Compounds > nicotine
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nicotine and ar-r 17779

nicotine has been researched along with ar-r 17779 in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (66.67)29.6817
2010's5 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balestra, M; Blosser, J; DeCory, T; Gordon, J; Griffith, R; Gurley, D; Hale, G; Kover, A; Loch, J; Machulskis, A; Mack, R; Macor, J; Mullen, G; Murray, R; Napier, J; Phillips, E; Rosen, A; Sampognaro, A; Verhoest, P; Wu, E; Zhu, Y; Zongrone, J1
Enz, A; Feuerbach, D; Frederiksen, MU; Gentsch, C; Hurth, K; Müller, W; Nozulak, J; Roy, BL1
Grottick, AJ; Higgins, GA; Wyler, R1
Corrigall, WA; Grottick, AJ; Higgins, GA; Huwyler, J; Malherbe, P; Trube, G; Wyler, R1
Cherubini, E; Maggi, L; Sher, E1
Goodhead, LH; Mitchell, SN; Moss, S; Sharott, A1
Bennink, R; Boeckxstaens, GE; Cash, JL; de Jonge, WJ; Greaves, DR; Larosa, GJ; Snoek, SA; The, FO; van den Wijngaard, RM1
Bonaz, B1
Anderson, DJ; Bertrand, D; Bunnelle, W; Du, J; Gopalakrishnan, M; Marguerat, A; Surber, B; Surowy, C; Tribollet, E1
Elbaum, D; LaRosa, GJ; Lebre, MC; Tak, PP; van der Poll, T; van Maanen, MA; Vervoordeldonk, MJ1
Huang, LT; Lodge, D; Sherwood, JL; Sun, YJ; Wang, Y1
Boeckxstaens, GE; Bulmer, DC; de Jonge, WJ; Deeks, N; Lee, K; Skynner, M; Snoek, SA; Te Velde, AA; van der Zanden, EP; Verstege, MI1
Huang, YY; Kandel, DB; Kandel, ER; Levine, A1
Diebel, LN; Ginnebaugh, K; Liberati, DM; Tarras, SL1
Broekstra, N; Koopman, FA; Roescher, N; Tak, PP; Vervoordeldonk, MJ; Vosters, JL1

Other Studies

15 other study(ies) available for nicotine and ar-r 17779

ArticleYear
(-)-Spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazolidin-2'-one], a conformationally restricted analogue of acetylcholine, is a highly selective full agonist at the alpha 7 nicotinic acetylcholine receptor.
    Journal of medicinal chemistry, 2000, Nov-02, Volume: 43, Issue:22

    Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bridged-Ring Compounds; Hippocampus; In Vitro Techniques; Nicotinic Agonists; Oocytes; Prosencephalon; Radioligand Assay; Rats; Receptors, Nicotinic; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship; Xenopus

2000
Gamma-lactams--a novel scaffold for highly potent and selective alpha 7 nicotinic acetylcholine receptor agonists.
    Bioorganic & medicinal chemistry letters, 2009, Mar-01, Volume: 19, Issue:5

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Binding Sites; Brain; Humans; Lactams; Mice; Nicotinic Agonists; Protein Binding; Rabbits; Receptors, Nicotinic

2009
The alpha4beta2 agonist SIB 1765F, but not the alpha7 agonist AR-R 17779, cross-sensitises to the psychostimulant effects of nicotine.
    Psychopharmacology, 2000, Volume: 150, Issue:2

    Topics: Animals; Bridged-Ring Compounds; Male; Motor Activity; Nicotine; Nicotinic Agonists; Pyridines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Spiro Compounds

2000
Evidence that nicotinic alpha(7) receptors are not involved in the hyperlocomotor and rewarding effects of nicotine.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bridged-Ring Compounds; Electrophysiology; Humans; In Vitro Techniques; Ligands; Male; Motor Activity; Nicotine; Nicotinic Agonists; Oocytes; Pyridines; Pyrrolidines; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, Nicotinic; Reward; Self Administration; Spiro Compounds; Transfection; Xenopus laevis

2000
Regulation of GABA release by nicotinic acetylcholine receptors in the neonatal rat hippocampus.
    The Journal of physiology, 2001, Oct-01, Volume: 536, Issue:Pt 1

    Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Animals, Newborn; Bicuculline; Bridged-Ring Compounds; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Insecticides; Membrane Potentials; Nicotine; Nicotinic Agonists; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Nicotinic; Spiro Compounds

2001
Role of muscarinic receptors in the activation of the ventral subiculum and the consequences for dopamine release in the nucleus accumbens.
    European journal of pharmacology, 2003, Jan-24, Volume: 460, Issue:2-3

    Topics: Animals; Atropine; Bicuculline; Bridged-Ring Compounds; Carbachol; Cholinergic Agonists; Diamines; Dopamine; Hippocampus; Male; Microdialysis; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nucleus Accumbens; Oxotremorine; Pilocarpine; Pyridines; Rats; Receptors, Muscarinic; Spiro Compounds; Thiadiazoles; Tropanes

2003
Activation of the cholinergic anti-inflammatory pathway ameliorates postoperative ileus in mice.
    Gastroenterology, 2007, Volume: 133, Issue:4

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Bridged-Ring Compounds; Cells, Cultured; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation Therapy; Female; Gastric Emptying; Gastroenteritis; Ileus; Intestines; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; NF-kappa B; Nicotine; Nicotinic Agonists; Postoperative Complications; Receptors, Nicotinic; Spiro Compounds; Transcription, Genetic; Vagotomy; Vagus Nerve

2007
The cholinergic anti-inflammatory pathway and the gastrointestinal tract.
    Gastroenterology, 2007, Volume: 133, Issue:4

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Bridged-Ring Compounds; Central Nervous System; Cytokines; Disease Models, Animal; Electric Stimulation Therapy; Gastric Emptying; Gastroenteritis; Humans; Ileus; Intestines; Macrophages, Peritoneal; NF-kappa B; Nicotine; Nicotinic Agonists; Postoperative Complications; Receptors, Nicotinic; Reflex; Spiro Compounds; Transcription, Genetic; Vagotomy; Vagus Nerve

2007
[3H]A-585539 [(1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo[2.2.1]heptane], a novel high-affinity alpha7 neuronal nicotinic receptor agonist: radioligand binding characterization to rat and human brain.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 324, Issue:1

    Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Bungarotoxins; Cell Line; Humans; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Spiro Compounds

2008
Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice.
    Arthritis and rheumatism, 2009, Volume: 60, Issue:1

    Topics: Administration, Oral; alpha7 Nicotinic Acetylcholine Receptor; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Bridged-Ring Compounds; Cartilage; Disease Models, Animal; Injections, Intraperitoneal; Macrophages; Male; Mice; Mice, Inbred DBA; Nicotine; Nicotinic Agonists; Parasympathetic Nervous System; Receptors, Nicotinic; Spiro Compounds; Synovial Membrane; Synovitis; Tumor Necrosis Factor-alpha; Vagus Nerve

2009
Activation of presynaptic alpha7 nicotinic receptors evokes an excitatory response in hippocampal CA3 neurones in anaesthetized rats: an in vivo iontophoretic study.
    British journal of pharmacology, 2010, Feb-01, Volume: 159, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Aconitine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; D-Aspartic Acid; Glutamic Acid; Hippocampus; Male; N-Methylaspartate; Neurons; Nicotine; Nicotinic Antagonists; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Presynaptic; Spiro Compounds

2010
Selective alpha7 nicotinic acetylcholine receptor agonists worsen disease in experimental colitis.
    British journal of pharmacology, 2010, Volume: 160, Issue:2

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bridged-Ring Compounds; Cells, Cultured; Colitis; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Macrophages; Mice; Mice, Inbred C57BL; NF-kappa B; Nicotine; Nicotinic Agonists; Receptors, Nicotinic; Severity of Illness Index; Spiro Compounds

2010
Nicotine primes the effect of cocaine on the induction of LTP in the amygdala.
    Neuropharmacology, 2013, Volume: 74

    Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amygdala; Animals; Bridged-Ring Compounds; Cocaine; Dihydro-beta-Erythroidine; Dopamine Uptake Inhibitors; Drug Synergism; Histone Deacetylase Inhibitors; Hydroxamic Acids; Long-Term Potentiation; Male; Mice; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Spiro Compounds; Time Factors; Vorinostat

2013
Pharmacologic stimulation of the nicotinic anti-inflammatory pathway modulates gut and lung injury after hypoxia-reoxygenation injury.
    Surgery, 2013, Volume: 154, Issue:4

    Topics: Bridged-Ring Compounds; Cell Hypoxia; HT29 Cells; Humans; Interleukin-6; Intestinal Mucosa; Intestines; Lung Injury; Nicotine; Reperfusion Injury; Spiro Compounds; Tumor Necrosis Factor-alpha; Vagus Nerve

2013
Cholinergic anti-inflammatory pathway in the non-obese diabetic mouse model.
    Oral diseases, 2015, Volume: 21, Issue:7

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bridged-Ring Compounds; Chemokine CCL2; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Inflammation; Islets of Langerhans; Mice; Mice, Inbred NOD; Nicotine; Pancreatitis; Saliva; Salivary Glands; Salivation; Sjogren's Syndrome; Spiro Compounds; Tumor Necrosis Factor-alpha; Vagotomy

2015