Page last updated: 2024-08-26

nicotine and cimetidine

nicotine has been researched along with cimetidine in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19903 (7.50)18.7374
1990's15 (37.50)18.2507
2000's14 (35.00)29.6817
2010's8 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ganapathy, V; Leibach, FH; Prasad, PD; Wu, X1
Fei, YJ; Ganapathy, V; Kekuda, R; Leibach, FH; Prasad, PD; Wang, H; Wu, X1
Giacomini, KM; Schaner, ME; Zhang, L1
Inui, KI; Masuda, S; Okuda, M; Saito, H; Urakami, Y1
Inui, K; Okuda, M; Saito, H; Urakami, Y1
Nezu, J; Oku, A; Sai, Y; Sakamoto, K; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H1
Chen, J; Conway, SJ; Ganapathy, V; Huang, W; Leibach, FH; Prasad, PD; Rajan, DP; Seth, P; Wu, X1
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H1
Conway, SJ; Ganapathy, V; George, RL; Huang, W; Leibach, FH; Wang, H; Wu, X1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Akazawa, M; Inui, K; Okuda, M; Saito, H; Urakami, Y1
Dansette, PM; Fontana, E; Poli, SM1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Araki, Y; Eto, K; Furuno, K; Gomita, Y1
Sitar, DS; Smyth, DD; Wong, LT1
Bendayan, R; Frecker, RC; Sellers, EM; Shaw, C; Sullivan, JT1
Bommer, M; Herz, A; Liebisch, D; Noble, EP1
DeMarco, GJ; Howard, PC; McCoy, GD1
Kusunoki, M; Tanaka, C; Taniyama, K1
Berkman, CE; Cashman, JR; Cashman, LE; Park, SB1
Seaton, MJ; Vesell, ES1
Bendayan, R; Frecker, RC; Kennedy, G; Sellers, EM1
Ea-Kim, L; Javellaud, J; Oudart, N1
Eidi, A; Eidi, M; Oryan, S; Parivar, K; Zarrindast, MR1
O'Donnell, MJ; Plaumann, JS; Rheault, MR1

Reviews

3 review(s) available for nicotine and cimetidine

ArticleYear
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
    Current drug metabolism, 2005, Volume: 6, Issue:5

    Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic

2005
Role of hepatic flavin-containing monooxygenase 3 in drug and chemical metabolism in adult humans.
    Chemico-biological interactions, 1995, Apr-28, Volume: 96, Issue:1

    Topics: Adult; Animals; Cimetidine; Gene Expression Regulation, Enzymologic; Humans; Liver; Nicotine; Oxidation-Reduction; Oxygenases; Safrole; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity; Swine

1995
Variables affecting nicotine metabolism.
    Pharmacology & therapeutics, 1993, Volume: 60, Issue:3

    Topics: Aging; Animals; Cimetidine; Dietary Proteins; Drug Interactions; Ethanol; Female; Genetic Variation; Humans; Nicotine; Pregnancy; Smoking; Species Specificity

1993

Trials

2 trial(s) available for nicotine and cimetidine

ArticleYear
Effect of cimetidine and ranitidine on the hepatic and renal elimination of nicotine in humans.
    European journal of clinical pharmacology, 1990, Volume: 38, Issue:2

    Topics: Adult; Cimetidine; Cotinine; Double-Blind Method; Humans; Injections, Intravenous; Liver; Male; Middle Aged; Nicotine; Random Allocation; Ranitidine

1990
Lack of effect of cimetidine on cigarette smoking.
    European journal of clinical pharmacology, 1993, Volume: 44, Issue:1

    Topics: Carbon Monoxide; Cimetidine; Cotinine; Double-Blind Method; Female; Humans; Male; Nicotine; Smoking; Smoking Cessation

1993

Other Studies

35 other study(ies) available for nicotine and cimetidine

ArticleYear
cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family.
    Biochemical and biophysical research communications, 1998, May-29, Volume: 246, Issue:3

    Topics: Amines; Amino Acid Sequence; Base Sequence; Biological Transport; Carrier Proteins; Chromosomes, Human, Pair 5; Cloning, Molecular; DNA, Complementary; Guanidines; Human Genome Project; Humans; Ions; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Organic Cation Transport Proteins; Pyridines; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Solute Carrier Family 22 Member 5; Symporters; Tetraethylammonium

1998
Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta.
    The Journal of biological chemistry, 1998, Jun-26, Volume: 273, Issue:26

    Topics: Amino Acid Sequence; Animals; Cloning, Molecular; DNA-Binding Proteins; HeLa Cells; Humans; Hydrogen-Ion Concentration; Molecular Sequence Data; Octamer Transcription Factor-3; Oocytes; Placenta; Protein Conformation; Rats; Transcription Factors; Xenopus laevis

1998
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa).
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1

    Topics: Carrier Proteins; Corticosterone; HeLa Cells; Humans; Membrane Proteins; Midazolam; Organic Cation Transporter 1; Permeability; Recombinant Proteins; Structure-Activity Relationship; Tetraethylammonium Compounds; Transfection

1998
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:2

    Topics: Animals; Base Sequence; Carrier Proteins; Cations; Cell Line; Cell Membrane; DNA Primers; Dogs; Kidney Tubules; Membrane Proteins; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Rats; Tetraethylammonium

1998
Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes.
    Biochimica et biophysica acta, 1999, Mar-04, Volume: 1417, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Buffers; Carrier Proteins; Cells, Cultured; Hydrogen-Ion Concentration; Levofloxacin; Membrane Proteins; Ofloxacin; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Potassium; Rats; Tetraethylammonium; Transfection; Xenopus laevis

1999
Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:2

    Topics: Animals; Biological Transport, Active; Carrier Proteins; Cell Line; Gene Expression; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Oocytes; Organic Cation Transport Proteins; Quinidine; RNA, Messenger; Symporters; Tetraethylammonium Compounds; Xenopus laevis

1999
Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:3

    Topics: Acetylcarnitine; Animals; Biological Transport, Active; Carnitine; Carrier Proteins; Humans; In Situ Hybridization; Kidney; Membrane Proteins; Mice; Myocardium; Organ Specificity; Organic Cation Transport Proteins; Placenta; Rats; RNA, Messenger; Solute Carrier Family 22 Member 5; Tetraethylammonium

1999
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism

1999
Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta.
    Biochimica et biophysica acta, 2000, Jun-01, Volume: 1466, Issue:1-2

    Topics: Amino Acid Sequence; Animals; Base Sequence; Carnitine; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Humans; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Organic Cation Transport Proteins; Placenta; Rats; RNA, Messenger; Solute Carrier Proteins; Structure-Activity Relationship; Symporters; Tetraethylammonium; Tissue Distribution

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 predominantly expressed in the human kidney.
    Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:7

    Topics: Alternative Splicing; Amino Acid Sequence; Base Sequence; Cations; Cell Line; Cloning, Molecular; DNA, Complementary; Genetic Variation; Humans; Kidney; Molecular Sequence Data; Organic Cation Transport Proteins; Organic Cation Transporter 2; Tetraethylammonium; Tissue Distribution; Transfection

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effects of exposure to standard- and nicotine-reduced-cigarette smoke on pharmacokinetics of theophylline and cimetidine in rats.
    Journal of pharmaceutical sciences, 1992, Volume: 81, Issue:11

    Topics: Animals; Chromatography, High Pressure Liquid; Cimetidine; Male; Nicotine; Rats; Rats, Wistar; Smoking; Theophylline

1992
Interference with renal organic cation transport by (-)- and (+)-nicotine at concentrations documented in plasma of habitual tobacco smokers.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:1

    Topics: Amantadine; Animals; Cimetidine; Cotinine; Humans; Kidney Cortex; Kidney Tubules; Male; Nicotine; Rats; Rats, Inbred Strains; Smoking; Stereoisomerism

1992
H1-histaminergic activation of catecholamine release by chromaffin cells.
    Biochemical pharmacology, 1988, Jan-15, Volume: 37, Issue:2

    Topics: Adrenal Medulla; Animals; Biological Transport, Active; Calcium; Catecholamines; Cattle; Cells, Cultured; Cimetidine; Clemastine; Histamine; Hormones; Kinetics; Muscarine; Nicotine; Norepinephrine; Ranitidine; Receptors, Histamine; Receptors, Histamine H1

1988
Characterization of hamster liver nicotine metabolism. I. Relative rates of microsomal C and N oxidation.
    Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16

    Topics: Animals; Chromatography, High Pressure Liquid; Cimetidine; Cotinine; Cricetinae; Cyanides; Cysteamine; Male; Mesocricetus; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Nicotine; Oxidation-Reduction; Papain; Peptide Hydrolases; Proadifen

1986
Inhibitory histamine H2-receptor in the guinea-pig urinary bladder.
    European journal of pharmacology, 1984, Oct-01, Volume: 105, Issue:1-2

    Topics: Acetylcholine; Animals; Calcium; Choline; Cimetidine; Diphenhydramine; Electric Stimulation; Female; Guinea Pigs; Histamine; Imidazoles; Impromidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Pyrilamine; Receptors, Histamine; Receptors, Histamine H2; Scopolamine; Tetrodotoxin; Urinary Bladder

1984
Reduction of the pressor response to nicotine in the guinea pigs by a histamine (H3) agonist is attenuated by an inhibitor of nitric oxide synthesis.
    Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:4

    Topics: Adrenalectomy; Animals; Arginine; Blood Pressure; Cimetidine; Guinea Pigs; Heart Rate; Histamine; Histamine Agonists; Histamine Antagonists; Male; Methylhistamines; NG-Nitroarginine Methyl Ester; Nicotine; Nitric Oxide Synthase; Piperidines

1996
Effects of histamine and cholinergic systems on memory retention of passive avoidance learning in rats.
    European journal of pharmacology, 2003, Mar-28, Volume: 465, Issue:1-2

    Topics: Acetylcholine; Animals; Avoidance Learning; Cimetidine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Memory; Muscarinic Antagonists; Nicotine; Pyrilamine; Rats; Rats, Wistar; Reaction Time; Receptors, Cholinergic; Receptors, Histamine; Retention, Psychology; Scopolamine

2003
Tetraethylammonium and nicotine transport by the Malpighian tubules of insects.
    Journal of insect physiology, 2006, Volume: 52, Issue:5

    Topics: Animals; Biological Transport; Carbon Radioisotopes; Chromatography, Thin Layer; Cimetidine; Female; In Vitro Techniques; Insecta; Male; Malpighian Tubules; Niacinamide; Nicotine; Quinidine; Rhodnius; Tetraethylammonium; Time Factors

2006