Page last updated: 2024-08-26

nicotine and amyloid beta-peptides

nicotine has been researched along with amyloid beta-peptides in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.70)18.2507
2000's20 (74.07)29.6817
2010's5 (18.52)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Munekata, E; Takenouchi, T1
Freidland, RP; Menon, NK; Peng, L; Salomon, AR; Shao, H; Yang, J; Zagorski, MG; Zeng, H; Zhang, Y1
Akaike, A; Honda, K; Kihara, T; Kume, T; Nakamizo, T; Sawada, H; Shibasaki, H; Shimohama, S1
Mizuno, M; Nabeshima, T; Olariu, A; Ren, XH; Tran, MH; Yamada, K1
Baláspiri, L; Mák, M; Skribanek, Z1
Bednar, I; Court, J; Hall, R; Hellström-Lindahl, E; Johnson, M; Lee, M; Mousavi, M; Nordberg, A; Perry, E1
Lee, DH; Wang, HY1
Freir, DB; Herron, CE1
Dickerson, TJ; Janda, KD1
Alés, E; Arias, E; Cano-Abad, MF; Gabilan, NH; García, AG; López, MG; Villarroya, M1
Allsop, D; El-Agnaf, OM; Fullwood, NJ; Gibson, GL; Huckerby, TN; Moore, SA; Tabner, BJ; Turnbull, S1
Hellström-Lindahl, E; Mousavi, M; Nordberg, A; Ravid, R1
Damberg, P; Danielsson, J; Gräslund, A; Jarvet, J1
Bednar, I; Court, J; Hellström-Lindahl, E; Keverne, J; Lee, M; Marutle, A; Nordberg, A; Perry, E; Svedberg, M; Thomas, A1
Bell, KA; Dineley, KT; O'Riordan, KJ; Sweatt, JD1
Chen, MF; Lee, TJ; Long, C; Si, ML; Yang, DI1
Hedberg, MM; Nordberg, A; Svedberg, MM; Unger, C; Yu, WF1
Iwata, N; Mizoguchi, H; Mouri, A; Nabeshima, T; Noda, Y; Saido, TC; Wang, D; Wang, MW; Zou, LB1
Chen, Q; He, W; Huang, YY; Li, FL; Liu, NQ; Liu, Q; Lu, ZB; Qin, C; Zhang, J; Zhao, BL; Zhu, H1
Kaliszan, R; Radecka, H; Radecki, J; Szymańska, I1
Anand, K; Lue, LF; Reid, RT; Sabbagh, MN; Stadnick, T; Walker, DG1
Burza, A; Grabowska, I; Kaliszan, M; Kaliszan, R; Radecka, H; Radecki, J1
Bao, F; Klein, WL; Lacor, PN; Marutle, A; Nordberg, A; Wicklund, L1
Ferreira, ST; Juliano, L; Juliano, MA; Magdesian, MH; Nery, AA; Sathler, LB; Trujillo, CA; Ulrich, H1
Govoni, S; Grilli, M; Marchi, M; Mura, E; Olivero, G; Preda, S; Salamone, A; Zappettini, S1
Asahi, T; Ju, Y; Sawamura, N1
Akdas, YE; Andres-Alonso, M; Anni, D; Fejtova, A; Guhathakurta, D; Huth, T; Klueva, J; Weiss, EM; Zeitler, S1

Other Studies

27 other study(ies) available for nicotine and amyloid beta-peptides

ArticleYear
Inhibitory effects of beta-amyloid peptides on nicotine-induced Ca2+ influx in PC12h cells in culture.
    Neuroscience letters, 1994, May-23, Volume: 173, Issue:1-2

    Topics: Amino Acid Sequence; Amyloid beta-Peptides; Animals; Calcium; Cells, Cultured; Cytoplasm; Molecular Sequence Data; Nicotine; Nifedipine; PC12 Cells; Peptide Fragments; Potassium; Rats; Receptors, Nicotinic; Substance P

1994
Nicotine and amyloid formation.
    Biological psychiatry, 2001, Feb-01, Volume: 49, Issue:3

    Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Brain; Humans; Magnetic Resonance Spectroscopy; Nicotine; Peptide Fragments; Protein Conformation; Receptors, Nicotinic; Structure-Activity Relationship

2001
alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity.
    The Journal of biological chemistry, 2001, Apr-27, Volume: 276, Issue:17

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Androstadienes; Animals; Blotting, Western; Bungarotoxins; Calcineurin; Cell Death; Cells, Cultured; Cerebral Cortex; Chromones; Enzyme Inhibitors; Glutamic Acid; Immunoblotting; Models, Biological; Morpholines; Neurons; Nicotine; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-fyn; Rats; Receptors, Nicotinic; Signal Transduction; Wortmannin

2001
Amyloid beta-peptide induces nitric oxide production in rat hippocampus: association with cholinergic dysfunction and amelioration by inducible nitric oxide synthase inhibitors.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:8

    Topics: Acetylcholine; Amyloid beta-Peptides; Animals; Cerebral Ventricles; Chemotherapy, Cancer, Regional Perfusion; Cholinergic Agents; Guanidines; Hippocampus; Memory Disorders; Microglia; Models, Biological; Nicotine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peptide Fragments; Rats

2001
Interaction between synthetic amyloid-beta-peptide (1-40) and its aggregation inhibitors studied by electrospray ionization mass spectrometry.
    Journal of mass spectrometry : JMS, 2001, Volume: 36, Issue:11

    Topics: Amino Acid Sequence; Amyloid beta-Peptides; Antioxidants; Melatonin; Molecular Sequence Data; Nicotine; Peptide Fragments; Spectrometry, Mass, Electrospray Ionization

2001
Chronic nicotine treatment reduces beta-amyloidosis in the brain of a mouse model of Alzheimer's disease (APPsw).
    Journal of neurochemistry, 2002, Volume: 81, Issue:3

    Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Brain Chemistry; Cell Count; Cerebral Cortex; Disease Models, Animal; Disease Progression; Drug Administration Schedule; Female; Glial Fibrillary Acidic Protein; Hippocampus; Humans; Immunohistochemistry; Male; Mice; Mice, Transgenic; Nicotine; Olfactory Pathways; Peptide Fragments; Plaque, Amyloid; Sex Factors; Treatment Outcome

2002
Differential physiologic responses of alpha7 nicotinic acetylcholine receptors to beta-amyloid1-40 and beta-amyloid1-42.
    Journal of neurobiology, 2003, Volume: 55, Issue:1

    Topics: Acetylcholine; Alkaloids; Amyloid beta-Peptides; Animals; Atropine; Azocines; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channel Blockers; Conotoxins; Dose-Response Relationship, Drug; Frontal Lobe; In Vitro Techniques; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Peptide Fragments; Potassium; Pyridines; Quinolizines; Rats; Receptors, Nicotinic; Subcellular Fractions; Synaptosomes

2003
Nicotine enhances the depressive actions of A beta 1-40 on long-term potentiation in the rat hippocampal CA1 region in vivo.
    Journal of neurophysiology, 2003, Volume: 89, Issue:6

    Topics: Aconitine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Electrophysiology; Hippocampus; Injections, Intraventricular; Long-Term Potentiation; Male; Neuronal Plasticity; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Peptide Fragments; Rats; Rats, Wistar; Receptors, Nicotinic

2003
Glycation of the amyloid beta-protein by a nicotine metabolite: a fortuitous chemical dynamic between smoking and Alzheimer's disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Jul-08, Volume: 100, Issue:14

    Topics: Alzheimer Disease; Amino Acid Motifs; Amino Acid Sequence; Amyloid beta-Peptides; Glucose; Glycosylation; Humans; Lysine; Molecular Sequence Data; Neuroprotective Agents; Nicotine; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peptide Fragments; Smoking; Solubility

2003
Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors.
    Neuropharmacology, 2004, Volume: 46, Issue:1

    Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Apoptosis; Blotting, Western; Bungarotoxins; Calcium; Cattle; Cell Line, Tumor; Cholinesterase Inhibitors; Chromaffin Cells; Drug Interactions; Enzyme Inhibitors; Flow Cytometry; Fura-2; Galantamine; Humans; Immunohistochemistry; Neuroblastoma; Nicotine; Peptide Fragments; Proto-Oncogene Proteins c-bcl-2; Rats; Receptors, Nicotinic; Thapsigargin

2004
Both the D-(+) and L-(-) enantiomers of nicotine inhibit Abeta aggregation and cytotoxicity.
    Biochemistry, 2004, Jan-27, Volume: 43, Issue:3

    Topics: Amyloid beta-Peptides; Cell Line, Tumor; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Growth Inhibitors; Humans; Hydroxyl Radical; Neuroblastoma; Nicotine; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Spin Labels; Stereoisomerism; Tetrazolium Salts

2004
Reduced levels of Abeta 40 and Abeta 42 in brains of smoking controls and Alzheimer's patients.
    Neurobiology of disease, 2004, Volume: 15, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Binding Sites; Brain; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Cystine; Down-Regulation; Humans; Iodine Radioisotopes; Middle Aged; Nicotine; Nicotinic Agonists; Peptide Fragments; Pyridines; Radioligand Assay; Receptors, Nicotinic; Smoking; Tritium

2004
Two-site binding of beta-cyclodextrin to the Alzheimer Abeta(1-40) peptide measured with combined PFG-NMR diffusion and induced chemical shifts.
    Biochemistry, 2004, May-25, Volume: 43, Issue:20

    Topics: Alzheimer Disease; Amyloid beta-Peptides; beta-Cyclodextrins; Binding Sites; Cyclodextrins; Humans; Models, Molecular; Nicotine; Nicotinic Agonists; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Binding; Protein Structure, Tertiary

2004
Nicotine reduces A beta in the brain and cerebral vessels of APPsw mice.
    The European journal of neuroscience, 2004, Volume: 19, Issue:10

    Topics: Age Factors; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Blood Vessels; Blotting, Western; Brain; Brain Chemistry; Brain-Derived Neurotrophic Factor; Bungarotoxins; Cell Line, Tumor; Cerebral Arteries; Drug Administration Schedule; Embryo, Mammalian; Endopeptidases; Glucose Transporter Type 1; Humans; Immunohistochemistry; Iodine Isotopes; Mice; Mice, Inbred C57BL; Mice, Transgenic; Monosaccharide Transport Proteins; Nerve Growth Factor; Neuroblastoma; Nicotine; Peptide Fragments

2004
MAPK recruitment by beta-amyloid in organotypic hippocampal slice cultures depends on physical state and exposure time.
    Journal of neurochemistry, 2004, Volume: 91, Issue:2

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Macromolecular Substances; Mitogen-Activated Protein Kinases; Nicotine; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Time Factors

2004
Statins prevent beta-amyloid inhibition of sympathetic alpha7-nAChR-mediated nitrergic neurogenic dilation in porcine basilar arteries.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2005, Volume: 25, Issue:12

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Basilar Artery; Calcium; Cells, Cultured; Choline; Drug Interactions; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Isoproterenol; Lovastatin; Male; Nicotine; Nicotinic Agonists; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Nootropic Agents; Peptide Fragments; Receptors, Nicotinic; Superior Cervical Ganglion; Swine; Sympathetic Nervous System; Sympathomimetics; Vasodilation

2005
Effect of subchronic treatment of memantine, galantamine, and nicotine in the brain of Tg2576 (APPswe) transgenic mice.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 317, Issue:1

    Topics: Amyloid beta-Peptides; Animals; Binding Sites; Blotting, Western; Cerebral Cortex; Cholinesterase Inhibitors; Excitatory Amino Acid Antagonists; Galantamine; Immunohistochemistry; Memantine; Mice; Mice, Transgenic; Nicotine; Peptide Fragments; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Synaptophysin

2006
Inhibition of neprilysin by infusion of thiorphan into the hippocampus causes an accumulation of amyloid Beta and impairment of learning and memory.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 317, Issue:1

    Topics: Acetylcholine; Amyloid beta-Peptides; Animals; Enzyme Inhibitors; Hippocampus; Infusions, Parenteral; Male; Maze Learning; Memory; Motor Activity; Neprilysin; Nicotine; Peptide Fragments; Rats; Rats, Wistar; Thiorphan

2006
Nicotine attenuates beta-amyloid-induced neurotoxicity by regulating metal homeostasis.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:8

    Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Cell Survival; Copper; Hippocampus; Homeostasis; Humans; Metals; Mice; Mice, Transgenic; Molecular Chaperones; Neuroprotective Agents; Nicotine; Peptide Fragments; Plaque, Amyloid; Reactive Oxygen Species; Receptors, Nicotinic; Superoxide Dismutase; Superoxide Dismutase-1

2006
Electrochemical impedance spectroscopy for study of amyloid beta-peptide interactions with (-) nicotine ditartrate and (-) cotinine.
    Biosensors & bioelectronics, 2007, Apr-15, Volume: 22, Issue:9-10

    Topics: Amyloid beta-Peptides; Cotinine; Electric Impedance; Electrodes; Gold Colloid; Nicotine; Peptide Fragments; Spectrum Analysis

2007
Absence of effect of chronic nicotine administration on amyloid beta peptide levels in transgenic mice overexpressing mutated human APP (Sw, Ind).
    Neuroscience letters, 2008, Dec-26, Volume: 448, Issue:2

    Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Blotting, Western; Cerebral Cortex; Enzyme-Linked Immunosorbent Assay; Female; Glial Fibrillary Acidic Protein; Hippocampus; Humans; Male; Mice; Mice, Transgenic; Microfilament Proteins; Mutation; Nicotine; Nicotinic Agonists; Peptide Fragments; Protease Nexins; Receptors, Cell Surface; Receptors, Nicotinic

2008
Association constants of pyridine and piperidine alkaloids to amyloid beta peptide determined by electrochemical impedance spectroscopy.
    Current Alzheimer research, 2010, Volume: 7, Issue:2

    Topics: Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Binding, Competitive; Blood-Brain Barrier; Brain; Brain Chemistry; Electric Impedance; Electrochemistry; Electrodes; Humans; Microscopy; Nicotine; Peptide Fragments; Piperidines; Pyridines

2010
Different β-amyloid oligomer assemblies in Alzheimer brains correlate with age of disease onset and impaired cholinergic activity.
    Neurobiology of aging, 2012, Volume: 33, Issue:4

    Topics: Age Factors; Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Apolipoproteins E; Benzothiazoles; Brain; Cholinergic Agents; Enzyme-Linked Immunosorbent Assay; Female; Genotype; Humans; Immunoprecipitation; Male; Middle Aged; Nicotine; Nicotinic Agonists; Peptide Fragments; Postmortem Changes; Protein Binding; Statistics as Topic; Thiazoles; Tritium

2012
Rescue of amyloid-Beta-induced inhibition of nicotinic acetylcholine receptors by a peptide homologous to the nicotine binding domain of the alpha 7 subtype.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Gene Expression Regulation; HEK293 Cells; Humans; Nicotine; Nicotinic Antagonists; Oligopeptides; PC12 Cells; Peptide Fragments; Protein Structure, Tertiary; Rats

2013
Inhibitory effects of beta-amyloid on the nicotinic receptors which stimulate glutamate release in rat hippocampus: the glial contribution.
    European journal of pharmacology, 2014, Jan-15, Volume: 723

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Aspartic Acid; Azetidines; Bridged Bicyclo Compounds, Heterocyclic; Choline; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Peptide Fragments; Pyridines; Quinuclidines; Rats; Rats, Wistar; Receptors, Nicotinic

2014
Arctic Aβ40 blocks the nicotine-induced neuroprotective effect of CHRNA7 by inhibiting the ERK1/2 pathway in human neuroblastoma cells.
    Neurochemistry international, 2017, Volume: 110

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Cell Line, Tumor; Cell Survival; Humans; MAP Kinase Signaling System; Neuroblastoma; Neuroprotective Agents; Nicotine; Peptide Fragments

2017
Aβ1-16 controls synaptic vesicle pools at excitatory synapses via cholinergic modulation of synapsin phosphorylation.
    Cellular and molecular life sciences : CMLS, 2021, Volume: 78, Issue:11

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Calcium; Excitatory Postsynaptic Potentials; Female; Humans; Mice; Mice, Knockout; Neurons; Neurotransmitter Agents; Nicotine; Peptide Fragments; Phosphorylation; Rats; Rats, Sprague-Dawley; Synapses; Synapsins; Synaptic Vesicles

2021