Page last updated: 2024-08-26

nicotine and anatabine

nicotine has been researched along with anatabine in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.76)18.7374
1990's1 (2.38)18.2507
2000's9 (21.43)29.6817
2010's20 (47.62)24.3611
2020's10 (23.81)2.80

Authors

AuthorsStudies
Curtis, MA; Lin, SX; Sperry, J1
Riebe, M; Westphal, K1
Benowitz, NL; Jacob, P; Shulgin, AT; Yu, L1
Galston, AW; Ingersoll, R; Tiburcio, AF1
Benowitz, NL; Hall, S; Hatsukami, D; Jacob, P; Severson, H; Yu, L1
Chintapakorn, Y; Hamill, JD1
Cashman, JR; Denton, TT; Zhang, X1
Carmella, SG; Hatsukami, DK; Hecht, SS; Jensen, J; Le, C; Link, CA; Losey, L; Murphy, SE; Puumala, SS1
Bartholomeusz, TA; Felpin, FX; Gillet, F; Lebreton, J; Mesnard, F; Molinié, R; Robins, RJ; Roscher, A1
Ayers, JT; Crooks, PA; Dwoskin, LP; Xu, R1
Hsieh, SH; Huang, HY1
Chen, C; Liu, B; Su, Q; Wu, D1
Hashimoto, T; Shoji, T1
Dalton, HL; DeBoer, KD; Edward, FJ; Hamill, JD1
Grata, E; Marclay, F; Perrenoud, L; Saugy, M1
Fleckenstein, AE; Miller, EI; Nielsen, SM; Vieira-Brock, PL; Wilkins, DG1
Dewey, RE; Xie, J1
Caine, SB; Fivel, PA; Kohut, SJ; Mello, NK1
Caine, SB; Collins, GT; Lanier, RK; Mello, NK; Thomsen, M; Wright, C1
Blount, BC; Feng, J; McGuffey, JE; Miller, S; Rehmani, IJ; Wang, L; Wei, B1
Bernert, JT; Blount, BC; McGuffey, JE; Morrow, JC; Wang, L; Wei, B; Xia, B1
Goossens, A; Hayashida, M; Ito, S; Minami, S; Morita, M; Moriyama, Y; Moriyasu, M; Omote, H; Shitan, N; Sugiyama, A; Takanashi, K; Yazaki, K1
Jackson, KJ; Marusich, JA; Thomas, BF; Wiley, JL1
Fischer, L; Jantos, R; Mikus, F; Skopp, G1
Banal, A; Cao, Q; Harris, AC; LeSage, MG; Muelken, P; Schmidt, CE; Tally, L1
Gerber, JP; Tscharke, BJ; White, JM1
Donny, EC; Hatsukami, DK; Murphy, SE; Thomson, NM; von Weymarn, LB1
Bergman, J; Desai, RI; Doyle, MR; Withey, SL1
Geyer, H; Hedeland, M; Piper, T; Schänzer, W; Thevis, M; Thomas, A; Tretzel, L1
Bergman, J; Desai, RI; Kohut, SJ; Sullivan, KA1
Appel, H; Cocroft, R; Cossio-Rodríguez, R; Niemeyer, HM; Penna, M; Pinto, CF; Torrico-Bazoberry, D1
Hoeng, J; Koshibu, K; Peitsch, MC; Veljkovic, E; Xia, W1
Kotova, TI; Liu, H; Timko, MP1
Kem, WR; Keshwah, S; Rouchaud, A; Xing, H1
Abdelaziz, A; Bade, R; Gerber, C; Ghetia, M; Tscharke, BJ; White, JM1
Eaglesham, G; Gerber, C; Li, J; O'Brien, JW; Reeks, T; Shimko, KM; Thai, PK; Thomas, KV; Thompson, J; Tscharke, BJ; Zheng, Q1
Cai, B; Cai, K; Gao, W; Lei, B; Lin, Y; Pan, W; Wang, A; Wang, F; Yin, R; Zhao, H1
Callahan, PM; Hoeng, J; Koshibu, K; Peitsch, MC; Terry, AV1
Hawkey, AB; Hoeng, J; Koshibu, K; Levin, ED; Peitsch, MC1
Bendik, PB; Blount, BC; Feng, J; Pine, BN; Rutt, SM; Sosnoff, CS; Wang, L; Zhu, W1
Abd-Eldayem, AM; Abd-Elhafeez, HH; Abdo, W; Ali, E; Alnasser, SM; Dmerdash, M; Hakamy, A; Haziri, I; Soliman, SA1
Bovet, L; De Palo, D; Goepfert, S; Guy, PA; Hilfiker, A; Ivanov, NV; Kaminski, KP; Lang, G; Laparra, H; Laszlo, C; Schwaar, J; Sierro, N1

Reviews

2 review(s) available for nicotine and anatabine

ArticleYear
Pyridine alkaloids with activity in the central nervous system.
    Bioorganic & medicinal chemistry, 2020, 12-15, Volume: 28, Issue:24

    Topics: Alkaloids; Amphibians; Animals; Bacteria; Central Nervous System Diseases; Fungi; Nicotine; Plants; Pyridines; Receptors, Nicotinic

2020
Molecular genetics of alkaloid biosynthesis in Nicotiana tabacum.
    Phytochemistry, 2013, Volume: 94

    Topics: Alkaloids; Biosynthetic Pathways; Gene Expression Regulation, Plant; Methyltransferases; Molecular Structure; Nicotiana; Nicotine; Nitrosamines; Plant Proteins; Pyridines

2013

Trials

2 trial(s) available for nicotine and anatabine

ArticleYear
Anabasine and anatabine as biomarkers for tobacco use during nicotine replacement therapy.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2002, Volume: 11, Issue:12

    Topics: Adult; Alkaloids; Anabasine; Biomarkers; Chewing Gum; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nicotine; Probability; Prospective Studies; Pyridines; Reference Values; Sensitivity and Specificity; Severity of Illness Index; Smoking; Tobacco Use Cessation; Tobacco Use Disorder; Tobacco, Smokeless; Treatment Outcome

2002
A comparison of urinary biomarkers of tobacco and carcinogen exposure in smokers.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2004, Volume: 13, Issue:10

    Topics: Adult; Alkaloids; Biomarkers; Carcinogens; Endpoint Determination; Environmental Exposure; Female; Ganglionic Stimulants; Humans; Male; Nicotine; Nitrosamines; Polycyclic Aromatic Hydrocarbons; Pyridines; Reproducibility of Results; Smoking; Smoking Cessation; Urinalysis

2004

Other Studies

38 other study(ies) available for nicotine and anatabine

ArticleYear
Studies on the induction of sister-chromatid exchanges in Chinese hamster ovary cells by various tobacco alkaloids.
    Mutation research, 1983, Volume: 124, Issue:3-4

    Topics: Alkaloids; Animals; Benzo(a)pyrene; Benzopyrenes; Cell Line; Cricetinae; Cricetulus; Crossing Over, Genetic; Female; Insecticides; Methylnitronitrosoguanidine; Mutagenicity Tests; Mutagens; Mutation; Nicotiana; Nicotine; Ovary; Plants, Toxic; Pyridines; Sister Chromatid Exchange

1983
Minor tobacco alkaloids as biomarkers for tobacco use: comparison of users of cigarettes, smokeless tobacco, cigars, and pipes.
    American journal of public health, 1999, Volume: 89, Issue:5

    Topics: Adult; Alkaloids; Anabasine; Biomarkers; Cotinine; Humans; Male; Middle Aged; Nicotiana; Nicotine; Nicotinic Agonists; Plants, Toxic; Pyridines; Reproducibility of Results; Smoking; Substance Abuse Detection; Time Factors; Tobacco Use Disorder

1999
Modified alkaloid pattern in developing tobacco callus.
    Plant science : an international journal of experimental plant biology, 1985, Volume: 38

    Topics: Alkaloids; Anabasine; Carboxylic Acids; Citric Acid; Culture Media; Culture Techniques; Fumarates; Malates; Nicotiana; Nicotine; Plant Roots; Plants, Toxic; Pyridines; Pyrrolidines; Pyruvic Acid

1985
Antisense-mediated down-regulation of putrescine N-methyltransferase activity in transgenic Nicotiana tabacum L. can lead to elevated levels of anatabine at the expense of nicotine.
    Plant molecular biology, 2003, Volume: 53, Issue:1-2

    Topics: Alkaloids; Culture Techniques; DNA, Antisense; Down-Regulation; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Methyltransferases; Models, Biological; Nicotiana; Nicotine; Plant Roots; Plants, Genetically Modified; Pyridines; Regeneration

2003
Nicotine-related alkaloids and metabolites as inhibitors of human cytochrome P-450 2A6.
    Biochemical pharmacology, 2004, Feb-15, Volume: 67, Issue:4

    Topics: Alkaloids; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Mixed Function Oxygenases; Nicotine; Oxidoreductases, N-Demethylating; Pyridines; Smoking

2004
Stereoselectivity of the demethylation of nicotine piperidine homologues by Nicotiana plumbaginifolia cell suspension cultures.
    Phytochemistry, 2005, Volume: 66, Issue:16

    Topics: Alkaloids; Anabasine; Cells, Cultured; Kinetics; Methylation; Molecular Structure; Nicotiana; Nicotine; Pyridines

2005
A general procedure for the enantioselective synthesis of the minor tobacco alkaloids nornicotine, anabasine, and anatabine.
    The AAPS journal, 2005, Oct-31, Volume: 7, Issue:3

    Topics: Alkaloids; Anabasine; Nicotiana; Nicotine; Pyridines; Stereoisomerism

2005
Analyses of tobacco alkaloids by cation-selective exhaustive injection sweeping microemulsion electrokinetic chromatography.
    Journal of chromatography. A, 2007, Sep-14, Volume: 1164, Issue:1-2

    Topics: Alkaloids; Anabasine; Chromatography, Micellar Electrokinetic Capillary; Molecular Structure; Nicotiana; Nicotine; Pyridines; Reproducibility of Results

2007
Enantiomeric analysis of anatabine, nornicotine and anabasine in commercial tobacco by multi-dimensional gas chromatography and mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Apr-01, Volume: 865, Issue:1-2

    Topics: Alkaloids; Anabasine; Gas Chromatography-Mass Spectrometry; Nicotiana; Nicotine; Pyridines; Stereoisomerism

2008
Why does anatabine, but not nicotine, accumulate in jasmonate-elicited cultured tobacco BY-2 cells?
    Plant & cell physiology, 2008, Volume: 49, Issue:8

    Topics: Alkaloids; Cells, Cultured; Cyclopentanes; Down-Regulation; Gene Expression Regulation, Plant; Molecular Structure; Nicotiana; Nicotine; Oxidoreductases; Oxylipins; Plant Proteins; Plant Roots; Pyridines; RNA Interference

2008
RNAi-mediated down-regulation of ornithine decarboxylase (ODC) leads to reduced nicotine and increased anatabine levels in transgenic Nicotiana tabacum L.
    Phytochemistry, 2011, Volume: 72, Issue:4-5

    Topics: Alkaloids; Molecular Structure; Nicotiana; Nicotine; Ornithine Decarboxylase; Plant Roots; Plants, Genetically Modified; Pyridines; RNA Interference; Seeds

2011
A one-year monitoring of nicotine use in sport: frontier between potential performance enhancement and addiction issues.
    Forensic science international, 2011, Dec-10, Volume: 213, Issue:1-3

    Topics: Alkaloids; Anabasine; Athletes; Chromatography, Liquid; Cotinine; Doping in Sports; Humans; Mass Spectrometry; Nicotine; Performance-Enhancing Substances; Pyridines; Smoking; Spectrometry, Mass, Electrospray Ionization; Tobacco, Smokeless

2011
Simultaneous quantification of nicotine and metabolites in rat brain by liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Nov-15, Volume: 879, Issue:30

    Topics: Alkaloids; Anabasine; Animals; Biomarkers; Brain Chemistry; Chromatography, Liquid; Cotinine; Linear Models; Male; Nicotine; Pyridines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2011
Anatabine significantly decreases nicotine self-administration.
    Experimental and clinical psychopharmacology, 2014, Volume: 22, Issue:1

    Topics: Alkaloids; Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Macaca mulatta; Male; Nicotine; Pyridines; Reinforcement Schedule; Self Administration

2014
Nicotine-like behavioral effects of the minor tobacco alkaloids nornicotine, anabasine, and anatabine in male rodents.
    Experimental and clinical psychopharmacology, 2014, Volume: 22, Issue:1

    Topics: Alkaloids; Anabasine; Animals; Behavior, Animal; Discrimination Learning; Dose-Response Relationship, Drug; Male; Mice; Nicotiana; Nicotine; Pyridines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Substance Withdrawal Syndrome

2014
A high-throughput robotic sample preparation system and HPLC-MS/MS for measuring urinary anatabine, anabasine, nicotine and major nicotine metabolites.
    Clinica chimica acta; international journal of clinical chemistry, 2014, Sep-25, Volume: 436

    Topics: Alkaloids; Anabasine; Analytic Sample Preparation Methods; Animals; Chromatography, High Pressure Liquid; Cryopreservation; Escherichia coli; Glucuronidase; Helix, Snails; Humans; Hydrolysis; Limit of Detection; Nicotine; Pyridines; Robotics; Smoking; Tandem Mass Spectrometry; Temperature; Urinalysis

2014
Validation of a LC-MS/MS method for quantifying urinary nicotine, six nicotine metabolites and the minor tobacco alkaloids--anatabine and anabasine--in smokers' urine.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Alkaloids; Anabasine; Chromatography, Liquid; Cotinine; Humans; Nicotine; Pyridines; Smoking; Tandem Mass Spectrometry

2014
Involvement of the leaf-specific multidrug and toxic compound extrusion (MATE) transporter Nt-JAT2 in vacuolar sequestration of nicotine in Nicotiana tabacum.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Acetates; Alkaloids; Anabasine; Cell Membrane; Cyclopentanes; Flavonoids; Gene Expression Profiling; Nicotiana; Nicotine; Oxylipins; Phylogeny; Plant Cells; Plant Leaves; Plant Proteins; Plant Roots; Pyridines; RNA, Messenger; Saccharomyces cerevisiae; Up-Regulation; Vacuoles

2014
Determination of behaviorally effective tobacco constituent doses in rats.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2015, Volume: 17, Issue:3

    Topics: Alkaloids; Animals; Cotinine; Dose-Response Relationship, Drug; Male; Motor Activity; Nicotiana; Nicotine; Pyridines; Rats; Rats, Sprague-Dawley

2015
Simultaneous quantification of tobacco alkaloids and major phase I metabolites by LC-MS/MS in human tissue.
    International journal of legal medicine, 2015, Volume: 129, Issue:2

    Topics: Alkaloids; Anabasine; Animals; Brain Chemistry; Cattle; Chickens; Chromatography, Liquid; Ganglionic Stimulants; Humans; Liver; Lung; Muscle, Skeletal; Nicotiana; Nicotine; Pyridines; Smoking; Solid Phase Extraction; Swine; Tandem Mass Spectrometry; Tissue Distribution

2015
Effects of nicotine and minor tobacco alkaloids on intracranial-self-stimulation in rats.
    Drug and alcohol dependence, 2015, Aug-01, Volume: 153

    Topics: Alkaloids; Anabasine; Animals; Brain; Cotinine; Male; Nicotine; Pyridines; Rats; Self Stimulation

2015
Estimates of tobacco use by wastewater analysis of anabasine and anatabine.
    Drug testing and analysis, 2016, Volume: 8, Issue:7

    Topics: Alkaloids; Anabasine; Chromatography, Liquid; Cotinine; Humans; Limit of Detection; Mass Spectrometry; Nicotine; Pyridines; Solid Phase Extraction; Tobacco Use; Wastewater; Water Pollutants, Chemical

2016
Quantitation of the Minor Tobacco Alkaloids Nornicotine, Anatabine, and Anabasine in Smokers' Urine by High Throughput Liquid Chromatography-Mass Spectrometry.
    Chemical research in toxicology, 2016, Mar-21, Volume: 29, Issue:3

    Topics: Adolescent; Alkaloids; Anabasine; Chromatography, High Pressure Liquid; Humans; Molecular Structure; Nicotiana; Nicotine; Pyridines; Smoking; Tandem Mass Spectrometry

2016
Nicotinic effects of tobacco smoke constituents in nonhuman primates.
    Psychopharmacology, 2016, Volume: 233, Issue:10

    Topics: Alkaloids; Anabasine; Animals; Behavior, Addictive; Behavior, Animal; Cotinine; Dose-Response Relationship, Drug; Male; Nicotiana; Nicotine; Pyridines; Saimiri; Smoke

2016
Fully automated determination of nicotine and its major metabolites in whole blood by means of a DBS online-SPE LC-HR-MS/MS approach for sports drug testing.
    Journal of pharmaceutical and biomedical analysis, 2016, May-10, Volume: 123

    Topics: Alkaloids; Anabasine; Automation; Chromatography, Liquid; Cotinine; Doping in Sports; Dried Blood Spot Testing; Electronic Nicotine Delivery Systems; Female; Humans; Male; Nicotine; Online Systems; Pyridines; Reproducibility of Results; Solid Phase Extraction; Sports; Substance Abuse Detection; Tandem Mass Spectrometry

2016
Influence of experimental history on nicotine self-administration in squirrel monkeys.
    Psychopharmacology, 2016, Volume: 233, Issue:12

    Topics: Alkaloids; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Eating; Male; Nicotine; Pyridines; Reinforcement, Psychology; Saimiri; Self Administration

2016
Chemical Responses of Nicotiana tabacum (Solanaceae) Induced by Vibrational Signals of a Generalist Herbivore.
    Journal of chemical ecology, 2019, Volume: 45, Issue:8

    Topics: Alkaloids; Anabasine; Animals; Gas Chromatography-Mass Spectrometry; Herbivory; Host-Parasite Interactions; Larva; Lepidoptera; Linear Models; Nicotiana; Nicotine; Principal Component Analysis; Pyridines; Vibration

2019
Neurobehavioral effects of selected tobacco constituents in rodents following subchronic administration.
    European journal of pharmacology, 2019, Dec-15, Volume: 865

    Topics: Alkaloids; Animals; Antidepressive Agents; Behavior, Animal; Coumaric Acids; Depression; Male; Memory; Mice, Inbred BALB C; Mice, Inbred C57BL; Nicotiana; Nicotine; Nootropic Agents; Pyridines; Rats, Long-Evans

2019
Increased Leaf Nicotine Content by Targeting Transcription Factor Gene Expression in Commercial Flue-Cured Tobacco (
    Genes, 2019, 11-14, Volume: 10, Issue:11

    Topics: Acetates; Alkaloids; Anabasine; Cyclopentanes; Ethylenes; Gene Expression Regulation, Plant; Helix-Loop-Helix Motifs; Nicotiana; Nicotine; Oxylipins; Plant Growth Regulators; Plant Leaves; Plants, Genetically Modified; Promoter Regions, Genetic; Pyridines; Tobacco Products; Transcription Factors

2019
A Pharmacological Comparison of Two Isomeric Nicotinic Receptor Agonists: The Marine Toxin Isoanatabine and the Tobacco Alkaloid Anatabine.
    Marine drugs, 2020, Feb-11, Volume: 18, Issue:2

    Topics: Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Animals; Humans; Isomerism; Marine Toxins; Nicotiana; Nicotine; Nicotinic Agonists; Pyridines; Receptors, Nicotinic

2020
Anabasine-based measurement of cigarette consumption using wastewater analysis.
    Drug testing and analysis, 2020, Volume: 12, Issue:9

    Topics: Alkaloids; Anabasine; Australia; Cigarette Smoking; Cotinine; Female; Humans; Male; Nicotine; Pyridines; Tobacco Products; Tobacco Use Cessation Devices; Wastewater

2020
Determination of anabasine, anatabine, and nicotine biomarkers in wastewater by enhanced direct injection LC-MS/MS and evaluation of their in-sewer stability.
    The Science of the total environment, 2020, Nov-15, Volume: 743

    Topics: Alkaloids; Anabasine; Australia; Biomarkers; Chromatography, Liquid; Cotinine; Electronic Nicotine Delivery Systems; Nicotine; Pyridines; Smoking Cessation; Tandem Mass Spectrometry; Tobacco Use Cessation Devices; Wastewater

2020
Chiral determination of nornicotine, anatabine and anabasine in tobacco by achiral gas chromatography with (1S)-(-)-camphanic chloride derivatization: Application to enantiomeric profiling of cultivars and curing processes.
    Journal of chromatography. A, 2020, Aug-30, Volume: 1626

    Topics: Alkaloids; Anabasine; Bridged-Ring Compounds; Chlorides; Chromatography, Gas; Lactones; Nicotiana; Nicotine; Pyridines; Stereoisomerism

2020
Differential effects of alkaloids on memory in rodents.
    Scientific reports, 2021, 05-10, Volume: 11, Issue:1

    Topics: Alkaloids; Animals; Cotinine; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Mice; Nicotine; Nicotinic Agonists; Pyridines; Rats; Receptors, Nicotinic; Scopolamine; Spatial Memory

2021
Subchronic effects of plant alkaloids on anxiety-like behavior in zebrafish.
    Pharmacology, biochemistry, and behavior, 2021, Volume: 207

    Topics: Alkaloids; Anabasine; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Buspirone; Carbolines; Cotinine; Disease Models, Animal; Female; Harmine; Humans; Male; Nicotine; Pyridines; Solanaceae; Zebrafish

2021
Anabasine and Anatabine Exposure Attributable to Cigarette Smoking: National Health and Nutrition Examination Survey (NHANES) 2013-2014.
    International journal of environmental research and public health, 2022, 08-08, Volume: 19, Issue:15

    Topics: Adult; Alkaloids; Anabasine; Biomarkers; Cigarette Smoking; Cotinine; Humans; Nicotiana; Nicotine; Nutrition Surveys; Pyridines

2022
Anatabine attenuates ovalbumin-induced asthma via oxidative stress and inflammation mitigation and Nrf2/HO-1 signaling upregulation in rats.
    Life sciences, 2022, Nov-01, Volume: 308

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Antioxidants; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Heme Oxygenase (Decyclizing); Inflammation; Lung; NF-E2-Related Factor 2; Nicotine; Nitric Oxide Synthase Type II; Ovalbumin; Oxidative Stress; Pyridines; Rats; Up-Regulation

2022
Suppression of pyrrolidine ring biosynthesis and its effects on gene expression and subsequent accumulation of anatabine in leaves of tobacco (N. tabacum L.).
    BMC genomics, 2023, Sep-04, Volume: 24, Issue:1

    Topics: Alkaloids; Gene Expression; Nicotiana; Nicotine; Plant Leaves; Pyrrolidines

2023