nicotine has been researched along with clozapine in 52 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.92) | 18.7374 |
| 1990's | 6 (11.54) | 18.2507 |
| 2000's | 32 (61.54) | 29.6817 |
| 2010's | 12 (23.08) | 24.3611 |
| 2020's | 1 (1.92) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Keserü, GM | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Jia, L; Sun, H | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Giordanetto, F; Leach, AG; Zachariae, U | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Jayaraman, A; Kiba, H | 1 |
| Brioni, JD; Decker, MW; Kim, DJ; O'Neill, AB; Williams, JE | 1 |
| Oyewumi, LK | 1 |
| Chatterton, R; Plant, K; Sanderson, L; Van Leent, S | 1 |
| Freudenreich, O; McEvoy, JP; Wilson, WH | 1 |
| Lyon, ER | 1 |
| Bae, S; Choi, S; Kang, B; Kim, K; Park, T | 1 |
| Addy, N; Levin, ED | 1 |
| Markou, A; Semenova, S | 1 |
| Levin, ED; Rezvani, AH | 1 |
| Araki, H; Choshi, T; Gomita, Y; Hibino, S; Shibata, K; Suemaru, K; Umeda, K; Yasuda, K | 1 |
| Addy, NA; Levin, ED; Pocivavsek, A | 1 |
| Caldwell, DP; Levin, ED; Petro, A | 1 |
| Andersen, KK; Andreasen, JT; Mathiasen, L; Mirza, NR; Nielsen, EØ | 1 |
| Caldwell, DP; Levin, ED; Rezvani, AH | 1 |
| Icenogle, L; Levin, ED; Pocivavsek, A | 1 |
| Morales, M; Oz, M; Singhal, SK; Zhang, L | 1 |
| Dawson, E; Kholdebarin, E; Levin, ED; Rezvani, AH | 1 |
| Caldwell, DP; Levin, ED; Perraut, C | 1 |
| Hao, X; Levin, ED; Perraut, C; Roegge, CS | 1 |
| Caldwell, DP; Getachew, B; Hauser, SR; Hunter, C; Levin, ED; Rezvani, AH; Tizabi, Y | 1 |
| Hikichi, H; Maehara, S; Ohta, H; Okuda, S; Satow, A | 1 |
| Goktalay, G; Kayir, H; Uzbay, TI; Yildirim, M | 1 |
| Apon, J; Estrada, MN; Manchester, M; Northen, TR; Oppenheimer, SR; Potchoiba, MJ; Shriver, L; Siuzdak, G; Steenwyk, R; Woo, HK; Yanes, O | 1 |
| Brotherton, J; Cannady, R; Gotschlich, E; Kolia, N; Lau, E; Levin, ED; Wee, B; Weir, R | 1 |
| Ago, Y; Fukada, A; Kobayashi, H; Koda, K; Matsuda, T; Nishimura, M; Takuma, K; Yano, K | 1 |
| Dawe, GS; Deng, HM; Rajkumar, R; Suri, S | 1 |
| Bruchas, MR; Carlezon, WA; Hourguettes, NJ; Nygard, SK; Sobczak, GG | 1 |
| Feng, M; Li, M; Sparkman, NL; Sui, N | 1 |
| Abela, AR; Fletcher, PJ; Lê, AD; Li, Z | 1 |
| Bahji, A; Bousman, CA; Danilewitz, M; Honer, WG; Mathew, N; Rafizadeh, R; Schütz, CG; White, RF | 1 |
2 review(s) available for nicotine and clozapine
| Article | Year |
|---|---|
A review of the effects of nicotine on schizophrenia and antipsychotic medications.
Topics: Antipsychotic Agents; Auditory Perception; Chlorpromazine; Chronic Disease; Clozapine; Databases as Topic; Dopamine; Dose-Response Relationship, Drug; Frontal Lobe; Humans; Nicotine; Nucleus Accumbens; Prefrontal Cortex; Schizophrenia; Severity of Illness Index; Smoking Cessation | 1999 |
Effects of clozapine treatment on the improvement of substance use disorders other than nicotine in individuals with schizophrenia spectrum disorders: A systematic review and meta-analysis.
Topics: Antipsychotic Agents; Clozapine; Female; Humans; Male; Nicotine; Observational Studies as Topic; Schizophrenia; Substance-Related Disorders | 2023 |
50 other study(ies) available for nicotine and clozapine
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers.
Topics: Binding Sites; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Potassium Channel Blockers; Protein Binding; Protein Conformation | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Nicotine induced c-fos expression in the striatum is mediated mostly by dopamine D1 receptor and is dependent on NMDA stimulation.
Topics: Animals; Benzamides; Benzazepines; Clozapine; Corpus Striatum; Dizocilpine Maleate; Gene Expression Regulation; Genes, fos; Glutamates; Glutamic Acid; Male; Mecamylamine; Nicotine; Nucleus Accumbens; Piperazines; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Reward | 1994 |
Clozapine attenuates the discriminative stimulus properties of (-)-nicotine.
Topics: Alkaloids; Anabasine; Animals; Azocines; Chlorisondamine; Clozapine; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Flupenthixol; Lobeline; Male; Motor Activity; Nicotine; Quinolizines; Rats; Rats, Wistar; Stereoisomerism | 1994 |
Smoking cessation and clozapine side effects.
Topics: Antipsychotic Agents; Clozapine; Drug Interactions; Humans; Male; Middle Aged; Nicotine; Nicotinic Agonists; Schizophrenia; Smoking Cessation | 1998 |
Does clozapine affect smoking rates?
Topics: Clozapine; Drug Interactions; Humans; Nicotine; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Smoking; Smoking Prevention | 1998 |
Smoking and therapeutic response to clozapine in patients with schizophrenia.
Topics: Adult; Antipsychotic Agents; Brief Psychiatric Rating Scale; Clozapine; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Nicotine; Reference Values; Schizophrenia; Smoking; Treatment Outcome | 1999 |
Inhibition of nicotinic acetylcholine receptors and calcium channels by clozapine in bovine adrenal chromaffin cells.
Topics: Adrenal Glands; Alkenes; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels; Catecholamines; Cattle; Chlorpromazine; Chromaffin Cells; Clozapine; Dopamine Antagonists; Drug Interactions; Electrophysiology; GABA Antagonists; In Vitro Techniques; Nicotine; Nicotinic Antagonists; Norepinephrine; Potassium; Receptors, Nicotinic; Tritium | 2001 |
Nicotine interactions with haloperidol, clozapine and risperidone and working memory function in rats.
Topics: Animals; Antipsychotic Agents; Brain; Clozapine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Female; Haloperidol; Maze Learning; Memory, Short-Term; Neural Pathways; Nicotine; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Dopamine; Risperidone; Schizophrenia | 2002 |
Clozapine treatment attenuated somatic and affective signs of nicotine and amphetamine withdrawal in subsets of rats exhibiting hyposensitivity to the initial effects of clozapine.
Topics: Affective Symptoms; Amphetamine; Animals; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Male; Nicotine; Rats; Rats, Wistar; Reward; Substance Withdrawal Syndrome | 2003 |
Nicotine-antipsychotic drug interactions and attentional performance in female rats.
Topics: Animals; Antipsychotic Agents; Attention; Central Nervous System Stimulants; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Female; Haloperidol; Nicotine; Photic Stimulation; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Risperidone | 2004 |
Nicotine blocks apomorphine-induced disruption of prepulse inhibition of the acoustic startle in rats: possible involvement of central nicotinic alpha7 receptors.
Topics: Acoustic Stimulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Apomorphine; Central Nervous System; Clozapine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Haloperidol; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phencyclidine; Rats; Rats, Wistar; Receptors, Nicotinic; Reflex, Startle | 2004 |
Reversal of clozapine effects on working memory in rats with fimbria-fornix lesions.
Topics: Animals; Antipsychotic Agents; Clozapine; Female; Fornix, Brain; Hippocampus; Maze Learning; Memory, Short-Term; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley | 2005 |
Nicotine and clozapine actions on pre-pulse inhibition deficits caused by N-methyl-D-aspartate (NMDA) glutamatergic receptor blockade.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Female; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex, Startle | 2005 |
Nicotine and clozapine selectively reverse a PCP-induced deficit of PPI in BALB/cByJ but not NMRI mice: comparison with risperidone.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Female; Hallucinogens; Mice; Mice, Inbred BALB C; Neural Inhibition; Nicotine; Nicotinic Agonists; Phencyclidine; Reflex, Startle; Risperidone; Species Specificity | 2006 |
Chronic nicotine interactions with clozapine and risperidone and attentional function in rats.
Topics: Animals; Antipsychotic Agents; Attention; Behavior, Animal; Clozapine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Reaction Time; Risperidone; Sensory Thresholds; Signal Detection, Psychological | 2006 |
Ventral hippocampal alpha7 and alpha4beta2 nicotinic receptor blockade and clozapine effects on memory in female rats.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Antipsychotic Agents; Clozapine; Dihydro-beta-Erythroidine; Female; Hippocampus; Maze Learning; Memory; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2006 |
Antipsychotic clozapine inhibits the function of alpha7-nicotinic acetylcholine receptors.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Animals, Newborn; Antipsychotic Agents; Choline; Clozapine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Female; Hippocampus; In Vitro Techniques; Inhibitory Concentration 50; Male; Membrane Potentials; Microinjections; Nicotine; Nicotinic Agonists; Nootropic Agents; Oocytes; Patch-Clamp Techniques; Pyramidal Cells; Rats; Receptors, Nicotinic; Xenopus laevis | 2007 |
Nicotine and clozapine effects on attentional performance impaired by the NMDA antagonist dizocilpine in female rats.
Topics: Animals; Antipsychotic Agents; Attention; Clozapine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Nicotine; Nicotinic Agonists; Photic Stimulation; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Signal Detection, Psychological | 2008 |
Clozapine treatment reverses dizocilpine-induced deficits of pre-pulse inhibition of tactile startle response.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Drug Interactions; Female; Humans; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Schizophrenia | 2007 |
Histamine H1 receptor involvement in prepulse inhibition and memory function: relevance for the antipsychotic actions of clozapine.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Drug Interactions; Female; Histamine H1 Antagonists; Maze Learning; Memory; Nicotine; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Reflex, Startle | 2007 |
Chronic nicotine and dizocilpine effects on nicotinic and NMDA glutamatergic receptor regulation: interactions with clozapine actions and attentional performance in rats.
Topics: Alkaloids; Animals; Antipsychotic Agents; Attention; Azocines; Brain Chemistry; Bungarotoxins; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Nicotine; Nicotinic Agonists; Psychomotor Performance; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Signal Detection, Psychological | 2008 |
Antipsychotic property of a muscarinic receptor agonist in animal models for schizophrenia.
Topics: Animals; Antipsychotic Agents; Central Nervous System Stimulants; Clozapine; Dose-Response Relationship, Drug; Haloperidol; Hyperkinesis; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Muscarinic Agonists; Nicotine; Nicotinic Agonists; Oxotremorine; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenic Psychology | 2008 |
Clozapine inhibits development and expression of nicotine-induced locomotor sensitization in rats.
Topics: Animals; Clozapine; Dose-Response Relationship, Drug; Gene Expression Regulation; Male; Motor Activity; Neural Inhibition; Nicotine; Rats; Rats, Wistar | 2009 |
Nanostructure initiator mass spectrometry: tissue imaging and direct biofluid analysis.
Topics: Analytic Sample Preparation Methods; Animals; Brain; Clozapine; Ketamine; Male; Mass Spectrometry; Mice; Mice, Inbred BALB C; Nanostructures; Nicotine; Rats; Saliva; Xenobiotics | 2009 |
Nicotinic antagonist effects in the mediodorsal thalamic nucleus: regional heterogeneity of nicotinic receptor involvement in cognitive function.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Antipsychotic Agents; Clozapine; Cognition; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Maze Learning; Mediodorsal Thalamic Nucleus; Memory; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2009 |
Involvement of decreased muscarinic receptor function in prepulse inhibition deficits in mice reared in social isolation.
Topics: Acetylcholinesterase; Animals; Body Temperature; Cholinesterase Inhibitors; Clozapine; GABA Antagonists; Galantamine; Male; Mice; Microdialysis; Motor Activity; Muscarinic Agonists; Nicotine; Nicotinic Agonists; Oxotremorine; Parasympatholytics; Pirenzepine; Receptors, Muscarinic; Reflex, Startle; Sensory Gating; Social Isolation | 2011 |
Nicotine and clozapine cross-prime the locus coeruleus noradrenergic system to induce long-lasting potentiation in the rat hippocampus.
Topics: Animals; Antipsychotic Agents; Clozapine; Electrophysiology; Excitatory Postsynaptic Potentials; Hippocampus; Locus Coeruleus; Long-Term Potentiation; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley | 2013 |
Stress-Induced Reinstatement of Nicotine Preference Requires Dynorphin/Kappa Opioid Activity in the Basolateral Amygdala.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Basolateral Nuclear Complex; Clozapine; Conditioning, Operant; Drug-Seeking Behavior; Dynorphins; Extinction, Psychological; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Proto-Oncogene Proteins c-fos; Receptors, Opioid, kappa; Reinforcement, Psychology; Yohimbine | 2016 |
A drug-drug conditioning paradigm reveals multiple antipsychotic-nicotine interactions.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Clozapine; Conditioning, Classical; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Male; Motor Activity; Nicotine; Rats; Rats, Sprague-Dawley; Schizophrenia | 2017 |
Clozapine reduces nicotine self-administration, blunts reinstatement of nicotine-seeking but increases responding for food.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Conditioning, Operant; Drug-Seeking Behavior; Food; Haloperidol; Male; Motivation; Nicotine; Nicotinic Agonists; Rats; Reward; Self Administration | 2019 |