; Marijuana Abuse; Nicotine; Pregnancy; Smoking; Substance Abuse Detection | 2000 |
Stimulation of in vivo dopamine transmission in the bed nucleus of stria terminalis by reinforcing drugs.
Topics: Analysis of Variance; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Ethanol; Extracellular Space; Illicit Drugs; Male; Microdialysis; Morphine; Nicotine; Piperazines; Rats; Rats, Sprague-Dawley; Septal Nuclei; Synaptic Transmission | 2000 |
Synergistic interactions between nicotine and cocaine or methylphenidate depend on the dose of dopamine transporter inhibitor.
Topics: Animals; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 2000 |
Changes in the ambulatory activity and discriminative stimulus effects of psychostimulant drugs in rats chronically exposed to caffeine: effect of caffeine dose.
Topics: Amphetamine; Animals; Caffeine; Cocaine; Cotinine; Discrimination Learning; Dose-Response Relationship, Drug; Generalization, Psychological; Male; Motor Activity; Nicotine; Rats; Rats, Sprague-Dawley | 2000 |
Cannabinoid CB1 receptor knockout mice fail to self-administer morphine but not other drugs of abuse.
Topics: Amphetamine; Animals; Behavior, Addictive; Cannabinoids; Cocaine; Dopamine Uptake Inhibitors; Male; Mice; Mice, Knockout; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Receptors, Cannabinoid; Receptors, Drug; Reward | 2001 |
Nicotine receptor inactivation decreases sensitivity to cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Cholinergic Fibers; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Knockout; Neurons; Nicotine; Nucleus Accumbens; Receptors, Nicotinic | 2001 |
Gains in oral tests.
Topics: Administration, Oral; Cocaine; Cocaine-Related Disorders; Diagnostic Tests, Routine; HIV Infections; HIV-1; Humans; Insurance, Life; Nicotine; Tobacco Use Disorder | 1999 |
Inhibition of the serotonin 5-HT3 receptor by nicotine, cocaine, and fluoxetine investigated by rapid chemical kinetic techniques.
Topics: Animals; Binding Sites; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Electrophysiology; Fluoxetine; Kinetics; Mice; Nicotine; Patch-Clamp Techniques; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Tumor Cells, Cultured | 2001 |
Combined effects of cocaine and nicotine on cardiovascular performance in a canine model.
Topics: Animals; Cardiovascular System; Cocaine; Dogs; Drug Combinations; Ganglionic Stimulants; Hemodynamics; Models, Cardiovascular; Nicotine; Substance-Related Disorders; Vasoconstrictor Agents | 2001 |
Effects of strain, behavior and age on the self-administration of ethanol, nicotine, cocaine and morphine by two rat strains.
Topics: Administration, Oral; Aging; Animals; Behavior, Animal; Cocaine; Ethanol; Male; Morphine; Nicotine; Rats; Rats, Inbred BN; Rats, Inbred Strains; Rats, Inbred WKY; Self Administration | 2001 |
3H-nicotine, 3H-flunitrazepam, and 3H-cocaine incorporation into melanin: a model for the examination of drug-melanin interactions.
Topics: Cocaine; Drug Interactions; Flunitrazepam; GABA Modulators; Ganglionic Stimulants; Hair; Humans; Melanins; Narcotics; Nicotine; Polymers; Tritium | 2001 |
GABA mechanisms in the pedunculopontine tegmental nucleus influence particular aspects of nicotine self-administration selectively in the rat.
Topics: Animals; Brain Stem; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; GABA Agonists; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Long-Evans; Reinforcement Schedule; Self Administration; Tegmentum Mesencephali | 2001 |
Stimulation of endorphin neurotransmission in the nucleus accumbens by ethanol, cocaine, and amphetamine.
Topics: Amphetamine; Animals; Cocaine; Endorphins; Ethanol; Extracellular Space; Male; Microdialysis; Motivation; Nicotine; Nucleus Accumbens; Radioimmunoassay; Rats; Rats, Long-Evans; Reward; Synaptic Transmission | 2001 |
Rats prefer cocaine over nicotine in a two-lever self-administration choice test.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Infusion Pumps; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration; Tobacco Use Disorder | 2002 |
Pharmacological manipulations of the pedunculopontine tegmental nucleus in the rat reduce self-administration of both nicotine and cocaine.
Topics: Animals; Behavior, Animal; Carbachol; Central Nervous System Agents; Cocaine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Nicotine; Rats; Rats, Long-Evans; Scopolamine; Self Administration; Substance-Related Disorders; Tegmentum Mesencephali | 2002 |
Systemic administration of 1R,4S-4-amino-cyclopent-2-ene-carboxylic acid, a reversible inhibitor of GABA transaminase, blocks expression of conditioned place preference to cocaine and nicotine in rats.
Topics: 4-Aminobutyrate Transaminase; Animals; Cocaine; Conditioning, Operant; Cyclopentanes; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Nicotine; Rats; Rats, Sprague-Dawley | 2002 |
Psychostimulant-induced behavioral sensitization depends on nicotinic receptor activation.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Association Learning; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Uptake Inhibitors; In Vitro Techniques; Male; Mecamylamine; Motivation; Motor Activity; Neuronal Plasticity; Neurons; Nicotine; Nicotinic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Nicotinic | 2002 |
Receptors in the ventral tegmental area mediating nicotine-induced dopamine release in the nucleus accumbens.
Topics: Animals; Atropine; Benzazepines; Cocaine; Dizocilpine Maleate; Dopamine; Kinetics; Male; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Muscarinic; Receptors, Neurotransmitter; Receptors, Nicotinic; Ventral Tegmental Area | 2002 |
Enhancement of cocaine-seeking behavior by repeated nicotine exposure in rats.
Topics: Animals; Behavior, Addictive; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Injections, Intravenous; Injections, Subcutaneous; Male; Nicotine; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Time Factors | 2002 |
Neural degeneration following chronic stimulant abuse reveals a weak link in brain, fasciculus retroflexus, implying the loss of forebrain control circuitry.
Topics: Amphetamine; Animals; Brain; Central Nervous System Stimulants; Cocaine; Habenula; Haplorhini; Humans; Medial Forebrain Bundle; Nerve Degeneration; Neuroanatomy; Nicotine; Perforant Pathway; Prosencephalon; Rats | 2002 |
Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine.
Topics: Animals; Arachidonic Acids; Binding Sites; Brain; Cannabinoid Receptor Modulators; Cannabinoids; Cocaine; Endocannabinoids; Ethanol; Glycerides; In Situ Hybridization; Male; Nicotine; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; RNA, Messenger; Substance-Related Disorders | 2002 |
The mGluR5 antagonist MPEP reduces the conditioned rewarding effects of cocaine but not other drugs of abuse.
Topics: Amphetamine; Animals; Behavior, Animal; Choice Behavior; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Antagonists; Illicit Drugs; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Narcotics; Nicotine; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reward | 2003 |
Evidence of cross-tolerance between behavioural effects of nicotine and cocaine in mice.
Topics: Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Drug Tolerance; Male; Mice; Motor Activity; Nicotine; Receptors, Dopamine D2 | 2003 |
Dopaminergic and cholinergic involvement in the discriminative stimulus effects of nicotine and cocaine in rats.
Topics: Acetylcholine; Animals; Cholinergic Agonists; Cocaine; Conditioning, Operant; Discrimination, Psychological; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Flupenthixol; Generalization, Stimulus; Male; Mecamylamine; Muscarinic Agonists; Nicotine; Nicotinic Antagonists; Pilocarpine; Rats; Rats, Sprague-Dawley | 2003 |
Prenatal cocaine and/or nicotine exposure produces depression and anxiety in aging rats.
Topics: Aging; Animals; Anxiety; Cocaine; Depression; Female; Male; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Sex Characteristics | 2003 |
Baclofen antagonizes nicotine-, cocaine-, and morphine-induced dopamine release in the nucleus accumbens of rat.
Topics: Animals; Baclofen; Cocaine; Dopamine; Dose-Response Relationship, Drug; Extracellular Fluid; GABA Agonists; GABA-B Receptor Agonists; Male; Microdialysis; Morphine; Neural Pathways; Nicotine; Nucleus Accumbens; Rats; Receptors, GABA-B; Reward; Substance-Related Disorders; Synaptic Transmission; Up-Regulation | 2003 |
Effects of continuous nicotine infusion on nicotine self-administration in rats: relationship between continuously infused and self-administered nicotine doses and serum concentrations.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Ganglionic Stimulants; Infusions, Intravenous; Male; Nicotine; Rats; Rats, Sprague-Dawley; Self Administration | 2003 |
Retention of sequential drug discriminations under fixed-interval schedules for long time periods without training.
Topics: Animals; Behavior, Animal; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Chlordiazepoxide; Cocaine; Columbidae; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Dronabinol; Generalization, Psychological; Male; Morphine; Nicotine; Pentobarbital; Reinforcement Schedule | 2003 |
Action of some ganglion-stimulating substances on the secretion of saliva from the submandibular gland.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adrenal Medulla; Animals; Autonomic Agents; Cats; Choline; Cocaine; Ganglia, Autonomic; Nicotine; Pilocarpine; Saliva; Salivation; Submandibular Gland; Superior Cervical Ganglion | 1962 |
The pressor response of the spinal cat to different group of ganglion-stimulating agents.
Topics: Animals; Atropine; Autonomic Agents; Blood Pressure; Cats; Cocaine; Humans; Methadone; Nicotine; Vasoconstrictor Agents | 1963 |
GANGLIONIC ACTIONS OF MUSCARINIC SUBSTANCES.
Topics: Animals; Atropine; Autonomic Nervous System; Cats; Cholinergic Agents; Cocaine; Ganglia; Ganglia, Autonomic; Ganglionic Blockers; Hexamethonium Compounds; Methadone; Morphine; Nicotine; Nictitating Membrane; Parasympathomimetics; Pharmacology; Research | 1963 |
THE ISOLATED PILOMOTOR MUSCLES AS AN IN VITRO PREPARATION.
Topics: Acetylcholine; Amphetamine; Amphetamines; Animals; Atropine; Bradykinin; Bretylium Compounds; Cats; Cocaine; Epinephrine; Guanethidine; Hair; Hexamethonium Compounds; Histamine; In Vitro Techniques; Indoles; Isoproterenol; Muscle, Smooth; Nicotine; Nictitating Membrane; Norepinephrine; Phenoxybenzamine; Phentolamine; Physostigmine; Research; Reserpine; Serotonin; Skin; Tyramine | 1963 |
MATURATION OF THE ELECTROCORTICOGRAM AND BEHAVIOUR IN THE KITTEN AND GUINEA-PIG AND THE EFFECT OF SOME SYMPATHOMIMETIC AMINES.
Topics: Animals; Atropine; Cats; Cocaine; Dopamine; Electroencephalography; Ephedrine; Epinephrine; Female; Guinea Pigs; Methoxamine; Nicotine; Pentobarbital; Pharmacology; Phenylephrine; Physostigmine; Research; Scopolamine; Sympathomimetics; Tyramine | 1963 |
STIMULANT ACTIONS OF VOLATILE ANAESTHETICS ON SMOOTH MUSCLE.
Topics: Acetylcholine; Anesthetics; Animals; Anti-Allergic Agents; Central Nervous System Stimulants; Chloroform; Cocaine; Epinephrine; Ether; Ethers; Guinea Pigs; Halothane; Hexamethonium Compounds; Histamine; Histamine H1 Antagonists; Ileum; Muscle Contraction; Muscle, Smooth; Nicotine; Pharmacology; Pyrilamine; Research; Trichloroethylene | 1964 |
PARTICIPATION OF AN UNUSUAL GANGLIONIC PATHWAY IN THE MEDIATION OF THE PRESSOR EFFECT OF PHYSOSTIGMINE IN THE RAT.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Autonomic Agents; Blood Pressure; Cocaine; Dimethylphenylpiperazinium Iodide; Ganglionic Stimulants; Hexamethonium Compounds; Negotiating; Nicotine; Norepinephrine; Pharmacology; Physostigmine; Piperazines; Rats; Research; Vasoconstrictor Agents | 1964 |
[STUDIES ON THE CAUSES OF POTASSIUM INCREASE IN THE BLOOD FOLLOWING NICOTINE AND CALCIUM ADMINISTRATION].
Topics: Adrenalectomy; Calcium; Calcium, Dietary; Cats; Cocaine; Epinephrine; Hyperkalemia; Nicotine; Pharmacology; Potassium; Research | 1964 |
THE RELEASE OF CATECHOLAMINES FROM THE ISOLATED CAT HEART BY MEPHENTERMINE.
Topics: Catecholamines; Cats; Cocaine; Fluorometry; Heart; Intestines; Isoproterenol; Mephentermine; Metabolism; Muscle Relaxants, Central; Myocardium; Nicotine; Pharmacology; Rabbits; Research; Reserpine | 1964 |
[Potentiation with adrenalin of the central effect of hydroxydione, cocaine, strychnine and nicotine].
Topics: Central Nervous System; Cocaine; Epinephrine; Nervous System; Nicotine; Pregnanediones; Strophanthins; Strychnine | 1961 |
Dopamine responsiveness to drugs of abuse: A shell-core investigation in the nucleus accumbens of the mouse.
Topics: Amphetamine; Anesthetics, Local; Animals; Calbindins; Central Nervous System Depressants; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine; Ethanol; Extracellular Space; Illicit Drugs; Immunohistochemistry; Male; Mice; Microdialysis; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Nucleus Accumbens; S100 Calcium Binding Protein G; Substance-Related Disorders; Time Factors | 2003 |
Selective psychostimulant sensitization by food restriction: differential changes in accumbens shell and core dopamine.
Topics: Amidines; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dialysis; Dopamine; Dose-Response Relationship, Drug; Food; Male; Morphine; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Time Factors; Vasoconstrictor Agents | 2003 |
Metabotropic glutamate 5 receptor antagonist MPEP decreased nicotine and cocaine self-administration but not nicotine and cocaine-induced facilitation of brain reward function in rats.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Nicotine; Nicotinic Agonists; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reward; Tobacco Use Disorder | 2003 |
Prolonged nicotine dependence associated with extended access to nicotine self-administration in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Ganglionic Stimulants; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Self Administration; Substance Withdrawal Syndrome; Time Factors; Tobacco Use Disorder | 2004 |
[Comparative effects of acetylcholine, atropine, cocaine, eserine and nicotine on the heart of some salt-water fish].
Topics: Acetylcholine; Animals; Atropine; Cocaine; Heart; Nicotine; Physostigmine | 1951 |
[Paper partition microchromatography of alkaloids and of various biological nitrogenous bases. III. Examples of the separation of various alkaloids by the acid solvent phase technic (atropine, cocaine, nicotine, sparteine, strychnine and corynanthine fami
Topics: Alkaloids; Atropine; Cocaine; Nicotine; Paper; Solvents; Sparteine; Strychnine; Yohimbine | 1951 |
Chronic nicotine differentially alters cocaine-induced locomotor activity in adolescent vs. adult male and female rats.
Topics: Age Factors; Animals; Cocaine; Dose-Response Relationship, Drug; Female; Male; Motor Activity; Nicotine; Rats; Rats, Sprague-Dawley; Sex Characteristics; Stereotyped Behavior | 2004 |
Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain.
Topics: Adrenergic Uptake Inhibitors; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzazepines; Brain; Caffeine; Central Nervous System Stimulants; Cocaine; Desipramine; Dopamine Antagonists; Dronabinol; Enzyme Activation; Fluoxetine; Immunohistochemistry; Male; Mice; Mitogen-Activated Protein Kinases; Morphine; Muscarinic Antagonists; Neurons; Nicotine; Nicotinic Agonists; Scopolamine; Selective Serotonin Reuptake Inhibitors | 2004 |
Lobeline analogs with enhanced affinity and selectivity for plasmalemma and vesicular monoamine transporters.
Topics: Aconitine; Animals; Biological Transport; Carrier Proteins; Cells, Cultured; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ganglionic Stimulants; Humans; Iodine Radioisotopes; Kinetics; Lobeline; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuropeptides; Nicotine; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Rubidium; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters; Tetrabenazine; Tritium; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2004 |
Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotine-triggered relapse to nicotine-seeking.
Topics: Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Injections, Intravenous; Male; Motor Activity; Nicotine; Psychomotor Performance; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Secondary Prevention; Self Administration; Substance-Related Disorders | 2004 |
Screening for drugs of abuse in hair with ion spray LC-MS-MS.
Topics: Amphetamines; Anti-Anxiety Agents; Central Nervous System Stimulants; Chromatography, Liquid; Cocaine; Cotinine; Diazepam; Dopamine Uptake Inhibitors; Drug Overdose; Flunitrazepam; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Morphine; Morphine Derivatives; Narcotics; Nicotine; Nicotinic Agonists; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection | 2004 |
Acetaldehyde enhances acquisition of nicotine self-administration in adolescent rats.
Topics: Acetaldehyde; Adolescent; Age Factors; Aging; Animals; Brain; Brain Chemistry; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Humans; Male; Nicotiana; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reinforcement, Psychology; Reward; Self Administration; Tobacco Use Disorder | 2005 |
Effects of environmental enrichment on behavior and dopamine transporter function in medial prefrontal cortex in adult rats prenatally treated with cocaine.
Topics: Animals; Behavior, Animal; Brain Chemistry; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Electrochemistry; Electrophysiology; Environment; Female; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microinjections; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Ovariectomy; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Long-Evans; Social Behavior | 2004 |
The metabotropic glutamate receptor 5 antagonist MPEP decreased break points for nicotine, cocaine and food in rats.
Topics: Animals; Cocaine; Excitatory Amino Acid Antagonists; Food; Male; Motivation; Nicotine; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reinforcement, Psychology; Self Administration | 2005 |
Effects of nicotinic and NMDA receptor channel blockers on intravenous cocaine and nicotine self-administration in mice.
Topics: Animals; Behavior, Addictive; Cocaine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Infusions, Intravenous; Male; Mice; Nicotine; Nicotinic Antagonists; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Self Administration | 2005 |
Periadolescent nicotine exposure causes heterologous sensitization to cocaine reinforcement.
Topics: Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Motor Activity; Nicotine; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Time Factors | 2005 |
Concurrent measures of feeding and locomotion in rats.
Topics: Animals; Cocaine; Diet; Dopamine Uptake Inhibitors; Drinking; Eating; Feeding Behavior; Male; Motor Activity; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Stereotyped Behavior | 2005 |
Mu-opioid receptor and CREB activation are required for nicotine reward.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Blotting, Northern; Blotting, Western; Brain; Cell Count; Cocaine; Conditioning, Operant; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Immunohistochemistry; Immunoprecipitation; Mice; Mice, Inbred C57BL; Mice, Knockout; Naloxone; Narcotic Antagonists; Neurons; Nicotine; Phosphorylation; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; Reward; RNA, Messenger; Time Factors; Tobacco Use Disorder | 2005 |
moody encodes two GPCRs that regulate cocaine behaviors and blood-brain barrier permeability in Drosophila.
Topics: Alternative Splicing; Animals; Behavior, Animal; Blood-Brain Barrier; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drosophila melanogaster; Drosophila Proteins; Drug Tolerance; Male; Motor Activity; Neuroglia; Nicotine; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Substance-Related Disorders | 2005 |
Prenatal cocaine alone and combined with nicotine alters ANG II and IGF-1 induced left atrial contractions in aging male offspring.
Topics: Aging; Angiotensin II; Animals; Atrial Function, Left; Cardiotonic Agents; Cocaine; Female; Heart Atria; Insulin-Like Growth Factor I; Male; Myocardial Contraction; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 2005 |
A high-performance thin-layer chromatographic technique to screen cocaine in urine samples.
Topics: Anesthetics, Local; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Cocaine; Dopamine Uptake Inhibitors; Forensic Medicine; Ganglionic Stimulants; Humans; Nicotine; Substance Abuse Detection | 2006 |
Behavioral teratogenicity induced by nonforced maternal nicotine consumption.
Topics: Animals; Association Learning; Attention Deficit and Disruptive Behavior Disorders; Behavior, Animal; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Electroshock; Fear; Female; Mice; Mice, Inbred C57BL; Motor Activity; Nicotine; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Sex Factors | 2007 |
Alcohol-, nicotine-, and cocaine-evoked release of morphine from invertebrate ganglia: model system for screening drugs of abuse.
Topics: Animals; Cocaine; Drug Evaluation, Preclinical; Ethanol; Ganglia, Invertebrate; Illicit Drugs; In Vitro Techniques; Morphine; Mytilus edulis; Nephropidae; Nicotine | 2006 |
Behavioral disinhibition requires dopamine receptor activation.
Topics: Amphetamine; Animals; Behavior, Animal; Benzazepines; Cocaine; Desipramine; Dose-Response Relationship, Drug; Impulsive Behavior; Male; Nicotine; Piperazines; Rats; Rats, Wistar; Receptors, Dopamine; Serotonin | 2006 |
Electrolytic lesions of the nucleus accumbens enhance locomotor sensitization to nicotine in rats.
Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrolysis; Locomotion; Male; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats; Rats, Long-Evans | 2006 |
A validation of event-related FMRI comparisons between users of cocaine, nicotine, or cannabis and control subjects.
Topics: Adult; Brain; Brain Mapping; Cocaine; Cocaine-Related Disorders; Dronabinol; Evoked Potentials; Female; Frontal Lobe; Gyrus Cinguli; Hemodynamics; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Marijuana Abuse; Middle Aged; Nicotine; Psychomotor Performance; Regional Blood Flow; Reproducibility of Results; ROC Curve; Tobacco Use Disorder | 2006 |
Effect of morphine on locomotor activity and striatal monoamine metabolism in nicotine-withdrawn mice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Biogenic Monoamines; Central Nervous System Stimulants; Cocaine; Dopamine; Drug Interactions; Male; Mice; Morphine; Motor Activity; Narcotics; Neostriatum; Nicotine; Norepinephrine; Nucleus Accumbens; Serotonin; Substance Withdrawal Syndrome | 2006 |
Alcohol-, nicotine-, and cocaine-evoked release of morphine from human white blood cells: substances of abuse actions converge on endogenous morphine release.
Topics: Alcohols; Cocaine; Dose-Response Relationship, Drug; Humans; Iodine Radioisotopes; Leukocytes; Leukocytes, Mononuclear; Morphine; Neutrophils; Nicotine; Radioimmunoassay; Substance-Related Disorders | 2006 |
Substance use and related problems: a study on the abuse of recreational and not recreational drugs in Northern Italy.
Topics: Accidents, Traffic; Adult; Alcoholism; Amphetamines; Anxiety; Crack Cocaine; Depression; Female; Hallucinogens; Heroin; Humans; Italy; Ketamine; Male; Marijuana Abuse; Nicotine; Opium; Sleep Wake Disorders; Substance-Related Disorders; Surveys and Questionnaires | 2006 |
Tranylcypromine enhancement of nicotine self-administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Benzazepines; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrochemistry; Half-Life; Male; Microdialysis; Monoamine Oxidase Inhibitors; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reward; Self Administration; Tranylcypromine | 2007 |
Sweat testing in addicts under methadone treatment: an Italian experience.
Topics: Aged; Aged, 80 and over; Caffeine; Central Nervous System Stimulants; Cocaine; Cotinine; Dopamine Uptake Inhibitors; Female; Forensic Toxicology; Ganglionic Stimulants; Gas Chromatography-Mass Spectrometry; Hair; Heroin Dependence; Humans; Italy; Male; Methadone; Middle Aged; Narcotics; Nicotine; Pyrrolidines; Sweat | 2008 |
Ultraperformance liquid chromatography-tandem mass spectrometry analysis of stimulatory drugs of abuse in wastewater and surface waters.
Topics: Amphetamine; Caffeine; Chromatography, High Pressure Liquid; Cocaine; Illicit Drugs; Nicotine; Rivers; Sewage; Spain; Tandem Mass Spectrometry; Time; Water Pollutants, Chemical | 2007 |
Modafinil evokes striatal [(3)H]dopamine release and alters the subjective properties of stimulants.
Topics: Amphetamine; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Male; Modafinil; Nicotine; Nomifensine; Rats; Rats, Sprague-Dawley | 2007 |
Detection of cocaine in the airborne particles of the Italian cities Rome and Taranto.
Topics: Aerosols; Air; Air Pollutants; Caffeine; Cities; Cocaine; Dust; Environmental Monitoring; Italy; Mass Spectrometry; Nicotine; Particle Size; Polychlorinated Biphenyls; Rome | 2007 |
Individual differences in response to novelty predict prefrontal cortex dopamine transporter function and cell surface expression.
Topics: Aconitine; Animals; Behavior, Animal; Binding, Competitive; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Exploratory Behavior; Male; Motor Activity; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phenotype; Prefrontal Cortex; Presynaptic Terminals; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Synaptosomes; Tobacco Use Disorder | 2007 |
Gestational exposure to nicotine and monoamine oxidase inhibitors influences cocaine-induced locomotion in adolescent rats.
Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Clorgyline; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Factor Analysis, Statistical; Female; Infusion Pumps, Implantable; Injections, Intraperitoneal; Monoamine Oxidase Inhibitors; Motor Activity; Nicotine; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Selegiline; Sensory Thresholds; Time Factors; Vasoconstrictor Agents | 2007 |
First-principles calculation of pKa for cocaine, nicotine, neurotransmitters, and anilines in aqueous solution.
Topics: Aniline Compounds; Cocaine; Kinetics; Neurotransmitter Agents; Nicotine; Solutions; Static Electricity; Thermodynamics; Water | 2007 |
Nicotine as a conditioned stimulus: impact of attention-deficit/hyperactivity disorder medications.
Topics: Animals; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Bupropion; Cocaine; Conditioning, Operant; Conditioning, Psychological; Discrimination Learning; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Generalization, Psychological; Male; Methylphenidate; Nicotine; Nicotinic Antagonists; Piperazines; Propylamines; Rats; Rats, Sprague-Dawley | 2007 |
Topiramate does not alter nicotine or cocaine discrimination in rats.
Topics: Animals; Anticonvulsants; Cocaine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fructose; Injections, Intraperitoneal; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Topiramate | 2008 |
Cotinine selectively activates a subpopulation of alpha3/alpha6beta2 nicotinic receptors in monkey striatum.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Azetidines; Brain; Cocaine; Conotoxins; Cotinine; Dopamine; Dopamine Agents; Female; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Saimiri | 2008 |
Effects of nicotine, methamphetamine and cocaine on extracellular levels of acetylcholine in the interpeduncular nucleus of rats.
Topics: Acetylcholine; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrochemistry; Extracellular Fluid; Female; Methamphetamine; Microdialysis; Nicotine; Nicotinic Agonists; Pedunculopontine Tegmental Nucleus; Rats; Rats, Sprague-Dawley | 2008 |
Prenatal nicotine exposure changes natural and drug-induced reinforcement in adolescent male rats.
Topics: Aging; Animals; Brain; Brain Chemistry; Causality; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Male; Nicotine; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; RNA, Messenger; Self Administration; Smoking; Stereotyped Behavior; Tobacco Use Disorder | 2008 |
Nails of newborns in monitoring drug exposure during pregnancy.
Topics: Caffeine; Central Nervous System Stimulants; Cocaine; Cotinine; Dopamine Uptake Inhibitors; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Maternal-Fetal Exchange; Methadone; Morphine; Nails; Narcotics; Nicotine; Nicotinic Agonists; Pregnancy; Smoking | 2008 |
Effects of chronic caffeine exposure on adenosinergic modulation of the discriminative-stimulus effects of nicotine, methamphetamine, and cocaine in rats.
Topics: Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Cocaine; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Methamphetamine; Nicotine; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Time Factors | 2009 |
Cocaine from drains in Spain.
Topics: Caffeine; Cocaine; Nicotine; Rivers; Seasons; Spain; Water Pollutants, Chemical; Water Purification; Water Supply | 2008 |
Prenatal nicotine and/or cocaine differentially alters nicotine-induced sensitization in aging offspring.
Topics: Adolescent; Adult; Aging; Animals; Behavior, Animal; Child; Cocaine; Dopamine Uptake Inhibitors; Female; Habituation, Psychophysiologic; Humans; Male; Motor Activity; Nicotine; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 2008 |
Pavlovian drug discrimination with bupropion as a feature positive occasion setter: substitution by methamphetamine and nicotine, but not cocaine.
Topics: Bupropion; Cocaine; Conditioning, Classical; Discrimination Learning; Dopamine Uptake Inhibitors; Humans; Methamphetamine; Nicotine; Peritoneum | 2009 |
Ambient air quality and drug aftermaths of the Notte Bianca (White Night) holidays in Rome.
Topics: Air Pollutants; Air Pollution; Alkanes; Caffeine; Cocaine; Cotinine; Environmental Monitoring; Holidays; Nicotine; Nitro Compounds; Nitrogen Dioxide; Ozone; Particulate Matter; Polycyclic Aromatic Hydrocarbons; Rome; Temperature; Threshold Limit Values; Wind | 2009 |
Simultaneous quantification of nicotine, opioids, cocaine, and metabolites in human fetal postmortem brain by liquid chromatography tandem mass spectrometry.
Topics: Analgesics, Opioid; Brain; Chromatography, Liquid; Cocaine; Humans; Nicotine; Sensitivity and Specificity; Tandem Mass Spectrometry | 2009 |
Nicotine is neuroprotective when administered before but not after nigrostriatal damage in rats and monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Analysis of Variance; Animals; Autoradiography; Cocaine; Conotoxins; Corpus Striatum; Cotinine; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Iodine Isotopes; Male; Motor Activity; Neuroprotective Agents; Neurotoxicity Syndromes; Nicotine; Oxidopamine; Protein Binding; Rats; Rats, Sprague-Dawley; Saimiri; Substantia Nigra; Time Factors | 2009 |
Differences between nicotine and cocaine-induced conditioned place preferences.
Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Benzazepines; Cocaine; Conditioning, Classical; Dopamine Antagonists; Dopamine Uptake Inhibitors; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phentolamine; Space Perception | 2010 |
Self-administration of cocaine and nicotine mixtures by rhesus monkeys.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Combinations; Macaca mulatta; Male; Nicotine; Nicotinic Agonists; Self Administration | 2009 |
Age-dependent effects of low-dose nicotine treatment on cocaine-induced behavioral plasticity in rats.
Topics: Adaptation, Physiological; Aging; Analysis of Variance; Animals; Animals, Newborn; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Exploratory Behavior; Locomotion; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley | 2009 |
Sex differences in the self-administration of cannabinoids and other drugs of abuse.
Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Cannabinoids; Cocaine; Disease Models, Animal; Ethanol; Female; Humans; Illicit Drugs; Male; Nicotine; Self Administration; Sex Characteristics; Substance-Related Disorders | 2009 |
Longitudinal study of maternal report of sleep problems in children with prenatal exposure to cocaine and other drugs.
Topics: Analysis of Variance; Child; Child, Preschool; Cocaine; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Longitudinal Studies; Male; Multivariate Analysis; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Sleep; Sleep Wake Disorders; Substance-Related Disorders; Surveys and Questionnaires | 2009 |
Are we ignoring the clouds on the horizon while looking for sharks? Commentary on "longitudinal study of maternal report of sleep problems in children with prenatal exposure to cocaine and other drugs".
Topics: Child; Child, Preschool; Cocaine; Female; Humans; Infant; Infant, Newborn; Male; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Sleep Wake Disorders | 2009 |
Gas chromatography-mass spectrometry assay for the simultaneous quantification of drugs of abuse in human placenta at 12th week of gestation.
Topics: Abortion, Induced; Amphetamines; Cocaine; Cotinine; Dronabinol; Female; Forensic Toxicology; Ganglionic Stimulants; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Maternal Exposure; Maternal-Fetal Exchange; Methadone; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Nicotine; Placenta; Pregnancy; Pregnancy Trimester, First; Specimen Handling; Substance Abuse Detection | 2010 |
Effect of nicotine and cocaine on neurofilaments and receptors in whole brain tissue and synaptoneurosome preparations.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Brain; Cocaine; Cytoskeleton; Dopamine Uptake Inhibitors; Ganglionic Stimulants; Intermediate Filament Proteins; Male; Mice; Mice, Inbred C57BL; Nicotine; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Synaptosomes | 2010 |
Nicotinic receptor-mediated reduction in L-DOPA-induced dyskinesias may occur via desensitization.
Topics: Amphetamine; Animals; Antiparkinson Agents; Autoradiography; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Calcium Channel Blockers; Central Nervous System Stimulants; Cocaine; Conotoxins; Dopamine Plasma Membrane Transport Proteins; Dyskinesia, Drug-Induced; Functional Laterality; Levodopa; Male; Mecamylamine; Neostriatum; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Stereotyped Behavior | 2010 |
The effects of response operandum and prior food training on intravenous nicotine self-administration in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extinction, Psychological; Food Preferences; Infusions, Intravenous; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration; Sucrose; Sweetening Agents | 2010 |
Sleep problems in children with prenatal substance exposure: the Maternal Lifestyle study.
Topics: Cannabinoids; Chi-Square Distribution; Child; Child, Preschool; Cocaine; Ethanol; Female; Humans; Infant; Infant, Newborn; Longitudinal Studies; Male; Narcotics; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Sleep; Sleep Wake Disorders; Substance-Related Disorders; Surveys and Questionnaires | 2010 |
Nicotine and cocaine self-administration using a multiple schedule of intravenous drug and sucrose reinforcement in rats.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Benzazepines; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Extinction, Psychological; Food Preferences; Infusions, Intravenous; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Sucrose | 2010 |
Effects of fatty acid amide hydrolase inhibition on neuronal responses to nicotine, cocaine and morphine in the nucleus accumbens shell and ventral tegmental area: involvement of PPAR-alpha nuclear receptors.
Topics: Amidohydrolases; Animals; Benzamides; Carbamates; Cocaine; Dopamine; Evoked Potentials; Male; Morphine; Neurons; Nicotine; Nucleus Accumbens; PPAR alpha; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Reward; Ventral Tegmental Area | 2010 |
Conditioned saccharin avoidance and sensitization to drugs of abuse.
Topics: Amphetamine; Animals; Avoidance Learning; Cocaine; Dose-Response Relationship, Drug; Illicit Drugs; Male; Morphine; Nicotine; Rats; Rats, Sprague-Dawley; Saccharin | 2010 |
In silico binary classification QSAR models based on 4D-fingerprints and MOE descriptors for prediction of hERG blockage.
Topics: Carbolines; Cardiotoxins; Chemistry, Pharmaceutical; Cocaine; Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Inhibitory Concentration 50; Molecular Structure; Nicotine; Quantitative Structure-Activity Relationship; Software | 2010 |
The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates conditioned place preference induced by various addictive and non-addictive drugs in rats.
Topics: Animals; Brain; Buspirone; Choice Behavior; Clonidine; Cocaine; Conditioning, Classical; Dose-Response Relationship, Drug; Drug Synergism; Illicit Drugs; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Nicotine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Social Environment; Substance-Related Disorders | 2011 |
Drugs of abuse and stress impair LTP at inhibitory synapses in the ventral tegmental area.
Topics: Analgesics, Opioid; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; gamma-Aminobutyric Acid; Illicit Drugs; Long-Term Potentiation; Morphine; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Stress, Physiological; Synapses; Ventral Tegmental Area | 2010 |
High-throughput simultaneous analysis of buprenorphine, methadone, cocaine, opiates, nicotine, and metabolites in oral fluid by liquid chromatography tandem mass spectrometry.
Topics: Anesthetics, Local; Buprenorphine; Chromatography, Liquid; Cocaine; Female; Ganglionic Stimulants; High-Throughput Screening Assays; Humans; Limit of Detection; Methadone; Narcotics; Nicotine; Pregnancy; Saliva; Tandem Mass Spectrometry | 2010 |
Patterns of responding differentiate intravenous nicotine self-administration from responding for a visual stimulus in C57BL/6J mice.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nicotine; Nicotinic Agonists; Reinforcement Schedule; Self Administration | 2010 |
Probability and predictors of transition from first use to dependence on nicotine, alcohol, cannabis, and cocaine: results of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC).
Topics: Adolescent; Adult; Alcoholism; Cannabis; Cocaine; Cocaine-Related Disorders; Female; Health Surveys; Humans; Male; Marijuana Abuse; Mental Disorders; Middle Aged; Nicotine; Predictive Value of Tests; Probability; Risk Factors; Smoking; Socioeconomic Factors; Tobacco Use Disorder; Young Adult | 2011 |
Mice lacking the galanin gene show decreased sensitivity to nicotine conditioned place preference.
Topics: Animals; Cocaine; Conditioning, Psychological; Galanin; Male; Mice; Mice, 129 Strain; Mice, Congenic; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Morphine; Nicotine; Nucleus Accumbens; Phosphorylation; Reward; Signal Transduction; Synaptic Transmission | 2011 |
Drug-driven AMPA receptor redistribution mimicked by selective dopamine neuron stimulation.
Topics: Animals; Cocaine; Dependovirus; Dopamine; Electrophysiology; Glutamine; Mice; Mice, Inbred C57BL; Morphine; Neurons; Nicotine; Receptors, AMPA; Synapses; Ventral Tegmental Area | 2010 |
Genotype-dependent effects of adolescent nicotine exposure on dopamine functional dynamics in the nucleus accumbens shell in male and female mice: a potential mechanism underlying the gateway effect of nicotine.
Topics: Aging; Animals; Cocaine; Cocaine-Related Disorders; Dopamine; Female; Genotype; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nicotine; Nucleus Accumbens; Reward; Sex Characteristics; Species Specificity | 2011 |
Adolescent nicotine exposure sensitizes cue-induced reinstatement of cocaine seeking in rats bred for high and low saccharin intake.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Extinction, Psychological; Female; Gene-Environment Interaction; Nicotine; Phenotype; Rats; Rats, Sprague-Dawley; Recurrence; Saccharin; Self Administration; Sweetening Agents | 2011 |
Behavior of pharmaceuticals and drugs of abuse in a drinking water treatment plant (DWTP) using combined conventional and ultrafiltration and reverse osmosis (UF/RO) treatments.
Topics: Acetaminophen; Caffeine; Cocaine; Cotinine; Environmental Monitoring; Erythromycin; Halogenation; Illicit Drugs; Iohexol; Kinetics; Nicotine; Osmosis; Ozone; Pharmaceutical Preparations; Ultrafiltration; Water Pollutants, Chemical; Water Pollution, Chemical; Water Purification; Water Supply | 2011 |
Discriminative and reinforcing stimulus effects of nicotine, cocaine, and cocaine + nicotine combinations in rhesus monkeys.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Discrimination, Psychological; Dose-Response Relationship, Drug; Macaca mulatta; Male; Models, Animal; Nicotine; Reinforcement Schedule; Self Administration; Tobacco Use Disorder | 2011 |
Evaluation of the presence of drugs of abuse in tap waters.
Topics: Caffeine; Chromatography, High Pressure Liquid; Cocaine; Cotinine; Drinking Water; Environmental Monitoring; Illicit Drugs; Methadone; Nicotine; Pyrrolidines; Spectrometry, Mass, Electrospray Ionization | 2011 |
Threshold of adulthood for the onset of nicotine self-administration in male and female rats.
Topics: Age Factors; Animals; Cocaine; Conditioning, Operant; Critical Period, Psychological; Estrus; Female; Male; Nicotine; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration; Sex Characteristics | 2011 |
Effects of varenicline on the reinforcing and discriminative stimulus effects of cocaine in rhesus monkeys.
Topics: Animals; Benzazepines; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Discrimination Learning; Discrimination, Psychological; Dopamine Uptake Inhibitors; Macaca mulatta; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Quinoxalines; Reinforcement, Psychology; Self Administration; Time Factors; Varenicline | 2011 |
Executive function profile in the offspring of women that smoked during pregnancy.
Topics: Adolescent; Alcohols; Attention Deficit Disorder with Hyperactivity; Brain Injuries; Brief Psychiatric Rating Scale; Child; Child, Preschool; Cocaine; Demography; Executive Function; Female; Fetal Alcohol Spectrum Disorders; Humans; Internet; Nicotine; Odds Ratio; Pregnancy; Prenatal Exposure Delayed Effects; Prevalence; Smoking; Surveys and Questionnaires | 2012 |
Epigenetics of nicotine: another nail in the coughing.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Epigenesis, Genetic; Histone Deacetylases; Mice; Nicotine | 2011 |
Molecular mechanism for a gateway drug: epigenetic changes initiated by nicotine prime gene expression by cocaine.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Mice; Mice, Inbred C57BL; Nicotine; Theophylline | 2011 |
Involvement of metabotropic glutamate receptor 5 in brain reward deficits associated with cocaine and nicotine withdrawal and somatic signs of nicotine withdrawal.
Topics: Anhedonia; Animals; Brain; Cocaine; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reward; Self Stimulation; Substance Withdrawal Syndrome; Time Factors | 2012 |
Inhibitory inputs from rostromedial tegmental neurons regulate spontaneous activity of midbrain dopamine cells and their responses to drugs of abuse.
Topics: Action Potentials; Analysis of Variance; Animals; Benzoxazines; Cannabinoids; Cocaine; Dopaminergic Neurons; Electric Stimulation; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Morphine; Morpholines; Naloxone; Naphthalenes; Narcotic Antagonists; Narcotics; Neural Inhibition; Neural Pathways; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Physical Stimulation; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Tegmentum Mesencephali; Time Factors; Ventral Tegmental Area | 2012 |
Differential behavioral profiling of stimulant substances in the rat using the LABORAS™ system.
Topics: Animals; Automation; Behavior, Animal; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Dextroamphetamine; Dizocilpine Maleate; Drinking Behavior; Drug Evaluation, Preclinical; Feeding Behavior; Grooming; Ketamine; Male; Modafinil; Motor Activity; Nicotine; Psychotropic Drugs; Rats; Rats, Wistar | 2012 |
Pharmacologic characterization of a nicotine-discriminative stimulus in rhesus monkeys.
Topics: Alkaloids; Animals; Azocines; Benzazepines; Cocaine; Conditioning, Operant; Discrimination Learning; Dopamine Uptake Inhibitors; Drug Interactions; Female; Hypnotics and Sedatives; Macaca mulatta; Male; Mecamylamine; Midazolam; Nicotine; Nicotinic Agonists; Quinolizines; Quinoxalines; Receptors, Nicotinic; Varenicline | 2012 |
Planarians in pharmacology: parthenolide is a specific behavioral antagonist of cocaine in the planarian Girardia tigrina.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cocaine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Agonists; Methamphetamine; N-Methylaspartate; Nicotine; Nicotinic Agonists; Planarians; Regeneration; Seizures; Sesquiterpenes | 2012 |
In vivo comparison of harmine efficacy against psychostimulants: preferential inhibition of the cocaine response through a glutamatergic mechanism.
Topics: Amphetamines; Animals; Cocaine; Excitatory Amino Acid Antagonists; Glutamic Acid; Harmine; Inhibition, Psychological; Kainic Acid; Nicotine; Nicotinic Antagonists; Planarians; Psychotropic Drugs | 2012 |
Airborne psychotropic substances in eight Italian big cities: burdens and behaviours.
Topics: Air Pollutants; Air Pollution; Caffeine; Cities; Cocaine; Environmental Monitoring; Italy; Models, Chemical; Nicotine; Particulate Matter; Psychotropic Drugs; Seasons | 2012 |
Effects of nicotinic acetylcholine receptor agonists on cognition in rhesus monkeys with a chronic cocaine self-administration history.
Topics: Animals; Behavior, Animal; Benzamides; Benzazepines; Bridged Bicyclo Compounds; Cocaine; Cocaine-Related Disorders; Cognition Disorders; Dopamine Uptake Inhibitors; Hippocampus; Learning; Ligands; Macaca mulatta; Male; Memory, Short-Term; Nerve Tissue Proteins; Neurons; Nicotine; Nicotinic Agonists; Nootropic Agents; Quinoxalines; Receptors, Nicotinic; Reversal Learning; Self Administration; Varenicline | 2013 |
Effects of adolescent nicotine exposure and withdrawal on intravenous cocaine self-administration during adulthood in male C57BL/6J mice.
Topics: Adolescent; Adolescent Behavior; Age of Onset; Analysis of Variance; Animals; Body Weight; Catheterization; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cotinine; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Humans; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Nicotine; Random Allocation; Rats; Self Administration; Tobacco Use Disorder | 2014 |
Determination of stimulants using gas chromatography/high-resolution time-of-flight mass spectrometry and a soft ionization source.
Topics: Caffeine; Central Nervous System Stimulants; Cocaine; Codeine; Dopamine Uptake Inhibitors; Equipment Design; GABA Antagonists; Ganglionic Stimulants; Gas Chromatography-Mass Spectrometry; Ions; Methadone; Narcotics; Nicotine; Nikethamide; Norbornanes; Pentylenetetrazole; Phenmetrazine; Sensitivity and Specificity | 2012 |
Disrupted adenovirus-based vaccines against small addictive molecules circumvent anti-adenovirus immunity.
Topics: Adenoviridae; Animals; Antibodies, Neutralizing; Blotting, Western; Caproates; Capsid Proteins; Cocaine; Female; Genetic Vectors; Humans; Mice; Mice, Inbred BALB C; Multiprotein Complexes; Nicotine; Vaccines | 2013 |
Stress produces aversion and potentiates cocaine reward by releasing endogenous dynorphins in the ventral striatum to locally stimulate serotonin reuptake.
Topics: Animals; Avoidance Learning; Brain; Cocaine; Corpus Striatum; Dopamine; Dynorphins; G-Protein-Coupled Receptor Kinase 3; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microinjections; Naltrexone; Narcotic Antagonists; Nicotine; Nucleus Accumbens; p38 Mitogen-Activated Protein Kinases; Raphe Nuclei; Receptors, Opioid, kappa; Reward; Serotonin; Serotonin Plasma Membrane Transport Proteins; Signal Transduction; Stress, Psychological; Substance Withdrawal Syndrome; Synaptosomes | 2012 |
Nicotine reward and affective nicotine withdrawal signs are attenuated in calcium/calmodulin-dependent protein kinase IV knockout mice.
Topics: Animals; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Cocaine; Female; Haplotypes; Humans; Linkage Disequilibrium; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Nucleus Accumbens; Phenotype; Reward; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2012 |
Discriminative stimulus effects of the GABAB receptor-positive modulator rac-BHFF: comparison with GABAB receptor agonists and drugs of abuse.
Topics: Animals; Baclofen; Benzodiazepines; Benzofurans; Cocaine; Columbidae; Diazepam; Discrimination, Psychological; Ethanol; GABA-B Receptor Agonists; Illicit Drugs; Nicotine; Organophosphorus Compounds; Phenols; Sodium Oxybate | 2013 |
Enhanced nicotine-seeking behavior following pre-exposure to repeated cocaine is accompanied by changes in BDNF in the nucleus accumbens of rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; Dynorphins; Gene Expression; Male; Motor Activity; Neuropeptide Y; Nicotine; Nucleus Accumbens; Rats; Rats, Wistar; Receptor, trkB; Receptors, Corticotropin-Releasing Hormone; Receptors, Opioid, mu; Risk Factors; Self Administration; Tobacco Use Disorder | 2013 |
Effects of chronic buspirone treatment on nicotine and concurrent nicotine+cocaine self-administration.
Topics: Animals; Anti-Anxiety Agents; Buspirone; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Macaca mulatta; Nicotine; Nicotinic Agonists; Reinforcement Schedule; Self Administration | 2013 |
Nicotine primes the effect of cocaine on the induction of LTP in the amygdala.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amygdala; Animals; Bridged-Ring Compounds; Cocaine; Dihydro-beta-Erythroidine; Dopamine Uptake Inhibitors; Drug Synergism; Histone Deacetylase Inhibitors; Hydroxamic Acids; Long-Term Potentiation; Male; Mice; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Spiro Compounds; Time Factors; Vorinostat | 2013 |
The cannabinoid CB2 receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice.
Topics: Animals; Anisoles; Behavior, Animal; Cocaine; Conditioning, Psychological; Cyclohexanols; Dose-Response Relationship, Drug; Female; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Receptor, Cannabinoid, CB2; Reward; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2013 |
Planarians require an intact brain to behaviorally react to cocaine, but not to react to nicotine.
Topics: Animals; Brain; Cocaine; Dose-Response Relationship, Drug; Nicotine; Planarians; Regeneration | 2013 |
Prenatal substance exposure: neurobiologic organization at 1 month.
Topics: Alcoholic Beverages; Analgesics, Opioid; Attention; Autonomic Nervous System; Cannabis; Cocaine; Cohort Studies; Female; Humans; Infant; Infant Behavior; Intensive Care, Neonatal; Life Style; Male; Maternal Exposure; Nicotine; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Smoking; Substance-Related Disorders | 2013 |
Interview with Frank Ivy Carroll.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Dopamine Uptake Inhibitors; Humans; Nicotine; Protein Binding; Pyridines; Receptor, Adenosine A2B; Receptors, Nicotinic; Research; Substance-Related Disorders; Tropanes | 2013 |
A systematic assessment of delay discounting in relation to cocaine and nicotine dependence.
Topics: Adult; Age of Onset; Algorithms; Choice Behavior; Cocaine; Cocaine-Related Disorders; Data Interpretation, Statistical; Diagnostic and Statistical Manual of Mental Disorders; Educational Status; Female; Humans; Impulsive Behavior; Income; Male; Nicotine; Nicotinic Agonists; Tobacco Use Disorder; Young Adult | 2013 |
Choline transporter hemizygosity results in diminished basal extracellular dopamine levels in nucleus accumbens and blunts dopamine elevations following cocaine or nicotine.
Topics: Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Gene Expression Regulation; Hemizygote; Membrane Transport Proteins; Mice; Nicotine; Nicotinic Agonists; Nucleus Accumbens | 2013 |
Age-dependent alterations in reward-seeking behavior after brief nicotine exposure.
Topics: Aging; Animals; Appetitive Behavior; Catheters, Indwelling; Cocaine; Conditioning, Operant; Dietary Sucrose; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Male; Nicotine; Nicotinic Agonists; Rats, Sprague-Dawley; Reward; Self Administration | 2014 |
Analysis of cocaine and nicotine metabolites in wastewater by liquid chromatography-tandem mass spectrometry. Cross abuse index patterns on a major community.
Topics: Chromatography, Liquid; Cocaine; Environmental Monitoring; Humans; Illicit Drugs; Nicotine; Solid Phase Extraction; Substance-Related Disorders; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical; Water Pollution, Chemical | 2014 |
Effects of chronic varenicline treatment on nicotine, cocaine, and concurrent nicotine+cocaine self-administration.
Topics: Animals; Benzazepines; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Feeding Behavior; Female; Macaca mulatta; Male; Motivation; Nicotine; Nicotinic Agonists; Quinoxalines; Reinforcement, Psychology; Self Administration; Tobacco Use Disorder; Varenicline | 2014 |
Viral over-expression of D1 dopamine receptors in the prefrontal cortex increase high-risk behaviors in adults: comparison with adolescents.
Topics: Animals; Central Nervous System Depressants; Cocaine; Conditioning, Psychological; Delay Discounting; Dietary Sucrose; Dopamine Uptake Inhibitors; Ethanol; Feeding Behavior; Genetic Vectors; Lentivirus; Male; Motivation; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Prefrontal Cortex; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Risk-Taking; Space Perception | 2014 |
Time-dependent changes in nicotine behavioral responsivity during early withdrawal from chronic cocaine administration and attenuation of cocaine sensitization by mecamylamine.
Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Male; Mecamylamine; Motor Activity; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2014 |
Effects of psychotropic drugs on second messenger signaling and preference for nicotine in juvenile male mice.
Topics: Animals; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Fluoxetine; Gene Expression; Male; MAP Kinase Signaling System; Methylphenidate; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Psychotropic Drugs; RNA, Messenger; Second Messenger Systems; Space Perception; Time Factors; Ventral Tegmental Area | 2014 |
Mechanisms of metabonomic for a gateway drug: nicotine priming enhances behavioral response to cocaine with modification in energy metabolism and neurotransmitter level.
Topics: Amino Acids; Animals; Behavior, Animal; Choice Behavior; Cocaine; Conditioning, Psychological; Energy Metabolism; Least-Squares Analysis; Male; Membranes; Metabolic Networks and Pathways; Metabolome; Metabolomics; Mice, Inbred C57BL; Neostriatum; Neurotransmitter Agents; Nicotine; Nucleus Accumbens; Proton Magnetic Resonance Spectroscopy | 2014 |
Risk of neurobehavioral disinhibition in prenatal methamphetamine-exposed young children with positive hair toxicology results.
Topics: Amphetamine-Related Disorders; Case-Control Studies; Child; Child Development; Cocaine; Female; Hair; Humans; Methamphetamine; Mothers; Nicotiana; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Risk | 2014 |
D1/D5 receptors and histone deacetylation mediate the Gateway Effect of LTP in hippocampal dentate gyrus.
Topics: Animals; Cocaine; Dentate Gyrus; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Nicotine; Receptors, Dopamine D1; Receptors, Dopamine D5; Vorinostat | 2014 |
The involvement of accumbal glycine receptors in the dopamine-elevating effects of addictive drugs.
Topics: Animals; Central Nervous System Depressants; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dronabinol; Ethanol; Glycine Agents; Hallucinogens; Illicit Drugs; Male; Microdialysis; Microelectrodes; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats, Wistar; Receptors, Glycine; Strychnine; Synaptic Transmission | 2014 |
Self-administration of ethanol, cocaine, or nicotine does not decrease the soma size of ventral tegmental area dopamine neurons.
Topics: Animals; Cell Size; Cocaine; Dopaminergic Neurons; Ethanol; Male; Mice, Inbred C57BL; Nicotine; Rats, Wistar; Self Administration; Ventral Tegmental Area | 2014 |
Inhibitory actions of mGlu4 receptor ligands on cocaine-, but not nicotine-, induced sensitizing and conditioning locomotor responses in rats.
Topics: Aminobutyrates; Animals; Cocaine; Conditioning, Psychological; Ligands; Male; Motor Activity; Nicotine; Phosphinic Acids; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 2014 |
Pavlovian discriminative stimulus effects of methamphetamine in male Japanese quail (Coturnix japonica).
Topics: Animals; Benzazepines; Central Nervous System Stimulants; Cocaine; Conditioning, Classical; Coturnix; Discrimination, Psychological; Female; Generalization, Psychological; Haloperidol; Male; Methamphetamine; Nicotine; Receptors, Dopamine D1; Sexual Behavior, Animal | 2014 |
Nicotine enhances the expression of a sucrose or cocaine conditioned place preference in adult male rats.
Topics: Animals; Cocaine; Conditioning, Classical; Male; Nicotine; Rats; Rats, Sprague-Dawley; Sucrose | 2014 |
Differential roles of α6β2* and α4β2* neuronal nicotinic receptors in nicotine- and cocaine-conditioned reward in mice.
Topics: Animals; Avoidance Learning; Cocaine; Conditioning, Psychological; Conotoxins; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Food; Lithium Chloride; Male; Mice, Inbred C57BL; Mice, Knockout; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Reward; Spatial Behavior | 2015 |
Shattuck Lecture. A molecular basis for nicotine as a gateway drug.
Topics: Animals; Brain; Cocaine; Humans; Learning; Memory, Long-Term; Mice; Nicotine; Substance-Related Disorders | 2014 |
A molecular basis for nicotine as a gateway drug.
Topics: Animals; Brain; Cocaine; Humans; Memory, Long-Term; Nicotine; Substance-Related Disorders | 2014 |
A molecular basis for nicotine as a gateway drug.
Topics: Animals; Brain; Cocaine; Humans; Memory, Long-Term; Nicotine; Substance-Related Disorders | 2014 |
Individual differences in the reinforcing and punishing effects of nicotine in rhesus monkeys.
Topics: Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Individuality; Macaca mulatta; Male; Nicotine; Punishment; Reinforcement, Psychology; Self Administration | 2015 |
Evidence for a role for α6(∗) nAChRs in l-dopa-induced dyskinesias using Parkinsonian α6(∗) nAChR gain-of-function mice.
Topics: Adrenergic Agents; Analysis of Variance; Animals; Antiparkinson Agents; Benserazide; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Levodopa; Male; Mice; Mice, Transgenic; Nicotine; Nicotinic Agonists; Oxidopamine; Parkinsonian Disorders; Protein Binding; Receptors, Nicotinic | 2015 |
Effects of continuous nicotine treatment and subsequent termination on cocaine versus food choice in male rhesus monkeys.
Topics: Animals; Choice Behavior; Cocaine; Dose-Response Relationship, Drug; Food; Macaca mulatta; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Self Administration | 2015 |
Differential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on nicotine versus cocaine self-administration and relapse in squirrel monkeys.
Topics: Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Cocaine-Related Disorders; Cues; Dose-Response Relationship, Drug; Drug Interactions; Drug-Seeking Behavior; Male; Nicotine; Receptors, Metabotropic Glutamate; Recurrence; Reinforcement, Psychology; Saimiri; Self Administration; Tobacco Use Disorder | 2016 |
Adolescent nicotine exposure fails to impact cocaine reward, aversion and self-administration in adult male rats.
Topics: Age Factors; Animals; Avoidance Learning; Cocaine; Dose-Response Relationship, Drug; Male; Nicotine; Rats; Rats, Sprague-Dawley; Reward; Self Administration | 2015 |
Dopaminergic mediation of the discriminative stimulus functions of modafinil in rats.
Topics: Amphetamine; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Dextroamphetamine; Dopamine; Dopamine Agents; Generalization, Psychological; Male; Methylphenidate; Modafinil; Nicotine; Piperazines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Wakefulness-Promoting Agents | 2015 |
Nucleosome Repositioning: A Novel Mechanism for Nicotine- and Cocaine-Induced Epigenetic Changes.
Topics: Base Sequence; Cell Line, Tumor; Cocaine; Early Growth Response Protein 1; Epigenesis, Genetic; Gene Expression Regulation; Gene Ontology; Humans; Nicotine; Nucleosomes; Promoter Regions, Genetic | 2015 |
Sex differences in the acquisition and maintenance of cocaine and nicotine self-administration in rats.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Female; Male; Nicotine; Rats; Self Administration; Sex Characteristics; Substance-Related Disorders | 2016 |
Self-administration of the anandamide transport inhibitor AM404 by squirrel monkeys.
Topics: Animals; Arachidonic Acids; Benzamides; Cannabinoid Receptor Antagonists; Carbamates; Cocaine; Dose-Response Relationship, Drug; Dronabinol; Drug-Seeking Behavior; Endocannabinoids; Male; Nicotine; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Reinforcement, Psychology; Reward; Rimonabant; Saimiri; Self Administration | 2016 |
Early adolescent nicotine exposure affects later-life cocaine reward in mice.
Topics: Aging; Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Eating; Male; Mice; Mice, Inbred ICR; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Reward | 2016 |
Influence of experimental history on nicotine self-administration in squirrel monkeys.
Topics: Alkaloids; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Eating; Male; Nicotine; Pyridines; Reinforcement, Psychology; Saimiri; Self Administration | 2016 |
Reinforcing effectiveness of nicotine in nonhuman primates: effects of nicotine dose and history of nicotine self-administration.
Topics: Administration, Intravenous; Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Feeding Behavior; Macaca mulatta; Male; Nicotine; Reinforcement Schedule; Reinforcement, Psychology; Self Administration | 2016 |
Differential behavioral and molecular alterations upon protracted abstinence from cocaine versus morphine, nicotine, THC and alcohol.
Topics: Alcohol Abstinence; Amygdala; Analgesics, Opioid; Animals; Anxiety; Behavior, Animal; Brain; Cannabinoid Receptor Agonists; Central Nervous System Depressants; Cocaine; Dopamine Uptake Inhibitors; Dronabinol; Drug-Seeking Behavior; Emotions; Ethanol; Male; Mice; Morphine; Motivation; Nicotine; Nicotinic Agonists; Proto-Oncogene Proteins c-fos; Social Behavior; Stereotyped Behavior; Substance Withdrawal Syndrome | 2017 |
Nicotine produces long-term increases in cocaine reinforcement in adolescent but not adult rats.
Topics: Aging; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Synergism; Male; Motor Activity; Nicotine; Nicotinic Agonists; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Sexual Maturation; Time Factors; Tobacco Use Disorder | 2017 |
Toward early estimation and treatment of addiction vulnerability: radial arm maze and N-acetyl cysteine before cocaine sensitization or nicotine self-administration in neonatal ventral hippocampal lesion rats.
Topics: Acetylcysteine; Animals; Animals, Newborn; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Drug-Seeking Behavior; Free Radical Scavengers; Hippocampus; Male; Memory Disorders; Memory, Short-Term; Nicotine; Nicotinic Agonists; Prefrontal Cortex; Rats; Rats, Sprague-Dawley | 2016 |
Comparison of pharmaceutical, illicit drug, alcohol, nicotine and caffeine levels in wastewater with sale, seizure and consumption data for 8 European cities.
Topics: Alcohol Drinking; Amphetamines; Beverages; Caffeine; Central Nervous System Stimulants; Cities; Cocaine; Commerce; Ethanol; Europe; Humans; Illicit Drugs; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Nicotiana; Nicotine; Pharmaceutical Preparations; Substance Abuse Detection; Substance-Related Disorders; Tobacco Use; Wastewater; Water Pollutants, Chemical | 2016 |
The anatomical mummies of Mombello: detection of cocaine, nicotine, and caffeine in the hair of psychiatric patients of the early 20th century.
Topics: Caffeine; Chromatography, High Pressure Liquid; Cocaine; Female; Hair; History, 20th Century; Hospitals, Psychiatric; Humans; Italy; Male; Mass Spectrometry; Mummies; Nicotine | 2017 |
The contribution of α4β2 and non-α4β2 nicotinic acetylcholine receptors to the discriminative stimulus effects of nicotine and varenicline in mice.
Topics: Aconitine; Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Animals; Azocines; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Dihydro-beta-Erythroidine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Hypnotics and Sedatives; Ibogaine; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Midazolam; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Quinolizines; Receptors, Nicotinic; Varenicline | 2017 |
Attenuating Nicotine Reinforcement and Relapse by Enhancing Endogenous Brain Levels of Kynurenic Acid in Rats and Squirrel Monkeys.
Topics: Animals; Cocaine; Dopamine; Isoxazoles; Kynurenic Acid; Male; Nicotine; Nucleus Accumbens; Phenylurea Compounds; Rats; Recurrence; Reinforcement, Psychology; Saimiri; Secondary Prevention; Self Administration; Sulfonamides; Thiazoles | 2017 |
In vivo interactions between α7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α: Implication for nicotine dependence.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Anesthetics, Local; Animals; Benzamides; Bridged Bicyclo Compounds; Cocaine; Conditioning, Operant; Disease Models, Animal; Fenofibrate; Hypolipidemic Agents; Male; Mice; Mice, Inbred ICR; Nicotine; Nicotinic Agonists; Oxazoles; PPAR alpha; Pyrimidines; Self Administration; Substance Withdrawal Syndrome; Tobacco Use Disorder; Tyrosine | 2017 |
Nicotine- and cocaine-triggered methamphetamine reinstatement in female and male Sprague-Dawley rats.
Topics: Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Drug-Seeking Behavior; Extinction, Psychological; Female; Male; Methamphetamine; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2017 |
Nicotine pretreatment reduced cocaine-induced CPP and its reinstatement in a sex- and dose-related manner in adult C57BL/6J mice.
Topics: Aging; Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psychological; Female; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Sex Characteristics | 2017 |
The effect of nicotine pre-exposure on demand for cocaine and sucrose in male rats.
Topics: Animals; Cocaine; Conditioning, Operant; Male; Nicotine; Rats; Rats, Long-Evans; Reinforcement, Psychology; Self Administration; Sucrose | 2018 |
Ethical Implications in Vaccine Pharmacotherapy for Treatment and Prevention of Drug of Abuse Dependence.
Topics: Analgesics, Opioid; Antibodies; Brain; Cocaine; Ethics, Clinical; Female; Humans; Immunotherapy; Methamphetamine; Morals; Nicotine; Pregnancy; Pregnancy Complications; Substance-Related Disorders; Vaccination; Vaccines | 2018 |
Cocaine + nicotine mixture enhances induction and expression of behavioral sensitization in rats.
Topics: Animals; Behavior, Animal; Central Nervous System Sensitization; Cocaine; Dopamine Uptake Inhibitors; Drug Synergism; Locomotion; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar | 2018 |
Effects of drugs of abuse on channelrhodopsin-2 function.
Topics: Cations; Channelrhodopsins; Cocaine; Dose-Response Relationship, Drug; Dronabinol; Ethanol; Gadolinium; HEK293 Cells; Humans; Illicit Drugs; Magnesium; Membrane Potentials; Membrane Transport Modulators; Methamphetamine; Morphine; Nicotine; Patch-Clamp Techniques; Tetrodotoxin; Toluene; Transfection | 2018 |
c-Fos marking of identified midbrain neurons coactive after nicotine administration in-vivo.
Topics: Animals; Autonomic Nervous System; Cocaine; Dopamine Uptake Inhibitors; Dopaminergic Neurons; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Neurons; Nicotine; Nicotinic Agonists; Proto-Oncogene Proteins c-fos; Reward; Substance Withdrawal Syndrome; Transcriptional Activation; Ventral Tegmental Area | 2018 |
Differential cross-tolerance to the effects of nicotinic acetylcholine receptor drugs in C57BL/6J mice following chronic varenicline.
Topics: Alkaloids; Animals; Azocines; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Conditioning, Operant; Drug Tolerance; Female; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Quinolizines; Receptors, Nicotinic; Reinforcement, Psychology; Smoking Cessation; Varenicline | 2019 |
ANCO-GeneDB: annotations and comprehensive analysis of candidate genes for alcohol, nicotine, cocaine and opioid dependence.
Topics: Alcoholism; Cocaine; Databases, Genetic; Genetic Predisposition to Disease; Genetic Variation; Humans; Internet; Molecular Sequence Annotation; Nicotine; Opioid-Related Disorders; Polymorphism, Single Nucleotide; User-Computer Interface | 2018 |
Behavioral effects of psychostimulants in mutant mice with cell-type specific deletion of CB2 cannabinoid receptors in dopamine neurons.
Topics: Amphetamine; Animals; Cannabinoids; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Eukaryotic Initiation Factor-3; Gene Expression Regulation; Hyperkinesis; Locomotion; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nicotine; Receptor, Cannabinoid, CB2; RNA, Messenger; Statistics, Nonparametric; Time Factors; Tyrosine 3-Monooxygenase | 2019 |
Cocaine, nicotine, and their conditioned contexts enhance consolidation of object memory in rats.
Topics: Animals; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Memory Consolidation; Nicotine; Nicotinic Agonists; Nootropic Agents; Rats, Sprague-Dawley; Recognition, Psychology; Substance-Related Disorders | 2019 |
Adolescence versus adulthood: Differences in basal mesolimbic and nigrostriatal dopamine transmission and response to drugs of abuse.
Topics: Age Factors; Analgesics, Opioid; Animals; Brain; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dronabinol; Ganglionic Stimulants; Male; Microdialysis; Morphine; Nicotine; Nucleus Accumbens; Psychotropic Drugs; Rats; Substance-Related Disorders; Synaptic Transmission | 2020 |
Sensitization-dependent nicotine place preference in the adult zebrafish.
Topics: Animals; Brain; Central Nervous System Sensitization; Cocaine; Conditioning, Classical; Homeodomain Proteins; Locomotion; Nicotine; Receptors, Nicotinic; Tyrosine 3-Monooxygenase; Zebrafish; Zebrafish Proteins | 2019 |
The continuing search for an addiction vaccine.
Topics: Cocaine; Heroin; Humans; Methamphetamine; Nicotine; Substance-Related Disorders; Vaccines | 2019 |
Natural and Drug Rewards Engage Distinct Pathways that Converge on Coordinated Hypothalamic and Reward Circuits.
Topics: Agouti-Related Protein; Amphetamine; Animals; Central Nervous System Depressants; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Ethanol; Feeding Behavior; Hypothalamus; Mice; Neural Pathways; Neurons; Nicotine; Nicotinic Agonists; Pro-Opiomelanocortin; Reward; Vagotomy; Vagus Nerve | 2019 |
Delta-9-THC exposure during zebra finch sensorimotor vocal learning increases cocaine reinforcement in adulthood.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Classical; Dose-Response Relationship, Drug; Dronabinol; Female; Finches; Learning; Male; Nicotine; Reinforcement, Psychology; Reward; Sensorimotor Cortex; Sex Factors; Vocalization, Animal | 2019 |
Prenatal nicotine sex-dependently alters adolescent dopamine system development.
Topics: Animals; Animals, Newborn; Catechol O-Methyltransferase; Cocaine; Corpus Striatum; Dopamine; Female; Locomotion; Male; Nicotine; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Sex Factors; Vasoconstrictor Agents | 2019 |
Subcortical surface morphometry in substance dependence: An ENIGMA addiction working group study.
Topics: Adolescent; Adult; Brain; Cannabis; Cocaine; Ethanol; Female; Humans; Magnetic Resonance Imaging; Male; Methamphetamine; Neuroimaging; Nicotine; Substance-Related Disorders; Young Adult | 2020 |
Effects of chronic treatment with bupropion on self-administration of nicotine + cocaine mixtures in nonhuman primates.
Topics: Animals; Bupropion; Central Nervous System Stimulants; Cocaine; Dose-Response Relationship, Drug; Macaca mulatta; Male; Nicotine; Reinforcement, Psychology; Self Administration; Smoking Cessation Agents | 2020 |
Nicotine, cocaine, amphetamine, morphine, and ethanol increase norepinephrine output in the bed nucleus of stria terminalis of freely moving rats.
Topics: Amphetamine; Animals; Cocaine; Drug-Seeking Behavior; Ethanol; Male; Morphine; Nicotine; Norepinephrine; Rats; Septal Nuclei | 2021 |
Microglial activation increases cocaine self-administration following adolescent nicotine exposure.
Topics: Aminopyridines; Animals; Chemokine CX3CL1; Cocaine; Disease Models, Animal; Drug-Seeking Behavior; Electronic Nicotine Delivery Systems; Female; Gene Expression Regulation; Male; Microglia; Minocycline; Nicotine; Phenotype; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reinforcement, Psychology; Reward; Self Administration; Synaptophysin | 2020 |
Measuring functional brain recovery in regenerating planarians by assessing the behavioral response to the cholinergic compound cytisine.
Topics: Alkaloids; Anesthetics, Local; Animals; Azocines; Brain; Carbachol; Cholinergic Agents; Cocaine; Cotinine; Dose-Response Relationship, Drug; Ethanol; Nicotine; Planarians; Quinolizines; Regeneration; Seizures | 2020 |
Early adolescent subchronic low-dose nicotine exposure increases subsequent cocaine and fentanyl self-administration in Sprague-Dawley rats.
Topics: Age Factors; Animals; Cocaine; Dose-Response Relationship, Drug; Female; Fentanyl; Male; Nicotine; Rats; Rats, Sprague-Dawley; Self Administration; Sex Factors | 2021 |
Suppressing effect of the novel positive allosteric modulator of the GABA
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dopamine Uptake Inhibitors; GABA Modulators; Hyperkinesis; Locomotion; Male; Mice; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Receptors, GABA-B | 2021 |
Memory enhancing effects of nicotine, cocaine, and their conditioned stimuli; effects of beta-adrenergic and dopamine D2 receptor antagonists.
Topics: Adrenergic Agents; Animals; Cocaine; Dopamine D2 Receptor Antagonists; Male; Nicotine; Rats; Rats, Sprague-Dawley | 2021 |
Influence of Contingent and Noncontingent Drug Histories on the Development of High Levels of MDPV Self-Administration.
Topics: Adrenergic Uptake Inhibitors; Animals; Behavior, Addictive; Benzodioxoles; Cocaine; Fentanyl; Ketamine; Male; Nicotine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration; Synthetic Cathinone | 2021 |
JQ1 attenuates psychostimulant- but not opioid-induced conditioned place preference.
Topics: Amphetamine; Anesthetics, Local; Animals; Azepines; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Epigenomics; Learning; Male; Memory; Mice; Morphine; Nicotine; Triazoles | 2022 |
White matter microstructure differences in individuals with dependence on cocaine, methamphetamine, and nicotine: Findings from the ENIGMA-Addiction working group.
Topics: Cocaine; Diffusion Tensor Imaging; Humans; Methamphetamine; Nicotine; White Matter | 2022 |
Substance use disorders among primary care patients screening positive for unhealthy alcohol use.
Topics: Adult; Alcoholism; Analgesics, Opioid; Cocaine; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Nicotine; Primary Health Care; Substance-Related Disorders | 2022 |
Long-term monitoring of drug consumption patterns during the COVID-19 pandemic in a small-sized community in Brazil through wastewater-based epidemiology.
Topics: Amphetamine; Brazil; Caffeine; Cocaine; COVID-19; Dronabinol; Humans; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Nicotine; Pandemics; Substance Abuse Detection; Substance-Related Disorders; Wastewater; Wastewater-Based Epidemiological Monitoring; Water Pollutants, Chemical | 2022 |
The interaction effects of secondhand smoke exposure and overweight on the prevalence of hypertension in Chinese coke oven workers and NHANES participants (2013-2016).
Topics: Coke; Cross-Sectional Studies; Humans; Hypertension; Nicotine; Nutrition Surveys; Occupational Exposure; Overweight; Polycyclic Aromatic Hydrocarbons; Prevalence; Pyrenes; Tobacco Smoke Pollution | 2022 |
Monitoring of changes in illicit drugs, alcohol, and nicotine consumption during Ramadan via wastewater analysis.
Topics: Amphetamine; Cannabis; Cocaine; Ethanol; Heroin; Humans; Illicit Drugs; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Nicotine; Substance Abuse Detection; Wastewater; Water Pollutants, Chemical | 2022 |
Prenatal and Postnatal Cocaine Enhances the Induction and Expression of Locomotor Sensitization to Nicotine in Male Rats.
Topics: Adult; Animals; Cocaine; Female; Humans; Male; Nicotine; Pregnancy; Rats; Rats, Wistar | 2022 |
Effects of isoflurane anesthesia on addictive behaviors in rats.
Topics: Anesthesia; Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Dopamine; Dose-Response Relationship, Drug; Isoflurane; Nicotine; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration; Sucrose | 2022 |
Associations Between E-cigarettes and Subsequent Cocaine Use in Adolescence: An Analysis of the UK Millennium Cohort Study.
Topics: Adolescent; Child; Cocaine; Cohort Studies; Electronic Nicotine Delivery Systems; Humans; Nicotine; Prospective Studies; Tobacco Products; Vaping | 2023 |
Residues of ractopamine, a livestock feed additive, in meat might alleviate misuse of cocaine, nicotine, methamphetamine, and morphine.
Topics: Animal Feed; Animals; Cocaine; Humans; Meat; Methamphetamine; Morphine; Nicotine; Substance-Related Disorders; United States | 2023 |
Effect of Club cell secretory proteins on the association of tobacco smoke and PAH co-exposure with lung function decline: A longitudinal observation of Chinese coke oven workers.
Topics: Coke; Epithelial Cells; Humans; Longitudinal Studies; Lung; Nicotiana; Nicotine; Occupational Exposure; Polycyclic Aromatic Hydrocarbons; Tobacco Smoke Pollution | 2023 |
Removal of residues of psychoactive substances during wastewater treatment, their occurrence in receiving river waters and environmental risk assessment.
Topics: Amphetamine; Biofilms; Bioreactors; Central Nervous System Agents; Cocaine; Dronabinol; Environmental Monitoring; Methadone; Nicotine; Rivers; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2023 |
Double dissociation of perirhinal nicotinic acetylcholine receptors and dopamine D2 receptors in modulation of object memory consolidation by nicotine, cocaine and their conditioned stimuli.
Topics: Animals; Cocaine; Male; Memory Consolidation; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Nicotinic | 2023 |
Occurrence and sources of residues of drugs of abuse in an urban aquifer: Chemical analysis and solute transport modelling.
Topics: Chromatography, Liquid; Cocaine; Gas Chromatography-Mass Spectrometry; Methadone; Nicotine; Tandem Mass Spectrometry; Water; Water Pollutants, Chemical | 2023 |
Assessing the impact of a major electronic music festival on the consumption patterns of illicit and licit psychoactive substances in a Mediterranean city using wastewater analysis.
Topics: Amphetamine; Analgesics, Opioid; Cocaine; Ethanol; Heroin; Holidays; Humans; Illicit Drugs; Music; N-Methyl-3,4-methylenedioxyamphetamine; Nicotine; Substance Abuse Detection; Substance-Related Disorders; Wastewater; Water Pollutants, Chemical | 2023 |
Tobacco/nicotine dependence as a risk factor for substance use disorders and related mental health conditions among cancer patients.
Topics: Alcoholic Intoxication; Alcoholism; Cocaine; Comorbidity; Humans; Marijuana Abuse; Mental Disorders; Mental Health; Neoplasms; Nicotiana; Nicotine; Risk Factors; Substance-Related Disorders; Tobacco Use Disorder | 2023 |
Nicotine modifies cocaine responding in a concurrent self-administration model.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Nicotine; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration; Substance-Related Disorders | 2023 |
A common profile of prefrontal cortical activation following exposure to nicotine- or chocolate-associated contextual cues.
Topics: Animals; Behavior, Animal; Cacao; Candy; Cell Count; Conditioning, Psychological; Cues; Learning; Male; Motor Activity; Neural Pathways; Neuronal Plasticity; Neurons; Nicotine; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Tobacco Use Disorder | 2001 |
Licking the habit.
Topics: Candy; Humans; Nicotine; Smoking Cessation; Tobacco Use Disorder; United States; United States Food and Drug Administration | 2002 |
[A new cause of false positives when analyzing expired air carbon monoxide].
Topics: Aged; Breath Tests; Candy; Carbon Monoxide; Central Nervous System Stimulants; Chewing Gum; False Positive Reactions; Humans; Male; Nicotine; Polymers; Polymethacrylic Acids; Polyvinyls; Smoking Cessation; Time Factors; Tobacco Use Cessation Devices | 2002 |
[Nicotine, a new alkaloid from the coca plant].
Topics: Alkaloids; Coca; Nicotine | 1958 |
The scientific basis of tobacco product regulation.
Topics: Advertising; Biomarkers; Biomedical Research; Candy; Consumer Product Safety; Global Health; Government Regulation; Harm Reduction; Humans; Maximum Allowable Concentration; Nicotine; Smoking; Smoking Prevention; Tobacco Industry; Tobacco Smoke Pollution; World Health Organization | 2007 |
Levels of mint and wintergreen flavorants: smokeless tobacco products vs. confectionery products.
Topics: Candy; Flavoring Agents; Mentha; Menthol; Nicotine; Oils, Volatile; Plant Extracts; Salicylates; Tobacco, Smokeless | 2010 |
Determination of caffeine, myosmine, and nicotine in chocolate by headspace solid-phase microextraction coupled with gas chromatography-tandem mass spectrometry.
Topics: Alkaloids; Beverages; Cacao; Caffeine; Calibration; Candy; Dairy Products; Food Contamination; Food Inspection; Food, Preserved; Gas Chromatography-Mass Spectrometry; Germany; Limit of Detection; Nicotine; Pigmentation; Solid Phase Microextraction; Tandem Mass Spectrometry; Volatilization | 2014 |
The effects of nicotine on conditioning, extinction, and reinstatement in humans.
Topics: Adult; Candy; Conditioning, Psychological; Connecticut; Extinction, Psychological; Female; Ganglionic Stimulants; Humans; Male; Nicotine; Reward; Students; Tobacco Use Disorder; Universities | 2018 |
The Effect of Flavored E-cigarettes on Murine Allergic Airways Disease.
Topics: Airway Remodeling; Animals; Bronchial Hyperreactivity; Bronchitis; Cola; Disease Models, Animal; E-Cigarette Vapor; Female; Flavoring Agents; Glycyrrhiza; Male; Mice; Mice, Inbred BALB C; Nicotine; Pyroglyphidae | 2019 |